Result of FASTA (ccds) for
pF1KB3244
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3244, 2162 aa
1>>>pF1KB3244 2162 - 2162 aa - 2162 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2660+/-0.00125; mu= 6.2012+/- 0.075
mean_var=193.9299+/-39.960, 0's: 0 Z-trim(107.8): 33 B-trim: 2 in 1/49
Lambda= 0.092098
statistics sampled from 9784 (9803) to 9784 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.301), width: 16
Scan time: 8.080
The best scores are: opt bits E(32554)
CCDS77396.1 CAD gene_id:790|Hs108|chr2 (2162) 14382 1925.4 0
CCDS1742.1 CAD gene_id:790|Hs108|chr2 (2225) 10262 1378.0 0
CCDS46506.1 CPS1 gene_id:1373|Hs108|chr2 (1049) 2170 302.6 5.9e-81
CCDS2393.1 CPS1 gene_id:1373|Hs108|chr2 (1500) 2170 302.7 8e-81
CCDS46505.1 CPS1 gene_id:1373|Hs108|chr2 (1506) 2170 302.7 8e-81
>>CCDS77396.1 CAD gene_id:790|Hs108|chr2 (2162 aa)
initn: 14382 init1: 14382 opt: 14382 Z-score: 10331.4 bits: 1925.4 E(32554): 0
Smith-Waterman score: 14382; 100.0% identity (100.0% similar) in 2162 aa overlap (1-2162:1-2162)
10 20 30 40 50 60
pF1KB3 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GIPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 GIPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 TRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 TDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 TDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 TAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 TAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 AQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 EYEVVRDAYGNCVTYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 EYEVVRDAYGNCVTYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 GGTAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 GGTAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 DENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMKRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 DENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMKRI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 IAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 IAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 DTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 DTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 KMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 KMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNM
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 AMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 AMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGY
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 PCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 GVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 GVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 IAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVGVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 IAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVGVKV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 PQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB3 NKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 NKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB3 LAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 LAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQI
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB3 GPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 GPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAM
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB3 PNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNETF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNETF
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB3 SELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 SELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEILL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB3 IKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 IKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVIDCF
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB3 ASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 ASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLP
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB3 PQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPP
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB3 GYGQDVRKWPQGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASDPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 GYGQDVRKWPQGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASDPGL
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB3 PAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 PAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHSLVG
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB3 QHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSFAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSFAAA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB3 MARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 MARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRRPVI
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB3 NAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 NAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRY
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB3 VAPPSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEACFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 VAPPSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEACFG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB3 QFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 QFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLG
2110 2120 2130 2140 2150 2160
pF1KB3 RF
::
CCDS77 RF
>>CCDS1742.1 CAD gene_id:790|Hs108|chr2 (2225 aa)
initn: 10262 init1: 10262 opt: 10262 Z-score: 7372.6 bits: 1378.0 E(32554): 0
Smith-Waterman score: 14055; 97.1% identity (97.1% similar) in 2194 aa overlap (32-2162:32-2225)
10 20 30 40 50 60
pF1KB3 AALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYG
::::::::::::::::::::::::::::::
CCDS17 AALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 IPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 IPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVDT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 RELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 RELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 DCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 EPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 EPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVET
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 DSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 DSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 AGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 AGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAIK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 ALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 LNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 QAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 QAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEIE
550 560 570 580 590 600
610
pF1KB3 YEVVRDAYGNCVT-----------------------------------------------
:::::::::::::
CCDS17 YEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGI
610 620 630 640 650 660
620 630 640 650
pF1KB3 ----------------YYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNS
::::::::::::::::::::::::::::::::::::::::::::
CCDS17 VGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNS
670 680 690 700 710 720
660 670 680 690 700 710
pF1KB3 VTGGTAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 VTGGTAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALR
730 740 750 760 770 780
720 730 740 750 760 770
pF1KB3 MVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 MVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMK
790 800 810 820 830 840
780 790 800 810 820 830
pF1KB3 RIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 RIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVK
850 860 870 880 890 900
840 850 860 870 880 890
pF1KB3 QIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 QIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQ
910 920 930 940 950 960
900 910 920 930 940 950
pF1KB3 LRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 LRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPN
970 980 990 1000 1010 1020
960 970 980 990 1000 1010
pF1KB3 NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTV
1030 1040 1050 1060 1070 1080
1020 1030 1040 1050 1060 1070
pF1KB3 GYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 GYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVA
1090 1100 1110 1120 1130 1140
1080 1090 1100 1110 1120 1130
pF1KB3 SDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 SDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNL
1150 1160 1170 1180 1190 1200
1140 1150 1160 1170 1180 1190
pF1KB3 QLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 QLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVGV
1210 1220 1230 1240 1250 1260
1200 1210 1220 1230 1240 1250
pF1KB3 KVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 KVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGS
1270 1280 1290 1300 1310 1320
1260 1270 1280 1290 1300 1310
pF1KB3 YKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 YKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSIL
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KB3 EQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 EQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALG
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KB3 QIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 QIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVC
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KB3 AMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 AMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNE
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KB3 TFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 TFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSVHICHVARKEEI
1570 1580 1590 1600 1610 1620
1560 1570 1580 1590 1600 1610
pF1KB3 LLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 LLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVID
1630 1640 1650 1660 1670 1680
1620 1630 1640 1650 1660 1670
pF1KB3 CFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 CFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFH
1690 1700 1710 1720 1730 1740
1680 1690 1700 1710 1720 1730
pF1KB3 LPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 LPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLV
1750 1760 1770 1780 1790 1800
1740 1750 1760 1770 1780 1790
pF1KB3 PPGYGQDVRKWPQGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 PPGYGQDVRKWPQGAVPQLPPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASDP
1810 1820 1830 1840 1850 1860
1800 1810 1820 1830 1840 1850
pF1KB3 GLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 GLPAEEPKEKSSRKVAEPELMGTPDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHSL
1870 1880 1890 1900 1910 1920
1860 1870 1880 1890 1900 1910
pF1KB3 VGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 VGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSFA
1930 1940 1950 1960 1970 1980
1920 1930 1940 1950 1960 1970
pF1KB3 AAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 AAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRRP
1990 2000 2010 2020 2030 2040
1980 1990 2000 2010 2020 2030
pF1KB3 VINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 VINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSL
2050 2060 2070 2080 2090 2100
2040 2050 2060 2070 2080 2090
pF1KB3 RYVAPPSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 RYVAPPSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEAC
2110 2120 2130 2140 2150 2160
2100 2110 2120 2130 2140 2150
pF1KB3 FGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS17 FGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATV
2170 2180 2190 2200 2210 2220
2160
pF1KB3 LGRF
::::
CCDS17 LGRF
>>CCDS46506.1 CPS1 gene_id:1373|Hs108|chr2 (1049 aa)
initn: 2868 init1: 1545 opt: 2170 Z-score: 1566.9 bits: 302.6 E(32554): 5.9e-81
Smith-Waterman score: 3069; 48.8% identity (73.2% similar) in 1037 aa overlap (423-1377:1-1026)
400 410 420 430 440
pF1KB3 PRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQ-GL--ADK
.::::..:.:.:::::.:::.. :: ::
CCDS46 MKEENVKTVLMNPNIASVQTNEVGLKQADT
10 20 30
450 460 470 480 490 500
pF1KB3 VYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETI
::::::::..::.::. :.:::..: .:::::::::::: : ::: .:::.:::: ::.:
CCDS46 VYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESI
40 50 60 70 80 90
510 520 530 540 550 560
pF1KB3 ELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFAS
::::. :. .. ::.:..::: :..:.:.: ::. .::::..:.:.::::::::.
CCDS46 MATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICP
100 110 120 130 140 150
570 580 590 600 610
pF1KB3 NREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVT---------------
::: : : . ::: :.:.::.::. ::::::::::::: ::::
CCDS46 NRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTG
160 170 180 190 200 210
620
pF1KB3 ------------------------------------------------YYIIEVNARLSR
: ::::::::::
CCDS46 DSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSR
220 230 240 250 260 270
630 640 650 660 670 680
pF1KB3 SSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAA-FEPSVDYCVVKIPRWDLSKF
::::::::::::::..:::.::::::::..: :.: :.: ::::.:: :.:::::::..:
CCDS46 SSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRF
280 290 300 310 320 330
690 700 710 720 730
pF1KB3 LRVSTKIGSCMKSVGEVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVS-------DM-
.:..::: ::::::::.:::.:::.::::::: . :: . :.. :.
