Result of FASTA (omim) for
pF1KB0023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0023, 2115 aa
1>>>pF1KB0023 2115 - 2115 aa - 2115 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.5455+/-0.000738; mu= -32.9504+/- 0.045
mean_var=843.8959+/-179.712, 0's: 0 Z-trim(118.1): 691 B-trim: 0 in 0/54
Lambda= 0.044150
statistics sampled from 29938 (30652) to 29938 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.359), width: 16
Scan time: 20.710
The best scores are: opt bits E(85289)
NP_006176 (OMIM: 164009,612376) nuclear mitotic ap (2115) 13255 862.2 0
XP_006718627 (OMIM: 164009,612376) PREDICTED: nucl (2115) 13255 862.2 0
XP_011543367 (OMIM: 164009,612376) PREDICTED: nucl (2119) 12094 788.3 0
XP_011543358 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543356 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543357 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543362 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543359 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543365 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543364 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543360 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543363 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543361 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_011543366 (OMIM: 164009,612376) PREDICTED: nucl (2133) 10843 708.6 1.9e-202
XP_016873319 (OMIM: 164009,612376) PREDICTED: nucl (2101) 9699 635.7 1.6e-180
XP_011543368 (OMIM: 164009,612376) PREDICTED: nucl (2101) 9699 635.7 1.6e-180
XP_016873320 (OMIM: 164009,612376) PREDICTED: nucl (2101) 9699 635.7 1.6e-180
NP_001273490 (OMIM: 164009,612376) nuclear mitotic (2101) 9699 635.7 1.6e-180
NP_009044 (OMIM: 190370) trichohyalin [Homo sapien (1943) 775 67.3 2e-09
NP_001305148 (OMIM: 609689) centrosome-associated (1810) 714 63.4 2.7e-08
XP_016883108 (OMIM: 609689) PREDICTED: centrosome- (1976) 714 63.4 2.9e-08
XP_016883107 (OMIM: 609689) PREDICTED: centrosome- (2198) 714 63.4 3.2e-08
XP_011526821 (OMIM: 609689) PREDICTED: centrosome- (2240) 714 63.4 3.2e-08
XP_011526820 (OMIM: 609689) PREDICTED: centrosome- (2319) 714 63.5 3.3e-08
XP_005260321 (OMIM: 609689) PREDICTED: centrosome- (2365) 714 63.5 3.4e-08
XP_006723754 (OMIM: 609689) PREDICTED: centrosome- (2442) 714 63.5 3.5e-08
XP_006723756 (OMIM: 609689) PREDICTED: centrosome- (2442) 714 63.5 3.5e-08
XP_006723755 (OMIM: 609689) PREDICTED: centrosome- (2442) 714 63.5 3.5e-08
XP_005260319 (OMIM: 609689) PREDICTED: centrosome- (2442) 714 63.5 3.5e-08
XP_006723753 (OMIM: 609689) PREDICTED: centrosome- (2442) 714 63.5 3.5e-08
NP_009117 (OMIM: 609689) centrosome-associated pro (2442) 714 63.5 3.5e-08
XP_006723757 (OMIM: 609689) PREDICTED: centrosome- (2404) 713 63.4 3.6e-08
XP_005260320 (OMIM: 609689) PREDICTED: centrosome- (2370) 711 63.3 3.8e-08
XP_011526819 (OMIM: 609689) PREDICTED: centrosome- (2355) 699 62.5 6.5e-08
XP_016883106 (OMIM: 609689) PREDICTED: centrosome- (2332) 694 62.2 8.1e-08
NP_002465 (OMIM: 132900,160745) myosin-11 isoform (1972) 682 61.4 1.2e-07
NP_001035203 (OMIM: 132900,160745) myosin-11 isofo (1979) 682 61.4 1.2e-07
XP_011520804 (OMIM: 132900,160745) PREDICTED: myos (1929) 681 61.3 1.2e-07
NP_074035 (OMIM: 132900,160745) myosin-11 isoform (1938) 681 61.3 1.2e-07
NP_001035202 (OMIM: 132900,160745) myosin-11 isofo (1945) 681 61.3 1.2e-07
XP_016878739 (OMIM: 132900,160745) PREDICTED: myos (1945) 681 61.3 1.2e-07
NP_079005 (OMIM: 600652,608568,614369) myosin-14 i (1995) 676 61.0 1.6e-07
XP_006723449 (OMIM: 600652,608568,614369) PREDICTE (2003) 676 61.0 1.6e-07
XP_011525625 (OMIM: 600652,608568,614369) PREDICTE (2003) 676 61.0 1.6e-07
NP_001070654 (OMIM: 600652,608568,614369) myosin-1 (2003) 676 61.0 1.6e-07
XP_011525623 (OMIM: 600652,608568,614369) PREDICTE (2035) 676 61.0 1.6e-07
NP_001139281 (OMIM: 600652,608568,614369) myosin-1 (2036) 676 61.0 1.6e-07
XP_011525622 (OMIM: 600652,608568,614369) PREDICTE (2043) 676 61.0 1.6e-07
XP_011529846 (OMIM: 117143,616051) PREDICTED: cent (2676) 670 60.7 2.6e-07
NP_001804 (OMIM: 117143,616051) centromere-associa (2701) 670 60.7 2.6e-07
>>NP_006176 (OMIM: 164009,612376) nuclear mitotic appara (2115 aa)
initn: 13255 init1: 13255 opt: 13255 Z-score: 4585.9 bits: 862.2 E(85289): 0
Smith-Waterman score: 13255; 100.0% identity (100.0% similar) in 2115 aa overlap (1-2115:1-2115)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB0 GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB0 GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB0 AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB0 ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB0 QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
2050 2060 2070 2080 2090 2100
2110
pF1KB0 AAIGATPRAKGKAKH
:::::::::::::::
NP_006 AAIGATPRAKGKAKH
2110
>>XP_006718627 (OMIM: 164009,612376) PREDICTED: nuclear (2115 aa)
initn: 13255 init1: 13255 opt: 13255 Z-score: 4585.9 bits: 862.2 E(85289): 0
Smith-Waterman score: 13255; 100.0% identity (100.0% similar) in 2115 aa overlap (1-2115:1-2115)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB0 LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB0 GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB0 GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB0 AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB0 ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB0 QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
