Result of FASTA (omim) for
pF1KA2034
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA2034, 2036 aa
1>>>pF1KA2034 2036 - 2036 aa - 2036 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.5265+/-0.00054; mu= -36.2920+/- 0.033
mean_var=754.7141+/-156.802, 0's: 0 Z-trim(119.6): 643 B-trim: 0 in 0/56
Lambda= 0.046686
statistics sampled from 33145 (33896) to 33145 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.397), width: 16
Scan time: 22.040
The best scores are: opt bits E(85289)
NP_001139281 (OMIM: 600652,608568,614369) myosin-1 (2036) 13009 893.8 0
NP_079005 (OMIM: 600652,608568,614369) myosin-14 i (1995) 8442 586.2 1.2e-165
XP_006723449 (OMIM: 600652,608568,614369) PREDICTE (2003) 8442 586.2 1.2e-165
XP_011525625 (OMIM: 600652,608568,614369) PREDICTE (2003) 8442 586.2 1.2e-165
NP_001070654 (OMIM: 600652,608568,614369) myosin-1 (2003) 8442 586.2 1.2e-165
XP_011525623 (OMIM: 600652,608568,614369) PREDICTE (2035) 8442 586.2 1.2e-165
XP_011525622 (OMIM: 600652,608568,614369) PREDICTE (2043) 8442 586.2 1.2e-165
NP_001242941 (OMIM: 160776) myosin-10 isoform 1 [H (2007) 6225 436.9 1.1e-120
XP_011522177 (OMIM: 160776) PREDICTED: myosin-10 i (2037) 6225 436.9 1.1e-120
NP_005955 (OMIM: 160776) myosin-10 isoform 2 [Homo (1976) 5391 380.7 8.6e-104
XP_016880171 (OMIM: 160776) PREDICTED: myosin-10 i (1976) 5391 380.7 8.6e-104
XP_016880170 (OMIM: 160776) PREDICTED: myosin-10 i (1976) 5391 380.7 8.6e-104
NP_001243024 (OMIM: 160776) myosin-10 isoform 3 [H (1985) 5391 380.7 8.7e-104
XP_016880169 (OMIM: 160776) PREDICTED: myosin-10 i (1985) 5391 380.7 8.7e-104
XP_016880166 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 5391 380.7 8.7e-104
XP_016880167 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 5391 380.7 8.7e-104
XP_016880168 (OMIM: 160776) PREDICTED: myosin-10 i (1986) 5391 380.7 8.7e-104
XP_011522182 (OMIM: 160776) PREDICTED: myosin-10 i (2006) 5391 380.7 8.7e-104
XP_011522181 (OMIM: 160776) PREDICTED: myosin-10 i (2015) 5391 380.7 8.8e-104
XP_011522180 (OMIM: 160776) PREDICTED: myosin-10 i (2016) 5391 380.7 8.8e-104
XP_016884295 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
XP_016884294 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
XP_016884292 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
XP_011528499 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
NP_002464 (OMIM: 153640,153650,155100,160775,60020 (1960) 5245 370.9 7.8e-101
XP_016884293 (OMIM: 153640,153650,155100,160775,60 (1960) 5245 370.9 7.8e-101
NP_002465 (OMIM: 132900,160745) myosin-11 isoform (1972) 5079 359.7 1.8e-97
NP_001035203 (OMIM: 132900,160745) myosin-11 isofo (1979) 5079 359.7 1.8e-97
NP_074035 (OMIM: 132900,160745) myosin-11 isoform (1938) 5062 358.5 4e-97
XP_016878739 (OMIM: 132900,160745) PREDICTED: myos (1945) 5062 358.5 4e-97
NP_001035202 (OMIM: 132900,160745) myosin-11 isofo (1945) 5062 358.5 4e-97
XP_011520804 (OMIM: 132900,160745) PREDICTED: myos (1929) 5056 358.1 5.2e-97
XP_016880164 (OMIM: 160730) PREDICTED: myosin-1 is (1939) 2529 187.9 9.1e-46
NP_005954 (OMIM: 160730) myosin-1 [Homo sapiens] (1939) 2529 187.9 9.1e-46
NP_001093582 (OMIM: 160740,605637) myosin-2 [Homo (1941) 2525 187.7 1.1e-45
NP_060004 (OMIM: 160740,605637) myosin-2 [Homo sap (1941) 2525 187.7 1.1e-45
XP_011522173 (OMIM: 160720,178110,193700,601680) P (1940) 2518 187.2 1.5e-45
NP_002461 (OMIM: 160720,178110,193700,601680) myos (1940) 2518 187.2 1.5e-45
XP_011522172 (OMIM: 160720,178110,193700,601680) P (1940) 2518 187.2 1.5e-45
NP_002463 (OMIM: 158300,160741,608837) myosin-8 [H (1937) 2511 186.7 2.1e-45
XP_016876829 (OMIM: 160500,160760,181430,192600,25 (1935) 2510 186.6 2.2e-45
NP_000248 (OMIM: 160500,160760,181430,192600,25516 (1935) 2510 186.6 2.2e-45
NP_060003 (OMIM: 160742) myosin-4 [Homo sapiens] (1939) 2490 185.3 5.6e-45
XP_016880165 (OMIM: 160742) PREDICTED: myosin-4 is (1939) 2490 185.3 5.6e-45
NP_002462 (OMIM: 160710,192600,613251,613252,61408 (1939) 2457 183.1 2.6e-44
XP_011527249 (OMIM: 609928) PREDICTED: myosin-7B i (1738) 2448 182.4 3.6e-44
XP_011527250 (OMIM: 609928) PREDICTED: myosin-7B i (1738) 2448 182.4 3.6e-44
XP_016883476 (OMIM: 609928) PREDICTED: myosin-7B i (1807) 2448 182.4 3.8e-44
NP_065935 (OMIM: 609928) myosin-7B [Homo sapiens] (1983) 2448 182.5 4.1e-44
XP_006723903 (OMIM: 609928) PREDICTED: myosin-7B i (1989) 2448 182.5 4.1e-44
>>NP_001139281 (OMIM: 600652,608568,614369) myosin-14 is (2036 aa)
initn: 13009 init1: 13009 opt: 13009 Z-score: 4757.2 bits: 893.8 E(85289): 0
Smith-Waterman score: 13009; 100.0% identity (100.0% similar) in 2036 aa overlap (1-2036:1-2036)
10 20 30 40 50 60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
1990 2000 2010 2020 2030
>>NP_079005 (OMIM: 600652,608568,614369) myosin-14 isofo (1995 aa)
initn: 9989 init1: 8441 opt: 8442 Z-score: 3094.9 bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12621; 98.0% identity (98.0% similar) in 2036 aa overlap (1-2036:1-1995)
10 20 30 40 50 60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_079 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP--------G
190 200 210 220 230
250 260 270 280 290 300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------
600 610 620 630 640
670 680 690 700 710 720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
:::::::::::::::::::::::::::::::::::::::
NP_079 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
650 660 670
730 740 750 760 770 780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
680 690 700 710 720 730
790 800 810 820 830 840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
740 750 760 770 780 790
