Result of FASTA (omim) for
pF1KB3048
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3048, 1342 aa
1>>>pF1KB3048 1342 - 1342 aa - 1342 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7576+/-0.000503; mu= 7.0038+/- 0.031
mean_var=242.8914+/-49.218, 0's: 0 Z-trim(116.3): 539 B-trim: 0 in 0/55
Lambda= 0.082294
statistics sampled from 26712 (27317) to 26712 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.32), width: 16
Scan time: 16.510
The best scores are: opt bits E(85289)
NP_001159737 (OMIM: 150390) latent-transforming gr (1342) 9897 1190.0 0
XP_005264374 (OMIM: 150390) PREDICTED: latent-tran (1668) 9772 1175.2 0
XP_011531161 (OMIM: 150390) PREDICTED: latent-tran (1669) 9759 1173.7 0
NP_000618 (OMIM: 150390) latent-transforming growt (1395) 7097 857.5 0
NP_996826 (OMIM: 150390) latent-transforming growt (1721) 7097 857.6 0
XP_011531162 (OMIM: 150390) PREDICTED: latent-tran (1666) 7080 855.6 0
XP_011531155 (OMIM: 150390) PREDICTED: latent-tran (1722) 7080 855.6 0
XP_011531157 (OMIM: 150390) PREDICTED: latent-tran (1720) 7075 855.0 0
NP_001159738 (OMIM: 150390) latent-transforming gr (1300) 6602 798.7 0
XP_005264375 (OMIM: 150390) PREDICTED: latent-tran (1626) 6482 784.6 0
XP_011531160 (OMIM: 150390) PREDICTED: latent-tran (1680) 6102 739.5 4.7e-212
XP_016859597 (OMIM: 150390) PREDICTED: latent-tran (1681) 5523 670.7 2.3e-191
XP_011531158 (OMIM: 150390) PREDICTED: latent-tran (1682) 5517 670.0 3.8e-191
XP_011531159 (OMIM: 150390) PREDICTED: latent-tran (1680) 4520 551.7 1.6e-155
XP_016859599 (OMIM: 150390) PREDICTED: latent-tran (1639) 4368 533.6 4.4e-150
NP_001159736 (OMIM: 150390) latent-transforming gr (1353) 3802 466.3 6.5e-130
XP_016859598 (OMIM: 150390) PREDICTED: latent-tran (1679) 3802 466.4 7.5e-130
XP_011531163 (OMIM: 150390) PREDICTED: latent-tran (1632) 3585 440.6 4.2e-122
XP_011531164 (OMIM: 150390) PREDICTED: latent-tran (1248) 3574 439.2 8.6e-122
XP_011525685 (OMIM: 604710,613177) PREDICTED: late (1522) 2179 273.7 7.1e-72
XP_011525687 (OMIM: 604710,613177) PREDICTED: late (1478) 2032 256.2 1.3e-66
XP_011525688 (OMIM: 604710,613177) PREDICTED: late (1436) 2017 254.4 4.2e-66
NP_066548 (OMIM: 601216,602090,613097) latent-tran (1256) 1996 251.9 2.2e-65
XP_016882843 (OMIM: 604710,613177) PREDICTED: late (1438) 1990 251.2 3.9e-65
NP_001123616 (OMIM: 601216,602090,613097) latent-t (1303) 1978 249.8 9.7e-65
XP_011525686 (OMIM: 604710,613177) PREDICTED: late (1480) 1965 248.3 3.1e-64
XP_011525680 (OMIM: 604710,613177) PREDICTED: late (1611) 1820 231.1 5e-59
NP_000419 (OMIM: 251750,600975,602091,613086,61481 (1821) 1780 226.4 1.5e-57
XP_011535067 (OMIM: 251750,600975,602091,613086,61 (1694) 1753 223.2 1.3e-56
NP_001157738 (OMIM: 601216,602090,613097) latent-t (1139) 1719 219.0 1.6e-55
XP_011543335 (OMIM: 601216,602090,613097) PREDICTE (1265) 1592 203.9 5.9e-51
XP_011543334 (OMIM: 601216,602090,613097) PREDICTE (1312) 1574 201.8 2.7e-50
NP_000129 (OMIM: 102370,129600,134797,154700,18490 (2871) 1172 154.4 1.1e-35
XP_016882864 (OMIM: 608529) PREDICTED: fibrillin-3 (2768) 1170 154.1 1.3e-35
XP_016864717 (OMIM: 121050,612570,616118) PREDICTE (2861) 1169 154.0 1.4e-35
NP_001990 (OMIM: 121050,612570,616118) fibrillin-2 (2912) 1169 154.0 1.4e-35
XP_016882866 (OMIM: 608529) PREDICTED: fibrillin-3 (1948) 1138 150.2 1.4e-34
XP_016882865 (OMIM: 608529) PREDICTED: fibrillin-3 (2766) 1138 150.3 1.8e-34
XP_016882863 (OMIM: 608529) PREDICTED: fibrillin-3 (2777) 1138 150.3 1.8e-34
XP_016882862 (OMIM: 608529) PREDICTED: fibrillin-3 (2789) 1138 150.3 1.8e-34
NP_115823 (OMIM: 608529) fibrillin-3 precursor [Ho (2809) 1138 150.3 1.8e-34
NP_001308360 (OMIM: 608529) fibrillin-3 precursor (2809) 1138 150.3 1.8e-34
XP_016882861 (OMIM: 608529) PREDICTED: fibrillin-3 (2809) 1138 150.3 1.8e-34
XP_016882868 (OMIM: 608529) PREDICTED: fibrillin-3 (2851) 1138 150.3 1.8e-34
XP_016882867 (OMIM: 608529) PREDICTED: fibrillin-3 (1595) 1132 149.4 1.9e-34
XP_011508340 (OMIM: 603075,608548) PREDICTED: hemi (5518) 858 117.4 2.9e-24
