Result of FASTA (omim) for
pF1KB3489
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3489, 332 aa
1>>>pF1KB3489 332 - 332 aa - 332 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0807+/-0.00038; mu= 17.4716+/- 0.024
mean_var=65.6698+/-12.937, 0's: 0 Z-trim(112.2): 144 B-trim: 0 in 0/53
Lambda= 0.158267
statistics sampled from 20838 (20988) to 20838 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.246), width: 16
Scan time: 7.720
The best scores are: opt bits E(85289)
NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine ( 332) 2116 492.0 7.2e-139
XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 298) 1645 384.5 1.6e-106
XP_016881179 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 255) 1632 381.4 1.1e-105
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310) 310 79.6 9.3e-15
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325) 310 79.7 9.6e-15
NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325) 310 79.7 9.6e-15
XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334) 310 79.7 9.9e-15
XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 310 79.7 1.1e-14
XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 310 79.7 1.1e-14
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289) 296 76.4 8e-14
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339) 296 76.5 9.1e-14
NP_001207422 (OMIM: 616161) dehydrogenase/reductas ( 312) 295 76.2 1e-13
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404) 296 76.5 1.1e-13
NP_001099041 (OMIM: 616161) dehydrogenase/reductas ( 311) 294 76.0 1.2e-13
NP_056540 (OMIM: 608575) retinol dehydrogenase 8 [ ( 331) 292 75.6 1.7e-13
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309) 277 72.1 1.7e-12
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318) 277 72.1 1.8e-12
NP_005516 (OMIM: 600713,614662) corticosteroid 11- ( 292) 263 68.9 1.5e-11
NP_001193670 (OMIM: 600713,614662) corticosteroid ( 292) 263 68.9 1.5e-11
NP_861420 (OMIM: 600713,614662) corticosteroid 11- ( 292) 263 68.9 1.5e-11
NP_000405 (OMIM: 233400,261515,601860) peroxisomal ( 736) 264 69.4 2.7e-11
NP_057110 (OMIM: 607849,616108) retinol dehydrogen ( 318) 246 65.0 2.4e-10
NP_057226 (OMIM: 609574) very-long-chain 3-oxoacyl ( 312) 240 63.7 6e-10
NP_004744 (OMIM: 612830) short-chain dehydrogenase ( 302) 232 61.8 2.1e-09
NP_000404 (OMIM: 109684) estradiol 17-beta-dehydro ( 328) 232 61.9 2.2e-09
XP_016873370 (OMIM: 609574) PREDICTED: very-long-c ( 280) 231 61.6 2.3e-09
XP_011523032 (OMIM: 109684) PREDICTED: estradiol 1 ( 383) 232 61.9 2.5e-09
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278) 229 61.1 3.1e-09
XP_016862499 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324) 229 61.2 3.6e-09
XP_016862498 (OMIM: 603063) PREDICTED: D-beta-hydr ( 324) 229 61.2 3.6e-09
XP_016862500 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 229 61.2 3.6e-09
XP_016862497 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 229 61.2 3.6e-09
XP_016862501 (OMIM: 603063) PREDICTED: D-beta-hydr ( 330) 229 61.2 3.6e-09
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 228 60.9 3.7e-09
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 228 60.9 3.7e-09
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280) 228 60.9 3.7e-09
NP_976059 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 229 61.2 3.7e-09
XP_005269409 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343) 229 61.2 3.7e-09
XP_016862496 (OMIM: 603063) PREDICTED: D-beta-hydr ( 343) 229 61.2 3.7e-09
NP_976060 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 229 61.2 3.7e-09
NP_004042 (OMIM: 603063) D-beta-hydroxybutyrate de ( 343) 229 61.2 3.7e-09
XP_011511369 (OMIM: 603063) PREDICTED: D-beta-hydr ( 347) 229 61.2 3.8e-09
NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300) 228 60.9 3.9e-09
NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300) 226 60.5 5.4e-09
NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl ( 303) 226 60.5 5.4e-09
NP_689656 (OMIM: 608830,612712) retinol dehydrogen ( 316) 224 60.0 7.7e-09
NP_077284 (OMIM: 616159) dehydrogenase/reductase S ( 260) 222 59.5 9e-09
NP_001317148 (OMIM: 109684) estradiol 17-beta-dehy ( 329) 222 59.6 1.1e-08
XP_011523031 (OMIM: 109684) PREDICTED: estradiol 1 ( 384) 222 59.6 1.2e-08
XP_005257349 (OMIM: 109684) PREDICTED: estradiol 1 ( 359) 216 58.2 3e-08
>>NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine redu (332 aa)
initn: 2116 init1: 2116 opt: 2116 Z-score: 2614.1 bits: 492.0 E(85289): 7.2e-139
Smith-Waterman score: 2116; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332)
