Result of FASTA (omim) for
pF1KB3011
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3011, 721 aa
1>>>pF1KB3011 721 - 721 aa - 721 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.0945+/-0.000669; mu= -34.5577+/- 0.040
mean_var=1037.0943+/-233.529, 0's: 0 Z-trim(113.4): 490 B-trim: 0 in 0/56
Lambda= 0.039826
statistics sampled from 22328 (22792) to 22328 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.267), width: 16
Scan time: 12.160
The best scores are: opt bits E(85289)
XP_005254594 (OMIM: 602904) PREDICTED: mitogen-act ( 721) 4839 295.7 4.4e-79
NP_002739 (OMIM: 602904) mitogen-activated protein ( 721) 4839 295.7 4.4e-79
XP_005254595 (OMIM: 602904) PREDICTED: mitogen-act ( 721) 4839 295.7 4.4e-79
XP_011520084 (OMIM: 602904) PREDICTED: mitogen-act ( 721) 4839 295.7 4.4e-79
XP_005254596 (OMIM: 602904) PREDICTED: mitogen-act ( 721) 4839 295.7 4.4e-79
XP_011524377 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 1791 120.4 2e-26
XP_005258356 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 1791 120.4 2e-26
XP_016881328 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 1791 120.4 2e-26
XP_011524376 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 1791 120.4 2e-26
XP_011524378 (OMIM: 176949) PREDICTED: mitogen-act ( 587) 1791 120.4 2e-26
NP_002738 (OMIM: 176949) mitogen-activated protein ( 587) 1791 120.4 2e-26
NP_001278969 (OMIM: 176949) mitogen-activated prot ( 233) 1175 84.6 5.1e-16
XP_011524379 (OMIM: 176949) PREDICTED: mitogen-act ( 412) 928 70.7 1.4e-11
NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 842 65.7 4e-10
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 773 61.7 6e-09
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 773 61.7 6e-09
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 785 62.8 6.3e-09
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 785 62.8 6.3e-09
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 785 62.8 6.3e-09
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 756 60.7 1.2e-08
XP_006721621 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 768 61.8 1.2e-08
XP_006721620 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 768 61.8 1.2e-08
XP_006721622 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 768 61.8 1.2e-08
NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 743 60.0 2e-08
NP_001278968 (OMIM: 176949) mitogen-activated prot ( 376) 737 59.6 2.6e-08
NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357) 710 58.1 7.3e-08
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 704 57.7 9.4e-08
XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 699 57.5 1.2e-07
NP_057315 (OMIM: 609476) serine/threonine-protein ( 527) 665 55.7 5.7e-07
XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283) 634 53.6 1.3e-06
NP_620583 (OMIM: 600289) mitogen-activated protein ( 307) 631 53.4 1.5e-06
XP_016865793 (OMIM: 600289) PREDICTED: mitogen-act ( 258) 627 53.1 1.6e-06
NP_620582 (OMIM: 600289) mitogen-activated protein ( 297) 627 53.2 1.8e-06
XP_016865790 (OMIM: 600289) PREDICTED: mitogen-act ( 301) 627 53.2 1.8e-06
XP_016865788 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 627 53.2 1.9e-06
XP_016865789 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 620 52.8 2.5e-06
NP_002745 (OMIM: 602899) mitogen-activated protein ( 365) 619 52.8 2.8e-06
XP_011522259 (OMIM: 602521) PREDICTED: mitogen-act ( 677) 621 53.3 3.8e-06
NP_620601 (OMIM: 602521) mitogen-activated protein ( 677) 621 53.3 3.8e-06
XP_016865792 (OMIM: 600289) PREDICTED: mitogen-act ( 270) 606 51.9 3.9e-06
XP_016865791 (OMIM: 600289) PREDICTED: mitogen-act ( 273) 606 51.9 3.9e-06
XP_016863929 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 587 51.0 1e-05
XP_006714332 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 587 51.1 1.1e-05
XP_016863917 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 587 51.1 1.1e-05