XP_016868907 (OMIM: 602108) PREDICTED: matrilin-2 ( 799) 799 109.6 9.4e-23
XP_005250977 (OMIM: 602108) PREDICTED: matrilin-2 ( 818) 799 109.6 9.5e-23
NP_085072 (OMIM: 602108) matrilin-2 isoform b prec ( 937) 799 109.7 1.1e-22
NP_002371 (OMIM: 602108) matrilin-2 isoform a prec ( 956) 799 109.7 1.1e-22
>>NP_001159737 (OMIM: 150390) latent-transforming growth (1342 aa)
initn: 9897 init1: 9897 opt: 9897 Z-score: 6364.3 bits: 1190.0 E(85289): 0
Smith-Waterman score: 9897; 100.0% identity (100.0% similar) in 1342 aa overlap (1-1342:1-1342)
10 20 30 40 50 60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB3 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
1270 1280 1290 1300 1310 1320
1330 1340
pF1KB3 DKPNYCTPLNTALNLEKDSDLE
::::::::::::::::::::::
NP_001 DKPNYCTPLNTALNLEKDSDLE
1330 1340
>>XP_005264374 (OMIM: 150390) PREDICTED: latent-transfor (1668 aa)
initn: 9772 init1: 9772 opt: 9772 Z-score: 6282.8 bits: 1175.2 E(85289): 0
Smith-Waterman score: 9772; 99.7% identity (99.9% similar) in 1327 aa overlap (16-1342:342-1668)
10 20 30 40
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQ
:. .::::::::::::::::::::::::::
XP_005 KYFPAQKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQ
320 330 340 350 360 370
50 60 70 80 90 100
pF1KB3 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
380 390 400 410 420 430
110 120 130 140 150 160
pF1KB3 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
440 450 460 470 480 490
170 180 190 200 210 220
pF1KB3 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
500 510 520 530 540 550
230 240 250 260 270 280
pF1KB3 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
560 570 580 590 600 610
290 300 310 320 330 340
pF1KB3 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
620 630 640 650 660 670
350 360 370 380 390 400
pF1KB3 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
680 690 700 710 720 730
410 420 430 440 450 460
pF1KB3 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEK
740 750 760 770 780 790
470 480 490 500 510 520
pF1KB3 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
800 810 820 830 840 850
530 540 550 560 570 580
pF1KB3 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP
860 870 880 890 900 910
590 600 610 620 630 640
pF1KB3 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP
920 930 940 950 960 970
650 660 670 680 690 700
pF1KB3 CTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ
980 990 1000 1010 1020 1030
710 720 730 740 750 760
pF1KB3 QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQC
1040 1050 1060 1070 1080 1090
770 780 790 800 810 820
pF1KB3 VCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDIN
1100 1110 1120 1130 1140 1150
830 840 850 860 870 880
pF1KB3 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTA
1160 1170 1180 1190 1200 1210
890 900 910 920 930 940
pF1KB3 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT
1220 1230 1240 1250 1260 1270
950 960 970 980 990 1000
pF1KB3 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_005 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNC
1280 1290 1300 1310 1320 1330
1010 1020 1030 1040 1050 1060
pF1KB3 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
1340 1350 1360 1370 1380 1390
1070 1080 1090 1100 1110 1120
pF1KB3 RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEK
1400 1410 1420 1430 1440 1450
1130 1140 1150 1160 1170 1180
pF1KB3 RCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCAL
1460 1470 1480 1490 1500 1510
1190 1200 1210 1220 1230 1240
pF1KB3 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
1520 1530 1540 1550 1560 1570
1250 1260 1270 1280 1290 1300
pF1KB3 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINT
1580 1590 1600 1610 1620 1630
1310 1320 1330 1340
pF1KB3 DGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
:::::::::::::::::::::::::::::::::::::
XP_005 DGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
1640 1650 1660
>>XP_011531161 (OMIM: 150390) PREDICTED: latent-transfor (1669 aa)
