Result of FASTA (omim) for
pF1KB4334
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4334, 473 aa
1>>>pF1KB4334 473 - 473 aa - 473 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9176+/-0.000477; mu= 14.0117+/- 0.029
mean_var=70.2006+/-14.510, 0's: 0 Z-trim(108.8): 156 B-trim: 0 in 0/53
Lambda= 0.153075
statistics sampled from 16686 (16870) to 16686 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.543), E-opt: 0.2 (0.198), width: 16
Scan time: 8.400
The best scores are: opt bits E(85289)
NP_000805 (OMIM: 137192,612269,617113) gamma-amino ( 473) 3163 708.3 1.1e-203
NP_068712 (OMIM: 137192,612269,617113) gamma-amino ( 473) 2979 667.7 1.9e-191
XP_011519730 (OMIM: 137192,612269,617113) PREDICTE ( 414) 2614 587.1 3.2e-167
NP_001178250 (OMIM: 137192,612269,617113) gamma-am ( 402) 2613 586.8 3.6e-167
NP_001178249 (OMIM: 137192,612269,617113) gamma-am ( 388) 2582 580.0 4e-165
NP_001265560 (OMIM: 137192,612269,617113) gamma-am ( 388) 2582 580.0 4e-165
NP_000804 (OMIM: 600232) gamma-aminobutyric acid r ( 474) 2552 573.4 4.7e-163
NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474) 2461 553.3 5.3e-157
NP_068711 (OMIM: 600232) gamma-aminobutyric acid r ( 512) 2088 470.9 3.6e-132
XP_011529486 (OMIM: 300349) PREDICTED: gamma-amino ( 406) 1218 278.8 2e-74
NP_061028 (OMIM: 300349) gamma-aminobutyric acid r ( 632) 1218 278.8 3e-74
XP_016863474 (OMIM: 137190,617153) PREDICTED: gamm ( 257) 1188 272.1 1.3e-72
XP_016856425 (OMIM: 137163,613060) PREDICTED: gamm ( 687) 1099 252.6 2.6e-66
NP_000806 (OMIM: 137163,613060) gamma-aminobutyric ( 452) 1077 247.6 5.2e-65
XP_011539496 (OMIM: 137163,613060) PREDICTED: gamm ( 465) 1077 247.6 5.3e-65
NP_001243632 (OMIM: 137161) gamma-aminobutyric aci ( 462) 1039 239.2 1.8e-62
NP_002033 (OMIM: 137161) gamma-aminobutyric acid r ( 479) 1039 239.3 1.8e-62
NP_001254511 (OMIM: 137161) gamma-aminobutyric aci ( 392) 1028 236.8 8.2e-62
XP_016866178 (OMIM: 137161) PREDICTED: gamma-amino ( 392) 1028 236.8 8.2e-62
NP_001243633 (OMIM: 137161) gamma-aminobutyric aci ( 392) 1028 236.8 8.2e-62
NP_002034 (OMIM: 137162) gamma-aminobutyric acid r ( 465) 1028 236.8 9.6e-62
NP_055026 (OMIM: 602729) gamma-aminobutyric acid r ( 440) 1009 232.6 1.7e-60
XP_011534015 (OMIM: 137162) PREDICTED: gamma-amino ( 421) 985 227.3 6.3e-59
XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436) 959 221.6 3.5e-57
XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436) 959 221.6 3.5e-57
XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436) 959 221.6 3.5e-57
NP_001112357 (OMIM: 305990) glycine receptor subun ( 452) 959 221.6 3.6e-57
NP_002054 (OMIM: 305990) glycine receptor subunit ( 452) 959 221.6 3.6e-57
NP_001112358 (OMIM: 305990) glycine receptor subun ( 452) 957 221.1 4.9e-57
XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452) 957 221.1 4.9e-57
NP_001036008 (OMIM: 600421) glycine receptor subun ( 449) 940 217.4 6.6e-56
NP_006520 (OMIM: 600421) glycine receptor subunit ( 464) 940 217.4 6.8e-56
XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424) 938 216.9 8.5e-56
NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449) 935 216.3 1.4e-55
XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465) 935 216.3 1.5e-55
NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457) 926 214.3 5.7e-55
NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467) 920 213.0 1.5e-54
NP_000815 (OMIM: 138492,614619) glycine receptor s ( 497) 916 212.1 2.9e-54
NP_001159532 (OMIM: 138492,614619) glycine recepto ( 497) 916 212.1 2.9e-54
NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475) 915 211.9 3.2e-54
XP_016863475 (OMIM: 137190,617153) PREDICTED: gamm ( 247) 892 206.7 6e-53
NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465) 889 206.1 1.7e-52
XP_011534018 (OMIM: 137162) PREDICTED: gamma-amino ( 366) 886 205.4 2.1e-52
