Result of FASTA (omim) for
pF1KB4182
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4182, 356 aa
1>>>pF1KB4182 356 - 356 aa - 356 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6237+/-0.000314; mu= 7.4660+/- 0.020
mean_var=158.6239+/-31.960, 0's: 0 Z-trim(121.2): 15 B-trim: 700 in 1/58
Lambda= 0.101833
statistics sampled from 37428 (37443) to 37428 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.439), width: 16
Scan time: 10.080
The best scores are: opt bits E(85289)
NP_036253 (OMIM: 605468) cdc42 effector protein 4 ( 356) 2351 356.7 4.6e-98
XP_005257239 (OMIM: 605468) PREDICTED: cdc42 effec ( 356) 2351 356.7 4.6e-98
XP_006724171 (OMIM: 606084) PREDICTED: cdc42 effec ( 391) 265 50.3 8.8e-06
XP_016884030 (OMIM: 606084) PREDICTED: cdc42 effec ( 391) 265 50.3 8.8e-06
XP_006724172 (OMIM: 606084) PREDICTED: cdc42 effec ( 391) 265 50.3 8.8e-06
XP_006724170 (OMIM: 606084) PREDICTED: cdc42 effec ( 391) 265 50.3 8.8e-06
NP_689449 (OMIM: 606084) cdc42 effector protein 1 ( 391) 265 50.3 8.8e-06
NP_659494 (OMIM: 609171) cdc42 effector protein 5 ( 148) 228 44.5 0.00018
>>NP_036253 (OMIM: 605468) cdc42 effector protein 4 [Hom (356 aa)
initn: 2351 init1: 2351 opt: 2351 Z-score: 1881.6 bits: 356.7 E(85289): 4.6e-98
Smith-Waterman score: 2351; 100.0% identity (100.0% similar) in 356 aa overlap (1-356:1-356)
10 20 30 40 50 60
pF1KB4 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTEEAVPRRNGAAGPHSPDPLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTEEAVPRRNGAAGPHSPDPLLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSMLGDVLSIMDKEEWDPEEGEGGYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSMLGDVLSIMDKEEWDPEEGEGGYH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPSHALEDEGWAAAAPSPGSARSMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPSHALEDEGWAAAAPSPGSARSMG
250 260 270 280 290 300
310 320 330 340 350
pF1KB4 SHTTRDSSSLSSCTSGILEERSPAFRGPDRARAAVSRQPDKEFSFMDEEEEDEIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SHTTRDSSSLSSCTSGILEERSPAFRGPDRARAAVSRQPDKEFSFMDEEEEDEIRV
310 320 330 340 350
>>XP_005257239 (OMIM: 605468) PREDICTED: cdc42 effector (356 aa)
initn: 2351 init1: 2351 opt: 2351 Z-score: 1881.6 bits: 356.7 E(85289): 4.6e-98
Smith-Waterman score: 2351; 100.0% identity (100.0% similar) in 356 aa overlap (1-356:1-356)
10 20 30 40 50 60
pF1KB4 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 QLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTEEAVPRRNGAAGPHSPDPLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTEEAVPRRNGAAGPHSPDPLLD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSMLGDVLSIMDKEEWDPEEGEGGYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSMLGDVLSIMDKEEWDPEEGEGGYH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 GDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPSHALEDEGWAAAAPSPGSARSMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPSHALEDEGWAAAAPSPGSARSMG
250 260 270 280 290 300
310 320 330 340 350
pF1KB4 SHTTRDSSSLSSCTSGILEERSPAFRGPDRARAAVSRQPDKEFSFMDEEEEDEIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHTTRDSSSLSSCTSGILEERSPAFRGPDRARAAVSRQPDKEFSFMDEEEEDEIRV
310 320 330 340 350
>>XP_006724171 (OMIM: 606084) PREDICTED: cdc42 effector (391 aa)
initn: 321 init1: 207 opt: 265 Z-score: 224.8 bits: 50.3 E(85289): 8.8e-06
Smith-Waterman score: 395; 33.3% identity (56.0% similar) in 327 aa overlap (10-328:25-309)
10 20 30 40
pF1KB4 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGD
:: ..::: :::.::: :::::::::::::.::
XP_006 MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR----LTADMISHPLGDFRHTMHVGRGGD
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 AFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGS
.:::::::....: . :. : ::.:..:.. .: . : : :
XP_006 VFGDTSFLSNHGGS--------SGSTHRSPRSFLAKKLQLVRRVGAPPR--RMASPPAPS
60 70 80 90 100
110 120 130 140 150 160
pF1KB4 LRDSAL--FVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGE---GGDEEAGTE
:. ..:::.::::::. ..:: :..:::.. ..::. : : :
XP_006 PAPPAISPIIKNAISLPQLNQAAYDSLVVGKL--SFDSSPTS-STDGHSSYGLDSGFCTI
110 120 130 140 150 160
170 180 190 200 210
pF1KB4 EAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDL--GPSML
.:: . ::. : . .: : : ::....:..::..:: :::.:
XP_006 SRLPR---SEKPHDRD---RDGSF------PSEP----GLRRSDSLLSFRLDLDLGPSLL
