FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4084, 969 aa 1>>>pF1KB4084 969 - 969 aa - 969 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6298+/-0.00101; mu= 15.7973+/- 0.061 mean_var=102.3275+/-20.422, 0's: 0 Z-trim(107.0): 22 B-trim: 0 in 0/49 Lambda= 0.126788 statistics sampled from 9291 (9302) to 9291 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.286), width: 16 Scan time: 4.560 The best scores are: opt bits E(32554) CCDS7072.1 FBXO18 gene_id:84893|Hs108|chr10 (1043) 6499 1200.0 0 CCDS7073.1 FBXO18 gene_id:84893|Hs108|chr10 (1094) 6499 1200.1 0 CCDS73064.1 FBXO18 gene_id:84893|Hs108|chr10 ( 986) 5341 988.2 0 >>CCDS7072.1 FBXO18 gene_id:84893|Hs108|chr10 (1043 aa) initn: 6499 init1: 6499 opt: 6499 Z-score: 6423.3 bits: 1200.0 E(32554): 0 Smith-Waterman score: 6499; 100.0% identity (100.0% similar) in 969 aa overlap (1-969:75-1043) 10 20 30 pF1KB4 MAKSNSVGQDSCQDSEGDMIFPAESSCALP :::::::::::::::::::::::::::::: CCDS70 PRTKRGSRGQGSQRCIPEFFLAGKQPCTNDMAKSNSVGQDSCQDSEGDMIFPAESSCALP 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB4 QEGSAGPGSPGSAPPSRKRSWSSEEESNQATGTSRWDGVSKKAPRHHLSVPCTRPREARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 QEGSAGPGSPGSAPPSRKRSWSSEEESNQATGTSRWDGVSKKAPRHHLSVPCTRPREARQ 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB4 EAEDSTSRLSAESGETDQDAGDVGPDPIPDSYYGLLGTLPCQEALSHICSLPSEVLRHVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 EAEDSTSRLSAESGETDQDAGDVGPDPIPDSYYGLLGTLPCQEALSHICSLPSEVLRHVF 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB4 AFLPVEDLYWNLSLVCHLWREIISDPLFIPWKKLYHRYLMNEEQAVSKVDGILSNCGIEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 AFLPVEDLYWNLSLVCHLWREIISDPLFIPWKKLYHRYLMNEEQAVSKVDGILSNCGIEK 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB4 ESDLCVLNLIRYTATTKCSPSVDPERVLWSLRDHPLLPEAEACVRQHLPDLYAAAGGVNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 ESDLCVLNLIRYTATTKCSPSVDPERVLWSLRDHPLLPEAEACVRQHLPDLYAAAGGVNI 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB4 WALVAAVVLLSSSVNDIQRLLFCLRRPSSTVTMPDVTETLYCIAVLLYAMREKGINISNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 WALVAAVVLLSSSVNDIQRLLFCLRRPSSTVTMPDVTETLYCIAVLLYAMREKGINISNR 350 360 370 380 390 400 340 350 360 370 380 390 pF1KB4 IHYNIFYCLYLQENSCTQATKVKEEPSVWPGKKTIQLTHEQQLILNHKMEPLQVVKIMAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 IHYNIFYCLYLQENSCTQATKVKEEPSVWPGKKTIQLTHEQQLILNHKMEPLQVVKIMAF 410 420 430 440 450 460 400 410 420 430 440 450 pF1KB4 AGTGKTSTLVKYAEKWSQSRFLYVTFNKSIAKQAERVFPSNVICKTFHSMAYGHIGRKYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 AGTGKTSTLVKYAEKWSQSRFLYVTFNKSIAKQAERVFPSNVICKTFHSMAYGHIGRKYQ 470 480 490 500 510 520 460 470 480 490 500 510 pF1KB4 SKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 SKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSQ 530 540 550 560 570 580 520 530 540 550 560 570 pF1KB4 GQRVMVEQSEKLNGVLEASRLWDNMRKLGECTEEAHQMTHDGYLKLWQLSKPSLASFDAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 GQRVMVEQSEKLNGVLEASRLWDNMRKLGECTEEAHQMTHDGYLKLWQLSKPSLASFDAI 590 600 610 620 630 640 580 590 600 610 620 630 pF1KB4 FVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQQIYTFRGAVNALFTVPHTHVFYLTQSFRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 FVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQQIYTFRGAVNALFTVPHTHVFYLTQSFRF 650 660 670 680 690 700 640 650 660 670 680 690 pF1KB4 GVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGDAKGQVALLSRTNANVFDEAVRVTEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 GVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGDAKGQVALLSRTNANVFDEAVRVTEG 710 720 730 740 750 760 700 710 720 730 740 750 pF1KB4 EFPSRIHLIGGIKSFGLDRIIDIWILLQPEEERRKQNLVIKDKFIRRWVHKEGFSGFKRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 EFPSRIHLIGGIKSFGLDRIIDIWILLQPEEERRKQNLVIKDKFIRRWVHKEGFSGFKRY 770 780 790 800 810 820 760 770 780 790 800 810 pF1KB4 VTAAEDKELEAKIAVVEKYNIRIPELVQRIEKCHIEDLDFAEYILGTVHKAKGLEFDTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 VTAAEDKELEAKIAVVEKYNIRIPELVQRIEKCHIEDLDFAEYILGTVHKAKGLEFDTVH 830 840 850 860 870 880 820 830 840 850 860 870 pF1KB4 VLDDFVKVPCARHNLPQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 VLDDFVKVPCARHNLPQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGE 890 900 910 920 930 940 880 890 900 910 920 930 pF1KB4 YFLQAELTSNVLKTGVVRCCVGQCNNAIPVDTVLTMKKLPITYSNRKENKGGYLCHSCAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 YFLQAELTSNVLKTGVVRCCVGQCNNAIPVDTVLTMKKLPITYSNRKENKGGYLCHSCAE 950 960 970 980 990 1000 940 950 960 pF1KB4 QRIGPLAFLTASPEQVRAMERTVENIVLPRHEALLFLVF ::::::::::::::::::::::::::::::::::::::: CCDS70 QRIGPLAFLTASPEQVRAMERTVENIVLPRHEALLFLVF 1010 1020 1030 1040 >>CCDS7073.1 FBXO18 gene_id:84893|Hs108|chr10 (1094 aa) initn: 6499 init1: 6499 opt: 6499 Z-score: 6423.0 bits: 1200.1 E(32554): 0 Smith-Waterman score: 6499; 100.0% identity (100.0% similar) in 969 aa overlap (1-969:126-1094) 10 20 30 pF1KB4 MAKSNSVGQDSCQDSEGDMIFPAESSCALP :::::::::::::::::::::::::::::: CCDS70 PRTKRGSRGQGSQRCIPEFFLAGKQPCTNDMAKSNSVGQDSCQDSEGDMIFPAESSCALP 100 110 120 130 140 150 40 50 60 70 80 90 pF1KB4 QEGSAGPGSPGSAPPSRKRSWSSEEESNQATGTSRWDGVSKKAPRHHLSVPCTRPREARQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 QEGSAGPGSPGSAPPSRKRSWSSEEESNQATGTSRWDGVSKKAPRHHLSVPCTRPREARQ 160 170 180 190 200 210 100 110 120 130 140 150 pF1KB4 EAEDSTSRLSAESGETDQDAGDVGPDPIPDSYYGLLGTLPCQEALSHICSLPSEVLRHVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 EAEDSTSRLSAESGETDQDAGDVGPDPIPDSYYGLLGTLPCQEALSHICSLPSEVLRHVF 220 230 240 250 260 270 160 170 180 190 200 210 pF1KB4 AFLPVEDLYWNLSLVCHLWREIISDPLFIPWKKLYHRYLMNEEQAVSKVDGILSNCGIEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 AFLPVEDLYWNLSLVCHLWREIISDPLFIPWKKLYHRYLMNEEQAVSKVDGILSNCGIEK 280 290 300 310 320 330 220 230 240 250 260 270 pF1KB4 ESDLCVLNLIRYTATTKCSPSVDPERVLWSLRDHPLLPEAEACVRQHLPDLYAAAGGVNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 ESDLCVLNLIRYTATTKCSPSVDPERVLWSLRDHPLLPEAEACVRQHLPDLYAAAGGVNI 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB4 WALVAAVVLLSSSVNDIQRLLFCLRRPSSTVTMPDVTETLYCIAVLLYAMREKGINISNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 WALVAAVVLLSSSVNDIQRLLFCLRRPSSTVTMPDVTETLYCIAVLLYAMREKGINISNR 400 410 420 430 440 450 340 350 360 370 380 390 pF1KB4 IHYNIFYCLYLQENSCTQATKVKEEPSVWPGKKTIQLTHEQQLILNHKMEPLQVVKIMAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 