XP_011534019 (OMIM: 137162) PREDICTED: gamma-amino ( 366) 886 205.4 2.1e-52
XP_011534016 (OMIM: 137162) PREDICTED: gamma-amino ( 366) 886 205.4 2.1e-52
XP_011534017 (OMIM: 137162) PREDICTED: gamma-amino ( 366) 886 205.4 2.1e-52
XP_005265929 (OMIM: 602729) PREDICTED: gamma-amino ( 361) 878 203.7 7.2e-52
XP_005268315 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 877 203.5 1e-51
NP_001158509 (OMIM: 137142) gamma-aminobutyric aci ( 462) 877 203.5 1e-51
NP_000801 (OMIM: 137142) gamma-aminobutyric acid r ( 462) 877 203.5 1e-51
>>NP_000805 (OMIM: 137192,612269,617113) gamma-aminobuty (473 aa)
initn: 3163 init1: 3163 opt: 3163 Z-score: 3777.5 bits: 708.3 E(85289): 1.1e-203
Smith-Waterman score: 3163; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473)
10 20 30 40 50 60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS
370 380 390 400 410 420
430 440 450 460 470
pF1KB4 LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
430 440 450 460 470
>>NP_068712 (OMIM: 137192,612269,617113) gamma-aminobuty (473 aa)
initn: 2979 init1: 2979 opt: 2979 Z-score: 3557.9 bits: 667.7 E(85289): 1.9e-191
Smith-Waterman score: 2979; 99.8% identity (100.0% similar) in 448 aa overlap (26-473:26-473)
10 20 30 40 50 60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
.::::::::::::::::::::::::::::::::::
NP_068 MCSGLLELLLPIWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS
370 380 390 400 410 420
430 440 450 460 470
pF1KB4 LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
430 440 450 460 470
>>XP_011519730 (OMIM: 137192,612269,617113) PREDICTED: g (414 aa)
initn: 2614 init1: 2614 opt: 2614 Z-score: 3123.2 bits: 587.1 E(85289): 3.2e-167
Smith-Waterman score: 2614; 99.2% identity (99.5% similar) in 396 aa overlap (78-473:19-414)
50 60 70 80 90 100
pF1KB4 YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLT
. :::::::::::::::::::::::::::
XP_011 MQIPSLCDCALLFGSCHIIAKDYTLTMYFQQYWRDKRLAYSGIPLNLT
10 20 30 40
110 120 130 140 150 160
pF1KB4 LDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRR
50 60 70 80 90 100
170 180 190 200 210 220
pF1KB4 YPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFAT
110 120 130 140 150 160
230 240 250 260 270 280
pF1KB4 GAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMT
170 180 190 200 210 220
290 300 310 320 330 340
pF1KB4 TINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTA
230 240 250 260 270 280
350 360 370 380 390 400
pF1KB4 KAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSM
290 300 310 320 330 340
410 420 430 440 450 460
pF1KB4 PREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVY
350 360 370 380 390 400
470
pF1KB4 WLYYVN
::::::
XP_011 WLYYVN
410
>>NP_001178250 (OMIM: 137192,612269,617113) gamma-aminob (402 aa)
initn: 2613 init1: 2613 opt: 2613 Z-score: 3122.2 bits: 586.8 E(85289): 3.6e-167
Smith-Waterman score: 2613; 100.0% identity (100.0% similar) in 393 aa overlap (81-473:10-402)
60 70 80 90 100 110
pF1KB4 RLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDN
::::::::::::::::::::::::::::::
NP_001 MWATYQTEEDYTLTMYFQQYWRDKRLAYSGIPLNLTLDN
10 20 30
120 130 140 150 160 170
pF1KB4 RVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB4 DEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAY
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB4 PRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTIN
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB4 THLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAK
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB4 NDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPRE
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB4 GHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLY
340 350 360 370 380 390
pF1KB4 YVN
:::
NP_001 YVN
400
>>NP_001178249 (OMIM: 137192,612269,617113) gamma-aminob (388 aa)