XP_016863916 (OMIM: 602897) PREDICTED: mitogen-act ( 426) 587 51.1 1.1e-05
XP_005263188 (OMIM: 602897) PREDICTED: mitogen-act ( 464) 587 51.1 1.2e-05
NP_001304996 (OMIM: 602897) mitogen-activated prot ( 464) 587 51.1 1.2e-05
XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 573 50.2 1.8e-05
XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 573 50.2 1.8e-05
XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 573 50.2 1.8e-05
>>XP_005254594 (OMIM: 602904) PREDICTED: mitogen-activat (721 aa)
initn: 4839 init1: 4839 opt: 4839 Z-score: 1540.7 bits: 295.7 E(85289): 4.4e-79
Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 721 aa overlap (1-721:1-721)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
670 680 690 700 710 720
pF1KB3 N
:
XP_005 N
>>NP_002739 (OMIM: 602904) mitogen-activated protein kin (721 aa)
initn: 4839 init1: 4839 opt: 4839 Z-score: 1540.7 bits: 295.7 E(85289): 4.4e-79
Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 721 aa overlap (1-721:1-721)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
670 680 690 700 710 720
pF1KB3 N
:
NP_002 N
>>XP_005254595 (OMIM: 602904) PREDICTED: mitogen-activat (721 aa)
initn: 4839 init1: 4839 opt: 4839 Z-score: 1540.7 bits: 295.7 E(85289): 4.4e-79
Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 721 aa overlap (1-721:1-721)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
670 680 690 700 710 720
pF1KB3 N
:
XP_005 N
>>XP_011520084 (OMIM: 602904) PREDICTED: mitogen-activat (721 aa)
initn: 4839 init1: 4839 opt: 4839 Z-score: 1540.7 bits: 295.7 E(85289): 4.4e-79
Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 721 aa overlap (1-721:1-721)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
670 680 690 700 710 720
pF1KB3 N
:
XP_011 N
>>XP_005254596 (OMIM: 602904) PREDICTED: mitogen-activat (721 aa)
initn: 4839 init1: 4839 opt: 4839 Z-score: 1540.7 bits: 295.7 E(85289): 4.4e-79
Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 721 aa overlap (1-721:1-721)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWERYHDC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFDTNYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDLSNWK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQSKEKSDKKGKSKCERNGLVKAQIALEEASQQLAGKEREKNQGFDFDSFIAGTIQLSSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HEPTDVVDKLNDLNSSVSQLELKSLISKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEDCFFINQFCEVRKDEQVEKENTYTSYLDKFFSRKEDTEMLETEPVEDGKLGERGHEEG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLNNSGEFLFNKQLESIGIPQFHSPVGSPLKSIQATLTPSAMKSSPQIPHQTYSSILKHL
670 680 690 700 710 720
pF1KB3 N
:
XP_005 N
>>XP_011524377 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 1542 init1: 968 opt: 1791 Z-score: 595.3 bits: 120.4 E(85289): 2e-26
Smith-Waterman score: 1947; 53.9% identity (74.7% similar) in 608 aa overlap (1-574:1-586)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
:::: . . ...:.:::.:..:..::: : ::::.::::. ..::.:::.:.: .:.:
XP_011 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::.:.:::.:..: : : ... .:::::::::::: .::
XP_011 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQ---GELFKFSVAYIVQEYMETDLARLLE
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
:: : ::::.:::::::::::::::::::::::::::.::.::::::::::::::::.:
XP_011 QGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::.::::::::::::::::::::::::::::::::::.::::::. ::::::::::
XP_011 HYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::.:::..:::..::: :.: .. . : ..:: .::: .. ::.::::.::::.
XP_011 MQLILETIPVIREEDKDELLRVMPSFVSSTW-EVKRPLRKLLPEVNSEAIDFLEKILTFN
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWE----R
:::::::: .:.::::: :: : ::: :.:::.::::.:::.:: ..:.. ::. :
XP_011 PMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 YHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFD
: :. .: : .::: :::: : . :.::::::: .. :..::.