850 860 870 880 890 900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
800 810 820 830 840 850
910 920 930 940 950 960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660 1670 1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
1580 1590 1600 1610 1620 1630
1690 1700 1710 1720 1730 1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
1640 1650 1660 1670 1680 1690
1750 1760 1770 1780 1790 1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
1700 1710 1720 1730 1740 1750
1810 1820 1830 1840 1850 1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
1760 1770 1780 1790 1800 1810
1870 1880 1890 1900 1910 1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
1820 1830 1840 1850 1860 1870
1930 1940 1950 1960 1970 1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
1880 1890 1900 1910 1920 1930
1990 2000 2010 2020 2030
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
1940 1950 1960 1970 1980 1990
>>XP_006723449 (OMIM: 600652,608568,614369) PREDICTED: m (2003 aa)
initn: 8441 init1: 8441 opt: 8442 Z-score: 3094.8 bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12690; 98.4% identity (98.4% similar) in 2036 aa overlap (1-2036:1-2003)
10 20 30 40 50 60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------
610 620 630 640
670 680 690 700 710 720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
:::::::::::::::::::::::::::::::::::::::
XP_006 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
650 660 670 680
730 740 750 760 770 780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
690 700 710 720 730 740
790 800 810 820 830 840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
750 760 770 780 790 800
850 860 870 880 890 900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
810 820 830 840 850 860
910 920 930 940 950 960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
1350 1360 1370 1380 1390 1400
1450 1460 1470 1480 1490 1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
1410 1420 1430 1440 1450 1460
1510 1520 1530 1540 1550 1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
1590 1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
1650 1660 1670 1680 1690 1700
1750 1760 1770 1780 1790 1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
1710 1720 1730 1740 1750 1760
1810 1820 1830 1840 1850 1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
1770 1780 1790 1800 1810 1820
1870 1880 1890 1900 1910 1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
1830 1840 1850 1860 1870 1880
1930 1940 1950 1960 1970 1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
1890 1900 1910 1920 1930 1940
1990 2000 2010 2020 2030
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
1950 1960 1970 1980 1990 2000
>>XP_011525625 (OMIM: 600652,608568,614369) PREDICTED: m (2003 aa)
initn: 8441 init1: 8441 opt: 8442 Z-score: 3094.8 bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12690; 98.4% identity (98.4% similar) in 2036 aa overlap (1-2036:1-2003)
10 20 30 40 50 60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------
610 620 630 640
670 680 690 700 710 720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
:::::::::::::::::::::::::::::::::::::::
XP_011 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
650 660 670 680
730 740 750 760 770 780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
690 700 710 720 730 740
790 800 810 820 830 840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
750 760 770 780 790 800
850 860 870 880 890 900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
810 820 830 840 850 860
910 920 930 940 950 960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
1350 1360 1370 1380 1390 1400
1450 1460 1470 1480 1490 1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
1410 1420 1430 1440 1450 1460
1510 1520 1530 1540 1550 1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
1590 1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
1650 1660 1670 1680 1690 1700
1750 1760 1770 1780 1790 1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
1710 1720 1730 1740 1750 1760
1810 1820 1830 1840 1850 1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
1770 1780 1790 1800 1810 1820
1870 1880 1890 1900 1910 1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
1830 1840 1850 1860 1870 1880
1930 1940 1950 1960 1970 1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
1890 1900 1910 1920 1930 1940
1990 2000 2010 2020 2030
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
1950 1960 1970 1980 1990 2000
>>NP_001070654 (OMIM: 600652,608568,614369) myosin-14 is (2003 aa)
initn: 8441 init1: 8441 opt: 8442 Z-score: 3094.8 bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12690; 98.4% identity (98.4% similar) in 2036 aa overlap (1-2036:1-2003)
10 20 30 40 50 60
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA2 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA2 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA2 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA2 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA2 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA2 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA2 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA2 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA2 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA2 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------
610 620 630 640
670 680 690 700 710 720
pF1KA2 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
:::::::::::::::::::::::::::::::::::::::
NP_001 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
650 660 670 680
730 740 750 760 770 780
