Result of FASTA (omim) for
pF1KB3449
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3449, 199 aa
1>>>pF1KB3449 199 - 199 aa - 199 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0045+/-0.000342; mu= 14.6094+/- 0.021
mean_var=54.9761+/-10.982, 0's: 0 Z-trim(114.5): 14 B-trim: 700 in 2/50
Lambda= 0.172977
statistics sampled from 24432 (24446) to 24432 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.682), E-opt: 0.2 (0.287), width: 16
Scan time: 5.310
The best scores are: opt bits E(85289)
NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo ( 199) 1362 347.5 8.1e-96
NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 1362 347.5 8.1e-96
NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 1362 347.5 8.1e-96
NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sap ( 199) 1362 347.5 8.1e-96
NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sap ( 198) 1101 282.4 3.3e-76
NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor ( 271) 951 245.0 7.9e-65
XP_005274495 (OMIM: 300927) PREDICTED: peroxiredox ( 257) 944 243.3 2.5e-64
XP_016884719 (OMIM: 300927) PREDICTED: peroxiredox ( 350) 921 237.6 1.8e-62
XP_016884720 (OMIM: 300927) PREDICTED: peroxiredox ( 336) 914 235.8 5.8e-62
NP_006784 (OMIM: 604769) thioredoxin-dependent per ( 256) 876 226.3 3.3e-59
NP_001289201 (OMIM: 604769) thioredoxin-dependent ( 198) 545 143.7 1.9e-34
NP_004896 (OMIM: 602316) peroxiredoxin-6 [Homo sap ( 224) 199 57.3 2.1e-08
NP_036226 (OMIM: 606583) peroxiredoxin-5, mitochon ( 214) 132 40.6 0.0022
>>NP_001189360 (OMIM: 176763) peroxiredoxin-1 [Homo sapi (199 aa)
initn: 1362 init1: 1362 opt: 1362 Z-score: 1841.2 bits: 347.5 E(85289): 8.1e-96
Smith-Waterman score: 1362; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
130 140 150 160 170 180
190
pF1KB3 SDTIKPDVQKSKEYFSKQK
:::::::::::::::::::
NP_001 SDTIKPDVQKSKEYFSKQK
190
>>NP_859047 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 1362 init1: 1362 opt: 1362 Z-score: 1841.2 bits: 347.5 E(85289): 8.1e-96
Smith-Waterman score: 1362; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
130 140 150 160 170 180
190
pF1KB3 SDTIKPDVQKSKEYFSKQK
:::::::::::::::::::
NP_859 SDTIKPDVQKSKEYFSKQK
190
>>NP_002565 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 1362 init1: 1362 opt: 1362 Z-score: 1841.2 bits: 347.5 E(85289): 8.1e-96
Smith-Waterman score: 1362; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
130 140 150 160 170 180
190
pF1KB3 SDTIKPDVQKSKEYFSKQK
:::::::::::::::::::
NP_002 SDTIKPDVQKSKEYFSKQK
190
>>NP_859048 (OMIM: 176763) peroxiredoxin-1 [Homo sapiens (199 aa)
initn: 1362 init1: 1362 opt: 1362 Z-score: 1841.2 bits: 347.5 E(85289): 8.1e-96
Smith-Waterman score: 1362; 100.0% identity (100.0% similar) in 199 aa overlap (1-199:1-199)
10 20 30 40 50 60
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
130 140 150 160 170 180
190
pF1KB3 SDTIKPDVQKSKEYFSKQK
:::::::::::::::::::
NP_859 SDTIKPDVQKSKEYFSKQK
190
>>NP_005800 (OMIM: 600538) peroxiredoxin-2 [Homo sapiens (198 aa)
initn: 1099 init1: 1002 opt: 1101 Z-score: 1489.3 bits: 282.4 E(85289): 3.3e-76
Smith-Waterman score: 1101; 77.8% identity (96.0% similar) in 198 aa overlap (1-198:1-197)
10 20 30 40 50 60
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
:.::::.::.:::.::::::. :: ::...::::::::::.:::::::::::::::::::
NP_005 MASGNARIGKPAPDFKATAVV-DGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFS
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
.:::.:.::.:.:.:.::::.: ::::.:::.:.:::::.::::..: : ...::::::
NP_005 NRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
.::::..::::::: ::.:::::::::::::::::.::::::::.::.::::::::::::
NP_005 TDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPG
120 130 140 150 160 170
190
pF1KB3 SDTIKPDVQKSKEYFSKQK
::::::.:. :::::::.
NP_005 SDTIKPNVDDSKEYFSKHN
180 190
>>NP_006397 (OMIM: 300927) peroxiredoxin-4 precursor [Ho (271 aa)
initn: 966 init1: 905 opt: 951 Z-score: 1284.8 bits: 245.0 E(85289): 7.9e-65
Smith-Waterman score: 951; 70.3% identity (89.6% similar) in 192 aa overlap (6-197:79-269)
10 20 30
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYK
:::..::: ...:::. ::.::...:.::.
