Result of FASTA (omim) for
pF1KB3509
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3509, 366 aa
1>>>pF1KB3509 366 - 366 aa - 366 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2835+/-0.000417; mu= 16.6845+/- 0.026
mean_var=69.3412+/-13.993, 0's: 0 Z-trim(110.7): 26 B-trim: 11 in 3/55
Lambda= 0.154020
statistics sampled from 19116 (19130) to 19116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.224), width: 16
Scan time: 7.740
The best scores are: opt bits E(85289)
NP_005521 (OMIM: 601149) isocitrate dehydrogenase ( 366) 2430 549.3 4.9e-156
XP_016877607 (OMIM: 601149) PREDICTED: isocitrate ( 316) 2097 475.3 8.2e-134
XP_016877608 (OMIM: 601149) PREDICTED: isocitrate ( 257) 1690 384.8 1.2e-106
XP_005254393 (OMIM: 601149) PREDICTED: isocitrate ( 257) 1690 384.8 1.2e-106
XP_016877609 (OMIM: 601149) PREDICTED: isocitrate ( 257) 1690 384.8 1.2e-106
NP_777280 (OMIM: 604526,612572) isocitrate dehydro ( 383) 964 223.6 5.8e-58
NP_008830 (OMIM: 604526,612572) isocitrate dehydro ( 385) 941 218.5 2e-56
NP_001317692 (OMIM: 604526,612572) isocitrate dehy ( 387) 941 218.5 2e-56
NP_004126 (OMIM: 300089) isocitrate dehydrogenase ( 393) 928 215.6 1.5e-55
NP_001245313 (OMIM: 604526,612572) isocitrate dehy ( 376) 893 207.8 3.2e-53
NP_777358 (OMIM: 300089) isocitrate dehydrogenase ( 380) 885 206.0 1.1e-52
>>NP_005521 (OMIM: 601149) isocitrate dehydrogenase [NAD (366 aa)
initn: 2430 init1: 2430 opt: 2430 Z-score: 2922.3 bits: 549.3 E(85289): 4.9e-156
Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR
310 320 330 340 350 360
pF1KB3 RVKDLD
::::::
NP_005 RVKDLD
>>XP_016877607 (OMIM: 601149) PREDICTED: isocitrate dehy (316 aa)
initn: 2097 init1: 2097 opt: 2097 Z-score: 2523.4 bits: 475.3 E(85289): 8.2e-134
Smith-Waterman score: 2097; 100.0% identity (100.0% similar) in 316 aa overlap (51-366:1-316)
30 40 50 60 70 80
pF1KB3 KQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMI
::::::::::::::::::::::::::::::
XP_016 MKIFDAAKAPIQWEERNVTAIQGPGGKWMI
10 20 30
90 100 110 120 130 140
pF1KB3 PSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDV
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB3 NIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHK
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB3 ANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB3 DLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGL
220 230 240 250 260 270
330 340 350 360
pF1KB3 FDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
280 290 300 310
>>XP_016877608 (OMIM: 601149) PREDICTED: isocitrate dehy (257 aa)
initn: 1690 init1: 1690 opt: 1690 Z-score: 2035.9 bits: 384.8 E(85289): 1.2e-106
Smith-Waterman score: 1690; 100.0% identity (100.0% similar) in 257 aa overlap (110-366:1-257)
80 90 100 110 120 130
pF1KB3 IPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTD
::::::::::::::::::::::::::::::
XP_016 MNLLLRKTFDLYANVRPCVSIEGYKTPYTD
10 20 30
140 150 160 170 180 190
pF1KB3 VNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVH
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB3 KANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDIL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB3 SDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMG
160 170 180 190 200 210
320 330 340 350 360
pF1KB3 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
220 230 240 250
>>XP_005254393 (OMIM: 601149) PREDICTED: isocitrate dehy (257 aa)
initn: 1690 init1: 1690 opt: 1690 Z-score: 2035.9 bits: 384.8 E(85289): 1.2e-106
Smith-Waterman score: 1690; 100.0% identity (100.0% similar) in 257 aa overlap (110-366:1-257)
80 90 100 110 120 130
pF1KB3 IPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTD
::::::::::::::::::::::::::::::
XP_005 MNLLLRKTFDLYANVRPCVSIEGYKTPYTD
10 20 30
140 150 160 170 180 190
pF1KB3 VNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVH
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB3 KANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDIL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB3 SDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMG
160 170 180 190 200 210
320 330 340 350 360
pF1KB3 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
220 230 240 250
>>XP_016877609 (OMIM: 601149) PREDICTED: isocitrate dehy (257 aa)
initn: 1690 init1: 1690 opt: 1690 Z-score: 2035.9 bits: 384.8 E(85289): 1.2e-106
Smith-Waterman score: 1690; 100.0% identity (100.0% similar) in 257 aa overlap (110-366:1-257)
80 90 100 110 120 130
pF1KB3 IPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTD
::::::::::::::::::::::::::::::
XP_016 MNLLLRKTFDLYANVRPCVSIEGYKTPYTD
10 20 30
140 150 160 170 180 190
pF1KB3 VNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVH
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB3 KANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDIL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB3 SDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMG
160 170 180 190 200 210
320 330 340 350 360
pF1KB3 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
220 230 240 250
>>NP_777280 (OMIM: 604526,612572) isocitrate dehydrogena (383 aa)
initn: 958 init1: 791 opt: 964 Z-score: 1161.5 bits: 223.6 E(85289): 5.8e-58
Smith-Waterman score: 964; 46.2% identity (75.7% similar) in 333 aa overlap (30-358:47-376)
10 20 30 40 50
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
: ::..::::.:::. :: ..: :: .