initn: 6585 init1: 6585 opt: 9759 Z-score: 6274.5 bits: 1173.7 E(85289): 0
Smith-Waterman score: 9759; 99.5% identity (99.8% similar) in 1328 aa overlap (16-1342:342-1669)
10 20 30 40
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQ
:. .::::::::::::::::::::::::::
XP_011 KYFPAQKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQ
320 330 340 350 360 370
50 60 70 80 90 100
pF1KB3 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
380 390 400 410 420 430
110 120 130 140 150 160
pF1KB3 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
440 450 460 470 480 490
170 180 190 200 210 220
pF1KB3 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
500 510 520 530 540 550
230 240 250 260 270 280
pF1KB3 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
560 570 580 590 600 610
290 300 310 320 330 340
pF1KB3 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
620 630 640 650 660 670
350 360 370 380 390 400
pF1KB3 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
680 690 700 710 720 730
410 420 430 440 450 460
pF1KB3 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFP-VVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::: .:::
XP_011 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIE
740 750 760 770 780 790
470 480 490 500 510 520
pF1KB3 KTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEG
800 810 820 830 840 850
530 540 550 560 570 580
pF1KB3 YRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLR
860 870 880 890 900 910
590 600 610 620 630 640
pF1KB3 PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCV
920 930 940 950 960 970
650 660 670 680 690 700
pF1KB3 PCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDEC
980 990 1000 1010 1020 1030
710 720 730 740 750 760
pF1KB3 QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ
1040 1050 1060 1070 1080 1090
770 780 790 800 810 820
pF1KB3 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDI
1100 1110 1120 1130 1140 1150
830 840 850 860 870 880
pF1KB3 NECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNT
1160 1170 1180 1190 1200 1210
890 900 910 920 930 940
pF1KB3 AGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPM
1220 1230 1240 1250 1260 1270
950 960 970 980 990 1000
pF1KB3 TGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_011 TGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDN
1280 1290 1300 1310 1320 1330
1010 1020 1030 1040 1050 1060
pF1KB3 CEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLN
1340 1350 1360 1370 1380 1390
1070 1080 1090 1100 1110 1120
pF1KB3 TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASE
1400 1410 1420 1430 1440 1450
1130 1140 1150 1160 1170 1180
pF1KB3 KRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCA
1460 1470 1480 1490 1500 1510
1190 1200 1210 1220 1230 1240
pF1KB3 LCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAE
1520 1530 1540 1550 1560 1570
1250 1260 1270 1280 1290 1300
pF1KB3 ECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCIN
1580 1590 1600 1610 1620 1630
1310 1320 1330 1340
pF1KB3 TDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
::::::::::::::::::::::::::::::::::::::
XP_011 TDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
1640 1650 1660
>>NP_000618 (OMIM: 150390) latent-transforming growth fa (1395 aa)
initn: 7026 init1: 7026 opt: 7097 Z-score: 4567.4 bits: 857.5 E(85289): 0
Smith-Waterman score: 9639; 96.1% identity (96.1% similar) in 1374 aa overlap (22-1342:22-1395)
10 20 30 40 50 60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
:::::::::::::::::::::::::::::::::::::::
NP_000 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
310 320 330 340 350 360
370 380 390
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA-----------------------
:::::::::::::::::::::::::::::::::::::
NP_000 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPI
370 380 390 400 410 420
400 410 420
pF1KB3 ------------------------------KEEPVEALTFSREHGPGVAEPEVATAPPEK
::::::::::::::::::::::::::::::