pF1KA2 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
690 700 710 720 730 740
790 800 810 820 830 840
pF1KA2 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
750 760 770 780 790 800
850 860 870 880 890 900
pF1KA2 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
810 820 830 840 850 860
910 920 930 940 950 960
pF1KA2 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KA2 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KA2 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KA2 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KA2 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KA2 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KA2 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KA2 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KA2 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
1350 1360 1370 1380 1390 1400
1450 1460 1470 1480 1490 1500
pF1KA2 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
1410 1420 1430 1440 1450 1460
1510 1520 1530 1540 1550 1560
pF1KA2 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KA2 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KA2 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
1590 1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KA2 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
1650 1660 1670 1680 1690 1700
1750 1760 1770 1780 1790 1800
pF1KA2 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
1710 1720 1730 1740 1750 1760
1810 1820 1830 1840 1850 1860
pF1KA2 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
1770 1780 1790 1800 1810 1820
1870 1880 1890 1900 1910 1920
pF1KA2 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
1830 1840 1850 1860 1870 1880
1930 1940 1950 1960 1970 1980
pF1KA2 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
1890 1900 1910 1920 1930 1940
1990 2000 2010 2020 2030
pF1KA2 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
1950 1960 1970 1980 1990 2000
>>XP_011525623 (OMIM: 600652,608568,614369) PREDICTED: m (2035 aa)
initn: 9989 init1: 8441 opt: 8442 Z-score: 3094.7 bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12621; 98.0% identity (98.0% similar) in 2036 aa overlap (1-2036:41-2035)
10 20 30
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFT
::::::::::::::::::::::::::::::
XP_011 AMPGSKEPEANQRWSRSLRTPRPSEGDRQTMAAVTMSVPGRKAPPRPGPVPEAAQPFLFT
20 30 40 50 60 70
40 50 60 70 80 90
pF1KA2 PRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLR
80 90 100 110 120 130
100 110 120 130 140 150
pF1KA2 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ
140 150 160 170 180 190
160 170 180 190 200 210
pF1KA2 LPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKK
200 210 220 230 240 250
220 230 240 250 260 270
pF1KA2 VIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRF
::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_011 VIQYLAHVASSPKGRKEPGVP--------GELERQLLQANPILEAFGNAKTVKNDNSSRF
260 270 280 290 300
280 290 300 310 320 330
pF1KA2 GKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA2 PCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA2 ERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEA
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA2 LAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKL
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA2 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA2 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA2 AALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQ
:::::::::::::::::: :::::::::
XP_011 AALLHQSTDRLTAEIWKD---------------------------------VEGIVGLEQ
670 680
700 710 720 730 740 750
pF1KA2 VSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEP
690 700 710 720 730 740
760 770 780 790 800 810
pF1KA2 RLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQ
750 760 770 780 790 800
820 830 840 850 860 870
pF1KA2 ALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQ
810 820 830 840 850 860
880 890 900 910 920 930
pF1KA2 QSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSA
870 880 890 900 910 920
940 950 960 970 980 990
pF1KA2 REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG
930 940 950 960 970 980
1000 1010 1020 1030 1040 1050
pF1KA2 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED
990 1000 1010 1020 1030 1040
1060 1070 1080 1090 1100 1110
pF1KA2 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE
1050 1060 1070 1080 1090 1100
1120 1130 1140 1150 1160 1170
pF1KA2 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS
1110 1120 1130 1140 1150 1160
1180 1190 1200 1210 1220 1230
pF1KA2 LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKR
1170 1180 1190 1200 1210 1220
1240 1250 1260 1270 1280 1290
pF1KA2 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE
1230 1240 1250 1260 1270 1280
1300 1310 1320 1330 1340 1350
pF1KA2 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV
1290 1300 1310 1320 1330 1340
1360 1370 1380 1390 1400 1410
pF1KA2 SGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL
1350 1360 1370 1380 1390 1400
1420 1430 1440 1450 1460 1470
pF1KA2 EEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKT
1410 1420 1430 1440 1450 1460
1480 1490 1500 1510 1520 1530
pF1KA2 ETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERE
1470 1480 1490 1500 1510 1520
1540 1550 1560 1570 1580 1590
pF1KA2 RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER
1530 1540 1550 1560 1570 1580
1600 1610 1620 1630 1640 1650
pF1KA2 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR
1590 1600 1610 1620 1630 1640
1660 1670 1680 1690 1700 1710
pF1KA2 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA
