Result of FASTA (omim) for
pF1KB1123
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB1123, 2549 aa
1>>>pF1KB1123 2549 - 2549 aa - 2549 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4544+/-0.000536; mu= 20.0570+/- 0.034
mean_var=84.3310+/-17.010, 0's: 0 Z-trim(108.3): 127 B-trim: 408 in 1/53
Lambda= 0.139663
statistics sampled from 16272 (16404) to 16272 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.517), E-opt: 0.2 (0.192), width: 16
Scan time: 16.620
The best scores are: opt bits E(85289)
NP_004949 (OMIM: 601231,616638) serine/threonine-p (2549) 16818 3400.3 0
XP_005263495 (OMIM: 601231,616638) PREDICTED: seri (2549) 16818 3400.3 0
XP_016856389 (OMIM: 601231,616638) PREDICTED: seri (2322) 15375 3109.5 0
XP_016856390 (OMIM: 601231,616638) PREDICTED: seri (2133) 14098 2852.2 0
XP_011539468 (OMIM: 601231,616638) PREDICTED: seri (1590) 10385 2104.0 0
XP_016856391 (OMIM: 601231,616638) PREDICTED: seri (1424) 9208 1866.8 0
XP_016862132 (OMIM: 210600,601215,614564) PREDICTE (2580) 625 137.5 2.2e-30
XP_011511227 (OMIM: 210600,601215,614564) PREDICTE (2582) 625 137.5 2.2e-30
NP_001175 (OMIM: 210600,601215,614564) serine/thre (2644) 625 137.5 2.3e-30
XP_011511226 (OMIM: 210600,601215,614564) PREDICTE (2646) 625 137.5 2.3e-30
XP_006718908 (OMIM: 114480,208900,607585) PREDICTE (1708) 577 127.8 1.3e-27
XP_011541147 (OMIM: 114480,208900,607585) PREDICTE (2620) 577 127.9 1.8e-27
XP_011541146 (OMIM: 114480,208900,607585) PREDICTE (2708) 577 127.9 1.9e-27
XP_011541144 (OMIM: 114480,208900,607585) PREDICTE (3001) 577 127.9 2.1e-27
XP_011541142 (OMIM: 114480,208900,607585) PREDICTE (3056) 577 127.9 2.1e-27
XP_006718906 (OMIM: 114480,208900,607585) PREDICTE (3056) 577 127.9 2.1e-27
NP_000042 (OMIM: 114480,208900,607585) serine-prot (3056) 577 127.9 2.1e-27
XP_005271619 (OMIM: 114480,208900,607585) PREDICTE (3056) 577 127.9 2.1e-27
XP_016873278 (OMIM: 114480,208900,607585) PREDICTE (3056) 577 127.9 2.1e-27
XP_016873279 (OMIM: 114480,208900,607585) PREDICTE (3056) 577 127.9 2.1e-27
XP_005271618 (OMIM: 114480,208900,607585) PREDICTE (3056) 577 127.9 2.1e-27
XP_011541145 (OMIM: 114480,208900,607585) PREDICTE (2912) 370 86.2 7.3e-15
XP_016878556 (OMIM: 607032) PREDICTED: serine/thre (3059) 328 77.7 2.7e-12
XP_011544072 (OMIM: 607032) PREDICTED: serine/thre (3059) 328 77.7 2.7e-12
XP_005255241 (OMIM: 607032) PREDICTED: serine/thre (3637) 328 77.7 3.1e-12
NP_055907 (OMIM: 607032) serine/threonine-protein (3661) 328 77.7 3.2e-12
XP_016878555 (OMIM: 607032) PREDICTED: serine/thre (3663) 328 77.7 3.2e-12
XP_005255240 (OMIM: 607032) PREDICTED: serine/thre (3663) 328 77.7 3.2e-12
XP_011544071 (OMIM: 607032) PREDICTED: serine/thre (3688) 328 77.7 3.2e-12
XP_005255239 (OMIM: 607032) PREDICTED: serine/thre (3689) 328 77.7 3.2e-12
NP_008835 (OMIM: 600899,615966) DNA-dependent prot (4128) 305 73.1 8.7e-11
NP_001075109 (OMIM: 600899,615966) DNA-dependent p (4097) 271 66.3 1e-08
XP_011524333 (OMIM: 602609) PREDICTED: phosphatidy ( 701) 206 52.9 1.8e-05
NP_001294949 (OMIM: 602609) phosphatidylinositol 3 ( 824) 206 52.9 2.1e-05
NP_002638 (OMIM: 602609) phosphatidylinositol 3-ki ( 887) 206 53.0 2.2e-05
NP_001242974 (OMIM: 602925) phosphatidylinositol 4 ( 582) 191 49.9 0.00012
XP_016862110 (OMIM: 602925) PREDICTED: phosphatidy ( 657) 191 49.9 0.00014
XP_016862109 (OMIM: 602925) PREDICTED: phosphatidy ( 674) 191 49.9 0.00014
XP_016856974 (OMIM: 602839,615513) PREDICTED: phos (1015) 193 50.4 0.00015
XP_016856973 (OMIM: 602839,615513) PREDICTED: phos (1043) 193 50.4 0.00016
XP_006710752 (OMIM: 602839,615513) PREDICTED: phos (1044) 193 50.4 0.00016
XP_006710750 (OMIM: 602839,615513) PREDICTED: phos (1044) 193 50.4 0.00016
NP_005017 (OMIM: 602839,615513) phosphatidylinosit (1044) 193 50.4 0.00016
XP_016856972 (OMIM: 602839,615513) PREDICTED: phos (1074) 193 50.4 0.00016
XP_016856967 (OMIM: 602839,615513) PREDICTED: phos (1103) 193 50.4 0.00016
XP_016856970 (OMIM: 602839,615513) PREDICTED: phos (1103) 193 50.4 0.00016
XP_016856971 (OMIM: 602839,615513) PREDICTED: phos (1103) 193 50.4 0.00016
XP_016856965 (OMIM: 602839,615513) PREDICTED: phos (1103) 193 50.4 0.00016
XP_016856966 (OMIM: 602839,615513) PREDICTED: phos (1103) 193 50.4 0.00016
XP_016856969 (OMIM: 602839,615513) PREDICTED: phos (1103) 193 50.4 0.00016
>>NP_004949 (OMIM: 601231,616638) serine/threonine-prote (2549 aa)
initn: 16818 init1: 16818 opt: 16818 Z-score: 18299.8 bits: 3400.3 E(85289): 0
Smith-Waterman score: 16818; 100.0% identity (100.0% similar) in 2549 aa overlap (1-2549:1-2549)
10 20 30 40 50 60
pF1KB1 MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 KDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 LWTLGQLVASTGYVVELYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_004 LWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 VFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB1 RHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB1 STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB1 AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB1 VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB1 GELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB1 WTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLA
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB1 QQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWW
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB1 ERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVD
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB1 PSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB1 QELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEA
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB1 VLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSP
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB1 TPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVN
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB1 EALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVAS
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB1 KSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFG
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB1 ERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQA
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB1 WDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 WDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSL
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB1 QVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB1 SIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTL
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB1 MQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRH
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB1 PSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITC
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB1 HTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDG
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KB1 VELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLD
2470 2480 2490 2500 2510 2520
2530 2540
pF1KB1 VPTQVELLIKQATSHENLCQCYIGWCPFW
:::::::::::::::::::::::::::::
NP_004 VPTQVELLIKQATSHENLCQCYIGWCPFW
2530 2540
>>XP_005263495 (OMIM: 601231,616638) PREDICTED: serine/t (2549 aa)
initn: 16818 init1: 16818 opt: 16818 Z-score: 18299.8 bits: 3400.3 E(85289): 0
Smith-Waterman score: 16818; 100.0% identity (100.0% similar) in 2549 aa overlap (1-2549:1-2549)
10 20 30 40 50 60
pF1KB1 MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 KDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 LWTLGQLVASTGYVVELYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_005 LWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 VFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB1 RHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB1 STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB1 AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB1 VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB1 GELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB1 WTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLA
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB1 QQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWW
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB1 ERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLQGCQRIVEDWQKILMVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVD
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB1 PSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSRQLDHPLPTVHPQVTYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB1 QELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QELHKLMARCFLKLGEWQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEA
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB1 VLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLHYKHQNQARDEKKKLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSP
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB1 TPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVN
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB1 EALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EALVEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVAS
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB1 KSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFG
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB1 ERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQA
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB1 WDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSL
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB1 QVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB1 SIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTL
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB1 MQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRH
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB1 PSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITC
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB1 HTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDG
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KB1 VELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VELGEPAHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLD
2470 2480 2490 2500 2510 2520
2530 2540
pF1KB1 VPTQVELLIKQATSHENLCQCYIGWCPFW
:::::::::::::::::::::::::::::
XP_005 VPTQVELLIKQATSHENLCQCYIGWCPFW
2530 2540
>>XP_016856389 (OMIM: 601231,616638) PREDICTED: serine/t (2322 aa)
initn: 15375 init1: 15375 opt: 15375 Z-score: 16729.1 bits: 3109.5 E(85289): 0
Smith-Waterman score: 15375; 100.0% identity (100.0% similar) in 2322 aa overlap (228-2549:1-2322)
200 210 220 230 240 250
pF1KB1 VWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEEAEKGFDETLAKEKGMNR
::::::::::::::::::::::::::::::
XP_016 MQKPQWYRHTFEEAEKGFDETLAKEKGMNR
10 20 30
260 270 280 290 300 310
pF1KB1 DDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMGFGTKPRHITPFT
40 50 60 70 80 90
320 330 340 350 360 370
pF1KB1 SFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESRCCRDLMEEKFDQVCQWV
100 110 120 130 140 150
380 390 400 410 420 430
pF1KB1 LKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQAL
160 170 180 190 200 210
440 450 460 470 480 490
pF1KB1 GLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGI
220 230 240 250 260 270
500 510 520 530 540 550
pF1KB1 QQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGM
280 290 300 310 320 330
560 570 580 590 600 610
pF1KB1 PKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKE
340 350 360 370 380 390
620 630 640 650 660 670
pF1KB1 IRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLA
400 410 420 430 440 450
680 690 700 710 720 730
pF1KB1 SLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQI
460 470 480 490 500 510
740 750 760 770 780 790
pF1KB1 LTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINN
520 530 540 550 560 570
800 810 820 830 840 850
pF1KB1 VLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEP
580 590 600 610 620 630
860 870 880 890 900 910
pF1KB1 YRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSL
640 650 660 670 680 690
920 930 940 950 960 970
pF1KB1 SESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITF
700 710 720 730 740 750
980 990 1000 1010 1020 1030
pF1KB1 IFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTL
760 770 780 790 800 810
1040 1050 1060 1070 1080 1090
pF1KB1 MREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLL
820 830 840 850 860 870
1100 1110 1120 1130 1140 1150
pF1KB1 AAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIH
880 890 900 910 920 930
1160 1170 1180 1190 1200 1210
pF1KB1 PIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIV
940 950 960 970 980 990
1220 1230 1240 1250 1260 1270
pF1KB1 KGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSK
1000 1010 1020 1030 1040 1050
1280 1290 1300 1310 1320 1330
pF1KB1 DDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDEL
1060 1070 1080 1090 1100 1110
1340 1350 1360 1370 1380 1390
pF1KB1 IRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKAL
1120 1130 1140 1150 1160 1170
1400 1410 1420 1430 1440 1450
pF1KB1 HYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWE
1180 1190 1200 1210 1220 1230
1460 1470 1480 1490 1500 1510
pF1KB1 DALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAA
1240 1250 1260 1270 1280 1290
1520 1530 1540 1550 1560 1570
pF1KB1 AAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTA
1300 1310 1320 1330 1340 1350
1580 1590 1600 1610 1620 1630
pF1KB1 MAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKIL
1360 1370 1380 1390 1400 1410
1640 1650 1660 1670 1680 1690
pF1KB1 MVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVRSLVVSPHEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVT
1420 1430 1440 1450 1460 1470
1700 1710 1720 1730 1740 1750
pF1KB1 YAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEW
1480 1490 1500 1510 1520 1530
1760 1770 1780 1790 1800 1810
pF1KB1 QLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKL
1540 1550 1560 1570 1580 1590
1820 1830 1840 1850 1860 1870
pF1KB1 RHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTL
1600 1610 1620 1630 1640 1650
1880 1890 1900 1910 1920 1930
pF1KB1 LMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMYTVPAVQGFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQ
1660 1670 1680 1690 1700 1710
1940 1950 1960 1970 1980 1990
pF1KB1 VIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKN
1720 1730 1740 1750 1760 1770
2000 2010 2020 2030 2040 2050
pF1KB1 MCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAM
1780 1790 1800 1810 1820 1830
2060 2070 2080 2090 2100 2110
pF1KB1 MERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQ
1840 1850 1860 1870 1880 1890
2120 2130 2140 2150 2160 2170
pF1KB1 LTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSLELQYVSPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGS
1900 1910 1920 1930 1940 1950
2180 2190 2200 2210 2220 2230
pF1KB1 NGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLI
1960 1970 1980 1990 2000 2010
2240 2250 2260 2270 2280 2290
pF1KB1 GWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGD
2020 2030 2040 2050 2060 2070
2300 2310 2320 2330 2340 2350
pF1KB1 DLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHID
2080 2090 2100 2110 2120 2130
2360 2370 2380 2390 2400 2410
pF1KB1 FGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAV
2140 2150 2160 2170 2180 2190
2420 2430 2440 2450 2460 2470
pF1KB1 LEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE
2200 2210 2220 2230 2240 2250
2480 2490 2500 2510 2520 2530
pF1KB1 SIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHEN
2260 2270 2280 2290 2300 2310
2540
pF1KB1 LCQCYIGWCPFW
::::::::::::
XP_016 LCQCYIGWCPFW
2320
>>XP_016856390 (OMIM: 601231,616638) PREDICTED: serine/t (2133 aa)
initn: 14098 init1: 14098 opt: 14098 Z-score: 15339.1 bits: 2852.2 E(85289): 0
Smith-Waterman score: 14098; 100.0% identity (100.0% similar) in 2133 aa overlap (417-2549:1-2133)
390 400 410 420 430 440
pF1KB1 LIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHVLSCVKKEKERTAAFQALGLLSVAVRS
::::::::::::::::::::::::::::::
XP_016 MNHVLSCVKKEKERTAAFQALGLLSVAVRS
10 20 30
450 460 470 480 490 500
pF1KB1 EFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDATVFTCISMLARAMGPGIQQDIKELLE
40 50 60 70 80 90
510 520 530 540 550 560
pF1KB1 PMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLRHPGMPKGLAHQLA
100 110 120 130 140 150
570 580 590 600 610 620
pF1KB1 SPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPGLTTLPEASDVGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTC
160 170 180 190 200 210
630 640 650 660 670 680
pF1KB1 SRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERFDAH
220 230 240 250 260 270
690 700 710 720 730 740
pF1KB1 LAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGI
280 290 300 310 320 330
750 760 770 780 790 800
pF1KB1 GRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPNPGVINNVLATIGELA
340 350 360 370 380 390
810 820 830 840 850 860
pF1KB1 QVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVELYRKYPTLLE
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 QVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLE
400 410 420 430 440 450
870 880 890 900 910 920
pF1KB1 VLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLSESKSSQDS
460 470 480 490 500 510
930 940 950 960 970 980
pF1KB1 SDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFRDQSLSHHHTMVVQAITFIFKSLGLKC
520 530 540 550 560 570
990 1000 1010 1020 1030 1040
pF1KB1 VQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMNT
580 590 600 610 620 630
1050 1060 1070 1080 1090 1100
pF1KB1 SIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLRVFMHDNSPGRIVSIKLLAAIQLFGAN
640 650 660 670 680 690
1110 1120 1130 1140 1150 1160
pF1KB1 LDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQS
700 710 720 730 740 750
1170 1180 1190 1200 1210 1220
pF1KB1 PELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLICRIVKGYTLADEE
760 770 780 790 800 810
1230 1240 1250 1260 1270 1280
pF1KB1 EDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDPLIYQHRMLRSGQGDALASGPVETGPMKKLHVSTINLQKAWGAARRVSKDDWLEWLRR
820 830 840 850 860 870
1290 1300 1310 1320 1330 1340
pF1KB1 LSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELNEDQQDELIRSIELALT
880 890 900 910 920 930
1350 1360 1370 1380 1390 1400
pF1KB1 SQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKALHYKELEFQK
940 950 960 970 980 990
1410 1420 1430 1440 1450 1460
pF1KB1 GPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKK
1000 1010 1020 1030 1040 1050
1470 1480 1490 1500 1510 1520
pF1KB1 MDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEKWTLVNDETQAKMARMAAAAAWGLGQW
1060 1070 1080 1090 1100 1110
1530 1540 1550 1560 1570 1580
pF1KB1 DSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARDLLDAELTAMAGESYSRA
1120 1130 1140 1150 1160 1170
1590 1600 1610 1620 1630 1640
pF1KB1 YGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSP
1180 1190 1200 1210 1220 1230
1650 1660 1670 1680 1690 1700
pF1KB1 HEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEDMRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQVTYAYMKNMWK
1240 1250 1260 1270 1280 1290
1710 1720 1730 1740 1750 1760
pF1KB1 SARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGEWQLNLQGINE
1300 1310 1320 1330 1340 1350
1770 1780 1790 1800 1810 1820
pF1KB1 STIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHYKHQNQARDEKKKLRHASGANIT
1360 1370 1380 1390 1400 1410
1830 1840 1850 1860 1870 1880
pF1KB1 NATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSKTLLMYTVPAVQ
1420 1430 1440 1450 1460 1470
1890 1900 1910 1920 1930 1940
pF1KB1 GFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFFRSISLSRGNNLQDTLRVLTLWFDYGHWPDVNEALVEGVKAIQIDTWLQVIPQLIARI
1480 1490 1500 1510 1520 1530
1950 1960 1970 1980 1990 2000
pF1KB1 DTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANKILKNMCEHSNTLV
1540 1550 1560 1570 1580 1590
2010 2020 2030 2040 2050 2060
pF1KB1 QQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLK
1600 1610 1620 1630 1640 1650
2070 2080 2090 2100 2110 2120
pF1KB1 ETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYV
1660 1670 1680 1690 1700 1710
2130 2140 2150 2160 2170 2180
pF1KB1 SPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPKLLMCRDLELAVPGTYDPNQPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLL
1720 1730 1740 1750 1760 1770
2190 2200 2210 2220 2230 2240
pF1KB1 KGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTL
1780 1790 1800 1810 1820 1830
2250 2260 2270 2280 2290 2300
pF1KB1 HALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLK
1840 1850 1860 1870 1880 1890
2310 2320 2330 2340 2350 2360
pF1KB1 SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAM
1900 1910 1920 1930 1940 1950
2370 2380 2390 2400 2410 2420
pF1KB1 TREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPL
1960 1970 1980 1990 2000 2010
2430 2440 2450 2460 2470 2480
pF1KB1 LNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEPAHKKTGTTVPESIHSFIGDG
2020 2030 2040 2050 2060 2070
2490 2500 2510 2520 2530 2540
pF1KB1 LVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVELLIKQATSHENLCQCYIGWC
2080 2090 2100 2110 2120 2130
pF1KB1 PFW
:::
XP_016 PFW
>>XP_011539468 (OMIM: 601231,616638) PREDICTED: serine/t (1590 aa)
initn: 10385 init1: 10385 opt: 10385 Z-score: 11297.9 bits: 2104.0 E(85289): 0
Smith-Waterman score: 10385; 99.9% identity (99.9% similar) in 1588 aa overlap (1-1588:1-1588)
10 20 30 40 50 60
pF1KB1 MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 KDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 LWTLGQLVASTGYVVELYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_011 LWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 VFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB1 RHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB1 STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB1 AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB1 VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB1 GELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB1 WTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTLVNDETQAKMARMAAAAAWGLGQWDSMEEYTCMIPRDTHDGAFYRAVLALHQDLFSLA
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB1 QQCIDKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWW
::::::::::::::::::::::::::::
XP_011 QQCIDKARDLLDAELTAMAGESYSRAYGIP
1570 1580 1590
>>XP_016856391 (OMIM: 601231,616638) PREDICTED: serine/t (1424 aa)
initn: 9338 init1: 9208 opt: 9208 Z-score: 10017.0 bits: 1866.8 E(85289): 0
Smith-Waterman score: 9208; 99.7% identity (99.9% similar) in 1420 aa overlap (1-1420:1-1420)
10 20 30 40 50 60
pF1KB1 MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLGTGPAAATTAATTSSNVSVLQQFASGLKSRNEETRAKAAKELQHYVTMELREMSQEES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRFYDQLNHHIFELVSSSDANERKGGILAIASLIGVEGGNATRIGRFANYLRNLLPSNDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVMEMASKAIGRLAMAGDTFTAEYVEFEVKRALEWLGADRNEGRRHAAVLVLRELAISVP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFFFQQVQPFFDNIFVAVWDPKQAIREGAVAALRACLILTTQREPKEMQKPQWYRHTFEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEKGFDETLAKEKGMNRDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 KDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLMGFGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTSPSPAKSTLVESR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCRDLMEEKFDQVCQWVLKCRNSKNSLIQMTILNLLPRLAAFRPSAFTDTQYLQDTMNHV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPPKDFAHKRQKAMQVDA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVFTCISMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKDIQDGLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMLSLVLMHKPLRHPGMPKGLAHQLASPGLTTLPEASDVGSITLALRTLGSFEFEGHSLT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVSQTAVQVVADVLSKLL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLKDPDPDPNPGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLLAKRQVA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 LWTLGQLVASTGYVVELYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 LWTLGQLVASTGYVVEPYRKYPTLLEVLLNFLKTEQNQGTRREAIRVLGLLGALDPYKHK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNIGMIDQSRDASAVSLSESKSSQDSSDYSTSEMLVNMGNLPLDEFYPAVSMVALMRIFR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQSLSHHHTMVVQAITFIFKSLGLKCVQFLPQVMPTFLNVIRVCDGAIREFLFQQLGMLV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFVKSHIRPYMDEIVTLMREFWVMNTSIQSTIILLIEQIVVALGGEFKLYLPQLIPHMLR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 VFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFMHDNSPGRIVSIKLLAAIQLFGANLDDYLHLLLPPIVKLFDAPEAPLPSRKAALETVD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLTESLDFTDYASRIIHPIVRTLDQSPELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB1 RHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHRINHQRYDVLICRIVKGYTLADEEEDPLIYQHRMLRSGQGDALASGPVETGPMKKLHV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB1 STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STINLQKAWGAARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB1 AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFVSCWSELNEDQQDELIRSIELALTSQDIAEVTQTLLNLAEFMEHSDKGPLPLRDDNGI
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB1 VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHF
::::::::::::::::::::::::::::::::::::: ..
XP_016 VLLGERAAKCRAYAKALHYKELEFQKGPTPAILESLIRVSLCSG
1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KB1 GELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCEK
>>XP_016862132 (OMIM: 210600,601215,614564) PREDICTED: s (2580 aa)
initn: 928 init1: 235 opt: 625 Z-score: 666.4 bits: 137.5 E(85289): 2.2e-30
Smith-Waterman score: 749; 24.1% identity (51.2% similar) in 1192 aa overlap (1389-2548:1583-2579)
1360 1370 1380 1390 1400 1410
pF1KB1 NLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKA-LHYKE-LEFQKGPTPAILESL
. .::..: .:.. . .: : :
XP_016 MVSTVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFL
1560 1570 1580 1590 1600 1610
1420 1430 1440 1450 1460 1470
pF1KB1 ISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPEL
.. ...:...::: : :. : .:.: .:: . ::. .. . :.
XP_016 QKLYAAMHEPDGVAGV-SAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIH
1620 1630 1640 1650 1660 1670
1480 1490 1500 1510 1520 1530
pF1KB1 MLGRMRCLEALGEWGQLHQQCCEKWTLVN-DETQAKMARMAAAAAWGLGQWDSMEEYTCM
. : .. . .::. . . : . . .: .: .. . . ::: :.::: .:.:
XP_016 YHGVVKSMLGLGQLSTVITQV--NGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAA
1680 1690 1700 1710 1720
1540 1550 1560 1570 1580
pF1KB1 IPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARD---LLDAE----LTAMAGE--SYSRA
:: . : : :.: .. : : :. :: :.: . : ::.:.
XP_016 ------DGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRG
1730 1740 1750 1760 1770 1780
1590 1600 1610 1620 1630 1640
pF1KB1 YGAMVSCHMLSELEEVIQ--YKLVP-ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLV
: .: ::: :::. :. .. : . . : ::. : . . :: .: .
XP_016 YEYIVRLHMLCELEHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRAL
1790 1800 1810 1820 1830 1840
1650 1660 1670 1680 1690
pF1KB1 VS----P-HEDM--RTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQV
.: : ...: . ::. : . :.:. :...: :.. :: ..
XP_016 LSLNKRPDYNEMVGECWLQSARVARKAGHHQTAYNAL---LNAGESRL---------AEL
1850 1860 1870 1880 1890
1700 1710 1720 1730 1740 1750
pF1KB1 TYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGE
: .:. : :. : . ..:. .. . .. . . . .: .: .:.
