Result of FASTA (omim) for
pF1KB3938
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3938, 442 aa
1>>>pF1KB3938 442 - 442 aa - 442 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4368+/-0.000371; mu= 13.8810+/- 0.024
mean_var=144.9312+/-32.343, 0's: 0 Z-trim(117.7): 558 B-trim: 3077 in 2/51
Lambda= 0.106535
statistics sampled from 29152 (29853) to 29152 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.35), width: 16
Scan time: 9.780
The best scores are: opt bits E(85289)
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 3008 474.1 3.2e-133
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 3008 474.1 3.2e-133
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 3008 474.2 3.7e-133
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 2687 424.7 2.3e-118
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 1611 259.4 1.4e-68
NP_001243212 (OMIM: 131243,157300,616367) endothel ( 202) 865 144.4 2.7e-34
NP_001159527 (OMIM: 131243,157300,616367) endothel ( 318) 817 137.2 6.1e-32
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 652 111.9 3e-24
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 627 108.1 4.3e-23
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 590 102.4 2.3e-21
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 402 73.5 1.2e-12
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 401 73.3 1.2e-12
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 401 73.3 1.2e-12
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 401 73.3 1.2e-12
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 391 71.8 3.5e-12
XP_011534148 (OMIM: 162341) PREDICTED: neuromedin- ( 283) 381 70.1 8.3e-12
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 382 70.4 9.7e-12
NP_005293 (OMIM: 602583) prosaposin receptor GPR37 ( 613) 383 70.8 1.1e-11
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 376 69.5 1.7e-11
NP_940799 (OMIM: 601898) growth hormone secretagog ( 366) 373 69.0 2.3e-11
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 372 68.9 2.7e-11
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 372 68.9 2.7e-11
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 372 68.9 2.7e-11
XP_016866390 (OMIM: 162341) PREDICTED: neuromedin- ( 301) 367 68.0 3.9e-11
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 366 67.9 5e-11
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 366 67.9 5e-11
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 366 67.9 5e-11
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 366 67.9 5e-11
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 366 67.9 5e-11
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 366 67.9 5e-11
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 365 67.8 6e-11
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 365 67.8 6e-11
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 365 67.9 7e-11
NP_001311237 (OMIM: 162341) neuromedin-B receptor ( 242) 353 65.7 1.5e-10
XP_016866391 (OMIM: 162341) PREDICTED: neuromedin- ( 242) 353 65.7 1.5e-10
NP_001311236 (OMIM: 162341) neuromedin-B receptor ( 242) 353 65.7 1.5e-10
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 355 66.3 1.6e-10
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 355 66.3 1.7e-10
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 350 65.5 3e-10
NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 342 64.2 5.9e-10
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 340 64.0 8.7e-10
XP_011535972 (OMIM: 605108) PREDICTED: neuromedin- ( 321) 335 63.1 1.2e-09
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 330 62.4 2.4e-09
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 329 62.2 2.5e-09
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 315 60.1 1.2e-08
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 312 59.6 1.5e-08
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 312 59.7 1.6e-08
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 312 59.7 1.6e-08
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 307 58.9 2.8e-08
XP_016881180 (OMIM: 600377) PREDICTED: galanin rec ( 269) 304 58.3 2.9e-08
>>NP_000106 (OMIM: 131244,277580,600155,600501) endothel (442 aa)
initn: 3008 init1: 3008 opt: 3008 Z-score: 2512.7 bits: 474.1 E(85289): 3.2e-133
Smith-Waterman score: 3008; 99.8% identity (100.0% similar) in 442 aa overlap (1-442:1-442)
10 20 30 40 50 60
pF1KB3 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEMMTPPTKTLWPKGSNA
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_000 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
370 380 390 400 410 420
430 440
pF1KB3 LKFKANDHGYDNFRSSNKYSSS
::::::::::::::::::::::