10 20 30 40 50 60
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
250 260 270 280 290 300
310 320 330
pF1KB3 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
::::::::::::::::::::::::::::::::
NP_002 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
310 320 330
>>XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihydrosp (298 aa)
initn: 1880 init1: 1645 opt: 1645 Z-score: 2033.6 bits: 384.5 E(85289): 1.6e-106
Smith-Waterman score: 1816; 89.8% identity (89.8% similar) in 332 aa overlap (1-332:1-298)
10 20 30 40 50 60
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLF
::::::::::::::::::: :::::::
XP_005 TTSVCKPEQVAKQIVKDAI----------------------------------VVTMGLF
250 260
310 320 330
pF1KB3 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
::::::::::::::::::::::::::::::::
XP_005 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
270 280 290
>>XP_016881179 (OMIM: 136440) PREDICTED: 3-ketodihydrosp (255 aa)
initn: 1632 init1: 1632 opt: 1632 Z-score: 2018.5 bits: 381.4 E(85289): 1.1e-105
Smith-Waterman score: 1632; 100.0% identity (100.0% similar) in 255 aa overlap (78-332:1-255)
50 60 70 80 90 100
pF1KB3 IAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQ
::::::::::::::::::::::::::::::
XP_016 MHSINDKQVVLCISVDVSQDYNQVENVIKQ
10 20 30
110 120 130 140 150 160
pF1KB3 AQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGR
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB3 IVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB3 NRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSI
160 170 180 190 200 210
290 300 310 320 330
pF1KB3 TEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA
220 230 240 250
>>NP_001317088 (OMIM: 616160) dehydrogenase/reductase SD (310 aa)
initn: 308 init1: 234 opt: 310 Z-score: 385.9 bits: 79.6 E(85289): 9.3e-15
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:35-222)
10 20 30 40 50
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
: .: ::.::..::.:: : : :: .
NP_001 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
.: .:: : . .:. . :. .. :.. : . . . . . .: ::.
NP_001 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
::: ::.. : . : :.. .:.: ::.: : ..:.. .: .:: :.:: .:: :.
NP_001 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
... .::.::: : ... . :. :.. :.. .:: :
NP_001 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
NP_001 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
250 260 270 280 290 300
>>XP_016879915 (OMIM: 616160) PREDICTED: dehydrogenase/r (325 aa)
initn: 308 init1: 234 opt: 310 Z-score: 385.7 bits: 79.7 E(85289): 9.6e-15
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:50-237)
10 20 30 40 50
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
: .: ::.::..::.:: : : :: .
XP_016 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
.: .:: : . .:. . :. .. :.. : . . . . . .: ::.
XP_016 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
::: ::.. : . : :.. .:.: ::.: : ..:.. .: .:: :.:: .:: :.
XP_016 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
... .::.::: : ... . :. :.. :.. .:: :
XP_016 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
XP_016 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
260 270 280 290 300 310
>>NP_056325 (OMIM: 616160) dehydrogenase/reductase SDR f (325 aa)
initn: 308 init1: 234 opt: 310 Z-score: 385.7 bits: 79.7 E(85289): 9.6e-15
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:50-237)
10 20 30 40 50
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
: .: ::.::..::.:: : : :: .
NP_056 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
.: .:: : . .:. . :. .. :.. : . . . . . .: ::.
NP_056 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
::: ::.. : . : :.. .:.: ::.: : ..:.. .: .:: :.:: .:: :.
NP_056 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
140 150 160 170 180 190
180 190 200 210 220 230
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
... .::.::: : ... . :. :.. :.. .:: :
NP_056 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
200 210 220 230 240 250
240 250 260 270 280 290
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
NP_056 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
260 270 280 290 300 310
>>XP_011522088 (OMIM: 616160) PREDICTED: dehydrogenase/r (334 aa)
initn: 302 init1: 228 opt: 310 Z-score: 385.5 bits: 79.7 E(85289): 9.9e-15
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:97-284)
10 20 30 40 50
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
: .: ::.::..::.:: : : :: .