XP_011 YPVSLSSDLEWRPDRCQDASEVQRDPRAGS-APLAEDVQVDPRKDSHSSSERFLEQ----
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 TNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDL
.. : : .. .:. ...:.::. : ::::.:.::... .:: :::::.::
XP_011 SHSSMERAFE-ADY----------GRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDL
420 430 440 450 460
480 490 500 510 520
pF1KB3 SNWKE------------QSKEKSDKKGKSKCERNGLVKA-QIALEEASQQLAGKEREKNQ
:.::. .. . :. .. : ::. : . :.:: ::. .
XP_011 SHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSA
470 480 490 500 510 520
530 540 550 560
pF1KB3 G---------------FDFDSFIAGTIQLSSQHEPTDVVD-KLNDLNSSVSQLELKSLI-
. ::.: ::. ...: .. : :. : ::.:::.. . .:.
XP_011 SPPGRPAPVDGGASPQFDLDVFISRALKLCTK--PEDLPDNKLGDLNGACIPEHPGDLVQ
530 540 550 560 570
570 580 590 600 610 620
pF1KB3 SKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFCEVRKDEQVEKENTYT
... :.:.
XP_011 TEAFSKERW
580
>>XP_005258356 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 1542 init1: 968 opt: 1791 Z-score: 595.3 bits: 120.4 E(85289): 2e-26
Smith-Waterman score: 1947; 53.9% identity (74.7% similar) in 608 aa overlap (1-574:1-586)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
:::: . . ...:.:::.:..:..::: : ::::.::::. ..::.:::.:.: .:.:
XP_005 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::.:.:::.:..: : : ... .:::::::::::: .::
XP_005 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQ---GELFKFSVAYIVQEYMETDLARLLE
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
:: : ::::.:::::::::::::::::::::::::::.::.::::::::::::::::.:
XP_005 QGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::.::::::::::::::::::::::::::::::::::.::::::. ::::::::::
XP_005 HYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::.:::..:::..::: :.: .. . : ..:: .::: .. ::.::::.::::.
XP_005 MQLILETIPVIREEDKDELLRVMPSFVSSTW-EVKRPLRKLLPEVNSEAIDFLEKILTFN
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWE----R
:::::::: .:.::::: :: : ::: :.:::.::::.:::.:: ..:.. ::. :
XP_005 PMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 YHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFD
: :. .: : .::: :::: : . :.::::::: .. :..::.
XP_005 YPVSLSSDLEWRPDRCQDASEVQRDPRAGS-APLAEDVQVDPRKDSHSSSERFLEQ----
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 TNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDL
.. : : .. .:. ...:.::. : ::::.:.::... .:: :::::.::
XP_005 SHSSMERAFE-ADY----------GRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDL
420 430 440 450 460
480 490 500 510 520
pF1KB3 SNWKE------------QSKEKSDKKGKSKCERNGLVKA-QIALEEASQQLAGKEREKNQ
:.::. .. . :. .. : ::. : . :.:: ::. .
XP_005 SHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSA
470 480 490 500 510 520
530 540 550 560
pF1KB3 G---------------FDFDSFIAGTIQLSSQHEPTDVVD-KLNDLNSSVSQLELKSLI-
. ::.: ::. ...: .. : :. : ::.:::.. . .:.
XP_005 SPPGRPAPVDGGASPQFDLDVFISRALKLCTK--PEDLPDNKLGDLNGACIPEHPGDLVQ
530 540 550 560 570
570 580 590 600 610 620
pF1KB3 SKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFCEVRKDEQVEKENTYT
... :.:.
XP_005 TEAFSKERW
580
>>XP_016881328 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 1542 init1: 968 opt: 1791 Z-score: 595.3 bits: 120.4 E(85289): 2e-26
Smith-Waterman score: 1947; 53.9% identity (74.7% similar) in 608 aa overlap (1-574:1-586)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
:::: . . ...:.:::.:..:..::: : ::::.::::. ..::.:::.:.: .:.:
XP_016 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::.:.:::.:..: : : ... .:::::::::::: .::
XP_016 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQ---GELFKFSVAYIVQEYMETDLARLLE
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
:: : ::::.:::::::::::::::::::::::::::.::.::::::::::::::::.:
XP_016 QGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::.::::::::::::::::::::::::::::::::::.::::::. ::::::::::
XP_016 HYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::.:::..:::..::: :.: .. . : ..:: .::: .. ::.::::.::::.
