Result of FASTA (omim) for
pF1KB4219
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4219, 941 aa
1>>>pF1KB4219 941 - 941 aa - 941 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6699+/-0.000351; mu= 16.0898+/- 0.022
mean_var=108.9795+/-21.423, 0's: 0 Z-trim(116.6): 210 B-trim: 57 in 1/60
Lambda= 0.122858
statistics sampled from 27749 (27959) to 27749 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.328), width: 16
Scan time: 12.540
The best scores are: opt bits E(85289)
NP_002590 (OMIM: 602658) cGMP-dependent 3',5'-cycl ( 941) 6310 1129.7 0
NP_001139681 (OMIM: 602658) cGMP-dependent 3',5'-c ( 932) 6134 1098.5 0
NP_001137311 (OMIM: 602658) cGMP-dependent 3',5'-c ( 934) 6132 1098.1 0
XP_005274097 (OMIM: 602658) PREDICTED: cGMP-depend ( 940) 5989 1072.8 0
NP_001230713 (OMIM: 602658) cGMP-dependent 3',5'-c ( 920) 5978 1070.8 0
XP_011543398 (OMIM: 602658) PREDICTED: cGMP-depend ( 620) 4170 750.3 7e-216
XP_016873399 (OMIM: 602658) PREDICTED: cGMP-depend ( 620) 4170 750.3 7e-216
NP_001070664 (OMIM: 604961,610475) dual 3',5'-cycl ( 489) 1037 194.9 8.5e-49
NP_001070826 (OMIM: 604961,610475) dual 3',5'-cycl ( 575) 1037 194.9 9.7e-49
NP_001070665 (OMIM: 604961,610475) dual 3',5'-cycl ( 683) 1037 195.0 1.1e-48
NP_058649 (OMIM: 604961,610475) dual 3',5'-cyclic- ( 933) 1037 195.1 1.4e-48
XP_016865685 (OMIM: 610652,616921,616922) PREDICTE ( 709) 752 144.5 1.8e-33
XP_016865684 (OMIM: 610652,616921,616922) PREDICTE ( 732) 752 144.5 1.9e-33
XP_006715384 (OMIM: 610652,616921,616922) PREDICTE ( 772) 752 144.5 2e-33
XP_011533690 (OMIM: 610652,616921,616922) PREDICTE ( 779) 752 144.5 2e-33
NP_006652 (OMIM: 610652,616921,616922) cAMP and cA ( 779) 752 144.5 2e-33
NP_001124162 (OMIM: 610652,616921,616922) cAMP and ( 789) 752 144.5 2e-33
XP_011533689 (OMIM: 610652,616921,616922) PREDICTE ( 831) 752 144.5 2.1e-33
XP_016865683 (OMIM: 610652,616921,616922) PREDICTE ( 800) 711 137.2 3.1e-31
XP_011533695 (OMIM: 610652,616921,616922) PREDICTE ( 466) 610 119.2 4.9e-26
XP_016865686 (OMIM: 610652,616921,616922) PREDICTE ( 631) 590 115.7 7.4e-25
NP_001001580 (OMIM: 602973) high affinity cGMP-spe ( 376) 526 104.2 1.3e-21
NP_001001576 (OMIM: 602973) high affinity cGMP-spe ( 376) 526 104.2 1.3e-21
NP_001001584 (OMIM: 602973) high affinity cGMP-spe ( 386) 526 104.3 1.3e-21
NP_001001572 (OMIM: 602973) high affinity cGMP-spe ( 386) 526 104.3 1.3e-21
NP_001001573 (OMIM: 602973) high affinity cGMP-spe ( 386) 526 104.3 1.3e-21
NP_001001585 (OMIM: 602973) high affinity cGMP-spe ( 386) 526 104.3 1.3e-21
XP_016883855 (OMIM: 602973) PREDICTED: high affini ( 386) 526 104.3 1.3e-21
NP_001001579 (OMIM: 602973) high affinity cGMP-spe ( 386) 526 104.3 1.3e-21
NP_001001575 (OMIM: 602973) high affinity cGMP-spe ( 433) 526 104.3 1.4e-21
NP_001001577 (OMIM: 602973) high affinity cGMP-spe ( 459) 526 104.3 1.5e-21
NP_001001569 (OMIM: 602973) high affinity cGMP-spe ( 465) 526 104.3 1.5e-21
NP_001001568 (OMIM: 602973) high affinity cGMP-spe ( 466) 526 104.3 1.5e-21
NP_001302462 (OMIM: 602973) high affinity cGMP-spe ( 485) 526 104.3 1.5e-21
NP_001001578 (OMIM: 602973) high affinity cGMP-spe ( 491) 526 104.3 1.6e-21
NP_001001571 (OMIM: 602973) high affinity cGMP-spe ( 492) 526 104.3 1.6e-21
NP_001001574 (OMIM: 602973) high affinity cGMP-spe ( 507) 526 104.3 1.6e-21
NP_001001581 (OMIM: 602973) high affinity cGMP-spe ( 526) 526 104.3 1.7e-21
NP_001001567 (OMIM: 602973) high affinity cGMP-spe ( 533) 526 104.3 1.7e-21
NP_001001570 (OMIM: 602973) high affinity cGMP-spe ( 540) 526 104.3 1.7e-21
XP_011527900 (OMIM: 602973) PREDICTED: high affini ( 545) 526 104.3 1.7e-21
NP_001001582 (OMIM: 602973) high affinity cGMP-spe ( 552) 526 104.3 1.7e-21
NP_001001583 (OMIM: 602973) high affinity cGMP-spe ( 567) 526 104.4 1.8e-21
NP_002597 (OMIM: 602973) high affinity cGMP-specif ( 593) 526 104.4 1.8e-21
XP_011526360 (OMIM: 600128) PREDICTED: cAMP-specif ( 481) 520 103.2 3.2e-21
XP_011526358 (OMIM: 600128) PREDICTED: cAMP-specif ( 606) 520 103.3 3.9e-21
NP_001092289 (OMIM: 600128) cAMP-specific 3',5'-cy ( 606) 520 103.3 3.9e-21
NP_001092288 (OMIM: 600128) cAMP-specific 3',5'-cy ( 680) 520 103.3 4.3e-21
NP_001317101 (OMIM: 600128) cAMP-specific 3',5'-cy ( 712) 520 103.3 4.4e-21
NP_000914 (OMIM: 600128) cAMP-specific 3',5'-cycli ( 712) 520 103.3 4.4e-21
>>NP_002590 (OMIM: 602658) cGMP-dependent 3',5'-cyclic p (941 aa)
initn: 6310 init1: 6310 opt: 6310 Z-score: 6044.0 bits: 1129.7 E(85289): 0
Smith-Waterman score: 6310; 100.0% identity (100.0% similar) in 941 aa overlap (1-941:1-941)
10 20 30 40 50 60
pF1KB4 MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 QKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
850 860 870 880 890 900
910 920 930 940
pF1KB4 KFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
:::::::::::::::::::::::::::::::::::::::::
NP_002 KFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
910 920 930 940
>>NP_001139681 (OMIM: 602658) cGMP-dependent 3',5'-cycli (932 aa)
initn: 6134 init1: 6134 opt: 6134 Z-score: 5875.5 bits: 1098.5 E(85289): 0
Smith-Waterman score: 6134; 99.8% identity (99.9% similar) in 920 aa overlap (22-941:13-932)
10 20 30 40 50 60
