Result of FASTA (ccds) for
pF1KB4426
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4426, 272 aa
1>>>pF1KB4426 272 - 272 aa - 272 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2680+/-0.000752; mu= 17.4972+/- 0.046
mean_var=106.9159+/-20.664, 0's: 0 Z-trim(112.8): 46 B-trim: 51 in 1/50
Lambda= 0.124038
statistics sampled from 13440 (13486) to 13440 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.414), width: 16
Scan time: 2.430
The best scores are: opt bits E(32554)
CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2 ( 272) 1915 352.5 1.8e-97
CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7 ( 291) 806 154.1 1e-37
CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17 ( 258) 450 90.4 1.4e-18
CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7 ( 297) 405 82.4 4.2e-16
CCDS5504.1 IGFBP1 gene_id:3484|Hs108|chr7 ( 259) 346 71.8 5.8e-13
CCDS8846.1 IGFBP6 gene_id:3489|Hs108|chr12 ( 240) 338 70.3 1.5e-12
>>CCDS2405.1 IGFBP5 gene_id:3488|Hs108|chr2 (272 aa)
initn: 1915 init1: 1915 opt: 1915 Z-score: 1863.4 bits: 352.5 E(32554): 1.8e-97
Smith-Waterman score: 1915; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS24 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS24 LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS24 EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS24 PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI
190 200 210 220 230 240
250 260 270
pF1KB4 CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
::::::::::::::::::::::::::::::::
CCDS24 CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
250 260 270
>>CCDS5505.1 IGFBP3 gene_id:3486|Hs108|chr7 (291 aa)
initn: 812 init1: 372 opt: 806 Z-score: 790.5 bits: 154.1 E(32554): 1e-37
Smith-Waterman score: 817; 44.0% identity (67.6% similar) in 293 aa overlap (3-268:8-290)
10 20 30 40
pF1KB4 MVLLTAVLLLLAAYAGP------AQS--LGSFVHCEPCDEKALSMCPPSPLGC-E
: .:.: ::. :: :.: :: :.::::: .::..: : : : :
CCDS55 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB4 LVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSY
::.:::::::.::::.::: ::.:::::..:::: : :: .::.::: :::.:.: ..
CCDS55 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
70 80 90 100 110 120
110 120 130 140 150
pF1KB4 RE----------------QVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAE
. . . .:.. : :..: .... .:: :.: :..: .:
CCDS55 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSS-THRVSDPK-FHPLHSKIIIIKKG
130 140 150 160 170
160 170 180 190 200 210
pF1KB4 AVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMV
.: ..: :. . ..: . : ..:.: :::::.:: .:..:: .
CCDS55 HAKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFLNVLS
180 190 200 210 220 230
220 230 240 250 260
pF1KB4 PRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDG--DFQCHTFDS
::.:..::::.:::::.:::.::.:::::.::::::::. :::. . : : .:....:
CCDS55 PRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYT-TKGKEDVHCYSMQS
240 250 260 270 280 290
270
pF1KB4 SNVE
CCDS55 K
>>CCDS11367.1 IGFBP4 gene_id:3487|Hs108|chr17 (258 aa)
initn: 623 init1: 373 opt: 450 Z-score: 446.9 bits: 90.4 E(32554): 1.4e-18
Smith-Waterman score: 658; 40.8% identity (62.8% similar) in 277 aa overlap (1-269:1-255)
10 20 30 40 50
pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSF-VHCEPCDEKALSMCPPSPLGCE-LVKEPGCGCCMT
:. : : :: : :::. :::. .:: ::.:. :. : : :.::: ::.::::::: :
CCDS11 MLPLCLVAALLLA-AGPGPSLGDEAIHCPPCSEEKLARCRP-PVGCEELVREPGCGCCAT
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIE--RDS
:::. :. ::::: ::..:::: : . :::::.:.::.:::. : ..:: ..:
CCDS11 CALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCM------ELAEIEAIQES
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 REHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPR
. . .. ....:: : : : : .:: . . : :. .. :.:
CCDS11 LQPSDKDEGDHPNNSFSPC---SAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARP-
120 130 140 150 160
180 190 200 210 220 230
pF1KB4 IISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYL---PNCDRKGFYKRKQCKPS
.: :: :. ... .:..: :: . . .:. :::::.: .. :::.:.
