Result of FASTA (omim) for
pF1KB3479
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3479, 421 aa
1>>>pF1KB3479 421 - 421 aa - 421 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3762+/-0.000384; mu= 13.6812+/- 0.024
mean_var=128.6056+/-27.080, 0's: 0 Z-trim(115.9): 350 B-trim: 1089 in 1/54
Lambda= 0.113095
statistics sampled from 26202 (26611) to 26202 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.312), width: 16
Scan time: 8.290
The best scores are: opt bits E(85289)
NP_056456 (OMIM: 606085) testin isoform 1 [Homo sa ( 421) 3035 506.6 4.7e-143
NP_690042 (OMIM: 606085) testin isoform 2 [Homo sa ( 412) 2979 497.5 2.6e-140
XP_005250315 (OMIM: 606085) PREDICTED: testin isof ( 336) 2430 407.8 2.1e-113
NP_055398 (OMIM: 604859) LIM and cysteine-rich dom ( 365) 1328 228.1 2.9e-59
XP_011531951 (OMIM: 604859) PREDICTED: LIM and cys ( 371) 1302 223.8 5.6e-58
NP_001265162 (OMIM: 604859) LIM and cysteine-rich ( 292) 1073 186.4 8.4e-47
NP_001265163 (OMIM: 604859) LIM and cysteine-rich ( 253) 868 152.8 8.8e-37
NP_001265164 (OMIM: 604859) LIM and cysteine-rich ( 247) 826 146.0 1e-34
XP_011531742 (OMIM: 608501,613832) PREDICTED: pric ( 679) 727 130.2 1.5e-29
XP_016861287 (OMIM: 608501,613832) PREDICTED: pric ( 844) 727 130.3 1.8e-29
NP_942559 (OMIM: 608501,613832) prickle-like prote ( 844) 727 130.3 1.8e-29
XP_011531739 (OMIM: 608501,613832) PREDICTED: pric ( 874) 727 130.3 1.8e-29
XP_011531738 (OMIM: 608501,613832) PREDICTED: pric ( 874) 727 130.3 1.8e-29
XP_011531737 (OMIM: 608501,613832) PREDICTED: pric ( 900) 727 130.4 1.9e-29
XP_011531736 (OMIM: 608501,613832) PREDICTED: pric ( 930) 727 130.4 1.9e-29
XP_011531735 (OMIM: 608501,613832) PREDICTED: pric ( 936) 727 130.4 1.9e-29
XP_011531734 (OMIM: 608501,613832) PREDICTED: pric ( 966) 727 130.4 2e-29
XP_016861288 (OMIM: 608501,613832) PREDICTED: pric ( 720) 725 129.9 2e-29
XP_011531740 (OMIM: 608501,613832) PREDICTED: pric ( 757) 725 130.0 2.1e-29
NP_001294908 (OMIM: 300111) prickle-like protein 3 ( 547) 717 128.5 4e-29
NP_006141 (OMIM: 300111) prickle-like protein 3 is ( 615) 717 128.6 4.4e-29
NP_694571 (OMIM: 608500,612437) prickle-like prote ( 831) 701 126.1 3.3e-28
XP_016874329 (OMIM: 608500,612437) PREDICTED: pric ( 831) 701 126.1 3.3e-28
XP_016874327 (OMIM: 608500,612437) PREDICTED: pric ( 831) 701 126.1 3.3e-28
NP_001138354 (OMIM: 608500,612437) prickle-like pr ( 831) 701 126.1 3.3e-28
XP_016874328 (OMIM: 608500,612437) PREDICTED: pric ( 831) 701 126.1 3.3e-28
XP_011536248 (OMIM: 608500,612437) PREDICTED: pric ( 831) 701 126.1 3.3e-28
XP_011536249 (OMIM: 608500,612437) PREDICTED: pric ( 831) 701 126.1 3.3e-28
NP_001138355 (OMIM: 608500,612437) prickle-like pr ( 831) 701 126.1 3.3e-28
NP_001138353 (OMIM: 608500,612437) prickle-like pr ( 831) 701 126.1 3.3e-28
NP_037529 (OMIM: 611389) prickle-like protein 4 [H ( 384) 448 84.5 5.1e-16
NP_004459 (OMIM: 602790) four and a half LIM domai ( 280) 330 65.1 2.5e-10
XP_011537495 (OMIM: 605906,609452) PREDICTED: LIM ( 463) 333 65.8 2.6e-10
XP_016871096 (OMIM: 605906,609452) PREDICTED: LIM ( 463) 333 65.8 2.6e-10
NP_001073583 (OMIM: 605906,609452) LIM domain-bind ( 617) 333 65.9 3.2e-10
XP_005269523 (OMIM: 605906,609452) PREDICTED: LIM ( 664) 333 65.9 3.4e-10
XP_011537492 (OMIM: 605906,609452) PREDICTED: LIM ( 680) 333 66.0 3.4e-10
XP_016871095 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 333 66.0 3.6e-10
XP_011537490 (OMIM: 605906,609452) PREDICTED: LIM ( 743) 333 66.0 3.6e-10
