Result of FASTA (omim) for
pF1KB3738
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3738, 357 aa
1>>>pF1KB3738 357 - 357 aa - 357 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0522+/-0.000345; mu= 17.5757+/- 0.021
mean_var=68.1203+/-14.116, 0's: 0 Z-trim(113.6): 66 B-trim: 749 in 1/50
Lambda= 0.155395
statistics sampled from 23017 (23089) to 23017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.271), width: 16
Scan time: 7.570
The best scores are: opt bits E(85289)
NP_003095 (OMIM: 182500) sorbitol dehydrogenase [H ( 357) 2390 544.9 1e-154
NP_000658 (OMIM: 103700) alcohol dehydrogenase 1A ( 375) 207 55.5 2.2e-07
NP_000659 (OMIM: 103720,103780) alcohol dehydrogen ( 375) 198 53.5 9.1e-07
NP_000660 (OMIM: 103730,103780,168600) alcohol deh ( 375) 197 53.3 1.1e-06
NP_000661 (OMIM: 103740) alcohol dehydrogenase 4 i ( 380) 182 49.9 1.1e-05
XP_016863204 (OMIM: 103740) PREDICTED: alcohol deh ( 387) 182 49.9 1.1e-05
NP_001293101 (OMIM: 103740) alcohol dehydrogenase ( 399) 182 49.9 1.1e-05
NP_001293100 (OMIM: 103740) alcohol dehydrogenase ( 399) 182 49.9 1.1e-05
XP_016863203 (OMIM: 103740) PREDICTED: alcohol deh ( 406) 182 49.9 1.2e-05
XP_016863202 (OMIM: 103740) PREDICTED: alcohol deh ( 406) 182 49.9 1.2e-05
NP_000664 (OMIM: 600086) alcohol dehydrogenase cla ( 386) 177 48.8 2.4e-05
NP_001159976 (OMIM: 600086) alcohol dehydrogenase ( 394) 177 48.8 2.5e-05
XP_011529890 (OMIM: 103730,103780,168600) PREDICTE ( 341) 171 47.4 5.6e-05
NP_001273579 (OMIM: 103720,103780) alcohol dehydro ( 335) 170 47.2 6.4e-05
XP_011529891 (OMIM: 103730,103780,168600) PREDICTE ( 335) 168 46.7 8.8e-05
NP_000663 (OMIM: 103735) alcohol dehydrogenase 6 i ( 368) 159 44.7 0.00038
NP_001095940 (OMIM: 103735) alcohol dehydrogenase ( 375) 159 44.7 0.00039
NP_000662 (OMIM: 103710) alcohol dehydrogenase cla ( 374) 155 43.8 0.00072
XP_016855857 (OMIM: 123691) PREDICTED: quinone oxi ( 192) 148 42.1 0.0013
NP_001128231 (OMIM: 123691) quinone oxidoreductase ( 192) 148 42.1 0.0013
XP_005270548 (OMIM: 123691) PREDICTED: quinone oxi ( 192) 148 42.1 0.0013
NP_006364 (OMIM: 604631) synaptic vesicle membrane ( 393) 149 42.5 0.0019
>>NP_003095 (OMIM: 182500) sorbitol dehydrogenase [Homo (357 aa)
initn: 2390 init1: 2390 opt: 2390 Z-score: 2898.7 bits: 544.9 E(85289): 1e-154
Smith-Waterman score: 2390; 99.7% identity (100.0% similar) in 357 aa overlap (1-357:1-357)
10 20 30 40 50 60
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 GCKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_003 GCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMTTVPLLHAAIREVDIKGVFRY
250 260 270 280 290 300
310 320 330 340 350
pF1KB3 CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
310 320 330 340 350
>>NP_000658 (OMIM: 103700) alcohol dehydrogenase 1A [Hom (375 aa)
initn: 264 init1: 131 opt: 207 Z-score: 253.4 bits: 55.5 E(85289): 2.2e-07
Smith-Waterman score: 372; 27.9% identity (56.1% similar) in 358 aa overlap (22-348:24-373)
10 20 30 40 50
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIG
.:. . : .:: ..: .:::::.: : :
NP_000 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVS----G
10 20 30 40 50
60 70 80 90 100
pF1KB3 NFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRV---AIEP-GAPR--ENDE--FC----
.... :..:::::.: ::.:: .: .::::.: :: : : .: : .:
NP_000 TMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKND
60 70 80 90 100 110
110 120 130 140 150
pF1KB3 ---KMGRYNLSPSIFFCATPPDDG--NLCRFYKHNAA---FCYKLPDNVTFEEGALIE-P
.: . . : : : : .. : ..... :. .:. ::
NP_000 VSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB3 LSVGI-HACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEI
.:.: : . :: : : : : .:. ... :: :::.....:.. ...::::.
