Result of FASTA (omim) for
pF1KB3506
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3506, 269 aa
1>>>pF1KB3506 269 - 269 aa - 269 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7942+/-0.000444; mu= 17.0638+/- 0.027
mean_var=55.5643+/-11.359, 0's: 0 Z-trim(108.8): 64 B-trim: 28 in 1/48
Lambda= 0.172058
statistics sampled from 16882 (16935) to 16882 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.552), E-opt: 0.2 (0.199), width: 16
Scan time: 6.290
The best scores are: opt bits E(85289)
NP_932766 (OMIM: 107776,110450) aquaporin-1 isofor ( 269) 1731 438.1 8.1e-123
NP_001316801 (OMIM: 107776,110450) aquaporin-1 iso ( 323) 1692 428.5 7.8e-120
NP_036196 (OMIM: 154050,615274) lens fiber major i ( 263) 777 201.3 1.5e-51
NP_000477 (OMIM: 107777,125800) aquaporin-2 [Homo ( 271) 768 199.1 7.4e-51
NP_001642 (OMIM: 600442) aquaporin-5 [Homo sapiens ( 265) 751 194.8 1.4e-49
NP_004019 (OMIM: 600308) aquaporin-4 isoform M23 [ ( 301) 722 187.7 2.2e-47
XP_011524244 (OMIM: 600308) PREDICTED: aquaporin-4 ( 316) 722 187.7 2.3e-47
NP_001641 (OMIM: 600308) aquaporin-4 isoform M1 [H ( 323) 722 187.7 2.4e-47
NP_001304313 (OMIM: 600308) aquaporin-4 isoform M1 ( 352) 722 187.7 2.5e-47
NP_001643 (OMIM: 601383) aquaporin-6 [Homo sapiens ( 282) 634 165.8 7.9e-41
XP_005268895 (OMIM: 600442) PREDICTED: aquaporin-5 ( 222) 625 163.5 3.1e-40
NP_001304316 (OMIM: 600308) aquaporin-4 isoform de ( 296) 508 134.5 2.1e-31
XP_011536656 (OMIM: 154050,615274) PREDICTED: lens ( 168) 456 121.5 1e-27
XP_016874795 (OMIM: 154050,615274) PREDICTED: lens ( 144) 443 118.2 8.5e-27
NP_001160 (OMIM: 603750) aquaporin-8 [Homo sapiens ( 261) 346 94.3 2.5e-19
XP_011544124 (OMIM: 603750) PREDICTED: aquaporin-8 ( 262) 346 94.3 2.5e-19
XP_011544125 (OMIM: 603750) PREDICTED: aquaporin-8 ( 148) 187 54.7 1.2e-07
NP_001307564 (OMIM: 602914) aquaporin-9 isoform 2 ( 193) 163 48.8 9.1e-06
NP_066190 (OMIM: 602914) aquaporin-9 isoform 1 [Ho ( 295) 163 48.9 1.3e-05
NP_001305073 (OMIM: 600170,607457) aquaporin-3 iso ( 237) 158 47.6 2.5e-05
NP_004916 (OMIM: 600170,607457) aquaporin-3 isofor ( 292) 158 47.7 3e-05
NP_001305086 (OMIM: 602974,614411) aquaporin-7 iso ( 256) 140 43.2 0.0006
NP_001305087 (OMIM: 602974,614411) aquaporin-7 iso ( 257) 140 43.2 0.0006
XP_016870189 (OMIM: 602974,614411) PREDICTED: aqua ( 341) 140 43.2 0.00076
NP_001161 (OMIM: 602974,614411) aquaporin-7 isofor ( 342) 140 43.2 0.00076
XP_011516168 (OMIM: 602974,614411) PREDICTED: aqua ( 342) 140 43.2 0.00076
XP_005251510 (OMIM: 602974,614411) PREDICTED: aqua ( 342) 140 43.2 0.00076
NP_001307565 (OMIM: 602914) aquaporin-9 isoform 3 ( 230) 132 41.1 0.0022
NP_945349 (OMIM: 609789) aquaporin-12A precursor [ ( 295) 132 41.2 0.0027
XP_011508406 (OMIM: 606578) PREDICTED: aquaporin-1 ( 302) 130 40.7 0.0038
NP_536354 (OMIM: 606578) aquaporin-10 [Homo sapien ( 301) 129 40.5 0.0046
