FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3051, 1215 aa 1>>>pF1KB3051 1215 - 1215 aa - 1215 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.0787+/-0.00116; mu= -2.7133+/- 0.070 mean_var=317.4757+/-63.669, 0's: 0 Z-trim(112.0): 35 B-trim: 0 in 0/53 Lambda= 0.071981 statistics sampled from 12829 (12848) to 12829 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.395), width: 16 Scan time: 4.510 The best scores are: opt bits E(32554) CCDS58638.1 AP3D1 gene_id:8943|Hs108|chr19 (1215) 7920 837.2 0 CCDS42459.1 AP3D1 gene_id:8943|Hs108|chr19 (1153) 5626 599.0 2.2e-170 >>CCDS58638.1 AP3D1 gene_id:8943|Hs108|chr19 (1215 aa) initn: 7920 init1: 7920 opt: 7920 Z-score: 4459.6 bits: 837.2 E(32554): 0 Smith-Waterman score: 7920; 100.0% identity (100.0% similar) in 1215 aa overlap (1-1215:1-1215) 10 20 30 40 50 60 pF1KB3 MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 IIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYIS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 ILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLLASSTQRNGICE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLLASSTQRNGICE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQKLQAKDVPVAEEVSALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQKLQAKDVPVAEEVSALF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 AGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 DEEELARRREARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGLPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DEEELARRREARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGLPM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 SDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 MPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SKKPKKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTGELSVNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SKKPKKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTGELSVNT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 VTTPKDECEDAKTEAQGEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VTTPKDECEDAKTEAQGEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 EEAAGEPVQNGAPEEEQLPPESSYSLLAENSYVKMTCDIRGSLQEDSQVTVAIVLENRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EEAAGEPVQNGAPEEEQLPPESSYSLLAENSYVKMTCDIRGSLQEDSQVTVAIVLENRSS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 SILKGMELSVLDSLNARMARPQGSSVHDGVPVPFQLPPGVSNEAQYVFTIQSIVMAQKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SILKGMELSVLDSLNARMARPQGSSVHDGVPVPFQLPPGVSNEAQYVFTIQSIVMAQKLK 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB3 GTLSFIAKNDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMSSIKVDGIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GTLSFIAKNDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMSSIKVDGIR 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB3 MSFQNLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSVDGKCSDSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MSFQNLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSVDGKCSDSTL 1150 1160 1170 1180 1190 1200 1210 pF1KB3 LSNLLEEMKATLAKC ::::::::::::::: CCDS58 LSNLLEEMKATLAKC 1210 >>CCDS42459.1 AP3D1 gene_id:8943|Hs108|chr19 (1153 aa) initn: 5713 init1: 5626 opt: 5626 Z-score: 3172.4 bits: 599.0 E(32554): 2.2e-170 Smith-Waterman score: 7358; 94.9% identity (94.9% similar) in 1215 aa overlap (1-1215:1-1153) 10 20 30 40 50 60 pF1KB3 MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 KLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 IIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 LDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYIS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 ILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLLASSTQRNGICE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLLASSTQRNGICE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 VLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 GEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQKLQAKDVPVAEEVSALF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQKLQAKDVPVAEEVSALF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 AGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 AGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 DEEELARRREARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGLPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 DEEELARRREARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGLPM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 SDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 MPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 SKKPKKKEKKHKEKERDKEKKKEKEKKAEDLDFWLSTTPPPAPAPAPAPVPSTGELSVNT ::::::::::::::::::::::::::: CCDS42 SKKPKKKEKKHKEKERDKEKKKEKEKK--------------------------------- 850 860 910 920 930 940 950 960 pF1KB3 VTTPKDECEDAKTEAQGEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGS ::::::::::::::::::::::::::::::: CCDS42 -----------------------------KSPKPKKKKHRKEKEERTKGKKKSKKQPPGS 870 880 890 970 980 990 1000 1010 1020 pF1KB3 EEAAGEPVQNGAPEEEQLPPESSYSLLAENSYVKMTCDIRGSLQEDSQVTVAIVLENRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EEAAGEPVQNGAPEEEQLPPESSYSLLAENSYVKMTCDIRGSLQEDSQVTVAIVLENRSS 900 910 920 930 940 950 1030 1040 1050 1060 1070 1080 pF1KB3 SILKGMELSVLDSLNARMARPQGSSVHDGVPVPFQLPPGVSNEAQYVFTIQSIVMAQKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SILKGMELSVLDSLNARMARPQGSSVHDGVPVPFQLPPGVSNEAQYVFTIQSIVMAQKLK 960 970 980 990 1000 1010 1090 1100 1110 1120 1130 1140 pF1KB3 GTLSFIAKNDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMSSIKVDGIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GTLSFIAKNDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMSSIKVDGIR 1020 1030 1040 1050 1060 1070 1150 1160 1170 1180 1190 1200 pF1KB3 MSFQNLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSVDGKCSDSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MSFQNLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSVDGKCSDSTL 1080 1090 1100 1110 1120 1130 1210 pF1KB3 LSNLLEEMKATLAKC ::::::::::::::: CCDS42 LSNLLEEMKATLAKC 1140 1150 1215 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 12:16:57 2016 done: Thu Nov 3 12:16:58 2016 Total Scan time: 4.510 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]