XP_011537489 (OMIM: 605906,609452) PREDICTED: LIM ( 748) 333 66.0 3.7e-10
XP_011537486 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 333 66.0 3.9e-10
XP_011537487 (OMIM: 605906,609452) PREDICTED: LIM ( 811) 333 66.0 3.9e-10
NP_963849 (OMIM: 602633) four and a half LIM domai ( 279) 322 63.8 6.2e-10
NP_001305823 (OMIM: 602633) four and a half LIM do ( 279) 322 63.8 6.2e-10
NP_963851 (OMIM: 602633) four and a half LIM domai ( 279) 322 63.8 6.2e-10
NP_001305825 (OMIM: 602633) four and a half LIM do ( 279) 322 63.8 6.2e-10
XP_011509100 (OMIM: 602633) PREDICTED: four and a ( 279) 322 63.8 6.2e-10
NP_001441 (OMIM: 602633) four and a half LIM domai ( 279) 322 63.8 6.2e-10
NP_001305824 (OMIM: 602633) four and a half LIM do ( 279) 322 63.8 6.2e-10
NP_001034581 (OMIM: 602633) four and a half LIM do ( 279) 322 63.8 6.2e-10
>>NP_056456 (OMIM: 606085) testin isoform 1 [Homo sapien (421 aa)
initn: 3035 init1: 3035 opt: 3035 Z-score: 2689.3 bits: 506.6 E(85289): 4.7e-143
Smith-Waterman score: 3035; 100.0% identity (100.0% similar) in 421 aa overlap (1-421:1-421)
10 20 30 40 50 60
pF1KB3 MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 RKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM
370 380 390 400 410 420
pF1KB3 S
:
NP_056 S
>>NP_690042 (OMIM: 606085) testin isoform 2 [Homo sapien (412 aa)
initn: 2979 init1: 2979 opt: 2979 Z-score: 2640.0 bits: 497.5 E(85289): 2.6e-140
Smith-Waterman score: 2979; 100.0% identity (100.0% similar) in 412 aa overlap (10-421:1-412)
10 20 30 40 50 60
pF1KB3 MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 RKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 RKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 ALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 ALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 KYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCK
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 LSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRM
360 370 380 390 400 410
pF1KB3 S
:
NP_690 S
>>XP_005250315 (OMIM: 606085) PREDICTED: testin isoform (336 aa)
initn: 2430 init1: 2430 opt: 2430 Z-score: 2157.1 bits: 407.8 E(85289): 2.1e-113
Smith-Waterman score: 2430; 100.0% identity (100.0% similar) in 336 aa overlap (86-421:1-336)
60 70 80 90 100 110
pF1KB3 SNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAP
::::::::::::::::::::::::::::::
XP_005 MYKRNVMILTNPVAAKKNVSINTVTYEWAP
10 20 30
120 130 140 150 160 170
pF1KB3 PVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEM
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB3 EQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYS
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB3 CYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCD
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB3 SEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVK
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB3 NHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVE
280 290 300 310 320 330
420
pF1KB3 CKKRMS
::::::
XP_005 CKKRMS
>>NP_055398 (OMIM: 604859) LIM and cysteine-rich domains (365 aa)
initn: 1332 init1: 995 opt: 1328 Z-score: 1184.9 bits: 228.1 E(85289): 2.9e-59
Smith-Waterman score: 1328; 51.1% identity (77.2% similar) in 356 aa overlap (2-352:7-359)
10 20 30 40 50
pF1KB3 MDLENKVKKMGLGHEQGF-GAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVL
::. ::::.::. :. :. :: :: : ::: : :::::..:::.::.: .