CCDS11 ---VP-------QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPA
170 180 190 200 210
240 250 260 270
pF1KB4 RGRKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFDSSNVE
.:: ::::: : :.:::: :...:: . .:
CCDS11 LDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE
220 230 240 250
>>CCDS34632.1 IGFBP3 gene_id:3486|Hs108|chr7 (297 aa)
initn: 709 init1: 372 opt: 405 Z-score: 402.6 bits: 82.4 E(32554): 4.2e-16
Smith-Waterman score: 806; 44.1% identity (66.0% similar) in 297 aa overlap (3-268:8-296)
10 20 30 40
pF1KB4 MVLLTAVLLLLAAYAGP------AQS--LGSFVHCEPCDEKALSMCPPSPLGC-E
: .:.: ::. :: :.: :: :.::::: .::..: : : : :
CCDS34 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB4 LVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSY
::.:::::::.::::.::: ::.:::::..:::: : :: .::.::: :::.:.: ..
CCDS34 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
70 80 90 100 110 120
110 120 130 140
pF1KB4 -REQVKIERDSREHEEP----TTSEMAEE-----TYSPKI----------FRPKHTRISE
: .. . :: ..:: :. . ::.. :.: :..:
CCDS34 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB4 LKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKAS
.: .: ..: :. . ..: . : ..:.: :::::.:: .:..::
CCDS34 IKKGHAKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFL
190 200 210 220 230
210 220 230 240 250 260
pF1KB4 PRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDG--DFQCH
. ::.:..::::.:::::.:::.::.:::::.::::::::. :::. . : : .:.
CCDS34 NVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYT-TKGKEDVHCY
240 250 260 270 280 290
270
pF1KB4 TFDSSNVE
...:
CCDS34 SMQSK
>>CCDS5504.1 IGFBP1 gene_id:3484|Hs108|chr7 (259 aa)
initn: 470 init1: 241 opt: 346 Z-score: 346.3 bits: 71.8 E(32554): 5.8e-13
Smith-Waterman score: 495; 32.0% identity (58.3% similar) in 266 aa overlap (7-266:12-254)
10 20 30 40 50
pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGC-ELVKEPGCG
:::::.. .: . :. .: ::. . :..::: .: :... :::
CCDS55 MSEVPVARVWLVLLLLTVQVG--VTAGAPWQCAPCSAEKLALCPPVSASCSEVTRSAGCG
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 CCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIER
:: ::: : .::: : :::.:: : :..::::: .:.:.:..:.. :
CCDS55 CCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 DSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAH
: : : ..:..:: ... : . ... : . : . :.
CCDS55 GS--PESPESTEITEE----ELLDNFHLMAPSEEDHSILWD-----AISTYDGS------
120 130 140 150 160
180 190 200 210 220 230
pF1KB4 PRIISAPEMRQESEQGPCR----RHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQC
. . . .... .: ::: : .:. . ..: . . . :::::...:::. .::
CCDS55 -KALHVTNIKKWKE--PCRIELYRVVESLAKAQETSGEEISK-FYLPNCNKNGFYHSRQC
170 180 190 200 210
240 250 260 270
pF1KB4 KPSRGRKRGICWCVDKY-GMKLPGMEYVDGDFQCHTFDSSNVE
. : . :.:::: . : ..:: . :: .:. .
CCDS55 ETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFNVQN
220 230 240 250
>>CCDS8846.1 IGFBP6 gene_id:3489|Hs108|chr12 (240 aa)
initn: 586 init1: 308 opt: 338 Z-score: 338.9 bits: 70.3 E(32554): 1.5e-12
Smith-Waterman score: 531; 35.1% identity (59.7% similar) in 268 aa overlap (3-268:6-239)
10 20 30 40 50
pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCM
:: .::::: . :. :....: : . . . :: . . : :. ::
CCDS88 MTPHRLLPPLLLLLALLLA-ASPGGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAE
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 T--CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERD
. : ::: ::::: :: ::.: : .:.: ::.::: ::: :: ..
CCDS88 AEGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARA----------
60 70 80 90 100
120 130 140 150 160 170
pF1KB4 SREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHP
:. .::: .:: .:. . : .: .. :.. : . . ..:
CCDS88 ------PA---VAEE--NPKESKPQ-------AGTARPQDVNRR-DQQRNPGTSTTPSQP
110 120 130 140 150
180 190 200 210 220 230
pF1KB4 RIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRG
.. :..:.::::::... ::.:.. ...:.::::..:::...::. :.:
CCDS88 NSAGV----QDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQG
160 170 180 190 200
240 250 260 270
pF1KB4 RKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
..:: :::::..: .::: .:. .: : .:
CCDS88 QRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG
210 220 230 240
272 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:00:51 2016 done: Fri Nov 4 03:00:51 2016
Total Scan time: 2.430 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]