Result of FASTA (omim) for
pF1KB4038
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4038, 363 aa
1>>>pF1KB4038 363 - 363 aa - 363 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4465+/-0.000302; mu= 9.2869+/- 0.019
mean_var=164.5285+/-33.221, 0's: 0 Z-trim(122.5): 91 B-trim: 0 in 0/54
Lambda= 0.099989
statistics sampled from 40585 (40690) to 40585 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.477), width: 16
Scan time: 9.460
The best scores are: opt bits E(85289)
NP_001017368 (OMIM: 609735) E3 ubiquitin-protein l ( 363) 2533 376.6 4.7e-104
NP_079402 (OMIM: 608299) E3 ubiquitin-protein liga ( 372) 981 152.8 1.2e-36
NP_919247 (OMIM: 608299) E3 ubiquitin-protein liga ( 373) 981 152.8 1.2e-36
NP_001243787 (OMIM: 608299) E3 ubiquitin-protein l ( 180) 607 98.5 1.2e-20
NP_001243095 (OMIM: 601712) baculoviral IAP repeat ( 569) 205 41.0 0.0082
NP_001243092 (OMIM: 601712) baculoviral IAP repeat ( 618) 205 41.0 0.0087
NP_001157 (OMIM: 601712) baculoviral IAP repeat-co ( 618) 205 41.0 0.0087
>>NP_001017368 (OMIM: 609735) E3 ubiquitin-protein ligas (363 aa)
initn: 2533 init1: 2533 opt: 2533 Z-score: 1989.1 bits: 376.6 E(85289): 4.7e-104
Smith-Waterman score: 2533; 100.0% identity (100.0% similar) in 363 aa overlap (1-363:1-363)
10 20 30 40 50 60
pF1KB4 MWATCCNWFCLDGQPEEVPPPQGARMQAYSNPGYSSFPSPTGLEPSCKSCGAHFANTARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWATCCNWFCLDGQPEEVPPPQGARMQAYSNPGYSSFPSPTGLEPSCKSCGAHFANTARK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QTCLDCKKNFCMTCSSQVGNGPRLCLLCQRFRATAFQREELMKMKVKDLRDYLSLHDIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTCLDCKKNFCMTCSSQVGNGPRLCLLCQRFRATAFQREELMKMKVKDLRDYLSLHDIST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EMCREKEELVLLVLGQQPVISQEDRTRASTLSPDFPEQQAFLTQPHSSMVPPTSPNLPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMCREKEELVLLVLGQQPVISQEDRTRASTLSPDFPEQQAFLTQPHSSMVPPTSPNLPSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SAQATSVPPAQVQENQQANGHVSQDQEEPVYLESVARVPAEDETQSIDSEDSFVPGRRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAQATSVPPAQVQENQQANGHVSQDQEEPVYLESVARVPAEDETQSIDSEDSFVPGRRAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 LSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 DQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHV
310 320 330 340 350 360
pF1KB4 FRS
:::
NP_001 FRS
>>NP_079402 (OMIM: 608299) E3 ubiquitin-protein ligase R (372 aa)
initn: 939 init1: 432 opt: 981 Z-score: 779.0 bits: 152.8 E(85289): 1.2e-36
Smith-Waterman score: 981; 44.2% identity (69.1% similar) in 382 aa overlap (1-363:8-372)
10 20 30 40
pF1KB4 MWATCCNWF-------CLDGQPEEVPPPQGARMQAYSNPGYSSFPSPTGLE-P
:::.::. . . :: : .. :: .:..: :.. : :
NP_079 MKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGP-FRFTPNPEFSTYP-PAATEGP
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 S--CKSCGAHFANTARKQTCLDCKKNFCMTCSSQVGNGPRLCLLCQRFRATAFQREELMK
. ::.:: :. .:..: ::::.:: .:: . .. : : :. .. ::::: .::.
NP_079 NIVCKACGLSFSVFRKKHVCCDCKKDFCSVCSV-LQENLRRCSTCHLLQETAFQRPQLMR
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB4 MKVKDLRDYLSLHDISTEMCREKEELVLLVLGQQPVISQEDRTRASTLSPDFPEQQAFLT
.::::::.:: :..: . :::::.:: ::: .. . :..: .:.:. . . ..:.:
NP_079 LKVKDLRQYLILRNIPIDTCREKEDLVDLVLCHHGLGSEDDMD-TSSLNSSRSQTSSFFT
120 130 140 150 160 170
170 180 190 200 210
pF1KB4 QPHSSMVPPTSPNLPSSSAQ---------ATSVPPAQVQENQQANGHVSQDQEEPVYLES
. : :.:. :: : . : ::::: .. ..... .:... ..