1650 1660 1670 1680 1690 1700
1720 1730 1740 1750 1760 1770
pF1KA2 QMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDE
1710 1720 1730 1740 1750 1760
1780 1790 1800 1810 1820 1830
pF1KA2 MADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTE
1770 1780 1790 1800 1810 1820
1840 1850 1860 1870 1880 1890
pF1KA2 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ
1830 1840 1850 1860 1870 1880
1900 1910 1920 1930 1940 1950
pF1KA2 ETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE
1890 1900 1910 1920 1930 1940
1960 1970 1980 1990 2000 2010
pF1KA2 ASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVAS
1950 1960 1970 1980 1990 2000
2020 2030
pF1KA2 DEEAEEAQPGSGPSPEPEGSPPAHPQ
::::::::::::::::::::::::::
XP_011 DEEAEEAQPGSGPSPEPEGSPPAHPQ
2010 2020 2030
>>XP_011525622 (OMIM: 600652,608568,614369) PREDICTED: m (2043 aa)
initn: 8441 init1: 8441 opt: 8442 Z-score: 3094.7 bits: 586.2 E(85289): 1.2e-165
Smith-Waterman score: 12690; 98.4% identity (98.4% similar) in 2036 aa overlap (1-2036:41-2043)
10 20 30
pF1KA2 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFT
::::::::::::::::::::::::::::::
XP_011 AMPGSKEPEANQRWSRSLRTPRPSEGDRQTMAAVTMSVPGRKAPPRPGPVPEAAQPFLFT
20 30 40 50 60 70
40 50 60 70 80 90
pF1KA2 PRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLR
80 90 100 110 120 130
100 110 120 130 140 150
pF1KA2 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ
140 150 160 170 180 190
160 170 180 190 200 210
pF1KA2 LPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKK
200 210 220 230 240 250
220 230 240 250 260 270
pF1KA2 VIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KA2 GKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLE
320 330 340 350 360 370
340 350 360 370 380 390
pF1KA2 PCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKR
380 390 400 410 420 430
400 410 420 430 440 450
pF1KA2 ERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEA
440 450 460 470 480 490
460 470 480 490 500 510
pF1KA2 LAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKL
500 510 520 530 540 550
520 530 540 550 560 570
pF1KA2 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
560 570 580 590 600 610
580 590 600 610 620 630
pF1KA2 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV
620 630 640 650 660 670
640 650 660 670 680 690
pF1KA2 AALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQ
:::::::::::::::::: :::::::::
XP_011 AALLHQSTDRLTAEIWKD---------------------------------VEGIVGLEQ
680 690
700 710 720 730 740 750
pF1KA2 VSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEP
700 710 720 730 740 750
760 770 780 790 800 810
pF1KA2 RLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQ
760 770 780 790 800 810
820 830 840 850 860 870
pF1KA2 ALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQ
820 830 840 850 860 870
880 890 900 910 920 930
pF1KA2 QSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSA
880 890 900 910 920 930
940 950 960 970 980 990
pF1KA2 REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVG
940 950 960 970 980 990
1000 1010 1020 1030 1040 1050
pF1KA2 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED
1000 1010 1020 1030 1040 1050
1060 1070 1080 1090 1100 1110
pF1KA2 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE
1060 1070 1080 1090 1100 1110
1120 1130 1140 1150 1160 1170
pF1KA2 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKS
1120 1130 1140 1150 1160 1170
1180 1190 1200 1210 1220 1230
pF1KA2 LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKR
1180 1190 1200 1210 1220 1230
1240 1250 1260 1270 1280 1290
pF1KA2 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAE
1240 1250 1260 1270 1280 1290
1300 1310 1320 1330 1340 1350
pF1KA2 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENV
1300 1310 1320 1330 1340 1350
1360 1370 1380 1390 1400 1410
pF1KA2 SGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQL
1360 1370 1380 1390 1400 1410
1420 1430 1440 1450 1460 1470
pF1KA2 EEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKT
1420 1430 1440 1450 1460 1470
1480 1490 1500 1510 1520 1530
pF1KA2 ETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERE
1480 1490 1500 1510 1520 1530
1540 1550 1560 1570 1580 1590
pF1KA2 RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER
1540 1550 1560 1570 1580 1590
1600 1610 1620 1630 1640 1650
pF1KA2 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR
1600 1610 1620 1630 1640 1650
1660 1670 1680 1690 1700 1710
pF1KA2 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA
1660 1670 1680 1690 1700 1710
1720 1730 1740 1750 1760 1770
pF1KA2 QMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDE
1720 1730 1740 1750 1760 1770
1780 1790 1800 1810 1820 1830
pF1KA2 MADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTE
1780 1790 1800 1810 1820 1830
1840 1850 1860 1870 1880 1890
pF1KA2 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ
1840 1850 1860 1870 1880 1890
1900 1910 1920 1930 1940 1950
pF1KA2 ETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEE
1900 1910 1920 1930 1940 1950
1960 1970 1980 1990 2000 2010
pF1KA2 ASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVAS
1960 1970 1980 1990 2000 2010
2020 2030
pF1KA2 DEEAEEAQPGSGPSPEPEGSPPAHPQ
::::::::::::::::::::::::::
XP_011 DEEAEEAQPGSGPSPEPEGSPPAHPQ
2020 2030 2040
>>NP_001242941 (OMIM: 160776) myosin-10 isoform 1 [Homo (2007 aa)
initn: 8061 init1: 5325 opt: 6225 Z-score: 2287.8 bits: 436.9 E(85289): 1.1e-120
Smith-Waterman score: 8689; 66.4% identity (88.6% similar) in 1996 aa overlap (47-2032:27-2004)
20 30 40 50 60 70
pF1KA2 PGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEE
:..:::..:::.::: ::::::....: .