NP_055 MAKVAKDLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 LSNEEDRKVGKLFEDTKYTTLIAKLKS-DGIPMYKRNVMILTNPVAAKKNVSINTVTYEW
. :.:::.:.:. :.::.:: :..:. ::: .:::: ::.:::.:. :. ...:.::::
NP_055 SDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEW
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 APPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVK
::: .: :. :::...:::::::.:.::: ::..:: .::: .:::::.:. : :.:
NP_055 APPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 EMEQFVKKYKSEALGVGDVKLPCE--MDAQGPKQMNIPGGDRSTPAAV-GAMEDKSAEHK
::.:::.:::::::::.: :: . . . ::.. : : ..: :.. :.. : : :
NP_055 LMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPS---K
190 200 210 220 230
240 250 260 270 280 290
pF1KB3 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG
...: : :: . .:..:..::::.: :::.::::. : : :::.:::::. .::
NP_055 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 RHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCK
::::.: .:::.::::.::...: ..:. :: ::: : :...:.:. :.... . .:
NP_055 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 PCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMV
:
NP_055 TCSKSKRS
360
>>XP_011531951 (OMIM: 604859) PREDICTED: LIM and cystein (371 aa)
initn: 1295 init1: 995 opt: 1302 Z-score: 1161.9 bits: 223.8 E(85289): 5.6e-58
Smith-Waterman score: 1302; 50.9% identity (77.3% similar) in 348 aa overlap (10-352:21-365)
10 20 30 40
pF1KB3 MDLENKVKKMGLGHEQGF-GAPCLKCKEKCEGFELHFWRKICRNCKCGQ
:.::. :. :. :: :: : ::: : :::::..:::.:
XP_011 MGYTYKVIERILEIGAFRPHMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 EEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKS-DGIPMYKRNVMILTNPVAAKKNVSIN
:.: . . :.:::.:.:. :.::.:: :..:. ::: .:::: ::.:::.:. :. ...
XP_011 EDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB3 TVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHEL
:.::::::: .: :. :::...:::::::.:.::: ::..:: .::: .:::::.:. :
XP_011 TITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 SPREVKEMEQFVKKYKSEALGVGDVKLPCE--MDAQGPKQMNIPGGDRSTPAAV-GAMED
:.: ::.:::.:::::::::.: :: . . . ::.. : : ..: :.. :.. :
XP_011 LENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSD
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB3 KSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKN
: :...: : :: . .:..:..::::.: :::.::::. : : :::.:::::.
XP_011 PS---KEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKD
250 260 270 280 290
290 300 310 320 330 340
pF1KB3 EKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVN
.::::::.: .:::.::::.::...: ..:. :: ::: : :...:.:. :....
XP_011 GAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTK
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB3 DKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFM
. .: :
XP_011 GQLLCPTCSKSKRS
360 370
>>NP_001265162 (OMIM: 604859) LIM and cysteine-rich doma (292 aa)
initn: 995 init1: 995 opt: 1073 Z-score: 961.3 bits: 186.4 E(85289): 8.4e-47
Smith-Waterman score: 1073; 50.7% identity (77.8% similar) in 288 aa overlap (69-352:2-286)
40 50 60 70 80 90
pF1KB3 KICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKS-DGIPMYKRNVMILTNP
:.::.:: :..:. ::: .:::: ::.:::
NP_001 MDSKYSTLTARVKGGDGIRIYKRNRMIMTNP
10 20 30
100 110 120 130 140 150
pF1KB3 VAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAH
.:. :. ...:.::::::: .: :. :::...:::::::.:.::: ::..:: .::: .