NP_079 RSFFSNY--TAPSATMSSFQGELMDGDQTSRSGVPAQVQ-SEITSANTEDDDDDDDEDDD
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB4 VARVPAEDETQSIDSEDSFVPGRRASLSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCE
. :::.. ....: :::::::..:.:.::..:::::::::::::::.::::
NP_079 DEEENAEDRNPGLSKERV-----RASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCE
240 250 260 270 280
280 290 300 310 320 330
pF1KB4 KWELMERVTRLYKDQKGLQHLVSGAEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHM
::::.:.:.::::... :. : . : . . ...::.::::. :::::::::::
NP_079 KWELVEKVNRLYKENEENQKSY-GERLQ----LQDEEDDSLCRICMDAVIDCVLLECGHM
290 300 310 320 330 340
340 350 360
pF1KB4 VTCTKCGKRMNECPICRQYVIRAVHVFRS
::::::::::.:::::::::.::::::.:
NP_079 VTCTKCGKRMSECPICRQYVVRAVHVFKS
350 360 370
>>NP_919247 (OMIM: 608299) E3 ubiquitin-protein ligase R (373 aa)
initn: 939 init1: 432 opt: 981 Z-score: 779.0 bits: 152.8 E(85289): 1.2e-36
Smith-Waterman score: 981; 44.2% identity (69.1% similar) in 382 aa overlap (1-363:9-373)
10 20 30 40
pF1KB4 MWATCCNWF-------CLDGQPEEVPPPQGARMQAYSNPGYSSFPSPTGLE-
:::.::. . . :: : .. :: .:..: :.. :
NP_919 MRKAGATSMWASCCGLLNEVMGTGAVRGQQSAFAGATGP-FRFTPNPEFSTYP-PAATEG
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 PS--CKSCGAHFANTARKQTCLDCKKNFCMTCSSQVGNGPRLCLLCQRFRATAFQREELM
:. ::.:: :. .:..: ::::.:: .:: . .. : : :. .. ::::: .::
NP_919 PNIVCKACGLSFSVFRKKHVCCDCKKDFCSVCSV-LQENLRRCSTCHLLQETAFQRPQLM
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB4 KMKVKDLRDYLSLHDISTEMCREKEELVLLVLGQQPVISQEDRTRASTLSPDFPEQQAFL
..::::::.:: :..: . :::::.:: ::: .. . :..: .:.:. . . ..:.
NP_919 RLKVKDLRQYLILRNIPIDTCREKEDLVDLVLCHHGLGSEDDMD-TSSLNSSRSQTSSFF
120 130 140 150 160 170
170 180 190 200 210
pF1KB4 TQPHSSMVPPTSPNLPSSSAQ---------ATSVPPAQVQENQQANGHVSQDQEEPVYLE
:. : :.:. :: : . : ::::: .. ..... .:... .
NP_919 TRSFFSNY--TAPSATMSSFQGELMDGDQTSRSGVPAQVQ-SEITSANTEDDDDDDDEDD
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB4 SVARVPAEDETQSIDSEDSFVPGRRASLSDLTDLEDIEGLTVRQLKEILARNFVNYKGCC
. . :::.. ....: :::::::..:.:.::..:::::::::::::::.:::
NP_919 DDEEENAEDRNPGLSKERV-----RASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCC
240 250 260 270 280
280 290 300 310 320 330
pF1KB4 EKWELMERVTRLYKDQKGLQHLVSGAEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGH
:::::.:.:.::::... :. : . : . . ...::.::::. ::::::::::
NP_919 EKWELVEKVNRLYKENEENQKSY-GERLQ----LQDEEDDSLCRICMDAVIDCVLLECGH
290 300 310 320 330 340
340 350 360
pF1KB4 MVTCTKCGKRMNECPICRQYVIRAVHVFRS
:::::::::::.:::::::::.::::::.:
NP_919 MVTCTKCGKRMSECPICRQYVVRAVHVFKS
350 360 370
>>NP_001243787 (OMIM: 608299) E3 ubiquitin-protein ligas (180 aa)
initn: 636 init1: 339 opt: 607 Z-score: 491.6 bits: 98.5 E(85289): 1.2e-20
Smith-Waterman score: 621; 54.9% identity (80.6% similar) in 175 aa overlap (189-363:17-180)
160 170 180 190 200 210
pF1KB4 QAFLTQPHSSMVPPTSPNLPSSSAQATSVPPAQVQENQQANGHVSQDQEEPVYLESVARV
::::: .. ..... .:... .. .
