FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB2507, 394 aa
  1>>>pF1KB2507 394 - 394 aa - 394 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9875+/-0.000467; mu= 18.3044+/- 0.029
 mean_var=59.0718+/-11.896, 0's: 0 Z-trim(108.0): 17  B-trim: 12 in 1/48
 Lambda= 0.166872
 statistics sampled from 16068 (16077) to 16068 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.537), E-opt: 0.2 (0.189), width:  16
 Scan time:  7.020

The best scores are:                                      opt bits E(85289)
NP_003349 (OMIM: 602874) ceramide glucosyltransfer ( 394) 2699 658.7 6.9e-189
XP_005252243 (OMIM: 602874) PREDICTED: ceramide gl ( 266) 1842 452.3 6.4e-127
XP_016870596 (OMIM: 602874) PREDICTED: ceramide gl ( 239) 1251 310.0   4e-84


>>NP_003349 (OMIM: 602874) ceramide glucosyltransferase   (394 aa)
 initn: 2699 init1: 2699 opt: 2699  Z-score: 3512.1  bits: 658.7 E(85289): 6.9e-189
Smith-Waterman score: 2699; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB2 MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB2 GVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB2 INPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 INPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB2 AATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB2 KAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVAS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB2 LIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMT
              310       320       330       340       350       360

              370       380       390    
pF1KB2 IYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV
       ::::::::::::::::::::::::::::::::::
NP_003 IYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV
              370       380       390    

>>XP_005252243 (OMIM: 602874) PREDICTED: ceramide glucos  (266 aa)
 initn: 1842 init1: 1842 opt: 1842  Z-score: 2399.6  bits: 452.3 E(85289): 6.4e-127
Smith-Waterman score: 1842; 100.0% identity (100.0% similar) in 266 aa overlap (129-394:1-266)

      100       110       120       130       140       150        
pF1KB2 KKLLGKYPNVDARLFIGGKKVGINPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMV
                                     ::::::::::::::::::::::::::::::
XP_005                               MPGYEVAKYDLIWICDSGIRVIPDTLTDMV
                                             10        20        30

      160       170       180       190       200       210        
pF1KB2 NQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKD
               40        50        60        70        80        90

      220       230       240       250       260       270        
pF1KB2 VLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTK
              100       110       120       130       140       150

      280       290       300       310       320       330        
pF1KB2 LRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQ
              160       170       180       190       200       210

      340       350       360       370       380       390    
pF1KB2 GGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV
              220       230       240       250       260      

>>XP_016870596 (OMIM: 602874) PREDICTED: ceramide glucos  (239 aa)
 initn: 1251 init1: 1251 opt: 1251  Z-score: 1631.3  bits: 310.0 E(85289): 4e-84
Smith-Waterman score: 1251; 99.5% identity (100.0% similar) in 187 aa overlap (1-187:1-187)

               10        20        30        40        50        60
pF1KB2 MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB2 GVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB2 INPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB2 AATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMA
       ::::::.                                                     
XP_016 AATLEQMESRSVAQAGVQWRDLGSLQAPPPGFTPFSCLSLLSSWDYRCPPPCLANFLYF 
              190       200       210       220       230          




394 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 20:28:39 2016 done: Thu Nov  3 20:28:40 2016
 Total Scan time:  7.020 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]