Result of FASTA (ccds) for
pF1KB0067
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0067, 2442 aa
1>>>pF1KB0067 2442 - 2442 aa - 2442 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.6833+/-0.00122; mu= -19.2753+/- 0.073
mean_var=695.3778+/-143.363, 0's: 0 Z-trim(116.3): 100 B-trim: 0 in 0/55
Lambda= 0.048637
statistics sampled from 16780 (16863) to 16780 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.518), width: 16
Scan time: 7.580
The best scores are: opt bits E(32554)
CCDS10509.1 CREBBP gene_id:1387|Hs108|chr16 (2442) 16860 1200.1 0
CCDS45399.1 CREBBP gene_id:1387|Hs108|chr16 (2404) 13906 992.8 0
CCDS14010.1 EP300 gene_id:2033|Hs108|chr22 (2414) 6812 495.0 1.8e-138
>>CCDS10509.1 CREBBP gene_id:1387|Hs108|chr16 (2442 aa)
initn: 16860 init1: 16860 opt: 16860 Z-score: 6409.7 bits: 1200.1 E(32554): 0
Smith-Waterman score: 16860; 100.0% identity (100.0% similar) in 2442 aa overlap (1-2442:1-2442)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::
CCDS10 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2410 2420 2430 2440
>>CCDS45399.1 CREBBP gene_id:1387|Hs108|chr16 (2404 aa)
initn: 13889 init1: 13889 opt: 13906 Z-score: 5289.6 bits: 992.8 E(32554): 0
Smith-Waterman score: 16485; 98.4% identity (98.4% similar) in 2442 aa overlap (1-2442:1-2404)
10 20 30 40 50 60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
:::::::::::::::::::::::::::::::::::::::::::::.
CCDS45 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQA--------------
370 380 390 400
430 440 450 460 470 480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
::::::::::::::::::::::::::::::::::::
CCDS45 ------------------------ILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
410 420 430 440
490 500 510 520 530 540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
750 760 770 780 790 800
850 860 870 880 890 900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
810 820 830 840 850 860
910 920 930 940 950 960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
1350 1360 1370 1380 1390 1400
1450 1460 1470 1480 1490 1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
1410 1420 1430 1440 1450 1460
1510 1520 1530 1540 1550 1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
1590 1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
1650 1660 1670 1680 1690 1700
1750 1760 1770 1780 1790 1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
1710 1720 1730 1740 1750 1760
1810 1820 1830 1840 1850 1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
1770 1780 1790 1800 1810 1820
1870 1880 1890 1900 1910 1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
1830 1840 1850 1860 1870 1880
1930 1940 1950 1960 1970 1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
1890 1900 1910 1920 1930 1940
1990 2000 2010 2020 2030 2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
1950 1960 1970 1980 1990 2000
2050 2060 2070 2080 2090 2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
2010 2020 2030 2040 2050 2060
2110 2120 2130 2140 2150 2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
2070 2080 2090 2100 2110 2120
2170 2180 2190 2200 2210 2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
2130 2140 2150 2160 2170 2180
2230 2240 2250 2260 2270 2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
2190 2200 2210 2220 2230 2240
2290 2300 2310 2320 2330 2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
2250 2260 2270 2280 2290 2300
2350 2360 2370 2380 2390 2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
2310 2320 2330 2340 2350 2360
2410 2420 2430 2440
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
::::::::::::::::::::::::::::::::::::::::::
CCDS45 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
2370 2380 2390 2400
>>CCDS14010.1 EP300 gene_id:2033|Hs108|chr22 (2414 aa)
initn: 7325 init1: 3547 opt: 6812 Z-score: 2599.4 bits: 495.0 E(32554): 1.8e-138
Smith-Waterman score: 9748; 60.9% identity (78.5% similar) in 2517 aa overlap (1-2431:1-2400)
10 20 30 40 50
pF1KB0 MAENLLD-GPPNPKRAKLSSPGFSAN--DSTDFGSLFDLENDLPDELIPNGGELGLLNSG
::::... :::. :: :::::..::. :.::::::::::.::::::: :. :::: :.:
CCDS14 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG
10 20 30 40 50
60 70 80 90 100
pF1KB0 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN
. .: ::::::::::::::.::. ..: :.:. : : .:.: .
CCDS14 DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG-----P---GQVMASQAQQS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB0 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT
: ... ...: :::..:. ..:.. . .::::. . .:. .:. .:
CCDS14 SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ
120 130 140 150 160
170 180 190 200 210 220
pF1KB0 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT
: . :::..: ::.: ...:.... . ::::::.:: :::: .: ::.
CCDS14 PAMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSIGA-GRGR-QNMQYPN
170 180 190 200
230 240 250 260 270 280
pF1KB0 PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM
:.: :.....:.: : : :::: :..:: : :::. .: .:.:.:..: :: .
