Result of FASTA (omim) for
pF1KB3458
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3458, 1117 aa
1>>>pF1KB3458 1117 - 1117 aa - 1117 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.7966+/-0.000416; mu= -5.3119+/- 0.026
mean_var=437.0813+/-91.833, 0's: 0 Z-trim(123.7): 137 B-trim: 2539 in 2/59
Lambda= 0.061347
statistics sampled from 43896 (44068) to 43896 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.517), width: 16
Scan time: 15.250
The best scores are: opt bits E(85289)
XP_016866543 (OMIM: 610322) PREDICTED: transcripti (1117) 7721 698.5 5.6e-200
XP_016866541 (OMIM: 610322) PREDICTED: transcripti (1129) 6558 595.6 5.5e-169
XP_016866542 (OMIM: 610322) PREDICTED: transcripti (1129) 6558 595.6 5.5e-169
XP_016866540 (OMIM: 610322) PREDICTED: transcripti (1171) 5625 513.0 4.1e-144
NP_001284502 (OMIM: 610322) transcriptional-regula (1220) 4043 373.0 5.9e-102
XP_016866537 (OMIM: 610322) PREDICTED: transcripti (1220) 4043 373.0 5.9e-102
NP_277037 (OMIM: 610322) transcriptional-regulatin (1200) 4019 370.9 2.5e-101
XP_016866538 (OMIM: 610322) PREDICTED: transcripti (1200) 4019 370.9 2.5e-101
XP_016866539 (OMIM: 610322) PREDICTED: transcripti (1193) 3882 358.8 1.1e-97
XP_016866535 (OMIM: 610322) PREDICTED: transcripti (1232) 3882 358.8 1.2e-97
XP_016866534 (OMIM: 610322) PREDICTED: transcripti (1254) 3882 358.8 1.2e-97
XP_016866533 (OMIM: 610322) PREDICTED: transcripti (1262) 3882 358.8 1.2e-97
XP_016866530 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866529 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866525 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866532 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_011513045 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_011513043 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866531 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866524 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_011513044 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_011513046 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_011513047 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866528 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866527 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866526 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866523 (OMIM: 610322) PREDICTED: transcripti (1274) 3882 358.8 1.2e-97
XP_016866536 (OMIM: 610322) PREDICTED: transcripti (1228) 3868 357.6 2.7e-97
XP_016866544 (OMIM: 610322) PREDICTED: transcripti ( 795) 1823 176.4 6e-43
XP_016884309 (OMIM: 607372) PREDICTED: mediator of ( 667) 337 44.8 0.0021
NP_001280166 (OMIM: 607372) mediator of RNA polyme ( 722) 337 44.8 0.0022
NP_001280164 (OMIM: 607372) mediator of RNA polyme ( 722) 337 44.8 0.0022
NP_056973 (OMIM: 607372) mediator of RNA polymeras ( 748) 337 44.8 0.0023
NP_001280165 (OMIM: 607372) mediator of RNA polyme ( 677) 330 44.2 0.0032
XP_011514285 (OMIM: 104300,608254) PREDICTED: PAX- (1022) 326 44.0 0.0056
XP_016867370 (OMIM: 104300,608254) PREDICTED: PAX- (1035) 326 44.0 0.0056
XP_005249596 (OMIM: 104300,608254) PREDICTED: PAX- (1035) 326 44.0 0.0056
XP_011514284 (OMIM: 104300,608254) PREDICTED: PAX- (1043) 326 44.0 0.0056
NP_031375 (OMIM: 104300,608254) PAX-interacting pr (1069) 326 44.0 0.0057
XP_016883239 (OMIM: 605299) PREDICTED: nuclear rec (1094) 320 43.5 0.0084
NP_001280163 (OMIM: 607372) mediator of RNA polyme ( 731) 313 42.7 0.0097
>>XP_016866543 (OMIM: 610322) PREDICTED: transcriptional (1117 aa)
initn: 7721 init1: 7721 opt: 7721 Z-score: 3711.2 bits: 698.5 E(85289): 5.6e-200
Smith-Waterman score: 7721; 100.0% identity (100.0% similar) in 1117 aa overlap (1-1117:1-1117)
10 20 30 40 50 60
pF1KB3 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 PNLKQEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLKQEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 QSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 THKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 EMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 CVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 PKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTNQV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 TKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 HMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILD
1030 1040 1050 1060 1070 1080
1090 1100 1110
pF1KB3 DDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::::::::::::::::::::::::::::::
XP_016 DDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1090 1100 1110
>>XP_016866541 (OMIM: 610322) PREDICTED: transcriptional (1129 aa)
initn: 6553 init1: 6553 opt: 6558 Z-score: 3154.9 bits: 595.6 E(85289): 5.5e-169
Smith-Waterman score: 7687; 98.9% identity (98.9% similar) in 1129 aa overlap (1-1117:1-1129)
10 20 30 40 50 60
pF1KB3 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 PNLKQEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLKQEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 QSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 THKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 EMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 CVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEV
850 860 870 880 890 900
910 920 930 940
pF1KB3 PKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGA------------VFSSRQALN
