Result of FASTA (ccds) for
pF1KB3509
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3509, 366 aa
1>>>pF1KB3509 366 - 366 aa - 366 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5220+/-0.000963; mu= 15.4742+/- 0.058
mean_var=68.2174+/-13.574, 0's: 0 Z-trim(104.2): 21 B-trim: 5 in 2/50
Lambda= 0.155284
statistics sampled from 7779 (7788) to 7779 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.239), width: 16
Scan time: 2.590
The best scores are: opt bits E(32554)
CCDS10297.1 IDH3A gene_id:3419|Hs108|chr15 ( 366) 2430 553.5 1e-157
CCDS13031.1 IDH3B gene_id:3420|Hs108|chr20 ( 383) 964 225.1 7.7e-59
CCDS13032.1 IDH3B gene_id:3420|Hs108|chr20 ( 385) 941 220.0 2.8e-57
CCDS82594.1 IDH3B gene_id:3420|Hs108|chr20 ( 387) 941 220.0 2.8e-57
CCDS14730.1 IDH3G gene_id:3421|Hs108|chrX ( 393) 928 217.1 2.1e-56
CCDS74696.1 IDH3B gene_id:3420|Hs108|chr20 ( 376) 893 209.2 4.7e-54
CCDS44019.1 IDH3G gene_id:3421|Hs108|chrX ( 380) 885 207.4 1.6e-53
>>CCDS10297.1 IDH3A gene_id:3419|Hs108|chr15 (366 aa)
initn: 2430 init1: 2430 opt: 2430 Z-score: 2945.1 bits: 553.5 E(32554): 1e-157
Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR
310 320 330 340 350 360
pF1KB3 RVKDLD
::::::
CCDS10 RVKDLD
>>CCDS13031.1 IDH3B gene_id:3420|Hs108|chr20 (383 aa)
initn: 958 init1: 791 opt: 964 Z-score: 1169.8 bits: 225.1 E(32554): 7.7e-59
Smith-Waterman score: 964; 46.2% identity (75.7% similar) in 333 aa overlap (30-358:47-376)
10 20 30 40 50
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
: ::..::::.:::. :: ..: :: .
CCDS13 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
CCDS13 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
CCDS13 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
CCDS13 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
CCDS13 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
. :...:::::.:::: ::::..: :.. : : .:: :: :.:.:: : : :::
CCDS13 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYATCHDFT
320 330 340 350 360 370
360
pF1KB3 EEICRRVKDLD
: .
CCDS13 EAVIAALPHP
380
>>CCDS13032.1 IDH3B gene_id:3420|Hs108|chr20 (385 aa)
initn: 935 init1: 768 opt: 941 Z-score: 1141.9 bits: 220.0 E(32554): 2.8e-57
Smith-Waterman score: 941; 45.0% identity (75.4% similar) in 333 aa overlap (30-358:47-376)
10 20 30 40 50
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
: ::..::::.:::. :: ..: :: .
CCDS13 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
CCDS13 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
CCDS13 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
CCDS13 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
CCDS13 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
. :...:::::.:::: ::::..: :.. : : .:: :: :.:.:: . .::
CCDS13 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFI
320 330 340 350 360 370
360
pF1KB3 EEICRRVKDLD
. .
CCDS13 KSVIGHLQTKGS
380
>>CCDS82594.1 IDH3B gene_id:3420|Hs108|chr20 (387 aa)
initn: 935 init1: 768 opt: 941 Z-score: 1141.9 bits: 220.0 E(32554): 2.8e-57
Smith-Waterman score: 941; 45.0% identity (75.4% similar) in 333 aa overlap (30-358:47-376)
10 20 30 40 50
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
: ::..::::.:::. :: ..: :: .
CCDS82 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
CCDS82 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
CCDS82 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
CCDS82 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
CCDS82 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
. :...:::::.:::: ::::..: :.. : : .:: :: :.:.:: . .::
CCDS82 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFI
320 330 340 350 360 370
360
pF1KB3 EEICRRVKDLD
. .
