Result of FASTA (ccds) for
pF1KB3969
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3969, 192 aa
1>>>pF1KB3969 192 - 192 aa - 192 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5476+/-0.000903; mu= 12.2390+/- 0.055
mean_var=78.1209+/-15.810, 0's: 0 Z-trim(107.8): 168 B-trim: 279 in 1/49
Lambda= 0.145108
statistics sampled from 9597 (9786) to 9597 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.301), width: 16
Scan time: 2.040
The best scores are: opt bits E(32554)
CCDS33717.1 NKIRAS1 gene_id:28512|Hs108|chr3 ( 192) 1244 269.5 9e-73
CCDS11415.1 NKIRAS2 gene_id:28511|Hs108|chr17 ( 191) 907 198.9 1.5e-51
CCDS45679.1 NKIRAS2 gene_id:28511|Hs108|chr17 ( 135) 369 86.2 9.4e-18
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 297 71.2 4.2e-13
CCDS45680.1 NKIRAS2 gene_id:28511|Hs108|chr17 ( 97) 282 67.9 2.2e-12
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 285 68.7 2.4e-12
CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11 ( 204) 285 68.7 2.6e-12
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 284 68.5 2.8e-12
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 282 68.1 3.7e-12
CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 ( 183) 270 65.6 2.1e-11
CCDS12774.1 RRAS gene_id:6237|Hs108|chr19 ( 218) 267 65.0 3.7e-11
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 261 63.7 7.2e-11
CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 260 63.5 9.7e-11
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 260 63.5 9.7e-11
>>CCDS33717.1 NKIRAS1 gene_id:28512|Hs108|chr3 (192 aa)
initn: 1244 init1: 1244 opt: 1244 Z-score: 1420.0 bits: 269.5 E(32554): 9e-73
Smith-Waterman score: 1244; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:1-192)
10 20 30 40 50 60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
130 140 150 160 170 180
190
pF1KB3 GRKNKGNSNSEN
::::::::::::
CCDS33 GRKNKGNSNSEN
190
>>CCDS11415.1 NKIRAS2 gene_id:28511|Hs108|chr17 (191 aa)
initn: 923 init1: 885 opt: 907 Z-score: 1038.7 bits: 198.9 E(32554): 1.5e-51
Smith-Waterman score: 907; 71.4% identity (93.1% similar) in 189 aa overlap (1-189:1-188)
10 20 30 40 50 60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
:::.::::::: :::::.::::::::::..: : ::.::.:..:.::::::.::...:
CCDS11 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
:::::..:.:::.: :: .::.:::::... ::::::::::::::: ::::::.::::::
CCDS11 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
: ::.:::.:: .:::.:::::::.::::.:.::..:.:::. ::::..::::::.:::
CCDS11 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL-
130 140 150 160 170
190
pF1KB3 GRKNKGNSNSEN
.:::::...
CCDS11 SRKNKGSGSLDG
180 190
>>CCDS45679.1 NKIRAS2 gene_id:28511|Hs108|chr17 (135 aa)
initn: 625 init1: 336 opt: 369 Z-score: 432.2 bits: 86.2 E(32554): 9.4e-18
Smith-Waterman score: 521; 50.3% identity (65.6% similar) in 189 aa overlap (1-189:1-132)
10 20 30 40 50 60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
:::.::::::: :::::.::::::::::..: : ::.::.:..:.::::::.::
CCDS45 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQ----
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
:.::::::
CCDS45 ----------------------------------------------------VTIVVLGN
60
130 140 150 160 170 180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
: ::.:::.:: .:::.:::::::.::::.:.::..:.:::. ::::..::::::.:::
CCDS45 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL-
70 80 90 100 110 120
190
pF1KB3 GRKNKGNSNSEN
.:::::...
CCDS45 SRKNKGSGSLDG
130
>>CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 (188 aa)
initn: 221 init1: 161 opt: 297 Z-score: 348.7 bits: 71.2 E(32554): 4.2e-13
Smith-Waterman score: 297; 32.3% identity (62.9% similar) in 186 aa overlap (6-191:5-184)
10 20 30 40 50 60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
:.:: : .:::.:. ::. :: . : :.:: : .: : : : .
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
:: : .: . .:. ..::. :...:: .::. .. ...: . ::...: .:..::
CCDS87 DTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
: :: .: ::.. ::. :.: . . :... :. . . : :. .. . . : :
CCDS87 KCDLP-SRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMS--KD
120 130 140 150 160 170
190
pF1KB3 GRKNKGNSNSEN
:.:.: .:...
CCDS87 GKKKKKKSKTKCVIM
180
>>CCDS45680.1 NKIRAS2 gene_id:28511|Hs108|chr17 (97 aa)
initn: 282 init1: 282 opt: 282 Z-score: 335.9 bits: 67.9 E(32554): 2.2e-12
Smith-Waterman score: 282; 71.9% identity (91.2% similar) in 57 aa overlap (1-57:1-57)
10 20 30 40 50 60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
:::.::::::: :::::.::::::::::..: : ::.::.:..:.::::::.::.
