Result of FASTA (omim) for
pF1KB3699
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3699, 851 aa
1>>>pF1KB3699 851 - 851 aa - 851 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0146+/-0.00042; mu= 13.1398+/- 0.026
mean_var=122.7096+/-24.411, 0's: 0 Z-trim(114.9): 67 B-trim: 75 in 1/54
Lambda= 0.115780
statistics sampled from 24894 (24961) to 24894 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.293), width: 16
Scan time: 14.140
The best scores are: opt bits E(85289)
NP_005410 (OMIM: 600556,616636) signal transducer ( 851) 5722 967.8 0
XP_011536999 (OMIM: 600556,616636) PREDICTED: sign ( 859) 5696 963.4 0
NP_938146 (OMIM: 600556,616636) signal transducer ( 847) 5674 959.7 0
XP_011537000 (OMIM: 600556,616636) PREDICTED: sign ( 855) 5648 955.4 0
XP_016875393 (OMIM: 600556,616636) PREDICTED: sign ( 607) 3976 676.0 1.4e-193
XP_011537002 (OMIM: 600556,616636) PREDICTED: sign ( 615) 3950 671.7 2.9e-192
XP_011537001 (OMIM: 600556,616636) PREDICTED: sign ( 592) 3843 653.8 6.6e-187
XP_005269168 (OMIM: 600556,616636) PREDICTED: sign ( 464) 2957 505.7 1.9e-142
NP_644671 (OMIM: 600555,613796,614162,614892) sign ( 712) 1849 320.8 1.4e-86
XP_006712781 (OMIM: 600555,613796,614162,614892) P ( 750) 1849 320.8 1.5e-86
NP_009330 (OMIM: 600555,613796,614162,614892) sign ( 750) 1849 320.8 1.5e-86
XP_016860272 (OMIM: 600555,613796,614162,614892) P ( 752) 1849 320.8 1.5e-86
NP_003142 (OMIM: 600558,612253) signal transducer ( 748) 1767 307.1 2e-82
XP_011510007 (OMIM: 600558,612253) PREDICTED: sign ( 748) 1767 307.1 2e-82
XP_006712782 (OMIM: 600558,612253) PREDICTED: sign ( 748) 1767 307.1 2e-82
NP_001230764 (OMIM: 600558,612253) signal transduc ( 748) 1767 307.1 2e-82
NP_003141 (OMIM: 102582,147060,615952) signal tran ( 769) 1445 253.3 3.1e-66
XP_005257673 (OMIM: 102582,147060,615952) PREDICTE ( 769) 1445 253.3 3.1e-66
XP_016880464 (OMIM: 102582,147060,615952) PREDICTE ( 769) 1445 253.3 3.1e-66
XP_005257674 (OMIM: 102582,147060,615952) PREDICTE ( 770) 1445 253.3 3.1e-66
XP_011523447 (OMIM: 102582,147060,615952) PREDICTE ( 770) 1445 253.3 3.1e-66
NP_644805 (OMIM: 102582,147060,615952) signal tran ( 770) 1445 253.3 3.1e-66
XP_016880465 (OMIM: 102582,147060,615952) PREDICTE ( 721) 1443 253.0 3.7e-66
XP_016880462 (OMIM: 102582,147060,615952) PREDICTE ( 721) 1443 253.0 3.7e-66
XP_016880463 (OMIM: 102582,147060,615952) PREDICTE ( 721) 1443 253.0 3.7e-66
XP_016880461 (OMIM: 102582,147060,615952) PREDICTE ( 722) 1443 253.0 3.7e-66
XP_011523448 (OMIM: 102582,147060,615952) PREDICTE ( 722) 1443 253.0 3.7e-66
NP_998827 (OMIM: 102582,147060,615952) signal tran ( 722) 1443 253.0 3.7e-66
XP_016860273 (OMIM: 600558,612253) PREDICTED: sign ( 500) 1017 181.7 7.3e-45
XP_016880466 (OMIM: 245590,604260) PREDICTED: sign ( 693) 583 109.3 6.3e-23
NP_036580 (OMIM: 245590,604260) signal transducer ( 787) 583 109.3 7e-23
XP_005257681 (OMIM: 601511) PREDICTED: signal tran ( 761) 561 105.6 8.7e-22
NP_001275648 (OMIM: 601511) signal transducer and ( 764) 561 105.6 8.7e-22
NP_001275647 (OMIM: 601511) signal transducer and ( 794) 561 105.7 9e-22
NP_003143 (OMIM: 601511) signal transducer and act ( 794) 561 105.7 9e-22
NP_001171552 (OMIM: 601512) signal transducer and ( 737) 530 100.5 3.1e-20
NP_001171551 (OMIM: 601512) signal transducer and ( 737) 530 100.5 3.1e-20
NP_001171549 (OMIM: 601512) signal transducer and ( 847) 530 100.5 3.4e-20
NP_001171550 (OMIM: 601512) signal transducer and ( 847) 530 100.5 3.4e-20
