Result of FASTA (omim) for
pF1KB3821
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3821, 423 aa
1>>>pF1KB3821 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3905+/-0.000379; mu= 16.7728+/- 0.024
mean_var=69.9112+/-13.887, 0's: 0 Z-trim(113.3): 8 B-trim: 0 in 0/56
Lambda= 0.153391
statistics sampled from 22624 (22631) to 22624 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.265), width: 16
Scan time: 8.850
The best scores are: opt bits E(85289)
NP_000131 (OMIM: 177000,612386) ferrochelatase, mi ( 423) 2871 644.6 1.4e-184
NP_001012533 (OMIM: 177000,612386) ferrochelatase, ( 429) 2849 639.7 4e-183
XP_011524184 (OMIM: 177000,612386) PREDICTED: ferr ( 351) 2389 537.9 1.5e-152
XP_016881103 (OMIM: 177000,612386) PREDICTED: ferr ( 390) 1603 364.0 3.8e-100
XP_011524183 (OMIM: 177000,612386) PREDICTED: ferr ( 396) 1581 359.1 1.1e-98
>>NP_000131 (OMIM: 177000,612386) ferrochelatase, mitoch (423 aa)
initn: 2871 init1: 2871 opt: 2871 Z-score: 3435.0 bits: 644.6 E(85289): 1.4e-184
Smith-Waterman score: 2871; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KB3 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 EQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 ILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 WQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKEC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 GVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTS
370 380 390 400 410 420
pF1KB3 QQL
:::
NP_000 QQL
>>NP_001012533 (OMIM: 177000,612386) ferrochelatase, mit (429 aa)
initn: 2441 init1: 2441 opt: 2849 Z-score: 3408.6 bits: 639.7 E(85289): 4e-183
Smith-Waterman score: 2849; 98.6% identity (98.6% similar) in 429 aa overlap (1-423:1-429)
10 20 30 40 50 60
pF1KB3 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
10 20 30 40 50 60
70 80 90 100 110
pF1KB3 QPQKR------KPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB3 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
370 380 390 400 410 420
420
pF1KB3 KSFFTSQQL
:::::::::
NP_001 KSFFTSQQL
>>XP_011524184 (OMIM: 177000,612386) PREDICTED: ferroche (351 aa)
initn: 2389 init1: 2389 opt: 2389 Z-score: 2859.7 bits: 537.9 E(85289): 1.5e-152
Smith-Waterman score: 2389; 100.0% identity (100.0% similar) in 351 aa overlap (73-423:1-351)
50 60 70 80 90 100
pF1KB3 AAVTTETAQHAQGAKPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLP
::::::::::::::::::::::::::::::
XP_011 MLNMGGPETLGDVHDFLLRLFLDRDLMTLP
10 20 30
110 120 130 140 150 160
pF1KB3 IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB3 FRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWS
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB3 TIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSA
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB3 TVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVQKVMERLEYCNPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHI
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB3 ETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLS
280 290 300 310 320 330
410 420
pF1KB3 CPLCVNPVCRETKSFFTSQQL
:::::::::::::::::::::
XP_011 CPLCVNPVCRETKSFFTSQQL
340 350
>>XP_016881103 (OMIM: 177000,612386) PREDICTED: ferroche (390 aa)
initn: 1595 init1: 1595 opt: 1603 Z-score: 1919.0 bits: 364.0 E(85289): 3.8e-100
Smith-Waterman score: 2573; 92.2% identity (92.2% similar) in 423 aa overlap (1-423:1-390)
10 20 30 40 50 60
pF1KB3 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 QPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 EQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQ-----
190 200 210 220 230
250 260 270 280 290 300
pF1KB3 ILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLV
::::::::::::::::::::::::::::::::
XP_016 ----------------------------VVNRGDPYPQEVSATVQKVMERLEYCNPYRLV
240 250 260
310 320 330 340 350 360
pF1KB3 WQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKEC
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB3 GVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTS
330 340 350 360 370 380
pF1KB3 QQL
:::
XP_016 QQL
390
>>XP_011524183 (OMIM: 177000,612386) PREDICTED: ferroche (396 aa)
initn: 1489 init1: 1165 opt: 1581 Z-score: 1892.6 bits: 359.1 E(85289): 1.1e-98
Smith-Waterman score: 2551; 90.9% identity (90.9% similar) in 429 aa overlap (1-423:1-396)
10 20 30 40 50 60
pF1KB3 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQV
10 20 30 40 50 60
70 80 90 100 110
pF1KB3 QPQKR------KPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPQKRYESNIRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 QCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYC
: ::::::::::::::::::::::::::
XP_011 Q---------------------------------VVNRGDPYPQEVSATVQKVMERLEYC
250 260
300 310 320 330 340 350
pF1KB3 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPYRLVWQSKVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQ
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB3 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRET
330 340 350 360 370 380
420
pF1KB3 KSFFTSQQL
:::::::::
XP_011 KSFFTSQQL
390
423 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:24:40 2016 done: Sat Nov 5 05:24:41 2016
Total Scan time: 8.850 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]