Result of FASTA (omim) for
pF1KB3783
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3783, 758 aa
1>>>pF1KB3783 758 - 758 aa - 758 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5663+/-0.000738; mu= 4.7394+/- 0.044
mean_var=580.8286+/-133.721, 0's: 0 Z-trim(112.9): 2201 B-trim: 360 in 1/53
Lambda= 0.053217
statistics sampled from 19164 (21956) to 19164 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.257), width: 16
Scan time: 9.980
The best scores are: opt bits E(85289)
NP_001305865 (OMIM: 601685) ribosomal protein S6 k ( 758) 5036 403.8 1.3e-111
NP_001006933 (OMIM: 601685) ribosomal protein S6 k ( 741) 4690 377.3 1.3e-103
NP_066958 (OMIM: 601685) ribosomal protein S6 kina ( 733) 4689 377.2 1.4e-103
XP_006715612 (OMIM: 601685) PREDICTED: ribosomal p ( 761) 4685 376.9 1.7e-103
NP_001305867 (OMIM: 601685) ribosomal protein S6 k ( 644) 4318 348.6 4.8e-95
NP_001305866 (OMIM: 601685) ribosomal protein S6 k ( 635) 4206 340.0 1.9e-92
NP_004577 (OMIM: 300075,300844,303600) ribosomal p ( 740) 3983 323.0 2.8e-87
XP_016885207 (OMIM: 300075,300844,303600) PREDICTE ( 711) 3982 322.9 2.9e-87
XP_016885206 (OMIM: 300075,300844,303600) PREDICTE ( 712) 3971 322.0 5.3e-87
XP_011543865 (OMIM: 300075,300844,303600) PREDICTE ( 712) 3971 322.0 5.3e-87
XP_016885205 (OMIM: 300075,300844,303600) PREDICTE ( 712) 3971 322.0 5.3e-87
XP_016885202 (OMIM: 300075,300844,303600) PREDICTE ( 712) 3971 322.0 5.3e-87
XP_016885203 (OMIM: 300075,300844,303600) PREDICTE ( 712) 3971 322.0 5.3e-87
XP_016885204 (OMIM: 300075,300844,303600) PREDICTE ( 712) 3971 322.0 5.3e-87
XP_005274630 (OMIM: 300075,300844,303600) PREDICTE ( 739) 3964 321.5 7.8e-87
XP_005274634 (OMIM: 300075,300844,303600) PREDICTE ( 710) 3963 321.4 8.1e-87
XP_011543864 (OMIM: 300075,300844,303600) PREDICTE ( 717) 3960 321.2 9.5e-87
XP_016885208 (OMIM: 300075,300844,303600) PREDICTE ( 711) 3952 320.6 1.5e-86
XP_006724570 (OMIM: 300075,300844,303600) PREDICTE ( 711) 3952 320.6 1.5e-86
XP_011543863 (OMIM: 300075,300844,303600) PREDICTE ( 718) 3949 320.3 1.7e-86
XP_011543861 (OMIM: 300075,300844,303600) PREDICTE ( 718) 3949 320.3 1.7e-86
XP_011543860 (OMIM: 300075,300844,303600) PREDICTE ( 718) 3949 320.3 1.7e-86
XP_011543859 (OMIM: 300075,300844,303600) PREDICTE ( 718) 3949 320.3 1.7e-86
XP_011543862 (OMIM: 300075,300844,303600) PREDICTE ( 718) 3949 320.3 1.7e-86
XP_011543858 (OMIM: 300075,300844,303600) PREDICTE ( 745) 3942 319.8 2.5e-86
XP_011543857 (OMIM: 300075,300844,303600) PREDICTE ( 746) 3930 318.9 4.8e-86
NP_001317370 (OMIM: 601684) ribosomal protein S6 k ( 719) 3857 313.3 2.3e-84
NP_002944 (OMIM: 601684) ribosomal protein S6 kina ( 735) 3857 313.3 2.3e-84
NP_001006666 (OMIM: 601684) ribosomal protein S6 k ( 744) 3856 313.2 2.5e-84
NP_001317441 (OMIM: 300303) ribosomal protein S6 k ( 745) 3703 301.5 8.4e-81
NP_055311 (OMIM: 300303) ribosomal protein S6 kina ( 745) 3703 301.5 8.4e-81
XP_011529219 (OMIM: 300303) PREDICTED: ribosomal p ( 745) 3703 301.5 8.4e-81
XP_016884914 (OMIM: 300303) PREDICTED: ribosomal p ( 762) 3703 301.5 8.5e-81
XP_016884912 (OMIM: 300303) PREDICTED: ribosomal p ( 762) 3703 301.5 8.5e-81
XP_016884913 (OMIM: 300303) PREDICTED: ribosomal p ( 762) 3703 301.5 8.5e-81
XP_011529221 (OMIM: 300303) PREDICTED: ribosomal p ( 642) 3383 276.8 2e-73
XP_011529222 (OMIM: 300303) PREDICTED: ribosomal p ( 624) 3283 269.1 4e-71
XP_016884915 (OMIM: 300303) PREDICTED: ribosomal p ( 506) 2569 214.1 1.1e-54
NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 1270 114.3 1.1e-24
NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 1270 114.4 1.2e-24
NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 1270 114.4 1.2e-24
NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 1268 114.2 1.3e-24
NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 1255 113.2 2.6e-24
XP_011523404 (OMIM: 608938) PREDICTED: ribosomal p ( 391) 1164 106.0 3e-22
XP_011523403 (OMIM: 608938) PREDICTED: ribosomal p ( 489) 1164 106.2 3.3e-22
XP_016880418 (OMIM: 608938) PREDICTED: ribosomal p ( 436) 1149 105.0 7e-22
NP_872198 (OMIM: 603607) ribosomal protein S6 kina ( 549) 1141 104.5 1.2e-21
NP_001309158 (OMIM: 603607) ribosomal protein S6 k ( 795) 1141 104.8 1.4e-21
NP_004746 (OMIM: 603607) ribosomal protein S6 kina ( 802) 1141 104.8 1.4e-21
NP_001287731 (OMIM: 603606) ribosomal protein S6 k ( 765) 1109 102.3 7.7e-21