2050 2060 2070 2080 2090 2100
2110
pF1KB0 AAIGATPRAKGKAKH
:::::::::::::::
XP_006 AAIGATPRAKGKAKH
2110
>>XP_011543367 (OMIM: 164009,612376) PREDICTED: nuclear (2119 aa)
initn: 12058 init1: 9615 opt: 12094 Z-score: 4186.2 bits: 788.3 E(85289): 0
Smith-Waterman score: 13084; 98.5% identity (98.5% similar) in 2133 aa overlap (1-2115:1-2119)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
:::::::::::::::::::::::::::::::::::::: ::::::::
XP_011 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVE--------------ELSKKLAD
1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSIT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITRH
1670 1680 1690 1700 1710 1720
1740 1750 1760 1770 1780
pF1KB0 ----------------SKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALMTIIPDLSPNNPLSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
1730 1740 1750 1760 1770 1780
1790 1800 1810 1820 1830 1840
pF1KB0 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
1790 1800 1810 1820 1830 1840
1850 1860 1870 1880 1890 1900
pF1KB0 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
1850 1860 1870 1880 1890 1900
1910 1920 1930 1940 1950 1960
pF1KB0 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
1910 1920 1930 1940 1950 1960
1970 1980 1990 2000 2010 2020
pF1KB0 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
1970 1980 1990 2000 2010 2020
2030 2040 2050 2060 2070 2080
pF1KB0 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
2030 2040 2050 2060 2070 2080
2090 2100 2110
pF1KB0 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
:::::::::::::::::::::::::::::::::
XP_011 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
2090 2100 2110
>>XP_011543358 (OMIM: 164009,612376) PREDICTED: nuclear (2133 aa)
initn: 13241 init1: 10798 opt: 10843 Z-score: 3755.6 bits: 708.6 E(85289): 1.9e-202
Smith-Waterman score: 13209; 99.2% identity (99.2% similar) in 2133 aa overlap (1-2115:1-2133)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSIT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITRH
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780
pF1KB0 ----------------SKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALMTIIPDLSPNNPLSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KB0 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KB0 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KB0 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KB0 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KB0 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
2050 2060 2070 2080 2090 2100
2090 2100 2110
pF1KB0 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
:::::::::::::::::::::::::::::::::
XP_011 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
2110 2120 2130
>>XP_011543356 (OMIM: 164009,612376) PREDICTED: nuclear (2133 aa)
initn: 13241 init1: 10798 opt: 10843 Z-score: 3755.6 bits: 708.6 E(85289): 1.9e-202
Smith-Waterman score: 13209; 99.2% identity (99.2% similar) in 2133 aa overlap (1-2115:1-2133)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSIT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITRH
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780
pF1KB0 ----------------SKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALMTIIPDLSPNNPLSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KB0 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KB0 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KB0 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KB0 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KB0 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
2050 2060 2070 2080 2090 2100
2090 2100 2110
pF1KB0 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
:::::::::::::::::::::::::::::::::
XP_011 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
2110 2120 2130
>>XP_011543357 (OMIM: 164009,612376) PREDICTED: nuclear (2133 aa)
initn: 13241 init1: 10798 opt: 10843 Z-score: 3755.6 bits: 708.6 E(85289): 1.9e-202
Smith-Waterman score: 13209; 99.2% identity (99.2% similar) in 2133 aa overlap (1-2115:1-2133)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSIT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITRH
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780
pF1KB0 ----------------SKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALMTIIPDLSPNNPLSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KB0 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KB0 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KB0 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KB0 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KB0 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
2050 2060 2070 2080 2090 2100
2090 2100 2110
pF1KB0 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
:::::::::::::::::::::::::::::::::
XP_011 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
2110 2120 2130
>>XP_011543362 (OMIM: 164009,612376) PREDICTED: nuclear (2133 aa)
initn: 13241 init1: 10798 opt: 10843 Z-score: 3755.6 bits: 708.6 E(85289): 1.9e-202
Smith-Waterman score: 13209; 99.2% identity (99.2% similar) in 2133 aa overlap (1-2115:1-2133)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSIT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITRH
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780
pF1KB0 ----------------SKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALMTIIPDLSPNNPLSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KB0 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KB0 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KB0 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KB0 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KB0 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
2050 2060 2070 2080 2090 2100
2090 2100 2110
pF1KB0 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
:::::::::::::::::::::::::::::::::
XP_011 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
2110 2120 2130
>>XP_011543359 (OMIM: 164009,612376) PREDICTED: nuclear (2133 aa)
initn: 13241 init1: 10798 opt: 10843 Z-score: 3755.6 bits: 708.6 E(85289): 1.9e-202
Smith-Waterman score: 13209; 99.2% identity (99.2% similar) in 2133 aa overlap (1-2115:1-2133)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSIT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITRH
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780
pF1KB0 ----------------SKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALMTIIPDLSPNNPLSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KB0 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KB0 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KB0 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KB0 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KB0 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
2050 2060 2070 2080 2090 2100
2090 2100 2110
pF1KB0 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
:::::::::::::::::::::::::::::::::
XP_011 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
2110 2120 2130
>>XP_011543365 (OMIM: 164009,612376) PREDICTED: nuclear (2133 aa)
initn: 13241 init1: 10798 opt: 10843 Z-score: 3755.6 bits: 708.6 E(85289): 1.9e-202
Smith-Waterman score: 13209; 99.2% identity (99.2% similar) in 2133 aa overlap (1-2115:1-2133)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSIT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITRH
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780
pF1KB0 ----------------SKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALMTIIPDLSPNNPLSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KB0 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KB0 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KB0 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KB0 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KB0 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
2050 2060 2070 2080 2090 2100
2090 2100 2110
pF1KB0 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
:::::::::::::::::::::::::::::::::
XP_011 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
2110 2120 2130
>>XP_011543364 (OMIM: 164009,612376) PREDICTED: nuclear (2133 aa)
initn: 13241 init1: 10798 opt: 10843 Z-score: 3755.6 bits: 708.6 E(85289): 1.9e-202
Smith-Waterman score: 13209; 99.2% identity (99.2% similar) in 2133 aa overlap (1-2115:1-2133)
10 20 30 40 50 60
pF1KB0 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB0 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB0 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB0 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB0 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB0 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB0 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB0 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB0 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB0 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB0 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB0 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB0 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KB0 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSIT--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITRH
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780
pF1KB0 ----------------SKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALMTIIPDLSPNNPLSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KB0 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAPLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAP
1810 1820 1830 1840 1850 1860
1850 1860 1870 1880 1890 1900
pF1KB0 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSF
1870 1880 1890 1900 1910 1920
1910 1920 1930 1940 1950 1960
pF1KB0 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQ
1930 1940 1950 1960 1970 1980
1970 1980 1990 2000 2010 2020
pF1KB0 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLRRASMQPIQIAEGTGITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEG
1990 2000 2010 2020 2030 2040
2030 2040 2050 2060 2070 2080
pF1KB0 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRS
2050 2060 2070 2080 2090 2100
2090 2100 2110
pF1KB0 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
:::::::::::::::::::::::::::::::::
XP_011 GTRRSPRIATTTASAATAAAIGATPRAKGKAKH
2110 2120 2130
2115 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 01:59:20 2016 done: Fri Nov 4 01:59:23 2016
Total Scan time: 20.710 Total Display time: 1.790
Function used was FASTA [36.3.4 Apr, 2011]