170 180 190 200
220 230 240 250 260 270
pF1KB4 GDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPS
...:..:. :: . . . . : : .: :: . . : :: :
XP_006 SELLGVMSL----PEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAP-
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB4 HALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERS-PAFRGPDRARAAVSR
: : :: :.:... . .: ..... . . : .: :. ::
XP_006 -AATPTGPAANPPAPAASSTPHGHCP---NGVTAGLGPVAEVKSSPVGGGPRGPAGPALG
270 280 290 300 310
340 350
pF1KB4 QPDKEFSFMDEEEEDEIRV
XP_006 RHWGAGWDGGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTF
320 330 340 350 360 370
>>XP_016884030 (OMIM: 606084) PREDICTED: cdc42 effector (391 aa)
initn: 321 init1: 207 opt: 265 Z-score: 224.8 bits: 50.3 E(85289): 8.8e-06
Smith-Waterman score: 395; 33.3% identity (56.0% similar) in 327 aa overlap (10-328:25-309)
10 20 30 40
pF1KB4 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGD
:: ..::: :::.::: :::::::::::::.::
XP_016 MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR----LTADMISHPLGDFRHTMHVGRGGD
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 AFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGS
.:::::::....: . :. : ::.:..:.. .: . : : :
XP_016 VFGDTSFLSNHGGS--------SGSTHRSPRSFLAKKLQLVRRVGAPPR--RMASPPAPS
60 70 80 90 100
110 120 130 140 150 160
pF1KB4 LRDSAL--FVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGE---GGDEEAGTE
:. ..:::.::::::. ..:: :..:::.. ..::. : : :
XP_016 PAPPAISPIIKNAISLPQLNQAAYDSLVVGKL--SFDSSPTS-STDGHSSYGLDSGFCTI
110 120 130 140 150 160
170 180 190 200 210
pF1KB4 EAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDL--GPSML
.:: . ::. : . .: : : ::....:..::..:: :::.:
XP_016 SRLPR---SEKPHDRD---RDGSF------PSEP----GLRRSDSLLSFRLDLDLGPSLL
170 180 190 200
220 230 240 250 260 270
pF1KB4 GDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPS
...:..:. :: . . . . : : .: :: . . : :: :
XP_016 SELLGVMSL----PEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAP-
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB4 HALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERS-PAFRGPDRARAAVSR
: : :: :.:... . .: ..... . . : .: :. ::
XP_016 -AATPTGPAANPPAPAASSTPHGHCP---NGVTAGLGPVAEVKSSPVGGGPRGPAGPALG
270 280 290 300 310
340 350
pF1KB4 QPDKEFSFMDEEEEDEIRV
XP_016 RHWGAGWDGGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTF
320 330 340 350 360 370
>>XP_006724172 (OMIM: 606084) PREDICTED: cdc42 effector (391 aa)
initn: 321 init1: 207 opt: 265 Z-score: 224.8 bits: 50.3 E(85289): 8.8e-06
Smith-Waterman score: 395; 33.3% identity (56.0% similar) in 327 aa overlap (10-328:25-309)
10 20 30 40
pF1KB4 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGD
:: ..::: :::.::: :::::::::::::.::
XP_006 MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR----LTADMISHPLGDFRHTMHVGRGGD
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 AFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGS
.:::::::....: . :. : ::.:..:.. .: . : : :
XP_006 VFGDTSFLSNHGGS--------SGSTHRSPRSFLAKKLQLVRRVGAPPR--RMASPPAPS
60 70 80 90 100
110 120 130 140 150 160
pF1KB4 LRDSAL--FVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGE---GGDEEAGTE
:. ..:::.::::::. ..:: :..:::.. ..::. : : :
XP_006 PAPPAISPIIKNAISLPQLNQAAYDSLVVGKL--SFDSSPTS-STDGHSSYGLDSGFCTI
110 120 130 140 150 160
170 180 190 200 210
pF1KB4 EAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDL--GPSML
.:: . ::. : . .: : : ::....:..::..:: :::.:
XP_006 SRLPR---SEKPHDRD---RDGSF------PSEP----GLRRSDSLLSFRLDLDLGPSLL
170 180 190 200
220 230 240 250 260 270
pF1KB4 GDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPS
...:..:. :: . . . . : : .: :: . . : :: :
XP_006 SELLGVMSL----PEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAP-
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB4 HALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERS-PAFRGPDRARAAVSR
: : :: :.:... . .: ..... . . : .: :. ::
XP_006 -AATPTGPAANPPAPAASSTPHGHCP---NGVTAGLGPVAEVKSSPVGGGPRGPAGPALG
270 280 290 300 310
340 350
pF1KB4 QPDKEFSFMDEEEEDEIRV
XP_006 RHWGAGWDGGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTF
320 330 340 350 360 370
>>XP_006724170 (OMIM: 606084) PREDICTED: cdc42 effector (391 aa)
initn: 321 init1: 207 opt: 265 Z-score: 224.8 bits: 50.3 E(85289): 8.8e-06