NP_000 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKEL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB3 GADLVL--QISKESPQEIARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GTLVL
:: . : :. ::. ... .: . . ..: : ...:.. . . :: :.
NP_000 GATECINPQDYKKPIQEVLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVI
240 250 260 270 280 290
280 290 300 310 320
pF1KB3 VGL---GSEMTTVPLLHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFP
::. ..... :.: . : : : :. . : .. . .:. .. :.:: .:
NP_000 VGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLP
300 310 320 330 340 350
330 340 350
pF1KB3 LEKALEAFETFKKGLGLKIMLKCDPSDQNP
.:: :.:. ...: ... .:
NP_000 FEKINEGFDLLHSGKSIRTILMF
360 370
>>NP_000659 (OMIM: 103720,103780) alcohol dehydrogenase (375 aa)
initn: 262 init1: 139 opt: 198 Z-score: 242.5 bits: 53.5 E(85289): 9.1e-07
Smith-Waterman score: 362; 27.4% identity (55.6% similar) in 358 aa overlap (22-348:24-373)
10 20 30 40 50
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIG
.:. . : :: ..: .:::: .: : :
NP_000 MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVS----G
10 20 30 40 50
60 70 80 90 100
pF1KB3 NFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVA--IEP--GAPR--ENDE--FC---K
:... :..:::::.: ::.:: .: .::::.: . : : : .: : .:
NP_000 NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKND
60 70 80 90 100 110
110 120 130 140 150
pF1KB3 MG--RYNLSPSI--FFCATPP-----DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIE-P
.: : .:. . : : : ... .. . :. .:. ::
NP_000 LGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB3 LSVGI-HACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEI
.:.: : . :: : : : : .:. ... :: :::.....:.. ...::::.
NP_000 FSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKEL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB3 GADLVL--QISKESPQEIARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GTLVL
:: . : :. ::. ... .: . . ..: : ...:.. . . :: :.
NP_000 GATECINPQDYKKPIQEVLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVI
240 250 260 270 280 290
280 290 300 310 320
pF1KB3 VGL---GSEMTTVPLLHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFP
::. ..... :.: . : . : :. . : .. . .:. .. :.:: .:
NP_000 VGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLP
300 310 320 330 340 350
330 340 350
pF1KB3 LEKALEAFETFKKGLGLKIMLKCDPSDQNP
.:: :.:. ...: ... .:
NP_000 FEKINEGFDLLHSGKSIRTVLTF
360 370
>>NP_000660 (OMIM: 103730,103780,168600) alcohol dehydro (375 aa)
initn: 260 init1: 139 opt: 197 Z-score: 241.3 bits: 53.3 E(85289): 1.1e-06
Smith-Waterman score: 362; 27.7% identity (57.3% similar) in 358 aa overlap (22-348:24-373)
10 20 30 40 50
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIG
.:. . : .:: ..: ..::: :: : :
NP_000 MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----G
10 20 30 40 50
60 70 80 90 100
pF1KB3 NFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVA--IEP--GAPR--ENDE--FC---K
:... :..:::::.: ::.:: .: .::::.: . : : : .: : .:
NP_000 NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKND
60 70 80 90 100 110
110 120 130 140 150
pF1KB3 MG--RYNLSPSI--FFCATPPDDG--NLCRFYKHNAA---FCYKLPDNVTFEEGALIE-P
.: : .:. . : :. : .. : ..... :. .:. ::
NP_000 LGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCG
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB3 LSVGI-HACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEI
.:.: : . . :: : : : : .:. ... :: :::.....:.. ...::::.
NP_000 FSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKEL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB3 GADLVL--QISKESPQEIARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GTLVL
:: . : :. ::. ... .: . . ..: : ...:.. . . :: :.
NP_000 GATECINPQDYKKPIQEVLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVI
240 250 260 270 280 290
280 290 300 310 320
pF1KB3 VGL---GSEMTTVPLLHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFP
::. ..... :.: . : : : :. .. : .. . .:. .. :.:. .:
NP_000 VGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILP
300 310 320 330 340 350
330 340 350
pF1KB3 LEKALEAFETFKKGLGLKIMLKCDPSDQNP
.:: :.:. ...: ... .:
NP_000 FEKINEGFDLLRSGKSIRTVLTF
360 370
>>NP_000661 (OMIM: 103740) alcohol dehydrogenase 4 isofo (380 aa)
initn: 255 init1: 134 opt: 182 Z-score: 223.0 bits: 49.9 E(85289): 1.1e-05
Smith-Waterman score: 344; 25.5% identity (55.6% similar) in 369 aa overlap (20-348:22-378)
10 20 30 40 50
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIG
: .:. . : .:: ... ....: .:. . :
NP_000 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 NFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF
. :...::::.: ::..: .: ..::::.: : :: .:. .. :::
NP_000 ---LAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPLYAP-----LCRKCKFCLSPLTN
70 80 90 100 110
120 130 140
pF1KB3 FCA------TPPDDGNL---------CR------FYKHNAAFCY---------KLPDNVT
.:. .: .: .: :. :. .. : :. :...
NP_000 LCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDAN
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB3 FEEGALIE-PLSVGIHAC-RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS
.:. :. .:.: : . :: : : : : .:. ... :: ::.... :..
NP_000 LERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB3 ATRLSKAKEIGA-DLVLQISKESP-QEIARKVEGQLGCKPEVTIECTGAEASIQAGIYAT
. .. ::: .:: : . . ..: ::. .: : . ...:.:. ...:.. :
NP_000 SEKFVKAKALGATDCLNPRDLHKPIQEVI--IELTKG-GVDFALDCAGGSETMKAALDCT
240 250 260 270 280
270 280 290 300 310
pF1KB3 RSG-GTLVLVGL--GSE-MTTVPLLHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNV
.: :. ...:. ::. .: : : .. . : .. .. : .. .:. :.
NP_000 TAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNL
290 300 310 320 330 340
320 330 340 350
pF1KB3 KPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
:::: .:..: :::. ...: ... .:
NP_000 DALVTHTLPFDKISEAFDLMNQGKSVRTILIF
350 360 370 380
>>XP_016863204 (OMIM: 103740) PREDICTED: alcohol dehydro (387 aa)
initn: 248 init1: 134 opt: 182 Z-score: 222.9 bits: 49.9 E(85289): 1.1e-05
Smith-Waterman score: 337; 25.7% identity (55.2% similar) in 362 aa overlap (20-341:22-371)
10 20 30 40 50
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIG
: .:. . : .:: ... ....: .:. . :
XP_016 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 NFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIF
. :...::::.: ::..: .: ..::::.: : :: .:. .. :::
XP_016 ---LAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPLYAP-----LCRKCKFCLSPLTN
70 80 90 100 110
120 130 140
pF1KB3 FCA------TPPDDGNL---------CR------FYKHNAAFCY---------KLPDNVT
.:. .: .: .: :. :. .. : :. :...
XP_016 LCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDAN
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB3 FEEGALIE-PLSVGIHAC-RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLS
.:. :. .:.: : . :: : : : : .:. ... :: ::.... :..
XP_016 LERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDIN
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB3 ATRLSKAKEIGA-DLVLQISKESP-QEIARKVEGQLGCKPEVTIECTGAEASIQAGIYAT
. .. ::: .:: : . . ..: ::. .: : . ...:.:. ...:.. :
XP_016 SEKFVKAKALGATDCLNPRDLHKPIQEVI--IELTKG-GVDFALDCAGGSETMKAALDCT
240 250 260 270 280
270 280 290 300 310
pF1KB3 RSG-GTLVLVGL--GSE-MTTVPLLHAAIREVD--IKGVFRYCNTWPVAISMLASKSVNV
.: :. ...:. ::. .: : : .. . : .. .. : .. .:. :.