>>NP_001305865 (OMIM: 601685) ribosomal protein S6 kinas (758 aa)
initn: 5036 init1: 5036 opt: 5036 Z-score: 2124.6 bits: 403.8 E(85289): 1.3e-111
Smith-Waterman score: 5036; 99.9% identity (99.9% similar) in 758 aa overlap (1-758:1-758)
10 20 30 40 50 60
pF1KB3 MPIAQLLELWKKIEVEPMEIETTEEDLNLDVGPATEDTAEEGKSDSAACKTKVAGSVEEE
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 MPIAQLLELWKKIEVEPMEIETTEEDLNLDVEPATEDTAEEGKSDSAACKTKVAGSVEEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GVVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 FTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 KPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 EIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 ITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 NFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 GNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAM
670 680 690 700 710 720
730 740 750
pF1KB3 AATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTSTRL
::::::::::::::::::::::::::::::::::::::
NP_001 AATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTSTRL
730 740 750
>>NP_001006933 (OMIM: 601685) ribosomal protein S6 kinas (741 aa)
initn: 4685 init1: 4685 opt: 4690 Z-score: 1981.2 bits: 377.3 E(85289): 1.3e-103
Smith-Waterman score: 4886; 97.6% identity (97.6% similar) in 758 aa overlap (1-758:1-741)
10 20 30 40 50 60
pF1KB3 MPIAQLLELWKKIEVEPMEIETTEEDLNLDVGPATEDTAEEGKSDSAACKTKVAGSVEEE
::::::::::::::::::::::::::::::: ::::::::: ::
NP_001 MPIAQLLELWKKIEVEPMEIETTEEDLNLDVEPATEDTAEE-----------------EE
10 20 30 40
70 80 90 100 110 120
pF1KB3 GVVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 ATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVM
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 FTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 AYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAK
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 LGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPF
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB3 KPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKV
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB3 PVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSE
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB3 EIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCT
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB3 ITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTA
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB3 NFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB3 GNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAM
650 660 670 680 690 700
730 740 750
pF1KB3 AATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTSTRL
::::::::::::::::::::::::::::::::::::::
NP_001 AATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTSTRL
710 720 730 740
>>NP_066958 (OMIM: 601685) ribosomal protein S6 kinase a (733 aa)
initn: 4686 init1: 4686 opt: 4689 Z-score: 1980.8 bits: 377.2 E(85289): 1.4e-103
Smith-Waterman score: 4689; 99.0% identity (99.6% similar) in 709 aa overlap (50-758:25-733)
20 30 40 50 60 70
pF1KB3 IETTEEDLNLDVGPATEDTAEEGKSDSAACKTKVAGSVEEEGVVKEIDISHHVKEGFEKA
:.. . .::::::::::::::::::::::
NP_066 MDLSMKKFAVRRFFSVYLRRKSRSKSSSLSRLEEEGVVKEIDISHHVKEGFEKA
10 20 30 40 50
80 90 100 110 120 130
pF1KB3 DPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 DPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILA
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB3 EVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 EVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDH
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB3 LHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRR
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB3 GHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALF
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB3 KRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTA
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB3 RTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDG
360 370 380 390 400 410
440 450 460 470 480 490
pF1KB3 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKD
420 430 440 450 460 470
500 510 520 530 540 550
pF1KB3 VYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLK
480 490 500 510 520 530
560 570 580 590 600 610
pF1KB3 PSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDI
540 550 560 570 580 590
620 630 640 650 660 670
pF1KB3 WSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 WSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLH
600 610 620 630 640 650
680 690 700 710 720 730
pF1KB3 VDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPV
660 670 680 690 700 710
740 750
pF1KB3 LSSNLAQRRGMKRLTSTRL
:::::::::::::::::::
NP_066 LSSNLAQRRGMKRLTSTRL
720 730
>>XP_006715612 (OMIM: 601685) PREDICTED: ribosomal prote (761 aa)
initn: 4685 init1: 4685 opt: 4685 Z-score: 1979.0 bits: 376.9 E(85289): 1.7e-103
Smith-Waterman score: 4685; 100.0% identity (100.0% similar) in 701 aa overlap (58-758:61-761)
30 40 50 60 70 80
pF1KB3 NLDVGPATEDTAEEGKSDSAACKTKVAGSVEEEGVVKEIDISHHVKEGFEKADPSQFELL
::::::::::::::::::::::::::::::
XP_006 RLEGLNRRAAGIKVVTIADCLHSREPETQHEEEGVVKEIDISHHVKEGFEKADPSQFELL
40 50 60 70 80 90
90 100 110 120 130 140
pF1KB3 KVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIV
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB3 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIY
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB3 RDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADW
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB3 WSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRL
280 290 300 310 320 330
330 340 350 360 370 380
pF1KB3 GAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPG
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB3 VPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIG
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB3 VGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKFV
460 470 480 490 500 510
510 520 530 540 550 560
pF1KB3 YLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRD
520 530 540 550 560 570
570 580 590 600 610 620
pF1KB3 ESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLY
580 590 600 610 620 630
630 640 650 660 670 680
pF1KB3 TMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLT
640 650 660 670 680 690
690 700 710 720 730 740
pF1KB3 AMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQR
700 710 720 730 740 750
750
pF1KB3 RGMKRLTSTRL
:::::::::::
XP_006 RGMKRLTSTRL
760
>>NP_001305867 (OMIM: 601685) ribosomal protein S6 kinas (644 aa)
initn: 4318 init1: 4318 opt: 4318 Z-score: 1827.3 bits: 348.6 E(85289): 4.8e-95
Smith-Waterman score: 4318; 100.0% identity (100.0% similar) in 644 aa overlap (115-758:1-644)
90 100 110 120 130 140
pF1KB3 ELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHP
::::::::::::::::::::::::::::::
NP_001 MKVLKKATLKVRDRVRSKMERDILAEVNHP
10 20 30
150 160 170 180 190 200
pF1KB3 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLG
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB3 IIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQS
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB3 ADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPC
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB3 NRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTD
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB3 SPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKE
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB3 DIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDG
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB3 KFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNIL
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB3 YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGI
460 470 480 490 500 510
630 640 650 660 670 680
pF1KB3 LLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQ
520 530 540 550 560 570
690 700 710 720 730 740
pF1KB3 RLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNL
580 590 600 610 620 630
750
pF1KB3 AQRRGMKRLTSTRL
::::::::::::::
NP_001 AQRRGMKRLTSTRL
640
>>NP_001305866 (OMIM: 601685) ribosomal protein S6 kinas (635 aa)
initn: 4206 init1: 4206 opt: 4206 Z-score: 1780.9 bits: 340.0 E(85289): 1.9e-92
Smith-Waterman score: 4206; 98.9% identity (99.4% similar) in 633 aa overlap (126-758:3-635)
100 110 120 130 140 150
pF1KB3 GKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQT
.:: . .:::::::::::::::::::::
NP_001 MEKDRGGAYGNRDILAEVNHPFIVKLHYAFQT
10 20 30
