Result of FASTA (ccds) for
pF1KB3048
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3048, 1342 aa
1>>>pF1KB3048 1342 - 1342 aa - 1342 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2458+/-0.00121; mu= 10.2369+/- 0.072
mean_var=224.4839+/-44.242, 0's: 0 Z-trim(109.1): 191 B-trim: 2 in 1/53
Lambda= 0.085602
statistics sampled from 10485 (10681) to 10485 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.328), width: 16
Scan time: 5.360
The best scores are: opt bits E(32554)
CCDS54345.1 LTBP1 gene_id:4052|Hs108|chr2 (1342) 9892 1236.3 0
CCDS33178.2 LTBP1 gene_id:4052|Hs108|chr2 (1395) 7092 890.5 0
CCDS33177.2 LTBP1 gene_id:4052|Hs108|chr2 (1721) 7092 890.6 0
CCDS54344.1 LTBP1 gene_id:4052|Hs108|chr2 (1353) 3802 484.2 1.1e-135
CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11 (1256) 1996 261.1 1.4e-68
CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11 (1303) 1978 258.9 6.6e-68
CCDS9831.1 LTBP2 gene_id:4053|Hs108|chr14 (1821) 1780 234.6 1.9e-60
CCDS32232.1 FBN1 gene_id:2200|Hs108|chr15 (2871) 1172 159.7 1.1e-37
CCDS34222.1 FBN2 gene_id:2201|Hs108|chr5 (2912) 1169 159.3 1.4e-37
CCDS12196.1 FBN3 gene_id:84467|Hs108|chr19 (2809) 1138 155.5 1.9e-36
CCDS55265.1 MATN2 gene_id:4147|Hs108|chr8 ( 937) 799 113.1 3.6e-24
CCDS55264.1 MATN2 gene_id:4147|Hs108|chr8 ( 956) 799 113.2 3.6e-24
CCDS74370.1 LTBP4 gene_id:8425|Hs108|chr19 (1557) 793 112.6 8.5e-24
CCDS74368.1 LTBP4 gene_id:8425|Hs108|chr19 (1587) 793 112.6 8.6e-24
CCDS74369.1 LTBP4 gene_id:8425|Hs108|chr19 (1624) 793 112.6 8.8e-24
CCDS83309.1 MATN2 gene_id:4147|Hs108|chr8 ( 915) 777 110.4 2.3e-23
CCDS30956.1 HMCN1 gene_id:83872|Hs108|chr1 (5635) 783 111.9 5e-23
CCDS14048.1 SCUBE1 gene_id:80274|Hs108|chr22 ( 988) 759 108.2 1.1e-22
CCDS34420.1 NOTCH4 gene_id:4855|Hs108|chr6 (2003) 618 91.1 3.3e-17
CCDS9898.1 FBLN5 gene_id:10516|Hs108|chr14 ( 448) 595 87.6 8.1e-17
CCDS1857.1 EFEMP1 gene_id:2202|Hs108|chr2 ( 493) 585 86.4 2e-16
CCDS41237.1 MEGF6 gene_id:1953|Hs108|chr1 (1541) 588 87.3 3.5e-16
CCDS9999.1 JAG2 gene_id:3714|Hs108|chr14 (1200) 562 84.0 2.7e-15
CCDS8116.1 EFEMP2 gene_id:30008|Hs108|chr11 ( 443) 539 80.7 9.7e-15
CCDS13149.1 CD93 gene_id:22918|Hs108|chr20 ( 652) 540 81.0 1.2e-14
CCDS9998.1 JAG2 gene_id:3714|Hs108|chr14 (1238) 529 79.9 4.7e-14
CCDS12326.1 NOTCH3 gene_id:4854|Hs108|chr19 (2321) 531 80.4 6.2e-14
CCDS44864.1 NELL2 gene_id:4753|Hs108|chr12 ( 815) 503 76.5 3.3e-13
CCDS8746.1 NELL2 gene_id:4753|Hs108|chr12 ( 816) 503 76.5 3.3e-13
CCDS53781.1 NELL2 gene_id:4753|Hs108|chr12 ( 839) 503 76.5 3.3e-13
CCDS44863.1 NELL2 gene_id:4753|Hs108|chr12 ( 866) 503 76.6 3.4e-13
CCDS908.1 NOTCH2 gene_id:4853|Hs108|chr1 (2471) 510 77.9 3.9e-13
CCDS43028.1 FBLN1 gene_id:2192|Hs108|chr22 ( 566) 496 75.5 4.6e-13
CCDS14068.1 FBLN1 gene_id:2192|Hs108|chr22 ( 601) 496 75.5 4.8e-13
CCDS14069.1 FBLN1 gene_id:2192|Hs108|chr22 ( 683) 496 75.6 5.2e-13
CCDS14067.1 FBLN1 gene_id:2192|Hs108|chr22 ( 703) 496 75.6 5.4e-13
CCDS46762.1 FBLN2 gene_id:2199|Hs108|chr3 (1184) 496 75.8 7.7e-13
CCDS53599.1 SCUBE2 gene_id:57758|Hs108|chr11 ( 807) 483 74.1 1.8e-12
CCDS58644.1 ADGRE1 gene_id:2015|Hs108|chr19 ( 821) 483 74.1 1.8e-12
CCDS46761.1 FBLN2 gene_id:2199|Hs108|chr3 (1231) 486 74.6 1.9e-12
CCDS12175.1 ADGRE1 gene_id:2015|Hs108|chr19 ( 886) 483 74.1 1.9e-12
CCDS7797.2 SCUBE2 gene_id:57758|Hs108|chr11 ( 971) 483 74.1 2e-12
CCDS81553.1 SCUBE2 gene_id:57758|Hs108|chr11 ( 999) 483 74.1 2.1e-12
CCDS7113.1 CUBN gene_id:8029|Hs108|chr10 (3623) 482 74.6 5.6e-12
CCDS4800.1 SCUBE3 gene_id:222663|Hs108|chr6 ( 993) 464 71.8 1.1e-11
CCDS58651.1 LDLR gene_id:3949|Hs108|chr19 ( 858) 443 69.1 5.8e-11
CCDS12254.1 LDLR gene_id:3949|Hs108|chr19 ( 860) 443 69.1 5.8e-11
CCDS58645.1 ADGRE1 gene_id:2015|Hs108|chr19 ( 867) 443 69.1 5.8e-11
CCDS34979.1 VLDLR gene_id:7436|Hs108|chr9 ( 845) 439 68.6 8e-11
CCDS45072.1 GAS6 gene_id:2621|Hs108|chr13 ( 678) 437 68.3 8.1e-11
>>CCDS54345.1 LTBP1 gene_id:4052|Hs108|chr2 (1342 aa)
initn: 9892 init1: 9892 opt: 9892 Z-score: 6614.5 bits: 1236.3 E(32554): 0
Smith-Waterman score: 9892; 99.9% identity (100.0% similar) in 1342 aa overlap (1-1342:1-1342)
10 20 30 40 50 60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHC
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB3 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB3 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB3 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
CCDS54 DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB3 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB3 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB3 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB3 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB3 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPS
1270 1280 1290 1300 1310 1320
1330 1340
pF1KB3 DKPNYCTPLNTALNLEKDSDLE
::::::::::::::::::::::
CCDS54 DKPNYCTPLNTALNLEKDSDLE
1330 1340
>>CCDS33178.2 LTBP1 gene_id:4052|Hs108|chr2 (1395 aa)
initn: 7021 init1: 7021 opt: 7092 Z-score: 4745.4 bits: 890.5 E(32554): 0
Smith-Waterman score: 9634; 96.1% identity (96.1% similar) in 1374 aa overlap (22-1342:22-1395)
10 20 30 40 50 60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
:::::::::::::::::::::::::::::::::::::::
CCDS33 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
310 320 330 340 350 360
370 380 390
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA-----------------------
:::::::::::::::::::::::::::::::::::::
CCDS33 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPI
370 380 390 400 410 420
400 410 420
pF1KB3 ------------------------------KEEPVEALTFSREHGPGVAEPEVATAPPEK
::::::::::::::::::::::::::::::
CCDS33 HHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEK
430 440 450 460 470 480
430 440 450 460 470 480
pF1KB3 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVI
490 500 510 520 530 540
490 500 510 520 530 540
pF1KB3 APTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 APTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC
550 560 570 580 590 600
550 560 570 580 590 600
pF1KB3 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
610 620 630 640 650 660
610 620 630 640 650 660
pF1KB3 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN
670 680 690 700 710 720
670 680 690 700 710 720
pF1KB3 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
730 740 750 760 770 780
730 740 750 760 770 780
pF1KB3 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
790 800 810 820 830 840
790 800 810 820 830 840
pF1KB3 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH
850 860 870 880 890 900
850 860 870 880 890 900
pF1KB3 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
910 920 930 940 950 960
910 920 930 940 950 960
pF1KB3 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KB3 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
CCDS33 KECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKG
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KB3 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KB3 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KB3 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KB3 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KB3 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT
1330 1340 1350 1360 1370 1380
1330 1340
pF1KB3 PLNTALNLEKDSDLE
:::::::::::::::
CCDS33 PLNTALNLEKDSDLE
1390
>>CCDS33177.2 LTBP1 gene_id:4052|Hs108|chr2 (1721 aa)
initn: 7021 init1: 7021 opt: 7092 Z-score: 4744.3 bits: 890.6 E(32554): 0
Smith-Waterman score: 9634; 96.1% identity (96.1% similar) in 1374 aa overlap (22-1342:348-1721)
10 20 30 40 50
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKG
::::::::::::::::::::::::::::::
CCDS33 KGISGEQSTEGSFPLRYVQDQVAAPFQLSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKG
320 330 340 350 360 370
60 70 80 90 100 110
pF1KB3 NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 NTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGA
380 390 400 410 420 430
120 130 140 150 160 170
pF1KB3 SVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQI
440 450 460 470 480 490
180 190 200 210 220 230
pF1KB3 HQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HQVSRIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLG
500 510 520 530 540 550
240 250 260 270 280 290
pF1KB3 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYK
560 570 580 590 600 610
300 310 320 330 340 350
pF1KB3 RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKG
620 630 640 650 660 670
360 370 380 390
pF1KB3 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA--------------
::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTV
680 690 700 710 720 730
400 410
pF1KB3 ---------------------------------------KEEPVEALTFSREHGPGVAEP
:::::::::::::::::::::
CCDS33 SGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEP
740 750 760 770 780 790
420 430 440 450 460 470
pF1KB3 EVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEA
800 810 820 830 840 850
480 490 500 510 520 530
pF1KB3 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 STSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDID
860 870 880 890 900 910
540 550 560 570 580 590
pF1KB3 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVG
920 930 940 950 960 970
600 610 620 630 640 650
pF1KB3 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AFRCEYCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCL
980 990 1000 1010 1020 1030
660 670 680 690 700 710
pF1KB3 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNT
1040 1050 1060 1070 1080 1090
720 730 740 750 760 770
pF1KB3 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGD
1100 1110 1120 1130 1140 1150
780 790 800 810 820 830
pF1KB3 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGE
1160 1170 1180 1190 1200 1210
840 850 860 870 880 890
