Result of FASTA (omim) for
pF1KB3282
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3282, 740 aa
1>>>pF1KB3282 740 - 740 aa - 740 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8086+/-0.000488; mu= 17.3978+/- 0.030
mean_var=86.5378+/-17.130, 0's: 0 Z-trim(109.1): 208 B-trim: 92 in 1/54
Lambda= 0.137870
statistics sampled from 16977 (17212) to 16977 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.537), E-opt: 0.2 (0.202), width: 16
Scan time: 10.110
The best scores are: opt bits E(85289)
XP_011536329 (OMIM: 601081) PREDICTED: ATP-binding ( 740) 4839 973.6 0
NP_005155 (OMIM: 601081) ATP-binding cassette sub- ( 740) 4839 973.6 0
XP_016874481 (OMIM: 601081) PREDICTED: ATP-binding ( 674) 4376 881.5 0
XP_016874482 (OMIM: 601081) PREDICTED: ATP-binding ( 556) 3542 715.6 1.4e-205
XP_016874483 (OMIM: 601081) PREDICTED: ATP-binding ( 375) 2393 486.9 6.4e-137
NP_000024 (OMIM: 300100,300371) ATP-binding casset ( 745) 1826 374.3 9.8e-103
XP_016857441 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 1041 218.1 8.2e-56
XP_016857442 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 1041 218.1 8.2e-56
XP_016857443 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 1041 218.1 8.2e-56
NP_002849 (OMIM: 170995,616278) ATP-binding casset ( 659) 1041 218.1 9e-56
XP_006710865 (OMIM: 170995,616278) PREDICTED: ATP- ( 683) 1041 218.1 9.2e-56
XP_011540179 (OMIM: 170995,616278) PREDICTED: ATP- ( 347) 1037 217.2 9.3e-56
XP_016877031 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 524 115.1 4.8e-25
XP_016877029 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 524 115.1 4.8e-25
XP_016877024 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 524 115.1 4.8e-25
XP_016877025 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 524 115.1 4.8e-25
XP_016877028 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 524 115.1 4.8e-25
XP_016877026 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 524 115.1 4.8e-25
XP_016877030 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 524 115.1 4.8e-25
XP_016877027 (OMIM: 603214,614857) PREDICTED: ATP- ( 343) 524 115.1 4.8e-25
XP_016877023 (OMIM: 603214,614857) PREDICTED: ATP- ( 402) 524 115.2 5.5e-25
XP_005268006 (OMIM: 603214,614857) PREDICTED: ATP- ( 447) 524 115.2 5.9e-25
XP_005268003 (OMIM: 603214,614857) PREDICTED: ATP- ( 447) 524 115.2 5.9e-25
XP_005267997 (OMIM: 603214,614857) PREDICTED: ATP- ( 468) 524 115.2 6.2e-25
XP_005267999 (OMIM: 603214,614857) PREDICTED: ATP- ( 468) 524 115.2 6.2e-25
XP_005267998 (OMIM: 603214,614857) PREDICTED: ATP- ( 468) 524 115.2 6.2e-25
XP_005267996 (OMIM: 603214,614857) PREDICTED: ATP- ( 468) 524 115.2 6.2e-25
XP_011535343 (OMIM: 603214,614857) PREDICTED: ATP- ( 515) 524 115.2 6.7e-25
XP_006720286 (OMIM: 603214,614857) PREDICTED: ATP- ( 519) 524 115.2 6.7e-25
XP_016877021 (OMIM: 603214,614857) PREDICTED: ATP- ( 564) 524 115.3 7.2e-25
NP_005041 (OMIM: 603214,614857) ATP-binding casset ( 606) 524 115.3 7.6e-25
XP_016877032 (OMIM: 603214,614857) PREDICTED: ATP- ( 329) 479 106.2 2.3e-22
XP_016877022 (OMIM: 603214,614857) PREDICTED: ATP- ( 550) 479 106.3 3.5e-22
NP_001116146 (OMIM: 170995,616278) ATP-binding cas ( 236) 402 90.7 7.2e-18
XP_016877033 (OMIM: 603214,614857) PREDICTED: ATP- ( 309) 257 62.0 4.3e-09
XP_016877020 (OMIM: 603214,614857) PREDICTED: ATP- ( 572) 257 62.2 7e-09
XP_016874593 (OMIM: 605453) PREDICTED: ATP-binding ( 485) 239 58.5 7.4e-08
NP_001229942 (OMIM: 605453) ATP-binding cassette s ( 703) 239 58.6 9.9e-08