CCDS46 HGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRL-PMNKEWPSNLDLR
340 350 360 370 380
740 750 760 770 780 790
pF1KB3 -ELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQPLP
:: :.. ::...: :. ..:.:.. .:: ::.:::..:. :. . :. .. .
CCDS46 KELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMT
390 400 410 420 430 440
800 810 820 830 840 850
pF1KB3 PDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYL
. :..:: .:::::::. . :: .:.:: . .: : ::::::.:::.:. :::::.
CCDS46 EETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYV
450 460 470 480 490 500
860 870 880 890 900 910
pF1KB3 TYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETV
:: : ::..: ..::: : :.::::::::::::. :. ::..: ::..:: :::::
CCDS46 TYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETV
510 520 530 540 550 560
920 930 940 950 960 970
pF1KB3 STDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSP
:::.: ::.:::.:.:.: ..:::. : : :.:.:::.:::.:. :... ...::::
CCDS46 STDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSP
570 580 590 600 610 620
980 990 1000 1010 1020 1030
pF1KB3 EAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMN
:: ::.: :: .:: . ..: :. .. :. : .: ..: :::..::::::::.:::
CCDS46 LQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMN
630 640 650 660 670 680
1040 1050 1060 1070 1080 1090
pF1KB3 VAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAG
:.... ....:: :. ::.:::::..::.. :.:...:::..:: : . :::::::.::
CCDS46 VVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAG
690 700 710 720 730 740
1100 1110 1120 1130 1140 1150
pF1KB3 VHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRV
::::::::. : : :. ..:..: .. ... . ..::::.:...: ... :::::.:.
CCDS46 VHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRA
750 760 770 780 790 800
1160 1170 1180 1190 1200 1210
pF1KB3 SRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMT------GSGVVGVKVPQFSFSRLAG
::::::::::::::.. .::.:..::.:. : : . :..:.:.::. ::
CCDS46 SRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRD
810 820 830 840 850 860
1220 1230 1240 1250 1260 1270
pF1KB3 ADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVR
:: .: ::.:::::: :::. :.::::::::::::.:.::. : . . . ..: ...
CCDS46 ADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGI-QQSFRPRFLGVAE
870 880 890 900 910 920
1280 1290 1300 1310 1320 1330
pF1KB3 LLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQLAEKNFELVI
:.. :..:.:. .:.:. . ..: .: : : .: :. : :: . . . ...:::
CCDS46 QLHNEGFKLFATEATSDWLNANNVPATPVAWPSQE---GQNPSLSSIRKLIRDGSIDLVI
930 940 950 960 970 980
1340 1350 1360 1370 1380 1390
pF1KB3 NLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHV
:: . ..:: .: :: :.: ..::. ... ::::.::.
CCDS46 NLPNNN------TKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFH
990 1000 1010 1020 1030
1400 1410 1420 1430 1440 1450
pF1KB3 DCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDA
CCDS46 YRQYSAGKAA
1040
>>CCDS2393.1 CPS1 gene_id:1373|Hs108|chr2 (1500 aa)
initn: 3922 init1: 1545 opt: 2170 Z-score: 1564.5 bits: 302.7 E(32554): 8e-81
Smith-Waterman score: 4311; 48.5% identity (73.5% similar) in 1432 aa overlap (29-1377:73-1477)
10 20 30 40 50
pF1KB3 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIG
:.::. :::::.:::.::.:::... :.::
CCDS23 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIG
50 60 70 80 90 100
60 70 80 90 100 110
pF1KB3 NYGIPPDE-MDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQ
: : : .::.:: :..::.::.:..:.: . .:: ::..: .:::.. .:..
CCDS23 NGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIY
110 120 130 140 150 160
120 130 140 150 160 170
pF1KB3 GVDTRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPR
::::: ::: .:..:..:::. .: .: . :.::: . :. ::: : .:.. :. .