>>NP_932766 (OMIM: 107776,110450) aquaporin-1 isoform 1 (269 aa)
initn: 1731 init1: 1731 opt: 1731 Z-score: 2325.9 bits: 438.1 E(85289): 8.1e-123
Smith-Waterman score: 1731; 100.0% identity (100.0% similar) in 269 aa overlap (1-269:1-269)
10 20 30 40 50 60
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_932 LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
190 200 210 220 230 240
250 260
pF1KB3 RVKVWTSGQVEEYDLDADDINSRVEMKPK
:::::::::::::::::::::::::::::
NP_932 RVKVWTSGQVEEYDLDADDINSRVEMKPK
250 260
>>NP_001316801 (OMIM: 107776,110450) aquaporin-1 isoform (323 aa)
initn: 1691 init1: 1691 opt: 1692 Z-score: 2272.4 bits: 428.5 E(85289): 7.8e-120
Smith-Waterman score: 1692; 98.1% identity (98.5% similar) in 269 aa overlap (1-269:1-269)
10 20 30 40 50 60
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
190 200 210 220 230 240
250 260
pF1KB3 RVKVWTSGQVEEYDLDADDINSRVEMKPK
::::::::::::::::::::::: . :
NP_001 RVKVWTSGQVEEYDLDADDINSRSFLGTKIYQFTHSLEVVEEVKERDPPASRPSEHDGRC
250 260 270 280 290 300
>>NP_036196 (OMIM: 154050,615274) lens fiber major intri (263 aa)
initn: 793 init1: 695 opt: 777 Z-score: 1046.2 bits: 201.3 E(85289): 1.5e-51
Smith-Waterman score: 777; 48.1% identity (81.3% similar) in 241 aa overlap (4-244:3-236)
10 20 30 40 50 60
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
:... ::::. :::.:: ..::...::.: .. : .. ..:..::::..
NP_036 MWELRSASFWRAIFAEFFATLFYVFFGLGSSL--RWAPGPLHV-----LQVAMAFGLAL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
:::.::::::::::.:::::...:.. :.:..::. :. :: .::....:.: ..: .
NP_036 ATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
..:. : : .:. ::. .::. :::.:::..:: :.:: ::. ::.:.:.::::
NP_036 RGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
:... ::: :.::::::. :..: ::.:::..::::.:::.:. :.:::.: :: .....
NP_036 LFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISE
180 190 200 210 220 230
250 260
pF1KB3 RVKVWTSGQVEEYDLDADDINSRVEMKPK
:..:
NP_036 RLSVLKGAKPDVSNGQPEVTGEPVELNTQAL
240 250 260
>>NP_000477 (OMIM: 107777,125800) aquaporin-2 [Homo sapi (271 aa)
initn: 787 init1: 664 opt: 768 Z-score: 1034.0 bits: 199.1 E(85289): 7.4e-51
Smith-Waterman score: 768; 45.0% identity (79.6% similar) in 260 aa overlap (4-263:3-254)
10 20 30 40 50 60
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
:... : ::: :::::: ::::...:::: ..: :. . .....::::.:
NP_000 MWELRSIAFSRAVFAEFLATLLFVFFGLGSAL--NWP-----QALPSVLQIAMAFGLGI
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
.::.:..:::::::.:::::.. :..:..:..:: .:. :: .::....:.: :: .
NP_000 GTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
..:. : :......::.. .:.. :::::::..:.::.:: . :. :.::.::::::
NP_000 RGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 LLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTD
::.: ::::..:::::.. ::.: .:..::.::.::..:. :. :.:...: : ...:..
