FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0174, 1358 aa
  1>>>pF1KB0174 1358 - 1358 aa - 1358 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.1870+/-0.00049; mu= 15.0694+/- 0.030
 mean_var=193.1733+/-42.621, 0's: 0 Z-trim(114.1): 92  B-trim: 1080 in 1/52
 Lambda= 0.092279
 statistics sampled from 23700 (23766) to 23700 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.279), width:  16
 Scan time: 14.030

The best scores are:                                      opt bits E(85289)
NP_055417 (OMIM: 602610) phosphoinositide 3-kinase (1358) 9035 1217.4       0


>>NP_055417 (OMIM: 602610) phosphoinositide 3-kinase reg  (1358 aa)
 initn: 9035 init1: 9035 opt: 9035  Z-score: 6512.4  bits: 1217.4 E(85289):    0
Smith-Waterman score: 9035; 100.0% identity (100.0% similar) in 1358 aa overlap (1-1358:1-1358)

               10        20        30        40        50        60
pF1KB0 MGNQLAGIAPSQILSVESYFSDIHDFEYDKSLGSTRFFKVARAKHREGLVVVKVFAIQDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGNQLAGIAPSQILSVESYFSDIHDFEYDKSLGSTRFFKVARAKHREGLVVVKVFAIQDP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 TLPLTSYKQELEELKIRLNSAQNCLPFQKASEKASEKAAMLFRQYVRDNLYDRISTRPFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TLPLTSYKQELEELKIRLNSAQNCLPFQKASEKASEKAAMLFRQYVRDNLYDRISTRPFL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 NNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLPEDNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLPEDNP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 ADFNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPLVDLNSNQRTRGELKRAMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADFNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPLVDLNSNQRTRGELKRAMD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 IFSAGCVIAELFTEGVPLFDLSQLLAYRNGHFFPEQVLNKIEDHSIRELVTQMIHREPDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IFSAGCVIAELFTEGVPLFDLSQLLAYRNGHFFPEQVLNKIEDHSIRELVTQMIHREPDK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 RLEAEDYLKQQRGNAFPEIFYTFLQPYMAQFAKETFLSADERILVIRKDLGNIIHNLCGH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RLEAEDYLKQQRGNAFPEIFYTFLQPYMAQFAKETFLSADERILVIRKDLGNIIHNLCGH
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 DLPEKAEGEPKENGLVILVSVITSCLQTLKYCDSKLAALELILHLAPRLSVEILLDRITP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLPEKAEGEPKENGLVILVSVITSCLQTLKYCDSKLAALELILHLAPRLSVEILLDRITP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 YLLHFSNDSVPRVRAEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YLLHFSNDSVPRVRAEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRL
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 AYAENIALLAETALRFLELVQLKNLNMENDPNNEEIDEVTHPNGNYDTELQALHEMVQQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AYAENIALLAETALRFLELVQLKNLNMENDPNNEEIDEVTHPNGNYDTELQALHEMVQQK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 VVTLLSDPENIVKQTLMENGITRLCVFFGRQKANDVLLSHMITFLNDKNDWHLRGAFFDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VVTLLSDPENIVKQTLMENGITRLCVFFGRQKANDVLLSHMITFLNDKNDWHLRGAFFDS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 IVGVAAYVGWQSSSILKPLLQQGLSDAEEFVIVKALYALTCMCQLGLLQKPHVYEFASDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IVGVAAYVGWQSSSILKPLLQQGLSDAEEFVIVKALYALTCMCQLGLLQKPHVYEFASDI
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 APFLCHPNLWIRYGAVGFITVVARQISTADVYCKLMPYLDPYITQPIIQIERKLVLLSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 APFLCHPNLWIRYGAVGFITVVARQISTADVYCKLMPYLDPYITQPIIQIERKLVLLSVL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 KEPVSRSIFDYALRSKDITSLFRHLHMRQKKRNGSLPDCPPPEDPAIAQLLKKLLSQGMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEPVSRSIFDYALRSKDITSLFRHLHMRQKKRNGSLPDCPPPEDPAIAQLLKKLLSQGMT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 EEEEDKLLALKDFMMKSNKAKANIVDQSHLHDSSQKGVIDLAALGITGRQVDLVKTKQEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEEEDKLLALKDFMMKSNKAKANIVDQSHLHDSSQKGVIDLAALGITGRQVDLVKTKQEP
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 DDKRARKHVKQDSNVNEEWKSMFGSLDPPNMPQALPKGSDQEVIQTGKPPRSESSAGICV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DDKRARKHVKQDSNVNEEWKSMFGSLDPPNMPQALPKGSDQEVIQTGKPPRSESSAGICV
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 PLSTSSQVPEVTTVQNKKPVIPVLSSTILPSTYQIRITTCKTELQQLIQQKREQCNAERI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PLSTSSQVPEVTTVQNKKPVIPVLSSTILPSTYQIRITTCKTELQQLIQQKREQCNAERI
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 AKQMMENAEWESKPPPPGWRPKGLLVAHLHEHKSAVNRIRVSDEHSLFATCSNDGTVKIW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AKQMMENAEWESKPPPPGWRPKGLLVAHLHEHKSAVNRIRVSDEHSLFATCSNDGTVKIW
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 NSQKMEGKTTTTRSILTYSRIGGRVKTLTFCQGSHYLAIASDNGAVQLLGIEASKLPKSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSQKMEGKTTTTRSILTYSRIGGRVKTLTFCQGSHYLAIASDNGAVQLLGIEASKLPKSP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 KIHPLQSRILDQKEDGCVVDMHHFNSGAQSVLAYATVNGSLVGWDLRSSSNAWTLKHDLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KIHPLQSRILDQKEDGCVVDMHHFNSGAQSVLAYATVNGSLVGWDLRSSSNAWTLKHDLK
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 SGLITSFAVDIHQCWLCIGTSSGTMACWDMRFQLPISSHCHPSRARIRRLSMHPLYQSWV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGLITSFAVDIHQCWLCIGTSSGTMACWDMRFQLPISSHCHPSRARIRRLSMHPLYQSWV
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 IAAVQGNNEVSMWDMETGDRRFTLWASSAPPLSELQPSPHSVHGIYCSPADGNPILLTAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IAAVQGNNEVSMWDMETGDRRFTLWASSAPPLSELQPSPHSVHGIYCSPADGNPILLTAG
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 SDMKIRFWDLAYPERSYVVAGSTSSPSVSYYRKIIEGTEVVQEIQNKQKVGPSDDTPRRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SDMKIRFWDLAYPERSYVVAGSTSSPSVSYYRKIIEGTEVVQEIQNKQKVGPSDDTPRRG
             1270      1280      1290      1300      1310      1320

             1330      1340      1350        
pF1KB0 PESLPVGHHDIITDVATFQTTQGFIVTASRDGIVKVWK
       ::::::::::::::::::::::::::::::::::::::
NP_055 PESLPVGHHDIITDVATFQTTQGFIVTASRDGIVKVWK
             1330      1340      1350        




1358 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 11:41:59 2016 done: Thu Nov  3 11:42:01 2016
 Total Scan time: 14.030 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]