pF1KB3 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
1220 1230 1240 1250 1260 1270
900 910 920 930 940 950
pF1KB3 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
1280 1290 1300 1310 1320 1330
960 970 980 990 1000 1010
pF1KB3 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEF
::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::
CCDS33 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEF
1340 1350 1360 1370 1380 1390
1020 1030 1040 1050 1060 1070
pF1KB3 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
1400 1410 1420 1430 1440 1450
1080 1090 1100 1110 1120 1130
pF1KB3 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 YDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIE
1460 1470 1480 1490 1500 1510
1140 1150 1160 1170 1180 1190
pF1KB3 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 ETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC
1520 1530 1540 1550 1560 1570
1200 1210 1220 1230 1240 1250
pF1KB3 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 NIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCV
1580 1590 1600 1610 1620 1630
1260 1270 1280 1290 1300 1310
pF1KB3 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYV
1640 1650 1660 1670 1680 1690
1320 1330 1340
pF1KB3 PSDKPNYCTPLNTALNLEKDSDLE
::::::::::::::::::::::::
CCDS33 PSDKPNYCTPLNTALNLEKDSDLE
1700 1710 1720
>>CCDS54344.1 LTBP1 gene_id:4052|Hs108|chr2 (1353 aa)
initn: 7325 init1: 3584 opt: 3802 Z-score: 2549.8 bits: 484.2 E(32554): 1.1e-135
Smith-Waterman score: 9213; 93.0% identity (93.1% similar) in 1374 aa overlap (22-1342:22-1353)
10 20 30 40 50 60
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
:::::::::::::::::::::::::::::::::::::::
CCDS54 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTTTLISEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 INECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSG
310 320 330 340 350 360
370 380 390
pF1KB3 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTA-----------------------
:::::::::::::::::::::::::::::::::::::
CCDS54 RQCMHPLSVHLTKQLCCCSVGKAWGPHCEKCPLPGTAAFKEICPGGMGYTVSGVHRRRPI
370 380 390 400 410 420
400 410 420
pF1KB3 ------------------------------KEEPVEALTFSREHGPGVAEPEVATAPPEK
::::::::::::::::::::::::::::::
CCDS54 HHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEK
430 440 450 460 470 480
430 440 450 460 470 480
pF1KB3 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVI
490 500 510 520 530 540
490 500 510 520 530 540
pF1KB3 APTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 APTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLC
550 560 570 580 590 600
550 560 570 580 590 600
pF1KB3 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDS
610 620 630 640 650 660
610 620 630 640 650 660
pF1KB3 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPN
670 680 690 700 710 720
670 680 690 700 710 720
pF1KB3 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCG
730 740 750 760 770 780
730 740 750 760 770 780
pF1KB3 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 QGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
790 800 810 820 830 840
790 800 810 820 830 840
pF1KB3 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH
850 860 870 880 890 900
850 860 870 880 890 900
pF1KB3 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
::::::::::::::::::
CCDS54 CVCQQGFSISADGRTCED------------------------------------------
910
910 920 930 940 950 960
pF1KB3 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
920 930 940 950 960 970
970 980 990 1000 1010 1020
pF1KB3 KECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKG
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
CCDS54 KECYYNLNDASLCDNVLAPNVTKQECCCTSGVGWGDNCEIFPCPVLGTAEFTEMCPKGKG
980 990 1000 1010 1020 1030
1030 1040 1050 1060 1070 1080
pF1KB3 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 FVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCF
1040 1050 1060 1070 1080 1090
1090 1100 1110 1120 1130 1140
pF1KB3 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLC
1100 1110 1120 1130 1140 1150
1150 1160 1170 1180 1190 1200
pF1KB3 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQ
1160 1170 1180 1190 1200 1210
1210 1220 1230 1240 1250 1260
pF1KB3 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCD
1220 1230 1240 1250 1260 1270
1270 1280 1290 1300 1310 1320
pF1KB3 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 CFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCT
1280 1290 1300 1310 1320 1330
1330 1340
pF1KB3 PLNTALNLEKDSDLE
:::::::::::::::
CCDS54 PLNTALNLEKDSDLE
1340 1350
>>CCDS8103.1 LTBP3 gene_id:4054|Hs108|chr11 (1256 aa)
initn: 2210 init1: 577 opt: 1996 Z-score: 1344.8 bits: 261.1 E(32554): 1.4e-68
Smith-Waterman score: 3430; 39.1% identity (59.6% similar) in 1387 aa overlap (25-1328:61-1252)
10 20 30 40 50
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTT
:.::::.: ::: :: ::.:..::..:..
CCDS81 LLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB3 TLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGA---
:::.::::..::::...::::.: ::::::::::::..: :::.:::..::.:. ::
CCDS81 TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGG
100 110 120 130 140 150
120 130
pF1KB3 -----------------SVPKLY--------QHS--------QQPGKALGTHVIHSTHTL
..: : .:. . :: . : . :.. .
CCDS81 TGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLV
160 170 180 190 200 210
140 150 160 170 180 190
pF1KB3 PLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQ
:: .: ...:. :: .::..:.::::::::.: ::.. .... : :.:
CCDS81 PLG-PGQISAEVQAPPPVVNVRVHHPPEASVQVH---RIESSNAES---AAPSQHL----
220 230 240 250
200 210 220 230 240 250
pF1KB3 GLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQ-CGKA-LPGLSKQEDCC
:: : :: . : . : ::::::.:. .: ::. ::::.::::::
CCDS81 -LP-------HPKPSHPR------PPTQKP-LGRCFQDTLPKQPCGSNPLPGLTKQEDCC
260 270 280 290 300
260 270 280 290 300
pF1KB3 GTVGTSWGFNKCQKCPK-------KPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGV
:..::.:: .::.:::. ::. . .: ::::.:.: ::::::: . ::
CCDS81 GSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGV
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB3 CPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSV
: .:.:::. :::::.: : . :. ..:. : : :::. :.:::: .::.:::..
CCDS81 CRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKP---EEKSLCFRLVSPEHQCQHPLTT
370 380 390 400 410 420
370 380 390 400 410
pF1KB3 HLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPV-------------EALTFSRE------
.::.:::::::::::: .:..:: ::: . . ..::.. :
CCDS81 RLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLF
430 440 450 460 470 480
420 430 440 450 460
pF1KB3 -HGPGVAEPEVATAPPEKEIPSLDQEKTK-LEPGQP--------QLSPGISTIHLHPQFP
: : .:. : . : : :. . . .: : : .: .: .:
CCDS81 LHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARP-YP
490 500 510 520 530 540
470 480 490 500 510 520
pF1KB3 VVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCI
.: . :::. :. : .. :::::::: .:: .: .::: :.:. : :.:
CCDS81 ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCH
550 560 570 580 590 600
530 540 550 560 570
pF1KB3 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGR--CENTEGSFLCICPAGF--MASEEGTNC
: ::: :.: :::..:: . :. :: : :: ::. : : :. .. : .:
CCDS81 CNPGYRSHPQHRYCVDVNECE--AEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSC
610 620 630 640 650
580 590 600 610 620 630
pF1KB3 IDVDECLRPDVCGEG-HCVNTVGAFRCEYCDSGYRM--TQRGRCEDIDECLNPSTCPDEQ
.:..:: .: .::.: :.: : ..:. : :::. .. ::::::: .::.::: .
CCDS81 VDLNECAKPHLCGDGGFCINFPGHYKCN-CYPGYRLKASRPPVCEDIDECRDPSSCPDGK
660 670 680 690 700 710
640 650 660 670 680 690
pF1KB3 CVNSPGSYQCVPCTEGFRGWNG-QCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRT
: :.:::..:. : :.:. .: : ::.:: : . :. : : :: ::. :.: .::. .
CCDS81 CENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPA
720 730 740 750 760 770
700 710 720 730 740 750
pF1KB3 PDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA
:: . : :.:::. :..: :: :.:: :::.: : .::.:: ...:::::::.
CCDS81 PDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD------
780 790 800 810 820 830
760 770 780 790 800 810
pF1KB3 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDG
: .: .: :::::: ::: : ::.:
CCDS81 ----------FPAAC--------IG------------------GDCINTNGSYRCLCPQG
840 850
820 830 840 850 860 870
pF1KB3 FQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVN
.: .. ::::.:: . :.:: :.: : : .::. :::..::. . :
CCDS81 HRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQD------------
860 870 880 890 900
880 890 900 910 920 930
pF1KB3 NTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFL
.:: ::.::
CCDS81 -----QHG-------------------------------------------CEEVE----
910
940 950 960 970 980 990
pF1KB3 CVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQ
::.. ::::: :..:. .::.::: :::.:
CCDS81 ------------------------------QPHH-KKECYLNFDDTVFCDSVLATNVTQQ
920 930 940
1000 1010 1020 1030 1040 1050
pF1KB3 ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLL
::::. ::::::.:::.:::: ..::: .:: :::.. .. . : ..: :::.:
CCDS81 ECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQ-DNNIVNYGIPAHRDIDECML
950 960 970 980 990
1060 1070 1080 1090 1100 1110
pF1KB3 FGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYN
::.::::.: :.::.:::::::::: ::: :.: :.::: : :.: .: : ::.:.:
CCDS81 FGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYR
1000 1010 1020 1030 1040 1050
1120 1130 1140 1150 1160 1170
pF1KB3 CFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTEC
: :: : . ....:. : :..:.. .:.:: . ... .:. ::.: :. .:
CCDS81 CACTPPAEYSPAQRQCLSP----EEMERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDC
1060 1070 1080 1090 1100 1110
1180 1190 1200 1210 1220 1230
pF1KB3 CCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQ
:: :..:: :: :: . . .. : :.. .. ... : : . : .
