FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4277, 425 aa 1>>>pF1KB4277 425 - 425 aa - 425 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5900+/-0.000498; mu= 11.2821+/- 0.030 mean_var=180.3872+/-40.502, 0's: 0 Z-trim(113.6): 248 B-trim: 318 in 1/48 Lambda= 0.095493 statistics sampled from 22665 (23021) to 22665 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.27), width: 16 Scan time: 8.490 The best scores are: opt bits E(85289) NP_005601 (OMIM: 602923) histone-binding protein R ( 425) 2929 416.7 5.8e-116 NP_001128727 (OMIM: 602923) histone-binding protei ( 424) 2912 414.3 2.9e-115 NP_001128728 (OMIM: 602923) histone-binding protei ( 390) 2698 384.8 2.1e-106 NP_002884 (OMIM: 300825) histone-binding protein R ( 425) 2640 376.8 5.6e-104 NP_001185648 (OMIM: 300825) histone-binding protei ( 469) 2629 375.4 1.7e-103 XP_011509771 (OMIM: 616620) PREDICTED: ribosome bi ( 285) 265 49.4 1.4e-05 NP_060726 (OMIM: 616620) ribosome biogenesis prote ( 423) 265 49.6 1.7e-05 XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 251 47.5 5.2e-05 NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 251 47.6 5.6e-05 NP_003301 (OMIM: 608998) protein TSSC1 isoform 2 [ ( 387) 242 46.4 0.00015 NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 239 46.1 0.00021 NP_113673 (OMIM: 610597) glutamate-rich WD repeat- ( 446) 239 46.1 0.00022 NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 239 46.2 0.00024 XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024 XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024 XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024 XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024 NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 239 46.2 0.00024 XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024 XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024 NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 239 46.2 0.00024 NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 235 45.6 0.00033 NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 235 45.6 0.00033 NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 235 45.6 0.00033 NP_001177385 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 235 45.6 0.00033 NP_006082 (OMIM: 605002) coronin-2B isoform 1 [Hom ( 480) 235 45.6 0.00033 NP_942590 (OMIM: 608141) nucleoporin Nup43 [Homo s ( 380) 232 45.0 0.00038 NP_003380 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 233 45.3 0.00042 NP_438171 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 233 45.3 0.00042 XP_011517288 (OMIM: 602159) PREDICTED: coronin-2A ( 525) 233 45.3 0.00042 XP_005267019 (OMIM: 608141) PREDICTED: nucleoporin ( 313) 227 44.2 0.00054 XP_011534101 (OMIM: 608141) PREDICTED: nucleoporin ( 317) 227 44.3 0.00055 XP_005267018 (OMIM: 608141) PREDICTED: nucleoporin ( 333) 227 44.3 0.00057 XP_005267017 (OMIM: 608141) PREDICTED: nucleoporin ( 333) 227 44.3 0.00057 XP_011534100 (OMIM: 608141) PREDICTED: nucleoporin ( 347) 227 44.3 0.00058 NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 229 44.8 0.00062 NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 229 44.8 0.00062 NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 229 44.8 0.00062 XP_005262629 (OMIM: 400033) PREDICTED: F-box-like/ ( 536) 229 44.8 0.00063 XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540) 229 44.8 0.00063 XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577) 229 44.8 0.00066 NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 224 43.8 0.00073 XP_016857569 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 226 44.3 0.00076 XP_016857567 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 226 44.3 0.00076 XP_016857568 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 226 44.3 0.00076 XP_016857566 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 477) 226 44.3 0.00078 NP_001273573 (OMIM: 608067) E3 ubiquitin-protein l ( 491) 226 44.3 0.00079 XP_016857565 