FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3981, 182 aa 1>>>pF1KB3981 182 - 182 aa - 182 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3298+/-0.000413; mu= 13.0541+/- 0.026 mean_var=92.0512+/-20.015, 0's: 0 Z-trim(112.9): 299 B-trim: 1121 in 2/53 Lambda= 0.133678 statistics sampled from 21630 (22038) to 21630 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.258), width: 16 Scan time: 5.780 The best scores are: opt bits E(85289) NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 1189 239.2 2.7e-63 XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 1189 239.2 2.7e-63 NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 663 137.8 9.4e-33 NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 541 114.3 1.1e-25 XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 541 114.3 1.1e-25 NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 536 113.3 2.2e-25 NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 536 113.3 2.2e-25 NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 536 113.3 2.2e-25 NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 536 113.3 2.2e-25 NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 531 112.3 4.3e-25 NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 524 111.0 1.1e-24 NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 514 109.0 4.1e-24 NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 506 107.5 1.2e-23 NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 505 107.3 1.4e-23 XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 509 108.4 1.4e-23 NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 509 108.6 1.8e-23 NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 486 103.7 1.7e-22 NP_001186674 (OMIM: 601175) ADP-ribosylation facto ( 157) 481 102.6 3.1e-22 NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 468 100.2 2.1e-21 XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 468 100.2 2.1e-21 NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 467 100.0 2.3e-21 XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 460 99.1 1.3e-20 NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 460 99.1 1.3e-20 NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 425 91.8 4.9e-19 NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 426 92.1 5.4e-19 NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 426 92.1 5.4e-19 NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 426 92.1 5.4e-19 XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 426 92.1 5.4e-19 NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 423 91.5 8.3e-19 NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 428 92.9 9e-19 NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 415 90.0 2.4e-18 NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 415 90.0 2.5e-18 XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 412 89.3 2.9e-18 NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 405 88.1 9.5e-18 XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 405 88.1 9.5e-18 NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 401 87.3 1.6e-17 NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 401 87.3 1.6e-17 NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 401 87.3 1.6e-17 NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 401 87.3 1.6e-17 NP_003215 (OMIM: 604699) ADP-ribosylation factor-r ( 201) 397 86.5 2.8e-17 NP_001254476 (OMIM: 604699) ADP-ribosylation facto ( 201) 397 86.5 2.8e-17 XP_011526785 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 397 86.5 2.8e-17 XP_011526784 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 397 86.5 2.8e-17 NP_001254477 (OMIM: 604699) ADP-ribosylation facto ( 201) 397 86.5 2.8e-17 XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 397 86.5 2.8e-17 NP_001032251 (OMIM: 608960) ADP-ribosylation facto ( 142) 391 85.2 4.8e-17 NP_817114 (OMIM: 608960) ADP-ribosylation factor-l ( 142) 391 85.2 4.8e-17 XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 388 84.6 7e-17 XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 388 84.8 9.6e-17 NP_060654 (OMIM: 616596) ADP-ribosylation factor-l ( 186) 370 81.3 9.7e-16 >>NP_004302 (OMIM: 604695) ADP-ribosylation factor-like (182 aa) initn: 1189 init1: 1189 opt: 1189 Z-score: 1257.3 bits: 239.2 E(85289): 2.7e-63 Smith-Waterman score: 1189; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK 130 140 150 160 170 180 pF1KB3 KK :: NP_004 KK >>XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosylatio (182 aa) initn: 1189 init1: 1189 opt: 1189 Z-score: 1257.3 bits: 239.2 E(85289): 2.7e-63 Smith-Waterman score: 1189; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK 130 140 150 160 170 180 pF1KB3 KK :: XP_016 KK >>NP_001658 (OMIM: 601175) ADP-ribosylation factor-like (184 aa) initn: 661 init1: 594 opt: 663 Z-score: 709.0 bits: 137.8 E(85289): 9.4e-33 Smith-Waterman score: 663; 53.3% identity (83.9% similar) in 180 aa overlap (1-180:1-179) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG ::::.::.:.:. ..:.:.:.::::::::::.::.. .:::. :.:: :::::... .: NP_001 MGLLTILKKMKQK-ERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLEHRG 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP ::::.::.:::...: ::.::::.:: ::.:.:::::.:... .:: :: ::.:. . NP_001 FKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLVEERLAGAT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK .::::::::: : .. : : :.: .::.. : ::.:::.:::.. :..:. ..... NP_001 LLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDWLLDDISSR 120 130 140 150 160 170 pF1KB3 KK NP_001 IFTAD 180 >>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa) initn: 541 init1: 541 opt: 541 Z-score: 581.9 bits: 114.3 E(85289): 1.1e-25 Smith-Waterman score: 541; 46.4% identity (78.9% similar) in 166 aa overlap (16-181:16-181) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG .:.:::..::: :::::.: .: .: :: :::...:. .. NP_001 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP ....:::.::: :::: :..::.::. ::.:.:: ::.: .:. .:: ..: :..: . NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK .:.::::::: .: :.::.. :.::..: : : ::. : .:.:. .:..:. .... : NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 pF1KB3 KK : NP_001 K >>XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosylatio (181 aa) initn: 541 init1: 541 opt: 541 Z-score: 581.9 bits: 114.3 E(85289): 1.1e-25 Smith-Waterman score: 541; 46.4% identity (78.9% similar) in 166 aa overlap (16-181:16-181) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG .:.:::..::: :::::.: .: .: :: :::...:. .. XP_005 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP ....:::.::: :::: :..::.::. ::.:.:: ::.: .:. .:: ..: :..: . XP_005 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK .:.::::::: .: :.::.. :.::..: : : ::. : .:.:. .:..:. .... : XP_005 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 pF1KB3 KK : XP_005 K >>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 554 init1: 536 opt: 536 Z-score: 576.7 bits: 113.3 E(85289): 2.2e-25 Smith-Waterman score: 536; 45.8% identity (78.3% similar) in 166 aa overlap (16-181:16-181) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG .:.:::..::: :::::.: .: .: :: :::...:. .. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP ....:::.::: :::: :..::.::. ::.:.:: ::.: .:. .:: ..: :..: . NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK .:.::::::: .: :.::.. :.::..: : : ::. : .:.:. .:..:. ... . NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB3 KK : NP_001 K >>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa) initn: 554 init1: 536 opt: 536 Z-score: 576.7 bits: 113.3 E(85289): 2.2e-25 Smith-Waterman score: 536; 45.8% identity (78.3% similar) in 166 aa overlap (16-181:16-181) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG .:.:::..::: :::::.: .: .: :: :::...:. .. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP ....:::.::: :::: :..::.::. ::.:.:: ::.: .:. .:: ..: :..: . NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK .:.::::::: .: :.::.. :.::..: : : ::. : .:.:. .:..:. ... . NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB3 KK : NP_001 K >>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 554 init1: 536 opt: 536 Z-score: 576.7 bits: 113.3 E(85289): 2.2e-25 Smith-Waterman score: 536; 45.8% identity (78.3% similar) in 166 aa overlap (16-181:16-181) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG .:.:::..::: :::::.: .: .: :: :::...:. .. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP ....:::.::: :::: :..::.::. ::.:.:: ::.: .:. .:: ..: :..: . NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK .:.::::::: .: :.::.. :.::..: : : ::. : .:.:. .:..:. ... . NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB3 KK : NP_001 K >>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 554 init1: 536 opt: 536 Z-score: 576.7 bits: 113.3 E(85289): 2.2e-25 Smith-Waterman score: 536; 45.8% identity (78.3% similar) in 166 aa overlap (16-181:16-181) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG .:.:::..::: :::::.: .: .: :: :::...:. .. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP ....:::.::: :::: :..::.::. ::.:.:: ::.: .:. .:: ..: :..: . NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK .:.::::::: .: :.::.. :.::..: : : ::. : .:.:. .:..:. ... . NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB3 KK : NP_001 K >>NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 [Ho (180 aa) initn: 549 init1: 531 opt: 531 Z-score: 571.5 bits: 112.3 E(85289): 4.3e-25 Smith-Waterman score: 531; 43.6% identity (79.4% similar) in 165 aa overlap (16-180:16-180) 10 20 30 40 50 60 pF1KB3 MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQG ...:::..::: :::::.: .: .: :: :::...:. .. NP_001 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVP . ..:::.::: :::: :..::.::. ::.:.:: ::.: .:...:: ..:.:..: . NP_001 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 VLIFANKQDLLTAAPASEIAEGLNLHTIRDRVWQIQSCSALTGEGVQDGMNWVCKNVNAK .:.::::::. .: :.::... :.:. .:.:.: .:. : : :. ::..:. .... . NP_001 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR 130 140 150 160 170 180 pF1KB3 KK 182 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:30:04 2016 done: Sat Nov 5 05:30:05 2016 Total Scan time: 5.780 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]