Result of FASTA (omim) for
pF1KB3845
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3845, 350 aa
1>>>pF1KB3845 350 - 350 aa - 350 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4168+/-0.000372; mu= 16.5784+/- 0.023
mean_var=78.0064+/-15.435, 0's: 0 Z-trim(114.4): 168 B-trim: 614 in 1/53
Lambda= 0.145214
statistics sampled from 24041 (24228) to 24041 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.284), width: 16
Scan time: 8.010
The best scores are: opt bits E(85289)
NP_061979 (OMIM: 608314) neuronal-specific septin- ( 350) 2321 495.7 6.4e-140
NP_663786 (OMIM: 608314) neuronal-specific septin- ( 358) 2236 477.9 1.5e-134
XP_016884351 (OMIM: 608314) PREDICTED: neuronal-sp ( 856) 2224 475.6 1.7e-133
NP_001280625 (OMIM: 162100,604061) septin-9 isofor ( 362) 1506 324.9 1.6e-88
XP_011522509 (OMIM: 162100,604061) PREDICTED: sept ( 422) 1504 324.6 2.5e-88
NP_001106964 (OMIM: 162100,604061) septin-9 isofor ( 422) 1504 324.6 2.5e-88
XP_006721706 (OMIM: 162100,604061) PREDICTED: sept ( 422) 1504 324.6 2.5e-88
NP_001106966 (OMIM: 162100,604061) septin-9 isofor ( 422) 1504 324.6 2.5e-88
NP_001106967 (OMIM: 162100,604061) septin-9 isofor ( 474) 1504 324.6 2.7e-88
NP_001280624 (OMIM: 162100,604061) septin-9 isofor ( 567) 1504 324.7 3.1e-88
NP_006631 (OMIM: 162100,604061) septin-9 isoform c ( 568) 1504 324.7 3.1e-88
XP_011522508 (OMIM: 162100,604061) PREDICTED: sept ( 571) 1504 324.7 3.1e-88
NP_001106965 (OMIM: 162100,604061) septin-9 isofor ( 579) 1504 324.7 3.2e-88
NP_001106963 (OMIM: 162100,604061) septin-9 isofor ( 586) 1504 324.7 3.2e-88
XP_011522506 (OMIM: 162100,604061) PREDICTED: sept ( 617) 1504 324.7 3.3e-88
XP_006721707 (OMIM: 162100,604061) PREDICTED: sept ( 335) 1499 323.5 4.3e-88
XP_005257019 (OMIM: 162100,604061) PREDICTED: sept ( 335) 1499 323.5 4.3e-88
XP_016879520 (OMIM: 162100,604061) PREDICTED: sept ( 335) 1499 323.5 4.3e-88
NP_001280627 (OMIM: 162100,604061) septin-9 isofor ( 335) 1499 323.5 4.3e-88
XP_016879521 (OMIM: 162100,604061) PREDICTED: sept ( 335) 1499 323.5 4.3e-88
NP_001280626 (OMIM: 162100,604061) septin-9 isofor ( 335) 1499 323.5 4.3e-88
NP_001106968 (OMIM: 162100,604061) septin-9 isofor ( 335) 1499 323.5 4.3e-88
XP_011522510 (OMIM: 162100,604061) PREDICTED: sept ( 335) 1499 323.5 4.3e-88
XP_006720909 (OMIM: 611562,614822) PREDICTED: sept ( 358) 1316 285.1 1.6e-76
NP_653206 (OMIM: 611562,614822) septin-12 isoform ( 358) 1316 285.1 1.6e-76
XP_016878427 (OMIM: 611562,614822) PREDICTED: sept ( 364) 1176 255.8 1.1e-67
XP_011520681 (OMIM: 611562,614822) PREDICTED: sept ( 294) 1119 243.8 3.6e-64
NP_536341 (OMIM: 603696) septin-4 isoform 3 [Homo ( 459) 1060 231.6 2.7e-60
NP_001185642 (OMIM: 603696) septin-4 isoform 4 [Ho ( 470) 1060 231.6 2.7e-60
NP_004565 (OMIM: 603696) septin-4 isoform 1 [Homo ( 478) 1060 231.6 2.7e-60
XP_006722012 (OMIM: 603696) PREDICTED: septin-4 is ( 483) 1060 231.6 2.8e-60
NP_001243711 (OMIM: 603696) septin-4 isoform 5 [Ho ( 493) 1060 231.6 2.8e-60
XP_006722013 (OMIM: 603696) PREDICTED: septin-4 is ( 384) 1041 227.5 3.6e-59
XP_006722015 (OMIM: 603696) PREDICTED: septin-4 is ( 360) 1036 226.5 7.1e-59
XP_006722014 (OMIM: 603696) PREDICTED: septin-4 is ( 379) 1036 226.5 7.4e-59
NP_001011553 (OMIM: 603151) septin-7 isoform 2 [Ho ( 436) 1033 225.9 1.3e-58
XP_016868346 (OMIM: 603151) PREDICTED: septin-7 is ( 434) 1030 225.3 2e-58
XP_016868345 (OMIM: 603151) PREDICTED: septin-7 is ( 435) 1030 225.3 2e-58
XP_016868344 (OMIM: 603151) PREDICTED: septin-7 is ( 445) 1030 225.3 2e-58
NP_001779 (OMIM: 603151) septin-7 isoform 1 [Homo ( 437) 1027 224.7 3.1e-58
XP_011513963 (OMIM: 603151) PREDICTED: septin-7 is ( 440) 1027 224.7 3.1e-58
XP_006715869 (OMIM: 603151) PREDICTED: septin-7 is ( 448) 1027 224.7 3.1e-58