NP_000 LLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSE
180 190 200 210 220 230
250 260
pF1KB3 RVKVWTSGQVEEYDLDADDINSRVEMKPK
:. : .: . : . .. :
NP_000 RLAV-LKGLEPDTDWEEREVRRRQSVELHSPQSLPRGTKA
240 250 260 270
>>NP_001642 (OMIM: 600442) aquaporin-5 [Homo sapiens] (265 aa)
initn: 742 init1: 524 opt: 751 Z-score: 1011.3 bits: 194.8 E(85289): 1.4e-49
Smith-Waterman score: 751; 46.6% identity (77.2% similar) in 268 aa overlap (1-267:1-257)
10 20 30 40 50 60
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSI
: .: . : .:: :::::: .:::...:::: :.: .:. ....:::::.:
NP_001 MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSAL--KWP-----SALPTILQIALAFGLAI
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 ATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLT
.::::..: .::.:.:::.::.::.. :::..::..:. :: ::::....:: :.. .
NP_001 GTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 GNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGH
..:. : : .....::.. .:.: :.::.::..:.:: :: . :: :.:::::.:::
NP_001 RGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGH
120 130 140 150 160 170
190 200 210 220 230
pF1KB3 LLAIDYTGCGINPARSFGSAVITHNFS-NHWIFWVGPFIGGALAVLIYDFILAPRSSDLT
:..: .:::..::::::: ::. . :: ::.:::::..:..::...: ..: : : .:.
NP_001 LVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLS
180 190 200 210 220 230
240 250 260
pF1KB3 DRVKVWTSGQVEEYDLDADDINSRVEMKPK
.:: . .: :. : : ..: : :
NP_001 ERVAI-IKGT---YEPDEDWEEQREERKKTMELTTR
240 250 260
>>NP_004019 (OMIM: 600308) aquaporin-4 isoform M23 [Homo (301 aa)
initn: 698 init1: 608 opt: 722 Z-score: 971.6 bits: 187.7 E(85289): 2.2e-47
Smith-Waterman score: 722; 44.8% identity (75.7% similar) in 259 aa overlap (10-265:12-266)
10 20 30 40 50
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGL
::.::.::::: .::..:.::.... :... : : .:: :::
NP_004 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG---GTEKPLPVDMVLISLCFGL
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 SIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSS
::::..: :::::.:.:::::.... . .::: ....:: :::.:::....:: .:
NP_004 SIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 LTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVAL
. ..:: . . ....:.:: .:.: :.:::. ..:. : .: :. :: ::::.:::.
NP_004 SVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 GHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDL
:::.::.::: ..::::::: ::: :. ::::.::::.::..:: .:.... : . ..
NP_004 GHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCP-DVEF
180 190 200 210 220 230
240 250 260
pF1KB3 TDRVKVWTSGQVEEYD---LDADDINSRVEMKPK
: : : ... ....: :.::
NP_004 KRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEEKKGKDQSGE
240 250 260 270 280 290
>>XP_011524244 (OMIM: 600308) PREDICTED: aquaporin-4 iso (316 aa)
initn: 698 init1: 608 opt: 722 Z-score: 971.3 bits: 187.7 E(85289): 2.3e-47
Smith-Waterman score: 722; 44.8% identity (75.7% similar) in 259 aa overlap (10-265:27-281)
10 20 30 40
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQ
::.::.::::: .::..:.::.... :...
XP_011 MFEIKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG---GTEK
10 20 30 40 50
50 60 70 80 90 100
pF1KB3 TAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCV
: : .:: :::::::..: :::::.:.:::::.... . .::: ....:: :::.