Smith-Waterman score: 395; 33.3% identity (56.0% similar) in 327 aa overlap (10-328:25-309)
10 20 30 40
pF1KB4 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGD
:: ..::: :::.::: :::::::::::::.::
XP_006 MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR----LTADMISHPLGDFRHTMHVGRGGD
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 AFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGS
.:::::::....: . :. : ::.:..:.. .: . : : :
XP_006 VFGDTSFLSNHGGS--------SGSTHRSPRSFLAKKLQLVRRVGAPPR--RMASPPAPS
60 70 80 90 100
110 120 130 140 150 160
pF1KB4 LRDSAL--FVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGE---GGDEEAGTE
:. ..:::.::::::. ..:: :..:::.. ..::. : : :
XP_006 PAPPAISPIIKNAISLPQLNQAAYDSLVVGKL--SFDSSPTS-STDGHSSYGLDSGFCTI
110 120 130 140 150 160
170 180 190 200 210
pF1KB4 EAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDL--GPSML
.:: . ::. : . .: : : ::....:..::..:: :::.:
XP_006 SRLPR---SEKPHDRD---RDGSF------PSEP----GLRRSDSLLSFRLDLDLGPSLL
170 180 190 200
220 230 240 250 260 270
pF1KB4 GDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPS
...:..:. :: . . . . : : .: :: . . : :: :
XP_006 SELLGVMSL----PEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAP-
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB4 HALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERS-PAFRGPDRARAAVSR
: : :: :.:... . .: ..... . . : .: :. ::
XP_006 -AATPTGPAANPPAPAASSTPHGHCP---NGVTAGLGPVAEVKSSPVGGGPRGPAGPALG
270 280 290 300 310
340 350
pF1KB4 QPDKEFSFMDEEEEDEIRV
XP_006 RHWGAGWDGGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTF
320 330 340 350 360 370
>>NP_689449 (OMIM: 606084) cdc42 effector protein 1 [Hom (391 aa)
initn: 321 init1: 207 opt: 265 Z-score: 224.8 bits: 50.3 E(85289): 8.8e-06
Smith-Waterman score: 395; 33.3% identity (56.0% similar) in 327 aa overlap (10-328:25-309)
10 20 30 40
pF1KB4 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGD
:: ..::: :::.::: :::::::::::::.::
NP_689 MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR----LTADMISHPLGDFRHTMHVGRGGD
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 AFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGS
.:::::::....: . :. : ::.:..:.. .: . : : :
NP_689 VFGDTSFLSNHGGS--------SGSTHRSPRSFLAKKLQLVRRVGAPPR--RMASPPAPS
60 70 80 90 100
110 120 130 140 150 160
pF1KB4 LRDSAL--FVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGE---GGDEEAGTE
:. ..:::.::::::. ..:: :..:::.. ..::. : : :
NP_689 PAPPAISPIIKNAISLPQLNQAAYDSLVVGKL--SFDSSPTS-STDGHSSYGLDSGFCTI
110 120 130 140 150 160
170 180 190 200 210
pF1KB4 EAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDL--GPSML
.:: . ::. : . .: : : ::....:..::..:: :::.:
NP_689 SRLPR---SEKPHDRD---RDGSF------PSEP----GLRRSDSLLSFRLDLDLGPSLL
170 180 190 200
220 230 240 250 260 270
pF1KB4 GDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSLPS
...:..:. :: . . . . : : .: :: . . : :: :
NP_689 SELLGVMSL----PEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAP-
210 220 230 240 250 260
280 290 300 310 320 330
pF1KB4 HALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERS-PAFRGPDRARAAVSR
: : :: :.:... . .: ..... . . : .: :. ::
NP_689 -AATPTGPAANPPAPAASSTPHGHCP---NGVTAGLGPVAEVKSSPVGGGPRGPAGPALG
270 280 290 300 310
340 350
pF1KB4 QPDKEFSFMDEEEEDEIRV
NP_689 RHWGAGWDGGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTF
320 330 340 350 360 370
>>NP_659494 (OMIM: 609171) cdc42 effector protein 5 [Hom (148 aa)
initn: 350 init1: 195 opt: 228 Z-score: 201.3 bits: 44.5 E(85289): 0.00018
Smith-Waterman score: 228; 58.7% identity (74.6% similar) in 63 aa overlap (1-63:1-59)
10 20 30 40 50 60
pF1KB4 MPILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAGDAFGDTSFLNSKAGEP
::.:::: . . ..: : : :::::::::::.::::.::::::::::. ..: :
NP_659 MPVLKQLGPA----QPKKRPDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGP
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 DGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDMLGSLRDSALFVKNAMSLP
:
NP_659 PPEPRAPPAGAPRSPPPPAVPQSAAPSPADPLLSFHLDLGPSMLDAVLGVMDAARPEAAA
60 70 80 90 100 110
356 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:53:08 2016 done: Fri Nov 4 02:53:10 2016
Total Scan time: 10.080 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]