XP_011536400 (OMIM: 605453) PREDICTED: ATP-binding ( 548) 227 56.2 4.2e-07
XP_005253615 (OMIM: 605453) PREDICTED: ATP-binding ( 548) 227 56.2 4.2e-07
NP_062570 (OMIM: 605453) ATP-binding cassette sub- ( 723) 227 56.3 5.3e-07
XP_011536398 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 227 56.3 5.6e-07
XP_016874592 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 227 56.3 5.6e-07
NP_062571 (OMIM: 605453) ATP-binding cassette sub- ( 766) 227 56.3 5.6e-07
XP_011536397 (OMIM: 605453) PREDICTED: ATP-binding ( 766) 227 56.3 5.6e-07
NP_001288759 (OMIM: 605250) multidrug resistance-a ( 784) 227 56.3 5.7e-07
XP_016875811 (OMIM: 605250) PREDICTED: multidrug r ( 816) 227 56.3 5.8e-07
XP_016875809 (OMIM: 605250) PREDICTED: multidrug r ( 830) 227 56.3 5.9e-07
NP_001098985 (OMIM: 605250) multidrug resistance-a ( 859) 227 56.3 6.1e-07
NP_001288758 (OMIM: 605250) multidrug resistance-a (1278) 227 56.4 8.4e-07
>>XP_011536329 (OMIM: 601081) PREDICTED: ATP-binding cas (740 aa)
initn: 4839 init1: 4839 opt: 4839 Z-score: 5204.3 bits: 973.6 E(85289): 0
Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 740 aa overlap (1-740:1-740)
10 20 30 40 50 60
pF1KB3 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIIC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 AVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNEL
670 680 690 700 710 720
730 740
pF1KB3 CKILGEDSVLKTIKNEDETS
::::::::::::::::::::
XP_011 CKILGEDSVLKTIKNEDETS
730 740
>>NP_005155 (OMIM: 601081) ATP-binding cassette sub-fami (740 aa)
initn: 4839 init1: 4839 opt: 4839 Z-score: 5204.3 bits: 973.6 E(85289): 0
Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 740 aa overlap (1-740:1-740)
10 20 30 40 50 60
pF1KB3 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIIC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 AVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNEL
670 680 690 700 710 720
730 740
pF1KB3 CKILGEDSVLKTIKNEDETS
::::::::::::::::::::
NP_005 CKILGEDSVLKTIKNEDETS
730 740
>>XP_016874481 (OMIM: 601081) PREDICTED: ATP-binding cas (674 aa)
initn: 4407 init1: 4376 opt: 4376 Z-score: 4707.2 bits: 881.5 E(85289): 0
Smith-Waterman score: 4376; 99.7% identity (99.7% similar) in 671 aa overlap (1-671:1-671)
10 20 30 40 50 60
pF1KB3 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIIC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 AVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 ITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNEL
:::::::: :
XP_016 ITHRPSLWYSHNTC
670
>>XP_016874482 (OMIM: 601081) PREDICTED: ATP-binding cas (556 aa)
initn: 3542 init1: 3542 opt: 3542 Z-score: 3811.9 bits: 715.6 E(85289): 1.4e-205
Smith-Waterman score: 3542; 100.0% identity (100.0% similar) in 548 aa overlap (1-548:1-548)
10 20 30 40 50 60
pF1KB3 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIIC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWD
::::::::
XP_016 QHMFYIPQSLSVFPSP
550
>>XP_016874483 (OMIM: 601081) PREDICTED: ATP-binding cas (375 aa)
initn: 2393 init1: 2393 opt: 2393 Z-score: 2579.2 bits: 486.9 E(85289): 6.4e-137
Smith-Waterman score: 2393; 100.0% identity (100.0% similar) in 373 aa overlap (1-373:1-373)
10 20 30 40 50 60
pF1KB3 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSGHGKKKAAAYPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRII
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 AIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYT
:::::::::::::
XP_016 AIPIITATGFADGGH
370
>>NP_000024 (OMIM: 300100,300371) ATP-binding cassette s (745 aa)
