Result of FASTA (omim) for
pF1KB3758
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3758, 594 aa
1>>>pF1KB3758 594 - 594 aa - 594 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.9588+/-0.000374; mu= 0.2246+/- 0.023
mean_var=322.1462+/-64.760, 0's: 0 Z-trim(122.7): 34 B-trim: 98 in 1/58
Lambda= 0.071457
statistics sampled from 41346 (41380) to 41346 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.485), width: 16
Scan time: 13.330
The best scores are: opt bits E(85289)
NP_001073340 (OMIM: 600947) huntingtin-associated ( 594) 3918 417.6 5.7e-116
NP_001073339 (OMIM: 600947) huntingtin-associated ( 602) 3892 415.0 3.7e-115
NP_817084 (OMIM: 600947) huntingtin-associated pro ( 619) 2653 287.2 1.1e-76
>>NP_001073340 (OMIM: 600947) huntingtin-associated prot (594 aa)
initn: 3918 init1: 3918 opt: 3918 Z-score: 2203.0 bits: 417.6 E(85289): 5.7e-116
Smith-Waterman score: 3918; 99.3% identity (99.8% similar) in 594 aa overlap (1-594:1-594)
10 20 30 40 50 60
pF1KB3 MRPRRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGTQF
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_001 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAEELRTSLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAEELRTSLRR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 MISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIMRGEDFTPA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 EELVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNVVTSALEASGL
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNVVTSALEASGL
490 500 510 520 530 540
550 560 570 580 590
pF1KB3 GPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCRSSCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCRSSCR
550 560 570 580 590
>>NP_001073339 (OMIM: 600947) huntingtin-associated prot (602 aa)
initn: 2676 init1: 2676 opt: 3892 Z-score: 2188.4 bits: 415.0 E(85289): 3.7e-115
Smith-Waterman score: 3892; 98.0% identity (98.5% similar) in 602 aa overlap (1-594:1-602)
10 20 30 40 50 60
pF1KB3 MRPRRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGTQF
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
130 140 150 160 170 180
190 200 210 220 230
pF1KB3 LEE--------LLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALL
::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEVCTAFLIQLLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 GSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSAKEEILYLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAH
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 PCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCDAPKLISQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILEC
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB3 VEQFLEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAE
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEQFSEASQQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB3 ELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQVRGFEAEEGLMLAADIM
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB3 RGEDFTPAEELVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNVVT
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGWEEVELELDEATRMNVVT
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB3 SALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGECPHGALPAASRTSCRSS
550 560 570 580 590 600
pF1KB3 CR
::
NP_001 CR
>>NP_817084 (OMIM: 600947) huntingtin-associated protein (619 aa)
initn: 3904 init1: 2631 opt: 2653 Z-score: 1498.0 bits: 287.2 E(85289): 1.1e-76
Smith-Waterman score: 3858; 95.3% identity (95.8% similar) in 619 aa overlap (1-594:1-619)
10 20 30 40 50 60
pF1KB3 MRPRRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGTQF
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_817 MRPKRLGRCCAGSRLGPGDPAALTCAPSPSASPAPEPSAQPQARGTGQRVGSRATSGSQF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 LSEARTGARPASEAGAKAGARRPSAFSAIQGDVRSMPDNSDAPWTRFVFQGPFGSRATGR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 GTGKAAGIWKTPAAYVGRRPGVSGPERAAFIRELEEALCPNLPPPVKKITQEDVKVMLYL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 LEELLPPVWESVTYGMVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 YLRHQVNLRDELLQLYSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_817 SQEALLHQHHCPQLEALQEKLRLLEEENHQLREEASQLDTLEDEEQMLILECVEQFSEAS
310 320 330 340 350 360
370 380 390 400
pF1KB3 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRM--------------------
::::::::::::::::::::::::::::::::::::::::
NP_817 QQMAELSEVLVLRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQM
370 380 390 400 410 420
410 420 430 440 450
pF1KB3 -----ETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 QLQEEETLPGFQETLAEELRTSLRRMISDPVYFMERNYEMPRGDTSSLRYDFRYSEDREQ
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB3 VRGFEAEEGLMLAADIMRGEDFTPAEELVPQEELGAAKKVPAEEGVMEEAELVSEETEGW
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_817 VRGFEAEEGLMLAADIMRGEDFTPAEEFVPQEELGAAKKVPAEEGVMEEAELVSEETEGW
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB3 EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 EEVELELDEATRMNVVTSALEASGLGPSHLDMNYVLQQLANWQDAHYRRQLRWKMLQKGE
550 560 570 580 590 600
580 590
pF1KB3 CPHGALPAASRTSCRSSCR
:::::::::::::::::::
NP_817 CPHGALPAASRTSCRSSCR
610
594 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:40:08 2016 done: Fri Nov 4 02:40:10 2016
Total Scan time: 13.330 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]