Result of FASTA (omim) for
pF1KB3725
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3725, 1375 aa
1>>>pF1KB3725 1375 - 1375 aa - 1375 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5076+/-0.000656; mu= 4.6929+/- 0.040
mean_var=580.4221+/-124.528, 0's: 0 Z-trim(116.1): 1865 B-trim: 33 in 1/52
Lambda= 0.053236
statistics sampled from 24510 (27062) to 24510 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.317), width: 16
Scan time: 15.160
The best scores are: opt bits E(85289)
NP_005914 (OMIM: 602448) mitogen-activated protein (1374) 9002 709.1 5.7e-203
XP_016866362 (OMIM: 602448) PREDICTED: mitogen-act (1483) 9002 709.1 5.9e-203
XP_016866361 (OMIM: 602448) PREDICTED: mitogen-act (1484) 8990 708.2 1.1e-202
XP_016866360 (OMIM: 602448) PREDICTED: mitogen-act (1493) 8867 698.8 7.8e-200
XP_016866359 (OMIM: 602448) PREDICTED: mitogen-act (1494) 8855 697.8 1.5e-199
XP_016866366 (OMIM: 602448) PREDICTED: mitogen-act (1181) 7696 608.7 8.2e-173
XP_011534141 (OMIM: 602448) PREDICTED: mitogen-act (1286) 7691 608.3 1.1e-172
XP_016866365 (OMIM: 602448) PREDICTED: mitogen-act (1191) 7561 598.3 1.1e-169
XP_016866363 (OMIM: 602448) PREDICTED: mitogen-act (1458) 4940 397.1 4.8e-109
NP_001001671 (OMIM: 300820) mitogen-activated prot (1313) 4082 331.2 3.1e-89
XP_016866364 (OMIM: 602448) PREDICTED: mitogen-act (1447) 3681 300.4 6.1e-80
XP_011543809 (OMIM: 300820) PREDICTED: mitogen-act (1324) 3569 291.8 2.3e-77
XP_011543810 (OMIM: 300820) PREDICTED: mitogen-act (1295) 3504 286.8 7.1e-76
NP_001284538 (OMIM: 604468) mitogen-activated prot (1280) 3185 262.3 1.7e-68
NP_004663 (OMIM: 604468) mitogen-activated protein (1288) 3181 262.0 2.1e-68
XP_016885000 (OMIM: 300820) PREDICTED: mitogen-act ( 825) 2930 242.4 1.1e-62
XP_016858261 (OMIM: 604468) PREDICTED: mitogen-act ( 801) 2458 206.1 8.5e-52
XP_011543812 (OMIM: 300820) PREDICTED: mitogen-act ( 871) 2425 203.6 5.2e-51
XP_016858260 (OMIM: 604468) PREDICTED: mitogen-act ( 869) 1978 169.3 1.1e-40
XP_011543813 (OMIM: 300820) PREDICTED: mitogen-act ( 748) 1968 168.4 1.8e-40
NP_001317360 (OMIM: 602539) mitogen-activated prot ( 622) 583 61.9 1.7e-08
NP_002392 (OMIM: 602539) mitogen-activated protein ( 626) 583 61.9 1.7e-08
XP_005257433 (OMIM: 602539) PREDICTED: mitogen-act ( 653) 583 61.9 1.7e-08
NP_976226 (OMIM: 602539) mitogen-activated protein ( 657) 583 62.0 1.7e-08
NP_006600 (OMIM: 609487) mitogen-activated protein ( 619) 567 60.7 3.9e-08
NP_001278887 (OMIM: 602425) mitogen-activated prot (1061) 568 61.1 4.9e-08
XP_016866358 (OMIM: 602425) PREDICTED: mitogen-act (1517) 568 61.4 5.9e-08
XP_005267046 (OMIM: 602425) PREDICTED: mitogen-act (1554) 568 61.4 5.9e-08
NP_006715 (OMIM: 602425) mitogen-activated protein (1558) 568 61.4 5.9e-08
NP_001288001 (OMIM: 602425) mitogen-activated prot (1604) 568 61.4 6e-08
NP_005913 (OMIM: 602425) mitogen-activated protein (1608) 568 61.4 6e-08
XP_016864974 (OMIM: 600982,613762) PREDICTED: mito (1349) 564 61.0 6.8e-08
XP_016864973 (OMIM: 600982,613762) PREDICTED: mito (1375) 564 61.0 6.9e-08
NP_005912 (OMIM: 600982,613762) mitogen-activated (1512) 564 61.1 7.2e-08
XP_016873337 (OMIM: 602590) PREDICTED: serine/thre ( 545) 500 55.4 1.3e-06
XP_016873336 (OMIM: 602590) PREDICTED: serine/thre ( 545) 500 55.4 1.3e-06
NP_002567 (OMIM: 602590) serine/threonine-protein ( 545) 500 55.4 1.3e-06
XP_016873338 (OMIM: 602590) PREDICTED: serine/thre ( 545) 500 55.4 1.3e-06
XP_016873339 (OMIM: 602590) PREDICTED: serine/thre ( 545) 500 55.4 1.3e-06
XP_016873335 (OMIM: 602590) PREDICTED: serine/thre ( 545) 500 55.4 1.3e-06
XP_016869247 (OMIM: 605030) PREDICTED: serine/thre ( 456) 495 54.9 1.6e-06
NP_006272 (OMIM: 605030) serine/threonine-protein ( 491) 495 55.0 1.6e-06
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519) 495 55.0 1.7e-06
XP_011515553 (OMIM: 605030) PREDICTED: serine/thre ( 522) 495 55.0 1.7e-06
XP_016869246 (OMIM: 605030) PREDICTED: serine/thre ( 524) 495 55.0 1.7e-06
XP_011515550 (OMIM: 605030) PREDICTED: serine/thre ( 576) 495 55.1 1.7e-06
XP_016869245 (OMIM: 605030) PREDICTED: serine/thre ( 580) 495 55.1 1.8e-06
NP_001311255 (OMIM: 300142,300558) serine/threonin ( 544) 492 54.8 2e-06
XP_016885050 (OMIM: 300142,300558) PREDICTED: seri ( 544) 492 54.8 2e-06
NP_002569 (OMIM: 300142,300558) serine/threonine-p ( 544) 492 54.8 2e-06
>>NP_005914 (OMIM: 602448) mitogen-activated protein kin (1374 aa)
initn: 6519 init1: 6519 opt: 9002 Z-score: 3765.0 bits: 709.1 E(85289): 5.7e-203
Smith-Waterman score: 9002; 99.8% identity (99.8% similar) in 1375 aa overlap (1-1375:1-1374)
10 20 30 40 50 60