XP_011513958 (OMIM: 603151) PREDICTED: septin-7 is ( 460) 1027 224.7 3.2e-58
NP_002679 (OMIM: 602724) septin-5 isoform 1 [Homo ( 369) 1018 222.7 9.9e-58
NP_001307958 (OMIM: 601506) septin-2 isoform d [Ho ( 391) 981 215.0 2.2e-55
NP_001307959 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 979 214.5 2.8e-55
NP_001008491 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 979 214.5 2.8e-55
XP_016859695 (OMIM: 601506) PREDICTED: septin-2 is ( 361) 979 214.5 2.8e-55
NP_001008492 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 979 214.5 2.8e-55
NP_001307964 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 979 214.5 2.8e-55
>>NP_061979 (OMIM: 608314) neuronal-specific septin-3 is (350 aa)
initn: 2321 init1: 2321 opt: 2321 Z-score: 2633.0 bits: 495.7 E(85289): 6.4e-140
Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)
10 20 30 40 50 60
pF1KB3 MSKGLPETRTDAAMSELVPEPRPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MSKGLPETRTDAAMSELVPEPRPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 FDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALL
250 260 270 280 290 300
310 320 330 340 350
pF1KB3 RDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPVSVDTEESHDSNP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPVSVDTEESHDSNP
310 320 330 340 350
>>NP_663786 (OMIM: 608314) neuronal-specific septin-3 is (358 aa)
initn: 2236 init1: 2236 opt: 2236 Z-score: 2536.6 bits: 477.9 E(85289): 1.5e-134
Smith-Waterman score: 2236; 100.0% identity (100.0% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KB3 MSKGLPETRTDAAMSELVPEPRPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 MSKGLPETRTDAAMSELVPEPRPKPAVPMKPMSINSNLLGYIGIDTIIEQMRKKTMKTGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 DFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 LTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 TGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 FDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_663 FDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALL
250 260 270 280 290 300
310 320 330 340 350
pF1KB3 RDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPVSVDTEESHDSNP
:::::::::::::::::::::::::::::::::::::
NP_663 RDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPGEGLLGTVLPPVPATPCPTAE
310 320 330 340 350
>>XP_016884351 (OMIM: 608314) PREDICTED: neuronal-specif (856 aa)
initn: 2224 init1: 2224 opt: 2224 Z-score: 2517.7 bits: 475.6 E(85289): 1.7e-133
Smith-Waterman score: 2224; 100.0% identity (100.0% similar) in 335 aa overlap (3-337:501-835)
10 20 30
pF1KB3 MSKGLPETRTDAAMSELVPEPRPKPAVPMKPM
::::::::::::::::::::::::::::::
XP_016 SRSTDLALDNTNAAMDRATEPASLDLATEYKGLPETRTDAAMSELVPEPRPKPAVPMKPM
480 490 500 510 520 530
40 50 60 70 80 90
pF1KB3 SINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SINSNLLGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASS
540 550 560 570 580 590
100 110 120 130 140 150
pF1KB3 WNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEK
600 610 620 630 640 650
160 170 180 190 200 210
pF1KB3 FLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTM
660 670 680 690 700 710
220 230 240 250 260 270
pF1KB3 TLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQV
720 730 740 750 760 770
280 290 300 310 320 330
pF1KB3 NGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDN
780 790 800 810 820 830
340 350
pF1KB3 GGLPPVSVDTEESHDSNP
:::::
XP_016 GGLPPGEGLLGTVLPPVPATPCPTAE
840 850
>>NP_001280625 (OMIM: 162100,604061) septin-9 isoform h (362 aa)
initn: 1509 init1: 1119 opt: 1506 Z-score: 1710.0 bits: 324.9 E(85289): 1.6e-88
Smith-Waterman score: 1506; 65.6% identity (83.7% similar) in 349 aa overlap (8-350:16-360)
10 20 30 40
pF1KB3 MSKGLPETRTDAAMS---ELVPEPRPKPAVPMKPMSINSNL---LGYIGIDT
: :.:: : ... :: .. . : : : . .::.:::.