XP_016 TAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNL
290 300 310 320 330 340
320 330 340 350
pF1KB3 KPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
:::: .:..: :::. ...:
XP_016 DALVTHTLPFDKISEAFDLMNQGKSYRRSENSDYSKTKT
350 360 370 380
>>NP_001293101 (OMIM: 103740) alcohol dehydrogenase 4 is (399 aa)
initn: 255 init1: 134 opt: 182 Z-score: 222.7 bits: 49.9 E(85289): 1.1e-05
Smith-Waterman score: 344; 25.5% identity (55.6% similar) in 369 aa overlap (20-348:41-397)
10 20 30 40
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDV
: .:. . : .:: ... ....: .:.
NP_001 QRCKTHLFSSNYLTQVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDA
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB3 HYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMG
. : . :...::::.: ::..: .: ..::::.: : :: .:.
NP_001 TVIDSKFEG---LAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPLYAP-----LCRKC
80 90 100 110 120
110 120 130 140
pF1KB3 RYNLSPSIFFCA------TPPDDGNL---------CR------FYKHNAAFCY-------
.. ::: .:. .: .: .: :. :. .. :
NP_001 KFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDIN
130 140 150 160 170 180
150 160 170 180 190
pF1KB3 --KLPDNVTFEEGALIE-PLSVGIHAC-RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGA
:. :....:. :. .:.: : . :: : : : : .:. ... :: ::
NP_001 LAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB3 AQVVVTDLSATRLSKAKEIGA-DLVLQISKESP-QEIARKVEGQLGCKPEVTIECTGAEA
.... :... .. ::: .:: : . . ..: ::. .: : . ...:.:.
NP_001 SRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI--IELTKG-GVDFALDCAGGSE
250 260 270 280 290
260 270 280 290 300
pF1KB3 SIQAGIYATRSG-GTLVLVGL--GSE-MTTVPLLHAAIREVD--IKGVFRYCNTWPVAIS
...:.. : .: :. ...:. ::. .: : : .. . : .. .. : ..
NP_001 TMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVT
300 310 320 330 340 350
310 320 330 340 350
pF1KB3 MLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
.:. :. :::: .:..: :::. ...: ... .:
NP_001 DYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF
360 370 380 390
>>NP_001293100 (OMIM: 103740) alcohol dehydrogenase 4 is (399 aa)
initn: 255 init1: 134 opt: 182 Z-score: 222.7 bits: 49.9 E(85289): 1.1e-05
Smith-Waterman score: 344; 25.5% identity (55.6% similar) in 369 aa overlap (20-348:41-397)
10 20 30 40
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDV
: .:. . : .:: ... ....: .:.
NP_001 QRCKTHLFSSNYLTQVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDA
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB3 HYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMG
. : . :...::::.: ::..: .: ..::::.: : :: .:.
NP_001 TVIDSKFEG---LAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPLYAP-----LCRKC
80 90 100 110 120
110 120 130 140
pF1KB3 RYNLSPSIFFCA------TPPDDGNL---------CR------FYKHNAAFCY-------
.. ::: .:. .: .: .: :. :. .. :
NP_001 KFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDIN
130 140 150 160 170 180
150 160 170 180 190
pF1KB3 --KLPDNVTFEEGALIE-PLSVGIHAC-RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGA
:. :....:. :. .:.: : . :: : : : : .:. ... :: ::
NP_001 LAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB3 AQVVVTDLSATRLSKAKEIGA-DLVLQISKESP-QEIARKVEGQLGCKPEVTIECTGAEA
.... :... .. ::: .:: : . . ..: ::. .: : . ...:.:.
NP_001 SRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI--IELTKG-GVDFALDCAGGSE
250 260 270 280 290
260 270 280 290 300
pF1KB3 SIQAGIYATRSG-GTLVLVGL--GSE-MTTVPLLHAAIREVD--IKGVFRYCNTWPVAIS
...:.. : .: :. ...:. ::. .: : : .. . : .. .. : ..
NP_001 TMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVT
300 310 320 330 340 350
310 320 330 340 350
pF1KB3 MLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
.:. :. :::: .:..: :::. ...: ... .:
NP_001 DYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSVRTILIF
360 370 380 390
>>XP_016863203 (OMIM: 103740) PREDICTED: alcohol dehydro (406 aa)
initn: 248 init1: 134 opt: 182 Z-score: 222.6 bits: 49.9 E(85289): 1.2e-05
Smith-Waterman score: 337; 25.7% identity (55.2% similar) in 362 aa overlap (20-341:41-390)
10 20 30 40
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDV
: .:. . : .:: ... ....: .:.
XP_016 QRCKTHLFSSNYLTQVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDA
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB3 HYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMG
. : . :...::::.: ::..: .: ..::::.: : :: .:.
XP_016 TVIDSKFEG---LAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPLYAP-----LCRKC
80 90 100 110 120
110 120 130 140
pF1KB3 RYNLSPSIFFCA------TPPDDGNL---------CR------FYKHNAAFCY-------
.. ::: .:. .: .: .: :. :. .. :
XP_016 KFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDIN
130 140 150 160 170 180
150 160 170 180 190
pF1KB3 --KLPDNVTFEEGALIE-PLSVGIHAC-RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGA
:. :....:. :. .:.: : . :: : : : : .:. ... :: ::
XP_016 LAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB3 AQVVVTDLSATRLSKAKEIGA-DLVLQISKESP-QEIARKVEGQLGCKPEVTIECTGAEA
.... :... .. ::: .:: : . . ..: ::. .: : . ...:.:.
XP_016 SRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI--IELTKG-GVDFALDCAGGSE
250 260 270 280 290
260 270 280 290 300
pF1KB3 SIQAGIYATRSG-GTLVLVGL--GSE-MTTVPLLHAAIREVD--IKGVFRYCNTWPVAIS
...:.. : .: :. ...:. ::. .: : : .. . : .. .. : ..
XP_016 TMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVT
300 310 320 330 340 350
310 320 330 340 350
pF1KB3 MLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
.:. :. :::: .:..: :::. ...:
XP_016 DYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSYRRSENSDYSKTKT
360 370 380 390 400
>>XP_016863202 (OMIM: 103740) PREDICTED: alcohol dehydro (406 aa)
initn: 248 init1: 134 opt: 182 Z-score: 222.6 bits: 49.9 E(85289): 1.2e-05
Smith-Waterman score: 337; 25.7% identity (55.2% similar) in 362 aa overlap (20-341:41-390)
10 20 30 40
pF1KB3 MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDV
: .:. . : .:: ... ....: .:.
XP_016 QRCKTHLFSSNYLTQVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDA
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB3 HYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMG
. : . :...::::.: ::..: .: ..::::.: : :: .:.
XP_016 TVIDSKFEG---LAFPVIVGHEAAGIVESIGPGVTNVKPGDKV-IPLYAP-----LCRKC
80 90 100 110 120
110 120 130 140
pF1KB3 RYNLSPSIFFCA------TPPDDGNL---------CR------FYKHNAAFCY-------
.. ::: .:. .: .: .: :. :. .. :
XP_016 KFCLSPLTNLCGKISNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDIN
130 140 150 160 170 180
150 160 170 180 190
pF1KB3 --KLPDNVTFEEGALIE-PLSVGIHAC-RRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGA
:. :....:. :. .:.: : . :: : : : : .:. ... :: ::
XP_016 LAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGA
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB3 AQVVVTDLSATRLSKAKEIGA-DLVLQISKESP-QEIARKVEGQLGCKPEVTIECTGAEA
.... :... .. ::: .:: : . . ..: ::. .: : . ...:.:.
XP_016 SRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVI--IELTKG-GVDFALDCAGGSE
250 260 270 280 290
260 270 280 290 300
pF1KB3 SIQAGIYATRSG-GTLVLVGL--GSE-MTTVPLLHAAIREVD--IKGVFRYCNTWPVAIS
...:.. : .: :. ...:. ::. .: : : .. . : .. .. : ..
XP_016 TMKAALDCTTAGWGSCTFIGVAAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVT
300 310 320 330 340 350
310 320 330 340 350
pF1KB3 MLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP
.:. :. :::: .:..: :::. ...:
XP_016 DYKNKKFNLDALVTHTLPFDKISEAFDLMNQGKSYRRSENSDYSKTKT
360 370 380 390 400
357 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:21:07 2016 done: Sat Nov 5 05:21:08 2016
Total Scan time: 7.570 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]