Result of FASTA (ccds) for
pF1KB3098
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3098, 646 aa
1>>>pF1KB3098 646 - 646 aa - 646 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6678+/-0.00105; mu= -2.2016+/- 0.063
mean_var=413.6495+/-88.856, 0's: 0 Z-trim(115.4): 92 B-trim: 0 in 0/50
Lambda= 0.063061
statistics sampled from 15919 (16004) to 15919 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.492), width: 16
Scan time: 4.260
The best scores are: opt bits E(32554)
CCDS7800.1 WEE1 gene_id:7465|Hs108|chr11 ( 646) 4352 410.4 3.9e-114
CCDS44536.1 WEE1 gene_id:7465|Hs108|chr11 ( 432) 2830 271.7 1.5e-72
CCDS43660.1 WEE2 gene_id:494551|Hs108|chr7 ( 567) 1400 141.8 2.5e-33
>>CCDS7800.1 WEE1 gene_id:7465|Hs108|chr11 (646 aa)
initn: 4352 init1: 4352 opt: 4352 Z-score: 2162.5 bits: 410.4 E(32554): 3.9e-114
Smith-Waterman score: 4352; 100.0% identity (100.0% similar) in 646 aa overlap (1-646:1-646)
10 20 30 40 50 60
pF1KB3 MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 PLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 SSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 KLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 DSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 DSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 ELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 ELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 RYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 SLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 RFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 EFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 EFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKK
550 560 570 580 590 600
610 620 630 640
pF1KB3 AQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 AQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
610 620 630 640
>>CCDS44536.1 WEE1 gene_id:7465|Hs108|chr11 (432 aa)
initn: 2830 init1: 2830 opt: 2830 Z-score: 1416.2 bits: 271.7 E(32554): 1.5e-72
Smith-Waterman score: 2830; 100.0% identity (100.0% similar) in 432 aa overlap (215-646:1-432)
190 200 210 220 230 240
pF1KB3 FDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLL
::::::::::::::::::::::::::::::
CCDS44 MDTEKSGKREFDVRQTPQVNINPFTPDSLL
10 20 30
250 260 270 280 290 300
pF1KB3 LHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEK
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB3 IGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFS
100 110 120 130 140 150
370 380 390 400 410 420
pF1KB3 AWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVH
160 170 180 190 200 210
430 440 450 460 470 480
pF1KB3 MDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLA
220 230 240 250 260 270
490 500 510 520 530 540
pF1KB3 NEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTE
280 290 300 310 320 330
550 560 570 580 590 600
pF1KB3 LLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMA
340 350 360 370 380 390
610 620 630 640
pF1KB3 KAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
::::::::::::::::::::::::::::::::::::::::::
CCDS44 KAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
400 410 420 430
>>CCDS43660.1 WEE2 gene_id:494551|Hs108|chr7 (567 aa)
initn: 1467 init1: 721 opt: 1400 Z-score: 711.7 bits: 141.8 E(32554): 2.5e-33
Smith-Waterman score: 1474; 51.7% identity (72.9% similar) in 484 aa overlap (168-644:92-559)
140 150 160 170 180 190
pF1KB3 FSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSK
:. :. : .. :: :.: :::..::.
CCDS43 NVHELDTSSEKDKESPDQILRTPVSHPLKCPETPAQPDSRS--KLLPSDSPSTPKTMLSR
70 80 90 100 110
200 210 220 230 240 250
pF1KB3 ARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDS---LLLHSSGQCRRR
.... :: . . : : : . . ::::::::.: :.:.:.: .:.
CCDS43 LVISPTGKLPSRGPKHLKLTPAPLKDE--MTSLALVNINPFTPESYKKLFLQSGG--KRK
120 130 140 150 160 170
260 270 280 290 300 310
pF1KB3 KRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVF
: : :.: . : :::: .. :.:: ::: :: :.:::: ::::.:.
CCDS43 IR-------G-DLEEAGPEEGKGGLPAKRCVLRETNMASRYEKEFLEVEKIGVGEFGTVY
180 190 200 210 220
320 330 340 350 360 370
pF1KB3 KCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLI
::.::::::.:::::: : .. .:..::.:::::::::.: :::::.:.:::::::.:
CCDS43 KCIKRLDGCVYAIKRSMKTFTELSNENSALHEVYAHAVLGHHPHVVRYYSSWAEDDHMII
230 240 250 260 270 280
380 390 400 410 420 430
pF1KB3 QNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFI
:::::::::: ::::: . ..:.: .:::.:::.. :: :::. :.::.:::::::::
CCDS43 QNEYCNGGSLQAAISENTKSGNHFEEPKLKDILLQISLGLNYIHNSSMVHLDIKPSNIFI
290 300 310 320 330 340
440 450 460 470 480 490
pF1KB3 SRT--SIPNAASEE-GDEDDW-ASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQE
. : ... :: .: :: : .::.:::::::.: :..:.::::::::::::.:::
CCDS43 CHKMQSESSGVIEEVENEADWFLSANVMYKIGDLGHATSINKPKVEEGDSRFLANEILQE
350 360 370 380 390 400
500 510 520 530 540 550
pF1KB3 NYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMI
.: ::::::::::.::.. ::::: :: :: ::.::.: .: .:: ::. :. ::: ::
CCDS43 DYRHLPKADIFALGLTIAVAAGAESLPTNGAAWHHIRKGNFPDVPQELSESFSSLLKNMI
410 420 430 440 450 460
560 570 580 590 600 610
pF1KB3 HPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEE
.:: :.:::: ::....:: . :. :.:. .:: ::::.. :..::..::.:.. .
CCDS43 QPDAEQRPSAAALARNTVLRPSLGKT-EELQQQLNLEKFKTATLERELREAQQAQSP-QG
470 480 490 500 510 520
620 630 640
pF1KB3 RALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
. : .. . : : :.::.: : :: :.:
CCDS43 YTHHGDTGVSGTHTGSRSTKRLVGGKSARSSSFTSGEREPLH
530 540 550 560
646 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:22:26 2016 done: Thu Nov 3 12:22:26 2016
Total Scan time: 4.260 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]