NP_000 HHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEK
430 440 450 460 470 480
430 440 450 460 470 480
pF1KB3 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVI
490 500 510 520 530 540
490 500 510 520 530 540
pF1KB3 APTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 APTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC
550 560 570 580 590 600
550 560 570 580 590 600
pF1KB3 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
610 620 630 640 650 660
610 620 630 640 650 660
pF1KB3 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN
670 680 690 700 710 720
670 680 690 700 710 720
pF1KB3 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
730 740 750 760 770 780
730 740 750 760 770 780
pF1KB3 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
790 800 810 820 830 840
790 800 810 820 830 840
pF1KB3 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH
850 860 870 880 890 900
850 860 870 880 890 900
pF1KB3 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
910 920 930 940 950 960
910 920 930 940 950 960
pF1KB3 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KB3 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KB3 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KB3 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KB3 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KB3 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KB3 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT
1330 1340 1350 1360 1370 1380
1330 1340
pF1KB3 PLNTALNLEKDSDLE
:::::::::::::::
NP_000 PLNTALNLEKDSDLE
1390
>>NP_996826 (OMIM: 150390) latent-transforming growth fa (1721 aa)
initn: 7026 init1: 7026 opt: 7097 Z-score: 4566.3 bits: 857.6 E(85289): 0
Smith-Waterman score: 9639; 96.1% identity (96.1% similar) in 1374 aa overlap (22-1342:348-1721)
10 20 30 40 50
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKG
::::::::::::::::::::::::::::::
NP_996 KGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKG
320 330 340 350 360 370
60 70 80 90 100 110
pF1KB3 NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGA
380 390 400 410 420 430
120 130 140 150 160 170
pF1KB3 SVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 SVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQI
440 450 460 470 480 490
180 190 200 210 220 230
pF1KB3 HQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 HQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG
500 510 520 530 540 550
240 250 260 270 280 290
pF1KB3 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK
560 570 580 590 600 610
300 310 320 330 340 350
pF1KB3 RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG
620 630 640 650 660 670
360 370 380 390
pF1KB3 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA--------------
::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTV
680 690 700 710 720 730
400 410
pF1KB3 ---------------------------------------KEEPVEALTFSREHGPGVAEP
:::::::::::::::::::::
NP_996 SGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEP
740 750 760 770 780 790
420 430 440 450 460 470
pF1KB3 EVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 EVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEA
800 810 820 830 840 850
480 490 500 510 520 530
pF1KB3 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
860 870 880 890 900 910
540 550 560 570 580 590
pF1KB3 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
920 930 940 950 960 970
600 610 620 630 640 650
pF1KB3 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
980 990 1000 1010 1020 1030
660 670 680 690 700 710
pF1KB3 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
1040 1050 1060 1070 1080 1090
720 730 740 750 760 770
pF1KB3 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
1100 1110 1120 1130 1140 1150
780 790 800 810 820 830
pF1KB3 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
1160 1170 1180 1190 1200 1210
840 850 860 870 880 890
pF1KB3 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