NP_001 MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGD
10 20 30 40 50
80 90 100 110 120 130
pF1KA2 EAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYT
:. :::::.:.. . .:.::.::::::::.::::::::::::::::::..:::::::::
NP_001 EVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYT
60 70 80 90 100 110
140 150 160 170 180 190
pF1KA2 YSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILC
:::::::::::::.::::.: :.::::::::::.:::.::..:.::: ::::::::::::
NP_001 YSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILC
120 130 140 150 160 170
200 210 220 230 240 250
pF1KA2 TGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA-SVSTVSY-GELERQLLQANPILE
::::::::::::::::::::::::: ::::. ..: : . :.. :::::::::::::::
NP_001 TGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPQESPKPVKHQGELERQLLQANPILE
180 190 200 210 220 230
260 270 280 290 300 310
pF1KA2 AFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQ
.:::::::::::::::::::::::::.::::::::::::::::::.:::::: .::::::
NP_001 SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ
240 250 260 270 280 290
320 330 340 350 360 370
pF1KA2 LLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELFQETLESLRVLGFSHEEIISM
::.::::.::.::::: ..::::.:: :::. .. ::::.:.....:::::::.::
NP_001 LLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSM
300 310 320 330 340 350
380 390 400 410 420 430
pF1KA2 LRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRD
:..::.:::::::..:.:::::::.::.::.:::::.:::..: .:.::.::::::::::
NP_001 LKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRD
360 370 380 390 400 410
440 450 460 470 480 490
pF1KA2 YVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIF
::::::::::::::.:::::::::::::::: :.:.::::. ::::::.:::::::::::
NP_001 YVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIF
420 430 440 450 460 470
500 510 520 530 540 550
pF1KA2 QLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPA
.:::::::::::::::::::::::::.::::::::::: :.:.:::::::::::::::::
NP_001 ELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPA
480 490 500 510 520 530
560 570 580 590 600 610
pF1KA2 NPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDY
::::.::::::::::::::::.::::..::::.: :::.::.:.:.::: ..::::::::
NP_001 NPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDY
540 550 560 570 580 590
620 630 640 650 660 670
pF1KA2 KANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERC
::.:::::::::::::::.:::::.::..::.:::: ..:. :: :
NP_001 KADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDEIQNIQRASFYDSV-----------
600 610 620 630 640
680 690 700 710 720 730
pF1KA2 SSAISPPGVEGIVGLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNP
:.. : :. ::::.::... . :. . ..::::::::::::::..::::: ::::
NP_001 -SGLHEPPVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNP
650 660 670 680 690 700
740 750 760 770 780 790
pF1KA2 SFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTP
.:::::.::::::::::.:.::::::::::::::::::::::::::.:::::::::::::
NP_001 NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP
710 720 730 740 750 760
800 810 820 830 840 850
pF1KA2 NAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSF
:::::::::::::::.::.::::::::::.:::::::::::::.::::::::.::::. :
NP_001 NAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFF
770 780 790 800 810 820
860 870 880 890 900 910
pF1KA2 QAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEV
::. ::::::.:: :.::: :::.:.:::::::::::::::::.:::::::::::::.:
NP_001 QAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE
830 840 850 860 870 880
920 930 940 950 960 970
pF1KA2 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL
:::. .:: ::.: : . :. :.. . :: ::. :::::.::.:: ::::: :.::
NP_001 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARL
890 900 910 920 930 940
980 990 1000 1010 1020 1030
pF1KA2 AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEK
::.::::: .. .::.:: :::: .. .:.:::..: :::.:: .:. ::::::::::::
NP_001 AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK
950 960 970 980 990 1000
1040 1050 1060 1070 1080 1090
pF1KA2 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE
::.:::.::.::..:::::::::. ::.::.:::.:: ::: ::::::.:.: :.: : :
NP_001 VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQE
1010 1020 1030 1040 1050 1060
1100 1110 1120 1130 1140 1150
pF1KA2 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ
. :.:.:.::.:::: :::::: ::.::::...::.:..: : . .::. ::..::::::
NP_001 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ
1070 1080 1090 1100 1110 1120
1160 1170 1180 1190 1200 1210
pF1KA2 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG
.::::..:: . . :: .:: :: .:: :::.:::...:.:::::.:::.::::::.
NP_001 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT
1130 1140 1150 1160 1170 1180
1220 1230 1240 1250 1260 1270
pF1KA2 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE
:::::::.: ::::::.::::::.::::.:::::. ::: .:..::::. :: ::.::::
NP_001 ELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE
1190 1200 1210 1220 1230 1240
1280 1290 1300 1310 1320 1330
pF1KA2 QARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGER
::.: :. ::.. .::.. .:: :.. :: .. :.:..:..:. :.::.......:.:
NP_001 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR
1250 1260 1270 1280 1290 1300
1340 1350 1360 1370 1380 1390
pF1KA2 ARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLA
:.: ::: .. : ::.::: :.:::.: :...:. .: :.::.:.::::::::: ::
NP_001 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN
1310 1320 1330 1340 1350 1360
1400 1410 1420 1430 1440 1450
pF1KA2 LGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEA
:.::.: .: : .:.:: ::: ::. ... . :.::.. ... ... :..:. :::
NP_001 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEA
1370 1380 1390 1400 1410 1420
1460 1470 1480 1490 1500 1510
pF1KA2 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF
... ..::::.::: ::. . :.::. . :::::::: :.::..:::..:.:::::.::
NP_001 KKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF
1430 1440 1450 1460 1470 1480
1520 1530 1540 1550 1560 1570
pF1KA2 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL
::::::::. : .:::.:::::.::.:..::::.::::: ::.::.::::. :::..
NP_001 DQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADM
1490 1500 1510 1520 1530 1540
1580 1590 1600 1610 1620 1630
pF1KA2 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK
: :.::::::::.:::::.. :. :: ....:.:. :::::: :.:::::::::..::.:
NP_001 EDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK
1550 1560 1570 1580 1590 1600
1640 1650 1660 1670 1680 1690
pF1KA2 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQM
.: ::::: ::: .::..: : ::.:. :.: ..:::::.::::..::.: .:..:.::.
NP_001 AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQI
1610 1620 1630 1640 1650 1660
1700 1710 1720 1730 1740 1750
pF1KA2 ASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ
.:.....:..:::::.:::::. ::.::.:.::.:::.:..::::.::.::::.:.::
NP_001 EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ
1670 1680 1690 1700 1710 1720
1760 1770 1780 1790 1800 1810
pF1KA2 EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSE
::::.:.::::.:.:.:::.:::..:. .:.:.:.:::.::.:..:::::::::::: :
NP_001 EELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNME
1730 1740 1750 1760 1770 1780
1820 1830 1840 1850 1860 1870
pF1KA2 LLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHK
:::::.:: :::..:..::.:::: . :....::::::: .::...: : ....... :
NP_001 LLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFK
1790 1800 1810 1820 1830 1840
1880 1890 1900 1910 1920 1930
pF1KA2 MTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLE
::.:::.:..: :::::::..:: ..:::::.::.:::. .:::.::: ::: ..:.:
NP_001 ATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQME
1850 1860 1870 1880 1890 1900
1940 1950 1960 1970 1980 1990
pF1KA2 KGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG-P
:.: :.::::::::::::::.::.:.::.:::::.:.::. :...:::.::.:::::: :
NP_001 KANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGP
1910 1920 1930 1940 1950 1960
2000 2010 2020 2030
pF1KA2 LTFTT-RTVRQVFRLEEGVA---SDEEAEEAQPGSGPSPEPEGSPPAHPQ
..:.. :. :. ..:: :.. ::...: : : : .::
NP_001 ISFSSSRSGRRQLHLE-GASLELSDDDTE-----SKTSDVNETQPPQSE
1970 1980 1990 2000
>>XP_011522177 (OMIM: 160776) PREDICTED: myosin-10 isofo (2037 aa)
initn: 8061 init1: 5325 opt: 6225 Z-score: 2287.7 bits: 436.9 E(85289): 1.1e-120
Smith-Waterman score: 8689; 66.4% identity (88.6% similar) in 1996 aa overlap (47-2032:57-2034)
20 30 40 50 60 70
pF1KA2 PGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEE
:..:::..:::.::: ::::::....: .