CCDS81 CCRQGRGWGAQCRPCPPRGAGSH---C--PTSQSES----NSFWDTSPLLLGKP-P---R
1120 1130 1140 1150 1160
1240 1250 1260 1270 1280 1290
pF1KB3 DRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELN
:. .: :: ...:: : .:::: : .:.: :..::... :::..:: :::
CCDS81 DE--DSSEE-DSDECR----CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELN
1170 1180 1190 1200 1210
1300 1310 1320 1330 1340
pF1KB3 NRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
.: :::. .:.::.::..:.: :.. : . :.:
CCDS81 QRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRRR
1220 1230 1240 1250
>>CCDS44647.1 LTBP3 gene_id:4054|Hs108|chr11 (1303 aa)
initn: 2707 init1: 553 opt: 1978 Z-score: 1332.6 bits: 258.9 E(32554): 6.6e-68
Smith-Waterman score: 3348; 38.0% identity (57.8% similar) in 1430 aa overlap (25-1328:61-1299)
10 20 30 40 50
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNSCEKGNTT
:.::::.: ::: :: ::.:..::..:..
CCDS44 LLLLLGLGGRVEGGPAGERGAGGGGALARERFKVVFAPVICKRTCLKGQCRDSCQQGSNM
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB3 TLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGA---
:::.::::..::::...::::.: ::::::::::::..: :::.:::..::.:. ::
CCDS44 TLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQCLCPPDFTGRFCQVPAGGAGGG
100 110 120 130 140 150
120 130
pF1KB3 -----------------SVPKLY--------QHS--------QQPGKALGTHVIHSTHTL
..: : .:. . :: . : . :.. .
CCDS44 TGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLV
160 170 180 190 200 210
140 150 160 170 180 190
pF1KB3 PLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPGQSQVSYQ
:: .: ...:. :: .::..:.::::::::.: ::.. .... : :.:
CCDS44 PLG-PGQISAEVQAPPPVVNVRVHHPPEASVQVH---RIESSNAES---AAPSQHL----
220 230 240 250
200 210 220 230 240 250
pF1KB3 GLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQ-CGKA-LPGLSKQEDCC
:: : :: . : . : ::::::.:. .: ::. ::::.::::::
CCDS44 -LP-------HPKPSHPR------PPTQKP-LGRCFQDTLPKQPCGSNPLPGLTKQEDCC
260 270 280 290 300
260 270 280 290 300
pF1KB3 GTVGTSWGFNKCQKCPK-------KPSYHGYNQMMECLPGYKRVNNTFCQDINECQLQGV
:..::.:: .::.:::. ::. . .: ::::.:.: ::::::: . ::
CCDS44 GSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGV
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB3 CPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSV
: .:.:::. :::::.: : . :. ..:. : : :::. :.:::: .::.:::..
CCDS44 CRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKP---EEKSLCFRLVSPEHQCQHPLTT
370 380 390 400 410 420
370 380 390 400 410
pF1KB3 HLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPV-------------EALTFSRE------
.::.:::::::::::: .:..:: ::: . . ..::.. :
CCDS44 RLTRQLCCCSVGKAWGARCQRCPTDGTAAFKEICPAGKGYHILTSHQTLTIQGESDFSLF
430 440 450 460 470 480
420 430 440 450 460
pF1KB3 -HGPGVAEPEVATAPPEKEIPSLDQEKTK-LEPGQP--------QLSPGISTIHLHPQFP
: : .:. : . : : :. . . .: : : .: .: .:
CCDS44 LHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARP-YP
490 500 510 520 530 540
470 480 490 500 510 520
pF1KB3 VVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCI
.: . :::. :. : .. :::::::: .:: .: .::: :.:. : :.:
CCDS44 ELISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCH
550 560 570 580 590 600
530 540 550 560 570
pF1KB3 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGR--CENTEGSFLCICPAGF--MASEEGTNC
: ::: :.: :::..:: . :. :: : :: ::. : : :. .. : .:
CCDS44 CNPGYRSHPQHRYCVDVNECE--AEPCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSC
610 620 630 640 650
580 590 600 610 620 630
pF1KB3 IDVDECLRPDVCGEG-HCVNTVGAFRCEYCDSGYRM--TQRGRCEDIDECLNPSTCPDEQ
.:..:: .: .::.: :.: : ..:. : :::. .. ::::::: .::.::: .
CCDS44 VDLNECAKPHLCGDGGFCINFPGHYKCN-CYPGYRLKASRPPVCEDIDECRDPSSCPDGK
660 670 680 690 700 710
640 650 660 670 680 690
pF1KB3 CVNSPGSYQCVPCTEGFRGWNG-QCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRT
: :.:::..:. : :.:. .: : ::.:: : . :. : : :: ::. :.: .::. .
CCDS44 CENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPA
720 730 740 750 760 770
700 710 720 730 740 750
pF1KB3 PDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA
:: . : :.:::. :..: :: :.:: :::.: : .::.:: ...:::::::.
CCDS44 PDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECD------
780 790 800 810 820 830
760 770 780 790 800 810
pF1KB3 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDG
: .: .: :::::: ::: : ::.:
CCDS44 ----------FPAAC--------IG------------------GDCINTNGSYRCLCPQG
840 850
820 830 840 850 860 870
pF1KB3 FQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVN
.: .. ::::.:: . :.:: :.: : : .::. :::..::. . :
CCDS44 HRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQD------------
860 870 880 890 900
880 890 900 910 920 930
pF1KB3 NTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFL
.:: ::.::
CCDS44 -----QHG-------------------------------------------CEEVE----
910
940 950 960 970 980 990
pF1KB3 CVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQ
::.. ::::: :..:. .::.::: :::.:
CCDS44 ------------------------------QPHH-KKECYLNFDDTVFCDSVLATNVTQQ
920 930 940
1000 1010 1020 1030 1040 1050
pF1KB3 ECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLL
::::. ::::::.:::.:::: ..::: .:: :::.. .. . : ..: :::.:
CCDS44 ECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQ-DNNIVNYGIPAHRDIDECML
950 960 970 980 990
1060 1070 1080 1090 1100 1110
pF1KB3 FGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYN
::.::::.: :.::.:::::::::: ::: :.: :.::: : :.: .: : ::.:.:
CCDS44 FGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYR
1000 1010 1020 1030 1040 1050
1120 1130
pF1KB3 CFCTHPMVLDASEKRCIRPAE--------------------------------------S
: :: : . ....:. : :
CCDS44 CACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGR
1060 1070 1080 1090 1100 1110
1140 1150 1160 1170 1180
pF1KB3 NEQIEETDV-----YQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPL
. :. :. . .:.:: . ... .:. ::.: :. .::: :..:: :: ::
CCDS44 DCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPP
1120 1130 1140 1150 1160 1170
1190 1200 1210 1220 1230 1240
pF1KB3 KDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGI
. . .. : :.. .. ... : : . : .:. .: :: ...::
CCDS44 RGAGSH---C--PTSQSES----NSFWDTSPLLLGKP-P---RDE--DSSEE-DSDECR-
1180 1190 1200 1210 1220
1250 1260 1270 1280 1290 1300
pF1KB3 LNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGS
: .:::: : .:.: :..::... :::..:: :::.: :::. .:.::.::
CCDS44 ---CVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGS
1230 1240 1250 1260 1270
1310 1320 1330 1340
pF1KB3 YKCLCLPGYVPSDKPNYCTPLNTALNLEKDSDLE
..:.: :.. : . :.:
CCDS44 FRCVCKAGFARSRPHGACVPQRRR
1280 1290 1300
>>CCDS9831.1 LTBP2 gene_id:4053|Hs108|chr14 (1821 aa)
initn: 1882 init1: 674 opt: 1780 Z-score: 1198.6 bits: 234.6 E(32554): 1.9e-60
Smith-Waterman score: 3810; 42.3% identity (64.5% similar) in 1348 aa overlap (17-1226:342-1662)
10 20 30 40
pF1KB3 MDTKLMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQN
: .... .::.::::.::: ::..: : :
CCDS98 SNALPPGPGLEQRDGTQQAVPLEHPSSPWGLNLTEKIKKIKIVFTPTICKQTCARGHCAN
320 330 340 350 360 370
50 60 70 80 90 100
pF1KB3 SCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQI
:::.:.:::: :..::. : ..::. .:..::.:::.: .::.: :: : :::.:..
CCDS98 SCERGDTTTLYSQGGHGHD--PKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHL
380 390 400 410 420
110 120 130 140 150 160
pF1KB3 PVHGASVPKLYQHSQQPGKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPE
:. . . :. : : . . .:: :::: :.: ..:. :..:..:..::::
CCDS98 PIPQPDREPPGRGSR-PRALLEAPLKQSTFTLPL---SNQLASVN--PSLVKVHIHHPPE
430 440 450 460 470 480
170 180 190 200 210 220
pF1KB3 ASVQIHQVSRIDGPTGQ----KTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVY
::::::::... : . . .. :..: . : . ...: . .. :.
CCDS98 ASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGHSLWDSNNIPARSGEP---PRPL
490 500 510 520 530 540
230 240 250 260 270
pF1KB3 PVAA---KTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHG
: :: . ::::. .:...::.. : :. ::::::.::. :: . : :: .:.
CCDS98 PPAAPRPRGLLGRCYLNTVNGQCANPLLELTTQEDCCGSVGAFWGVTLCAPCPPRPASPV
550 560 570 580 590 600
280 290 300 310 320 330
pF1KB3 Y-NQMMECLPGYKRVNNTFCQDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSS
: ..:: ::::.: : ::::::: :.: ..::.:: ::: :::. :. ::. :
CCDS98 IENGQLECPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSR
610 620 630 640 650 660
340 350 360 370 380 390
pF1KB3 CVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCS-VGKAWGPHCEKCPLPGTA
:: : .:: .: ::: .. : : ::. ..:::.:::: :::::: .:::::::::
CCDS98 CVSDK-AISMLQGLCYRSLGPGT-CTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTE
670 680 690 700 710
400 410 420 430
pF1KB3 KEEPV----EALTFS----REHGPGVAEPEVATAPPEK------EIPSLDQEK-------
. . .. :.. : . : :.: : :. .:. ...