NP_003144 (OMIM: 601512) signal transducer and act ( 847) 530 100.5 3.4e-20
XP_006719638 (OMIM: 601512) PREDICTED: signal tran ( 847) 530 100.5 3.4e-20
NP_001275649 (OMIM: 601511) signal transducer and ( 763) 345 69.6 6.3e-11
XP_011537010 (OMIM: 601512) PREDICTED: signal tran ( 755) 303 62.6 8.1e-09
XP_011537011 (OMIM: 601512) PREDICTED: signal tran ( 755) 303 62.6 8.1e-09
XP_011537005 (OMIM: 601512) PREDICTED: signal tran ( 865) 303 62.6 9.1e-09
XP_011537007 (OMIM: 601512) PREDICTED: signal tran ( 865) 303 62.6 9.1e-09
XP_011537008 (OMIM: 601512) PREDICTED: signal tran ( 865) 303 62.6 9.1e-09
XP_011537006 (OMIM: 601512) PREDICTED: signal tran ( 865) 303 62.6 9.1e-09
XP_011537009 (OMIM: 601512) PREDICTED: signal tran ( 865) 303 62.6 9.1e-09
XP_005257683 (OMIM: 245590,604260) PREDICTED: sign ( 497) 253 54.1 1.9e-06
>>NP_005410 (OMIM: 600556,616636) signal transducer and (851 aa)
initn: 5722 init1: 5722 opt: 5722 Z-score: 5170.5 bits: 967.8 E(85289): 0
Smith-Waterman score: 5722; 100.0% identity (100.0% similar) in 851 aa overlap (1-851:1-851)
10 20 30 40 50 60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
790 800 810 820 830 840
850
pF1KB3 YTDGPLMPSDF
:::::::::::
NP_005 YTDGPLMPSDF
850
>>XP_011536999 (OMIM: 600556,616636) PREDICTED: signal t (859 aa)
initn: 3223 init1: 3172 opt: 5696 Z-score: 5146.9 bits: 963.4 E(85289): 0
Smith-Waterman score: 5696; 99.1% identity (99.1% similar) in 859 aa overlap (1-851:1-859)
10 20 30 40 50 60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
430 440 450 460 470 480
490 500 510 520 530
pF1KB3 --------NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTLLPPLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB3 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB3 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB3 EENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLEL
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB3 KPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQ
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB3 TVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEV
790 800 810 820 830 840
840 850
pF1KB3 YVSRPSHFYTDGPLMPSDF
:::::::::::::::::::
XP_011 YVSRPSHFYTDGPLMPSDF
850
>>NP_938146 (OMIM: 600556,616636) signal transducer and (847 aa)
initn: 5025 init1: 5025 opt: 5674 Z-score: 5127.2 bits: 959.7 E(85289): 0
Smith-Waterman score: 5674; 99.5% identity (99.5% similar) in 851 aa overlap (1-851:1-847)
10 20 30 40 50 60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_938 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQ----DPTQLAEMIFNLLLEEKRILI
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB3 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB3 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB3 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB3 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
780 790 800 810 820 830
850
pF1KB3 YTDGPLMPSDF
:::::::::::
NP_938 YTDGPLMPSDF
840
>>XP_011537000 (OMIM: 600556,616636) PREDICTED: signal t (855 aa)
initn: 3236 init1: 2572 opt: 5648 Z-score: 5103.6 bits: 955.4 E(85289): 0
Smith-Waterman score: 5648; 98.6% identity (98.6% similar) in 859 aa overlap (1-851:1-855)
10 20 30 40 50 60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQ----DPTQLAEMIFNLLLEEKRILI
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
420 430 440 450 460 470
490 500 510 520 530