XP_016 MQLILETIPVIREEDKDELLRVMPSFVSSTW-EVKRPLRKLLPEVNSEAIDFLEKILTFN
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWE----R
:::::::: .:.::::: :: : ::: :.:::.::::.:::.:: ..:.. ::. :
XP_016 PMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 YHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFD
: :. .: : .::: :::: : . :.::::::: .. :..::.
XP_016 YPVSLSSDLEWRPDRCQDASEVQRDPRAGS-APLAEDVQVDPRKDSHSSSERFLEQ----
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 TNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDL
.. : : .. .:. ...:.::. : ::::.:.::... .:: :::::.::
XP_016 SHSSMERAFE-ADY----------GRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDL
420 430 440 450 460
480 490 500 510 520
pF1KB3 SNWKE------------QSKEKSDKKGKSKCERNGLVKA-QIALEEASQQLAGKEREKNQ
:.::. .. . :. .. : ::. : . :.:: ::. .
XP_016 SHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSA
470 480 490 500 510 520
530 540 550 560
pF1KB3 G---------------FDFDSFIAGTIQLSSQHEPTDVVD-KLNDLNSSVSQLELKSLI-
. ::.: ::. ...: .. : :. : ::.:::.. . .:.
XP_016 SPPGRPAPVDGGASPQFDLDVFISRALKLCTK--PEDLPDNKLGDLNGACIPEHPGDLVQ
530 540 550 560 570
570 580 590 600 610 620
pF1KB3 SKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFCEVRKDEQVEKENTYT
... :.:.
XP_016 TEAFSKERW
580
>>XP_011524376 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 1542 init1: 968 opt: 1791 Z-score: 595.3 bits: 120.4 E(85289): 2e-26
Smith-Waterman score: 1947; 53.9% identity (74.7% similar) in 608 aa overlap (1-574:1-586)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
:::: . . ...:.:::.:..:..::: : ::::.::::. ..::.:::.:.: .:.:
XP_011 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::.:.:::.:..: : : ... .:::::::::::: .::
XP_011 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQ---GELFKFSVAYIVQEYMETDLARLLE
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
:: : ::::.:::::::::::::::::::::::::::.::.::::::::::::::::.:
XP_011 QGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::.::::::::::::::::::::::::::::::::::.::::::. ::::::::::
XP_011 HYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::.:::..:::..::: :.: .. . : ..:: .::: .. ::.::::.::::.
XP_011 MQLILETIPVIREEDKDELLRVMPSFVSSTW-EVKRPLRKLLPEVNSEAIDFLEKILTFN
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWE----R
:::::::: .:.::::: :: : ::: :.:::.::::.:::.:: ..:.. ::. :
XP_011 PMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 YHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFD
: :. .: : .::: :::: : . :.::::::: .. :..::.
XP_011 YPVSLSSDLEWRPDRCQDASEVQRDPRAGS-APLAEDVQVDPRKDSHSSSERFLEQ----
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 TNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDL
.. : : .. .:. ...:.::. : ::::.:.::... .:: :::::.::
XP_011 SHSSMERAFE-ADY----------GRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDL
420 430 440 450 460
480 490 500 510 520
pF1KB3 SNWKE------------QSKEKSDKKGKSKCERNGLVKA-QIALEEASQQLAGKEREKNQ
:.::. .. . :. .. : ::. : . :.:: ::. .
XP_011 SHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSA
470 480 490 500 510 520
530 540 550 560
pF1KB3 G---------------FDFDSFIAGTIQLSSQHEPTDVVD-KLNDLNSSVSQLELKSLI-
. ::.: ::. ...: .. : :. : ::.:::.. . .:.
XP_011 SPPGRPAPVDGGASPQFDLDVFISRALKLCTK--PEDLPDNKLGDLNGACIPEHPGDLVQ
530 540 550 560 570
570 580 590 600 610 620
pF1KB3 SKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFCEVRKDEQVEKENTYT
... :.:.