NP_001 IATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIY
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB3 DQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCE--MDAQGPKQMNIPGGDRST
:::::.:. : :.: ::.:::.:::::::::.: :: . . . ::.. : : ..:
NP_001 DQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB3 PAAV-GAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHEL
:.. :.. : : :...: : :: . .:..:..::::.: :::.::::. : :
NP_001 AATTNGSLSDPS---KEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEP
160 170 180 190 200
280 290 300 310 320 330
pF1KB3 LVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSI
:::.:::::. .::::::.: .:::.::::.::...: ..:. :: ::: : :...
NP_001 LVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQL
210 220 230 240 250 260
340 350 360 370 380 390
pF1KB3 LAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCC
:.:. :.... . .: :
NP_001 LSGRAYIVTKGQLLCPTCSKSKRS
270 280 290
>>NP_001265163 (OMIM: 604859) LIM and cysteine-rich doma (253 aa)
initn: 828 init1: 828 opt: 868 Z-score: 781.3 bits: 152.8 E(85289): 8.8e-37
Smith-Waterman score: 868; 49.8% identity (76.6% similar) in 231 aa overlap (125-352:20-247)
100 110 120 130 140 150
pF1KB3 TNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQL
:::...:::::::.:.::: ::..:: .::
NP_001 MFGMQGDVFGLRATFMEGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQL
10 20 30 40
160 170 180 190 200 210
pF1KB3 PAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCE--MDAQGPKQMNIPGGD
: .:::::.:. : :.: ::.:::.:::::::::.: :: . . . ::.. : :
NP_001 PIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGA
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB3 RSTPAAV-GAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTC
..: :.. :.. : : :...: : :: . .:..:..::::.: :::.::::. :
NP_001 ETTAATTNGSLSDPS---KEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKC
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB3 HELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDC
: :::.:::::. .::::::.: .:::.::::.::...: ..:. :: ::: : :
NP_001 SEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGC
170 180 190 200 210 220
340 350 360 370 380 390
pF1KB3 DSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLC
...:.:. :.... . .: :
NP_001 EQLLSGRAYIVTKGQLLCPTCSKSKRS
230 240 250
>>NP_001265164 (OMIM: 604859) LIM and cysteine-rich doma (247 aa)
initn: 785 init1: 500 opt: 826 Z-score: 744.4 bits: 146.0 E(85289): 1e-34
Smith-Waterman score: 826; 53.4% identity (78.0% similar) in 232 aa overlap (2-228:7-238)
10 20 30 40 50
pF1KB3 MDLENKVKKMGLGHEQGF-GAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVL
::. ::::.::. :. :. :: :: : ::: : :::::..:::.::.: .
NP_001 MAKVAKDLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 LSNEEDRKVGKLFEDTKYTTLIAKLKS-DGIPMYKRNVMILTNPVAAKKNVSINTVTYEW
. :.:::.:.:. :.::.:: :..:. ::: .:::: ::.:::.:. :. ...:.::::
NP_001 SDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEW
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 APPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVK
::: .: :. :::...:::::::.:.::: ::..:: .::: .:::::.:. : :.:
NP_001 APPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 EMEQFVKKYKSEALGVGDVKLPCE--MDAQGPKQMNIPGGDRSTPAAV-GAMEDKSAEHK
::.:::.:::::::::.: :: . . . ::.. : : ..: :.. :.. : : :
NP_001 LMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCG
NP_001 YKPVPLV
>>XP_011531742 (OMIM: 608501,613832) PREDICTED: prickle- (679 aa)
initn: 1136 init1: 711 opt: 727 Z-score: 651.4 bits: 130.2 E(85289): 1.5e-29
Smith-Waterman score: 1022; 37.3% identity (61.0% similar) in 408 aa overlap (11-416:53-402)
10 20 30 40
pF1KB3 MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKI
:::. . : :: : ..: :: :: ::::
XP_011 ADRRAPPAGRERPRAAPLRPAAAHLWPQLTGLGRIER-GQPCNACGDQCPGFALHKWRKI
30 40 50 60 70 80
50 60 70 80 90
pF1KB3 CRNCKCGQEEHDV-LLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVA
: .::: :::: : .. : .. ..::. : ..:: .