::::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 PKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGADCRCHVTPFLPQVFSSRQALN
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB3 GHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKEC
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB3 GKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLS
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110
pF1KB3 LIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1090 1100 1110 1120
>>XP_016866542 (OMIM: 610322) PREDICTED: transcriptional (1129 aa)
initn: 6553 init1: 6553 opt: 6558 Z-score: 3154.9 bits: 595.6 E(85289): 5.5e-169
Smith-Waterman score: 7687; 98.9% identity (98.9% similar) in 1129 aa overlap (1-1117:1-1129)
10 20 30 40 50 60
pF1KB3 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 PNLKQEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLKQEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 QSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 THKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 EMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 CVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEV
850 860 870 880 890 900
910 920 930 940
pF1KB3 PKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGA------------VFSSRQALN
::::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 PKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGADCRCHVTPFLPQVFSSRQALN
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KB3 GHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKEC
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KB3 GKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLS
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110
pF1KB3 LIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1090 1100 1110 1120
>>XP_016866540 (OMIM: 610322) PREDICTED: transcriptional (1171 aa)
initn: 6782 init1: 5625 opt: 5625 Z-score: 2708.4 bits: 513.0 E(85289): 4.1e-144
Smith-Waterman score: 7457; 95.3% identity (95.3% similar) in 1149 aa overlap (1-1095:1-1149)
10 20 30 40 50 60
pF1KB3 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 PNLKQEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLKQEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 QSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 PLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 THKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVAL
730 740 750 760 770 780
790 800
pF1KB3 EMLLLRKPVRLKCHPLANYHYA--------------------------------------
::::::::::::::::::::::
XP_016 EMLLLRKPVRLKCHPLANYHYADGPGSYITSGVASGKQFGNMKGHASQKSTGLGTEHCFW
790 800 810 820 830 840
810 820 830 840 850
pF1KB3 ----GSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQKSGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKH
850 860 870 880 890 900
860 870 880 890 900 910
pF1KB3 RTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGP
910 920 930 940 950 960
920 930 940 950 960
pF1KB3 PLQALGQPSGSFICEMPNCGA------------VFSSRQALNGHARIHGGTNQVTKARGA
::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 PLQALGQPSGSFICEMPNCGADCRCHVTPFLPQVFSSRQALNGHARIHGGTNQVTKARGA
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KB3 IPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTHR
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KB3 QQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILDDDVVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILDDDVVQQ
1090 1100 1110 1120 1130 1140
1090 1100 1110
pF1KB3 LGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::
XP_016 LGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1150 1160 1170
>>NP_001284502 (OMIM: 610322) transcriptional-regulating (1220 aa)
initn: 3924 init1: 3885 opt: 4043 Z-score: 1951.4 bits: 373.0 E(85289): 5.9e-102
Smith-Waterman score: 7000; 91.0% identity (91.0% similar) in 1149 aa overlap (72-1117:72-1220)
50 60 70 80 90 100
pF1KB3 GGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNL
::::::::::::::::::::::::::::::
NP_001 GGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNL
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB3 ANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNN
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB3 MAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPAL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB3 QVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQ
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB3 RISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQ
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB3 QQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQ
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB3 REDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHL
410 420 430 440 450 460
470 480 490 500 510 520
pF1KB3 NNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEF
470 480 490 500 510 520
530 540
pF1KB3 KNLPALNGHMRSHGGMRASPNLKQE-----------------------------------
:::::::::::::::::::::::::
NP_001 KNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTP
530 540 550 560 570 580
pF1KB3 ------------------------------------------------------------
NP_001 MVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLVRMTLSPPHSPQG
590 600 610 620 630 640
550 560 570 580 590
pF1KB3 --------IPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPRTPAEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT
650 660 670 680 690 700
600 610 620 630 640 650
