Result of FASTA (omim) for
pF1KB3488
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3488, 350 aa
1>>>pF1KB3488 350 - 350 aa - 350 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1889+/-0.000381; mu= 16.7603+/- 0.024
mean_var=63.4650+/-12.767, 0's: 0 Z-trim(111.2): 61 B-trim: 1045 in 1/54
Lambda= 0.160993
statistics sampled from 19628 (19689) to 19628 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.231), width: 16
Scan time: 7.880
The best scores are: opt bits E(85289)
NP_006627 (OMIM: 604887) bifunctional methylenetet ( 350) 2260 533.8 2.1e-151
XP_006711987 (OMIM: 604887) PREDICTED: bifunctiona ( 248) 1623 385.8 5.5e-107
NP_001138450 (OMIM: 614047) probable bifunctional ( 347) 1546 368.0 1.8e-101
NP_001004346 (OMIM: 614047) probable bifunctional ( 289) 1481 352.8 5.3e-97
XP_016863707 (OMIM: 614047) PREDICTED: probable bi ( 456) 1360 324.8 2.2e-88
XP_016863713 (OMIM: 614047) PREDICTED: probable bi ( 327) 1333 318.5 1.3e-86
XP_016863715 (OMIM: 614047) PREDICTED: probable bi ( 295) 1295 309.6 5.4e-84
XP_016863714 (OMIM: 614047) PREDICTED: probable bi ( 295) 1295 309.6 5.4e-84
XP_005265747 (OMIM: 614047) PREDICTED: probable bi ( 295) 1295 309.6 5.4e-84
XP_016863710 (OMIM: 614047) PREDICTED: probable bi ( 389) 1126 270.5 4.5e-72
XP_016863709 (OMIM: 614047) PREDICTED: probable bi ( 389) 1123 269.8 7.3e-72
XP_016863708 (OMIM: 614047) PREDICTED: probable bi ( 408) 1119 268.8 1.4e-71
XP_016863712 (OMIM: 614047) PREDICTED: probable bi ( 376) 1116 268.1 2.2e-71
XP_016863711 (OMIM: 614047) PREDICTED: probable bi ( 386) 1115 267.9 2.6e-71
XP_016863724 (OMIM: 614047) PREDICTED: probable bi ( 220) 1095 263.1 4.1e-70
XP_016863719 (OMIM: 614047) PREDICTED: probable bi ( 228) 1061 255.2 1e-67
XP_016863721 (OMIM: 614047) PREDICTED: probable bi ( 228) 1058 254.5 1.6e-67
XP_016863720 (OMIM: 614047) PREDICTED: probable bi ( 228) 1058 254.5 1.6e-67
XP_016863718 (OMIM: 614047) PREDICTED: probable bi ( 228) 1058 254.5 1.6e-67
XP_016863717 (OMIM: 614047) PREDICTED: probable bi ( 247) 1054 253.6 3.3e-67
XP_016863723 (OMIM: 614047) PREDICTED: probable bi ( 225) 1050 252.7 5.8e-67
XP_016863722 (OMIM: 614047) PREDICTED: probable bi ( 226) 909 219.9 4.2e-57
NP_005947 (OMIM: 172460,601634) C-1-tetrahydrofola ( 935) 514 128.5 5.7e-29
XP_016866193 (OMIM: 611427) PREDICTED: monofunctio ( 912) 241 65.1 6.9e-10
XP_011534033 (OMIM: 611427) PREDICTED: monofunctio ( 920) 241 65.1 6.9e-10
NP_056255 (OMIM: 611427) monofunctional C1-tetrahy ( 978) 238 64.4 1.2e-09
XP_005266964 (OMIM: 611427) PREDICTED: monofunctio ( 986) 238 64.4 1.2e-09
NP_001229697 (OMIM: 611427) monofunctional C1-tetr ( 913) 229 62.3 4.8e-09
XP_011534032 (OMIM: 611427) PREDICTED: monofunctio ( 921) 229 62.3 4.8e-09
XP_005266968 (OMIM: 611427) PREDICTED: monofunctio ( 607) 226 61.5 5.5e-09
XP_011534040 (OMIM: 611427) PREDICTED: monofunctio ( 710) 226 61.6 6.2e-09
XP_011534039 (OMIM: 611427) PREDICTED: monofunctio ( 712) 226 61.6 6.3e-09
XP_016866197 (OMIM: 611427) PREDICTED: monofunctio ( 752) 226 61.6 6.6e-09
XP_011534031 (OMIM: 611427) PREDICTED: monofunctio ( 955) 226 61.6 8e-09
XP_016866191 (OMIM: 611427) PREDICTED: monofunctio ( 979) 226 61.6 8.2e-09
NP_001229696 (OMIM: 611427) monofunctional C1-tetr ( 979) 226 61.6 8.2e-09
XP_016866192 (OMIM: 611427) PREDICTED: monofunctio ( 979) 226 61.6 8.2e-09
XP_005266967 (OMIM: 611427) PREDICTED: monofunctio ( 987) 226 61.6 8.2e-09
XP_016866196 (OMIM: 611427) PREDICTED: monofunctio ( 868) 225 61.4 8.7e-09
XP_016866194 (OMIM: 611427) PREDICTED: monofunctio ( 876) 225 61.4 8.7e-09
XP_011534036 (OMIM: 611427) PREDICTED: monofunctio ( 876) 225 61.4 8.7e-09
NP_001229698 (OMIM: 611427) monofunctional C1-tetr ( 275) 208 57.2 5.1e-08
XP_016866195 (OMIM: 611427) PREDICTED: monofunctio ( 869) 213 58.6 6e-08
XP_011534035 (OMIM: 611427) PREDICTED: monofunctio ( 877) 213 58.6 6e-08
XP_011534034 (OMIM: 611427) PREDICTED: monofunctio ( 877) 213 58.6 6e-08
>>NP_006627 (OMIM: 604887) bifunctional methylenetetrahy (350 aa)
initn: 2260 init1: 2260 opt: 2260 Z-score: 2839.1 bits: 533.8 E(85289): 2.1e-151
Smith-Waterman score: 2260; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)
10 20 30 40 50 60