CCDS82 KSVIGHLQTKGSNL
380
>>CCDS14730.1 IDH3G gene_id:3421|Hs108|chrX (393 aa)
initn: 918 init1: 760 opt: 928 Z-score: 1126.0 bits: 217.1 E(32554): 2.1e-56
Smith-Waterman score: 928; 42.2% identity (72.8% similar) in 372 aa overlap (3-363:18-384)
10 20 30
pF1KB3 MAGPAWISKVSRLLGAFHNP-KQVTRGFT-------GGVQTVTLI
::: . . ..::: . : ... : :: .:::.:
CCDS14 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKG
::::::::. : ..: : .:...:: .:.. .. .: .. .:...:::
CCDS14 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSS----NADEEDIRNAIMAIRRNRVALKG
70 80 90 100 110
100 110 120 130 140 150
pF1KB3 PLKTP--IAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSG
..: . .: : : .:: ..:::::: : :. : : . :..:. .:::::::::.
CCDS14 NIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB3 IEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKC
.:: : :::.:.:.::.. : ::::.::. :... :..::::::::::...:::::: :
CCDS14 LEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCC
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB3 REVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPS
:::: .: :..: .:.. ...:. :.::::.:::::::.:....::::.:: :.. .
CCDS14 REVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB3 GNIGANGVAIFESV-HGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFAT
.: : . :.::.. ..:. .::.:..::::: ::.. ::: :. : ..:. :. : .:.
CCDS14 ANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLAS
300 310 320 330 340 350
340 350 360
pF1KB3 IKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
. . . : :.::.. :. ... :...
CCDS14 MDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA
360 370 380 390
>>CCDS74696.1 IDH3B gene_id:3420|Hs108|chr20 (376 aa)
initn: 894 init1: 727 opt: 893 Z-score: 1084.0 bits: 209.2 E(32554): 4.7e-54
Smith-Waterman score: 893; 45.9% identity (76.1% similar) in 314 aa overlap (30-339:47-357)
10 20 30 40 50
pF1KB3 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
: ::..::::.:::. :: ..: :: .
CCDS74 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
CCDS74 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
CCDS74 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
CCDS74 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
CCDS74 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
260 270 280 290 300 310
300 310 320 330 340 350
pF1KB3 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
. :...:::::.:::: ::::..: :.. : : .:: ::
CCDS74 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKIPSAVPSFLLHPLPFS
320 330 340 350 360 370
360
pF1KB3 EEICRRVKDLD
CCDS74 WAI
>>CCDS44019.1 IDH3G gene_id:3421|Hs108|chrX (380 aa)
initn: 875 init1: 717 opt: 885 Z-score: 1074.2 bits: 207.4 E(32554): 1.6e-53
Smith-Waterman score: 885; 43.6% identity (73.4% similar) in 346 aa overlap (3-337:18-358)
10 20 30
pF1KB3 MAGPAWISKVSRLLGAFHNP-KQVTRGFT-------GGVQTVTLI
::: . . ..::: . : ... : :: .:::.:
CCDS44 MALKVATVAGSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKG
::::::::. : ..: : .:...:: .:.. .. .: .. .:...:::
CCDS44 PGDGIGPELMLHVKSVFRHACVPVDFEEVHVSS----NADEEDIRNAIMAIRRNRVALKG
70 80 90 100 110
100 110 120 130 140 150
pF1KB3 PLKTP--IAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSG
..: . .: : : .:: ..:::::: : :. : : . :..:. .:::::::::.
CCDS44 NIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB3 IEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKC
.:: : :::.:.:.::.. : ::::.::. :... :..::::::::::...:::::: :
CCDS44 LEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCC
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB3 REVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPS
:::: .: :..: .:.. ...:. :.::::.:::::::.:....::::.:: :.. .
CCDS44 REVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB3 GNIGANGVAIFESV-HGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFAT
.: : . :.::.. ..:. .::.:..::::: ::.. ::: :. : ..:. :. : .:.
CCDS44 ANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLAS
300 310 320 330 340 350
340 350 360
pF1KB3 IKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
. .
CCDS44 MDNENVRFPSHPTLLPRPVSPCSLL
360 370 380
366 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:15:49 2016 done: Sat Nov 5 12:15:49 2016
Total Scan time: 2.590 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]