pF1KB4 MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDI
:. ::::::::::::::::::::::::::::::::::::
NP_001 MKKQRIQEGKSLAHRRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDI
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 SGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 GLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 EKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 DASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB4 ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB4 AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB4 SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB4 ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 QKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB4 GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
840 850 860 870 880 890
910 920 930 940
pF1KB4 KFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
:::::::::::::::::::::::::::::::::::::::::
NP_001 KFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
900 910 920 930
>>NP_001137311 (OMIM: 602658) cGMP-dependent 3',5'-cycli (934 aa)
initn: 6132 init1: 6132 opt: 6132 Z-score: 5873.5 bits: 1098.1 E(85289): 0
Smith-Waterman score: 6132; 100.0% identity (100.0% similar) in 917 aa overlap (25-941:18-934)
10 20 30 40 50 60
pF1KB4 MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDI
::::::::::::::::::::::::::::::::::::
NP_001 MVLVLHHILIAVVQFLRRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDI
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 SGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 GLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 EKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 DASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB4 ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPD
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB4 AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB4 SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB4 ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 QKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB4 GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
840 850 860 870 880 890
910 920 930 940
pF1KB4 KFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
:::::::::::::::::::::::::::::::::::::::::
NP_001 KFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
900 910 920 930
>>XP_005274097 (OMIM: 602658) PREDICTED: cGMP-dependent (940 aa)
initn: 5978 init1: 5978 opt: 5989 Z-score: 5736.5 bits: 1072.8 E(85289): 0
Smith-Waterman score: 5989; 98.4% identity (98.7% similar) in 917 aa overlap (26-941:24-940)
10 20 30 40 50
pF1KB4 MGQACGHSILCRSQQYPAARPAEPRGQQVFLKP-DEPPPPPQPCADSLQDALLSLGSVID
: :. : : . : :: : :.:::::::::::
XP_005 MPPIHGCLYWGLPLGDRKGMGVSGAQASLDPLAKEPGPPGSRDDRLEDALLSLGSVID
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 ISGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISGLQRAVKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 NGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGLGFSDLPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 VEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEKHTLVALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 LDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 VEDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFT
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 DEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIIT
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB4 EARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIP
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB4 DAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATA
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB4 FSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSN
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB4 FASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWM
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB4 HAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALY
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB4 SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKD
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB4 LQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKA
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB4 MGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVS
840 850 860 870 880 890
900 910 920 930 940
pF1KB4 HKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
::::::::::::::::::::::::::::::::::::::::::
XP_005 HKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
900 910 920 930 940
>>NP_001230713 (OMIM: 602658) cGMP-dependent 3',5'-cycli (920 aa)
initn: 5978 init1: 5978 opt: 5978 Z-score: 5726.1 bits: 1070.8 E(85289): 0
Smith-Waterman score: 5978; 99.2% identity (99.3% similar) in 905 aa overlap (37-941:16-920)
10 20 30 40 50 60
pF1KB4 HSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPPQPCADSLQDALLSLGSVIDISGLQRA
: :: : :.::::::::::::::::::
NP_001 MRRQPAASLDPLAKEPGPPGSRDDRLEDALLSLGSVIDISGLQRA
10 20 30 40
70 80 90 100 110 120
pF1KB4 VKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKEALSAVLPRVETVYTYLLDGESQLVCEDPPHELPQEGKVREAIISQKRLGCNGLGFSD