1220 1230 1240 1250 1260 1270
900 910 920 930 940 950
pF1KB3 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
1280 1290 1300 1310 1320 1330
960 970 980 990 1000 1010
pF1KB3 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEF
1340 1350 1360 1370 1380 1390
1020 1030 1040 1050 1060 1070
pF1KB3 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
1400 1410 1420 1430 1440 1450
1080 1090 1100 1110 1120 1130
pF1KB3 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
1460 1470 1480 1490 1500 1510
1140 1150 1160 1170 1180 1190
pF1KB3 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
1520 1530 1540 1550 1560 1570
1200 1210 1220 1230 1240 1250
pF1KB3 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
1580 1590 1600 1610 1620 1630
1260 1270 1280 1290 1300 1310
pF1KB3 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
1640 1650 1660 1670 1680 1690
1320 1330 1340
pF1KB3 PSDKPNYCTPLNTALNLEKDSDLE
::::::::::::::::::::::::
NP_996 PSDKPNYCTPLNTALNLEKDSDLE
1700 1710 1720
>>XP_011531162 (OMIM: 150390) PREDICTED: latent-transfor (1666 aa)
initn: 8948 init1: 6585 opt: 7080 Z-score: 4555.5 bits: 855.6 E(85289): 0
Smith-Waterman score: 9264; 95.7% identity (95.9% similar) in 1322 aa overlap (75-1342:345-1666)
50 60 70 80 90 100
pF1KB3 QNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLC
.:::::::::::::::::::::::::::::
XP_011 PAQKGISGEQSTEGSFPLRYVQDQVAAPFQLICHLPCMNGGQCSSRDKCQCPPNFTGKLC
320 330 340 350 360 370
110 120 130 140 150 160
pF1KB3 QIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHP
380 390 400 410 420 430
170 180 190 200 210 220
pF1KB3 PEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPV
440 450 460 470 480 490
230 240 250 260 270 280
pF1KB3 AAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMM
500 510 520 530 540 550
290 300 310 320 330 340
pF1KB3 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP
560 570 580 590 600 610
350 360 370 380 390
pF1KB3 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICP
620 630 640 650 660 670
400 410
pF1KB3 ----------------------------------------------KEEPVEALTFSREH
::::::::::::::
XP_011 GGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREH
680 690 700 710 720 730
420 430 440 450 460 470
pF1KB3 GPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFP-VVIEKTSPPV
::::::::::::::::::::::::::::::::::::::::::::::::: .:::::::::
XP_011 GPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPV
740 750 760 770 780 790
480 490 500 510 520 530
pF1KB3 PVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQ
800 810 820 830 840 850
540 550 560 570 580 590
pF1KB3 QRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGE
860 870 880 890 900 910
600 610 620 630 640 650
pF1KB3 GHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGF
920 930 940 950 960 970
660 670 680 690 700 710
pF1KB3 RGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLC
980 990 1000 1010 1020 1030
720 730 740 750 760 770
pF1KB3 VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQG
1040 1050 1060 1070 1080 1090
780 790 800 810 820 830
pF1KB3 YRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHP
1100 1110 1120 1130 1140 1150
840 850 860 870 880 890
pF1KB3 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC
1160 1170 1180 1190 1200 1210
900 910 920 930 940 950
pF1KB3 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRS
1220 1230 1240 1250 1260 1270
960 970 980 990 1000 1010
pF1KB3 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPC
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
XP_011 RTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPC
1280 1290 1300 1310 1320 1330
1020 1030 1040 1050 1060 1070
pF1KB3 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYE
1340 1350 1360 1370 1380 1390
1080 1090 1100 1110 1120 1130
pF1KB3 CYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRP
1400 1410 1420 1430 1440 1450
1140 1150 1160 1170 1180 1190
pF1KB3 AESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKD
1460 1470 1480 1490 1500 1510