CCDS14 PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB0 GATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQ-----MQTSVGIVPT-QAIAT
::.:.. :. .: . :.: : : : . ..:::.: .: ..:. :....
CCDS14 GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGS
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB0 GP-TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG
: :::::::::::::::::::::::::::::::::: :.::::::::::::::::::.:
CCDS14 GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG
330 340 350 360 370 380
410 420 430 440 450 460
pF1KB0 KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTIL-GSPASGIQNTIGSV
:.:::::::::::::::::::::::::::::::::.:::::: :: :.:. :. : .:.
CCDS14 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPV-GLGNP-SSL
390 400 410 420 430 440
470 480 490 500 510
pF1KB0 GTGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQPQTQLQPQVPGQQPAQP-QTHQQM
:.:::.: .::. . :::::..:::::::::: .:: :: : :. .:: :: :. : :
CCDS14 GVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGM
450 460 470 480 490 500
520 530 540 550 560 570
pF1KB0 RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP
: .. .. .::.. ::. . : :.:.:.: : ..... ::.: :..... .:. .:
CCDS14 RPMSNMSASPMGV-NGGVGV--QTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMP
510 520 530 540 550
580 590 600 610 620 630
pF1KB0 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG
::: ::.::.:: ::: .:::::.:::::::::::::::::::::::::::::::.::::
CCDS14 TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG
560 570 580 590 600 610
640 650 660 670 680 690
pF1KB0 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQ
:::::::.: ::::::::::::::::::::::.::.::..: : .. . .: : . :
CCDS14 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQ
620 630 640 650 660 670
700 710 720 730 740 750
pF1KB0 AQPVRPPNGPLSLP-VNRMQV-SQGMNSFNPMS----LGNVQLPQAPMGPRAASPMNHSV
:: :::: : . : .: .: : ..:.: .:.... : :. :: . :..:
CCDS14 PQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHG
680 690 700 710 720 730
760 770 780 790 800
pF1KB0 QMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GAMSVG
:. . :.. : :. .: :: :: : :.:::::.::::.. .. ..
CCDS14 QLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNVTNIP
740 750 760 770 780
810 820 830 840 850 860
pF1KB0 MGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH---PTPPPASTAA
.. .:. :::.:. ... : .:. : :.:.. :: . : :: :.: :. : .
CCDS14 LAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPT
790 800 810 820 830 840
870 880 890 900 910 920
pF1KB0 GM---PSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA
::. ::. : : :. :: :. : . ..:. : : ..:. :: :: .
CCDS14 PHHTPPSIGAQQPPATTIPAPV-PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS
850 860 870 880 890 900
930 940 950 960 970
pF1KB0 AQAQVTP-QPQTPVQPPSVATPQSSQQQPT-PVHAQPPGTPLSQAAASIDNRVPTPSSVA
: . ::: :: : . .: :: :. :.::::: :.::...: .: :..
CCDS14 LPAAPSADQPQQ--QPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTS
910 920 930 940 950
980 990 1000 1010 1020 1030
pF1KB0 SAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIA
:.:.::: . : :.: :.. : .:.:... .: ::.. :. .
CCDS14 STEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADT--QP------EDIS-------ESKVE
960 970 980 990 1000
1040 1050 1060 1070 1080 1090
pF1KB0 EQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLE
. : : :..:.. :.:.:.::::.. :......: .:.: .::::::::::::::::::
CCDS14 DCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLE
1010 1020 1030 1040 1050 1060
1100 1110 1120 1130 1140 1150
pF1KB0 ALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWL
:::::::::::::::::::::::::::::::.:::::::::::::::::::::::::.::
CCDS14 ALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWL
1070 1080 1090 1100 1110 1120
1160 1170 1180 1190 1200 1210
pF1KB0 MFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLC
:::::::::::::::::.::::.::::::::::::::::::::: :::::::::::::::
CCDS14 MFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLC
1130 1140 1150 1160 1170 1180
1220 1230 1240 1250 1260 1270
pF1KB0 TIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEP
::::::.:::::::::::::::.:::::.:.::::::::::::.:.:: :.::::::::
CCDS14 TIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPEL
1190 1200 1210 1220 1230 1240
1280 1290 1300 1310 1320 1330
pF1KB0 FVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLE
::.: :::::::::::::..::::.:::::.::::..: ::::::::::: .::::. ::
CCDS14 FVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLE
1250 1260 1270 1280 1290 1300
1340 1350 1360 1370 1380 1390
pF1KB0 DRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAF
.::: :::::::::.::: :::: .::::::::::::.::::::::.:::::::::::::
CCDS14 NRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAF
1310 1320 1330 1340 1350 1360
1400 1410 1420 1430 1440 1450
pF1KB0 EEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLE
:::::::.:::::::::::::::::: ::::::::::.:::::.::::::::::::::::
CCDS14 EEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLE
1370 1380 1390 1400 1410 1420
1460 1470 1480 1490 1500 1510
pF1KB0 YVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDY
:::::::.::::::::::::::::::::::::::::::::::::::::::: .:::.:::
CCDS14 YVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDY
1430 1440 1450 1460 1470 1480
1520 1530 1540 1550 1560 1570
pF1KB0 KDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQ
:::::::::::::::::::::::::::::::::::::::::::::.::.:. .:.:. ..