XP_011 VPFTMAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGD
30 40 50 60 70 80
80 90 100 110 120 130
pF1KA2 EAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYT
:. :::::.:.. . .:.::.::::::::.::::::::::::::::::..:::::::::
XP_011 EVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYT
90 100 110 120 130 140
140 150 160 170 180 190
pF1KA2 YSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILC
:::::::::::::.::::.: :.::::::::::.:::.::..:.::: ::::::::::::
XP_011 YSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILC
150 160 170 180 190 200
200 210 220 230 240 250
pF1KA2 TGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA-SVSTVSY-GELERQLLQANPILE
::::::::::::::::::::::::: ::::. ..: : . :.. :::::::::::::::
XP_011 TGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPQESPKPVKHQGELERQLLQANPILE
210 220 230 240 250 260
260 270 280 290 300 310
pF1KA2 AFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQ
.:::::::::::::::::::::::::.::::::::::::::::::.:::::: .::::::
XP_011 SFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQ
270 280 290 300 310 320
320 330 340 350 360 370
pF1KA2 LLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELFQETLESLRVLGFSHEEIISM
::.::::.::.::::: ..::::.:: :::. .. ::::.:.....:::::::.::
XP_011 LLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSM
330 340 350 360 370 380
380 390 400 410 420 430
pF1KA2 LRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRD
:..::.:::::::..:.:::::::.::.::.:::::.:::..: .:.::.::::::::::
XP_011 LKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRD
390 400 410 420 430 440
440 450 460 470 480 490
pF1KA2 YVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIF
::::::::::::::.:::::::::::::::: :.:.::::. ::::::.:::::::::::
XP_011 YVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIF
450 460 470 480 490 500
500 510 520 530 540 550
pF1KA2 QLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPA
.:::::::::::::::::::::::::.::::::::::: :.:.:::::::::::::::::
XP_011 ELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPA
510 520 530 540 550 560
560 570 580 590 600 610
pF1KA2 NPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDY
::::.::::::::::::::::.::::..::::.: :::.::.:.:.::: ..::::::::
XP_011 NPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDY
570 580 590 600 610 620
620 630 640 650 660 670
pF1KA2 KANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERC
::.:::::::::::::::.:::::.::..::.:::: ..:. :: :
XP_011 KADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDEIQNIQRASFYDSV-----------
630 640 650 660 670
680 690 700 710 720 730
pF1KA2 SSAISPPGVEGIVGLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNP
:.. : :. ::::.::... . :. . ..::::::::::::::..::::: ::::
XP_011 -SGLHEPPVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNP
680 690 700 710 720 730
740 750 760 770 780 790
pF1KA2 SFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTP
.:::::.::::::::::.:.::::::::::::::::::::::::::.:::::::::::::
XP_011 NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP
740 750 760 770 780 790
800 810 820 830 840 850
pF1KA2 NAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSF
:::::::::::::::.::.::::::::::.:::::::::::::.::::::::.::::. :
XP_011 NAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFF
800 810 820 830 840 850
860 870 880 890 900 910
pF1KA2 QAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEV
::. ::::::.:: :.::: :::.:.:::::::::::::::::.:::::::::::::.:
XP_011 QAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE
860 870 880 890 900 910
920 930 940 950 960 970
pF1KA2 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL
:::. .:: ::.: : . :. :.. . :: ::. :::::.::.:: ::::: :.::
XP_011 LQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARL
920 930 940 950 960 970
980 990 1000 1010 1020 1030
pF1KA2 AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEK
::.::::: .. .::.:: :::: .. .:.:::..: :::.:: .:. ::::::::::::
XP_011 AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEK
980 990 1000 1010 1020 1030
1040 1050 1060 1070 1080 1090
pF1KA2 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE
::.:::.::.::..:::::::::. ::.::.:::.:: ::: ::::::.:.: :.: : :
XP_011 VTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQE
1040 1050 1060 1070 1080 1090
1100 1110 1120 1130 1140 1150
pF1KA2 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ
. :.:.:.::.:::: :::::: ::.::::...::.:..: : . .::. ::..::::::
XP_011 VMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ
1100 1110 1120 1130 1140 1150
1160 1170 1180 1190 1200 1210
pF1KA2 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG
.::::..:: . . :: .:: :: .:: :::.:::...:.:::::.:::.::::::.