pF1KB3 MSTEADEGITFSVPPFAPSGFCTIPEGGICRRGGAAAVGEGEEHQLPPPPPGSFWNVESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSTEADEGITFSVPPFAPSGFCTIPEGGICRRGGAAAVGEGEEHQLPPPPPGSFWNVESA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AAPGIGCPAATSSSSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAPGIGCPAATSSSSATRGRGSSVGGGSRRTTVAYVINEASQGQLVVAESEALQSLREAC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ETVGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ETVGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 IILYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IILYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 RRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 KAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 FLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 EWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTEPDCKKFFEMVNTITEEKGRS
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_005 EWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 TEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 PLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 GFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 PEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 YLRSISLPVPVLVEDTSSSSEYGSVSPDDTELKVDPFSFKTRAKSCGERDVKGIRTLFLG
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_005 YLRSISLPVPVLVEDTSSSSEYGSVSPD-TELKVDPFSFKTRAKSCGERDVKGIRTLFLG
970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB3 IPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKIVRNLMESLAQGAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKIVRNLMESLAQGAEE
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KB3 PKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVN
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KB3 KVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVEDDHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVEDDHE
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KB3 EQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEEL
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KB3 VRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNTEDSELTDWLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNTEDSELTDWLRV
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370
pF1KB3 NGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT
1320 1330 1340 1350 1360 1370
>>XP_016866362 (OMIM: 602448) PREDICTED: mitogen-activat (1483 aa)
initn: 6519 init1: 6519 opt: 9002 Z-score: 3764.7 bits: 709.1 E(85289): 5.9e-203
Smith-Waterman score: 9002; 99.8% identity (99.8% similar) in 1375 aa overlap (1-1375:110-1483)
10 20 30
pF1KB3 MSTEADEGITFSVPPFAPSGFCTIPEGGIC
::::::::::::::::::::::::::::::
XP_016 RRARSSPELWLARRCGWAGDAAAVAARPGEMSTEADEGITFSVPPFAPSGFCTIPEGGIC
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB3 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB3 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB3 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB3 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
320 330 340 350 360 370
280 290 300 310 320 330
pF1KB3 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
380 390 400 410 420 430
340 350 360 370 380 390
pF1KB3 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
440 450 460 470 480 490
400 410 420 430 440 450
pF1KB3 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
500 510 520 530 540 550
460 470 480 490 500 510
pF1KB3 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
560 570 580 590 600 610
520 530 540 550 560 570
pF1KB3 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
620 630 640 650 660 670
580 590 600 610 620 630
pF1KB3 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
680 690 700 710 720 730
640 650 660 670 680 690
pF1KB3 DDFQIYFCTEPDCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
740 750 760 770 780 790
700 710 720 730 740 750
pF1KB3 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
800 810 820 830 840 850
760 770 780 790 800 810
pF1KB3 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
860 870 880 890 900 910
820 830 840 850 860 870
pF1KB3 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
920 930 940 950 960 970
880 890 900 910 920 930
pF1KB3 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
980 990 1000 1010 1020 1030
940 950 960 970 980 990
pF1KB3 DLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPDDT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 DLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPD-T
1040 1050 1060 1070 1080 1090
1000 1010 1020 1030 1040 1050
pF1KB3 ELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSE
1100 1110 1120 1130 1140 1150
1060 1070 1080 1090 1100 1110
pF1KB3 RRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATT
1160 1170 1180 1190 1200 1210
1120 1130 1140 1150 1160 1170
pF1KB3 LSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITI
1220 1230 1240 1250 1260 1270
1180 1190 1200 1210 1220 1230
pF1KB3 LVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSST
1280 1290 1300 1310 1320 1330
1240 1250 1260 1270 1280 1290
pF1KB3 VSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQ
1340 1350 1360 1370 1380 1390
1300 1310 1320 1330 1340 1350
pF1KB3 PIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDL
1400 1410 1420 1430 1440 1450
1360 1370