XP_011 CLHCKCPQEEHMVTVMPLEMEKTISKLMFD-----------------FQRNS-------T
90 100 110
100 110 120 130 140 150
pF1KB3 AKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQ
. . . : :.:: . ..::.. ::.:: : ..: : . : ::: .::: ::.
XP_011 SDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDN
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB3 DPSKCHELSPREVKEMEQFVKKYKSEALGVGDVK-LPCEMDAQGPKQMNIPGGDRSTPAA
. :. :. .: .:.. : .. : : :: :.:. .: :
XP_011 EVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVTM--------------------
180 190 200 210
220 230 240 250 260 270
pF1KB3 VGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDM
.::. : : ... :: :..: :::. ::: ::::..:.:::::.
XP_011 TGAI-------------CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDL
220 230 240 250 260
280 290 300 310 320 330
pF1KB3 IYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGE
:::... :.:::::. . :::::.:::.::..: :.::...::.::::::.:...:.:.
XP_011 IYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQ
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB3 IYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCL
:.: . .: : :. . .: :. : . : . ..::.. :::. :: :. :.: :
XP_011 RYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAHCKKSL
330 340 350 360 370 380
400 410 420
pF1KB3 IGQKFMPVEGMVFCSVECKKRMS
.:. :.: .:..::: :
XP_011 LGRPFLPKQGQIFCSRACSAGEDPNGSDSSDSAFQNARAKESRRSAKIGKNKGKTEEPML
390 400 410 420 430 440
>>XP_016861287 (OMIM: 608501,613832) PREDICTED: prickle- (844 aa)
initn: 967 init1: 711 opt: 727 Z-score: 650.2 bits: 130.3 E(85289): 1.8e-29
Smith-Waterman score: 880; 39.4% identity (65.1% similar) in 307 aa overlap (111-416:37-310)
90 100 110 120 130 140
pF1KB3 SDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGS
: :.:: . ..::.. ::.:: : ..:
XP_016 LEMEKTISKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEEKVPYVNS
10 20 30 40 50 60
150 160 170 180 190
pF1KB3 EGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVK-LPCEMD
: . : ::: .::: ::.. :. :. .: .:.. : .. : : :: :.:. .: :
XP_016 PGEKLRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVTM-
70 80 90 100 110 120
200 210 220 230 240 250
pF1KB3 AQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDK
.::. : : ... :: :..: :::.
XP_016 -------------------TGAI-------------CEQCGGQINGGDIAVFASRAGHGV
130 140 150
260 270 280 290 300 310
pF1KB3 LWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQ
::: ::::..:.:::::.:::... :.:::::. . :::::.:::.::..: :.::..
XP_016 CWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGR
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB3 NWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNN
.::.::::::.:...:.:. :.: . .: : :. . .: :. : . : . ..::..
XP_016 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG
220 230 240 250 260 270
380 390 400 410 420
pF1KB3 FSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRMS
:::. :: :. :.: :.:. :.: .:..::: :
XP_016 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGEDPNGSDSSDSAFQNARAKE
280 290 300 310 320 330
XP_016 SRRSAKIGKNKGKTEEPMLNQHSQLQVSSNRLSADVDPLSLQMDMLSLSSQTPSLNRDPI
340 350 360 370 380 390
421 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:08:55 2016 done: Sat Nov 5 05:08:56 2016
Total Scan time: 8.290 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]