NP_777 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
NP_777 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
NP_777 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
NP_777 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
NP_777 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
. :...:::::.:::: ::::..: :.. : : .:: :: :.:.:: : : :::
NP_777 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYATCHDFT
320 330 340 350 360 370
360
pF1KB3 EEICRRVKDLD
: .
NP_777 EAVIAALPHP
380
>>NP_008830 (OMIM: 604526,612572) isocitrate dehydrogena (385 aa)
initn: 935 init1: 768 opt: 941 Z-score: 1133.9 bits: 218.5 E(85289): 2e-56
Smith-Waterman score: 941; 45.0% identity (75.4% similar) in 333 aa overlap (30-358:47-376)
10 20 30 40 50
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
: ::..::::.:::. :: ..: :: .
NP_008 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
NP_008 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
NP_008 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
NP_008 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
NP_008 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
. :...:::::.:::: ::::..: :.. : : .:: :: :.:.:: . .::
NP_008 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFI
320 330 340 350 360 370
360
pF1KB3 EEICRRVKDLD
. .
NP_008 KSVIGHLQTKGS
380
>>NP_001317692 (OMIM: 604526,612572) isocitrate dehydrog (387 aa)
initn: 935 init1: 768 opt: 941 Z-score: 1133.9 bits: 218.5 E(85289): 2e-56
Smith-Waterman score: 941; 45.0% identity (75.4% similar) in 333 aa overlap (30-358:47-376)
10 20 30 40 50
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
: ::..::::.:::. :: ..: :: .
NP_001 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
NP_001 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
NP_001 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
NP_001 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
NP_001 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
. :...:::::.:::: ::::..: :.. : : .:: :: :.:.:: . .::
NP_001 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFI
320 330 340 350 360 370
360
pF1KB3 EEICRRVKDLD
. .
NP_001 KSVIGHLQTKGSNL
380
>>NP_004126 (OMIM: 300089) isocitrate dehydrogenase [NAD (393 aa)
initn: 918 init1: 760 opt: 928 Z-score: 1118.1 bits: 215.6 E(85289): 1.5e-55
Smith-Waterman score: 928; 42.2% identity (72.8% similar) in 372 aa overlap (3-363:18-384)
10 20 30
pF1KB3 MAGPAWISKVSRLLGAFHNP-KQVTRGFT-------GGVQTVTLI
::: . . ..::: . : ... : :: .:::.:
NP_004 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKG
::::::::. : ..: : .:...:: .:.. .. .: .. .:...:::
NP_004 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSS----NADEEDIRNAIMAIRRNRVALKG
70 80 90 100 110
100 110 120 130 140 150
pF1KB3 PLKTP--IAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSG
..: . .: : : .:: ..:::::: : :. : : . :..:. .:::::::::.
NP_004 NIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB3 IEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKC
.:: : :::.:.:.::.. : ::::.::. :... :..::::::::::...:::::: :
NP_004 LEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCC
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB3 REVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPS
:::: .: :..: .:.. ...:. :.::::.:::::::.:....::::.:: :.. .
NP_004 REVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB3 GNIGANGVAIFESV-HGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFAT
.: : . :.::.. ..:. .::.:..::::: ::.. ::: :. : ..:. :. : .:.
NP_004 ANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLAS
300 310 320 330 340 350
340 350 360
pF1KB3 IKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
. . . : :.::.. :. ... :...
NP_004 MDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
360 370 380 390
>>NP_001245313 (OMIM: 604526,612572) isocitrate dehydrog (376 aa)
initn: 894 init1: 727 opt: 893 Z-score: 1076.4 bits: 207.8 E(85289): 3.2e-53
Smith-Waterman score: 893; 45.9% identity (76.1% similar) in 314 aa overlap (30-339:47-357)
10 20 30 40 50
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
: ::..::::.:::. :: ..: :: .
NP_001 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
NP_001 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
NP_001 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
NP_001 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
NP_001 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
. :...:::::.:::: ::::..: :.. : : .:: ::
NP_001 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKIPSAVPSFLLHPLPFS
320 330 340 350 360 370
360
pF1KB3 EEICRRVKDLD
NP_001 WAI
366 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:15:50 2016 done: Sat Nov 5 12:15:51 2016
Total Scan time: 7.740 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]