pF1KB3 KCLRLRGGMLCTLWKAIIDFRNKQT
:::::::::::::::::::::::::
XP_016 KCLRLRGGMLCTLWKAIIDFRNKQT
1460 1470 1480
>>XP_016866361 (OMIM: 602448) PREDICTED: mitogen-activat (1484 aa)
initn: 8817 init1: 8817 opt: 8990 Z-score: 3759.7 bits: 708.2 E(85289): 1.1e-202
Smith-Waterman score: 8990; 99.7% identity (99.7% similar) in 1376 aa overlap (1-1375:110-1484)
10 20 30
pF1KB3 MSTEADEGITFSVPPFAPSGFCTIPEGGIC
::::::::::::::::::::::::::::::
XP_016 RRARSSPELWLARRCGWAGDAAAVAARPGEMSTEADEGITFSVPPFAPSGFCTIPEGGIC
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB3 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB3 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB3 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB3 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
320 330 340 350 360 370
280 290 300 310 320 330
pF1KB3 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
380 390 400 410 420 430
340 350 360 370 380 390
pF1KB3 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
440 450 460 470 480 490
400 410 420 430 440 450
pF1KB3 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
500 510 520 530 540 550
460 470 480 490 500 510
pF1KB3 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
560 570 580 590 600 610
520 530 540 550 560 570
pF1KB3 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
620 630 640 650 660 670
580 590 600 610 620 630
pF1KB3 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
680 690 700 710 720 730
640 650 660 670 680 690
pF1KB3 DDFQIYFCTEPDCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
740 750 760 770 780 790
700 710 720 730 740 750
pF1KB3 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
800 810 820 830 840 850
760 770 780 790 800 810
pF1KB3 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
860 870 880 890 900 910
820 830 840 850 860 870
pF1KB3 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
920 930 940 950 960 970
880 890 900 910 920 930
pF1KB3 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
980 990 1000 1010 1020 1030
940 950 960 970 980
pF1KB3 DLLVDEFLKVSSKKKKTQPKLSALSAGSN-EYLRSISLPVPVLVEDTSSSSEYGSVSPDD
::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_016 DLLVDEFLKVSSKKKKTQPKLSALSAGSNAEYLRSISLPVPVLVEDTSSSSEYGSVSPD-
1040 1050 1060 1070 1080 1090
990 1000 1010 1020 1030 1040
pF1KB3 TELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDS
1100 1110 1120 1130 1140 1150
1050 1060 1070 1080 1090 1100
pF1KB3 ERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIAT
1160 1170 1180 1190 1200 1210
1110 1120 1130 1140 1150 1160
pF1KB3 TLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAIT
1220 1230 1240 1250 1260 1270
1170 1180 1190 1200 1210 1220
pF1KB3 ILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSS
1280 1290 1300 1310 1320 1330
1230 1240 1250 1260 1270 1280
pF1KB3 TVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKS
1340 1350 1360 1370 1380 1390
1290 1300 1310 1320 1330 1340
pF1KB3 QPIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDD
1400 1410 1420 1430 1440 1450
1350 1360 1370
pF1KB3 LKCLRLRGGMLCTLWKAIIDFRNKQT
::::::::::::::::::::::::::
XP_016 LKCLRLRGGMLCTLWKAIIDFRNKQT
1460 1470 1480
>>XP_016866360 (OMIM: 602448) PREDICTED: mitogen-activat (1493 aa)
initn: 6519 init1: 6519 opt: 8867 Z-score: 3708.6 bits: 698.8 E(85289): 7.8e-200
Smith-Waterman score: 8867; 99.8% identity (99.8% similar) in 1356 aa overlap (1-1356:110-1464)
10 20 30
pF1KB3 MSTEADEGITFSVPPFAPSGFCTIPEGGIC
::::::::::::::::::::::::::::::
XP_016 RRARSSPELWLARRCGWAGDAAAVAARPGEMSTEADEGITFSVPPFAPSGFCTIPEGGIC
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB3 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB3 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB3 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB3 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
320 330 340 350 360 370
280 290 300 310 320 330
pF1KB3 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
380 390 400 410 420 430
340 350 360 370 380 390
pF1KB3 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
440 450 460 470 480 490
400 410 420 430 440 450
pF1KB3 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
500 510 520 530 540 550
460 470 480 490 500 510
pF1KB3 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
560 570 580 590 600 610
520 530 540 550 560 570
pF1KB3 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
620 630 640 650 660 670
580 590 600 610 620 630
pF1KB3 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
680 690 700 710 720 730
640 650 660 670 680 690
pF1KB3 DDFQIYFCTEPDCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
740 750 760 770 780 790
700 710 720 730 740 750
pF1KB3 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
800 810 820 830 840 850
760 770 780 790 800 810
pF1KB3 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
860 870 880 890 900 910
820 830 840 850 860 870
pF1KB3 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