XP_011 TEAFSKERW
580
>>XP_011524378 (OMIM: 176949) PREDICTED: mitogen-activat (587 aa)
initn: 1542 init1: 968 opt: 1791 Z-score: 595.3 bits: 120.4 E(85289): 2e-26
Smith-Waterman score: 1947; 53.9% identity (74.7% similar) in 608 aa overlap (1-574:1-586)
10 20 30 40 50 60
pF1KB3 MAEKFESLMNIHGFDLGSRYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLTDPQSVK
:::: . . ...:.:::.:..:..::: : ::::.::::. ..::.:::.:.: .:.:
XP_011 MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALSDARSMK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 HALREIKIIRRLDHDNIVKVFEILGPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLE
::::::::::::::::::::.:.:::.:..: : : ... .:::::::::::: .::
XP_011 HALREIKIIRRLDHDNIVKVYEVLGPKGTDLQ---GELFKFSVAYIVQEYMETDLARLLE
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 QGPLLEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFINTEDLVLKIGDFGLARIMDP
:: : ::::.:::::::::::::::::::::::::::.::.::::::::::::::::.:
XP_011 QGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTEDLVLKIGDFGLARIVDQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 HYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIFAEMLTGKTLFAGAHELEQ
::::::.::::::::::::::::::::::::::::::::::.::::::. ::::::::::
XP_011 HYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEMLTGRMLFAGAHELEQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 MQLILESIPVVHEEDRQELLSVIPVYIRNDMTEPHKPLTQLLPGISREALDFLEQILTFS
::::::.:::..:::..::: :.: .. . : ..:: .::: .. ::.::::.::::.
XP_011 MQLILETIPVIREEDKDELLRVMPSFVSSTW-EVKRPLRKLLPEVNSEAIDFLEKILTFN
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 PMDRLTAEEALSHPYMSIYSFPMDEPISSHPFHIEDEVDDILLMDETHSHIYNWE----R
:::::::: .:.::::: :: : ::: :.:::.::::.:::.:: ..:.. ::. :
XP_011 PMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEIDDIVLMAANQSQLSNWDTCSSR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB3 YHDCQFSEHDWPVHNNFDIDEVQLDPRALSDVTDEEEVQVDPRKYLDGDREKYLEDPAFD
: :. .: : .::: :::: : . :.::::::: .. :..::.
XP_011 YPVSLSSDLEWRPDRCQDASEVQRDPRAGS-APLAEDVQVDPRKDSHSSSERFLEQ----
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 TNYSTEPCWQYSDHHENKYCDLECSHTCNYKTRSSSYLDNLVWRESEVNHYYEPKLIIDL
.. : : .. .:. ...:.::. : ::::.:.::... .:: :::::.::
XP_011 SHSSMERAFE-ADY----------GRSCDYKVGSPSYLDKLLWRDNKPHHYSEPKLILDL
420 430 440 450 460
480 490 500 510 520
pF1KB3 SNWKE------------QSKEKSDKKGKSKCERNGLVKA-QIALEEASQQLAGKEREKNQ
:.::. .. . :. .. : ::. : . :.:: ::. .
XP_011 SHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHASPPADDPERRLSA
470 480 490 500 510 520
530 540 550 560
pF1KB3 G---------------FDFDSFIAGTIQLSSQHEPTDVVD-KLNDLNSSVSQLELKSLI-
. ::.: ::. ...: .. : :. : ::.:::.. . .:.
XP_011 SPPGRPAPVDGGASPQFDLDVFISRALKLCTK--PEDLPDNKLGDLNGACIPEHPGDLVQ
530 540 550 560 570
570 580 590 600 610 620
pF1KB3 SKSVSQEKQEKGMANLAQLEALYQSSWDSQFVSGGEDCFFINQFCEVRKDEQVEKENTYT
... :.:.
XP_011 TEAFSKERW
580
721 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 20:29:49 2016 done: Thu Nov 3 20:29:51 2016
Total Scan time: 12.160 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]