XP_011 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
.: .:: : . .:. . :. .. :.. : . . . . . .: ::.
XP_011 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
::: ::.. : . : :.. .:.: ::.: : ..:.. .: .:: :.:: .:: :.
XP_011 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
... .::.::: : ... . :. :.. :.. .:: :
XP_011 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSSYGH
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
XP_011 HHSPGPKPCGGGPGCSCCCGEEEERCDPG
310 320 330
>>XP_016879914 (OMIM: 616160) PREDICTED: dehydrogenase/r (372 aa)
initn: 308 init1: 234 opt: 310 Z-score: 384.8 bits: 79.7 E(85289): 1.1e-14
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:97-284)
10 20 30 40 50
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
: .: ::.::..::.:: : : :: .
XP_016 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
.: .:: : . .:. . :. .. :.. : . . . . . .: ::.
XP_016 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
::: ::.. : . : :.. .:.: ::.: : ..:.. .: .:: :.:: .:: :.
XP_016 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
... .::.::: : ... . :. :.. :.. .:: :
XP_016 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
XP_016 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
310 320 330 340 350 360
>>XP_005256652 (OMIM: 616160) PREDICTED: dehydrogenase/r (372 aa)
initn: 308 init1: 234 opt: 310 Z-score: 384.8 bits: 79.7 E(85289): 1.1e-14
Smith-Waterman score: 310; 32.3% identity (61.9% similar) in 189 aa overlap (30-216:97-284)
10 20 30 40 50
pF1KB3 MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFI
: .: ::.::..::.:: : : :: .
XP_005 TSTAILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKL
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB3 TLVARNEDKLLQAKKEIEMHSINDKQV--VLCISVDVSQDYNQVENVIKQAQEKLGPVDM
.: .:: : . .:. . :. .. :.. : . . . . . .: ::.
XP_005 VLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLT-DSGAIVAAAAEILQCFGYVDI
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB3 LVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQ
::: ::.. : . : :.. .:.: ::.: : ..:.. .: .:: :.:: .:: :.
XP_005 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSIQGK
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB3 LGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRL
... .::.::: : ... . :. :.. :.. .:: :
XP_005 MSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGV
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB3 ISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTM
XP_005 MDTTTAQGRSPVEVAQDVLAAVGKKKKDVILADLLPSLAVYLRTLAPGLFFSLMASRARK
310 320 330 340 350 360
>>NP_001309209 (OMIM: 612833) dehydrogenase/reductase SD (289 aa)
initn: 256 init1: 177 opt: 296 Z-score: 369.1 bits: 76.4 E(85289): 8e-14
Smith-Waterman score: 305; 27.7% identity (59.8% similar) in 264 aa overlap (35-294:3-234)
10 20 30 40 50 60
pF1KB3 AAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVAR
: :::.:::::. .: . : :. ..: ::
NP_001 MVVWVTGASSGIGEELAYQLSKLGVSLVLSAR
10 20 30
70 80 90 100 110 120
pF1KB3 NEDKLLQAKKE-IEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAG
.: ..:.. .: ....:.. : . .:.. : .. : . : . ...: .:.::: .:
NP_001 RVHELERVKRRCLENGNLKEKDI-LVLPLDLT-DTGSHEAATKAVLQEFGRIDILVNNGG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 MAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGF
:. . : ......:. .::::.: .. :. : ::. :.:: :.: : ...
NP_001 MSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB3 TAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTS
.: ::: :.::. ..:. :. : ::. :
NP_001 IGYCASKHALRGFFNGLRTELATY--------------PGIIVSN---------------
160 170 180
250 260 270 280 290 300
pF1KB3 VCKPEQVAKQIVKDAIQGNFNSSLGSDG---YMLSALTCGMAPVTSITEGLQQVVTMGLF
.: : : ..::.... :. ....:..: . ... : . :... :..:
NP_001 IC-PGPVQSNIVENSLAGEVTKTIGNNGDQSHKMTTSRCVRLMLISMANDLKEVWISEQP
190 200 210 220 230 240
310 320 330
pF1KB3 RTIALFYLGSFDSIVRRCMMQREKSENADKTA
NP_001 FLLVTYLWQYMPTWAWWITNKMGKKRIENFKSGVDADSSYFKIFKTKHD
250 260 270 280
332 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:11:21 2016 done: Sat Nov 5 05:11:22 2016
Total Scan time: 7.720 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]