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 LPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPGKPLARLVAPLAPDTQVLVMPLADKEAGAVAAVILVHCGQLSDNEEWSLQAVEKHTLV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB4 ALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALRRVQVLQQRGPREAPRAVQNPPEGTAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQ
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB4 LKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB4 QLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVI
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB4 QHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSN
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB4 AEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPL
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB4 FYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGI
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB4 SIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB4 PRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSH
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB4 FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVM
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB4 ERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEV
710 720 730 740 750 760
790 800 810 820 830 840
pF1KB4 GYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPME
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB4 MMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRG
830 840 850 860 870 880
910 920 930 940
pF1KB4 LPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
:::::::::::::::::::::::::::::::::::
NP_001 LPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
890 900 910 920
>>XP_011543398 (OMIM: 602658) PREDICTED: cGMP-dependent (620 aa)
initn: 4170 init1: 4170 opt: 4170 Z-score: 3996.7 bits: 750.3 E(85289): 7e-216
Smith-Waterman score: 4170; 100.0% identity (100.0% similar) in 620 aa overlap (322-941:1-620)
300 310 320 330 340 350
pF1KB4 LTGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFN
::::::::::::::::::::::::::::::
XP_011 MLGCELQAMLCVPVISRATDQVVALACAFN
10 20 30
360 370 380 390 400 410
pF1KB4 KLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVS
40 50 60 70 80 90
420 430 440 450 460 470
pF1KB4 VLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVAT
100 110 120 130 140 150
480 490 500 510 520 530
pF1KB4 TGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSK
160 170 180 190 200 210
540 550 560 570 580 590
pF1KB4 FDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQ
220 230 240 250 260 270
600 610 620 630 640 650
pF1KB4 PVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYR
280 290 300 310 320 330
660 670 680 690 700 710
pF1KB4 DPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVAS
340 350 360 370 380 390
720 730 740 750 760 770
pF1KB4 KSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLA
400 410 420 430 440 450
780 790 800 810 820 830
pF1KB4 HHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFF
460 470 480 490 500 510
840 850 860 870 880 890
pF1KB4 SQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASN
520 530 540 550 560 570
900 910 920 930 940
pF1KB4 REHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
580 590 600 610 620
>>XP_016873399 (OMIM: 602658) PREDICTED: cGMP-dependent (620 aa)
initn: 4170 init1: 4170 opt: 4170 Z-score: 3996.7 bits: 750.3 E(85289): 7e-216
Smith-Waterman score: 4170; 100.0% identity (100.0% similar) in 620 aa overlap (322-941:1-620)
300 310 320 330 340 350
pF1KB4 LTGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFN
::::::::::::::::::::::::::::::
XP_016 MLGCELQAMLCVPVISRATDQVVALACAFN
10 20 30
360 370 380 390 400 410
pF1KB4 KLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVS
40 50 60 70 80 90
420 430 440 450 460 470
pF1KB4 VLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVAT
100 110 120 130 140 150
480 490 500 510 520 530
pF1KB4 TGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSK
160 170 180 190 200 210
540 550 560 570 580 590
pF1KB4 FDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQ
220 230 240 250 260 270
600 610 620 630 640 650
pF1KB4 PVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYR
280 290 300 310 320 330
660 670 680 690 700 710
pF1KB4 DPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVAS
340 350 360 370 380 390
720 730 740 750 760 770
pF1KB4 KSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLA
400 410 420 430 440 450
780 790 800 810 820 830
pF1KB4 HHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFF
460 470 480 490 500 510
840 850 860 870 880 890
pF1KB4 SQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASN
520 530 540 550 560 570
900 910 920 930 940
pF1KB4 REHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
580 590 600 610 620
>>NP_001070664 (OMIM: 604961,610475) dual 3',5'-cyclic-A (489 aa)
initn: 900 init1: 460 opt: 1037 Z-score: 997.1 bits: 194.9 E(85289): 8.5e-49
Smith-Waterman score: 1037; 37.1% identity (68.9% similar) in 456 aa overlap (462-911:28-477)
440 450 460 470 480 490
pF1KB4 VFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGV
...:: ::.:: .:: ::: : : .