160 170 180 190 200 210
pF1KB3 EGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENI
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB3 LLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMF
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB3 EMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVE
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB3 EIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAH
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB3 HLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCK
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB3 RCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMR
340 350 360 370 380 390
520 530 540 550 560 570
pF1KB3 GGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESI
400 410 420 430 440 450
580 590 600 610 620 630
pF1KB3 RVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTP
460 470 480 490 500 510
640 650 660 670 680 690
pF1KB3 FANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHP
520 530 540 550 560 570
700 710 720 730 740 750
pF1KB3 WVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTS
580 590 600 610 620 630
pF1KB3 TRL
:::
NP_001 TRL
>>NP_004577 (OMIM: 300075,300844,303600) ribosomal prote (740 aa)
initn: 4009 init1: 2108 opt: 3983 Z-score: 1687.8 bits: 323.0 E(85289): 2.8e-87
Smith-Waterman score: 4007; 79.4% identity (90.4% similar) in 761 aa overlap (1-758:1-740)
10 20 30 40 50
pF1KB3 MPIAQLLELWKKIEVEPMEIETTEEDLNLDVGPATEDTAEEGKS--DSAACKTKVAGSVE
::.::: . :.:. :: .:. :.::.:.. : . .. ..:
NP_004 MPLAQLADPWQKMAVE---------------SPS--DSAENGQQIMDEPMGEEEINPQTE
10 20 30 40
60 70 80 90 100 110
pF1KB3 EEGVVKEIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVL
: .. ::: :.:::::: ::::::::::::::::::.::::::.:..:::: ::::::::
NP_004 EVSI-KEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB3 KKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE
::::::::::::.:::::::.:::::::::::::::::::::::::::::::::::::::
NP_004 KKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 VMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHD
::::::::::::::::::::::::::::::::::::::::::::::.::::::::.:::.
NP_004 VMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB3 KRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILK
:.:::::::.::::::::::::::::::::::::::::::::.::::::::::::..:::
NP_004 KKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB3 AKLGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKP
:::::::::: ::::::: :::::: :::::: ::::::::: :: ::::: :::.::.:
NP_004 AKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHP
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB3 PFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLH
:::::.:::::::.:::::::.:: ::::.:::::::.::::::::: . .. .: ..
NP_004 PFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVA--ITSDDESQAMQ
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB3 KVPVHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDP
: :: :::::: :.:.::::::.:::::::::::::::.::::. :.::::::::::::
NP_004 TVGVHSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDP
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB3 SEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVL
.::::::::::::::::::::::::::.::.: :::.::::::.::::..::::::: ::
NP_004 TEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFFSEREASAVL
470 480 490 500 510 520
540 550 560 570 580 590
pF1KB3 CTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCY
:::::..:::.::::::::::::::: ::::.:::::.::::::::::: :::::::::
NP_004 FTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCY
530 540 550 560 570 580
600 610 620 630 640 650
pF1KB3 TANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYAL
:::::::::::::::::::::::::.::::::.:.::::::::::::::::::::::..:
NP_004 TANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSL
590 600 610 620 630 640
660 670 680 690 700 710
pF1KB3 SGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYLSPNQLSRQDV-HLVK
::: :.:.::.:::.::::::::::::::: ::.:::.:. . : ::.:::. ::::
NP_004 SGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVK
650 660 670 680 690 700
720 730 740 750
pF1KB3 GAMAATYFALNRTPQAPRLEPVLSSNLAQRRGMKRLTSTRL
::::::: ::::. :.: :::: :.::::::.:..::: :
NP_004 GAMAATYSALNRN-QSPVLEPVGRSTLAQRRGIKKITSTAL
710 720 730 740
>>XP_016885207 (OMIM: 300075,300844,303600) PREDICTED: r (711 aa)