NP_000 LKFKANDHGYDNFRSSNKYSSS
430 440
>>NP_001116131 (OMIM: 131244,277580,600155,600501) endot (442 aa)
initn: 3008 init1: 3008 opt: 3008 Z-score: 2512.7 bits: 474.1 E(85289): 3.2e-133
Smith-Waterman score: 3008; 99.8% identity (100.0% similar) in 442 aa overlap (1-442:1-442)
10 20 30 40 50 60
pF1KB3 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEMMTPPTKTLWPKGSNA
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
370 380 390 400 410 420
430 440
pF1KB3 LKFKANDHGYDNFRSSNKYSSS
::::::::::::::::::::::
NP_001 LKFKANDHGYDNFRSSNKYSSS
430 440
>>NP_001188326 (OMIM: 131244,277580,600155,600501) endot (532 aa)
initn: 3008 init1: 3008 opt: 3008 Z-score: 2511.7 bits: 474.2 E(85289): 3.7e-133
Smith-Waterman score: 3008; 99.8% identity (100.0% similar) in 442 aa overlap (1-442:91-532)
10 20 30
pF1KB3 MQPPPSLCGRALVALVLACGLSRIWGEERG
::::::::::::::::::::::::::::::
NP_001 PFVALHLVCQIREALKLRSGHRTPSGAGSSMQPPPSLCGRALVALVLACGLSRIWGEERG
70 80 90 100 110 120
40 50 60 70 80 90
pF1KB3 FPPDRATPLLQTAEMMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPC
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPPDRATPLLQTAEIMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPC
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB3 QGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLH
190 200 210 220 230 240
160 170 180 190 200 210
pF1KB3 IVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIK
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB3 GIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYK
310 320 330 340 350 360
280 290 300 310 320 330
pF1KB3 TAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVL
370 380 390 400 410 420
340 350 360 370 380 390
pF1KB3 VFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVS
430 440 450 460 470 480
400 410 420 430 440
pF1KB3 KRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
490 500 510 520 530
>>NP_003982 (OMIM: 131244,277580,600155,600501) endothel (436 aa)
initn: 2711 init1: 2687 opt: 2687 Z-score: 2246.1 bits: 424.7 E(85289): 2.3e-118
Smith-Waterman score: 2687; 99.5% identity (100.0% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KB3 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEMMTPPTKTLWPKGSNA
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_003 MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
::::::::::::::::::::::::::::::::::::::.
NP_003 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSVNIECDGT
370 380 390 400 410 420
430 440
pF1KB3 LKFKANDHGYDNFRSSNKYSSS
NP_003 VNQNPTMWPERKSNNN
430
>>NP_001948 (OMIM: 131243,157300,616367) endothelin-1 re (427 aa)
initn: 988 init1: 579 opt: 1611 Z-score: 1352.5 bits: 259.4 E(85289): 1.4e-68
Smith-Waterman score: 1611; 63.8% identity (85.0% similar) in 359 aa overlap (90-440:69-425)
60 70 80 90 100 110
pF1KB3 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
: .: .:::::::.:: .:..:..::
NP_001 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB3 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF-----GAEMC
.:::::::.::::::::: ::::::::::...:::.::::.:::: ::: :. .:
NP_001 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLC
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB3 KLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAV
:: ::.::.:::::::.:::::.:::::::::::..:::.: ::.::: ::..: .::.
NP_001 KLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAI
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB3 PEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYT
:::::: .. ..:.: . :.:. ..: ::.::. .::::::.::::.::. ::.:::
NP_001 PEAIGFVMVPFEYRGEQHKTCMLNATSK--FMEFYQDVKDWWLFGFYFCMPLVCTAIFYT
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB3 LMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQN
::::::: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::.
NP_001 LMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEM
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB3 DPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQ
: ::::::::::..::::::.:..::::::::::.:::.:::::.::::: : ::
NP_001 DKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMT
340 350 360 370 380 390
420 430 440
pF1KB3 SLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
:. . . ...: .:.. : :::.: :
NP_001 SVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
400 410 420
>>NP_001243212 (OMIM: 131243,157300,616367) endothelin-1 (202 aa)
initn: 579 init1: 579 opt: 865 Z-score: 736.8 bits: 144.4 E(85289): 2.7e-34
Smith-Waterman score: 865; 60.9% identity (84.2% similar) in 202 aa overlap (242-440:1-200)
220 230 240 250 260 270
pF1KB3 IGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKT
.. ..:.: . :.:. ..: ::.::.