initn: 3099 init1: 1816 opt: 1826 Z-score: 1965.4 bits: 374.3 E(85289): 9.8e-103
Smith-Waterman score: 3151; 65.7% identity (86.0% similar) in 727 aa overlap (14-726:10-722)
10 20 30 40 50
pF1KB3 MTHMLNAAADRVKWTRSSAAKRAACLVA-AAYALKTLYPIIGKRLKQSGHGKKKAAAYPA
: :... ::.: :.: :::. . .::.. . : . .: . :. :.
NP_000 MPVLSRPRPW-RGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPA-RGLQAPAGEPT
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 AENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTF
: . . . :.: :...:: : ..:::... ::: : :::.::.::::
NP_000 QEASGV--------AAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTF
60 70 80 90 100
120 130 140 150 160 170
pF1KB3 LSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRL
::.::: :::.... ::.: ::.: .:..::.::.::::::::::::: .:::.::.::
NP_000 LSVYVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB3 VDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTS
: :::. ::..::::.: :::::: :::::::::.. :. ::::::::::::.::: .::
NP_000 VAHAYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB3 YTLIQTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRI
:::...: ::::. :. .:::::. ::.::.: :::::.::::::.::: :::.:::.
NP_000 YTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRV
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB3 IANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIM
.:: :::::: ::.::. ::.::. ::.:.:::: .::::.:.::::::::::.:::.:
NP_000 VANSEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLM
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB3 VAIPIITATGFADGE---------DGQKQVMVSERTEAFTTARNLLASGADAIERIMSSY
::.:::::::..... . ... .::::::::: :::::...:::::::::::
NP_000 VAVPIITATGYSESDAEAVKKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSY
350 360 370 380 390 400
420 430 440 450 460
pF1KB3 KEVTELAGYTARVYNMFWVFDEVKRGIYKRTAVIQESESHS----KNGAKVELPLSDTLA
:::::::::::::..:: ::..:.: .:: ...... : ..:..:: ::.
NP_000 KEVTELAGYTARVHEMFQVFEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLK----
410 420 430 440 450 460
470 480 490 500 510 520
pF1KB3 IKGKVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSG
:.:.:.::..::::::.::.::.::::.. ::..::::::::::::::::::::::::.:
NP_000 IRGQVVDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGG
470 480 490 500 510 520
530 540 550 560 570 580
pF1KB3 LWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHN
:::.: :::::::::.:::::::::::.:::::::::::::.::. :::..:::: ::
NP_000 LWPTYGGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDV
530 540 550 560 570 580
590 600 610 620 630 640
pF1KB3 VHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGK
:::.::.::::::.:. :::::::::::::.::::::::.::::::::::::::::::::
NP_000 VHLHHILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGK
590 600 610 620 630 640
650 660 670 680 690 700
pF1KB3 IFQAAKGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQ
:::::: :::.::::::::::::::::::::::::::.::.::.: ::.:.::::.::.:
NP_000 IFQAAKDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQ
650 660 670 680 690 700
710 720 730 740
pF1KB3 LAGIPKMQQRLNELCKILGEDSVLKTIKNEDETS
::::::::.::.:::.::::
NP_000 LAGIPKMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST
710 720 730 740
>>XP_016857441 (OMIM: 170995,616278) PREDICTED: ATP-bind (586 aa)
initn: 1503 init1: 906 opt: 1041 Z-score: 1123.0 bits: 218.1 E(85289): 8.2e-56
Smith-Waterman score: 1515; 41.3% identity (72.0% similar) in 596 aa overlap (95-688:1-577)
70 80 90 100 110 120
pF1KB3 ILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYV
. :. :::.: : .: :.:::. ....