CCDS98 AFREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALPGPAERQPLRVVTD
720 730 740 750 760 770
440 450 460 470 480
pF1KB3 TKLE----PGQPQLSPG-ISTIHLHPQFPVVIEKTSPPVP----VEVAPEASTSSASQVI
: :: : . . . : ..: : :. . :.::.: .:. : : : ..:.
CCDS98 TWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPS-TDVL
780 790 800 810 820 830
490 500 510 520 530 540
pF1KB3 APTQVTEINECTVNP-DICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHL
. .. :..:... ..:: : :.::: : :.: ::.. .: :.: .:: ..
CCDS98 VTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNEC--LRDP
840 850 860 870 880 890
550 560 570 580 590 600
pF1KB3 CS-QGRCENTEGSFLCICPAGFMASEEGTN--CIDVDECLRPDVCGEGHCVNTVGAFRCE
:. .::: : ::. :.: :. . :.. : :..:: .: ::. :.:.:: :...::
CCDS98 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCE
900 910 920 930 940 950
610 620 630 640 650 660
pF1KB3 YCDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC
::.:: :...:.:.::.:: .:.:::: .:::::::: :. : ::.:: .:.:.::.::
CCDS98 -CDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNEC
960 970 980 990 1000 1010
670 680 690 700 710 720
pF1KB3 LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFR
: :.:::.: :.:::::. :::..:: : :.: :.:.::: . : .: : ::::::
CCDS98 LTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFA
1020 1030 1040 1050 1060 1070
730 740 750 760 770 780
pF1KB3 CT-CGQGYQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCV-CDQGYRASGLGDHCE
:. : .:: .. :::.::: .: : : :: :::.: :: ::: : ::: ::
CCDS98 CSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE
1080 1090 1100 1110 1120 1130
790 800 810 820 830 840
pF1KB3 DINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLN
:..:: . .: : :.: ::.:::.: ::.:::: .. .:.:.::: :.:.:::::
CCDS98 DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLN
1140 1150 1160 1170 1180 1190
850 860
pF1KB3 TEGSFHCVCQQGFSISADGRT-----------------------------CE--------
..::: :.: :: .::.: : ::
CCDS98 SHGSFFCLCAPGF-VSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPE
1200 1210 1220 1230 1240 1250
870
pF1KB3 -------------------------------------------------DIDECVNNTVC
:::::.:.:.:
CCDS98 SGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMC
1260 1270 1280 1290 1300 1310
880 890 900 910 920 930
pF1KB3 DSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCA
:::::::: ::::::: :::. .: :::::::::. .::: :.::::::::::.::
CCDS98 GSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLCLCA
1320 1330 1340 1350 1360 1370
940 950 960 970 980 990
pF1KB3 DENQEYSPMTGQCRSR-----TSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTK
.. .::. . :.:: : . .. . : . .:: . . . :..::. :.:.
CCDS98 SDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQ
1380 1390 1400 1410 1420 1430
1000 1010 1020 1030 1040 1050
pF1KB3 QECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECL
:::::.::.::: :.. :: .:::.:.::.:::..:. :.. : : :::::.
CCDS98 AECCCTQGASWGDACDL--CPSEDSAEFSEICPSGKGYIPV-EGAWTFGQTMYTDADECV
1440 1450 1460 1470 1480 1490
1060 1070 1080 1090 1100 1110
pF1KB3 LFGQEICKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSY
.:: .: :: :::: ::: : :. : .:: . .: : ::::: .: .:.:::::::.
CCDS98 IFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDECQD-LACENGECVNTEGSF
1500 1510 1520 1530 1540
1120 1130 1140 1150 1160 1170
pF1KB3 NCFCTHPMVLDASEKRCIRPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTE
.:::. :..:: :..::. . :.:.. . :...:.::...... :::.:: :..:::::
CCDS98 HCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTND-VCSEPLRGHRTTYTE
1550 1560 1570 1580 1590 1600
1180 1190 1200 1210 1220
pF1KB3 CCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSE--QYTPEADPY
::: ::::..:::::: ..:. ::::::. : :.: : : .: : :
CCDS98 CCCQDGEAWSQQCALCPPRSSEVYAQLCNVA----RIEAEREAGVHFRPGYEYGPGPDDL
1610 1620 1630 1640 1650 1660
1230 1240 1250 1260 1270 1280
pF1KB3 FIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECD
CCDS98 HYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVASHPE
1670 1680 1690 1700 1710 1720
>>CCDS32232.1 FBN1 gene_id:2200|Hs108|chr15 (2871 aa)
initn: 1029 init1: 586 opt: 1172 Z-score: 790.3 bits: 159.7 E(32554): 1.1e-37
Smith-Waterman score: 2254; 35.2% identity (59.1% similar) in 1003 aa overlap (213-1197:833-1747)
190 200 210 220 230 240
pF1KB3 QKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQC
: .... . . .: : :.: .: ..:
CCDS32 KTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRC
810 820 830 840 850 860
250 260 270 280 290 300
pF1KB3 GKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDIN
. : . . .::...:..:: . : : : : ::.:...: :.::.
CCDS32 EININGATLKSQCCSSLGAAWG-SPCTLCQVDPI---------CGKGYSRIKGTQCEDID
870 880 890 900 910
310 320 330 340 350 360
pF1KB3 ECQL-QGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGR
::.. ::: :: :.:: ::..: : :. : : :. : : :. : .
CCDS32 ECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD----IRLET--CF-LRYEDE
920 930 940 950 960
370 380 390 400 410 420
pF1KB3 QCMHPLSVHLTKQLCCCSVGKAWGPH-CEKCPLPGTAKEEPVEALTFSREHGPGVAEPEV
.: :.. . . :::::: ::: . ::.::. .: . : . .::: : :.
CCDS32 ECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCP------RGPGFATKEI
970 980 990 1000 1010
430 440 450 460 470 480
pF1KB3 ATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEAST
... : . : .. :. : .. : . .: . . ...
CCDS32 TNGKPFFK----DINECKMIP----------SLCTHGKCRNTIGS------FKCRCDSGF
1020 1030 1040 1050
490 500 510 520 530
pF1KB3 SSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRK-CVDIDE
. :. . :.:.:: ..::.:: :.:.: : . : : :::. . .. : :.::::
CCDS32 ALDSE---ERNCTDIDECRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDE
1060 1070 1080 1090 1100 1110
540 550 560 570 580 590
pF1KB3 CTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVG
: . :: : :.:::::. : :: : . : . . :::..:: : .: .:.::: .:
CCDS32 CQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIG
1120 1130 1140 1150 1160 1170
600 610 620 630 640 650
pF1KB3 AFRCEYCDSGYRMT-QRGRCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ
..: :. ::. : .: : ::::: . . : . :.:: :::.: : :: :
CCDS32 KYQCA-CNPGYHSTPDRLFCVDIDECSIMNGGC-ETFCTNSEGSYEC-SCQPGFALMPDQ
1180 1190 1200 1210 1220 1230
660 670 680 690 700 710
pF1KB3 --CLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVN
: :.::: . ::.: .:.:.:. : : : :. :. . : : : :..::. . :.:..
CCDS32 RSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS
1240 1250 1260 1270 1280 1290
720 730 740 750 760 770
pF1KB3 GQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCA-HGQCRNTEGSFQCVCDQG
: :.::.::: : : .::. . .: : ::.::. : :. :. : :: :::.: :. :
CCDS32 GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPG
1300 1310 1320 1330 1340 1350
780 790 800 810 820
pF1KB3 YRASGLGDHCEDINECLEDKSVC-QRGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-E
. ..:. .: :..:: . .: :..:: :: ::: : : .:. :. :: :..:: :
CCDS32 WIGDGI--KCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYT-GDGFTCTDLDECSE
1360 1370 1380 1390 1400 1410
830 840 850 860 870 880
pF1KB3 HPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSF
. .::: .:.:::. :...: :..:: ::::..::::::: ..: : : : : :
CCDS32 NLNLCG-NGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNIC-VFGTCHNLPGLF
1420 1430 1440 1450 1460
890 900 910 920 930 940
pF1KB3 RCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQC
:: : :.. ..: .:.::::: : .: . : :. ::..: : . : .: :
CCDS32 RCECEIGYELDRSGGNCTDVNEC-LDPTTCISGNCVNTPGSYICDCPPDF-ELNPTRVGC
1470 1480 1490 1500 1510 1520
950 960 970 980 990 1000
pF1KB3 RSRTSTDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCEIF
. : . .:. .:. . : . :.: .. .:.: :::. : .:: ::.
CCDS32 VDTRSGNCYLDI-RPRGD--------NGDTACSNEIGVGVSKASCCCSLGKAWGTPCEM-
1530 1540 1550 1560 1570
1010 1020 1030 1040 1050 1060
pF1KB3 PCPVLGTAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECL-LFGQEICKNGFCLNTRP
::...:.:. .:: :.:: : . .: ::: : : .:..: :.::
CCDS32 -CPAVNTSEYKILCPGGEGFRPNPITVI------LEDIDECQELPG--LCQGGKCINTFG
1580 1590 1600 1610 1620
1070 1080 1090 1100 1110 1120
pF1KB3 GYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRC
...: : : : . : :..::. :. : : : :: :.:.:.: .. . . :
CCDS32 SFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNC
1630 1640 1650 1660 1670 1680
1130 1140 1150 1160 1170 1180
pF1KB3 IRPAESNEQIEETDVYQDLCWE-HLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCA
. :. ..::.. . .:. .:. :. ..: ::: : :.::. :
CCDS32 M------------DMRRSLCYRNYYADNQTCDGELLFNMTKKM-CCCSYNIGRAWNKPCE
1690 1700 1710 1720 1730
1190 1200 1210 1220 1230 1240
pF1KB3 LCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAE
::. ..:..: :
CCDS32 QCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECP
1740 1750 1760 1770 1780 1790
>--
initn: 919 init1: 457 opt: 1235 Z-score: 832.3 bits: 167.5 E(32554): 4.9e-40
Smith-Waterman score: 1388; 30.9% identity (53.0% similar) in 879 aa overlap (35-892:80-832)
10 20 30 40 50 60
pF1KB3 LMCLLFFFSLPPLLVSNHTGRIKVVFTPSICKVTCTKGSCQNS-CEKGNTTTLISENGHA
: : . :: .. : . : : : :.
