Result of FASTA (omim) for
pF1KB3013
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3013, 456 aa
1>>>pF1KB3013 456 - 456 aa - 456 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3901+/-0.000509; mu= 12.2434+/- 0.031
mean_var=96.6394+/-19.016, 0's: 0 Z-trim(108.4): 72 B-trim: 25 in 1/50
Lambda= 0.130466
statistics sampled from 16403 (16454) to 16403 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.538), E-opt: 0.2 (0.193), width: 16
Scan time: 7.150
The best scores are: opt bits E(85289)
NP_002807 (OMIM: 604450) 26S proteasome non-ATPase ( 456) 2902 557.4 2.8e-158
NP_777360 (OMIM: 604450) 26S proteasome non-ATPase ( 436) 2551 491.3 2.1e-138
NP_001303270 (OMIM: 604450) 26S proteasome non-ATP ( 397) 2533 487.9 2e-137
NP_001244935 (OMIM: 616008) COP9 signalosome compl ( 352) 162 41.6 0.004
>>NP_002807 (OMIM: 604450) 26S proteasome non-ATPase reg (456 aa)
initn: 2902 init1: 2902 opt: 2902 Z-score: 2962.6 bits: 557.4 E(85289): 2.8e-158
Smith-Waterman score: 2902; 100.0% identity (100.0% similar) in 456 aa overlap (1-456:1-456)
10 20 30 40 50 60
pF1KB3 MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEGRLQEVIETLLSLEKQTRTASDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEGRLQEVIETLLSLEKQTRTASDM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 KLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 ERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 KYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD
370 380 390 400 410 420
430 440 450
pF1KB3 PNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
::::::::::::::::::::::::::::::::::::
NP_002 PNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
430 440 450
>>NP_777360 (OMIM: 604450) 26S proteasome non-ATPase reg (436 aa)
initn: 2551 init1: 2551 opt: 2551 Z-score: 2605.8 bits: 491.3 E(85289): 2.1e-138
Smith-Waterman score: 2736; 95.6% identity (95.6% similar) in 456 aa overlap (1-456:1-436)
10 20 30 40 50 60
pF1KB3 MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEGRLQEVIETLLSLEKQTRTASDM
:::::::::::::::::::::::::::::::::::: ::::
NP_777 MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAK--------------------ASDM
10 20 30 40
70 80 90 100 110 120
pF1KB3 VSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 VSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPI
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 KLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 KLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKK
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 ERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 ERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 LSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 LSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 KYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 KYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB3 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD
350 360 370 380 390 400
430 440 450
pF1KB3 PNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
::::::::::::::::::::::::::::::::::::
NP_777 PNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
410 420 430
>>NP_001303270 (OMIM: 604450) 26S proteasome non-ATPase (397 aa)
initn: 2533 init1: 2533 opt: 2533 Z-score: 2588.1 bits: 487.9 E(85289): 2e-137
Smith-Waterman score: 2533; 100.0% identity (100.0% similar) in 397 aa overlap (60-456:1-397)
30 40 50 60 70 80
pF1KB3 ECAKLAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIML
::::::::::::::::::::::::::::::
NP_001 MVSTSRILVAVVKMCYEAKEWDLLNENIML
10 20 30
90 100 110 120 130 140
pF1KB3 LSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB3 ATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKI
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB3 NTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB3 VVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB3 KGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDES
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB3 EAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKE
340 350 360 370 380 390
450
pF1KB3 EMIHNLQ
:::::::
NP_001 EMIHNLQ
>>NP_001244935 (OMIM: 616008) COP9 signalosome complex s (352 aa)
initn: 129 init1: 82 opt: 162 Z-score: 177.1 bits: 41.6 E(85289): 0.004
Smith-Waterman score: 208; 24.4% identity (56.2% similar) in 315 aa overlap (82-390:52-336)
60 70 80 90 100 110
pF1KB3 KQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTY
..:::. :. .: ... . ::.
NP_001 LAGKYRQILEKAIQLSGAEQLEALKAFVEAMVNENVSLVISR---------QLLTDFCTH
30 40 50 60 70
120 130 140 150 160 170
pF1KB3 VEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQV
. .. : : ::. . : : . : . . ::.: :.. : ..::..: . .
NP_001 LPNLPDSTAKEIYHFTLEKIQPRVISFEEQVASIRQHLASIYEKEEDWRNAAQVLVGIPL
80 90 100 110 120 130
180 190 200 210 220
pF1KB3 ETYGSMEKKERVEFILEQM----RLCLAVKDYIRTQIISKKINTKFFQEENT-EKLKLKY
:: : .:. :.. :: . :: : : .... .. . ..:.:.: :.:...:
NP_001 ET-G--QKQYNVDYKLETYLKIARLYLEDDDPVQAEAYINRAS--LLQNESTNEQLQIHY
140 150 160 170 180
230 240 250 260 270 280
pF1KB3 YNLMIQLDQHEGSYLSICKHYRAI-YDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSD
. .. ... ... ..: . : : : :::. . ::: .. .::: ...:
NP_001 KVCYARVLDYRRKFIEAAQRYNELSYKT--IVHESERLE-ALKHALHCTILASAGQQRSR
190 200 210 220 230 240
290 300 310 320 330 340
pF1KB3 LVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTE
.. . :.. ... : : :.. ...: . : : .: . . . :: . ::.
NP_001 MLATLFKDERCQQLAAYGILEKMYLD-RIIRGNQLQEFAAMLMPH----QKATTADGSSI
250 260 270 280 290
350 360 370 380 390 400
pF1KB3 EGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAK
: :.:::. .: :. ::..... ::.. . . :
NP_001 --------LDRAVIEHNLLSASKLYNNITFEELGALLEIPAAKHEKPCQRGISRSNHFVS
300 310 320 330 340 350
410 420 430 440 450
pF1KB3 VDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
NP_001 K
456 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:05:05 2016 done: Thu Nov 3 12:05:06 2016
Total Scan time: 7.150 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]