NP_001 MKGELMDGDQTSRSGVPAQVQ-SEITSANTEDDDDDDDEDDDDEEE
10 20 30 40
220 230 240 250 260 270
pF1KB4 PAEDETQSIDSEDSFVPGRRASLSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCEKWEL
:::.. ....: :::::::..:.:.::..:::::::::::::::.::::::::
NP_001 NAEDRNPGLSKERV-----RASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEKWEL
50 60 70 80 90 100
280 290 300 310 320 330
pF1KB4 MERVTRLYKDQKGLQHLVSGAEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCT
.:.:.::::... :. : . : . . ...::.::::. :::::::::::::::
NP_001 VEKVNRLYKENEENQK-SYGERLQ----LQDEEDDSLCRICMDAVIDCVLLECGHMVTCT
110 120 130 140 150
340 350 360
pF1KB4 KCGKRMNECPICRQYVIRAVHVFRS
::::::.:::::::::.::::::.:
NP_001 KCGKRMSECPICRQYVVRAVHVFKS
160 170 180
>>NP_001243095 (OMIM: 601712) baculoviral IAP repeat-con (569 aa)
initn: 185 init1: 185 opt: 205 Z-score: 171.5 bits: 41.0 E(85289): 0.0082
Smith-Waterman score: 205; 33.3% identity (62.7% similar) in 102 aa overlap (269-363:475-569)
240 250 260 270 280 290
pF1KB4 ASLSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKD---QKGLQHL
.:.: : : . :::. .:.....
NP_001 DIIKQKTQIPLQARELIDTILVKGNAAANIFKNC-----LKEIDSTLYKNLFVDKNMKYI
450 460 470 480 490
300 310 320 330 340 350
pF1KB4 VSGAEDQNGGAVPSGL----EENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICR
. :: .: .. : :: ::.:::. .. :.. :::.:.: .:. . .:::::
NP_001 PT--EDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICR
500 510 520 530 540 550
360
pF1KB4 QYVIRAVHVFRS
. .:..: :
NP_001 GIIKGTVRTFLS
560
>>NP_001243092 (OMIM: 601712) baculoviral IAP repeat-con (618 aa)
initn: 185 init1: 185 opt: 205 Z-score: 171.0 bits: 41.0 E(85289): 0.0087
Smith-Waterman score: 205; 33.3% identity (62.7% similar) in 102 aa overlap (269-363:524-618)
240 250 260 270 280 290
pF1KB4 ASLSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKD---QKGLQHL
.:.: : : . :::. .:.....
NP_001 DIIKQKTQIPLQARELIDTILVKGNAAANIFKNC-----LKEIDSTLYKNLFVDKNMKYI
500 510 520 530 540
300 310 320 330 340 350
pF1KB4 VSGAEDQNGGAVPSGL----EENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICR
. :: .: .. : :: ::.:::. .. :.. :::.:.: .:. . .:::::
NP_001 PT--EDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICR
550 560 570 580 590 600
360
pF1KB4 QYVIRAVHVFRS
. .:..: :
NP_001 GIIKGTVRTFLS
610
>>NP_001157 (OMIM: 601712) baculoviral IAP repeat-contai (618 aa)
initn: 185 init1: 185 opt: 205 Z-score: 171.0 bits: 41.0 E(85289): 0.0087
Smith-Waterman score: 205; 33.3% identity (62.7% similar) in 102 aa overlap (269-363:524-618)
240 250 260 270 280 290
pF1KB4 ASLSDLTDLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKD---QKGLQHL
.:.: : : . :::. .:.....
NP_001 DIIKQKTQIPLQARELIDTILVKGNAAANIFKNC-----LKEIDSTLYKNLFVDKNMKYI
500 510 520 530 540
300 310 320 330 340 350
pF1KB4 VSGAEDQNGGAVPSGL----EENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICR
. :: .: .. : :: ::.:::. .. :.. :::.:.: .:. . .:::::
NP_001 PT--EDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICR
550 560 570 580 590 600
360
pF1KB4 QYVIRAVHVFRS
. .:..: :
NP_001 GIIKGTVRTFLS
610
363 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:33:56 2016 done: Sat Nov 5 05:33:57 2016
Total Scan time: 9.460 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]