CCDS32 HDALKGPNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPS--GQI
50 60 70 80 90 100
70 80 90 100 110 120
pF1KB3 ADTLTATNFRVVICHLPCMNGGQCSSRDKCQCPPNFTGKLCQIPVHGASVPKLYQHSQQP
: . . ... :.. :::::.::. :.: : .. : : :: .. .
CCDS32 APSCGSRSIQH--CNIRCMNGGSCSD-DHCLCQKGYIGTHCGQPVCESGC-------LNG
110 120 130 140 150
130 140 150 160 170 180
pF1KB3 GKALGTHVIHSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQ
:. .. . :. . . : . : .. : : :. : ....: .
CCDS32 GRCVAPNRCACTYGF---TGPQCERDYRTGPCFTVI--------SNQMCQ-GQLSGIVCT
160 170 180 190 200
190 200 210 220 230 240
pF1KB3 KTKE-AQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQC
:: : :.. : : . . . .. ::.. . : : :.. ..:
CCDS32 KTLCCATVGRAW----GHPCEMCPA-QPHPCRRGFIPNI-------RTGAC-QDV--DEC
210 220 230 240 250
250 260 270 280 290 300
pF1KB3 GKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDIN
.:.::: . .: .:::. : .: :: :. : :.. . :.::.
CCDS32 -QAIPGLCQGGNCINTVGS---F-EC-KC---PAGHKLNEVSQK-----------CEDID
260 270 280 290
310 320 330 340 350 360
pF1KB3 ECQ-LQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGR
::. . :.: .::: ::..:: : : :: .: . :. : : :: ...::
CCDS32 ECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRP------GYCYTALTNGR
300 310 320 330 340
370 380 390 400 410
pF1KB3 QCMHPLSVHLTKQLCCCSVGKAWGPHC----EKCPLPGTAKEEPVEALTFSREHGPGVAE
: . : .::. :::..:. :.: : ::. .: . . .. . :
CCDS32 -CSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPP
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB3 PEVATAPPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVE-VAP
: .. :: .: :: : :: ::.:: : ::: . :
CCDS32 PPLGPIPPVLPVP----------PGFP---PG-------PQIPV------PRPPVEYLYP
410 420 430
480 490 500 510 520 530
pF1KB3 EASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD
: . :..::. : . .: :.:: : : : : .:... . . .:.:
CCDS32 ----SREPPRVLPVNVTDY--CQLVRYLCQNGRCIPTPGSYRCECNKGFQL-DLRGECID
440 450 460 470 480 490
540 550 560 570 580 590
pF1KB3 IDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPD-VCGEGHCVN
.::: . . :. :.: :..::. : : ::.... :.: :.::::. .:..:.:.:
CCDS32 VDECEK--NPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCIN
500 510 520 530 540
600 610 620 630 640 650
pF1KB3 TVGAFRCEYCDSGYRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR-GW
: :.:.: :..:...:. :. :::.::: . : . .:.: ::..:. : ::. .
CCDS32 TDGSFHC-VCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCI-CKPGFQLAS
550 560 570 580 590 600
660 670 680 690 700
pF1KB3 NGQ-CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDI---DECQQGNL
.:. : :..:: :..: :: : : .::: : : : . : . : : . : :
CCDS32 DGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGY-
610 620 630 640 650 660
710 720 730 740 750 760
pF1KB3 CVNGQC-KNTEGSF---RCTCGQG-YQLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQ
::: : :. .: :.. : .. . : . ... ::. : .. ::
CCDS32 -KRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS--
670 680 690 700 710 720
770 780 790 800 810 820
pF1KB3 CVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDN-KTCQD
::::: : ..: : : : :.: : : .:...:.. :.: :
CCDS32 -----------------DINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD
730 740 750 760
830 840 850 860 870 880
pF1KB3 INECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDN
:::: .: .:.: :: ::: :.: .:: . : .:::::::: ... : .: : :
CCDS32 INECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDEC-ESSPC-INGVCKN
770 780 790 800 810 820
890 900 910 920 930 940
pF1KB3 TAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSP
. ::: : :
CCDS32 SPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAW
830 840 850 860 870 880
>--
initn: 609 init1: 479 opt: 986 Z-score: 666.1 bits: 136.7 E(32554): 8.8e-31
Smith-Waterman score: 1831; 34.3% identity (57.3% similar) in 883 aa overlap (491-1330:1846-2650)
470 480 490 500 510 520
pF1KB3 VVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCI
: .. ::: :.::. :.::. . :.
CCDS32 PVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCL
1820 1830 1840 1850 1860 1870
530 540 550 560 570 580
pF1KB3 CYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVD
:. :.. ...: :.::.:: . :..: :.:: ::: : : ::. :... .:::::
CCDS32 CHTGFKTNDDQTMCLDINECER--DACGNGTCRNTIGSFNCRCNHGFILSHNN-DCIDVD
1880 1890 1900 1910 1920 1930
590 600 610 620 630
pF1KB3 ECLRPD--VCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECL-NPSTCPDEQCVN
:: . .: .:.:.::::.:.:. :. ::... :: : ::.::: .: : : :
CCDS32 ECASGNGNLCRNGQCINTVGSFQCQ-CNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQN
1940 1950 1960 1970 1980 1990
640 650 660 670 680 690
pF1KB3 SPGSYQCVPCTEGFRGWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDH
:::.:. : :. : .: :.:::.: :..:: : ::: :::. : : .:.. . .
CCDS32 LDGSYRCI-CPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSG
2000 2010 2020 2030 2040 2050
700 710 720
pF1KB3 KHCRDI--DECQ---QGNLCVNGQCKNT-----------EG--------------SFRCT
..:.:. . : .:. : . . .: :: .::
CCDS32 RRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQI
2060 2070 2080 2090 2100 2110
730 740 750 760 770 780
pF1KB3 CGQGYQLSAAKDQCE-DIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDIN
: : . .. :. :.:::.. .: :::: ::.::..: : :: . :..: : .
CCDS32 CPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILA--GNECVDTD
2120 2130 2140 2150 2160
790 800 810 820 830 840
pF1KB3 ECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTE
:: . : : : :. :...::: .::. ::.::::: ..: ::. . :.::
CCDS32 ECSVGNP-CGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR--CVNTY
2170 2180 2190 2200 2210 2220
850 860 870 880 890 900
pF1KB3 GSFHCVCQQGFSISADGRTCEDIDECVNNTV-C-DSHGFCDNTAGSFRCLCYQGFQAPQD
::..: : :. . : : :.: ::: .. : ... : : :.. :.: :.: :
CCDS32 GSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPD
2230 2240 2250 2260 2270 2280
910 920 930 940 950 960
pF1KB3 GQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVD
:.:::: :::. :.: .. : :..::. : : : . :: .: ::
CCDS32 GEGCVDENECQTKPGICENGRCLNTRGSYTCECND-GFTASPNQDEC-------LD----
2290 2300 2310 2320 2330
970 980 990 1000 1010
pF1KB3 QPKEEKKECYYNLNDASLCDNVLAPN---VTKQECCCTSGAGWGDNCEIFPCPVLGTAEF
... :. .. . ..:. . . : :::.:::: .: ::: .::: :: ::. :
CCDS32 ---NREGYCFTEVLQ-NMCQ-IGSSNRNPVTKSECCCDGGRGWGPHCEI--CPFQGTVAF
2340 2350 2360 2370 2380
1020 1030 1040 1050 1060 1070
pF1KB3 TEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTY
..::.:.::. : : ::: .. ...:.:: :.: : .:.: :: :
CCDS32 KKLCPHGRGFMTNGA-----------DIDECKVI-HDVCRNGECVNDRGSYHCICKTGYT
2390 2400 2410 2420 2430
1080 1090 1100 1110 1120 1130
pF1KB3 YDPVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQI
: . .: :..:: : :. : . : ::::::.: : . ..:. . . : ...
CCDS32 PDITGTSCVDLNECNQAPKPC-NFICKNTEGSYQCSCPKGYILQEDGRSC-------KDL
2440 2450 2460 2470 2480
1140 1150 1160 1170 1180 1190
pF1KB3 EETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQL
.: . : : ...: . : .: : : : . .. . : :.
CCDS32 DECATKQHNC------QFLCVNTIGG----FT-CKCPPG--FTQHHTSCI----DNNECT
2490 2500 2510 2520
1200 1210 1220 1230 1240 1250
pF1KB3 CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC
.: . : .. . ..: : . : :. .: :.. .:: . :..: :
CCDS32 SDINLCG-----SKGICQNTPGSFTCECQRGFSLDQTGSSCEDV--DECEGNHRCQHG-C
2530 2540 2550 2560 2570 2580
1260 1270 1280 1290 1300 1310
pF1KB3 VRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGY
. :: :.: .:: ::: ::: :. .. : .:.: :: :::::.: :.
CCDS32 QNIIGGYRCSCPQGYLQHYQWNQCVDENEC--LSAHI--CGGASCHNTLGSYKCMCPAGF
2590 2600 2610 2620 2630
1320 1330 1340
pF1KB3 VPSDKPNYCTPLNTALNLEKDSDLE
. . : .:
CCDS32 QYEQFSGGCQDINECGSAQAPCSYGCSNTEGGYLCGCPPGYFRIGQGHCVSGMGMGRGNP
2640 2650 2660 2670 2680 2690
>>CCDS34222.1 FBN2 gene_id:2201|Hs108|chr5 (2912 aa)
initn: 1160 init1: 626 opt: 1169 Z-score: 788.2 bits: 159.3 E(32554): 1.4e-37
Smith-Waterman score: 2207; 34.7% identity (59.2% similar) in 989 aa overlap (231-1198:896-1791)
210 220 230 240 250 260
pF1KB3 PVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVG
: :. . :.: . : . . .::.:.:
CCDS34 CRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLG
870 880 890 900 910 920
270 280 290 300 310
pF1KB3 TSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQL-QGVCPNGECLNTM
..:: . :..: . : : :.... :.:.:::.. ::::::.:.:.
