Result of FASTA (omim) for pF1KA2014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KA2014, 1027 aa
  1>>>pF1KA2014 1027 - 1027 aa - 1027 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.9722+/-0.000455; mu= -0.0307+/- 0.029
 mean_var=459.1704+/-92.926, 0's: 0 Z-trim(122.4): 89  B-trim: 151 in 1/61
 Lambda= 0.059853
 statistics sampled from 40407 (40503) to 40407 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.475), width:  16
 Scan time: 15.450

The best scores are:                                      opt bits E(85289)
NP_783863 (OMIM: 616288) formin-like protein 3 iso (1027) 6765 599.5 3.1e-170
XP_005269275 (OMIM: 616288) PREDICTED: formin-like (1028) 6559 581.7 6.9e-165
XP_011537271 (OMIM: 616288) PREDICTED: formin-like (1046) 6475 574.5 1.1e-162
XP_011537273 (OMIM: 616288) PREDICTED: formin-like (1000) 6271 556.8 2.1e-157
XP_011537270 (OMIM: 616288) PREDICTED: formin-like (1047) 6269 556.7 2.4e-157
XP_011537276 (OMIM: 616288) PREDICTED: formin-like (1003) 6263 556.1 3.4e-157
XP_011537272 (OMIM: 616288) PREDICTED: formin-like (1046) 6245 554.6  1e-156
XP_011537275 (OMIM: 616288) PREDICTED: formin-like ( 925) 5530 492.8 3.6e-138
NP_944489 (OMIM: 616288) formin-like protein 3 iso ( 976) 5401 481.7 8.4e-135
XP_011537274 (OMIM: 616288) PREDICTED: formin-like ( 996) 5195 463.9 1.9e-129
XP_011508836 (OMIM: 616285) PREDICTED: formin-like (1076) 2478 229.3 8.6e-59
XP_005246322 (OMIM: 616285) PREDICTED: formin-like (1084) 2478 229.3 8.6e-59
XP_005246320 (OMIM: 616285) PREDICTED: formin-like (1087) 2478 229.4 8.7e-59
XP_011508835 (OMIM: 616285) PREDICTED: formin-like (1091) 2478 229.4 8.7e-59
NP_443137 (OMIM: 616285) formin-like protein 2 [Ho (1092) 2478 229.4 8.7e-59
XP_011508834 (OMIM: 616285) PREDICTED: formin-like (1093) 2478 229.4 8.7e-59
XP_011508833 (OMIM: 616285) PREDICTED: formin-like (1094) 2478 229.4 8.7e-59
XP_011508832 (OMIM: 616285) PREDICTED: formin-like (1099) 2478 229.4 8.7e-59
XP_011508838 (OMIM: 616285) PREDICTED: formin-like ( 860) 2345 217.8 2.1e-55
XP_011508837 (OMIM: 616285) PREDICTED: formin-like (1048) 2345 217.8 2.4e-55
XP_006722133 (OMIM: 604656) PREDICTED: formin-like (1104) 1870 176.9 5.6e-43
XP_006722129 (OMIM: 604656) PREDICTED: formin-like (1110) 1870 176.9 5.6e-43
NP_005883 (OMIM: 604656) formin-like protein 1 [Ho (1100) 1838 174.1 3.8e-42
XP_011523484 (OMIM: 604656) PREDICTED: formin-like (1106) 1838 174.1 3.8e-42
XP_011523482 (OMIM: 604656) PREDICTED: formin-like (1133) 1830 173.4 6.2e-42
XP_006722128 (OMIM: 604656) PREDICTED: formin-like (1148) 1830 173.4 6.3e-42
XP_006722127 (OMIM: 604656) PREDICTED: formin-like (1154) 1830 173.4 6.3e-42
XP_006722126 (OMIM: 604656) PREDICTED: formin-like (1158) 1830 173.4 6.3e-42
XP_011523481 (OMIM: 604656) PREDICTED: formin-like (1164) 1830 173.4 6.3e-42
XP_006722125 (OMIM: 604656) PREDICTED: formin-like (1164) 1830 173.4 6.3e-42
XP_006722132 (OMIM: 604656) PREDICTED: formin-like (1076) 1547 149.0 1.4e-34
NP_056160 (OMIM: 606627) disheveled-associated act (1067)  977 99.7 8.9e-20
NP_001188356 (OMIM: 606627) disheveled-associated  (1068)  868 90.3 6.1e-17
XP_006715103 (OMIM: 606627) PREDICTED: disheveled- (1167)  868 90.4 6.4e-17
NP_001257449 (OMIM: 606626) disheveled-associated  (1068)  864 90.0 7.7e-17
XP_006715108 (OMIM: 606627) PREDICTED: disheveled- (1077)  862 89.8 8.7e-17
XP_006715109 (OMIM: 606627) PREDICTED: disheveled- (1077)  862 89.8 8.7e-17
XP_006715106 (OMIM: 606627) PREDICTED: disheveled- (1077)  862 89.8 8.7e-17
XP_006715105 (OMIM: 606627) PREDICTED: disheveled- (1077)  862 89.8 8.7e-17
XP_016866119 (OMIM: 606627) PREDICTED: disheveled- (1100)  862 89.8 8.8e-17
XP_006715102 (OMIM: 606627) PREDICTED: disheveled- (1176)  862 89.8 9.2e-17
XP_005267487 (OMIM: 606626) PREDICTED: disheveled- (1078)  835 87.5 4.4e-16
NP_055807 (OMIM: 606626) disheveled-associated act (1078)  835 87.5 4.4e-16
XP_005267488 (OMIM: 606626) PREDICTED: disheveled- (1078)  835 87.5 4.4e-16
NP_112194 (OMIM: 609129,614567) protein diaphanous ( 849)  681 74.1 3.8e-12
XP_006719939 (OMIM: 609129,614567) PREDICTED: prot ( 930)  681 74.1   4e-12
NP_001245298 (OMIM: 609129,614567) protein diaphan (1112)  681 74.2 4.5e-12
NP_001245297 (OMIM: 609129,614567) protein diaphan (1123)  681 74.2 4.5e-12
XP_011533560 (OMIM: 609129,614567) PREDICTED: prot (1136)  681 74.2 4.6e-12
NP_001245296 (OMIM: 609129,614567) protein diaphan (1147)  681 74.2 4.6e-12


