Result of FASTA (omim) for
pF1KB4448
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4448, 173 aa
1>>>pF1KB4448 173 - 173 aa - 173 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1516+/-0.000445; mu= 14.4698+/- 0.028
mean_var=92.6463+/-18.935, 0's: 0 Z-trim(111.6): 118 B-trim: 12 in 1/50
Lambda= 0.133248
statistics sampled from 20168 (20303) to 20168 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.238), width: 16
Scan time: 5.360
The best scores are: opt bits E(85289)
NP_002468 (OMIM: 160782) myosin light chain 5 [Hom ( 173) 1099 221.2 6.8e-58
XP_016863734 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 1099 221.2 6.8e-58
XP_016863735 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 1099 221.2 6.8e-58
XP_006713949 (OMIM: 160782) PREDICTED: myosin ligh ( 328) 1092 220.1 2.7e-57
XP_016863736 (OMIM: 160782) PREDICTED: myosin ligh ( 132) 847 172.6 2.2e-43
XP_016863737 (OMIM: 160782) PREDICTED: myosin ligh ( 132) 847 172.6 2.2e-43
NP_000423 (OMIM: 160781,608758) myosin regulatory ( 166) 743 152.7 2.6e-37
NP_067046 (OMIM: 613993) myosin regulatory light c ( 175) 736 151.4 7e-37
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 610 127.1 1.3e-29
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 610 127.1 1.3e-29
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 610 127.1 1.3e-29
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 597 124.6 7.6e-29
XP_011513766 (OMIM: 613993) PREDICTED: myosin regu ( 208) 587 122.8 3.3e-28
XP_016867967 (OMIM: 613993) PREDICTED: myosin regu ( 132) 532 112.0 3.7e-25
XP_011513767 (OMIM: 613993) PREDICTED: myosin regu ( 163) 530 111.7 5.5e-25
XP_016867968 (OMIM: 613993) PREDICTED: myosin regu ( 99) 445 95.2 3.3e-20
XP_011513765 (OMIM: 613993) PREDICTED: myosin regu ( 231) 448 96.1 3.9e-20
XP_005249874 (OMIM: 613993) PREDICTED: myosin regu ( 155) 393 85.4 4.5e-17
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 314 70.2 1.6e-12
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 314 70.2 1.6e-12
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 314 70.2 1.6e-12
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 314 70.2 1.6e-12
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 314 70.2 1.6e-12
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 314 70.3 2e-12
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 293 66.1 2.7e-11
NP_852667 (OMIM: 609905) myosin regulatory light p ( 118) 271 61.8 4.3e-10
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 266 61.0 1.1e-09
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 253 58.5 6.1e-09
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 227 53.3 1.5e-07
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 227 53.3 1.5e-07
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 227 53.3 1.5e-07
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 227 53.3 1.5e-07
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 227 53.3 1.5e-07
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 227 53.3 1.5e-07
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 227 53.3 1.5e-07
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 221 52.4 4.3e-07
NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [H ( 191) 213 50.9 1.4e-06
NP_001186558 (OMIM: 609930) myosin light chain 6B ( 208) 207 49.8 3.2e-06
NP_002466 (OMIM: 609930) myosin light chain 6B [Ho ( 208) 207 49.8 3.2e-06
NP_062829 (OMIM: 607315) calcium-binding protein 5 ( 173) 195 47.4 1.4e-05
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 192 46.7 1.9e-05
XP_016882481 (OMIM: 607315) PREDICTED: calcium-bin ( 284) 195 47.6 2e-05
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 192 46.8 2e-05
NP_059118 (OMIM: 605183) calmodulin-like protein 5 ( 146) 190 46.3 2.4e-05
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 191 46.6 2.5e-05
NP_057450 (OMIM: 607314,614899) calcium-binding pr ( 220) 192 46.9 2.5e-05
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 191 46.7 2.7e-05
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 189 46.2 3e-05
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 188 45.9 3.2e-05
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 188 46.0 3.2e-05
>>NP_002468 (OMIM: 160782) myosin light chain 5 [Homo sa (173 aa)
initn: 1099 init1: 1099 opt: 1099 Z-score: 1160.4 bits: 221.2 E(85289): 6.8e-58
Smith-Waterman score: 1099; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB4 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
70 80 90 100 110 120
130 140 150 160 170
pF1KB4 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
130 140 150 160 170
>>XP_016863734 (OMIM: 160782) PREDICTED: myosin light ch (173 aa)
initn: 1099 init1: 1099 opt: 1099 Z-score: 1160.4 bits: 221.2 E(85289): 6.8e-58
Smith-Waterman score: 1099; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB4 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
70 80 90 100 110 120
130 140 150 160 170
pF1KB4 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
130 140 150 160 170
>>XP_016863735 (OMIM: 160782) PREDICTED: myosin light ch (173 aa)
initn: 1099 init1: 1099 opt: 1099 Z-score: 1160.4 bits: 221.2 E(85289): 6.8e-58
Smith-Waterman score: 1099; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB4 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
70 80 90 100 110 120
130 140 150 160 170
pF1KB4 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
130 140 150 160 170
>>XP_006713949 (OMIM: 160782) PREDICTED: myosin light ch (328 aa)
initn: 1092 init1: 1092 opt: 1092 Z-score: 1149.7 bits: 220.1 E(85289): 2.7e-57