CCDS34 AAWG-SPCERCELDTA---------CPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSK
930 940 950 960 970
320 330 340 350 360 370
pF1KB3 GSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCS
::..: : :. : : :. : :. :: : . .:.::. .. . :::.
CCDS34 GSFHCECPEGLTLDGTGRVCLD----IRMEQ--CY-LKWDEDECIHPVPGKFRMDACCCA
980 990 1000 1010 1020
380 390 400 410 420 430
pF1KB3 VGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAE-PEVATAPPEKEIPSLDQEKTK
:: ::: .::.:: ::: :: :.: .: : :. .: :. : . : .. :
CCDS34 VGAAWGTECEECPKPGT-KE--YETLC---PRGAGFANRGDVLTGRPFYK----DINECK
1030 1040 1050 1060 1070
440 450 460 470 480 490
pF1KB3 LEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINEC
::. . .:: .: .:. . . . :.:.::
CCDS34 AFPGMCTYGKCRNTIG---SFKC----------------RCNSGFALDMEERNCTDIDEC
1080 1090 1100 1110
500 510 520 530 540 550
pF1KB3 TVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRK-CVDIDECTQVQHLCSQGRCENTEG
..::.::.: :.: : . : :.:::. . .. : :.::::: . :: : : ::::
CCDS34 RISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEG
1120 1130 1140 1150 1160 1170
560 570 580 590 600 610
pF1KB3 SFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMT-QRG
:: : :: : : .:.:..:: : ..: .:.::: .:...: :. ::. : .:
CCDS34 SFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCS-CNPGYQATPDRQ
1180 1190 1200 1210 1220 1230
620 630 640 650 660 670
pF1KB3 RCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGW-NGQ-CLDVDECLE-PNVCANG
: :::::. . : ::.:: :::.: :.::. .:. : :.::: . :..: .:
CCDS34 GCTDIDECMIMNGGCDTQCTNSEGSYEC-SCSEGYALMPDGRSCADIDECENNPDICDGG
1240 1250 1260 1270 1280 1290
680 690 700 710 720 730
pF1KB3 DCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ-QGNLCVNGQCKNTEGSFRCTCGQGYQ
.:.:. : : : :. :. . : : : :..::. ..:.:. :.:.::.::: : : ::.
CCDS34 QCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYS
1300 1310 1320 1330 1340 1350
740 750 760 770 780
pF1KB3 LSAAKDQCEDIDECQ-HRHLC-AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECLED
.. . : :.:::. : : :..: : :::.: : .:. ..:. .: :..:: .
CCDS34 VKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGI--KCIDLDECSNG
1360 1370 1380 1390 1400 1410
790 800 810 820 830 840
pF1KB3 KSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGSFH
:. ..:.:: ::: :.: .:: :. ::.:..:: :. .:: .:.:::. :...
CCDS34 THQCSINAQCVNTPGSYRCACSEGFT-GDGFTCSDVDECAENINLC-ENGQCLNVPGAYR
1420 1430 1440 1450 1460 1470
850 860 870 880 890 900
pF1KB3 CVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD
: :..::. ..:.:.:.::::: ...: : :.: : :.:.: .:.. . : .:.:
CCDS34 CECEMGFTPASDSRSCQDIDECSFQNIC-VFGTCNNLPGMFHCICDDGYELDRTGGNCTD
1480 1490 1500 1510 1520 1530
910 920 930 940 950 960
pF1KB3 VNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEK
..:: . : ...: :. : . : : . : .: : .: : .
CCDS34 IDECADPIN-CVNGLCVNTPGRYECNCPPDFQ-LNPTGVGC-------VDNRVGN-----
1540 1550 1560 1570
970 980 990 1000 1010 1020
pF1KB3 KECYYNLN---DASL-CDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMCP
:: ... :.:: :.. .. .:... :::. : .::. :: :: ....:. .::
CCDS34 --CYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCE--TCPPVNSTEYYTLCP
1580 1590 1600 1610 1620 1630
1030 1040 1050 1060 1070 1080
pF1KB3 KGKGFVPAGESSSEAGGENYKDADECL-LFGQEICKNGFCLNTRPGYECYCKQGTYYDPV
:.:: : . .: ::: : : .:..: :.:: ...: : :: : .
CCDS34 GGEGFRPNPITII------LEDIDECQELPG--LCQGGNCINTFGSFQCECPQGYYLSED
1640 1650 1660 1670 1680
1090 1100 1110 1120 1130 1140
pF1KB3 KLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEETD
: :.::: :. : : : :: :.:.:.: .. . . :. :
CCDS34 TRICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCM------------D
1690 1700 1710 1720 1730
1150 1160 1170 1180 1190
pF1KB3 VYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKDSDDYAQLCN
. ...:.. . .: : ..: ::: : :.::. : :: . :. .:
CCDS34 MRKSFCYRSYNGT-TCENEL-PFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICG
1740 1750 1760 1770 1780 1790
1200 1210 1220 1230 1240 1250
pF1KB3 IPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVR
CCDS34 NIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDID
1800 1810 1820 1830 1840 1850
>--
initn: 946 init1: 391 opt: 1032 Z-score: 696.7 bits: 142.4 E(32554): 1.7e-32
Smith-Waterman score: 1381; 28.9% identity (50.6% similar) in 1028 aa overlap (163-1174:41-891)
140 150 160 170 180 190
pF1KB3 HSTHTLPLTVTSQQGVKVKFPPNIVNIHVKHPPEASVQIHQVSRIDGPTGQKTKEAQPG-
.:: .:. .. : . . .: .
CCDS34 LYFLWLGCVVLWAQGTAGQPQPPPPKPPRPQPPPQQVRSATAGSEGGFLAPEYREEGAAV
20 30 40 50 60 70
200 210 220 230 240 250
pF1KB3 QSQVSYQGLP-VQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLS
:.: .: : . .. .. :. : . . .: :. ..:: .. .
CCDS34 ASRVRRRGQQDVLRGPNVCGSRFHSYCCPGWKTLPGGNQ---CIVPICRNSCGDGFCSRP
80 90 100 110 120
260 270 280 290 300
pF1KB3 KQEDCC-GTVGTSWGFNKCQKCPKKPSYHGY--NQMMECLPGYKRVNNTFCQDINECQLQ
.. : : .... : .. :.: . : .. .: :: .:.: :
CCDS34 NMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYI---GTYCG-------Q
130 140 150 160 170
310 320 330 340 350 360
pF1KB3 GVCPNGECLN---TMGSYRCTCKIGF-GPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQC
:: :: : : .: ::.: :: ::. : : . :::. :.. ..:
CCDS34 PVCENG-CQNGGRCIGPNRCACVYGFTGPQ-----CERD-----YRTGPCFTQVNN-QMC
180 190 200 210 220
370 380 390 400 410 420
pF1KB3 MHPLS-VHLTKQLCCCSVGKAWGPHCEKCPLPGTAKEEPVEALTFSREHGPGVAEPEVAT
. :. . :: ::: ..:.::: :: :: :.:.
CCDS34 QGQLTGIVCTKTLCCATIGRAWGHPCEMCP-----------------------AQPQ---
230 240 250
430 440 450 460 470 480
pF1KB3 APPEKEIPSLDQEKTKLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSS
: . . :.: : .
CCDS34 ------------------PCRRGFIPNIRT-----------------------------G
260 270
490 500 510 520 530 540
pF1KB3 ASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQ
: : ...:: . : :: .:.::: . : : :.. :: .:: :::::.
CCDS34 ACQ--------DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECSI
280 290 300 310 320
550 560 570 580 590 600
pF1KB3 VQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRC
. .: :.: :: ::..:.:: :...: .:. ::: : .: : :: ::
CCDS34 IPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID----QRTGMCFSG-LVNG----RC
330 340 350 360 370
610 620 630 640 650 660
pF1KB3 EYCDSGYRMTQRGRCEDIDECLNPSTCPDEQC-VNSPGSYQCVPCTEGFRGWNGQCLDVD
: :::. : . .: . .: : : : : . :. . : .:. .: . .
CCDS34 AQELPG-RMTKMQCCCEPGRCWGIGTIP-EACPVRGSEEYRRL-CMDGL-PMGG--IPGS
380 390 400 410 420
670 680 690 700 710 720
pF1KB3 ECLEPN-VCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEG
.:. . .:: . .:. . :. : :. :: .. :
CCDS34 AGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIP-------------GG---NGFSPGVGG
430 440 450 460 470
730 740 750 760 770
pF1KB3 SFRCTCGQGYQLSAAKDQCEDIDECQHR-HLCAHGQCRNTEGSFQCVCDQGYRASGLGDH
. . ::: ... . :: :.:. .:: .:.: : .:..: :..::. .. ::
CCDS34 AGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGD-
480 490 500 510 520 530
780 790 800 810 820 830
pF1KB3 CEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNK-TCQDINECEHPGLCGPQGE
: :..:: . : :::.:: ::: : : ::: .: .: ::.:: . :. .:.
CCDS34 CIDVDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGR
540 550 560 570 580 590
840 850 860 870 880 890
pF1KB3 CLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQA
:.::.:::.:.:. :: ...::..: : :::.....: .:.: : :::.:.: ::
CCDS34 CVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMC-LNGMCINEDGSFKCICKPGFVL
600 610 620 630 640
900 910 920 930 940 950
pF1KB3 PQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDV
.:. :.::.::. :.: .. : : :::: : : : . .. : :
CCDS34 APNGRYCTDVDECQT-PGICMNGHCINSEGSFRCDCP-------PGLA-----VGMDGRV
650 660 670 680 690
960 970 980 990 1000 1010
pF1KB3 DVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTS-GAGWGDNCEIFPCPVLGTAE
:: . .. :: ... . .: . :::.::::.. :.:. :. :::. ..::
CCDS34 CVDT--HMRSTCYGGIKKG-VCVRPFPGAVTKSECCCANPDYGFGEPCQ--PCPAKNSAE
700 710 720 730 740 750
1020 1030 1040 1050 1060 1070
pF1KB3 FTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGT
: .: .: :.. : .: .:: : .:: ::.: : : .:.: :..:
CCDS34 FHGLCSSGVGITVDG-----------RDINECAL-DPDICANGICENLRGSYRCNCNSGY
760 770 780 790
1080 1090 1100 1110 1120 1130
pF1KB3 YYDPVKLQCFDMDECQ-DPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQ
: .:.:.::: . : .: : :: :::.: : .:. . . : :. ..