>>NP_783863 (OMIM: 616288) formin-like protein 3 isoform  (1027 aa)
 initn: 6765 init1: 6765 opt: 6765  Z-score: 3177.4  bits: 599.5 E(85289): 3.1e-170
Smith-Waterman score: 6765; 100.0% identity (100.0% similar) in 1027 aa overlap (1-1027:1-1027)

               10        20        30        40        50        60
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA2 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA2 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA2 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA2 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA2 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA2 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA2 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA2 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA2 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA2 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA2 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA2 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA2 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA2 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA2 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA2 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
              970       980       990      1000      1010      1020

              
pF1KA2 PRAPGPH
       :::::::
NP_783 PRAPGPH
              

>>XP_005269275 (OMIM: 616288) PREDICTED: formin-like pro  (1028 aa)
 initn: 6682 init1: 6559 opt: 6559  Z-score: 3081.2  bits: 581.7 E(85289): 6.9e-165
Smith-Waterman score: 6559; 98.8% identity (99.4% similar) in 1014 aa overlap (1-1014:1-1014)

               10        20        30        40        50        60
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA2 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA2 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KA2 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KA2 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KA2 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KA2 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KA2 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KA2 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KA2 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KA2 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KA2 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KA2 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KA2 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KA2 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KA2 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KA2 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
       :::::::::::::::::::::::::::::::::::::: :.  :...:   :..      
XP_005 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDA
              970       980       990      1000      1010      1020

               
pF1KA2 PRAPGPH 
               
XP_005 AHHDESNC
               

>>XP_011537271 (OMIM: 616288) PREDICTED: formin-like pro  (1046 aa)
 initn: 6469 init1: 6469 opt: 6475  Z-score: 3041.9  bits: 574.5 E(85289): 1.1e-162
Smith-Waterman score: 6475; 98.1% identity (98.5% similar) in 1010 aa overlap (18-1027:45-1046)