CCDS14 KDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTS-NESTDVTK
1490 1500 1510 1520 1530 1540
1580 1590 1600 1610 1620 1630
pF1KB0 GDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHA
::::::::::::::.:::::.::.:::::.::::::::::::::::::::::::::.: :
CCDS14 GDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIA
1550 1560 1570 1580 1590 1600
1640 1650 1660 1670 1680 1690
pF1KB0 GPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQG
::. :.::::::::::. :::::::::::::::::: :::::::..:::.:::::::::.
CCDS14 GPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQS
1610 1620 1630 1640 1650 1660
1700 1710 1720 1730 1740 1750
pF1KB0 QDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEP
:::::::::::::::::::::::::::::::.:::::.: ::: : :::::::...:
CCDS14 QDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAA
1670 1680 1690 1700 1710 1720
1760 1770 1780 1790 1800 1810
pF1KB0 QSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVC
..:: .:::::::::::::::::::::::::::::::::::::::::::::::::::.:
CCDS14 ATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPIC
1730 1740 1750 1760 1770 1780
1820 1830 1840 1850 1860 1870
pF1KB0 KQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNV--
::::::::::::::::::::::::::::.::::::.::::::::..:::::.:. .:
CCDS14 KQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVG
1790 1800 1810 1820 1830 1840
1880 1890 1900 1910 1920 1930
pF1KB0 PQQSLPSPTSAPPGTPT-QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG
::.::::: : : ::: :::.::::::: .::::.: . : : . ::: :: :
CCDS14 QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP---PYLPRTQAAGPVSQG
1850 1860 1870 1880 1890
1940 1950 1960 1970 1980
pF1KB0 KPTSQV--PAPPPPAQPP-----PAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMG
: ..:: :.:: :::: ::::: : ::.: :. :... .:.: . : . :
CCDS14 KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR--PIQHQM-
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KB0 TPGSQMAPVSLNVPRPNQ-VSGPVMPSM-PPGQWQQAP-----LPQ-QQPMPGLPRPVIS
: . :::...: : .. :: . :.: : :. :: : ::: :: . :.:::..
CCDS14 PPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMM
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090
pF1KB0 MQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQVLNILKS
:: : : . ...: : ..: .:::.:::::.::::: ::::::.::..
CCDS14 SVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHA
2020 2030 2040 2050 2060 2070
2100 2110 2120 2130 2140
pF1KB0 NPQLMAAFIKQRTAKYVANQPGMQP-QPGL-QSQPGMQP-----QPGMHQQPSLQNLNAM
::::.:::::::.:::. ..: : :::. :.:::.:: : :.:..:..::.: :
CCDS14 NPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPM
2080 2090 2100 2110 2120 2130
2150 2160 2170 2180 2190
pF1KB0 QAGVPRPGVP---PQQQ---AMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQ
:::: : :.: :::: :::..::.: .: :: :: .: :.:..::::
CCDS14 QAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN-MN--HN----TMPSQFRDILRRQ---
2140 2150 2160 2170 2180
2200 2210 2220 2230 2240 2250
pF1KB0 QQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS
:..:::::: .. :.. :::.:.::::::: : ::: :::::::.:. .
CCDS14 -------QMMQQQQQQGAGPGIGPGMANHNQFQQPQGVG-YPP--QQQQRMQHHM----Q
2190 2200 2210 2220 2230
2260 2270 2280 2290 2300 2310
pF1KB0 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQH
.: : ..:::.::. : .:::.. ..: : :::.:::: .::: ::::::::::
CCDS14 QMQQ--GNMGQIGQLPQ-ALGAEAGASLQ-AYQQRLLQQQ-----MGSPVQPNPMSPQQH
2240 2250 2260 2270 2280
2320 2330 2340 2350 2360 2370
pF1KB0 MLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ
:: .: :. :: :::: .::::::::: :: ::::::::::::::::.::::::::::::
CCDS14 MLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQ
2290 2300 2310 2320 2330 2340
2380 2390 2400 2410 2420 2430
pF1KB0 TGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNT-PSRSAL----SSELSLVGDTTGDT
:.::::::....:. ..:::...:.:..:: :: . :. . : ...:.: :..
CCDS14 TSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNSDLN
2350 2360 2370 2380 2390 2400
2440
pF1KB0 LEKFVEGL
CCDS14 SNLSQSTLDIH
2410
2442 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:22:15 2016 done: Sun Nov 6 20:22:17 2016
Total Scan time: 7.580 Total Display time: 0.600
Function used was FASTA [36.3.4 Apr, 2011]