XP_011 GALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKT
1160 1170 1180 1190 1200 1210
1220 1230 1240 1250 1260 1270
pF1KA2 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE
:::::::.: ::::::.::::::.::::.:::::. ::: .:..::::. :: ::.::::
XP_011 ELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE
1220 1230 1240 1250 1260 1270
1280 1290 1300 1310 1320 1330
pF1KA2 QARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGER
::.: :. ::.. .::.. .:: :.. :: .. :.:..:..:. :.::.......:.:
XP_011 QAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR
1280 1290 1300 1310 1320 1330
1340 1350 1360 1370 1380 1390
pF1KA2 ARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLA
:.: ::: .. : ::.::: :.:::.: :...:. .: :.::.:.::::::::: ::
XP_011 LRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLN
1340 1350 1360 1370 1380 1390
1400 1410 1420 1430 1440 1450
pF1KA2 LGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEA
:.::.: .: : .:.:: ::: ::. ... . :.::.. ... ... :..:. :::
XP_011 LSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEA
1400 1410 1420 1430 1440 1450
1460 1470 1480 1490 1500 1510
pF1KA2 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF
... ..::::.::: ::. . :.::. . :::::::: :.::..:::..:.:::::.::
XP_011 KKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKF
1460 1470 1480 1490 1500 1510
1520 1530 1540 1550 1560 1570
pF1KA2 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL
::::::::. : .:::.:::::.::.:..::::.::::: ::.::.::::. :::..
XP_011 DQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADM
1520 1530 1540 1550 1560 1570
1580 1590 1600 1610 1620 1630
pF1KA2 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK
: :.::::::::.:::::.. :. :: ....:.:. :::::: :.:::::::::..::.:
XP_011 EDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK
1580 1590 1600 1610 1620 1630
1640 1650 1660 1670 1680 1690
pF1KA2 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQM
.: ::::: ::: .::..: : ::.:. :.: ..:::::.::::..::.: .:..:.::.
XP_011 AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQI
1640 1650 1660 1670 1680 1690
1700 1710 1720 1730 1740 1750
pF1KA2 ASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ
.:.....:..:::::.:::::. ::.::.:.::.:::.:..::::.::.::::.:.::
XP_011 EAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQ
1700 1710 1720 1730 1740 1750
1760 1770 1780 1790 1800 1810
pF1KA2 EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSE
::::.:.::::.:.:.:::.:::..:. .:.:.:.:::.::.:..:::::::::::: :
XP_011 EELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNME
1760 1770 1780 1790 1800 1810
1820 1830 1840 1850 1860 1870
pF1KA2 LLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHK
:::::.:: :::..:..::.:::: . :....::::::: .::...: : ....... :
XP_011 LLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFK
1820 1830 1840 1850 1860 1870
1880 1890 1900 1910 1920 1930
pF1KA2 MTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLE
::.:::.:..: :::::::..:: ..:::::.::.:::. .:::.::: ::: ..:.:
XP_011 ATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQME
1880 1890 1900 1910 1920 1930
1940 1950 1960 1970 1980 1990
pF1KA2 KGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG-P
:.: :.::::::::::::::.::.:.::.:::::.:.::. :...:::.::.:::::: :
XP_011 KANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGP
1940 1950 1960 1970 1980 1990
2000 2010 2020 2030
pF1KA2 LTFTT-RTVRQVFRLEEGVA---SDEEAEEAQPGSGPSPEPEGSPPAHPQ
..:.. :. :. ..:: :.. ::...: : : : .::
XP_011 ISFSSSRSGRRQLHLE-GASLELSDDDTE-----SKTSDVNETQPPQSE
2000 2010 2020 2030
>>NP_005955 (OMIM: 160776) myosin-10 isoform 2 [Homo sap (1976 aa)
initn: 8040 init1: 5325 opt: 5391 Z-score: 1984.3 bits: 380.7 E(85289): 8.6e-104
Smith-Waterman score: 8605; 66.0% identity (87.8% similar) in 1994 aa overlap (47-2032:27-1973)
20 30 40 50 60 70
pF1KA2 PGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEE
:..:::..:::.::: ::::::....: .
NP_005 MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGD
10 20 30 40 50
80 90 100 110 120 130
pF1KA2 EAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYT
:. :::::.:.. . .:.::.::::::::.::::::::::::::::::..:::::::::
NP_005 EVMVELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYT
60 70 80 90 100 110
140 150 160 170 180 190
pF1KA2 YSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILC
:::::::::::::.::::.: :.::::::::::.:::.::..:.::: ::::::::::::
NP_005 YSGLFCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILC
120 130 140 150 160 170
200 210 220 230 240 250
pF1KA2 TGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAF
::::::::::::::::::::::::: ::::. ..: :::::::::::::::.:
NP_005 TGESGAGKTENTKKVIQYLAHVASSHKGRKDHNIP--------GELERQLLQANPILESF
180 190 200 210 220
260 270 280 290 300 310
pF1KA2 GNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLL
::::::::::::::::::::::::.::::::::::::::::::.:::::: .::::::::
NP_005 GNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KA2 GGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELFQETLESLRVLGFSHEEIISMLR
.::::.::.::::: ..::::.:: :::. .. ::::.:.....:::::::.:::.