XP_016 MVPRTFCKETGYLVLIAVMLVSRTYCDVWM
10 20 30
130 140 150 160 170 180
pF1KB3 AGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIP-ATFVNSAIRYLECKLALAFRTRLVDHA
.: ...: . . : . . . .. :.: ..::. ..: .: : ::.::. .
XP_016 IQ-NGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYL
40 50 60 70 80
190 200 210 220 230 240
pF1KB3 YETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLI
:: :. ::::. :.:.:.::::: ::.:. : .::. :::::.::.::..: . :
XP_016 YEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKL-
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB3 QTATSRGASPIGP-TLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIAN
... ::. :: ...: ::: .. : .::.. : . .: :::.::.:.:
XP_016 --TSAIGAQ--GPASMMAYLVV--SGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITN
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB3 VEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMVAI
:::::: :.: : . ... .. :..... .. :. . .:.... ::. . : ..:.
XP_016 SEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSR
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB3 PIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTAR
:.. . . . . :: : . . .: ..:. ::. . .:.:.:::.:::
XP_016 PFLDLS-----HPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTAR
270 280 290 300 310
430 440 450 460 470 480
pF1KB3 VYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICEN
. ... :. ....: :.:: : :. . . .:..: .:: . :..: .:. : ..
XP_016 ITELMQVLKDLNHGKYERTMVSQQEK--GIEGVQV-IPL---IPGAGEIIIADNIIKFDH
320 330 340 350 360 370
490 500 510 520 530 540
pF1KB3 VPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQH
::. :: :.:. :::.:. : ..:: ::::::::::::.:. :::.. : : :: .
XP_016 VPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGK
380 390 400 410 420 430
550 560 570 580 590 600
pF1KB3 MFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAV
.::.::::::.::.:::::::::. .:.. :: .: :.. : ::.: ::..::::::.:
XP_016 LFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSV
440 450 460 470 480 490
610 620 630 640 650 660
pF1KB3 MDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSIT
.:: :::::::::::.:::.:::::..:.:::::::::.:::: :.. . .::.:....
XP_016 QDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVS
500 510 520 530 540 550
670 680 690 700 710 720
pF1KB3 HRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCK
:: ::::.: . :..::.:...:.:.
XP_016 HRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS
560 570 580
>>XP_016857442 (OMIM: 170995,616278) PREDICTED: ATP-bind (586 aa)
initn: 1503 init1: 906 opt: 1041 Z-score: 1123.0 bits: 218.1 E(85289): 8.2e-56
Smith-Waterman score: 1515; 41.3% identity (72.0% similar) in 596 aa overlap (95-688:1-577)
70 80 90 100 110 120
pF1KB3 ILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYV
. :. :::.: : .: :.:::. ....
XP_016 MVPRTFCKETGYLVLIAVMLVSRTYCDVWM
10 20 30
130 140 150 160 170 180
pF1KB3 AGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIP-ATFVNSAIRYLECKLALAFRTRLVDHA
.: ...: . . : . . . .. :.: ..::. ..: .: : ::.::. .