XP_016 YVERAKWLWS---KGDVHQALI----VLQKGVELCFPENETPPEGKNMLIHGRAMLLVGR
1900 1910 1920 1930 1940
1760 1770 1780 1790 1800 1810
pF1KB1 WQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHY-KHQNQARDEKK
.. . ... ..: : . .: . : .: . .: : . .. :.:
XP_016 FMEETANFESNAIMKKYKDVTACLPE----------WEDGHFYLAKYYDKLMPMVTDNK-
1950 1960 1970 1980 1990
1820 1830 1840 1850 1860 1870
pF1KB1 KLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSK
..:. :: .
XP_016 -------------------------------------------------MEKQ--GDLIR
2000
1880 1890 1900 1910 1920 1930
pF1KB1 TLLMYTVPAVQGFFRSISLSRGNNL--QDTLRVLTLWFDYGHWPDVNEALVEGVKAIQID
.... : :: :. ::.. :. :.::::.::: .:: .
XP_016 YIVLH-------FGRS--LQYGNQFIYQSMPRMLTLWLDYG------------TKAYE--
2010 2020 2030
1940 1950 1960 1970 1980 1990
pF1KB1 TWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANK
: .. .: : :. :. .:.:. . . .: . :: ..
XP_016 -WEKA-----GRSD-------RV--QMRNDLGKINKVITEHTNYLAPYQFLTA----FSQ
2040 2050 2060 2070 2080
2000 2010 2020 2030 2040 2050
pF1KB1 ILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEP
... .: ::. : ..: . .: . :: . .:. . : :. :.:.
XP_016 LISRIC-HSHDEVFVVLMEIIAKVFLAYPQQAMWM--MTAVSKSSYPMR-VNRCKEILN-
2090 2100 2110 2120 2130
2060 2070 2080 2090 2100 2110
pF1KB1 LHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISK
.:. . ..:.. . . : . : : : . .:. . :. . : :. ..:
XP_016 -KAIHMK--KSLEKFVGDATRLTDKL--LELCNKPV-DGSSSTLS----MSTH-FKMLKK
2140 2150 2160 2170 2180
2120 2130 2140 2150 2160
pF1KB1 QLPQLTSLELQYVSPKLLMCRDLE--LAVPGTYDPNQPI----IRIQSIAPSLQVITSKQ
. . : :. . . .: : :.. ... ..:. : .. .....: :
XP_016 LVEEATFSEI-LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQ
2190 2200 2210 2220 2230 2240
2170 2180 2190 2200 2210 2220
pF1KB1 RPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAV
.:.:..: ::.:. .... : ..:::.: :.:.. .:.: : .: : :..: :. :::
XP_016 KPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAV
2250 2260 2270 2280 2290 2300
2230 2240 2250 2260 2270 2280
pF1KB1 IPLSTNSGLIGWVPHCDTLHALI-RDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEV
:::. . :.: :: . :. .. . :.:: . . : : : : :. .:..:
XP_016 IPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC--MLPKSAALS--EKLKV
2310 2320 2330 2340 2350
2290 2300 2310 2320 2330 2340
pF1KB1 FEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLML
:.. . . . . :. :.. :. : :: :::::::::::::::: :...
XP_016 FREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILF
2360 2370 2380 2390 2400 2410
2350 2360 2370 2380 2390 2400
pF1KB1 DRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEV
: :.:. .:.::. :. . : : :: .:::::. ..:.: : .: .: .:...:..
XP_016 DSLTGECVHVDFNCLFNKGETFE-VPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRL
2420 2430 2440 2450 2460 2470
2410 2420 2430 2440 2450 2460
pF1KB1 LREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEP
.:.... .:.::..:..:::..: . .::.... :
XP_016 MRDQREPLMSVLKTFLHDPLVEW---SKPVKGHSKA-----------------------P
2480 2490 2500 2510
2470 2480 2490 2500 2510 2520
pF1KB1 AHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVE
.. :: .: :. .. . : .. .: . ..:...:: .: . .:.
XP_016 LNE-TGEVVNEKAKTHVLD--------IEQRLQGVIKTRNRVTGLPLS------IEGHVH
2520 2530 2540 2550
2530 2540
pF1KB1 LLIKQATSHENLCQCYIGWCPFW
::..::... ::: :.:: :.
XP_016 YLIQEATDENLLCQMYLGWTPYM
2560 2570 2580
>>XP_011511227 (OMIM: 210600,601215,614564) PREDICTED: s (2582 aa)
initn: 928 init1: 235 opt: 625 Z-score: 666.4 bits: 137.5 E(85289): 2.2e-30
Smith-Waterman score: 749; 24.1% identity (51.2% similar) in 1192 aa overlap (1389-2548:1585-2581)
1360 1370 1380 1390 1400 1410
pF1KB1 NLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKA-LHYKE-LEFQKGPTPAILESL
. .::..: .:.. . .: : :
XP_011 MVSTVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFL
1560 1570 1580 1590 1600 1610
1420 1430 1440 1450 1460 1470
pF1KB1 ISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPEL
.. ...:...::: : :. : .:.: .:: . ::. .. . :.
XP_011 QKLYAAMHEPDGVAGV-SAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIH
1620 1630 1640 1650 1660 1670
1480 1490 1500 1510 1520 1530
pF1KB1 MLGRMRCLEALGEWGQLHQQCCEKWTLVN-DETQAKMARMAAAAAWGLGQWDSMEEYTCM
. : .. . .::. . . : . . .: .: .. . . ::: :.::: .:.:
XP_011 YHGVVKSMLGLGQLSTVITQV--NGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAA
1680 1690 1700 1710 1720 1730
1540 1550 1560 1570 1580
pF1KB1 IPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARD---LLDAE----LTAMAGE--SYSRA
:: . : : :.: .. : : :. :: :.: . : ::.:.
XP_011 ------DGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRG
1740 1750 1760 1770 1780
1590 1600 1610 1620 1630 1640
pF1KB1 YGAMVSCHMLSELEEVIQ--YKLVP-ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLV
: .: ::: :::. :. .. : . . : ::. : . . :: .: .
XP_011 YEYIVRLHMLCELEHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRAL
1790 1800 1810 1820 1830 1840
1650 1660 1670 1680 1690
pF1KB1 VS----P-HEDM--RTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQV
.: : ...: . ::. : . :.:. :...: :.. :: ..
XP_011 LSLNKRPDYNEMVGECWLQSARVARKAGHHQTAYNAL---LNAGESRL---------AEL
1850 1860 1870 1880 1890
1700 1710 1720 1730 1740 1750
pF1KB1 TYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGE
: .:. : :. : . ..:. .. . .. . . . .: .: .:.