CCDS23 GVDTRMLTKIIRDKGTMLGKIEFEG-QP--VDFVDPNKQNLIAEVSTKDVKVYGKGNPTK
170 180 190 200 210
180 190 200 210 220 230
pF1KB3 ILALDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLS
..:.:::.: : :: : .::::: .:::.: . ..::.:.....:::.:: .....
CCDS23 VVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVR
220 230 240 250 260 270
240 250 260 270 280 290
pF1KB3 RVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGF
..: .:.::: :. . .:: ::::::: ..:::.::: : . . . :.:.::::.
CCDS23 KILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGY
280 290 300 310 320 330
300 310 320 330 340 350
pF1KB3 AVETDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETV
:.. ..::: : :::.:.:: .::::.:.: :::.:::::: :: : : ::: :. .
CCDS23 ALD-NTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLI
340 350 360 370 380 390
360 370 380 390 400 410
pF1KB3 KEATAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGS
:.. : . .: : :.. . . :::::::::::::::::::::::
CCDS23 KKGKATT---------ITSVLPKPALVASRVEVS---KVLILGSGGLSIGQAGEFDYSGS
400 410 420 430 440
420 430 440 450 460 470
pF1KB3 QAIKALKEENIQTLLINPNIATVQTSQ-GL--ADKVYFLPITPHYVTQVIRNERPDGVLL
::.::.::::..:.:.:::::.:::.. :: :: ::::::::..::.::. :.:::..:
CCDS23 QAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLIL
450 460 470 480 490 500
480 490 500 510 520 530
pF1KB3 TFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEA
.:::::::::::: : ::: .:::.:::: ::.: ::::. :. .. ::.:..::: :
CCDS23 GMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFA
510 520 530 540 550 560
540 550 560 570 580 590
pF1KB3 ANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSL
..:.:.: ::. .::::..:.:.::::::::. ::: : : . ::: :.:.::.::.
CCDS23 VESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSV
570 580 590 600 610 620
600 610
pF1KB3 KGWKEIEYEVVRDAYGNCVT----------------------------------------
::::::::::::: ::::
CCDS23 TGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSIN
630 640 650 660 670 680
620 630 640 650
pF1KB3 -----------------------YYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIP
: ::::::::::::::::::::::::..:::.:::::
CCDS23 VVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIP
690 700 710 720 730 740
660 670 680 690 700 710
pF1KB3 LPELRNSVTGGTAA-FEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFE
:::..: :.: :.: ::::.:: :.:::::::..: .:..::: ::::::::.:::.::
CCDS23 LPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFE
750 760 770 780 790 800
720 730 740 750 760
pF1KB3 EAFQKALRMVDENCVGFDHTVKPVS-------DM--ELETPTDKRIFVVAAALWAGYSVD
:.::::::: . :: . :.. :. :: :.. ::...: :. ..:.:
CCDS23 ESFQKALRMCHPSIEGFTPRL-PMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLD
810 820 830 840 850 860
770 780 790 800 810 820
pF1KB3 RLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTE
.. .:: ::.:::..:. :. . :. .. . . :..:: .:::::::. . ::
CCDS23 EIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTE
870 880 890 900 910 920
830 840 850 860 870 880
pF1KB3 LAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYR
.:.:: . .: : ::::::.:::.:. :::::.:: : ::..: ..::: : :.
CCDS23 AQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYH
930 940 950 960 970 980
890 900 910 920 930 940
pF1KB3 IGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYE
::::::::::::. :. ::..: ::..:: ::::::::.: ::.:::.:.:.: ..:::.