pF1KB3 MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 NNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 WEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 KKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQ
250 260 270 280 290 300
310 320 330 340 350
pF1KB3 KAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
310 320 330 340 350
>>XP_006711987 (OMIM: 604887) PREDICTED: bifunctional me (248 aa)
initn: 1623 init1: 1623 opt: 1623 Z-score: 2041.8 bits: 385.8 E(85289): 5.5e-107
Smith-Waterman score: 1623; 100.0% identity (100.0% similar) in 248 aa overlap (103-350:1-248)
80 90 100 110 120 130
pF1KB3 ILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQ
::::::::::::::::::::::::::::::
XP_006 MKPASISEEELLNLINKLNNDDNVDGLLVQ
10 20 30
140 150 160 170 180 190
pF1KB3 LPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTL
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB3 GKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVIS
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB3 AAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGV
160 170 180 190 200 210
320 330 340 350
pF1KB3 GPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
::::::::::::::::::::::::::::::::::::::
XP_006 GPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
220 230 240
>>NP_001138450 (OMIM: 614047) probable bifunctional meth (347 aa)
initn: 1531 init1: 1531 opt: 1546 Z-score: 1942.9 bits: 368.0 E(85289): 1.8e-101
Smith-Waterman score: 1546; 68.5% identity (88.8% similar) in 330 aa overlap (3-332:18-346)
10 20 30 40
pF1KB3 MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKL
: .: . : . :.. : .: :. ..::.::..::: ..
NP_001 MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSA-FRGFRSSGVRHEAIIISGTEM
10 20 30 40 50
50 60 70 80 90 100
pF1KB3 AQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKP
:..:..:... :: ::. ::.:::::.::::.:::::.:: :: :::..::: :: :.::
NP_001 AKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB3 ASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRM
..:.::::.. ..:: : :.:.:::::::.:.::: :::...:.:::::::.::.::.
NP_001 KDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB3 CLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGD
::::.:..::: .:::::::::: :.::::::::::::::::::::::::: :::::::
NP_001 CLDQHSLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGD
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB3 ATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTA
:::::.:::::::::: :: ::::.: :::::.:::.::.:::::::::::: ::::::.
NP_001 ATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVTG
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB3 KPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKEL
: :::::::::.:..:::.::::::::::::::::.:::..::::..
NP_001 KTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY
300 310 320 330 340
350
pF1KB3 GVATN
>>NP_001004346 (OMIM: 614047) probable bifunctional meth (289 aa)
initn: 1452 init1: 1452 opt: 1481 Z-score: 1862.5 bits: 352.8 E(85289): 5.3e-97
Smith-Waterman score: 1481; 73.6% identity (92.4% similar) in 288 aa overlap (45-332:1-288)
20 30 40 50 60 70
pF1KB3 LQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVIL
.:..:..:... :: ::. ::.:::::.::
NP_001 MAKHIQKEIQRGVESWVSLGNRRPHLSIIL
10 20 30
80 90 100 110 120 130
pF1KB3 VGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLP
::.:::::.:: :: :::..::: :: :.:: ..:.::::.. ..:: : :.:.:::::
NP_001 VGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB3 LPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGK
::.:.::: :::...:.:::::::.::.::.::::.:..::: .:::::::::: :.::
NP_001 LPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGK
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 NVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAA
::::::::::::::::::::::: ::::::::::::.:::::::::: :: ::::.: ::
NP_001 NVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 GIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGP
:::.:::.::.:::::::::::: ::::::.: :::::::::.:..:::.::::::::::
NP_001 GIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEAVKKKAGFITPVPGGVGP
220 230 240 250 260 270
320 330 340 350
pF1KB3 MTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
::::::.:::..::::..