920 930 940 950 960 970
880 890 900 910 920 930
pF1KB3 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
980 990 1000 1010 1020 1030
940 950 960 970 980 990
pF1KB3 DLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPDDT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 DLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPD-T
1040 1050 1060 1070 1080 1090
1000 1010 1020 1030 1040 1050
pF1KB3 ELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSE
1100 1110 1120 1130 1140 1150
1060 1070 1080 1090 1100 1110
pF1KB3 RRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATT
1160 1170 1180 1190 1200 1210
1120 1130 1140 1150 1160 1170
pF1KB3 LSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITI
1220 1230 1240 1250 1260 1270
1180 1190 1200 1210 1220 1230
pF1KB3 LVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSST
1280 1290 1300 1310 1320 1330
1240 1250 1260 1270 1280 1290
pF1KB3 VSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQ
1340 1350 1360 1370 1380 1390
1300 1310 1320 1330 1340 1350
pF1KB3 PIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDL
1400 1410 1420 1430 1440 1450
1360 1370
pF1KB3 KCLRLRGGMLCTLWKAIIDFRNKQT
::::::
XP_016 KCLRLRYHFSFCCHYGKSTRQISKSLSIFPGWVSN
1460 1470 1480 1490
>>XP_016866359 (OMIM: 602448) PREDICTED: mitogen-activat (1494 aa)
initn: 8682 init1: 8682 opt: 8855 Z-score: 3703.7 bits: 697.8 E(85289): 1.5e-199
Smith-Waterman score: 8855; 99.7% identity (99.7% similar) in 1357 aa overlap (1-1356:110-1465)
10 20 30
pF1KB3 MSTEADEGITFSVPPFAPSGFCTIPEGGIC
::::::::::::::::::::::::::::::
XP_016 RRARSSPELWLARRCGWAGDAAAVAARPGEMSTEADEGITFSVPPFAPSGFCTIPEGGIC
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB3 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB3 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB3 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB3 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
320 330 340 350 360 370
280 290 300 310 320 330
pF1KB3 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
380 390 400 410 420 430
340 350 360 370 380 390
pF1KB3 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
440 450 460 470 480 490
400 410 420 430 440 450
pF1KB3 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
500 510 520 530 540 550
460 470 480 490 500 510
pF1KB3 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
560 570 580 590 600 610
520 530 540 550 560 570
pF1KB3 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
620 630 640 650 660 670
580 590 600 610 620 630
pF1KB3 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
680 690 700 710 720 730
640 650 660 670 680 690
pF1KB3 DDFQIYFCTEPDCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
740 750 760 770 780 790
700 710 720 730 740 750
pF1KB3 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
800 810 820 830 840 850
760 770 780 790 800 810
pF1KB3 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
860 870 880 890 900 910
820 830 840 850 860 870
pF1KB3 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
920 930 940 950 960 970
880 890 900 910 920 930
pF1KB3 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
980 990 1000 1010 1020 1030
940 950 960 970 980
pF1KB3 DLLVDEFLKVSSKKKKTQPKLSALSAGSN-EYLRSISLPVPVLVEDTSSSSEYGSVSPDD
::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_016 DLLVDEFLKVSSKKKKTQPKLSALSAGSNAEYLRSISLPVPVLVEDTSSSSEYGSVSPD-
1040 1050 1060 1070 1080 1090
990 1000 1010 1020 1030 1040
pF1KB3 TELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDS
1100 1110 1120 1130 1140 1150
1050 1060 1070 1080 1090 1100
pF1KB3 ERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIAT
1160 1170 1180 1190 1200 1210
1110 1120 1130 1140 1150 1160
pF1KB3 TLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAIT
1220 1230 1240 1250 1260 1270
1170 1180 1190 1200 1210 1220
pF1KB3 ILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSS
1280 1290 1300 1310 1320 1330
1230 1240 1250 1260 1270 1280
pF1KB3 TVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKS
1340 1350 1360 1370 1380 1390
1290 1300 1310 1320 1330 1340
pF1KB3 QPIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDD
1400 1410 1420 1430 1440 1450
1350 1360 1370
pF1KB3 LKCLRLRGGMLCTLWKAIIDFRNKQT
:::::::
XP_016 LKCLRLRYHFSFCCHYGKSTRQISKSLSIFPGWVSN
1460 1470 1480 1490
>>XP_016866366 (OMIM: 602448) PREDICTED: mitogen-activat (1181 aa)
initn: 7523 init1: 7523 opt: 7696 Z-score: 3223.5 bits: 608.7 E(85289): 8.2e-173
Smith-Waterman score: 7696; 99.5% identity (99.7% similar) in 1182 aa overlap (195-1375:1-1181)
170 180 190 200 210 220
pF1KB3 LFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVY
..::::::::::::::::::::::::::::
XP_016 MQEIICQKNTMCTGNYTFVPYMITPHNKVY
10 20 30
230 240 250 260 270 280
pF1KB3 CCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKAR
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB3 NLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFD
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB3 LASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDS
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB3 NFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLG
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB3 KKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHF
280 290 300 310 320 330
530 540 550 560 570 580
pF1KB3 VKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEK
340 350 360 370 380 390
590 600 610 620 630 640
pF1KB3 TISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTEPDCK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 TISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCK
400 410 420 430 440 450
650 660 670 680 690 700
pF1KB3 KFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQV
460 470 480 490 500 510
710 720 730 740 750 760
pF1KB3 RIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSA
520 530 540 550 560 570
770 780 790 800 810 820
pF1KB3 LLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFG
580 590 600 610 620 630
830 840 850 860 870 880
pF1KB3 TSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYEL
640 650 660 670 680 690
890 900 910 920 930 940
pF1KB3 GEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKK
700 710 720 730 740 750
950 960 970 980 990 1000
pF1KB3 KKTQPKLSALSAGSN-EYLRSISLPVPVLVEDTSSSSEYGSVSPDDTELKVDPFSFKTRA
::::::::::::::: ::::::::::::::::::::::::::::: ::::::::::::::
XP_016 KKTQPKLSALSAGSNAEYLRSISLPVPVLVEDTSSSSEYGSVSPD-TELKVDPFSFKTRA
760 770 780 790 800
1010 1020 1030 1040 1050 1060
pF1KB3 KSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQ
810 820 830 840 850 860
1070 1080 1090 1100 1110 1120
pF1KB3 DKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSH
870 880 890 900 910 920
1130 1140 1150 1160 1170 1180
pF1KB3 GISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLAS
930 940 950 960 970 980
1190 1200 1210 1220 1230 1240
pF1KB3 ESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLN
990 1000 1010 1020 1030 1040
1250 1260 1270 1280 1290 1300
pF1KB3 VQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLN
1050 1060 1070 1080 1090 1100
1310 1320 1330 1340 1350 1360
pF1KB3 SSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTL
1110 1120 1130 1140 1150 1160
1370
pF1KB3 WKAIIDFRNKQT
::::::::::::
XP_016 WKAIIDFRNKQT
1170 1180
>>XP_011534141 (OMIM: 602448) PREDICTED: mitogen-activat (1286 aa)
initn: 7813 init1: 7518 opt: 7691 Z-score: 3221.1 bits: 608.3 E(85289): 1.1e-172
Smith-Waterman score: 7691; 99.6% identity (99.7% similar) in 1175 aa overlap (1-1174:110-1283)
10 20 30
pF1KB3 MSTEADEGITFSVPPFAPSGFCTIPEGGIC
::::::::::::::::::::::::::::::
XP_011 RRARSSPELWLARRCGWAGDAAAVAARPGEMSTEADEGITFSVPPFAPSGFCTIPEGGIC
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB3 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB3 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB3 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB3 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
320 330 340 350 360 370
280 290 300 310 320 330
pF1KB3 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
380 390 400 410 420 430
340 350 360 370 380 390
pF1KB3 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
440 450 460 470 480 490
400 410 420 430 440 450
pF1KB3 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
500 510 520 530 540 550
460 470 480 490 500 510
pF1KB3 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
560 570 580 590 600 610
520 530 540 550 560 570
pF1KB3 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
620 630 640 650 660 670
580 590 600 610 620 630
pF1KB3 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
680 690 700 710 720 730
640 650 660 670 680 690
pF1KB3 DDFQIYFCTEPDCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
740 750 760 770 780 790
700 710 720 730 740 750
pF1KB3 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
800 810 820 830 840 850
760 770 780 790 800 810
pF1KB3 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
860 870 880 890 900 910
820 830 840 850 860 870
pF1KB3 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
920 930 940 950 960 970
880 890 900 910 920 930
pF1KB3 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
980 990 1000 1010 1020 1030
940 950 960 970 980
pF1KB3 DLLVDEFLKVSSKKKKTQPKLSALSAGSN-EYLRSISLPVPVLVEDTSSSSEYGSVSPDD
::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_011 DLLVDEFLKVSSKKKKTQPKLSALSAGSNAEYLRSISLPVPVLVEDTSSSSEYGSVSPD-
1040 1050 1060 1070 1080 1090
990 1000 1010 1020 1030 1040
pF1KB3 TELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDS
1100 1110 1120 1130 1140 1150
1050 1060 1070 1080 1090 1100
pF1KB3 ERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIAT
1160 1170 1180 1190 1200 1210
1110 1120 1130 1140 1150 1160
pF1KB3 TLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAIT
1220 1230 1240 1250 1260 1270
1170 1180 1190 1200 1210 1220
pF1KB3 ILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSS
::::.