NP_001 MSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEA
10 20 30 40 50
500 510 520 530 540 550
pF1KB4 DDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHS
:. .::. :..:: :: : :...::::...:...: :. :. : :: :.::..: ..
NP_001 DQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNT
60 70 80 90 100 110
560 570 580 590 600
pF1KB4 LLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVA--AIDS-NFASFTYTPR
..: .:... .. .: ... :: : : :. .: :. :::. .: .:
NP_001 IMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDF-----
120 130 140 150 160 170
610 620 630 640 650 660
pF1KB4 SLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFC
:: : : : :..........::: :: :. : :.:.:: :::: :::.: ..
NP_001 SLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLM
180 190 200 210 220 230
670 680 690 700 710 720
pF1KB4 YLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMER
. . . . . : ..::.:....:.:::::::::::.::. : :.:: ::.. .. .:.
NP_001 FAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSAT-LEH
240 250 260 270 280 290
730 740 750 760 770 780
pF1KB4 HHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG-
::: .:. ::...: ::: ..: :.:. ...:... ::::::. ... .. ... :
NP_001 HHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGE
300 310 320 330 340 350
790 800 810 820 830 840
pF1KB4 YDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEK-AMGNRPME
:: : :.:. .. .:::.:::. :: :. .:..:::. .::: ::: :. . :
NP_001 YDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSA
360 370 380 390 400 410
850 860 870 880 890 900
pF1KB4 MMDRE-KAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIR
..::. : .:.::. ... : ::.:. : . : . . ::.:: .: .. .: .
NP_001 IFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLA
420 430 440 450 460 470
910 920 930 940
pF1KB4 GLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
. :..
NP_001 STASSSPASVMVAKEDRN
480
>>NP_001070826 (OMIM: 604961,610475) dual 3',5'-cyclic-A (575 aa)
initn: 983 init1: 460 opt: 1037 Z-score: 996.0 bits: 194.9 E(85289): 9.7e-49
Smith-Waterman score: 1097; 34.6% identity (66.3% similar) in 569 aa overlap (366-911:1-563)
340 350 360 370 380 390
pF1KB4 ISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQA
.: . . . ..... : .: . .:
NP_001 MQMYLPFCGIAISNAQLFAASRKEYERSRA
10 20 30
400 410 420 430 440
pF1KB4 LLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNE--LV--AKVF------
::.:...:: . :. ....:. .:..: . : :::.::.. : .: .: :
NP_001 LLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPK
40 50 60 70 80 90
450 460 470 480 490
pF1KB4 ---DGGVVDDESYEIRIPAD----QGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFR
:. ::.: .: ..:: ::.:: .:: ::: : : .:. .::.
NP_001 CSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFH
100 110 120 130 140 150
500 510 520 530 540 550
pF1KB4 TRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVN
:..:: :: : :...::::...:...: :. :. : :: :.::..: ....: .:.
NP_001 IRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVK
160 170 180 190 200 210
560 570 580 590 600 610
pF1KB4 EAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVA--AIDS-NFASFTYTPRSLPEDDT
.. .. .: ... :: : : :. .: :. :::. .: .: :: :
NP_001 KSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDF-----SLDVDAM
220 230 240 250 260
620 630 640 650 660 670
pF1KB4 SMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNL
: : :..........::: :: :. : :.:.:: :::: :::.: .. . . .