initn: 3967 init1: 2119 opt: 3982 Z-score: 1687.5 bits: 322.9 E(85289): 2.9e-87
Smith-Waterman score: 3982; 83.8% identity (93.8% similar) in 704 aa overlap (56-758:11-711)
30 40 50 60 70 80
pF1KB3 DLNLDVGPATEDTAEEGKSDSAACKTKVAGSVEEEGVVKEIDISHHVKEGFEKADPSQFE
:..:: .::: :.:::::: :::::::::
XP_016 MFKFLSFRVRSIQEEVSIKEIAITHHVKEGHEKADPSQFE
10 20 30 40
90 100 110 120 130 140
pF1KB3 LLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPF
:::::::::.::::::.:..:::: ::::::::::::::::::::.:::::::.::::::
XP_016 LLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPF
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB3 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB3 IYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSA
:::::::::::::::::::.::::::::.:::.:.:::::::.:::::::::::::::::
XP_016 IYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSA
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB3 DWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCN
:::::::::::::::.::::::::::::..::::::::::::: ::::::: :::::: :
XP_016 DWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPAN
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB3 RLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDS
::::: ::::::::: :: ::::: :::.::.::::::.:::::::.:::::::.:: ::
XP_016 RLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDS
290 300 310 320 330 340
390 400 410 420 430 440
pF1KB3 PGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKED
::.:::::::.::::::::: . .. .: .. : :: :::::: :.:.::::::.:::
XP_016 PGIPPSANAHQLFRGFSFVA--ITSDDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKED
350 360 370 380 390
450 460 470 480 490 500
pF1KB3 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK
::::::::::::.::::. :.::::::::::::.::::::::::::::::::::::::::
XP_016 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK
400 410 420 430 440 450
510 520 530 540 550 560
pF1KB3 FVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILY
.::.: :::.::::::.::::..::::::: :: :::::..:::.:::::::::::::::
XP_016 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY
460 470 480 490 500 510
570 580 590 600 610 620
pF1KB3 RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGIL
::::.:::::.::::::::::: ::::::::::::::::::::::::::::::::::.:
XP_016 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL
520 530 540 550 560 570
630 640 650 660 670 680
pF1KB3 LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQR
:::::.:.::::::::::::::::::::::..:::: :.:.::.:::.::::::::::::
XP_016 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR
580 590 600 610 620 630
690 700 710 720 730 740
pF1KB3 LTAMQVLKHPWVVNREYLSPNQLSRQDV-HLVKGAMAATYFALNRTPQAPRLEPVLSSNL
::: ::.:::.:. . : ::.:::. ::::::::::: ::::. :.: :::: :.:
XP_016 LTAALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRN-QSPVLEPVGRSTL
640 650 660 670 680 690
750
pF1KB3 AQRRGMKRLTSTRL
:::::.:..::: :
XP_016 AQRRGIKKITSTAL
700 710
>>XP_016885206 (OMIM: 300075,300844,303600) PREDICTED: r (712 aa)
initn: 3956 init1: 2108 opt: 3971 Z-score: 1683.0 bits: 322.0 E(85289): 5.3e-87
Smith-Waterman score: 3971; 84.0% identity (93.7% similar) in 701 aa overlap (59-758:15-712)
30 40 50 60 70 80
pF1KB3 LDVGPATEDTAEEGKSDSAACKTKVAGSVEEEGVVKEIDISHHVKEGFEKADPSQFELLK
:: .::: :.:::::: ::::::::::::
XP_016 MDEPMGEEEINPQTEEVSIKEIAITHHVKEGHEKADPSQFELLK
10 20 30 40
90 100 110 120 130 140
pF1KB3 VLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK
::::::.::::::.:..:::: ::::::::::::::::::::.:::::::.:::::::::
XP_016 VLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVK
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB3 LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYR
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB3 DLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWW
::::::::::::::::.::::::::.:::.:.:::::::.::::::::::::::::::::
XP_016 DLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWW
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB3 SFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRLG
::::::::::::.::::::::::::..::::::::::::: ::::::: :::::: ::::
XP_016 SFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLG
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB3 AGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGV
:: ::::::::: :: ::::: :::.::.::::::.:::::::.:::::::.:: ::::.