XP_011 YVERAKWLWS---KGDVHQALI----VLQKGVELCFPENETPPEGKNMLIHGRAMLLVGR
1900 1910 1920 1930 1940
1760 1770 1780 1790 1800 1810
pF1KB1 WQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHY-KHQNQARDEKK
.. . ... ..: : . .: . : .: . .: : . .. :.:
XP_011 FMEETANFESNAIMKKYKDVTACLPE----------WEDGHFYLAKYYDKLMPMVTDNK-
1950 1960 1970 1980 1990
1820 1830 1840 1850 1860 1870
pF1KB1 KLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSK
..:. :: .
XP_011 -------------------------------------------------MEKQ--GDLIR
2000
1880 1890 1900 1910 1920 1930
pF1KB1 TLLMYTVPAVQGFFRSISLSRGNNL--QDTLRVLTLWFDYGHWPDVNEALVEGVKAIQID
.... : :: :. ::.. :. :.::::.::: .:: .
XP_011 YIVLH-------FGRS--LQYGNQFIYQSMPRMLTLWLDYG------------TKAYE--
2010 2020 2030 2040
1940 1950 1960 1970 1980 1990
pF1KB1 TWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANK
: .. .: : :. :. .:.:. . . .: . :: ..
XP_011 -WEKA-----GRSD-------RV--QMRNDLGKINKVITEHTNYLAPYQFLTA----FSQ
2050 2060 2070 2080
2000 2010 2020 2030 2040 2050
pF1KB1 ILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEP
... .: ::. : ..: . .: . :: . .:. . : :. :.:.
XP_011 LISRIC-HSHDEVFVVLMEIIAKVFLAYPQQAMWM--MTAVSKSSYPMR-VNRCKEILN-
2090 2100 2110 2120 2130
2060 2070 2080 2090 2100 2110
pF1KB1 LHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISK
.:. . ..:.. . . : . : : : . .:. . :. . : :. ..:
XP_011 -KAIHMK--KSLEKFVGDATRLTDKL--LELCNKPV-DGSSSTLS----MSTH-FKMLKK
2140 2150 2160 2170 2180
2120 2130 2140 2150 2160
pF1KB1 QLPQLTSLELQYVSPKLLMCRDLE--LAVPGTYDPNQPI----IRIQSIAPSLQVITSKQ
. . : :. . . .: : :.. ... ..:. : .. .....: :
XP_011 LVEEATFSEI-LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQ
2190 2200 2210 2220 2230 2240
2170 2180 2190 2200 2210 2220
pF1KB1 RPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAV
.:.:..: ::.:. .... : ..:::.: :.:.. .:.: : .: : :..: :. :::
XP_011 KPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAV
2250 2260 2270 2280 2290 2300
2230 2240 2250 2260 2270 2280
pF1KB1 IPLSTNSGLIGWVPHCDTLHALI-RDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEV
:::. . :.: :: . :. .. . :.:: . . : : : : :. .:..:
XP_011 IPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC--MLPKSAALS--EKLKV
2310 2320 2330 2340 2350 2360
2290 2300 2310 2320 2330 2340
pF1KB1 FEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLML
:.. . . . . :. :.. :. : :: :::::::::::::::: :...
XP_011 FREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILF
2370 2380 2390 2400 2410 2420
2350 2360 2370 2380 2390 2400
pF1KB1 DRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEV
: :.:. .:.::. :. . : : :: .:::::. ..:.: : .: .: .:...:..
XP_011 DSLTGECVHVDFNCLFNKGETFE-VPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRL
2430 2440 2450 2460 2470 2480
2410 2420 2430 2440 2450 2460
pF1KB1 LREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEP
.:.... .:.::..:..:::..: . .::.... :
XP_011 MRDQREPLMSVLKTFLHDPLVEW---SKPVKGHSKA-----------------------P
2490 2500 2510
2470 2480 2490 2500 2510 2520
pF1KB1 AHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVE
.. :: .: :. .. . : .. .: . ..:...:: .: . .:.
XP_011 LNE-TGEVVNEKAKTHVLD--------IEQRLQGVIKTRNRVTGLPLS------IEGHVH
2520 2530 2540 2550
2530 2540
pF1KB1 LLIKQATSHENLCQCYIGWCPFW
::..::... ::: :.:: :.
XP_011 YLIQEATDENLLCQMYLGWTPYM
2560 2570 2580
>>NP_001175 (OMIM: 210600,601215,614564) serine/threonin (2644 aa)
initn: 928 init1: 235 opt: 625 Z-score: 666.2 bits: 137.5 E(85289): 2.3e-30
Smith-Waterman score: 749; 24.1% identity (51.2% similar) in 1192 aa overlap (1389-2548:1647-2643)
1360 1370 1380 1390 1400 1410
pF1KB1 NLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKA-LHYKE-LEFQKGPTPAILESL
. .::..: .:.. . .: : :
NP_001 MVSTVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFL
1620 1630 1640 1650 1660 1670
1420 1430 1440 1450 1460 1470
pF1KB1 ISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPEL
.. ...:...::: : :. : .:.: .:: . ::. .. . :.
NP_001 QKLYAAMHEPDGVAGV-SAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIH
1680 1690 1700 1710 1720 1730
1480 1490 1500 1510 1520 1530
pF1KB1 MLGRMRCLEALGEWGQLHQQCCEKWTLVN-DETQAKMARMAAAAAWGLGQWDSMEEYTCM
. : .. . .::. . . : . . .: .: .. . . ::: :.::: .:.:
NP_001 YHGVVKSMLGLGQLSTVITQV--NGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAA
1740 1750 1760 1770 1780 1790
1540 1550 1560 1570 1580
pF1KB1 IPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARD---LLDAE----LTAMAGE--SYSRA
:: . : : :.: .. : : :. :: :.: . : ::.:.
NP_001 ------DGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRG
1800 1810 1820 1830 1840
1590 1600 1610 1620 1630 1640
pF1KB1 YGAMVSCHMLSELEEVIQ--YKLVP-ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLV
: .: ::: :::. :. .. : . . : ::. : . . :: .: .
NP_001 YEYIVRLHMLCELEHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRAL
1850 1860 1870 1880 1890 1900
1650 1660 1670 1680 1690
pF1KB1 VS----P-HEDM--RTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQV
.: : ...: . ::. : . :.:. :...: :.. :: ..