NP_001 MVPFEYRGEQHKTCMLNATSK--FMEFYQD
10 20
280 290 300 310 320 330
pF1KB3 AKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSG-MQIALNDHLKQRREVAKTVFCLVL
.::::::.::::.::. ::.:::::::::: ...: ..:::..::::::::::::::::.
NP_001 VKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVV
30 40 50 60 70 80
340 350 360 370 380 390
pF1KB3 VFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVS
.:::::.::::::::: :.::. : ::::::::::..::::::.:..::::::::::.::
NP_001 IFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVS
90 100 110 120 130 140
400 410 420 430 440
pF1KB3 KRFKNCFKSCLCCWC-QSFEEKQSLEEKQSCLKFKANDHGYDNF-RSSNKYSSS
:.:::::.::::: : :: :. . . ...: .:.. : :::.: :
NP_001 KKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
150 160 170 180 190 200
>>NP_001159527 (OMIM: 131243,157300,616367) endothelin-1 (318 aa)
initn: 916 init1: 579 opt: 817 Z-score: 694.5 bits: 137.2 E(85289): 6.1e-32
Smith-Waterman score: 948; 46.6% identity (61.0% similar) in 354 aa overlap (90-440:69-316)
60 70 80 90 100 110
pF1KB3 ASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGN
: .: .:::::::.:: .:..:..::
NP_001 TFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGN
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB3 STLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPF
.:::::::.::::::::: ::::::::::...:::.::::.:
NP_001 ATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFK------------------
100 110 120 130 140
180 190 200 210 220 230
pF1KB3 IQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIG
NP_001 ------------------------------------------------------------
240 250 260 270 280 290
pF1KB3 FDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCE
::. .::::::.::::.::. ::.::::::::
NP_001 ----------------------------FYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCE
150 160 170
300 310 320 330 340 350
pF1KB3 MLRKKSG-MQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRC
:: ...: ..:::..::::::::::::::::..:::::.::::::::: :.::. : :::
NP_001 MLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRC
180 190 200 210 220 230
360 370 380 390 400 410
pF1KB3 ELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWC-QSFEEKQSLEEK
:::::::..::::::.:..::::::::::.:::.:::::.::::: : :: :. .
NP_001 ELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMN
240 250 260 270 280 290
420 430 440
pF1KB3 QSCLKFKANDHGYDNF-RSSNKYSSS
. ...: .:.. : :::.: :
NP_001 GTSIQWKNHDQNNHNTDRSSHKDSMN
300 310
>>NP_002502 (OMIM: 162341) neuromedin-B receptor isoform (390 aa)
initn: 666 init1: 376 opt: 652 Z-score: 556.3 bits: 111.9 E(85289): 3e-24
Smith-Waterman score: 652; 31.7% identity (62.4% similar) in 356 aa overlap (63-411:3-349)
40 50 60 70 80 90
pF1KB3 PDRATPLLQTAEMMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPP--PC
..::. : : .:: :. :
NP_002 MPSKSLSNLSVTTGANESGSVPEGWERDFLPA
10 20 30
100 110 120 130 140 150
pF1KB3 QGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLH
. . ... . . :....:..:: :..:. :. ::. :::.:..:: ::::
NP_002 SDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB3 IVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIK
.. .:... . . ..: :: :::.: :: .:::..:..: ::: :::::... ..
NP_002 LLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQ
100 110 120 130 140 150
220 230 240 250 260
pF1KB3 GIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMD-YKGSYLRICLLHPVQKTAFMQFY
:. : :. . ::::::.::::::. .. .. .: . :. .: ...
NP_002 TSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTD----ELH
160 170 180 190 200
270 280 290 300 310 320
pF1KB3 KTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQ----RREVAKTV
.. .: :: .:::: ...: .. .... .. :.: :. :...:: :
NP_002 PKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIV
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB3 FCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIA
. .: : .::.: :. . . ::. ::. :. ..: .. .. :::.::.:
NP_002 LVFVGCFIFCWFPNHILYMYRSFNYNEIDPS----LGHMIVT-LVARVLSFGNSCVNPFA
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB3 LYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
:::.:. :. :.: ::: .:..:.