NP_001 MAGAGCTGTWSWLWGTATEAAPSCVGDMADTPRDA-GLKQAPASRNEKAPVDFGYVGIDS
10 20 30 40 50
50 60 70 80 90 100
pF1KB3 IIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIK
:.::::.:.:: ::.::::::::::::::::.::::::..:::. . . ::.::::.:::
NP_001 ILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB3 AIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARKKRI
.: : ::: ::.:::::::::::::.:::::::.:: :.::.::::.:.::::: :::::
NP_001 SITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRI
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB3 PDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRK
:::::::::::: :::::::::.::::.:::::::.::::::::.::::. .::::.
NP_001 PDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVHFKQRITA
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB3 ELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGI
.: :::. ::::::::: ::. :.:.: : .::::::::.::::::::.::::: ::
NP_001 DLLSNGIDVYPQKEFDEDSEDRLVNEKFR-EMIPFAVVGSDHEYQVNGKRILGRKTKWGT
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB3 IEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNGGLPPVSVDTEESH
::::: .::::: :::..::::.:..:..: .::.:.::.::::. : .. ::..
NP_001 IEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNE--GSSAMANGMEEKE
300 310 320 330 340 350
350
pF1KB3 DSNP
:
NP_001 PEAPEM
360
>>XP_011522509 (OMIM: 162100,604061) PREDICTED: septin-9 (422 aa)
initn: 1531 init1: 1119 opt: 1504 Z-score: 1706.8 bits: 324.6 E(85289): 2.5e-88
Smith-Waterman score: 1504; 64.0% identity (83.5% similar) in 358 aa overlap (1-350:67-420)
10 20
pF1KB3 MSKGLPETR--TDAAMS---ELVPEPRPKP
.... :... :.:: : ... ::
XP_011 APSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDA-
40 50 60 70 80 90
30 40 50 60 70 80
pF1KB3 AVPMKPMSINSNL---LGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLF
.. . : : : . .::.:::.:.::::.:.:: ::.::::::::::::::::.::::
XP_011 GLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLF
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB3 KSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPI
::..:::. . . ::.::::.:::.: : ::: ::.:::::::::::::.:::::::.::
XP_011 KSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPI
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB3 EKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNI
:.::.::::.:.::::: ::::::::::::::::: :::::::::.::::.:::::::
XP_011 MKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNI
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB3 IPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFA
.::::::::.::::. .::::. .: :::. ::::::::: ::. :.:.: : .:::
XP_011 VPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFR-EMIPFA
280 290 300 310 320 330
270 280 290 300 310 320
pF1KB3 VVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYE
:::::.::::::::.::::: :: ::::: .::::: :::..::::.:..:..: .::.:
XP_011 VVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFE
340 350 360 370 380 390
330 340 350
pF1KB3 TYRAKRLNDNGGLPPVSVDTEESHDSNP
.::.::::. : .. ::.. :
XP_011 AYRVKRLNE--GSSAMANGMEEKEPEAPEM
400 410 420
>>NP_001106964 (OMIM: 162100,604061) septin-9 isoform e (422 aa)
initn: 1531 init1: 1119 opt: 1504 Z-score: 1706.8 bits: 324.6 E(85289): 2.5e-88
Smith-Waterman score: 1504; 64.0% identity (83.5% similar) in 358 aa overlap (1-350:67-420)
10 20
pF1KB3 MSKGLPETR--TDAAMS---ELVPEPRPKP
.... :... :.:: : ... ::
NP_001 APSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDA-
40 50 60 70 80 90
30 40 50 60 70 80
pF1KB3 AVPMKPMSINSNL---LGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLF
.. . : : : . .::.:::.:.::::.:.:: ::.::::::::::::::::.::::
NP_001 GLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLF
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB3 KSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPI
::..:::. . . ::.::::.:::.: : ::: ::.:::::::::::::.:::::::.::
NP_001 KSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPI
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB3 EKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNI
:.::.::::.:.::::: ::::::::::::::::: :::::::::.::::.:::::::
NP_001 MKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNI
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB3 IPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFA
.::::::::.::::. .::::. .: :::. ::::::::: ::. :.:.: : .:::
NP_001 VPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFR-EMIPFA
280 290 300 310 320 330
270 280 290 300 310 320
pF1KB3 VVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYE
:::::.::::::::.::::: :: ::::: .::::: :::..::::.:..:..: .::.:
NP_001 VVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFE
340 350 360 370 380 390
330 340 350
pF1KB3 TYRAKRLNDNGGLPPVSVDTEESHDSNP
.::.::::. : .. ::.. :
NP_001 AYRVKRLNE--GSSAMANGMEEKEPEAPEM
400 410 420
>>XP_006721706 (OMIM: 162100,604061) PREDICTED: septin-9 (422 aa)
initn: 1531 init1: 1119 opt: 1504 Z-score: 1706.8 bits: 324.6 E(85289): 2.5e-88
Smith-Waterman score: 1504; 64.0% identity (83.5% similar) in 358 aa overlap (1-350:67-420)
10 20
pF1KB3 MSKGLPETR--TDAAMS---ELVPEPRPKP
.... :... :.:: : ... ::
XP_006 APSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDA-
40 50 60 70 80 90
30 40 50 60 70 80
pF1KB3 AVPMKPMSINSNL---LGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLF
.. . : : : . .::.:::.:.::::.:.:: ::.::::::::::::::::.::::
XP_006 GLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLF
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB3 KSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPI
::..:::. . . ::.::::.:::.: : ::: ::.:::::::::::::.:::::::.::
XP_006 KSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPI
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB3 EKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNI
:.::.::::.:.::::: ::::::::::::::::: :::::::::.::::.:::::::
XP_006 MKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNI
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB3 IPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFA
.::::::::.::::. .::::. .: :::. ::::::::: ::. :.:.: : .:::
XP_006 VPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFR-EMIPFA
280 290 300 310 320 330
270 280 290 300 310 320
pF1KB3 VVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYE
:::::.::::::::.::::: :: ::::: .::::: :::..::::.:..:..: .::.:
XP_006 VVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFE
340 350 360 370 380 390
330 340 350
pF1KB3 TYRAKRLNDNGGLPPVSVDTEESHDSNP
.::.::::. : .. ::.. :
XP_006 AYRVKRLNE--GSSAMANGMEEKEPEAPEM
400 410 420
>>NP_001106966 (OMIM: 162100,604061) septin-9 isoform e (422 aa)
initn: 1531 init1: 1119 opt: 1504 Z-score: 1706.8 bits: 324.6 E(85289): 2.5e-88
Smith-Waterman score: 1504; 64.0% identity (83.5% similar) in 358 aa overlap (1-350:67-420)
10 20
pF1KB3 MSKGLPETR--TDAAMS---ELVPEPRPKP
.... :... :.:: : ... ::
NP_001 APSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDA-
40 50 60 70 80 90
30 40 50 60 70 80
pF1KB3 AVPMKPMSINSNL---LGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLF
.. . : : : . .::.:::.:.::::.:.:: ::.::::::::::::::::.::::
NP_001 GLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLF
100 110 120 130 140 150
90 100 110 120 130 140
pF1KB3 KSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPI
::..:::. . . ::.::::.:::.: : ::: ::.:::::::::::::.:::::::.::
NP_001 KSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPI
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB3 EKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNI
:.::.::::.:.::::: ::::::::::::::::: :::::::::.::::.:::::::
NP_001 MKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNI
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB3 IPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFA
.::::::::.::::. .::::. .: :::. ::::::::: ::. :.:.: : .:::
NP_001 VPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFR-EMIPFA
280 290 300 310 320 330
270 280 290 300 310 320
pF1KB3 VVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYE
:::::.::::::::.::::: :: ::::: .::::: :::..::::.:..:..: .::.:
NP_001 VVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFE
340 350 360 370 380 390
330 340 350
pF1KB3 TYRAKRLNDNGGLPPVSVDTEESHDSNP
.::.::::. : .. ::.. :
NP_001 AYRVKRLNE--GSSAMANGMEEKEPEAPEM
400 410 420
>>NP_001106967 (OMIM: 162100,604061) septin-9 isoform d (474 aa)
initn: 1509 init1: 1119 opt: 1504 Z-score: 1706.1 bits: 324.6 E(85289): 2.7e-88
Smith-Waterman score: 1504; 64.9% identity (83.0% similar) in 353 aa overlap (4-350:124-472)
10 20 30
pF1KB3 MSKGLPETRTDAAMS---ELVPEPRPKPAVPMK
: . :.:: : ... :: .. .