XP_011 ILVPDHIL
1280
>>XP_016866365 (OMIM: 602448) PREDICTED: mitogen-activat (1191 aa)
initn: 7388 init1: 7388 opt: 7561 Z-score: 3167.4 bits: 598.3 E(85289): 1.1e-169
Smith-Waterman score: 7561; 99.5% identity (99.7% similar) in 1163 aa overlap (195-1356:1-1162)
170 180 190 200 210 220
pF1KB3 LFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVY
..::::::::::::::::::::::::::::
XP_016 MQEIICQKNTMCTGNYTFVPYMITPHNKVY
10 20 30
230 240 250 260 270 280
pF1KB3 CCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKAR
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB3 NLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFD
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB3 LASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDS
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB3 NFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLG
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB3 KKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHF
280 290 300 310 320 330
530 540 550 560 570 580
pF1KB3 VKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEK
340 350 360 370 380 390
590 600 610 620 630 640
pF1KB3 TISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTEPDCK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 TISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCK
400 410 420 430 440 450
650 660 670 680 690 700
pF1KB3 KFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQV
460 470 480 490 500 510
710 720 730 740 750 760
pF1KB3 RIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSA
520 530 540 550 560 570
770 780 790 800 810 820
pF1KB3 LLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFG
580 590 600 610 620 630
830 840 850 860 870 880
pF1KB3 TSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYEL
640 650 660 670 680 690
890 900 910 920 930 940
pF1KB3 GEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKK
700 710 720 730 740 750
950 960 970 980 990 1000
pF1KB3 KKTQPKLSALSAGSN-EYLRSISLPVPVLVEDTSSSSEYGSVSPDDTELKVDPFSFKTRA
::::::::::::::: ::::::::::::::::::::::::::::: ::::::::::::::
XP_016 KKTQPKLSALSAGSNAEYLRSISLPVPVLVEDTSSSSEYGSVSPD-TELKVDPFSFKTRA
760 770 780 790 800
1010 1020 1030 1040 1050 1060
pF1KB3 KSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQ
810 820 830 840 850 860
1070 1080 1090 1100 1110 1120
pF1KB3 DKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSH
870 880 890 900 910 920
1130 1140 1150 1160 1170 1180
pF1KB3 GISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLAS
930 940 950 960 970 980
1190 1200 1210 1220 1230 1240
pF1KB3 ESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLN
990 1000 1010 1020 1030 1040
1250 1260 1270 1280 1290 1300
pF1KB3 VQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLN
1050 1060 1070 1080 1090 1100
1310 1320 1330 1340 1350 1360
pF1KB3 SSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRYHFSFCC
1110 1120 1130 1140 1150 1160
1370
pF1KB3 WKAIIDFRNKQT
XP_016 HYGKSTRQISKSLSIFPGWVSN
1170 1180 1190
>>XP_016866363 (OMIM: 602448) PREDICTED: mitogen-activat (1458 aa)
initn: 4767 init1: 4767 opt: 4940 Z-score: 2078.7 bits: 397.1 E(85289): 4.8e-109
Smith-Waterman score: 8538; 97.1% identity (97.1% similar) in 1357 aa overlap (1-1356:110-1429)
10 20 30
pF1KB3 MSTEADEGITFSVPPFAPSGFCTIPEGGIC
::::::::::::::::::::::::::::::
XP_016 RRARSSPELWLARRCGWAGDAAAVAARPGEMSTEADEGITFSVPPFAPSGFCTIPEGGIC
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB3 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPGIGCPAATSSSSATRGRGSSVGGGSRR
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB3 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVAYVINEASQGQLVVAESEALQSLREACETVGATLETLHFGKLDFGETTVLDRFYNAD
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB3 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSLKEIICQKNTMCTGNY
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB3 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQ
320 330 340 350 360 370
280 290 300 310 320 330
pF1KB3 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSI
380 390 400 410 420 430
340 350 360 370 380 390
pF1KB3 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMY
440 450 460 470 480 490