CCDS34 EPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETC----EDINE
800 810 820 830 840 850
1140 1150 1160 1170 1180 1190
pF1KB3 IEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQ
: . . : ..:.. : :.. . : :.
CCDS34 CESNPCVNGACRNNLGSFNCECSP--GSKLSSTGLICIDSLKGTCWLNIQDSRCEVNING
860 870 880 890 900 910
1200 1210 1220 1230 1240 1250
pF1KB3 LCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGR
CCDS34 ATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVN
920 930 940 950 960 970
>--
initn: 815 init1: 479 opt: 992 Z-score: 670.1 bits: 137.5 E(32554): 5.3e-31
Smith-Waterman score: 1791; 33.5% identity (57.0% similar) in 881 aa overlap (496-1330:1894-2697)
470 480 490 500 510 520
pF1KB3 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
::: :..:. : :..: : :::..:.
CCDS34 NADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGF
1870 1880 1890 1900 1910 1920
530 540 550 560 570 580
pF1KB3 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC--L
. :..: :.:.::: .: :..: :.:: ::. :.: :: .... .:.:.::: .
CCDS34 KASQDQTMCMDVDECE--RHPCGNGTCKNTVGSYNCLCYPGFELTHNN-DCLDIDECSSF
1930 1940 1950 1960 1970 1980
590 600 610 620 630 640
pF1KB3 RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECLN-PSTCPDEQCVNSPGSY
.:: .:.: : .:.:.: :. ::..: :. : : .::. :..: : : ::.
CCDS34 FGQVCRNGRCFNEIGSFKC-LCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSF
1990 2000 2010 2020 2030
650 660 670 680 690 700
pF1KB3 QCVPCTEGFRGWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD
.:. : :.. . .:.:..:: : ::.: :.:.: :...: : :.. . . ..: :
CCDS34 RCI-CPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD
2040 2050 2060 2070 2080 2090
710 720 730
pF1KB3 IDECQQGNLCVNGQCK-----NTEGSFRCTC----GQGY----QLS------AAKDQC--
. . ::.:. :: . .: : :.:. .: : .: :
CCDS34 TRQSFCFTNFENGKCSVPKAFNTTKA-KCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPY
2100 2110 2120 2130 2140 2150
740 750 760 770 780
pF1KB3 ------------EDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC
::..:: . .:..::: ::.:::.: : .:: . : .: : .::
CCDS34 GHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDEC
2160 2170 2180 2190 2200 2210
790 800 810 820 830 840
pF1KB3 LEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGS
. : : : :. ::..:.: .::. .:.::::: ..: ::. . :.:: ::
CCDS34 -SIGNPCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFR--CMNTFGS
2220 2230 2240 2250 2260 2270
850 860 870 880 890 900
pF1KB3 FHCVCQQGFSISADGRTCEDIDECVNNTV-CDSHGF-CDNTAGSFRCLCYQGFQAPQDGQ
..:.: :... : . :.:.:::... :.:.:. : : :.: :.: :. ::.
CCDS34 YECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGE
2280 2290 2300 2310 2320 2330
910 920 930 940 950 960
pF1KB3 GCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQP
:::: :::. :.: .. : :. ::. : : . : : : .: ::
CCDS34 GCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGT-EC-------LD------
2340 2350 2360 2370 2380
970 980 990 1000 1010 1020
pF1KB3 KEEKKECYYNLNDASLCDNVLAPN--VTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM
... :. .. . ..:. . . :::.:::: .: ::: .::. ::. :::.. ..
CCDS34 -NRQGLCFAEVLQ-TICQMASSSRNLVTKSECCCDGGRGWGHQCEL--CPLPGTAQYKKI
2390 2400 2410 2420 2430
1030 1040 1050 1060 1070 1080
pF1KB3 CPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYDP
::.: :.. : .: ::: .. ..: :: :.:: ...:.:: : :
CCDS34 CPHGPGYTTDG-----------RDIDECKVM-PNLCTNGQCINTMGSFRCFCKVGYTTDI
2440 2450 2460 2470 2480
1090 1100 1110 1120 1130 1140
pF1KB3 VKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEET
.:.:.::: :.:. : . : ::::::.: : . .::. . : : . .: .
CCDS34 SGTSCIDLDECSQSPKPC-NYICKNTEGSYQCSCPRGYVLQEDGKTC---KDLDECQTKQ
2490 2500 2510 2520 2530 2540
1150 1160 1170 1180 1190
pF1KB3 DVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLC-N
: :: . :. ..:. : : . :. .. : : .:: : .: :
CCDS34 HNCQFLCVNTLGG-FTCKCP---PGFTQHHTACIDNNECGSQPSLCGAKG------ICQN
2550 2560 2570 2580 2590
1200 1210 1220 1230 1240 1250
pF1KB3 IPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRCVR
: . .. : . : : . :.. .:: . :..: :
CCDS34 TPGS-----------------FSCECQRGFSLDATGLNCEDV--DECDGNHRCQHG-CQN
2600 2610 2620 2630
1260 1270 1280 1290 1300 1310
pF1KB3 VQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVP
. :: : : .:: ::: :::.. : : .:.: :: ::::: : :.
CCDS34 ILGGYRCGCPQGYIQHYQWNQCVDENECSNPNA----CGSASCYNTLGSYKCACPSGFSF
2640 2650 2660 2670 2680
1320 1330 1340
pF1KB3 SDKPNYCTPLNTALNLEKDSDLE
.. . : .:
CCDS34 DQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVGQGHCVSGMGFNKGQYLS
2690 2700 2710 2720 2730 2740
>>CCDS12196.1 FBN3 gene_id:84467|Hs108|chr19 (2809 aa)
initn: 1162 init1: 609 opt: 1138 Z-score: 767.7 bits: 155.5 E(32554): 1.9e-36
Smith-Waterman score: 2200; 34.7% identity (58.9% similar) in 991 aa overlap (231-1198:810-1703)
210 220 230 240 250 260
pF1KB3 PVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGLSKQEDCCGTVG
: :. . :.: : : : . .::.:.:
CCDS12 CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLG
780 790 800 810 820 830
270 280 290 300 310
pF1KB3 TSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNNTFCQDINECQ-LQGVCPNGECLNTM
..:: . :..: :. : :. :.... :.:.:::. . ::::::.:.::
CCDS12 AAWG-SPCERCEIDPA---------CARGFARMTGVTCDDVNECESFPGVCPNGRCVNTA
840 850 860 870 880
320 330 340 350 360 370
pF1KB3 GSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCS
::.:: : :. : . :: . : ::. : . .: : . ..::::
CCDS12 GSFRCECPEGLMLDASGRLCVD----VRLE--PCF-LRWDEDECGVTLPGKYRMDVCCCS
890 900 910 920 930 940
380 390 400 410 420 430
pF1KB3 VGKAWGPHCEKCPLPGTAKEEPVEALTFSR--EHGPGVAEPEVATAPPEKEIPSLDQEKT
.: .:: .:: :: : :.: :. .: : : . .. : . : ..
CCDS12 IGAVWGVECEACPDP--------ESLEFASLCPRGLGFASRDFLSGRPFYK----DVNEC
950 960 970 980 990
440 450 460 470 480 490
pF1KB3 KLEPGQPQLSPGISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINE
:. :: . .:. .: . : .. . .: . :.:.:
CCDS12 KVFPGLCTHGTCRNTV---GSF-------------HCACAGGFALDAQ---ERNCTDIDE
1000 1010 1020 1030
500 510 520 530 540 550
pF1KB3 CTVNPDICGAGHCINLPVRYTCICYEGYRFSEQ-QRKCVDIDECTQVQHLCSQGRCENTE
: ..::.:: : :.: : . : :. ::. . . ...:.:.:::.. :: : : ::.
CCDS12 CRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTD
1040 1050 1060 1070 1080 1090
560 570 580 590 600 610
pF1KB3 GSFLCICPAGFMASEEGTNCIDVDEC-LRPDVCGEGHCVNTVGAFRCEYCDSGYRMT-QR
::. : :: : . .:: : :.::: : .: .:.:::..:::.: : .:.. : .:
CCDS12 GSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCS-CHAGFQSTPDR
1100 1110 1120 1130 1140 1150
620 630 640 650 660 670
pF1KB3 GRCEDIDEC-LNPSTCPDEQCVNSPGSYQCVPCTEGFRGW-NGQ-CLDVDECLE-PNVCA
: ::.:: .. . : : .:.:. :::.: : .:. .:. : ::::: : : ::
CCDS12 QGCVDINECRVQNGGC-DVHCINTEGSYRC-SCGQGYSLMPDGRACADVDECEENPRVCD
1160 1170 1180 1190 1200
680 690 700 710 720
pF1KB3 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQG-NLCVNGQCKNTEGSFRCTCGQG
.: :.:. :.. : :. :. ::: . : :.:::. . ..:..:.:.::.::: : : :
CCDS12 QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLG
1210 1220 1230 1240 1250 1260
730 740 750 760 770 780
pF1KB3 YQLSAAKDQCEDIDECQ-HRHLC-AHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINECL
:.. . : :.:::. : : .:..: : :::.: : :. ..:. .:.:..::.
CCDS12 YMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGF--ECHDLDECV
1270 1280 1290 1300 1310 1320
790 800 810 820 830 840
pF1KB3 EDKSVCQ-RGDCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGECLNTEGS
.. :. ::::.:. ::: ::: .:: :. :.: .:: :. :: .:.:::. :.
CCDS12 SQEHRCSPRGDCLNVPGSYRCTCRQGFA-GDGFFCEDRDECAENVDLCD-NGQCLNAPGG
1330 1340 1350 1360 1370 1380
850 860 870 880 890 900
pF1KB3 FHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGC
..: :..::. . : :.:.:.:::.....: . : :.: : :::.: :.. . : .:
CCDS12 YRCECEMGFDPTEDHRACQDVDECAQGNLC-AFGSCENLPGMFRCICNGGYELDRGGGNC
1390 1400 1410 1420 1430 1440
910 920 930 940 950 960
pF1KB3 VDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKE
.:.::: . : .. : :. ::.:: : .. : .: : ::.