pF1KB3 --------NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTLLPPLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB3 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB3 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB3 EENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLEL
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB3 KPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQ
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB3 TVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEV
780 790 800 810 820 830
840 850
pF1KB3 YVSRPSHFYTDGPLMPSDF
:::::::::::::::::::
XP_011 YVSRPSHFYTDGPLMPSDF
840 850
>>XP_016875393 (OMIM: 600556,616636) PREDICTED: signal t (607 aa)
initn: 3976 init1: 3976 opt: 3976 Z-score: 3596.4 bits: 676.0 E(85289): 1.4e-193
Smith-Waterman score: 3976; 100.0% identity (100.0% similar) in 590 aa overlap (262-851:18-607)
240 250 260 270 280 290
pF1KB3 LPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDD
::::::::::::::::::::::::::::::
XP_016 MVRGTTPTLVLAMRCDLFTAGAKLLFHLRQLLKELKGLSCLVSYQDD
10 20 30 40
300 310 320 330 340 350
pF1KB3 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ
50 60 70 80 90 100
360 370 380 390 400 410
pF1KB3 EGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
110 120 130 140 150 160
420 430 440 450 460 470
pF1KB3 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
170 180 190 200 210 220
480 490 500 510 520 530
pF1KB3 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT
230 240 250 260 270 280
540 550 560 570 580 590
pF1KB3 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK
290 300 310 320 330 340
600 610 620 630 640 650
pF1KB3 KTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLL
350 360 370 380 390 400
660 670 680 690 700 710
pF1KB3 TEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLE
410 420 430 440 450 460
720 730 740 750 760 770
pF1KB3 LKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVS
470 480 490 500 510 520
780 790 800 810 820 830
pF1KB3 QTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDE
530 540 550 560 570 580
840 850
pF1KB3 VYVSRPSHFYTDGPLMPSDF
::::::::::::::::::::
XP_016 VYVSRPSHFYTDGPLMPSDF
590 600
>>XP_011537002 (OMIM: 600556,616636) PREDICTED: signal t (615 aa)
initn: 2572 init1: 2572 opt: 3950 Z-score: 3572.9 bits: 671.7 E(85289): 2.9e-192
Smith-Waterman score: 3950; 98.7% identity (98.7% similar) in 598 aa overlap (262-851:18-615)
240 250 260 270 280 290
pF1KB3 LPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDD
::::::::::::::::::::::::::::::
XP_011 MVRGTTPTLVLAMRCDLFTAGAKLLFHLRQLLKELKGLSCLVSYQDD
10 20 30 40
300 310 320 330 340 350
pF1KB3 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ
50 60 70 80 90 100
360 370 380 390 400 410
pF1KB3 EGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
110 120 130 140 150 160
420 430 440 450 460 470
pF1KB3 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
170 180 190 200 210 220
480 490 500 510 520
pF1KB3 FNLLSPNLQ--------NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNK
::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_011 FNLLSPNLQPTLLPPLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNK
230 240 250 260 270 280
530 540 550 560 570 580
pF1KB3 LFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSR
290 300 310 320 330 340
590 600 610 620 630 640
pF1KB3 SQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTE
350 360 370 380 390 400
650 660 670 680 690 700
pF1KB3 IIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQV
410 420 430 440 450 460
710 720 730 740 750 760
pF1KB3 DELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVI
470 480 490 500 510 520
770 780 790 800 810 820
pF1KB3 EPTLCMVSQTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPTLCMVSQTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLL
530 540 550 560 570 580
830 840 850
pF1KB3 AGQNTVDEVYVSRPSHFYTDGPLMPSDF
::::::::::::::::::::::::::::
XP_011 AGQNTVDEVYVSRPSHFYTDGPLMPSDF
590 600 610
>>XP_011537001 (OMIM: 600556,616636) PREDICTED: signal t (592 aa)
initn: 3867 init1: 3172 opt: 3843 Z-score: 3476.5 bits: 653.8 E(85289): 6.6e-187
Smith-Waterman score: 3843; 98.5% identity (98.6% similar) in 584 aa overlap (1-576:1-584)
10 20 30 40 50 60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
430 440 450 460 470 480
490 500 510 520 530
pF1KB3 --------NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTLLPPLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB3 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKK
:::::::::::::::::::::::::::::::::::::::::::.
XP_011 DPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGKKKKCCSSV
550 560 570 580 590
600 610 620 630 640 650
pF1KB3 TMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLT
>>XP_005269168 (OMIM: 600556,616636) PREDICTED: signal t (464 aa)
initn: 2957 init1: 2957 opt: 2957 Z-score: 2678.2 bits: 505.7 E(85289): 1.9e-142
Smith-Waterman score: 2957; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447)
10 20 30 40 50 60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
:::::::::::::::::::::::::::
XP_005 PLGVTEELHIISFTVKYTYQGLKQELKVSENGGQGERKQLWKKA
430 440 450 460
>>NP_644671 (OMIM: 600555,613796,614162,614892) signal t (712 aa)
initn: 1423 init1: 512 opt: 1849 Z-score: 1675.3 bits: 320.8 E(85289): 1.4e-86
Smith-Waterman score: 1851; 43.7% identity (71.6% similar) in 718 aa overlap (1-699:1-710)
10 20 30 40 50 60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
:.:: ::.::: : .:.::::. :. :..:::::: :.: :.:..:: .: : ::. :
NP_644 MSQWYELQQLDSKFLEQVHQLYDDSF-PMEIRQYLAQWLEKQDWEHAA--NDVSFATIRF
10 20 30 40 50
70 80 90 100 110
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL
.:.::. . .: : . ...:::::.:: :..: :..:: :.. .:.. : ::..::
NP_644 HDLLSQLDDQYSRFSLE-NNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKIL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 IQAQRAQLEQGEPVLETPVESQQHEIESRILDLR--AM-MEKLVKSISQLKDQQDVFCFR
.::: . :. . : . ..:.:..:.. ... .: .:. .::. .:.:. : :
NP_644 ENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 YKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIE--LLLPK
. . . . : .:: .:.. ::..::::. ::. .: : . :. .
NP_644 LQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLN-VTELTQNALINDE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLT
: ::: .::.::: .: . :.::..::: :. : ..:: ::.:. : .:. ::.:
NP_644 LVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPIT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 KGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGN
:. .. .. :.:.:.. .:::: ::::: :.:::.:::: .:::. ::::.::: :
NP_644 KNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 ESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
.: :.: .:.. . ..:::::::: .. :... :.. . .: .: .: : ::...
NP_644 YNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNA
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
:. .:.::: :::::: .:: .. :: .:.: .::::.:::..:: .:::.::
NP_644 GTR--TNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILW
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT
.:.: . .: .:: .:: : :. :. .::::::: . :::: :::.:: .::.: : .