CCDS23 IGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYH
990 1000 1010 1020 1030 1040
950 960 970 980 990 1000
pF1KB3 LENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQ
: : :.:.:::.:::.:. :... ...:::: :: ::.: :: .:: . ..:
CCDS23 QEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAP
1050 1060 1070 1080 1090 1100
1010 1020 1030 1040 1050 1060
pF1KB3 WRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVV
:. .. :. : .: ..: :::..::::::::.::::.... ....:: :. ::.:::::
CCDS23 WKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVV
1110 1120 1130 1140 1150 1160
1070 1080 1090 1100 1110 1120
pF1KB3 ISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKA
..::.. :.:...:::..:: : . :::::::.::::::::::. : : :. ..:..:
CCDS23 LTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKD
1170 1180 1190 1200 1210 1220
1130 1140 1150 1160 1170 1180
pF1KB3 IVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMG
.. ... . ..::::.:...: ... :::::.:.::::::::::::::.. .::.:..:
CCDS23 ATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIG
1230 1240 1250 1260 1270 1280
1190 1200 1210 1220 1230
pF1KB3 EEVEPVGLMT------GSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEA
:.:. : : . :..:.:.::. :: :: .: ::.:::::: :::. :
CCDS23 ENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTA
1290 1300 1310 1320 1330 1340
1240 1250 1260 1270 1280 1290
pF1KB3 YLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVK
.::::::::::::.:.::. : . . . ..: ... :.. :..:.:. .:.:. . ..:
CCDS23 FLKAMLSTGFKIPQKGILIGI-QQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVP
1350 1360 1370 1380 1390 1400
1300 1310 1320 1330 1340 1350
pF1KB3 VTAVDWHFEEAVDGECPPQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRL
.: : : .: :. : :: . . . ...::::: . ..:: .: ::
CCDS23 ATPVAWPSQE---GQNPSLSSIRKLIRDGSIDLVINLPNNN------TKFVHDNYVIRRT
1410 1420 1430 1440 1450
1360 1370 1380 1390 1400 1410
pF1KB3 AADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPG
:.: ..::. ... ::::.::.
CCDS23 AVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA
1460 1470 1480 1490 1500
>>CCDS46505.1 CPS1 gene_id:1373|Hs108|chr2 (1506 aa)
initn: 3922 init1: 1545 opt: 2170 Z-score: 1564.5 bits: 302.7 E(32554): 8e-81
Smith-Waterman score: 4311; 48.5% identity (73.5% similar) in 1432 aa overlap (29-1377:79-1483)
10 20 30 40 50
pF1KB3 MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIG
:.::. :::::.:::.::.:::... :.::
CCDS46 AQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIG
50 60 70 80 90 100
60 70 80 90 100 110
pF1KB3 NYGIPPDE-MDEFGLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQ
: : : .::.:: :..::.::.:..:.: . .:: ::..: .:::.. .:..
CCDS46 NGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIY
110 120 130 140 150 160
120 130 140 150 160 170
pF1KB3 GVDTRELTKKLREQGSLLGKLVQNGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPR
::::: ::: .:..:..:::. .: .: . :.::: . :. ::: : .:.. :. .
CCDS46 GVDTRMLTKIIRDKGTMLGKIEFEG-QP--VDFVDPNKQNLIAEVSTKDVKVYGKGNPTK
170 180 190 200 210 220
180 190 200 210 220 230
pF1KB3 ILALDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLS
..:.:::.: : :: : .::::: .:::.: . ..::.:.....:::.:: .....
CCDS46 VVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVR
230 240 250 260 270 280
240 250 260 270 280 290
pF1KB3 RVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGF
..: .:.::: :. . .:: ::::::: ..:::.::: : . . . :.:.::::.
CCDS46 KILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGY
290 300 310 320 330 340
300 310 320 330 340 350
pF1KB3 AVETDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLFDIFLETV
:.. ..::: : :::.:.:: .::::.:.: :::.:::::: :: : : ::: :. .
CCDS46 ALD-NTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLI
350 360 370 380 390 400
360 370 380 390 400 410
pF1KB3 KEATAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGS
:.. : . .: : :.. . . :::::::::::::::::::::::
CCDS46 KKGKATT---------ITSVLPKPALVASRVEVS---KVLILGSGGLSIGQAGEFDYSGS
410 420 430 440 450
420 430 440 450 460 470
pF1KB3 QAIKALKEENIQTLLINPNIATVQTSQ-GL--ADKVYFLPITPHYVTQVIRNERPDGVLL
::.::.::::..:.:.:::::.:::.. :: :: ::::::::..::.::. :.:::..:
CCDS46 QAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLIL
460 470 480 490 500 510
480 490 500 510 520 530
pF1KB3 TFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEA
.:::::::::::: : ::: .:::.:::: ::.: ::::. :. .. ::.:..::: :
CCDS46 GMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFA
520 530 540 550 560 570
540 550 560 570 580 590
pF1KB3 ANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSL
..:.:.: ::. .::::..:.:.::::::::. ::: : : . ::: :.:.::.::.