1200 1210 1220 1230 1240 1250
pF1KB3 SDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILN
1520 1530 1540 1550 1560 1570
1260 1270 1280 1290 1300 1310
pF1KB3 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYK
1580 1590 1600 1610 1620 1630
1320 1330 1340
pF1KB3 CLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
::::::::::::::::::::::::::::::::
XP_011 CLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
1640 1650 1660
>>XP_011531155 (OMIM: 150390) PREDICTED: latent-transfor (1722 aa)
initn: 9327 init1: 6585 opt: 7080 Z-score: 4555.4 bits: 855.6 E(85289): 0
Smith-Waterman score: 9611; 95.9% identity (96.1% similar) in 1374 aa overlap (23-1342:349-1722)
10 20 30 40 50
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGN
::::::::::::::::::::::::::::::
XP_011 GISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGN
320 330 340 350 360 370
60 70 80 90 100 110
pF1KB3 TTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGAS
380 390 400 410 420 430
120 130 140 150 160 170
pF1KB3 VPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIH
440 450 460 470 480 490
180 190 200 210 220 230
pF1KB3 QVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGR
500 510 520 530 540 550
240 250 260 270 280 290
pF1KB3 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKR
560 570 580 590 600 610
300 310 320 330 340 350
pF1KB3 VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGP
620 630 640 650 660 670
360 370 380 390
pF1KB3 CYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVS
680 690 700 710 720 730
400 410
pF1KB3 --------------------------------------KEEPVEALTFSREHGPGVAEPE
::::::::::::::::::::::
XP_011 GVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPE
740 750 760 770 780 790
420 430 440 450 460 470
pF1KB3 VATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFP-VVIEKTSPPVPVEVAPEA
::::::::::::::::::::::::::::::::::::::::: .:::::::::::::::::
XP_011 VATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEA
800 810 820 830 840 850
480 490 500 510 520 530
pF1KB3 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
860 870 880 890 900 910
540 550 560 570 580 590
pF1KB3 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
920 930 940 950 960 970
600 610 620 630 640 650
pF1KB3 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
980 990 1000 1010 1020 1030
660 670 680 690 700 710
pF1KB3 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
1040 1050 1060 1070 1080 1090
720 730 740 750 760 770
pF1KB3 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
1100 1110 1120 1130 1140 1150
780 790 800 810 820 830
pF1KB3 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
1160 1170 1180 1190 1200 1210
840 850 860 870 880 890
pF1KB3 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
1220 1230 1240 1250 1260 1270
900 910 920 930 940 950
pF1KB3 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
1280 1290 1300 1310 1320 1330
960 970 980 990 1000 1010
pF1KB3 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEF
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
XP_011 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEF
1340 1350 1360 1370 1380 1390
1020 1030 1040 1050 1060 1070
pF1KB3 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
1400 1410 1420 1430 1440 1450
1080 1090 1100 1110 1120 1130
pF1KB3 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
1460 1470 1480 1490 1500 1510
1140 1150 1160 1170 1180 1190
pF1KB3 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
1520 1530 1540 1550 1560 1570
1200 1210 1220 1230 1240 1250
pF1KB3 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
1580 1590 1600 1610 1620 1630
1260 1270 1280 1290 1300 1310
pF1KB3 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
1640 1650 1660 1670 1680 1690
1320 1330 1340
pF1KB3 PSDKPNYCTPLNTALNLEKDSDLE
::::::::::::::::::::::::
XP_011 PSDKPNYCTPLNTALNLEKDSDLE
1700 1710 1720
>>XP_011531157 (OMIM: 150390) PREDICTED: latent-transfor (1720 aa)
initn: 9323 init1: 6581 opt: 7075 Z-score: 4552.1 bits: 855.0 E(85289): 0