pF1KB3 LYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLP
710 720 730 740 750 760
660 670 680 690 700 710
pF1KB3 LTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALA
770 780 790 800 810 820
720 730 740 750 760 770
pF1KB3 QDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMV
830 840 850 860 870 880
780 790 800 810 820 830
pF1KB3 ALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTV
890 900 910 920 930 940
840 850 860 870 880 890
pF1KB3 AQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEES
950 960 970 980 990 1000
900 910 920 930 940 950
pF1KB3 EVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTN
1010 1020 1030 1040 1050 1060
960 970 980 990 1000 1010
pF1KB3 QVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSR
1070 1080 1090 1100 1110 1120
1020 1030 1040 1050 1060 1070
pF1KB3 NAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDI
1130 1140 1150 1160 1170 1180
1080 1090 1100 1110
pF1KB3 LDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::::::::::::::::::::::::::::::::
NP_001 LDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1190 1200 1210 1220
>--
initn: 505 init1: 505 opt: 505 Z-score: 259.1 bits: 59.9 E(85289): 1.1e-07
Smith-Waterman score: 505; 100.0% identity (100.0% similar) in 71 aa overlap (1-71:1-71)
10 20 30 40 50 60
pF1KB3 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
:::::::::::
NP_001 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
70 80 90 100 110 120
>>XP_016866537 (OMIM: 610322) PREDICTED: transcriptional (1220 aa)
initn: 3924 init1: 3885 opt: 4043 Z-score: 1951.4 bits: 373.0 E(85289): 5.9e-102
Smith-Waterman score: 7000; 91.0% identity (91.0% similar) in 1149 aa overlap (72-1117:72-1220)
50 60 70 80 90 100
pF1KB3 GGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNL
::::::::::::::::::::::::::::::
XP_016 GGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNL
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB3 ANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNN
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB3 MAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPAL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB3 QVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQ
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB3 RISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQ
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB3 QQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQ
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB3 REDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHL
410 420 430 440 450 460
470 480 490 500 510 520
pF1KB3 NNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEF
470 480 490 500 510 520
530 540
pF1KB3 KNLPALNGHMRSHGGMRASPNLKQE-----------------------------------
:::::::::::::::::::::::::
XP_016 KNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTP
530 540 550 560 570 580
pF1KB3 ------------------------------------------------------------
XP_016 MVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLVRMTLSPPHSPQG
590 600 610 620 630 640
550 560 570 580 590
pF1KB3 --------IPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAPRTPAEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT
650 660 670 680 690 700
600 610 620 630 640 650
pF1KB3 LYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLP
710 720 730 740 750 760
660 670 680 690 700 710
pF1KB3 LTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALA
770 780 790 800 810 820
720 730 740 750 760 770
pF1KB3 QDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMV
830 840 850 860 870 880
780 790 800 810 820 830
pF1KB3 ALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTV
890 900 910 920 930 940
840 850 860 870 880 890
pF1KB3 AQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEES
950 960 970 980 990 1000
900 910 920 930 940 950
pF1KB3 EVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTN
1010 1020 1030 1040 1050 1060
960 970 980 990 1000 1010
pF1KB3 QVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSR
1070 1080 1090 1100 1110 1120
1020 1030 1040 1050 1060 1070
pF1KB3 NAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDI
1130 1140 1150 1160 1170 1180
1080 1090 1100 1110
pF1KB3 LDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::::::::::::::::::::::::::::::::
XP_016 LDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1190 1200 1210 1220
>--
initn: 505 init1: 505 opt: 505 Z-score: 259.1 bits: 59.9 E(85289): 1.1e-07
Smith-Waterman score: 505; 100.0% identity (100.0% similar) in 71 aa overlap (1-71:1-71)
10 20 30 40 50 60
pF1KB3 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
:::::::::::
XP_016 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
70 80 90 100 110 120
>>NP_277037 (OMIM: 610322) transcriptional-regulating fa (1200 aa)
initn: 3941 init1: 3873 opt: 4019 Z-score: 1940.1 bits: 370.9 E(85289): 2.5e-101
Smith-Waterman score: 7187; 92.8% identity (92.8% similar) in 1149 aa overlap (52-1117:52-1200)
30 40 50 60 70 80
pF1KB3 QQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSR
::::::::::::::::::::::::::::::
NP_277 QQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSR
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB3 QGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 QGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLH
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB3 KLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 KLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRY
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB3 QQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 QQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHM
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB3 QQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 QQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSM
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB3 QIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 QIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQE
330 340 350 360 370 380
390 400 410 420 430 440
pF1KB3 PQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 PQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDL
390 400 410 420 430 440
450 460 470 480 490 500
pF1KB3 TRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 TRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGA
450 460 470 480 490 500
510 520 530 540
pF1KB3 FGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQE---------------
:::::::::::::::::::::::::::::::::::::::::::::
NP_277 FGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLP
510 520 530 540 550 560
pF1KB3 ------------------------------------------------------------
NP_277 PPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMS
570 580 590 600 610 620
550 560 570 580 590
pF1KB3 --------IPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 DDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT
630 640 650 660 670 680
600 610 620 630 640 650
pF1KB3 LYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 LYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLP
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB3 LTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 LTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALA
750 760 770 780 790 800
720 730 740 750 760 770
pF1KB3 QDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 QDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMV
810 820 830 840 850 860
780 790 800 810 820 830
pF1KB3 ALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 ALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTV
870 880 890 900 910 920
840 850 860 870 880 890
pF1KB3 AQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 AQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEES
930 940 950 960 970 980
900 910 920 930 940 950
pF1KB3 EVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 EVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTN
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KB3 QVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 QVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSR
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KB3 NAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 NAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDI
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110
pF1KB3 LDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::::::::::::::::::::::::::::::::
NP_277 LDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1170 1180 1190 1200
>>XP_016866538 (OMIM: 610322) PREDICTED: transcriptional (1200 aa)
initn: 3941 init1: 3873 opt: 4019 Z-score: 1940.1 bits: 370.9 E(85289): 2.5e-101
Smith-Waterman score: 7187; 92.8% identity (92.8% similar) in 1149 aa overlap (52-1117:52-1200)
30 40 50 60 70 80
pF1KB3 QQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSR
::::::::::::::::::::::::::::::
XP_016 QQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSR
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB3 QGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLH
90 100 110 120 130 140
150 160 170 180 190 200
pF1KB3 KLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRY
150 160 170 180 190 200
210 220 230 240 250 260
pF1KB3 QQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHM
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB3 QQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSM
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB3 QIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQE
330 340 350 360 370 380
390 400 410 420 430 440
pF1KB3 PQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDL
390 400 410 420 430 440
450 460 470 480 490 500
pF1KB3 TRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGA
450 460 470 480 490 500
510 520 530 540
pF1KB3 FGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQE---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLP
510 520 530 540 550 560
pF1KB3 ------------------------------------------------------------
XP_016 PPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMS
570 580 590 600 610 620
550 560 570 580 590
pF1KB3 --------IPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGAT
630 640 650 660 670 680
600 610 620 630 640 650
pF1KB3 LYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLP
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB3 LTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALA
750 760 770 780 790 800
720 730 740 750 760 770
pF1KB3 QDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMV
810 820 830 840 850 860
780 790 800 810 820 830
pF1KB3 ALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTV
870 880 890 900 910 920
840 850 860 870 880 890
pF1KB3 AQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEES
930 940 950 960 970 980
900 910 920 930 940 950
pF1KB3 EVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTN
990 1000 1010 1020 1030 1040
960 970 980 990 1000 1010
pF1KB3 QVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSR
1050 1060 1070 1080 1090 1100
1020 1030 1040 1050 1060 1070
pF1KB3 NAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDI
1110 1120 1130 1140 1150 1160
1080 1090 1100 1110
pF1KB3 LDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::::::::::::::::::::::::::::::::
XP_016 LDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1170 1180 1190 1200
>>XP_016866539 (OMIM: 610322) PREDICTED: transcriptional (1193 aa)
initn: 5034 init1: 3871 opt: 3882 Z-score: 1874.6 bits: 358.8 E(85289): 1.1e-97
Smith-Waterman score: 6511; 82.4% identity (82.4% similar) in 1218 aa overlap (1-1073:1-1149)
10 20 30 40 50 60
pF1KB3 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
490 500 510 520 530 540
pF1KB3 PNLKQE------------------------------------------------------
::::::
XP_016 PNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQ
550 560 570 580 590 600
550
pF1KB3 -------------------------------------------------IPRKHQPSVPK
:::::::::::
XP_016 GFTNSTVAAPSARDKPASSMSDDEMPVLVRMTLSPPHSPQGAAPRTPAEIPRKHQPSVPK
610 620 630 640 650 660
560 570 580 590 600 610
pF1KB3 AEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLD
670 680 690 700 710 720
620 630 640 650 660 670
pF1KB3 PTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSID
730 740 750 760 770 780
680 690 700 710 720 730
pF1KB3 GSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENH
790 800 810 820 830 840
740 750 760 770 780 790
pF1KB3 DLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLA
850 860 870 880 890 900
800 810
pF1KB3 NYHYA------------------------------------------GSDKWTSLERKLF
::::: :::::::::::::
XP_016 NYHYADGPGSYITSGVASGKQFGNMKGHASQKSTGLGTEHCFWGQKSGSDKWTSLERKLF
910 920 930 940 950 960
820 830 840 850 860 870
pF1KB3 NKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCV-----
970 980 990 1000 1010
880 890 900 910 920 930
pF1KB3 EELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMP
XP_016 ------------------------------------------------------------
940 950 960 970 980 990
pF1KB3 NCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----VFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSG
1020 1030 1040 1050 1060 1070
1000 1010 1020 1030 1040 1050
pF1KB3 ETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGP
1080 1090 1100 1110 1120 1130
1060 1070 1080 1090 1100 1110
pF1KB3 VGAPGLLPLDQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDA
::::::::::::::::::
XP_016 VGAPGLLPLDQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDA
1140 1150 1160 1170 1180 1190
>>XP_016866535 (OMIM: 610322) PREDICTED: transcriptional (1232 aa)
initn: 5011 init1: 3854 opt: 3882 Z-score: 1874.4 bits: 358.8 E(85289): 1.2e-97
Smith-Waterman score: 6951; 90.0% identity (90.0% similar) in 1149 aa overlap (1-1034:1-1149)
10 20 30 40 50 60
pF1KB3 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRAS
490 500 510 520 530 540
pF1KB3 PNLKQE------------------------------------------------------
::::::
XP_016 PNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQ
550 560 570 580 590 600
550
pF1KB3 -------------------------------------------------IPRKHQPSVPK
:::::::::::
XP_016 GFTNSTVAAPSARDKPASSMSDDEMPVLVRMTLSPPHSPQGAAPRTPAEIPRKHQPSVPK
610 620 630 640 650 660
560 570 580 590 600 610
pF1KB3 AEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLD
670 680 690 700 710 720
620 630 640 650 660 670
pF1KB3 PTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSID
730 740 750 760 770 780
680 690 700 710 720 730
pF1KB3 GSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENH
790 800 810 820 830 840
740 750 760 770 780 790
pF1KB3 DLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLA
850 860 870 880 890 900
800 810 820 830 840 850
pF1KB3 NYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRK
910 920 930 940 950 960
860 870 880 890 900 910
pF1KB3 HRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEG
970 980 990 1000 1010 1020
920 930 940 950 960
pF1KB3 PPLQALGQPSGSFICEMPNCGA------------VFSSRQALNGHARIHGGTNQVTKARG
:::::::::::::::::::::: ::::::::::::::::::::::::::
XP_016 PPLQALGQPSGSFICEMPNCGADCRCHVTPFLPQVFSSRQALNGHARIHGGTNQVTKARG
1030 1040 1050 1060 1070 1080
970 980 990 1000 1010 1020
pF1KB3 AIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTH
1090 1100 1110 1120 1130 1140
1030 1040 1050 1060 1070 1080
pF1KB3 RQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILDDDVVQ
:::::::::
XP_016 RQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILDDDVVQ
1150 1160 1170 1180 1190 1200
>--
initn: 520 init1: 520 opt: 520 Z-score: 266.3 bits: 61.2 E(85289): 4.3e-08
Smith-Waterman score: 520; 100.0% identity (100.0% similar) in 83 aa overlap (1035-1117:1150-1232)
1010 1020 1030 1040 1050 1060
pF1KB3 CKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPL
::::::::::::::::::::::::::::::
XP_016 CKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPL
1120 1130 1140 1150 1160 1170
1070 1080 1090 1100 1110
pF1KB3 DQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL
1180 1190 1200 1210 1220 1230
1117 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:18:01 2016 done: Thu Nov 3 13:18:03 2016
Total Scan time: 15.250 Total Display time: 0.520
Function used was FASTA [36.3.4 Apr, 2011]