NP_005 SGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLK
290 300 310 320 330 340
380 390 400 410 420 430
pF1KA2 MVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYV
.::.:::::::..:.:::::::.::.::.:::::.:::..: .:.::.::::::::::::
NP_005 VVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYV
350 360 370 380 390 400
440 450 460 470 480 490
pF1KA2 QKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQL
::::::::::::.:::::::::::::::: :.:.::::. ::::::.:::::::::::.:
NP_005 QKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFEL
410 420 430 440 450 460
500 510 520 530 540 550
pF1KA2 NSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANP
::::::::::::::::::::::::.::::::::::: :.:.:::::::::::::::::::
NP_005 NSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANP
470 480 490 500 510 520
560 570 580 590 600 610
pF1KA2 PGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKA
::.::::::::::::::::.::::..::::.: :::.::.:.:.::: ..::::::::::
NP_005 PGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKA
530 540 550 560 570 580
620 630 640 650 660 670
pF1KA2 NEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSS
.:::::::::::::::.:::::.::..::.:::
NP_005 DEWLMKNMDPLNDNVATLLHQSSDRFVAELWKD---------------------------
590 600 610 620
680 690 700 710 720 730
pF1KA2 AISPPGVEGIVGLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNPSF
:. ::::.::... . :. . ..::::::::::::::..::::: ::::.:
NP_005 ------VDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNF
630 640 650 660 670
740 750 760 770 780 790
pF1KA2 VRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNA
::::.::::::::::.:.::::::::::::::::::::::::::.:::::::::::::::
NP_005 VRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNA
680 690 700 710 720 730
800 810 820 830 840 850
pF1KA2 IPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQA
:::::::::::::.::.::::::::::.:::::::::::::.::::::::.::::. :::
NP_005 IPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQA
740 750 760 770 780 790
860 870 880 890 900 910
pF1KA2 AARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQ
. ::::::.:: :.::: :::.:.:::::::::::::::::.:::::::::::::.: ::
NP_005 VCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQ
800 810 820 830 840 850
920 930 940 950 960 970
pF1KA2 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAA
:. .:: ::.: : . :. :.. . :: ::. :::::.::.:: ::::: :.::::
NP_005 AKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAA
860 870 880 890 900 910
980 990 1000 1010 1020 1030
pF1KA2 RKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVT
.::::: .. .::.:: :::: .. .:.:::..: :::.:: .:. ::::::::::::::
NP_005 KKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVT
920 930 940 950 960 970
1040 1050 1060 1070 1080 1090
pF1KA2 TEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEAT
.:::.::.::..:::::::::. ::.::.:::.:: ::: ::::::.:.: :.: : :.
NP_005 AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVM
980 990 1000 1010 1020 1030
1100 1110 1120 1130 1140 1150
pF1KA2 IADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAA
:.:.:.::.:::: :::::: ::.::::...::.:..: : . .::. ::..::::::.:
NP_005 ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA
1040 1050 1060 1070 1080 1090
1160 1170 1180 1190 1200 1210
pF1KA2 LARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGEL
:::..:: . . :: .:: :: .:: :::.:::...:.:::::.:::.::::::. ::
NP_005 LARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL
1100 1110 1120 1130 1140 1150
1220 1230 1240 1250 1260 1270
pF1KA2 EDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQA
:::::.: ::::::.::::::.::::.:::::. ::: .:..::::. :: ::.::::::
NP_005 EDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQA
1160 1170 1180 1190 1200 1210
1280 1290 1300 1310 1320 1330
pF1KA2 RRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERAR
.: :. ::.. .::.. .:: :.. :: .. :.:..:..:. :.::.......:.: :
NP_005 KRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLR
1220 1230 1240 1250 1260 1270
1340 1350 1360 1370 1380 1390
pF1KA2 AEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALG
.: ::: .. : ::.::: :.:::.: :...:. .: :.::.:.::::::::: :: :.
NP_005 VELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS
1280 1290 1300 1310 1320 1330
1400 1410 1420 1430 1440 1450
pF1KA2 SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARR
::.: .: : .:.:: ::: ::. ... . :.::.. ... ... :..:. :::..
NP_005 SRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKK
1340 1350 1360 1370 1380 1390
1460 1470 1480 1490 1500 1510
pF1KA2 RAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ
. ..::::.::: ::. . :.::. . :::::::: :.::..:::..:.:::::.::::
NP_005 KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ
1400 1410 1420 1430 1440 1450
1520 1530 1540 1550 1560 1570
pF1KA2 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA
::::::. : .:::.:::::.::.:..::::.::::: ::.::.::::. :::..:
NP_005 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED
1460 1470 1480 1490 1500 1510
1580 1590 1600 1610 1620 1630
pF1KA2 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ
:.::::::::.:::::.. :. :: ....:.:. :::::: :.:::::::::..::.:.:
NP_005 LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQ
1520 1530 1540 1550 1560 1570
1640 1650 1660 1670 1680 1690
pF1KA2 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS
::::: ::: .::..: : ::.:. :.: ..:::::.::::..::.: .:..:.::. .
NP_005 FERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEA
1580 1590 1600 1610 1620 1630
1700 1710 1720 1730 1740 1750
pF1KA2 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE
:.....:..:::::.:::::. ::.::.:.::.:::.:..::::.::.::::.:.::::
NP_005 ANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEE
1640 1650 1660 1670 1680 1690
1760 1770 1780 1790 1800 1810
pF1KA2 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL
::.:.::::.:.:.:::.:::..:. .:.:.:.:::.::.:..:::::::::::: :::
NP_005 LASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELL
1700 1710 1720 1730 1740 1750
1820 1830 1840 1850 1860 1870
pF1KA2 NDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMT
:::.:: :::..:..::.:::: . :....::::::: .::...: : ....... : :
NP_005 NDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKAT
1760 1770 1780 1790 1800 1810
1880 1890 1900 1910 1920 1930
pF1KA2 IAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKG
:.:::.:..: :::::::..:: ..:::::.::.:::. .:::.::: ::: ..:.::.
NP_005 ISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKA
1820 1830 1840 1850 1860 1870
1940 1950 1960 1970 1980 1990
pF1KA2 NLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRG-PLT
: :.::::::::::::::.::.:.::.:::::.:.::. :...:::.::.:::::: :..
NP_005 NARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPIS
1880 1890 1900 1910 1920 1930
2000 2010 2020 2030
pF1KA2 FTT-RTVRQVFRLEEGVA---SDEEAEEAQPGSGPSPEPEGSPPAHPQ
:.. :. :. ..:: :.. ::...: : : : .::
NP_005 FSSSRSGRRQLHLE-GASLELSDDDTE-----SKTSDVNETQPPQSE
1940 1950 1960 1970
2036 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:28:32 2016 done: Wed Nov 2 22:28:36 2016
Total Scan time: 22.040 Total Display time: 1.550
Function used was FASTA [36.3.4 Apr, 2011]