Smith-Waterman score: 9624; 96.0% identity (96.1% similar) in 1375 aa overlap (21-1342:347-1720)
10 20 30 40 50
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEK
::::::::::::::::::::::::::::::
XP_011 QKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEK
320 330 340 350 360 370
60 70 80 90 100 110
pF1KB3 GNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHG
380 390 400 410 420 430
120 130 140 150 160 170
pF1KB3 ASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQ
440 450 460 470 480 490
180 190 200 210 220 230
pF1KB3 IHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQL
500 510 520 530 540 550
240 250 260 270 280 290
pF1KB3 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGY
560 570 580 590 600 610
300 310 320 330 340 350
pF1KB3 KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEK
620 630 640 650 660 670
360 370 380 390
pF1KB3 GPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYT
680 690 700 710 720 730
400 410
pF1KB3 ----------------------------------------KEEPVEALTFSREHGPGVAE
::::::::::::::::::::
XP_011 VSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAE
740 750 760 770 780 790
420 430 440 450 460 470
pF1KB3 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPE
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_011 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPV-IEKTSPPVPVEVAPE
800 810 820 830 840 850
480 490 500 510 520 530
pF1KB3 ASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDI
860 870 880 890 900 910
540 550 560 570 580 590
pF1KB3 DECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV
920 930 940 950 960 970
600 610 620 630 640 650
pF1KB3 GAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQC
980 990 1000 1010 1020 1030
660 670 680 690 700 710
pF1KB3 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKN
1040 1050 1060 1070 1080 1090
720 730 740 750 760 770
pF1KB3 TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLG
1100 1110 1120 1130 1140 1150
780 790 800 810 820 830
pF1KB3 DHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQG
1160 1170 1180 1190 1200 1210
840 850 860 870 880 890
pF1KB3 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQ
1220 1230 1240 1250 1260 1270
900 910 920 930 940 950
pF1KB3 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLD
1280 1290 1300 1310 1320 1330
960 970 980 990 1000 1010
pF1KB3 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAE
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_011 VDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAE
1340 1350 1360 1370 1380 1390
1020 1030 1040 1050 1060 1070
pF1KB3 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
1400 1410 1420 1430 1440 1450
1080 1090 1100 1110 1120 1130
pF1KB3 YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI
1460 1470 1480 1490 1500 1510
1140 1150 1160 1170 1180 1190
pF1KB3 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQL
1520 1530 1540 1550 1560 1570
1200 1210 1220 1230 1240 1250
pF1KB3 CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC
1580 1590 1600 1610 1620 1630
1260 1270 1280 1290 1300 1310
pF1KB3 VRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY
1640 1650 1660 1670 1680 1690
1320 1330 1340
pF1KB3 VPSDKPNYCTPLNTALNLEKDSDLE
:::::::::::::::::::::::::
XP_011 VPSDKPNYCTPLNTALNLEKDSDLE
1700 1710 1720
>>NP_001159738 (OMIM: 150390) latent-transforming growth (1300 aa)
initn: 7334 init1: 6455 opt: 6602 Z-score: 4250.2 bits: 798.7 E(85289): 0
Smith-Waterman score: 9476; 96.9% identity (96.9% similar) in 1342 aa overlap (1-1342:1-1300)
10 20 30 40 50 60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ
:::::::::::::::::::::::::
NP_001 NTEGSFHCVCQQGFSISADGRTCED-----------------------------------
850 860
910 920 930 940 950 960
pF1KB3 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
870 880 890 900 910
970 980 990 1000 1010 1020