CCDS45 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQIAES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
CCDS45 LFSVWSCSRRRLTNPRTRRRSPSWSLATSVTYRSSGV
70 80 90
>>CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 (189 aa)
initn: 221 init1: 161 opt: 285 Z-score: 335.1 bits: 68.7 E(32554): 2.4e-12
Smith-Waterman score: 285; 33.1% identity (62.7% similar) in 169 aa overlap (6-174:5-169)
10 20 30 40 50 60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
:.:: : .:::.:. ::. :: . : :.:: : .: : : : .
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
:: : .: . .:. ..::. :...:: .::. .. ...: . ::...: .:..::
CCDS87 DTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
: :: .: ::.. ::. :.: . . :... :. . . : :. .. : . :
CCDS87 KCDLP-SRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEE
120 130 140 150 160 170
190
pF1KB3 GRKNKGNSNSEN
CCDS87 KTPGCVKIKKCIIM
180
>>CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11 (204 aa)
initn: 232 init1: 209 opt: 285 Z-score: 334.6 bits: 68.7 E(32554): 2.6e-12
Smith-Waterman score: 285; 32.2% identity (62.3% similar) in 183 aa overlap (6-185:16-194)
10 20 30 40
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMAS-VET
..:: : .:::.:. :.. . . .. :.:: : . :
CCDS78 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDP--TIEDSYTKQCVID
10 20 30 40 50
50 60 70 80 90 100
pF1KB3 DRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKD
::... : . :: : .: . ..:. ..::.::.::.. ::... ....: . ::
CCDS78 DRAAR--LDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB3 KKEVAIVVLGNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLS
. : ....::: ::..:::: : .:: :.. :: :... : .. . : :. .
CCDS78 RDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIR
120 130 140 150 160 170
170 180 190
pF1KB3 --QPQSKSSFPLPGRKNKGNSNSEN
: : : : ::.:
CCDS78 KFQEQECPPSPEPTRKEKDKKGCHCVIF
180 190 200
>>CCDS877.1 NRAS gene_id:4893|Hs108|chr1 (189 aa)
initn: 221 init1: 162 opt: 284 Z-score: 333.9 bits: 68.5 E(32554): 2.8e-12
Smith-Waterman score: 284; 33.7% identity (61.5% similar) in 169 aa overlap (6-174:5-169)
10 20 30 40 50 60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
:.:: : .:::.:. ::. :: . : :.:: : .: : : : .
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
:: : .: . .:. ..::. :...:: .:: ..: ...: . ::. .: .:..::
CCDS87 DTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
: :: : ::.. :.. ::: . . :... :. . . : :. .. : . :
CCDS87 KCDLPT-RTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSD
120 130 140 150 160 170
190
pF1KB3 GRKNKGNSNSEN
CCDS87 DGTQGCMGLPCVVM
180
>>CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 (189 aa)
initn: 195 init1: 161 opt: 282 Z-score: 331.7 bits: 68.1 E(32554): 3.7e-12
Smith-Waterman score: 282; 31.5% identity (61.3% similar) in 181 aa overlap (6-186:5-180)
10 20 30 40 50 60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
:.:: : .:::.:. ::. :: . : :.:: : .: : : : .
CCDS76 MTEYKLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
:: : .: . .:. ..::. :...:: .::. .. ...: . ::. .: .:..::
CCDS76 DTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
: ::. : :... ::. :.: . :... :. . . : :. .. : . .. : :
CCDS76 KCDLAA-RTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNP-P
120 130 140 150 160 170
190
pF1KB3 GRKNKGNSNSEN
... :
CCDS76 DESGPGCMSCKCVLS
180
>>CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 (183 aa)
initn: 264 init1: 210 opt: 270 Z-score: 318.3 bits: 65.6 E(32554): 2.1e-11
Smith-Waterman score: 270; 32.7% identity (64.8% similar) in 165 aa overlap (6-170:8-169)
10 20 30 40 50
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLH
:::. : ::::.. .:.. :. . :.. :.:..: : . . .::
CCDS87 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDP--TVENTYSKIVTLGKD-EFHLH
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 LYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVL
: :: : .: :: .. . :.::::::..:.::: .: : ... . . : .: .:..
CCDS87 LVDTAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 GNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFP
::: ::: .:.:.: ... :.: . . : .. . . :: . .....
CCDS87 GNKADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQE
120 130 140 150 160 170
180 190
pF1KB3 LPGRKNKGNSNSEN
CCDS87 RRCHLM
180
192 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:29:29 2016 done: Sat Nov 5 05:29:30 2016
Total Scan time: 2.040 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]