CCDS12 TDINECADPVN-CINGVCINTPGSYLCSCP-QDFELNPSGVGC---------VDT-----
1450 1460 1470 1480
970 980 990 1000 1010 1020
pF1KB3 EKKECYYNLNDAS----LCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEM
. .:. . .: . :. .. .::. :::. : .::. ::. ::. .:.:. .
CCDS12 RAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL--CPMANTTEYRTL
1490 1500 1510 1520 1530 1540
1030 1040 1050 1060 1070 1080
pF1KB3 CPKGKGFVPAGESSSEAGGENYKDADECL-LFGQEICKNGFCLNTRPGYECYCKQGTYYD
:: :.:: : . .: ::: : : .:..: :.:: ...: : : . .
CCDS12 CPGGEGFQPNRITVI------LEDIDECQELPG--LCQGGDCVNTFGSFQCECPPGYHLS
1550 1560 1570 1580 1590
1090 1100 1110 1120 1130
pF1KB3 PVKLQCFDMDECQDPSS-CIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE
: :.:::. :. : : : :: :.:.: : .. . . :.
CCDS12 EHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCM-----------
1600 1610 1620 1630 1640
1140 1150 1160 1170 1180 1190
pF1KB3 TDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLY--GEAWGMQCALCPLKDSDDYAQL
:. ...:..: . .:. :. . .: ::: : :.::. : :: : :: :
CCDS12 -DMRKSVCFRHYNG--TCQNELAFN-VTRKMCCCSYNIGQAWNRPCEACPTPISPDYQIL
1650 1660 1670 1680 1690 1700
1200 1210 1220 1230 1240 1250
pF1KB3 CNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSFEELQAEECGILNGCENGRC
:
CCDS12 CGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE
1710 1720 1730 1740 1750 1760
>--
initn: 1459 init1: 408 opt: 1295 Z-score: 872.5 bits: 174.9 E(32554): 2.8e-42
Smith-Waterman score: 1295; 33.5% identity (56.0% similar) in 668 aa overlap (231-865:185-806)
210 220 230 240 250
pF1KB3 PVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQETIGSQCGKALPGL-SKQEDCCGTV
: :: .. : . : :: . ::.::
CCDS12 CHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATV
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB3 GTSWGFNKCQKCPKKPSYHGYNQMMECLPGY-KRVNNTFCQDINECQ-LQGVCPNGECLN
: .::. :. :: .: : : :. ... :::..::: . :.: .: :.:
CCDS12 GRAWGL-PCELCPAQP--H------PCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVN
220 230 240 250 260
320 330 340 350 360 370
pF1KB3 TMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCC
.::..: : .: . . ..: : . : :. .. .:: : :. : :.. ::
CCDS12 MVGSFHCRCPVGHRLSDSSAAC-ED-----YRAGACFSVLFGGR-CAGDLAGHYTRRQCC
270 280 290 300 310
380 390 400 410 420 430
pF1KB3 CSVGKAW--GPHCEKCPLPGTAKEEPVEALTFSREHG-PGVAEPEVATAPPEKEIPSLDQ
:. :. : :: : :: :. . . . : . : ::. : . . : :
CCDS12 CDRGRCWAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLF-PGLLGFGSNGMGPPLGP
320 330 340 350 360 370
440 450 460 470 480
pF1KB3 EKTKLEP------GQPQLSPG---ISTIHLHPQFPVVIEKTSPPVPVEVAPEASTSSASQ
..:.: : :.:.:: :.: :. . . . :. . . : :.
CCDS12 --ARLNPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCEC
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB3 VIAPTQ-----VTEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDEC
.. :: ...::: .: : : :.:.: : : :: :.. . .. :::.:::
CCDS12 NVGYTQDVRGECIDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDEC
440 450 460 470 480 490
550 560 570 580 590 600
pF1KB3 TQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAF
:: ::: :::::: :.: ::: : .: ::.: .:: .: .: :.: :.:
CCDS12 IVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSF
500 510 520 530 540 550
610 620 630 640 650
pF1KB3 RCEYCDSGYRMTQRGR-CEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFR-GWNGQ-C
: : :. .. :. : ::::: .:. : . .:.:. ::..: : :. : .:. :
CCDS12 SC-LCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRC-QCLGGLAVGTDGRVC
560 570 580 590 600 610
660 670 680 690 700 710
pF1KB3 LDV---DEC---LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCV
.:. . : .: . :: ... : : : .::: . :: ::
CCDS12 VDTHVRSTCYGAIEKGSCARPFPGTVTKSE-CCC-----ANPDHGFG---EPCQ---LC-
620 630 640 650
720 730 740 750 760 770
pF1KB3 NGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQ-HRHLCAHGQCRNTEGSFQCVCDQG
:.. . :. :..: :. . : .::.:: ..::.: :.: .::..:::. :
CCDS12 --PAKDS-AEFQALCSSG--LGITTDG-RDINECALDPEVCANGVCENLRGSYRCVCNLG
660 670 680 690 700 710
780 790 800 810 820
pF1KB3 YRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQL-DDNKTCQDINECEH
:.:.. : : :..:: .. .:. : : :. :::.:.:: ::.. .:.. :.:..::
CCDS12 YEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDEC--
720 730 740 750 760 770
830 840 850 860 870 880
pF1KB3 PGLCGP--QGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGS
: .: .: : : ::. : : : .. .: : :
CCDS12 --LSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGA
780 790 800 810 820
890 900 910 920 930 940
pF1KB3 FRCLCYQGFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQ
CCDS12 SLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNT
830 840 850 860 870 880
>--
initn: 392 init1: 392 opt: 1289 Z-score: 868.5 bits: 174.1 E(32554): 4.7e-42
Smith-Waterman score: 1579; 34.3% identity (59.5% similar) in 711 aa overlap (496-1160:1807-2473)
470 480 490 500 510 520
pF1KB3 TSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTCICYEGY
::: :..:. : :.. : :.:..:.
CCDS12 NADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGF
1780 1790 1800 1810 1820 1830
530 540 550 560 570 580
pF1KB3 RFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDEC--L
. : .: :.::::: .. :..: :.: ::. :.: ::.....: .:.: ::: :
CCDS12 QASADQTLCMDIDECD--RQPCGNGTCKNIIGSYNCLCFPGFVVTHNG-DCVDFDECTTL
1840 1850 1860 1870 1880 1890
590 600 610 620 630 640
pF1KB3 RPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGR-CEDIDECLN-PSTCPDEQCVNSPGSY
.:: :::.::.:.:.: :..:...: :. : : .:::. .:: : : ::.
CCDS12 VGQVCRFGHCLNTAGSFHC-LCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSF
1900 1910 1920 1930 1940 1950
650 660 670 680 690 700
pF1KB3 QCVPCTEGFRGWNGQCLDVDECLE-PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRD
.:. : ::. . .:.:.::: : ::.: : :.: ::..: : :.. . . ..: :
CCDS12 RCI-CPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFD
1960 1970 1980 1990 2000 2010
710 720 730
pF1KB3 IDECQQGNLCVNGQCK-----NTEGSFRCTC----GQGY---------QLSAA-KDQC--
. . :.:. :: . :: : :.:. . ::: .. :
CCDS12 TRQSFCFTRFEAGKCSVPKAFNTTKT-RCCCSKRPGEGWGDPCELCPQEGSAAFQELCPF
2020 2030 2040 2050 2060 2070
740 750 760 770 780
pF1KB3 ------------EDIDEC-QHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC
::..:: .. .:..: : ::.:::.: : :: . : .: : .::
CCDS12 GHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDEC
2080 2090 2100 2110 2120 2130
790 800 810 820 830 840
pF1KB3 LEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGS
. : .: : :. :...:.: :::. ::.::.:: .: ::. . : :::::
CCDS12 SVGHP-CGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFR--CHNTEGS
2140 2150 2160 2170 2180
850 860 870 880 890 900
pF1KB3 FHCVCQQGFSISADGRTCEDIDECVNNTV-CDSHGF-CDNTAGSFRCLCYQGFQA-PQDG
. :.: :... :: :.:.:::... : ..:. : : :.: :.: :.. : .:
CCDS12 YLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSG
2190 2200 2210 2220 2230 2240
910 920 930 940 950 960
pF1KB3 QGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQ
.::.: :::. .: .. : :. ::: : : ::. . :: .:. :. :
CCDS12 EGCTDDNECHAQPDLCVNGRCVNTAGSFRCDC-DEGFQPSPTLTECH---------DIRQ
2250 2260 2270 2280 2290
970 980 990 1000 1010 1020
pF1KB3 PKEEKKECYYNLNDASLCDNVLAPN--VTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTE
:. .. . ..: .. . . ::. :::: .: ::: ::. ::. ::. . .
CCDS12 -----GPCFAEVLQ-TMCRSLSSSSEAVTRAECCCGGGRGWGPRCEL--CPLPGTSAYRK
2300 2310 2320 2330 2340
1030 1040 1050 1060 1070 1080
pF1KB3 MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCKQGTYYD
.::.:.:.. : .:.::: .... .: .: :.:. ...:.:. : :
CCDS12 LCPHGSGYTAEG-----------RDVDECRMLAH-LCAHGECINSLGSFRCHCQAGYTPD
2350 2360 2370 2380 2390
1090 1100 1110 1120 1130
pF1KB3 PVKLQCFDMDEC-QDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAESNEQIEE
. :.::::: : :. : : ::.::. : : . ..:. . . : . .: .
CCDS12 ATATTCLDMDECSQVPKPCT-FLCKNTKGSFLCSCPRGYLLEEDGRTC---KDLDECTSR
2400 2410 2420 2430 2440 2450
1140 1150 1160 1170 1180 1190
pF1KB3 TDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCN
: :: . .. ..: :
CCDS12 QHNCQFLCVNTVG-AFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCE
2460 2470 2480 2490 2500 2510
1342 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:15:21 2016 done: Thu Nov 3 12:15:22 2016
Total Scan time: 5.360 Total Display time: 1.080
Function used was FASTA [36.3.4 Apr, 2011]