NP_001 MTVAMLLKNTLLAAKKIIY
280
>>XP_016863707 (OMIM: 614047) PREDICTED: probable bifunc (456 aa)
initn: 1357 init1: 1357 opt: 1360 Z-score: 1707.7 bits: 324.8 E(85289): 2.2e-88
Smith-Waterman score: 1360; 67.8% identity (87.5% similar) in 295 aa overlap (3-297:121-414)
10 20 30
pF1KB3 MAATSLMSALAARLLQPAHSCSLRLRPFHLAA
: .: . : . :.. : .: :. ..
XP_016 EVEPQSGSRGSAAMTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSA-FRGFRSSG
100 110 120 130 140
40 50 60 70 80 90
pF1KB3 VRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAA
::.::..::: ..:..:..:... :: ::. ::.:::::.::::.:::::.:: :: :::
XP_016 VRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAA
150 160 170 180 190 200
100 110 120 130 140 150
pF1KB3 AVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDK
..::: :: :.:: ..:.::::.. ..:: : :.:.:::::::.:.::: :::...:.:
XP_016 SAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEK
210 220 230 240 250 260
160 170 180 190 200 210
pF1KB3 DVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAML
::::::.::.::.::::.:..::: .:::::::::: :.::::::::::::::::::::
XP_016 DVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAML
270 280 290 300 310 320
220 230 240 250 260 270
pF1KB3 LHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVI
::::: ::::::::::::.:::::::::: :: ::::.: :::::.:::.::.:::::::
XP_016 LHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVI
330 340 350 360 370 380
280 290 300 310 320 330
pF1KB3 DVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVL
::::: ::::::.: ::::::::::
XP_016 DVGINYVHDPVTGKTKLVGDVDFEGCHDNEHLNIFRKLVETSRFSNQMNLLKRKLALSLQ
390 400 410 420 430 440
>>XP_016863713 (OMIM: 614047) PREDICTED: probable bifunc (327 aa)
initn: 1333 init1: 1333 opt: 1333 Z-score: 1675.9 bits: 318.5 E(85289): 1.3e-86
Smith-Waterman score: 1333; 72.6% identity (91.3% similar) in 263 aa overlap (35-297:23-285)
10 20 30 40 50 60
pF1KB3 SLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASG
.::..::: ..:..:..:... :: ::. :
XP_016 MARLTAVVRGHAWGHGITFFFEHEAIIISGTEMAKHIQKEIQRGVESWVSLG
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 NKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDD
:.:::::.::::.:::::.:: :: :::..::: :: :.:: ..:.::::.. ..:: :
XP_016 NRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 NVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEII
:.:.:::::::.:.::: :::...:.:::::::.::.::.::::.:..::: .:::::
XP_016 RVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEII
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 KRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHT
::::: :.::::::::::::::::::::::::: ::::::::::::.:::::::::: ::
XP_016 KRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 ILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGY
::::.: :::::.:::.::.:::::::::::: ::::::.: ::::::::::
XP_016 QLADIIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEGCHDNEHL
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 ITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
XP_016 NIFRKLVETSRFSNQMNLLKRKLALSLQFQEVWDP
300 310 320
>>XP_016863715 (OMIM: 614047) PREDICTED: probable bifunc (295 aa)
initn: 1295 init1: 1295 opt: 1295 Z-score: 1628.9 bits: 309.6 E(85289): 5.4e-84
Smith-Waterman score: 1295; 73.5% identity (91.3% similar) in 253 aa overlap (45-297:1-253)
20 30 40 50 60 70
pF1KB3 LQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVIL
.:..:..:... :: ::. ::.:::::.::
XP_016 MAKHIQKEIQRGVESWVSLGNRRPHLSIIL
10 20 30
80 90 100 110 120 130
pF1KB3 VGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLP
::.:::::.:: :: :::..::: :: :.:: ..:.::::.. ..:: : :.:.:::::
XP_016 VGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB3 LPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGK
::.:.::: :::...:.:::::::.::.::.::::.:..::: .:::::::::: :.::
XP_016 LPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGK
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 NVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAA
::::::::::::::::::::::: ::::::::::::.:::::::::: :: ::::.: ::
XP_016 NVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 GIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGP
:::.:::.::.:::::::::::: ::::::.: ::::::::::
XP_016 GIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEGCHDNEHLNIFRKLVETS
220 230 240 250 260 270
320 330 340 350
pF1KB3 MTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
XP_016 RFSNQMNLLKRKLALSLQFQEVWDP
280 290