XP_011 PLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB3 GAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRD
:::....:: .: . ..:: . . ....:.:: .:.: :.:::. ..:. : .: :
XP_011 GAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB3 LGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALA
. :: ::::.:::.:::.::.::: ..::::::: ::: :. ::::.::::.::..::
XP_011 VTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLA
180 190 200 210 220 230
230 240 250 260
pF1KB3 VLIYDFILAPRSSDLTDRVKVWTSGQVEEYD---LDADDINSRVEMKPK
.:.... : . .. : : : ... ....: :.::
XP_011 GGLYEYVFCP-DVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVID
240 250 260 270 280 290
XP_011 VDRGEEKKGKDQSGEVLSSV
300 310
>>NP_001641 (OMIM: 600308) aquaporin-4 isoform M1 [Homo (323 aa)
initn: 698 init1: 608 opt: 722 Z-score: 971.1 bits: 187.7 E(85289): 2.4e-47
Smith-Waterman score: 722; 44.8% identity (75.7% similar) in 259 aa overlap (10-265:34-288)
10 20 30
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPV
::.::.::::: .::..:.::....
NP_001 RPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG---
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 GNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYII
:... : : .:: :::::::..: :::::.:.:::::.... . .::: ....::
NP_001 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 AQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDR
:::.:::....:: .: . ..:: . . ....:.:: .:.: :.:::. ..:. :
NP_001 AQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 RRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIG
.: :. :: ::::.:::.:::.::.::: ..::::::: ::: :. ::::.::::.::
NP_001 KRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG
190 200 210 220 230 240
220 230 240 250 260
pF1KB3 GALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYD---LDADDINSRVEMKPK
..:: .:.... : . .. : : : ... ....: :.::
NP_001 AVLAGGLYEYVFCP-DVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVV
250 260 270 280 290
NP_001 HVIDVDRGEEKKGKDQSGEVLSSV
300 310 320
>>NP_001304313 (OMIM: 600308) aquaporin-4 isoform M1x [H (352 aa)
initn: 698 init1: 608 opt: 722 Z-score: 970.6 bits: 187.7 E(85289): 2.5e-47
Smith-Waterman score: 722; 44.8% identity (75.7% similar) in 259 aa overlap (10-265:34-288)
10 20 30
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPV
::.::.::::: .::..:.::....
NP_001 RPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG---
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 GNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYII
:... : : .:: :::::::..: :::::.:.:::::.... . .::: ....::
NP_001 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 AQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDR
:::.:::....:: .: . ..:: . . ....:.:: .:.: :.:::. ..:. :
NP_001 AQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 RRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIG
.: :. :: ::::.:::.:::.::.::: ..::::::: ::: :. ::::.::::.::
NP_001 KRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG
190 200 210 220 230 240
220 230 240 250 260
pF1KB3 GALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYD---LDADDINSRVEMKPK
..:: .:.... : . .. : : : ... ....: :.::
NP_001 AVLAGGLYEYVFCP-DVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVV
250 260 270 280 290
NP_001 HVIDVDRGEEKKGKDQSGEVLSSVXLEDRTESRQDSLELSSDFLPPIKETDLL
300 310 320 330 340 350
>>NP_001643 (OMIM: 601383) aquaporin-6 [Homo sapiens] (282 aa)
initn: 697 init1: 326 opt: 634 Z-score: 854.0 bits: 165.8 E(85289): 7.9e-41
Smith-Waterman score: 686; 46.2% identity (76.2% similar) in 240 aa overlap (12-251:25-254)
10 20 30 40
pF1KB3 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQ
::. :::::: :.::...::.. ..: ::.
NP_001 MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVM--RWP-----TALP
10 20 30 40 50
50 60 70 80 90 100
pF1KB3 DNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIV
. ......:.: : .: . . :::: ::::::..:.. .::. ::. :. :: ::: :
NP_001 SVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB3 ATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGS
..:.: :. . ..:: : . ..:..::....:.. ::::::::.:.:: :. .::
NP_001 GAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQT--SGS
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB3 APLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIY
::.:::::::..: .:::..::::::: :.: .:. ::.:::::..:. :: :::
NP_001 PATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIY
180 190 200 210 220 230
230 240 250 260
pF1KB3 DFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK
.:.: : .. :..:. . : : ::
NP_001 NFVLFPDTKTLAQRLAILT-GTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
240 250 260 270 280
269 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:33:57 2016 done: Fri Nov 4 02:33:58 2016
Total Scan time: 6.290 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]