NP_001 ITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTA
270 280 290 300 310 320
680 690 700 710 720 730
pF1KB4 ELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAI
. . : ..::.:....:.:::::::::::.::. : :.:: ::.. ....:.::: .:.
NP_001 GFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGT-SATLEHHHFNHAV
330 340 350 360 370 380
740 750 760 770 780 790
pF1KB4 AILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG-YDRNNKQ
::...: ::: ..: :.:. ...:... ::::::. ... .. ... : :: : :.
NP_001 MILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKN
390 400 410 420 430 440
800 810 820 830 840 850
pF1KB4 HHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEK-AMGNRPMEMMDRE-K
:. .. .:::.:::. :: :. .:..:::. .::: ::: :. . : ..::. :
NP_001 HRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRK
450 460 470 480 490 500
860 870 880 890 900 910
pF1KB4 AYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNS
.:.::. ... : ::.:. : . : . . ::.:: .: .. .: . . :..
NP_001 DELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLASTASSSP
510 520 530 540 550 560
920 930 940
pF1KB4 LDFLDEEYEVPDLDGTRAPINGCCSLDAE
NP_001 ASVMVAKEDRN
570
>>NP_001070665 (OMIM: 604961,610475) dual 3',5'-cyclic-A (683 aa)
initn: 1050 init1: 460 opt: 1037 Z-score: 994.9 bits: 195.0 E(85289): 1.1e-48
Smith-Waterman score: 1210; 34.1% identity (66.7% similar) in 634 aa overlap (303-911:48-671)
280 290 300 310 320 330
pF1KB4 QLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGCELQAMLC
... . :: .: ..... : . ...::
NP_001 QWKKVKITRLVQISGASLAEKQEKHQDFLIQRQTKTKDRRFND--EIDKLTGYKTKSLLC
20 30 40 50 60 70
340 350 360 370 380 390
pF1KB4 VPVISRATD-QVVALACAFNKL-EGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLK
.:. :..: .....: :.::. :: ::..::.:.: . . . ..... : .:
NP_001 MPI--RSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEY
80 90 100 110 120 130
400 410 420 430 440
pF1KB4 CECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNEL----VAKVF-
. .:::.:...:: . :. ....:. .:..: . : :::.::.. : .: :
NP_001 ERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFE
140 150 160 170 180 190
450 460 470 480 490
pF1KB4 --------DGGVVDDESYEIRIPAD----QGIAGHVATTGQILNIPDAYAHPLFYRGVDD
:. ::.: .: ..:: ::.:: .:: ::: : : .:.
NP_001 LMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQ
200 210 220 230 240 250
500 510 520 530 540 550
pF1KB4 STGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLL
.::. :..:: :: : :...::::...:...: :. :. : :: :.::..: ....
NP_001 ISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIM
260 270 280 290 300 310
560 570 580 590 600 610
pF1KB4 YKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVA--AIDS-NFASFTYTPRSL
: .:... .. .: ... :: : : :. .: :. :::. .: .: ::
NP_001 YDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDF-----SL
320 330 340 350 360
620 630 640 650 660 670
pF1KB4 PEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYL
: : : :..........::: :: :. : :.:.:: :::: :::.: .. .
NP_001 DVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFA
370 380 390 400 410 420
680 690 700 710 720 730
pF1KB4 LYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHH
. . . . : ..::.:....:.:::::::::::.::. : :.:: ::.. ....:.::
NP_001 MLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGT-SATLEHHH
430 440 450 460 470 480
740 750 760 770 780
pF1KB4 FAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVG-YD
: .:. ::...: ::: ..: :.:. ...:... ::::::. ... .. ... : ::
NP_001 FNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYD
490 500 510 520 530 540
790 800 810 820 830 840
pF1KB4 RNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEK-AMGNRPMEMM
: :.:. .. .:::.:::. :: :. .:..:::. .::: ::: :. . : ..
NP_001 WNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIF
550 560 570 580 590 600
850 860 870 880 890 900
pF1KB4 DRE-KAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGL
::. : .:.::. ... : ::.:. : . : . . ::.:: .: .. .: . .
NP_001 DRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQKRLLAST
610 620 630 640 650 660
910 920 930 940
pF1KB4 PSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDAE
:..
NP_001 ASSSPASVMVAKEDRN
670 680
941 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:37:10 2016 done: Thu Nov 3 14:37:12 2016
Total Scan time: 12.540 Total Display time: 0.320
Function used was FASTA [36.3.4 Apr, 2011]