XP_016 IQ-NGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYL
40 50 60 70 80
190 200 210 220 230 240
pF1KB3 YETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLI
:: :. ::::. :.:.:.::::: ::.:. : .::. :::::.::.::..: . :
XP_016 YEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKL-
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB3 QTATSRGASPIGP-TLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIAN
... ::. :: ...: ::: .. : .::.. : . .: :::.::.:.:
XP_016 --TSAIGAQ--GPASMMAYLVV--SGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITN
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB3 VEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMVAI
:::::: :.: : . ... .. :..... .. :. . .:.... ::. . : ..:.
XP_016 SEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSR
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB3 PIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTAR
:.. . . . . :: : . . .: ..:. ::. . .:.:.:::.:::
XP_016 PFLDLS-----HPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTAR
270 280 290 300 310
430 440 450 460 470 480
pF1KB3 VYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICEN
. ... :. ....: :.:: : :. . . .:..: .:: . :..: .:. : ..
XP_016 ITELMQVLKDLNHGKYERTMVSQQEK--GIEGVQV-IPL---IPGAGEIIIADNIIKFDH
320 330 340 350 360 370
490 500 510 520 530 540
pF1KB3 VPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQH
::. :: :.:. :::.:. : ..:: ::::::::::::.:. :::.. : : :: .
XP_016 VPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGK
380 390 400 410 420 430
550 560 570 580 590 600
pF1KB3 MFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAV
.::.::::::.::.:::::::::. .:.. :: .: :.. : ::.: ::..::::::.:
XP_016 LFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSV
440 450 460 470 480 490
610 620 630 640 650 660
pF1KB3 MDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSIT
.:: :::::::::::.:::.:::::..:.:::::::::.:::: :.. . .::.:....
XP_016 QDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVS
500 510 520 530 540 550
670 680 690 700 710 720
pF1KB3 HRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCK
:: ::::.: . :..::.:...:.:.
XP_016 HRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS
560 570 580
>>XP_016857443 (OMIM: 170995,616278) PREDICTED: ATP-bind (586 aa)
initn: 1503 init1: 906 opt: 1041 Z-score: 1123.0 bits: 218.1 E(85289): 8.2e-56
Smith-Waterman score: 1515; 41.3% identity (72.0% similar) in 596 aa overlap (95-688:1-577)
70 80 90 100 110 120
pF1KB3 ILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYV
. :. :::.: : .: :.:::. ....
XP_016 MVPRTFCKETGYLVLIAVMLVSRTYCDVWM
10 20 30
130 140 150 160 170 180
pF1KB3 AGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIP-ATFVNSAIRYLECKLALAFRTRLVDHA
.: ...: . . : . . . .. :.: ..::. ..: .: : ::.::. .
XP_016 IQ-NGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYL
40 50 60 70 80
190 200 210 220 230 240
pF1KB3 YETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLTSYTLI
:: :. ::::. :.:.:.::::: ::.:. : .::. :::::.::.::..: . :
XP_016 YEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKL-
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB3 QTATSRGASPIGP-TLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIAN
... ::. :: ...: ::: .. : .::.. : . .: :::.::.:.:
XP_016 --TSAIGAQ--GPASMMAYLVV--SGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITN
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB3 VEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGLIMVAI
:::::: :.: : . ... .. :..... .. :. . .:.... ::. . : ..:.
XP_016 SEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSR
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB3 PIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTAR
:.. . . . . :: : . . .: ..:. ::. . .:.:.:::.:::
XP_016 PFLDLS-----HPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTAR
270 280 290 300 310
430 440 450 460 470 480
pF1KB3 VYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHGIICEN
. ... :. ....: :.:: : :. . . .:..: .:: . :..: .:. : ..
XP_016 ITELMQVLKDLNHGKYERTMVSQQEK--GIEGVQV-IPL---IPGAGEIIIADNIIKFDH
320 330 340 350 360 370
490 500 510 520 530 540
pF1KB3 VPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQH
::. :: :.:. :::.:. : ..:: ::::::::::::.:. :::.. : : :: .