400 410 420 430 440 450
pF1KB3 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSF
500 510 520 530 540 550
460 470 480 490 500 510
pF1KB3 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVIQASEKLFKLKTPAWY
560 570 580 590 600 610
520 530 540 550 560 570
pF1KB3 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVEATKTDVTVVRFP----------
620 630 640 650 660
580 590 600 610 620 630
pF1KB3 QPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
::::::::::::::::::::::::::::::::::
XP_016 --------------------------KGIHEWNFSASSVRGVSISKFEERCCFLYVLHNS
670 680 690 700
640 650 660 670 680 690
pF1KB3 DDFQIYFCTEPDCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCESDLLEYDYEYDENGDRVVLGKGT
710 720 730 740 750 760
700 710 720 730 740 750
pF1KB3 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFI
770 780 790 800 810 820
760 770 780 790 800 810
pF1KB3 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVL
830 840 850 860 870 880
820 830 840 850 860 870
pF1KB3 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCT
890 900 910 920 930 940
880 890 900 910 920 930
pF1KB3 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACAN
950 960 970 980 990 1000
940 950 960 970 980
pF1KB3 DLLVDEFLKVSSKKKKTQPKLSALSAGSN-EYLRSISLPVPVLVEDTSSSSEYGSVSPDD
::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_016 DLLVDEFLKVSSKKKKTQPKLSALSAGSNAEYLRSISLPVPVLVEDTSSSSEYGSVSPD-
1010 1020 1030 1040 1050 1060
990 1000 1010 1020 1030 1040
pF1KB3 TELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDS
1070 1080 1090 1100 1110 1120
1050 1060 1070 1080 1090 1100
pF1KB3 ERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRATLHRILTEDQDKIVRNLMESLAQGAEEPKLKWEHITTLIASLREFVRSTDRKIIAT
1130 1140 1150 1160 1170 1180
1110 1120 1130 1140 1150 1160
pF1KB3 TLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAIT
1190 1200 1210 1220 1230 1240
1170 1180 1190 1200 1210 1220
pF1KB3 ILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILVPELRPHFSLASESDTADQEDLDVEDDHEEQPSNQTVRRPQAVIEDAVATSGVSTLSS
1250 1260 1270 1280 1290 1300
1230 1240 1250 1260 1270 1280
pF1KB3 TVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKS
1310 1320 1330 1340 1350 1360
1290 1300 1310 1320 1330 1340
pF1KB3 QPIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDD
1370 1380 1390 1400 1410 1420
1350 1360 1370
pF1KB3 LKCLRLRGGMLCTLWKAIIDFRNKQT
:::::::
XP_016 LKCLRLRYHFSFCCHYGKSTRQISKSLSIFPGWVSN
1430 1440 1450
>>NP_001001671 (OMIM: 300820) mitogen-activated protein (1313 aa)
initn: 3482 init1: 1755 opt: 4082 Z-score: 1723.0 bits: 331.2 E(85289): 3.1e-89
Smith-Waterman score: 5097; 58.6% identity (80.8% similar) in 1347 aa overlap (35-1374:10-1304)
10 20 30 40 50 60
pF1KB3 ADEGITFSVPPFAPSGFCTIPEGGICRRGGAAAVGEGEEHQLPPPPPGSFWNVESAAAPG
:.:.: . : ::::: ::.::.:.
NP_001 MESGGGNAPAGALGAASESPQCPPPPG----VEGAAGPA
10 20 30
70 80 90 100 110 120
pF1KB3 IGCPAATSSSSATRGRGSSVGGGSRRTTVA-YVINEASQGQLVVA-ESEALQSLREACET
:: ...... :.: : ::: ::. : :: .:.::: . . :. : : : .:::.
NP_001 EPDGAAEGAAGGS-GEGES-GGGPRRALRAVYVRSESSQGGAAGGPEAGARQCLLRACEA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 VGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNII
:: : .. ::.::::::.::: ::.::.:::.:::. :::::::::::::::.::::.:
NP_001 EGAHLTSVPFGELDFGETAVLDAFYDADVAVVDMSDVSRQPSLFYHLGVRESFDMANNVI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB3 LYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNF
:: ::..:. :::... :::: .::: :.::..:: .::.:. .. .: ::::.
NP_001 LYHDTDADTALSLKDMVTQKNTASSGNYYFIPYIVTPCADYFCCESDAQRRASEYMQPNW
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB3 ELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQR
. .:::.:.:::::::.::: ...: :..:..::::::::. : :.::: :::::. :
NP_001 DNILGPLCMPLVDRFISLLKDIHVTSCVYYKETLLNDIRKAREKYQGEELAKELARIKLR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB3 VDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRR
.:: ::::.::.::::::::::::::..:::::::: ::: :::..:..:::::::::::
NP_001 MDNTEVLTSDIIINLLLSYRDIQDYDAMVKLVETLEMLPTCDLADQHNIKFHYAFALNRR
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB3 NLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFKKA
: ::: :::.::. ..:: . . ::.:: ::::::.::::. : ::: . :..:.