CCDS46 VESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSV
580 590 600 610 620 630
600 610
pF1KB3 KGWKEIEYEVVRDAYGNCVT----------------------------------------
::::::::::::: ::::
CCDS46 TGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSIN
640 650 660 670 680 690
620 630 640 650
pF1KB3 -----------------------YYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIP
: ::::::::::::::::::::::::..:::.:::::
CCDS46 VVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIP
700 710 720 730 740 750
660 670 680 690 700 710
pF1KB3 LPELRNSVTGGTAA-FEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFE
:::..: :.: :.: ::::.:: :.:::::::..: .:..::: ::::::::.:::.::
CCDS46 LPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFE
760 770 780 790 800 810
720 730 740 750 760
pF1KB3 EAFQKALRMVDENCVGFDHTVKPVS-------DM--ELETPTDKRIFVVAAALWAGYSVD
:.::::::: . :: . :.. :. :: :.. ::...: :. ..:.:
CCDS46 ESFQKALRMCHPSIEGFTPRL-PMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLD
820 830 840 850 860 870
770 780 790 800 810 820
pF1KB3 RLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTE
.. .:: ::.:::..:. :. . :. .. . . :..:: .:::::::. . ::
CCDS46 EIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTE
880 890 900 910 920 930
830 840 850 860 870 880
pF1KB3 LAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYR
.:.:: . .: : ::::::.:::.:. :::::.:: : ::..: ..::: : :.
CCDS46 AQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYH
940 950 960 970 980 990
890 900 910 920 930 940
pF1KB3 IGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYE
::::::::::::. :. ::..: ::..:: ::::::::.: ::.:::.:.:.: ..:::.
CCDS46 IGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYH
1000 1010 1020 1030 1040 1050
950 960 970 980 990 1000
pF1KB3 LENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQ
: : :.:.:::.:::.:. :... ...:::: :: ::.: :: .:: . ..:
CCDS46 QEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAP
1060 1070 1080 1090 1100 1110
1010 1020 1030 1040 1050 1060
pF1KB3 WRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVV
:. .. :. : .: ..: :::..::::::::.::::.... ....:: :. ::.:::::
CCDS46 WKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVV
1120 1130 1140 1150 1160 1170
1070 1080 1090 1100 1110 1120
pF1KB3 ISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKA
..::.. :.:...:::..:: : . :::::::.::::::::::. : : :. ..:..:
CCDS46 LTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKD
1180 1190 1200 1210 1220 1230
1130 1140 1150 1160 1170 1180
pF1KB3 IVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMG
.. ... . ..::::.:...: ... :::::.:.::::::::::::::.. .::.:..:
CCDS46 ATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIG
1240 1250 1260 1270 1280 1290
1190 1200 1210 1220 1230
pF1KB3 EEVEPVGLMT------GSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEA
:.:. : : . :..:.:.::. :: :: .: ::.:::::: :::. :
CCDS46 ENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTA
1300 1310 1320 1330 1340 1350
1240 1250 1260 1270 1280 1290
pF1KB3 YLKAMLSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVK
.::::::::::::.:.::. : . . . ..: ... :.. :..:.:. .:.:. . ..:
CCDS46 FLKAMLSTGFKIPQKGILIGI-QQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVP
1360 1370 1380 1390 1400 1410
1300 1310 1320 1330 1340 1350
pF1KB3 VTAVDWHFEEAVDGECPPQRSILEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRL
.: : : .: :. : :: . . . ...::::: . ..:: .: ::
CCDS46 ATPVAWPSQE---GQNPSLSSIRKLIRDGSIDLVINLPNNN------TKFVHDNYVIRRT
1420 1430 1440 1450 1460
1360 1370 1380 1390 1400 1410
pF1KB3 AADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPG
:.: ..::. ... ::::.::.
CCDS46 AVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA
1470 1480 1490 1500
2162 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:51:52 2016 done: Thu Nov 3 20:51:54 2016
Total Scan time: 8.080 Total Display time: 0.830
Function used was FASTA [36.3.4 Apr, 2011]