XP_016 AGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGI
290 300 310 320 330 340
390 400 410 420 430 440
pF1KB3 PPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIGV
:::::::.::::::::: . .. .: .. : :: :::::: :.:.::::::.::::::
XP_016 PPSANAHQLFRGFSFVA--ITSDDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKEDIGV
350 360 370 380 390 400
450 460 470 480 490 500
pF1KB3 GSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKFVY
:::::::::.::::. :.::::::::::::.::::::::::::::::::::::::::.::
XP_016 GSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVY
410 420 430 440 450 460
510 520 530 540 550 560
pF1KB3 LVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDE
.: :::.::::::.::::..::::::: :: :::::..:::.::::::::::::::: ::
XP_016 VVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDE
470 480 490 500 510 520
570 580 590 600 610 620
pF1KB3 SGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYT
::.:::::.::::::::::: ::::::::::::::::::::::::::::::::::.::::
XP_016 SGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYT
530 540 550 560 570 580
630 640 650 660 670 680
pF1KB3 MLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTA
::.:.::::::::::::::::::::::..:::: :.:.::.:::.:::::::::::::::
XP_016 MLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTA
590 600 610 620 630 640
690 700 710 720 730 740
pF1KB3 MQVLKHPWVVNREYLSPNQLSRQDV-HLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQR
::.:::.:. . : ::.:::. ::::::::::: ::::. :.: :::: :.::::
XP_016 ALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRN-QSPVLEPVGRSTLAQR
650 660 670 680 690 700
750
pF1KB3 RGMKRLTSTRL
::.:..::: :
XP_016 RGIKKITSTAL
710
>>XP_011543865 (OMIM: 300075,300844,303600) PREDICTED: r (712 aa)
initn: 3956 init1: 2108 opt: 3971 Z-score: 1683.0 bits: 322.0 E(85289): 5.3e-87
Smith-Waterman score: 3971; 84.0% identity (93.7% similar) in 701 aa overlap (59-758:15-712)
30 40 50 60 70 80
pF1KB3 LDVGPATEDTAEEGKSDSAACKTKVAGSVEEEGVVKEIDISHHVKEGFEKADPSQFELLK
:: .::: :.:::::: ::::::::::::
XP_011 MDEPMGEEEINPQTEEVSIKEIAITHHVKEGHEKADPSQFELLK
10 20 30 40
90 100 110 120 130 140
pF1KB3 VLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVK
::::::.::::::.:..:::: ::::::::::::::::::::.:::::::.:::::::::
XP_011 VLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVK
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB3 LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYR
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB3 DLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWW
::::::::::::::::.::::::::.:::.:.:::::::.::::::::::::::::::::
XP_011 DLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWW
170 180 190 200 210 220
270 280 290 300 310 320
pF1KB3 SFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRLG
::::::::::::.::::::::::::..::::::::::::: ::::::: :::::: ::::
XP_011 SFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLG
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB3 AGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGV
:: ::::::::: :: ::::: :::.::.::::::.:::::::.:::::::.:: ::::.
XP_011 AGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGI
290 300 310 320 330 340
390 400 410 420 430 440
pF1KB3 PPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKEDIGV
:::::::.::::::::: . .. .: .. : :: :::::: :.:.::::::.::::::
XP_011 PPSANAHQLFRGFSFVA--ITSDDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKEDIGV
350 360 370 380 390 400
450 460 470 480 490 500
pF1KB3 GSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKFVY
:::::::::.::::. :.::::::::::::.::::::::::::::::::::::::::.::
XP_011 GSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVY
410 420 430 440 450 460
510 520 530 540 550 560
pF1KB3 LVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDE
.: :::.::::::.::::..::::::: :: :::::..:::.::::::::::::::: ::
XP_011 VVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDE
470 480 490 500 510 520
570 580 590 600 610 620
pF1KB3 SGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYT
::.:::::.::::::::::: ::::::::::::::::::::::::::::::::::.::::
XP_011 SGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYT
530 540 550 560 570 580
630 640 650 660 670 680
pF1KB3 MLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTA
::.:.::::::::::::::::::::::..:::: :.:.::.:::.:::::::::::::::
XP_011 MLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTA
590 600 610 620 630 640
690 700 710 720 730 740
pF1KB3 MQVLKHPWVVNREYLSPNQLSRQDV-HLVKGAMAATYFALNRTPQAPRLEPVLSSNLAQR
::.:::.:. . : ::.:::. ::::::::::: ::::. :.: :::: :.::::
XP_011 ALVLRHPWIVHWDQLPQYQLNRQDAPHLVKGAMAATYSALNRN-QSPVLEPVGRSTLAQR
650 660 670 680 690 700
750
pF1KB3 RGMKRLTSTRL
::.:..::: :
XP_011 RGIKKITSTAL
710
758 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:11:03 2016 done: Thu Nov 3 21:11:05 2016
Total Scan time: 9.980 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]