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 491) 226 44.3 0.00079 XP_016857564 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 497) 226 44.4 0.0008 XP_016857563 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 507) 226 44.4 0.00081 >>NP_005601 (OMIM: 602923) histone-binding protein RBBP4 (425 aa) initn: 2929 init1: 2929 opt: 2929 Z-score: 2202.9 bits: 416.7 E(85289): 5.8e-116 Smith-Waterman score: 2929; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP 370 380 390 400 410 420 pF1KB4 EGQGS ::::: NP_005 EGQGS >>NP_001128727 (OMIM: 602923) histone-binding protein RB (424 aa) initn: 2892 init1: 2892 opt: 2912 Z-score: 2190.3 bits: 414.3 E(85289): 2.9e-115 Smith-Waterman score: 2912; 99.8% identity (99.8% similar) in 425 aa overlap (1-425:1-424) 10 20 30 40 50 60 pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADKEA-FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP 360 370 380 390 400 410 pF1KB4 EGQGS ::::: NP_001 EGQGS 420 >>NP_001128728 (OMIM: 602923) histone-binding protein RB (390 aa) initn: 2698 init1: 2698 opt: 2698 Z-score: 2031.3 bits: 384.8 E(85289): 2.1e-106 Smith-Waterman score: 2698; 100.0% identity (100.0% similar) in 390 aa overlap (36-425:1-390) 10 20 30 40 50 60 pF1KB4 AAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHR :::::::::::::::::::::::::::::: NP_001 MTHALEWPSLTAQWLPDVTRPEGKDFSIHR 10 20 30 70 80 90 100 110 120 pF1KB4 LVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEG 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 EVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSW 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 NPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS 340 350 360 370 380 390 >>NP_002884 (OMIM: 300825) histone-binding protein RBBP7 (425 aa) initn: 2739 init1: 2592 opt: 2640 Z-score: 1987.7 bits: 376.8 E(85289): 5.6e-104 Smith-Waterman score: 2640; 89.2% identity (96.5% similar) in 426 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD ::.:: :.:.:::::::::::::::::::::::::::::.:::::.::::.::.::::: NP_002 MASKEM-FEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKD 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK ...: :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: ::: NP_002 YALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG ::::::::::::::::: ::::::::::::::::::::.::::::::::::::::::::: NP_002 INHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE :::::: ::::::::::::::.:::::.: :::::.::::.:::::.::::::.:::::: NP_002 YGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL ::::::::::::::::::::.:::::: :::::::::::::::::::::::::::::::: NP_002 SLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE :::::::::::.:::::::::::.::::::::::::::::::::::::::::::: :::: NP_002 WDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP ::::::::::::::::::::::::::::::::::::::::.:::::::::::. . ... NP_002 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSE 360 370 380 390 400 410 pF1KB4 -EGQGS ::::: NP_002 LEGQGS 420 >>NP_001185648 (OMIM: 300825) histone-binding protein RB (469 aa) initn: 2739 init1: 2592 opt: 2629 Z-score: 1979.1 bits: 375.4 E(85289): 1.7e-103 Smith-Waterman score: 2629; 89.7% identity (96.9% similar) in 419 aa overlap (8-425:51-469) 10 20 30 pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMT :.:.:::::::::::::::::::::::::: NP_001 QACGLLLHVHLSSRLGRAAPVRTGRHLRTVFEDTVEERVINEEYKIWKKNTPFLYDLVMT 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB4 HALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASH :::.:::::.::::.::.:::::...: :::::::::::::::.: :..::::::::::: NP_001 HALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASH 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB4 YDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKH ::.::::::::::.:::: :::::::::::::::::::: ::::::::::::::::::: NP_001 CDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKH 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB4 PSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVV :.::::::::::::::::::::::::::: ::::::::::::::.:::::.: :::::.: NP_001 PAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIV 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB4 DAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVN :::.:::::.::::::.::::::::::::::::::::::::::.:::::: ::::::::: NP_001 DAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVN 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB4 CLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSG ::::::::::::::::::::::::::::::::::.:::::::::::.::::::::::::: NP_001 CLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSG 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB4 TDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDN :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: NP_001 TDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDN 390 400 410 420 430 440 400 410 420 pF1KB4 IMQVWQMAENIYNDEDPEGSVDP-EGQGS :::.:::::::::::. . ... ::::: NP_001 IMQIWQMAENIYNDEESDVTTSELEGQGS 450 460 >>XP_011509771 (OMIM: 616620) PREDICTED: ribosome biogen (285 aa) initn: 370 init1: 195 opt: 265 Z-score: 221.4 bits: 49.4 E(85289): 1.4e-05 Smith-Waterman score: 278; 31.6% identity (64.4% similar) in 174 aa overlap (169-342:111-271) 140 150 160 170 180 190 pF1KB4 IIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASD : . : ::.. .. :. . .. ::: XP_011 VPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSD--AEEICSASW 90 100 110 120 130 200 210 220 230 240 250 pF1KB4 DHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTR :::: .::. . :.. :. .::. : . .:. : . : .: . :... .:: : XP_011 DHTIRVWDV----ESGSL---KSTLTGNK-VFNCISYSPLCKRL-ASGSTDRHIRLWDPR 140 150 160 170 180 260 270 280 290 300 310 pF1KB4 SNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKD ... : : :. .::. :. ....: : : .:: :. : ::: :. : :... .:.: XP_011 TKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHED 190 200 210 220 230 240 320 330 340 350 360 370 pF1KB4 EIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKIS ....:.:. . .: :.:.: .: XP_011 KVLSVDWT--DTGLLLSGGADNKLYSYRYSPTTSHVGA 250 260 270 280 >>NP_060726 (OMIM: 616620) ribosome biogenesis protein W (423 aa) initn: 370 init1: 195 opt: 265 Z-score: 219.4 bits: 49.6 E(85289): 1.7e-05 Smith-Waterman score: 278; 31.6% identity (64.4% similar) in 174 aa overlap (169-342:249-409) 140 150 160 170 180 190 pF1KB4 IIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASD : . : ::.. .. :. . .. ::: NP_060 VPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSD--AEEICSASW 220 230 240 250 260 270 200 210 220 230 240 250 pF1KB4 DHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTR :::: .::. . :.. :. .::. : . .:. : . : .: . :... .:: : NP_060 DHTIRVWDV----ESGSL---KSTLTGNK-VFNCISYSPLCKRL-ASGSTDRHIRLWDPR 280 290 300 310 320 260 270 280 290 300 310 pF1KB4 SNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKD ... : : :. .::. :. ....: : : .:: :. : ::: :. : :... .:.: NP_060 TKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHED 330 340 350 360 370 380 320 330 340 350 360 370 pF1KB4 EIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKIS ....:.:. . .: :.:.: .: NP_060 KVLSVDWT--DTGLLLSGGADNKLYSYRYSPTTSHVGA 390 400 410 420 >>XP_005267076 (OMIM: 215100,266500,601757,614879) PREDI (285 aa) initn: 361 init1: 177 opt: 251 Z-score: 211.0 bits: 47.5 E(85289): 5.2e-05 Smith-Waterman score: 306; 26.5% identity (54.7% similar) in 245 aa overlap (162-405:58-279) 140 150 160 170 180 190 pF1KB4 YMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSG : . .: . : .: :...:. . . XP_005 WNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGE 30 40 50 60 70 80 200 210 220 230 240 250 pF1KB4 HLL-SASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ .:. :.: :.:. ::: : :: . : :: ... .. : . :.:.. :: XP_005 QLVVSGSWDQTVKLWD----PTVGKSL---CTFRGHESIIYSTIWSPHIPGCFASASGDQ 90 100 110 120 130 140 260 270 280 290 300 310 pF1KB4 