NP_001 LSLNKRPDYNEMVGECWLQSARVARKAGHHQTAYNAL---LNAGESRL---------AEL
1910 1920 1930 1940 1950
1700 1710 1720 1730 1740 1750
pF1KB1 TYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGE
: .:. : :. : . ..:. .. . .. . . . .: .: .:.
NP_001 YVERAKWLWS---KGDVHQALI----VLQKGVELCFPENETPPEGKNMLIHGRAMLLVGR
1960 1970 1980 1990 2000
1760 1770 1780 1790 1800 1810
pF1KB1 WQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHY-KHQNQARDEKK
.. . ... ..: : . .: . : .: . .: : . .. :.:
NP_001 FMEETANFESNAIMKKYKDVTACLPE----------WEDGHFYLAKYYDKLMPMVTDNK-
2010 2020 2030 2040 2050
1820 1830 1840 1850 1860 1870
pF1KB1 KLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSK
..:. :: .
NP_001 -------------------------------------------------MEKQ--GDLIR
2060
1880 1890 1900 1910 1920 1930
pF1KB1 TLLMYTVPAVQGFFRSISLSRGNNL--QDTLRVLTLWFDYGHWPDVNEALVEGVKAIQID
.... : :: :. ::.. :. :.::::.::: .:: .
NP_001 YIVLH-------FGRS--LQYGNQFIYQSMPRMLTLWLDYG------------TKAYE--
2070 2080 2090 2100
1940 1950 1960 1970 1980 1990
pF1KB1 TWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANK
: .. .: : :. :. .:.:. . . .: . :: ..
NP_001 -WEKA-----GRSD-------RV--QMRNDLGKINKVITEHTNYLAPYQFLTA----FSQ
2110 2120 2130 2140
2000 2010 2020 2030 2040 2050
pF1KB1 ILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEP
... .: ::. : ..: . .: . :: . .:. . : :. :.:.
NP_001 LISRIC-HSHDEVFVVLMEIIAKVFLAYPQQAMWM--MTAVSKSSYPMR-VNRCKEILN-
2150 2160 2170 2180 2190
2060 2070 2080 2090 2100 2110
pF1KB1 LHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISK
.:. . ..:.. . . : . : : : . .:. . :. . : :. ..:
NP_001 -KAIHMK--KSLEKFVGDATRLTDKL--LELCNKPV-DGSSSTLS----MSTH-FKMLKK
2200 2210 2220 2230 2240
2120 2130 2140 2150 2160
pF1KB1 QLPQLTSLELQYVSPKLLMCRDLE--LAVPGTYDPNQPI----IRIQSIAPSLQVITSKQ
. . : :. . . .: : :.. ... ..:. : .. .....: :
NP_001 LVEEATFSEI-LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQ
2250 2260 2270 2280 2290 2300
2170 2180 2190 2200 2210 2220
pF1KB1 RPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAV
.:.:..: ::.:. .... : ..:::.: :.:.. .:.: : .: : :..: :. :::
NP_001 KPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAV
2310 2320 2330 2340 2350 2360
2230 2240 2250 2260 2270 2280
pF1KB1 IPLSTNSGLIGWVPHCDTLHALI-RDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEV
:::. . :.: :: . :. .. . :.:: . . : : : : :. .:..:
NP_001 IPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC--MLPKSAALS--EKLKV
2370 2380 2390 2400 2410 2420
2290 2300 2310 2320 2330 2340
pF1KB1 FEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLML
:.. . . . . :. :.. :. : :: :::::::::::::::: :...
NP_001 FREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILF
2430 2440 2450 2460 2470 2480
2350 2360 2370 2380 2390 2400
pF1KB1 DRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEV
: :.:. .:.::. :. . : : :: .:::::. ..:.: : .: .: .:...:..
NP_001 DSLTGECVHVDFNCLFNKGETFE-VPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRL
2490 2500 2510 2520 2530 2540
2410 2420 2430 2440 2450 2460
pF1KB1 LREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEP
.:.... .:.::..:..:::..: . .::.... :
NP_001 MRDQREPLMSVLKTFLHDPLVEW---SKPVKGHSKA-----------------------P
2550 2560 2570
2470 2480 2490 2500 2510 2520
pF1KB1 AHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVE
.. :: .: :. .. . : .. .: . ..:...:: .: . .:.
NP_001 LNE-TGEVVNEKAKTHVLD--------IEQRLQGVIKTRNRVTGLPLS------IEGHVH
2580 2590 2600 2610 2620
2530 2540
pF1KB1 LLIKQATSHENLCQCYIGWCPFW
::..::... ::: :.:: :.
NP_001 YLIQEATDENLLCQMYLGWTPYM
2630 2640
>>XP_011511226 (OMIM: 210600,601215,614564) PREDICTED: s (2646 aa)
initn: 928 init1: 235 opt: 625 Z-score: 666.2 bits: 137.5 E(85289): 2.3e-30
Smith-Waterman score: 749; 24.1% identity (51.2% similar) in 1192 aa overlap (1389-2548:1649-2645)
1360 1370 1380 1390 1400 1410
pF1KB1 NLAEFMEHSDKGPLPLRDDNGIVLLGERAAKCRAYAKA-LHYKE-LEFQKGPTPAILESL
. .::..: .:.. . .: : :
XP_011 MVSTVDYEDYQSVTRFLDLIPQDTLAVASFRSKAYTRAVMHFESFITEKKQNIQEHLGFL
1620 1630 1640 1650 1660 1670
1420 1430 1440 1450 1460 1470
pF1KB1 ISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWEDALVAYDKKMDTNKDDPEL
.. ...:...::: : :. : .:.: .:: . ::. .. . :.
XP_011 QKLYAAMHEPDGVAGV-SAIRKAEPSLKEQILEHESLGLLRDATACYDRAIQLEPDQIIH
1680 1690 1700 1710 1720 1730
1480 1490 1500 1510 1520 1530
pF1KB1 MLGRMRCLEALGEWGQLHQQCCEKWTLVN-DETQAKMARMAAAAAWGLGQWDSMEEYTCM
. : .. . .::. . . : . . .: .: .. . . ::: :.::: .:.:
XP_011 YHGVVKSMLGLGQLSTVITQV--NGVHANRSEWTDELNTYRVEAAWKLSQWDLVENYLAA
1740 1750 1760 1770 1780 1790
1540 1550 1560 1570 1580
pF1KB1 IPRDTHDGAFYRAVLALHQDLFSLAQQCIDKARD---LLDAE----LTAMAGE--SYSRA
:: . : : :.: .. : : :. :: :.: . : ::.:.