>>XP_016863714 (OMIM: 614047) PREDICTED: probable bifunc (295 aa)
initn: 1295 init1: 1295 opt: 1295 Z-score: 1628.9 bits: 309.6 E(85289): 5.4e-84
Smith-Waterman score: 1295; 73.5% identity (91.3% similar) in 253 aa overlap (45-297:1-253)
20 30 40 50 60 70
pF1KB3 LQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVIL
.:..:..:... :: ::. ::.:::::.::
XP_016 MAKHIQKEIQRGVESWVSLGNRRPHLSIIL
10 20 30
80 90 100 110 120 130
pF1KB3 VGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLP
::.:::::.:: :: :::..::: :: :.:: ..:.::::.. ..:: : :.:.:::::
XP_016 VGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB3 LPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGK
::.:.::: :::...:.:::::::.::.::.::::.:..::: .:::::::::: :.::
XP_016 LPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGK
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 NVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAA
::::::::::::::::::::::: ::::::::::::.:::::::::: :: ::::.: ::
XP_016 NVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 GIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGP
:::.:::.::.:::::::::::: ::::::.: ::::::::::
XP_016 GIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEGCHDNEHLNIFRKLVETS
220 230 240 250 260 270
320 330 340 350
pF1KB3 MTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
XP_016 RFSNQMNLLKRKLALSLQFQEVWDP
280 290
>>XP_005265747 (OMIM: 614047) PREDICTED: probable bifunc (295 aa)
initn: 1295 init1: 1295 opt: 1295 Z-score: 1628.9 bits: 309.6 E(85289): 5.4e-84
Smith-Waterman score: 1295; 73.5% identity (91.3% similar) in 253 aa overlap (45-297:1-253)
20 30 40 50 60 70
pF1KB3 LQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVIL
.:..:..:... :: ::. ::.:::::.::
XP_005 MAKHIQKEIQRGVESWVSLGNRRPHLSIIL
10 20 30
80 90 100 110 120 130
pF1KB3 VGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLP
::.:::::.:: :: :::..::: :: :.:: ..:.::::.. ..:: : :.:.:::::
XP_005 VGDNPASHTYVRNKIRAASAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLP
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB3 LPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGK
::.:.::: :::...:.:::::::.::.::.::::.:..::: .:::::::::: :.::
XP_005 LPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGK
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB3 NVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAA
::::::::::::::::::::::: ::::::::::::.:::::::::: :: ::::.: ::
XP_005 NVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 GIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGP
:::.:::.::.:::::::::::: ::::::.: ::::::::::
XP_005 GIPKLITSDMVKEGAAVIDVGINYVHDPVTGKTKLVGDVDFEGCHDNEHLNIFRKLVETS
220 230 240 250 260 270
320 330 340 350
pF1KB3 MTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
XP_005 RFSNQMNLLKRKLALSLQFQEVWDP
280 290
>>XP_016863710 (OMIM: 614047) PREDICTED: probable bifunc (389 aa)
initn: 1111 init1: 1111 opt: 1126 Z-score: 1415.0 bits: 270.5 E(85289): 4.5e-72
Smith-Waterman score: 1126; 63.8% identity (86.0% similar) in 257 aa overlap (3-259:121-376)
10 20 30
pF1KB3 MAATSLMSALAARLLQPAHSCSLRLRPFHLAA
: .: . : . :.. : .: :. ..
XP_016 EVEPQSGSRGSAAMTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSA-FRGFRSSG
100 110 120 130 140
40 50 60 70 80 90
pF1KB3 VRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAA
::.::..::: ..:..:..:... :: ::. ::.:::::.::::.:::::.:: :: :::
XP_016 VRHEAIIISGTEMAKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAA
150 160 170 180 190 200
100 110 120 130 140 150
pF1KB3 AVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDK
..::: :: :.:: ..:.::::.. ..:: : :.:.:::::::.:.::: :::...:.:
XP_016 SAVGICSELILKPKDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEK
210 220 230 240 250 260
160 170 180 190 200 210
pF1KB3 DVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAML
::::::.::.::.::::.:..::: .:::::::::: :.::::::::::::::::::::
XP_016 DVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAML
270 280 290 300 310 320
220 230 240 250 260 270
pF1KB3 LHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVI
::::: ::::::::::::.:::::::::: :: ::::.: ::. :..
XP_016 LHTDGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAAAPHVSHPYPETSIQAQI
330 340 350 360 370 380
280 290 300 310 320 330
pF1KB3 DVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVL
350 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:10:50 2016 done: Sat Nov 5 05:10:51 2016
Total Scan time: 7.880 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]