initn: 2582 init1: 2582 opt: 2582 Z-score: 3085.5 bits: 580.0 E(85289): 4e-165
Smith-Waterman score: 2582; 100.0% identity (100.0% similar) in 388 aa overlap (86-473:1-388)
60 70 80 90 100 110
pF1KB4 FGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
::::::::::::::::::::::::::::::
NP_001 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
10 20 30
120 130 140 150 160 170
pF1KB4 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB4 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB4 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB4 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB4 SESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRF
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB4 LGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
340 350 360 370 380
>>NP_001265560 (OMIM: 137192,612269,617113) gamma-aminob (388 aa)
initn: 2582 init1: 2582 opt: 2582 Z-score: 3085.5 bits: 580.0 E(85289): 4e-165
Smith-Waterman score: 2582; 100.0% identity (100.0% similar) in 388 aa overlap (86-473:1-388)
60 70 80 90 100 110
pF1KB4 FGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
::::::::::::::::::::::::::::::
NP_001 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
10 20 30
120 130 140 150 160 170
pF1KB4 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB4 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB4 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB4 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB4 SESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRF
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB4 LGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
340 350 360 370 380
>>NP_000804 (OMIM: 600232) gamma-aminobutyric acid recep (474 aa)
initn: 2120 init1: 2120 opt: 2552 Z-score: 3048.3 bits: 573.4 E(85289): 4.7e-163
Smith-Waterman score: 2552; 79.8% identity (92.4% similar) in 475 aa overlap (1-473:1-474)
10 20 30 40 50 60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
:: . :::.: :...:.:: :::::::.:::.::::::.:::::::::::::::::
NP_000 MWRVRKRGYFGIWSFPLIIAAVC-AQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
: :::::::::::::::::::::::::::: ::::::.:. :::::::::::::::::::
NP_000 VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
::::::::::::::: :.::::: .:::::::::...:....:::.::.::::::::.::
NP_000 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
::::::::::::::::::.::::::.::::::::::::::: :::.:.:.:.. . . :.
NP_000 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK
300 310 320 330 340 350
370 380 390 400 410
pF1KB4 VDAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGD
.: : ::::..::..::: .:. :.:: :.. ...: :.::::: ..::.. :: .
NP_000 MDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALE
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB4 RSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
: . .::..::::.::::: :::::::::::::::: :: .::.::.::::::::
NP_000 RHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
420 430 440 450 460 470
>>NP_000803 (OMIM: 137190,617153) gamma-aminobutyric aci (474 aa)
initn: 2454 init1: 2090 opt: 2461 Z-score: 2939.6 bits: 553.3 E(85289): 5.3e-157
Smith-Waterman score: 2461; 76.9% identity (91.2% similar) in 477 aa overlap (1-473:1-474)
10 20 30 40 50 60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
:: . . . .:..: ::....::::.:.:.:.:::.::::::.:::::::::::::::::
NP_000 MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
: ::: ::.::::::::::::::::::::: :.::::.::::::::::::::::::::::
NP_000 VDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
::::::::::::: ::. :::::..:::::::::....::..: :.::::::::::::::
NP_000 SYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
:::::::::::::: ::::::::::::::::::::::::::::::::::.::::::::::
NP_000 RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
:::::::.:::::::::::::::::::::::::.::: :: : : .. :...: : :.