NP_001 NSTGDREKALQIMLQVLQSCDHPGPDMFCLCGRIYKDIFLDSDCKDDTSRDSAIEWYRKG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB3 FESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFL
:: . .: :::: ::::..::.:::.:.::::.::.:.::::.::.:::...::.:: :.
NP_001 FELQSSLYSGINLAVLLIVAGQQFETSLELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFF
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB3 GASVLANDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFW
..:.::.: ...::.:.::::: :.:::.:.:...:. ..: : :. .:: ..::
NP_001 SVSMLAHDVGKAVQAAERLFKLKPPVWYLRSLVQNLLLIRRFKKTIIEHS-PRQERLNFW
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB3 MDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEW
.:.. :::. .. .:::::..::::.:::::.:::::.::.:.:.::: : . : .:::
NP_001 LDIIFEATNEVTNGLRFPVLVIEPTKVYQPSYVSINNEAEERTVSLWHVSPTEMKQMHEW
520 530 540 550 560 570
610 620 630 640 650 660
pF1KB3 NFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTEPDCKKFFEMVNT-ITEEKGRST
::.:::..:.:.:::.:::::::: ::::::::: :: .:..:: .:. ::. : ..
NP_001 NFTASSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEEQCSRFFSLVKEMITNTAGSTV
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB3 E-EGDCESDLLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
: ::. ..: :::.:..: ::.::::::::::::::::::::::::::::::::::::::
NP_001 ELEGETDGDTLEYEYDHDANGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB3 PLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTI
::::::::::.:::.:::::::: ::::.:::::::::::::::::::::::.: : ::
NP_001 PLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMK--EPTI
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB3 GFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFT
::::::::::::::.::::::::::::::.::::::.:::::::::::::.::::::::
NP_001 KFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETFT
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB3 GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVH
::::::::::::.:::::: :::::::::::::::.::::.::::::::::::::::.:
NP_001 GTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEPQAAMFKVGMFKIH
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB3 PEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNE
:::::..::::.::::.:::::: ::: . .:: . ::. .: ::.. .. .:
NP_001 PEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFLRQVNKGKKNR-----IAFKPSE
880 890 900 910 920
970 980 990 1000 1010
pF1KB3 YLRSISLPVPVLVED-TSSSSEYGSVSPDDTELKVDPFSFKTRAKSCGERDVKGIRTLFL
:.. : .:. : ..::::.:::::: .. . : . .::: : : .:
NP_001 GPRGVVLALPTQGEPMATSSSEHGSVSPD-SDAQPDALFERTRA----PRHHLG---HLL
930 940 950 960 970
1020 1030 1040 1050 1060 1070
pF1KB3 GIPDEN--FEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKIVRNLMESLAQG
..:::. .::.. :::..:.:.:.::::::::: :..:: :.:.... ::.: .::.
NP_001 SVPDESSALEDRGLASSPEDRDQGLFLLRKDSERRAILYKILWEEQNQVASNLQECVAQS
980 990 1000 1010 1020 1030
1080 1090 1100 1110 1120 1130
pF1KB3 AEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQD
.:: .:. :: .:. ::.:.:: .....:::.::::..::::: .:::...:::::::
NP_001 SEELHLSVGHIKQIIGILRDFIRSPEHRVMATTISKLKVDLDFDSSSISQIHLVLFGFQD
1040 1050 1060 1070 1080 1090
1140 1150 1160 1170 1180 1190
pF1KB3 AVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVED
::::.:::: :.::::::.:.:::.:::.:.:::.:::: :: . :.. .:. :...
NP_001 AVNKILRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELRAHFEPTCETEGVDK---DMDE
1100 1110 1120 1130 1140 1150
1200 1210 1220 1230 1240 1250
pF1KB3 DHEEQPSNQTVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLL
.: : : .. ....: .. :..:::... ::::::
NP_001 AEEGYP-------P----------------ATGPGQEAQPHQQHLSLQLGELRQETNRLL
1160 1170 1180 1190
1260 1270 1280 1290 1300 1310
pF1KB3 EELVRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNTEDSELTDW
:.::.::.: : ::....:.: ::. ::.:: . : : :. . : : :.:: ::
NP_001 EHLVEKEREYQNLLRQTLEQKTQELYHLQLKLKSNCITENPA---GPYGQRT-DKELIDW
1200 1210 1220 1230 1240
1320 1330 1340 1350 1360 1370
pF1KB3 LRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT
::..::: :: ... : ::: :.: .:..::. ::::::.:: ::.:. ..: :
NP_001 LRLQGADAKTIEKIVEEGYTLSDILNEITKEDLRYLRLRGGLLCRLWSAVSQYRRAQEAS
1250 1260 1270 1280 1290 1300
NP_001 ETKDKA
1310
1375 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:50:07 2016 done: Thu Nov 3 13:50:09 2016
Total Scan time: 15.160 Total Display time: 0.710
Function used was FASTA [36.3.4 Apr, 2011]