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL : :::... .. . :: ::. .. :.: .:.::..: .. :::::.. . XP_005 TLRIWDVKAAGVRI---VIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPV 150 160 170 180 190 320 330 340 350 360 370 pF1KB4 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH . .: : .:..:: . ..::: . : . :..:: : :: XP_005 FELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSK-------------PDSLLETV 200 210 220 230 240 380 390 400 410 420 pF1KB4 GGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS :: .... . : . . : :. ..... : XP_005 EHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA 250 260 270 280 >>NP_000279 (OMIM: 215100,266500,601757,614879) peroxiso (323 aa) initn: 361 init1: 177 opt: 251 Z-score: 210.3 bits: 47.6 E(85289): 5.6e-05 Smith-Waterman score: 306; 26.5% identity (54.7% similar) in 245 aa overlap (162-405:96-317) 140 150 160 170 180 190 pF1KB4 YMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSG : . .: . : .: :...:. . . NP_000 WNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGE 70 80 90 100 110 120 200 210 220 230 240 250 pF1KB4 HLL-SASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ .:. :.: :.:. ::: : :: . : :: ... .. : . :.:.. :: NP_000 QLVVSGSWDQTVKLWD----PTVGKSL---CTFRGHESIIYSTIWSPHIPGCFASASGDQ 130 140 150 160 170 260 270 280 290 300 310 pF1KB4 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL : :::... .. . :: ::. .. :.: .:.::..: .. :::::.. . NP_000 TLRIWDVKAAGVRI---VIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPV 180 190 200 210 220 230 320 330 340 350 360 370 pF1KB4 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH . .: : .:..:: . ..::: . : . :..:: : :: NP_000 FELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSK-------------PDSLLETV 240 250 260 270 280 380 390 400 410 420 pF1KB4 GGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS :: .... . : . . : :. ..... : NP_000 EHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA 290 300 310 320 >>NP_003301 (OMIM: 608998) protein TSSC1 isoform 2 [Homo (387 aa) initn: 240 init1: 95 opt: 242 Z-score: 202.8 bits: 46.4 E(85289): 0.00015 Smith-Waterman score: 266; 22.3% identity (51.3% similar) in 376 aa overlap (58-396:10-369) 30 40 50 60 70 80 pF1KB4 TPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLP : .:. . :. : .: :: ..: NP_003 MEDDAPVIYGLEFQARALTPQTAETDAIRFLV--GTQSL 10 20 30 90 100 110 120 130 140 pF1KB4 NDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIAT---KT . : :. .:.: .. :. .. ... ::. . : . ...: .: NP_003 KYDNQIHIIDFDDE----------NNIINKNVLLHQAGEIWHISASPADRGVLTTCYNRT 40 50 60 70 80 150 160 170 180 pF1KB4 PSSDVLV----------FDYTKHPSKPDPSGECNPDLRLRGH-QKEGYG----LSWNPNL .: ::. .. .: : :: :. :.: : .. ..: . :.: NP_003 SDSKVLTCAAVWRMPKELESGSHES-PDDSSSTAQTLELLCHLDNTAHGNMACVVWEPMG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB4 SGH-LLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVAD .:. ..: .:.: : :::.. ... .... .. . : :. ..:. NP_003 DGKKIISLADNH-ILLWDLQESSSQAVLASSASLEGKGQLKFTSGRWSPHHNCTQVATAN 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB4 DQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKL : : ::::: :. .:: : :.::: ... ::. . : : .:: ::. NP_003 DTTLRGWDTRS--MSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTE 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB4 KLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEE--------QSPEDAE ....: :. ...:... .. .. ....: :. . .. .:. : .. : : NP_003 PVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDISDQE 270 280 290 300 310 320 370 380 390 400 410 pF1KB4 DGPPE----------LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYN : : .. . : .. .:. .::.. :.: : NP_003 DHRSEEKSKEPLQDNVIATYEEHEDSVYAVDWSSADPWLFASLSYDGRLVINRVPRALKY 330 340 350 360 370 380 420 pF1KB4 DEDPEGSVDPEGQGS NP_003 HILL 425 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:55:10 2016 done: Fri Nov 4 22:55:11 2016 Total Scan time: 8.490 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]