IHYNIFYCLYLQENSCTQATKVKEEPSVWPGKKTIQLTHEQQLILNHKMEPLQVVKIMAF 460 470 480 490 500 510 400 410 420 430 440 450 pF1KB4 AGTGKTSTLVKYAEKWSQSRFLYVTFNKSIAKQAERVFPSNVICKTFHSMAYGHIGRKYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 AGTGKTSTLVKYAEKWSQSRFLYVTFNKSIAKQAERVFPSNVICKTFHSMAYGHIGRKYQ 520 530 540 550 560 570 460 470 480 490 500 510 pF1KB4 SKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 SKKKLNLFKLTPFMVNSVLAEGKGGFIRAKLVCKTLENFFASADEELTIDHVPIWCKNSQ 580 590 600 610 620 630 520 530 540 550 560 570 pF1KB4 GQRVMVEQSEKLNGVLEASRLWDNMRKLGECTEEAHQMTHDGYLKLWQLSKPSLASFDAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 GQRVMVEQSEKLNGVLEASRLWDNMRKLGECTEEAHQMTHDGYLKLWQLSKPSLASFDAI 640 650 660 670 680 690 580 590 600 610 620 630 pF1KB4 FVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQQIYTFRGAVNALFTVPHTHVFYLTQSFRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 FVDEAQDCTPAIMNIVLSQPCGKIFVGDPHQQIYTFRGAVNALFTVPHTHVFYLTQSFRF 700 710 720 730 740 750 640 650 660 670 680 690 pF1KB4 GVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGDAKGQVALLSRTNANVFDEAVRVTEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 GVEIAYVGATILDVCKRVRKKTLVGGNHQSGIRGDAKGQVALLSRTNANVFDEAVRVTEG 760 770 780 790 800 810 700 710 720 730 740 750 pF1KB4 EFPSRIHLIGGIKSFGLDRIIDIWILLQPEEERRKQNLVIKDKFIRRWVHKEGFSGFKRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 EFPSRIHLIGGIKSFGLDRIIDIWILLQPEEERRKQNLVIKDKFIRRWVHKEGFSGFKRY 820 830 840 850 860 870 760 770 780 790 800 810 pF1KB4 VTAAEDKELEAKIAVVEKYNIRIPELVQRIEKCHIEDLDFAEYILGTVHKAKGLEFDTVH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 VTAAEDKELEAKIAVVEKYNIRIPELVQRIEKCHIEDLDFAEYILGTVHKAKGLEFDTVH 880 890 900 910 920 930 820 830 840 850 860 870 pF1KB4 VLDDFVKVPCARHNLPQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 VLDDFVKVPCARHNLPQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGE 940 950 960 970 980 990 880 890 900 910 920 930 pF1KB4 YFLQAELTSNVLKTGVVRCCVGQCNNAIPVDTVLTMKKLPITYSNRKENKGGYLCHSCAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS70 YFLQAELTSNVLKTGVVRCCVGQCNNAIPVDTVLTMKKLPITYSNRKENKGGYLCHSCAE 1000 1010 1020 1030 1040 1050 940 950 960 pF1KB4 QRIGPLAFLTASPEQVRAMERTVENIVLPRHEALLFLVF ::::::::::::::::::::::::::::::::::::::: CCDS70 QRIGPLAFLTASPEQVRAMERTVENIVLPRHEALLFLVF 1060 1070 1080 1090 >>CCDS73064.1 FBXO18 gene_id:84893|Hs108|chr10 (986 aa) initn: 5330 init1: 5330 opt: 5341 Z-score: 5278.9 bits: 988.2 E(32554): 0 Smith-Waterman score: 6455; 98.3% identity (98.3% similar) in 986 aa overlap (1-969:1-986) 10 20 30 40 50 60 pF1KB4 MAKSNSVGQDSCQDSEGDMIFPAESSCALPQEGSAGPGSPGSAPPSRKRSWSSEEESNQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MAKSNSVGQDSCQDSEGDMIFPAESSCALPQEGSAGPGSPGSAPPSRKRSWSSEEESNQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 TGTSRWDGVSKKAPRHHLSVPCTRPREARQEAEDSTSRLSAESGETDQDAGDVGPDPIPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 TGTSRWDGVSKKAPRHHLSVPCTRPREARQEAEDSTSRLSAESGETDQDAGDVGPDPIPD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SYYGLLGTLPCQEALSHICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 SYYGLLGTLPCQEALSHICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 