pF1KB3 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KB3 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KB3 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KB3 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KB3 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KB3 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
1220 1230 1240 1250 1260 1270
1330 1340
pF1KB3 DKPNYCTPLNTALNLEKDSDLE
::::::::::::::::::::::
NP_001 DKPNYCTPLNTALNLEKDSDLE
1280 1290 1300
>>XP_005264375 (OMIM: 150390) PREDICTED: latent-transfor (1626 aa)
initn: 7204 init1: 6325 opt: 6482 Z-score: 4172.0 bits: 784.6 E(85289): 0
Smith-Waterman score: 9351; 96.5% identity (96.8% similar) in 1327 aa overlap (16-1342:342-1626)
10 20 30 40
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQ
:. .::::::::::::::::::::::::::
XP_005 KYFPAQKGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQ
320 330 340 350 360 370
50 60 70 80 90 100
pF1KB3 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQ
380 390 400 410 420 430
110 120 130 140 150 160
pF1KB3 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPP
440 450 460 470 480 490
170 180 190 200 210 220
pF1KB3 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVA
500 510 520 530 540 550
230 240 250 260 270 280
pF1KB3 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME
560 570 580 590 600 610
290 300 310 320 330 340
pF1KB3 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPV
620 630 640 650 660 670
350 360 370 380 390 400
pF1KB3 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEAL
680 690 700 710 720 730
410 420 430 440 450 460
pF1KB3 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEK
740 750 760 770 780 790
470 480 490 500 510 520
pF1KB3 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
800 810 820 830 840 850
530 540 550 560 570 580
pF1KB3 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP
860 870 880 890 900 910
590 600 610 620 630 640
pF1KB3 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVP
920 930 940 950 960 970
650 660 670 680 690 700
pF1KB3 CTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ
980 990 1000 1010 1020 1030
710 720 730 740 750 760
pF1KB3 QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQC
1040 1050 1060 1070 1080 1090
770 780 790 800 810 820
pF1KB3 VCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDIN
1100 1110 1120 1130 1140 1150
830 840 850 860 870 880
pF1KB3 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTA
::::::::::::::::::::::::::::::::::::::::
XP_005 ECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCED--------------------
1160 1170 1180 1190
890 900 910 920 930 940
pF1KB3 GSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT
::::::::::::::::::::::::::::::::::::::
XP_005 ----------------------VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMT
1200 1210 1220
950 960 970 980 990 1000
pF1KB3 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNC
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_005 GQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNC
1230 1240 1250 1260 1270 1280
1010 1020 1030 1040 1050 1060
pF1KB3 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNT
1290 1300 1310 1320 1330 1340
1070 1080 1090 1100 1110 1120
pF1KB3 RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEK
1350 1360 1370 1380 1390 1400
1130 1140 1150 1160 1170 1180
pF1KB3 RCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCAL
1410 1420 1430 1440 1450 1460
1190 1200 1210 1220 1230 1240
pF1KB3 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEE
1470 1480 1490 1500 1510 1520
1250 1260 1270 1280 1290 1300
pF1KB3 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINT
1530 1540 1550 1560 1570 1580
1310 1320 1330 1340
pF1KB3 DGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
:::::::::::::::::::::::::::::::::::::
XP_005 DGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
1590 1600 1610 1620
1342 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:15:23 2016 done: Thu Nov 3 12:15:25 2016
Total Scan time: 16.510 Total Display time: 0.670
Function used was FASTA [36.3.4 Apr, 2011]