NP_001 HRLPCRGLVSGFTGLRGQEEDDLAFCLATIGSDRQATEAAPSCVGDMADTPRDA-GLKQA
100 110 120 130 140 150
40 50 60 70 80
pF1KB3 PMSINSNL---LGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVS
: : : . .::.:::.:.::::.:.:: ::.::::::::::::::::.::::::..:
NP_001 PASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKIS
160 170 180 190 200 210
90 100 110 120 130 140
pF1KB3 RKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYIN
::. . . ::.::::.:::.: : ::: ::.:::::::::::::.:::::::.:: :.::
NP_001 RKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFIN
220 230 240 250 260 270
150 160 170 180 190 200
pF1KB3 EQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIA
.::::.:.::::: ::::::::::::::::: :::::::::.::::.:::::::.::::
NP_001 DQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIA
280 290 300 310 320 330
210 220 230 240 250 260
pF1KB3 KADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSD
::::.::::. .::::. .: :::. ::::::::: ::. :.:.: : .::::::::
NP_001 KADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFR-EMIPFAVVGSD
340 350 360 370 380 390
270 280 290 300 310 320
pF1KB3 KEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYETYRAK
.::::::::.::::: :: ::::: .::::: :::..::::.:..:..: .::.:.::.:
NP_001 HEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVK
400 410 420 430 440 450
330 340 350
pF1KB3 RLNDNGGLPPVSVDTEESHDSNP
:::. : .. ::.. :
NP_001 RLNE--GSSAMANGMEEKEPEAPEM
460 470
>>NP_001280624 (OMIM: 162100,604061) septin-9 isoform g (567 aa)
initn: 1509 init1: 1119 opt: 1504 Z-score: 1705.0 bits: 324.7 E(85289): 3.1e-88
Smith-Waterman score: 1504; 64.0% identity (83.5% similar) in 358 aa overlap (1-350:212-565)
10 20
pF1KB3 MSKGLPETR--TDAAMS---ELVPEPRPKP
.... :... :.:: : ... ::
NP_001 APSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDA-
190 200 210 220 230 240
30 40 50 60 70 80
pF1KB3 AVPMKPMSINSNL---LGYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLF
.. . : : : . .::.:::.:.::::.:.:: ::.::::::::::::::::.::::
NP_001 GLKQAPASRNEKAPVDFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLF
250 260 270 280 290 300
90 100 110 120 130 140
pF1KB3 KSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPI
::..:::. . . ::.::::.:::.: : ::: ::.:::::::::::::.:::::::.::
NP_001 KSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPI
310 320 330 340 350 360
150 160 170 180 190 200
pF1KB3 EKYINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNI
:.::.::::.:.::::: ::::::::::::::::: :::::::::.::::.:::::::
NP_001 MKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNI
370 380 390 400 410 420
210 220 230 240 250 260
pF1KB3 IPVIAKADTMTLEEKSEFKQRVRKELEVNGIEFYPQKEFDEDLEDKTENDKIRQESMPFA
.::::::::.::::. .::::. .: :::. ::::::::: ::. :.:.: : .:::
NP_001 VPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFR-EMIPFA
430 440 450 460 470
270 280 290 300 310 320
pF1KB3 VVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFALLRDFVIRTHLQDLKEVTHNIHYE
:::::.::::::::.::::: :: ::::: .::::: :::..::::.:..:..: .::.:
NP_001 VVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFE
480 490 500 510 520 530
330 340 350
pF1KB3 TYRAKRLNDNGGLPPVSVDTEESHDSNP
.::.::::. : .. ::.. :
NP_001 AYRVKRLNE--GSSAMANGMEEKEPEAPEM
540 550 560
350 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:40:44 2016 done: Fri Nov 4 02:40:45 2016
Total Scan time: 8.010 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]