WKKLYHRYLMNEEQAVSKVDGILSNCGIEKESDLCVLNLIRYTATTKCSPSVDPERVLWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 WKKLYHRYLMNEEQAVSKVDGILSNCGIEKESDLCVLNLIRYTATTKCSPSVDPERVLWS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LRDHPLLPEAEACVRQHLPDLYAAAGGVNIWALVAAVVLLSSSVNDIQRLLFCLRRPSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LRDHPLLPEAEACVRQHLPDLYAAAGGVNIWALVAAVVLLSSSVNDIQRLLFCLRRPSST 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VTMPDVTETLYCIAVLLYAMREKGINISNRIHYNIFYCLYLQENSCTQATKVKEEPSVWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 VTMPDVTETLYCIAVLLYAMREKGINISNRIHYNIFYCLYLQENSCTQATKVKEEPSVWP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 GKKTIQLTHEQQLILNHKMEPLQVVKIMAFAGTGKTSTLVKYAEKWSQSRFLYVTFNKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 GKKTIQLTHEQQLILNHKMEPLQVVKIMAFAGTGKTSTLVKYAEKWSQSRFLYVTFNKSI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 AKQAERVFPSNVICKTFHSMAYGHIGRKYQSKKKLNLFKLTPFMVNSVLAEGKGGFIRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 AKQAERVFPSNVICKTFHSMAYGHIGRKYQSKKKLNLFKLTPFMVNSVLAEGKGGFIRAK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 LVCKTLENFFASADEELTIDHVPIWCKNSQGQRVMVEQSEKLNGVLEASRLWDNMRKLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LVCKTLENFFASADEELTIDHVPIWCKNSQGQRVMVEQSEKLNGVLEASRLWDNMRKLGE 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 CTEEAHQMTHDGYLKLWQLSKPSLASFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 CTEEAHQMTHDGYLKLWQLSKPSLASFDAIFVDEAQDCTPAIMNIVLSQPCGKIFVGDPH 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 QQIYTFRGAVNALFTVPHTHVFYLTQSFRFGVEIAYVGATILDVCKRVRKKTLVGGNHQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 QQIYTFRGAVNALFTVPHTHVFYLTQSFRFGVEIAYVGATILDVCKRVRKKTLVGGNHQS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 GIRGDAKGQVALLSRTNANVFDEAVRVTEGEFPSRIHLIGGIKSFGLDRIIDIWILLQPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 GIRGDAKGQVALLSRTNANVFDEAVRVTEGEFPSRIHLIGGIKSFGLDRIIDIWILLQPE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 EERRKQNLVIKDKFIRRWVHKEGFSGFKRYVTAAEDKELEAKIAVVEKYNIRIPELVQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EERRKQNLVIKDKFIRRWVHKEGFSGFKRYVTAAEDKELEAKIAVVEKYNIRIPELVQRI 730 740 750 760 770 780 790 800 810 820 pF1KB4 EKCHIEDLDFAE-----------------YILGTVHKAKGLEFDTVHVLDDFVKVPCARH :::::::::::: ::::::::::::::::::::::::::::::: CCDS73 EKCHIEDLDFAEMESHHVGQAGLELPTSEYILGTVHKAKGLEFDTVHVLDDFVKVPCARH 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB4 NLPQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGEYFLQAELTSNVLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 NLPQLPHFRVESFSEDEWNLLYVAVTRAKKRLIMTKSLENILTLAGEYFLQAELTSNVLK 850 860 870 880 890 900 890 900 910 920 930 940 pF1KB4 TGVVRCCVGQCNNAIPVDTVLTMKKLPITYSNRKENKGGYLCHSCAEQRIGPLAFLTASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 TGVVRCCVGQCNNAIPVDTVLTMKKLPITYSNRKENKGGYLCHSCAEQRIGPLAFLTASP 910 920 930 940 950 960 950 960 pF1KB4 EQVRAMERTVENIVLPRHEALLFLVF :::::::::::::::::::::::::: CCDS73 EQVRAMERTVENIVLPRHEALLFLVF 970 980 969 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:21:27 2016 done: Thu Nov 3 14:21:28 2016 Total Scan time: 4.560 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]