FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3488, 350 aa
  1>>>pF1KB3488 350 - 350 aa - 350 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4270+/-0.000922; mu= 15.4528+/- 0.055
 mean_var=61.3718+/-12.230, 0's: 0 Z-trim(104.3): 19  B-trim: 3 in 1/50
 Lambda= 0.163716
 statistics sampled from 7808 (7821) to 7808 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.24), width:  16
 Scan time:  2.610

The best scores are:                                      opt bits E(32554)
CCDS1935.2 MTHFD2 gene_id:10797|Hs108|chr2         ( 350) 2260 542.4 2.1e-154
CCDS47075.1 MTHFD2L gene_id:441024|Hs108|chr4      ( 347) 1546 373.8 1.2e-103
CCDS9763.1 MTHFD1 gene_id:4522|Hs108|chr14         ( 935)  514 130.2 6.8e-30


>>CCDS1935.2 MTHFD2 gene_id:10797|Hs108|chr2              (350 aa)
 initn: 2260 init1: 2260 opt: 2260  Z-score: 2885.7  bits: 542.4 E(32554): 2.1e-154
Smith-Waterman score: 2260; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)

               10        20        30        40        50        60
pF1KB3 MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEW
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 VASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 VASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 NNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 NNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 WEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 WEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 KKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 KKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQ
              250       260       270       280       290       300

              310       320       330       340       350
pF1KB3 KAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
       ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 KAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
              310       320       330       340       350

>>CCDS47075.1 MTHFD2L gene_id:441024|Hs108|chr4           (347 aa)
 initn: 1531 init1: 1531 opt: 1546  Z-score: 1974.3  bits: 373.8 E(32554): 1.2e-103
Smith-Waterman score: 1546; 68.5% identity (88.8% similar) in 330 aa overlap (3-332:18-346)

                              10        20        30        40     
pF1KB3                MAATSLMSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKL
                        : .:  . :  .  :..  :  .: :. ..::.::..::: ..
CCDS47 MTVPVRGFSLLRGRLGRAPALGRSTAPSVRAPGEPGSA-FRGFRSSGVRHEAIIISGTEM
               10        20        30         40        50         

          50        60        70        80        90       100     
pF1KB3 AQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKP
       :..:..:... :: ::. ::.:::::.::::.:::::.:: :: :::..::: :: :.::
CCDS47 AKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILKP
      60        70        80        90       100       110         

         110       120       130       140       150       160     
pF1KB3 ASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRM
        ..:.::::.. ..:: :  :.:.:::::::.:.::: :::...:.:::::::.::.::.
CCDS47 KDVSQEELLDVTDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRL
     120       130       140       150       160       170         

         170       180       190       200       210       220     
pF1KB3 CLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGD
       ::::.:..:::  .:::::::::: :.::::::::::::::::::::::::: :::::::
CCDS47 CLDQHSLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGD
     180       190       200       210       220       230         

         230       240       250       260       270       280     
pF1KB3 ATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTA
       :::::.:::::::::: :: ::::.: :::::.:::.::.:::::::::::: ::::::.
CCDS47 ATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPKLITSDMVKEGAAVIDVGINYVHDPVTG
     240       250       260       270       280       290         

         290       300       310       320       330       340     
pF1KB3 KPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKEL
       : :::::::::.:..:::.::::::::::::::::.:::..::::..             
CCDS47 KTKLVGDVDFEAVKKKAGFITPVPGGVGPMTVAMLLKNTLLAAKKIIY            
     300       310       320       330       340                   

         350
pF1KB3 GVATN

>>CCDS9763.1 MTHFD1 gene_id:4522|Hs108|chr14              (935 aa)
 initn: 672 init1: 186 opt: 514  Z-score: 650.1  bits: 130.2 E(32554): 6.8e-30
Smith-Waterman score: 670; 39.1% identity (69.1% similar) in 304 aa overlap (37-332:4-295)

         10        20        30        40        50        60      
pF1KB3 MSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVAS-GN
                                     : ...:.... ::. .....: .   .  .
CCDS97                            MAPAEILNGKEISAQIRARLKNQVTQLKEQVPG
                                          10        20        30   

          70        80        90       100       110       120     
pF1KB3 KRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDN
         :.:... ::.   :. :.  : .::  .::..  :  : . .: :... :..::.:..
CCDS97 FTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKATHIKLPRTTTESEVMKYITSLNEDST
            40        50        60        70        80        90   

         130         140       150       160       170         180 
pF1KB3 VDGLLVQLPLPEH--IDERRICNAVSPDKDVDGFHVINVGRMCLDQYS--MLPATPWGVW
       : :.::::::  .  :. ... ::..:.:::::.  ::.:..   . .  ..: :: :  
CCDS97 VHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGKLARGDLNDCFIPCTPKGCL
           100       110       120       130       140       150   

             190       200       210       220       230       240 
pF1KB3 EIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLK
       :.::.::.:  :...::.:::: :: :.  ::  .        .::::  :  :   .: 
CCDS97 ELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWN--------NATVTTCHSKT--AHLD
           160       170       180               190         200   

             250       260       270       280          290        
pF1KB3 KHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKP---KLVGDVDFEGV
       ...  .::.. :.: :... .. :: :: ::: ::: : :    ::   :.:::: .. .
CCDS97 EEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDD--KKPNGRKVVGDVAYDEA
           210       220       230       240         250       260 

      300       310       320       330       340       350        
pF1KB3 RQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN        
       ...:..:::::::::::::::::..:. .::. :                          
CCDS97 KERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKPGKWMIQYNNLNLKTPVPSDID
             270       280       290       300       310       320 

CCDS97 ISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTP
             330       340       350       360       370       380 




350 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:10:49 2016 done: Sat Nov  5 05:10:50 2016
 Total Scan time:  2.610 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]