NP_006 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVI-DGEFKELKLTDYR
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB3 GKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQG
:::.::::::::::::::::::::.:: :::...: .:.. ::::.: ::::.:::..::
NP_006 GKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQG
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB3 GLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDE
::::. :::.:: . :..:::: : : ..::::::::::::::::.:::::::::::
NP_006 GLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDE
170 180 190 200 210 220
160 170 180 190
pF1KB3 TLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
:::::::::.::::::::::::::::.:: :: . .::.:
NP_006 TLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
230 240 250 260 270
>>XP_005274495 (OMIM: 300927) PREDICTED: peroxiredoxin-4 (257 aa)
initn: 959 init1: 905 opt: 944 Z-score: 1275.8 bits: 243.3 E(85289): 2.5e-64
Smith-Waterman score: 944; 68.9% identity (89.1% similar) in 193 aa overlap (5-197:64-255)
10 20 30
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDY
:. ...::: ...:::. ::.::...:.::
XP_005 EAREGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVI-DGEFKELKLTDY
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB3 KGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQ
.:::.::::::::::::::::::::.:: :::...: .:.. ::::.: ::::.:::..:
XP_005 RGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQ
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB3 GGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVD
:::::. :::.:: . :..:::: : : ..::::::::::::::::.::::::::::
XP_005 GGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVD
160 170 180 190 200 210
160 170 180 190
pF1KB3 ETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
::::::::::.::::::::::::::::.:: :: . .::.:
XP_005 ETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
220 230 240 250
>>XP_016884719 (OMIM: 300927) PREDICTED: peroxiredoxin-4 (350 aa)
initn: 936 init1: 875 opt: 921 Z-score: 1242.6 bits: 237.6 E(85289): 1.8e-62
Smith-Waterman score: 921; 72.1% identity (91.6% similar) in 179 aa overlap (6-184:79-256)
10 20 30
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYK
:::..::: ...:::. ::.::...:.::.
XP_016 EECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVI-DGEFKELKLTDYR
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB3 GKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQG
:::.::::::::::::::::::::.:: :::...: .:.. ::::.: ::::.:::..::
XP_016 GKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQG
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB3 GLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDE
::::. :::.:: . :..:::: : : ..::::::::::::::::.:::::::::::
XP_016 GLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVDE
170 180 190 200 210 220
160 170 180 190
pF1KB3 TLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
:::::::::.::::::::::::::::.:.
XP_016 TLRLVQAFQYTDKHGEVCPAGWKPGSETVSIYICFYVELMVRVEKNAGRAQWLTPVIPAL
230 240 250 260 270 280
>>XP_016884720 (OMIM: 300927) PREDICTED: peroxiredoxin-4 (336 aa)
initn: 929 init1: 875 opt: 914 Z-score: 1233.5 bits: 235.8 E(85289): 5.8e-62
Smith-Waterman score: 914; 70.6% identity (91.1% similar) in 180 aa overlap (5-184:64-242)
10 20 30
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDY
:. ...::: ...:::. ::.::...:.::
XP_016 EAREGEDWEREPPRQRPPIYEPPESEELPDNVMVSKPAPYWEGTAVI-DGEFKELKLTDY
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB3 KGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQ
.:::.::::::::::::::::::::.:: :::...: .:.. ::::.: ::::.:::..:
XP_016 RGKYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINTEVVACSVDSQFTHLAWINTPRRQ
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB3 GGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVD
:::::. :::.:: . :..:::: : : ..::::::::::::::::.::::::::::
XP_016 GGLGPIRIPLLSDLTHQISKDYGVYLEDSGHTLRGLFIIDDKGILRQITLNDLPVGRSVD
160 170 180 190 200 210
160 170 180 190
pF1KB3 ETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
::::::::::.::::::::::::::::.:.
XP_016 ETLRLVQAFQYTDKHGEVCPAGWKPGSETVSIYICFYVELMVRVEKNAGRAQWLTPVIPA
220 230 240 250 260 270
>>NP_006784 (OMIM: 604769) thioredoxin-dependent peroxid (256 aa)
initn: 862 init1: 832 opt: 876 Z-score: 1184.1 bits: 226.3 E(85289): 3.3e-59
Smith-Waterman score: 876; 64.2% identity (87.9% similar) in 190 aa overlap (8-197:65-253)
10 20 30
pF1KB3 MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGK
. . :: ::.:::. .:.:::.::.:.:::
NP_006 CGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVV-NGEFKDLSLDDFKGK
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB3 YVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGL
:.:.:::::::::::::::.::::.:.::. .::.:...:::::: ::::.:::.:.:::
NP_006 YLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGL
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB3 GPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETL
: ::: :.:: . :..::::: :...::::::: .:......::::::::::.:::
NP_006 GHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETL
160 170 180 190 200 210
160 170 180 190
pF1KB3 RLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
:::.:::... :::::::.: : : ::::. :::::.:
NP_006 RLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ
220 230 240 250
199 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:27:43 2016 done: Fri Nov 4 02:27:44 2016
Total Scan time: 5.310 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]