NP_644 YNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNA-S
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB3 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK
: :. :. : :.. ..::: :...::::.. :: ::::: ::::.:. .:: :::
NP_644 PDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLK
540 550 560 570 580 590
600 610 620 630 640
pF1KB3 KTMSGTFLLRFSESS-EGGITCSWVEH-QDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQ
. ::::::::::: ::.:: .:::. :. . ...:.::::. :... . .:::.:.
NP_644 DQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYK
600 610 620 630 640 650
650 660 670 680 690 700
pF1KB3 LLTEENIPENPLRFLYPRIPRDEAFGCYYQ------EKVNLQERRK--YLKHRLIVVSNR
... ::::::::..::: : .:.::: ::. : ..:. . :.: .:: ::
NP_644 VMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEV
660 670 680 690 700 710
710 720 730 740 750 760
pF1KB3 QVDELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEP
>>XP_006712781 (OMIM: 600555,613796,614162,614892) PREDI (750 aa)
initn: 1423 init1: 512 opt: 1849 Z-score: 1675.0 bits: 320.8 E(85289): 1.5e-86
Smith-Waterman score: 1867; 43.4% identity (71.2% similar) in 737 aa overlap (1-717:1-729)
10 20 30 40 50 60
pF1KB3 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
:.:: ::.::: : .:.::::. :. :..:::::: :.: :.:..:: .: : ::. :
XP_006 MSQWYELQQLDSKFLEQVHQLYDDSF-PMEIRQYLAQWLEKQDWEHAA--NDVSFATIRF
10 20 30 40 50
70 80 90 100 110
pF1KB3 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL
.:.::. . .: : . ...:::::.:: :..: :..:: :.. .:.. : ::..::
XP_006 HDLLSQLDDQYSRFSLE-NNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKIL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 IQAQRAQLEQGEPVLETPVESQQHEIESRILDLR--AM-MEKLVKSISQLKDQQDVFCFR
.::: . :. . : . ..:.:..:.. ... .: .:. .::. .:.:. : :
XP_006 ENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 YKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIE--LLLPK
. . . . : .:: .:.. ::..::::. ::. .: : . :. .
XP_006 LQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLN-VTELTQNALINDE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLT
: ::: .::.::: .: . :.::..::: :. : ..:: ::.:. : .:. ::.:
XP_006 LVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPIT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 KGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGN
:. .. .. :.:.:.. .:::: ::::: :.:::.:::: .:::. ::::.::: :
XP_006 KNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 ESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG
.: :.: .:.. . ..:::::::: .. :... :.. . .: .: .: : ::...
XP_006 YNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNA
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW
:. .:.::: :::::: .:: .. :: .:.: .::::.:::..:: .:::.::
XP_006 GT--RTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILW
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB3 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT
.:.: . .: .:: .:: : :. :. .::::::: . :::: :::.:: .::.: : .
XP_006 YNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNA-S
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB3 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK
: :. :. : :.. ..::: :...::::.. :: ::::: ::::.:. .:: :::
XP_006 PDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLK
540 550 560 570 580 590
600 610 620 630 640
pF1KB3 KTMSGTFLLRFSESS-EGGITCSWVEH-QDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQ
. ::::::::::: ::.:: .:::. :. . ...:.::::. :... . .:::.:.
XP_006 DQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYK
600 610 620 630 640 650
650 660 670 680 690 700
pF1KB3 LLTEENIPENPLRFLYPRIPRDEAFGCYYQ------EKVNLQERRK--YLKHRLIVVSNR
... ::::::::..::: : .:.::: ::. : ..:. . :.: .:: ::.
XP_006 VMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEV
660 670 680 690 700 710
710 720 730 740 750 760
pF1KB3 QVDELQQPLELKP-EPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLE
. ..:: .: : ::
XP_006 HPSRLQTTDNLLPMSPEEFDEVSRIVGSVEFDSMMNTV
720 730 740 750
851 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:42:49 2016 done: Thu Nov 3 13:42:51 2016
Total Scan time: 14.140 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]