Smith-Waterman score: 1092; 100.0% identity (100.0% similar) in 172 aa overlap (2-173:157-328)
10 20 30
pF1KB4 MASRKTKKKEGGALRAQRASSNVFSNFEQTQ
::::::::::::::::::::::::::::::
XP_006 PPSASWPCVHTPDCGPGRTLSSCAERRRPEASRKTKKKEGGALRAQRASSNVFSNFEQTQ
130 140 150 160 170 180
40 50 60 70 80 90
pF1KB4 IQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKEASGPINFTMFLNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKEASGPINFTMFLNL
190 200 210 220 230 240
100 110 120 130 140 150
pF1KB4 FGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFASID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFASID
250 260 270 280 290 300
160 170
pF1KB4 VAGNLDYKALSYVITHGEEKEE
::::::::::::::::::::::
XP_006 VAGNLDYKALSYVITHGEEKEE
310 320
>>XP_016863736 (OMIM: 160782) PREDICTED: myosin light ch (132 aa)
initn: 847 init1: 847 opt: 847 Z-score: 900.0 bits: 172.6 E(85289): 2.2e-43
Smith-Waterman score: 847; 100.0% identity (100.0% similar) in 132 aa overlap (42-173:1-132)
20 30 40 50 60 70
pF1KB4 GALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDE
::::::::::::::::::::::::::::::
XP_016 MDQNRDGFIDKEDLKDTYASLGKTNVKDDE
10 20 30
80 90 100 110 120 130
pF1KB4 LDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMS
40 50 60 70 80 90
140 150 160 170
pF1KB4 QADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
::::::::::::::::::::::::::::::::::::::::::
XP_016 QADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
100 110 120 130
>>XP_016863737 (OMIM: 160782) PREDICTED: myosin light ch (132 aa)
initn: 847 init1: 847 opt: 847 Z-score: 900.0 bits: 172.6 E(85289): 2.2e-43
Smith-Waterman score: 847; 100.0% identity (100.0% similar) in 132 aa overlap (42-173:1-132)
20 30 40 50 60 70
pF1KB4 GALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDE
::::::::::::::::::::::::::::::
XP_016 MDQNRDGFIDKEDLKDTYASLGKTNVKDDE
10 20 30
80 90 100 110 120 130
pF1KB4 LDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMS
40 50 60 70 80 90
140 150 160 170
pF1KB4 QADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
::::::::::::::::::::::::::::::::::::::::::
XP_016 QADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
100 110 120 130
>>NP_000423 (OMIM: 160781,608758) myosin regulatory ligh (166 aa)
initn: 780 init1: 722 opt: 743 Z-score: 790.7 bits: 152.7 E(85289): 2.6e-37
Smith-Waterman score: 743; 64.0% identity (86.6% similar) in 172 aa overlap (1-172:1-166)
10 20 30 40 50 60
pF1KB4 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
:: .:.::. ::: .::::: ::::::::::::::.:::::::::::.::.::.:
NP_000 MAPKKAKKRAGGA------NSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFA
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
.::..:::..:.: :.::: ::::::.::..:::::.:.: :::::::::..::.::: .
NP_000 ALGRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVL
60 70 80 90 100 110
130 140 150 160 170
pF1KB4 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
. .:....: .::.... ::::::: ::.:::::: : ..:::::::.
NP_000 KADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
120 130 140 150 160
>>NP_067046 (OMIM: 613993) myosin regulatory light chain (175 aa)
initn: 730 init1: 714 opt: 736 Z-score: 783.2 bits: 151.4 E(85289): 7e-37
Smith-Waterman score: 736; 63.4% identity (89.7% similar) in 175 aa overlap (1-173:1-175)
10 20 30 40 50
pF1KB4 MASRK--TKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT
::::: :. : ... .:::.:::::: :::.:::::::::. .::::::.: : ::..:
NP_067 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG
:..:::..: ..::::::.:..::::::.::.::::::.::: ::.::.::.:.::.:::
NP_067 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
.::. .:.::..::::.. ::.::: .. .:.:::.:::.: :.::::.::::
NP_067 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
130 140 150 160 170
>>NP_001138416 (OMIM: 609211) myosin regulatory light ch (172 aa)
initn: 586 init1: 341 opt: 610 Z-score: 652.4 bits: 127.1 E(85289): 1.3e-29
Smith-Waterman score: 610; 53.8% identity (79.8% similar) in 173 aa overlap (1-173:1-171)
10 20 30 40 50 60
pF1KB4 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
:.:.:.: : : :::.::::. :.:.:::::::::...:::::::::::::.: :
NP_001 MSSKKAKTKTTKK-RPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
:::: : : ::::..:: :::::::::..:::::.::: :..: ::: .: .. : :
NP_001 SLGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTI
60 70 80 90 100 110
130 140 150 160 170
pF1KB4 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
...:...:: ...:..: ::::.... : :: ::..: .. .. :: . ..
NP_001 QEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
120 130 140 150 160 170
>>NP_001138417 (OMIM: 609211) myosin regulatory light ch (172 aa)
initn: 586 init1: 341 opt: 610 Z-score: 652.4 bits: 127.1 E(85289): 1.3e-29
Smith-Waterman score: 610; 53.8% identity (79.8% similar) in 173 aa overlap (1-173:1-171)
10 20 30 40 50 60
pF1KB4 MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
:.:.:.: : : :::.::::. :.:.:::::::::...:::::::::::::.: :
NP_001 MSSKKAKTKTTKK-RPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLA
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
:::: : : ::::..:: :::::::::..:::::.::: :..: ::: .: .. : :
NP_001 SLGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTI
60 70 80 90 100 110
130 140 150 160 170
pF1KB4 NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
...:...:: ...:..: ::::.... : :: ::..: .. .. :: . ..
NP_001 QEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
120 130 140 150 160 170
173 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:18:18 2016 done: Fri Nov 4 18:18:19 2016
Total Scan time: 5.360 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]