XP_011 ------DGKSTTWSVRLGQLLLSAKKRDITAFYDSLKLVRAEQIVPLSAASFERGSYQRG
1800 1810 1820 1830 1840
1590 1600 1610 1620 1630 1640
pF1KB1 YGAMVSCHMLSELEEVIQ--YKLVP-ERREIIRQIWWERLQGCQRIVEDWQKILMVRSLV
: .: ::: :::. :. .. : . . : ::. : . . :: .: .
XP_011 YEYIVRLHMLCELEHSIKPLFQHSPGDSSQEDSLNWVARLEMTQNSYRAKEPILALRRAL
1850 1860 1870 1880 1890 1900
1650 1660 1670 1680 1690
pF1KB1 VS----P-HEDM--RTWLKYASLCGKSGRLALAHKTLVLLLGVDPSRQLDHPLPTVHPQV
.: : ...: . ::. : . :.:. :...: :.. :: ..
XP_011 LSLNKRPDYNEMVGECWLQSARVARKAGHHQTAYNAL---LNAGESRL---------AEL
1910 1920 1930 1940 1950
1700 1710 1720 1730 1740 1750
pF1KB1 TYAYMKNMWKSARKIDAFQHMQHFVQTMQQQAQHAIATEDQQHKQELHKLMARCFLKLGE
: .:. : :. : . ..:. .. . .. . . . .: .: .:.
XP_011 YVERAKWLWS---KGDVHQALI----VLQKGVELCFPENETPPEGKNMLIHGRAMLLVGR
1960 1970 1980 1990 2000 2010
1760 1770 1780 1790 1800 1810
pF1KB1 WQLNLQGINESTIPKVLQYYSAATEHDRSWYKAWHAWAVMNFEAVLHY-KHQNQARDEKK
.. . ... ..: : . .: . : .: . .: : . .. :.:
XP_011 FMEETANFESNAIMKKYKDVTACLPE----------WEDGHFYLAKYYDKLMPMVTDNK-
2020 2030 2040 2050
1820 1830 1840 1850 1860 1870
pF1KB1 KLRHASGANITNATTAATTAATATTTASTEGSNSESEAESTENSPTPSPLQKKVTEDLSK
..:. :: .
XP_011 -------------------------------------------------MEKQ--GDLIR
2060
1880 1890 1900 1910 1920 1930
pF1KB1 TLLMYTVPAVQGFFRSISLSRGNNL--QDTLRVLTLWFDYGHWPDVNEALVEGVKAIQID
.... : :: :. ::.. :. :.::::.::: .:: .
XP_011 YIVLH-------FGRS--LQYGNQFIYQSMPRMLTLWLDYG------------TKAYE--
2070 2080 2090 2100
1940 1950 1960 1970 1980 1990
pF1KB1 TWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKSTTTARHNAANK
: .. .: : :. :. .:.:. . . .: . :: ..
XP_011 -WEKA-----GRSD-------RV--QMRNDLGKINKVITEHTNYLAPYQFLTA----FSQ
2110 2120 2130 2140
2000 2010 2020 2030 2040 2050
pF1KB1 ILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFGERNVKGMFEVLEP
... .: ::. : ..: . .: . :: . .:. . : :. :.:.
XP_011 LISRIC-HSHDEVFVVLMEIIAKVFLAYPQQAMWM--MTAVSKSSYPMR-VNRCKEILN-
2150 2160 2170 2180 2190 2200
2060 2070 2080 2090 2100 2110
pF1KB1 LHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISK
.:. . ..:.. . . : . : : : . .:. . :. . : :. ..:
XP_011 -KAIHMK--KSLEKFVGDATRLTDKL--LELCNKPV-DGSSSTLS----MSTH-FKMLKK
2210 2220 2230 2240 2250
2120 2130 2140 2150 2160
pF1KB1 QLPQLTSLELQYVSPKLLMCRDLE--LAVPGTYDPNQPI----IRIQSIAPSLQVITSKQ
. . : :. . . .: : :.. ... ..:. : .. .....: :
XP_011 LVEEATFSEI-LIPLQSVMIPTLPSILGTHANHASHEPFPGHWAYIAGFDDMVEILASLQ
2260 2270 2280 2290 2300
2170 2180 2190 2200 2210 2220
pF1KB1 RPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAV
.:.:..: ::.:. .... : ..:::.: :.:.. .:.: : .: : :..: :. :::
XP_011 KPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKDAESRRRELHIRTYAV
2310 2320 2330 2340 2350 2360
2230 2240 2250 2260 2270 2280
pF1KB1 IPLSTNSGLIGWVPHCDTLHALI-RDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKVEV
:::. . :.: :: . :. .. . :.:: . . : : : : :. .:..:
XP_011 IPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYMTGKELRQC--MLPKSAALS--EKLKV
2370 2380 2390 2400 2410 2420
2290 2300 2310 2320 2330 2340
pF1KB1 FEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLML
:.. . . . . :. :.. :. : :: :::::::::::::::: :...
XP_011 FREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILF
2430 2440 2450 2460 2470 2480
2350 2360 2370 2380 2390 2400
pF1KB1 DRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEV
: :.:. .:.::. :. . : : :: .:::::. ..:.: : .: .: .:...:..
XP_011 DSLTGECVHVDFNCLFNKGETFE-VPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRL
2490 2500 2510 2520 2530 2540
2410 2420 2430 2440 2450 2460
pF1KB1 LREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDSYSAGQSVEILDGVELGEP
.:.... .:.::..:..:::..: . .::.... :
XP_011 MRDQREPLMSVLKTFLHDPLVEW---SKPVKGHSKA-----------------------P
2550 2560 2570
2470 2480 2490 2500 2510 2520
pF1KB1 AHKKTGTTVPESIHSFIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSHDDTLDVPTQVE
.. :: .: :. .. . : .. .: . ..:...:: .: . .:.
XP_011 LNE-TGEVVNEKAKTHVLD--------IEQRLQGVIKTRNRVTGLPLS------IEGHVH
2580 2590 2600 2610 2620
2530 2540
pF1KB1 LLIKQATSHENLCQCYIGWCPFW
::..::... ::: :.:: :.
XP_011 YLIQEATDENLLCQMYLGWTPYM
2630 2640
2549 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 11:47:43 2016 done: Thu Nov 3 11:47:46 2016
Total Scan time: 16.620 Total Display time: 1.540
Function used was FASTA [36.3.4 Apr, 2011]