NP_002 LYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHS
330 340 350 360 370 380
>>NP_005305 (OMIM: 305670) gastrin-releasing peptide rec (384 aa)
initn: 555 init1: 384 opt: 627 Z-score: 535.7 bits: 108.1 E(85289): 4.3e-23
Smith-Waterman score: 627; 32.1% identity (65.9% similar) in 340 aa overlap (102-433:41-371)
80 90 100 110 120 130
pF1KB3 PKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKC
:. .: .....:.::: ::..:. :
NP_005 LEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKS
20 30 40 50 60 70
140 150 160 170 180 190
pF1KB3 MRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLS
::: ::..:.:::::::: .. :... . ::. : :: :::.:::: .:::..:..
NP_005 MRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFT
80 90 100 110 120 130
200 210 220 230 240 250
pF1KB3 LCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSY
: ::: :::.:.. :.. . .. ..::..:..::.:::. :. . ...
NP_005 LTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTN
140 150 160 170 180 190
260 270 280 290 300
pF1KB3 LRI--CLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQI
. : .: .. .... :. : .. .::.: . .: ... ..... .. .
NP_005 QTFISCAPYPHSNELHPKIHSMAS----FLVFYVIPLSIISVYYYFIAKNLIQSAYNLPV
200 210 220 230 240
310 320 330 340 350 360
pF1KB3 ALNDHLKQ----RREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLL
: :.:. :...::::. .: .::.:::: :. . . :.. : . .: :
NP_005 EGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTS---MLHF--
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB3 VLDYIGINMASLNSCINPIALYLVSKRFKNCFKS-CLCCWCQSFEEKQSLEEKQSCL-KF
: . . .: :::.::.::::.:: :.. :.. ::: . ...: .. .:. ..
NP_005 VTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTSL
310 320 330 340 350 360
430 440
pF1KB3 KANDHGYDNFRSSNKYSSS
:... . .:
NP_005 KSTNPSVATFSLINGNICHERYV
370 380
>>NP_001718 (OMIM: 300107) bombesin receptor subtype-3 [ (399 aa)
initn: 545 init1: 348 opt: 590 Z-score: 504.7 bits: 102.4 E(85289): 2.3e-21
Smith-Waterman score: 590; 32.9% identity (67.4% similar) in 310 aa overlap (106-407:52-350)
80 90 100 110 120 130
pF1KB3 RTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNG
.. ... .::.::. :.....:.: :..
NP_001 SSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTV
30 40 50 60 70 80
140 150 160 170 180 190
pF1KB3 PNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCAL
:::.:.:::.:::: .. .:... . ::: : :: ::.. ::. .:::..:..: :
NP_001 PNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTIL
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB3 SIDRYRAVAS-WSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITM--DYKGSYL
: :::.::.. : . .. : : :. .:.::...:.:::: .. :. :. .
NP_001 SADRYKAVVKPLERQPSNAILK-TCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTF
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB3 RICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALN
. : .::.: ...... : .. .::.: . .:.:.. . .. .. .
NP_001 ESCTSYPVSKKLLQEIHSLL----CFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQ
210 220 230 240 250
320 330 340 350 360
pF1KB3 DHLKQ----RREVAKTVFCLVLVFALCWLPLHLSRILK-LTLYNQNDPNRCELLSFLLVL
.: .. :...:.::. :: .::::::: :: . . .: . ::. ... . ..
NP_001 SHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFI--FTIF
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB3 DYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKAND
. . .: :::.::.::: .:: :.. ::. : : :..
NP_001 SRV---LAFSNSCVNPFALYWLSKSFQKHFKAQLFC-CKAERPEPPVADTSLTTLAVMGT
320 330 340 350 360 370
430 440
pF1KB3 HGYDNFRSSNKYSSS
NP_001 VPGTGSIQMSEISVTSFTGCSVKQAEDRF
380 390
442 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:44:43 2016 done: Fri Nov 4 02:44:44 2016
Total Scan time: 9.780 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]