NP_000 PYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQ--KKGASKQDQSANEKNKLEMNK
310 320 330 340 350
370 380 390 400 410
pF1KB4 V--DAHGNILLTSLEVHNEMN--EVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFL
: ::::::::..::..:: . :: ...: . . :.:...::::: ::..:: :
NP_000 VQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRAL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB4 GDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
...: .: ..:::.::::.:::::::::.::.:::. ::.::::::.:::::::.
NP_000 DRHGVP-SKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH
420 430 440 450 460 470
>>NP_068711 (OMIM: 600232) gamma-aminobutyric acid recep (512 aa)
initn: 2489 init1: 2040 opt: 2088 Z-score: 2493.9 bits: 470.9 E(85289): 3.6e-132
Smith-Waterman score: 2408; 73.5% identity (85.3% similar) in 505 aa overlap (1-465:1-504)
10 20 30 40 50 60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
:: . :::.: :...:.:: :::::::.:::.::::::.:::::::::::::::::
NP_068 MWRVRKRGYFGIWSFPLIIAAVC-AQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
: :::::::::::::::::::::::::::: ::::::.:. :::::::::::::::::::
NP_068 VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
::::::::::::::: :.::::: .:::::::::...:....:::.::.::::::::.::
NP_068 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
::::::::::::::::::.::::::.::::::::::::::: :::.:.:.:.. . . :.
NP_068 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK
300 310 320 330 340 350
370 380
pF1KB4 V--------------------------------------DAHGNILLTSLEVHNEM--NE
. : : ::::..::..::: .:
NP_068 IFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSE
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB4 VSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIP
. :.:: :.. ...: :.::::: ..::.. :: .: . .::..::::.::::: ::
NP_068 AVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIP
420 430 440 450 460 470
450 460 470
pF1KB4 DLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
:::::::::::::: :: .::.::.
NP_068 DLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
480 490 500 510
>>XP_011529486 (OMIM: 300349) PREDICTED: gamma-aminobuty (406 aa)
initn: 1190 init1: 1190 opt: 1218 Z-score: 1457.2 bits: 278.8 E(85289): 2e-74
Smith-Waterman score: 1218; 50.5% identity (83.7% similar) in 325 aa overlap (17-341:43-363)
10 20 30 40
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLK
:.. . : . .:. . :.. .:..:.
XP_011 LLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANE----AVVQKILDRVLS
20 30 40 50 60
50 60 70 80 90 100
pF1KB4 GYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNL
::.::::.::: :: : ..: ..::...::.:::::.::.:.: :.:.:::: :::
XP_011 RYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTLNL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB4 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR
::: :. ..::::: ::::.: .::: :::.::...::::::: ::.:.:::::: .::.
XP_011 TLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLH
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB4 RYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFA
..:.:.: :.: .::::::..:: ..: . .:. .:....:::... . ..:..: :
XP_011 KFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFY
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB4 TGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTM
::.: :: :.:...:... ...:.: :..: :: ::.:::.:::.:::::..:.:..: .
XP_011 TGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLIL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB4 TTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKT
:::..:::. ::.: .::::.:.. :. ::::.::::...::.:..:::.:: .
XP_011 TTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRP
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB4 AKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQS
XP_011 RRVIARYRYQQVVVGNVQVGMGQASRNPTLIHSPWRSM
370 380 390 400
473 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:48:24 2016 done: Sat Nov 5 05:48:25 2016
Total Scan time: 8.400 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]