XP_016 VPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGK
380 390 400 410 420 430
550 560 570 580 590 600
pF1KB3 MFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREGGWDAV
.::.::::::.::.:::::::::. .:.. :: .: :.. : ::.: ::..::::::.:
XP_016 LFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSV
440 450 460 470 480 490
610 620 630 640 650 660
pF1KB3 MDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGISLLSIT
.:: :::::::::::.:::.:::::..:.:::::::::.:::: :.. . .::.:....
XP_016 QDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVS
500 510 520 530 540 550
670 680 690 700 710 720
pF1KB3 HRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCK
:: ::::.: . :..::.:...:.:.
XP_016 HRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS
560 570 580
>>NP_002849 (OMIM: 170995,616278) ATP-binding cassette s (659 aa)
initn: 1539 init1: 906 opt: 1041 Z-score: 1122.3 bits: 218.1 E(85289): 9e-56
Smith-Waterman score: 1579; 40.3% identity (70.1% similar) in 670 aa overlap (22-688:11-650)
10 20 30 40 50
pF1KB3 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSG-HGKKKAAAYPA
: . :..::. : : . :: . : :::: .. :
NP_002 MAAFSKYLTARNSSLAGAAFLLLCL---LHKRRRALGLHGKK--SGKPP
10 20 30 40
60 70 80 90 100 110
pF1KB3 AENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTF
.:.: : :. :. ::..:... ::. :. :::.: : .: :.:::.
NP_002 LQNNE----KEGKKERAV--VDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTY
50 60 70 80 90
120 130 140 150 160 170
pF1KB3 LSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIP-ATFVNSAIRYLECKLALAFRTR
.... .: ...: . . : . . . .. :.: ..::. ..: .: : ::.:
NP_002 CDVWMIQ-NGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB3 LVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLT
:. . :: :. ::::. :.:.:.::::: ::.:. : .::. :::::.::.::..:
NP_002 LTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLY
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB3 SYTLIQTATSRGASPIGP-TLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHS
. : ... ::. :: ...: ::: .. : .::.. : . .: :::.:
NP_002 IFKL---TSAIGAQ--GPASMMAYLVV--SGLFLTRLRRPIGKMTITEQKYEGEYRYVNS
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB3 RIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGL
:.:.: :::::: :.: : . ... .. :..... .. :. . .:.... ::. . :
NP_002 RLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGY
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB3 IMVAIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELA
..:. :.. . . . . :: : . . .: ..:. ::. . .:.:.::
NP_002 LVVSRPFLDLS-----HPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLA
340 350 360 370 380
420 430 440 450 460 470
pF1KB3 GYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHG
:.:::. ... :. ....: :.:: : :. .. .:..: .:: . :..: .:.
NP_002 GFTARITELMQVLKDLNHGKYERTMVSQQEKG--IEGVQV-IPL---IPGAGEIIIADNI
390 400 410 420 430
480 490 500 510 520 530
pF1KB3 IICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYK
: ..::. :: :.:. :::.:. : ..:: ::::::::::::.:. :::.. : : :
NP_002 IKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTK
440 450 460 470 480 490
540 550 560 570 580 590
pF1KB3 PPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREG
: ..::.::::::.::.:::::::::. .:.. :: .: :.. : ::.: ::..:::
NP_002 PERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREG
500 510 520 530 540 550
600 610 620 630 640 650
pF1KB3 GWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGIS
:::.:.:: :::::::::::.:::.:::::..:.:::::::::.:::: :.. . .::.
NP_002 GWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGIT
560 570 580 590 600 610
660 670 680 690 700 710
pF1KB3 LLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRL
:....:: ::::.: . :..::.:...:.:.
NP_002 LFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS
620 630 640 650
720 730 740
pF1KB3 NELCKILGEDSVLKTIKNEDETS
740 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:34:35 2016 done: Sat Nov 5 02:34:36 2016
Total Scan time: 10.110 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]