                            10        20        30        40       
pF1KA2              MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNL
                                     : .: :. .:   :    .:     :::::
XP_011 LKEGPQCSKGKWCRWHLSARQLCEGPKGCGPYILWPSAFP---PASSGDR-----SSMNL
           20        30        40        50           60           

        50        60        70        80        90       100       
pF1KA2 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
         70        80        90       100       110       120      

       110       120       130       140       150       160       
pF1KA2 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
        130       140       150       160       170       180      

       170       180       190       200       210       220       
pF1KA2 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
        190       200       210       220       230       240      

       230       240       250       260       270       280       
pF1KA2 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
        250       260       270       280       290       300      

       290       300       310       320       330       340       
pF1KA2 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
        310       320       330       340       350       360      

       350       360       370       380       390       400       
pF1KA2 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
        370       380       390       400       410       420      

       410       420       430       440       450       460       
pF1KA2 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
        430       440       450       460       470       480      

       470       480       490       500       510       520       
pF1KA2 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
        490       500       510       520       530       540      

       530       540       550       560       570       580       
pF1KA2 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
        550       560       570       580       590       600      

       590       600       610       620       630       640       
pF1KA2 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
        610       620       630       640       650       660      

       650       660       670       680       690       700       
pF1KA2 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
        670       680       690       700       710       720      

       710       720       730       740       750       760       
pF1KA2 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
        730       740       750       760       770       780      

       770       780       790       800       810       820       
pF1KA2 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
        790       800       810       820       830       840      

       830       840       850       860       870       880       
pF1KA2 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
        850       860       870       880       890       900      

       890       900       910       920       930       940       
pF1KA2 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
        910       920       930       940       950       960      

       950       960       970       980       990      1000       
pF1KA2 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
        970       980       990      1000      1010      1020      

      1010      1020       
pF1KA2 RHQARSAAPPSGPPRAPGPH
       ::::::::::::::::::::
XP_011 RHQARSAAPPSGPPRAPGPH
       1030      1040      

>>XP_011537273 (OMIM: 616288) PREDICTED: formin-like pro  (1000 aa)
 initn: 6391 init1: 6268 opt: 6271  Z-score: 2947.0  bits: 556.8 E(85289): 2.1e-157
Smith-Waterman score: 6271; 98.1% identity (99.0% similar) in 983 aa overlap (34-1014:4-986)

            10        20        30          40        50        60 
pF1KA2 LESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERF--ALVLSSMNLPPDKARLLRQYDNE
                                     :. .:  : .::::::::::::::::::::
XP_011                            MFALKMKFCRAKTLSSMNLPPDKARLLRQYDNE
                                          10        20        30   

              70        80        90       100       110       120 
pF1KA2 KKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNH
            40        50        60        70        80        90   

             130       140       150       160       170       180 
pF1KA2 IGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPP
           100       110       120       130       140       150   

             190       200       210       220       230       240 
pF1KA2 SALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGF
           160       170       180       190       200       210   

             250       260       270       280       290       300 
pF1KA2 NLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELH
           220       230       240       250       260       270   

             310       320       330       340       350       360 
pF1KA2 RFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRH
           280       290       300       310       320       330   

             370       380       390       400       410       420 
pF1KA2 TESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMM
           340       350       360       370       380       390   

             430       440       450       460       470       480 
pF1KA2 RVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESV
           400       410       420       430       440       450   

             490       500       510       520       530       540 
pF1KA2 DSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAP
           460       470       480       490       500       510   

             550       560       570       580       590       600 
pF1KA2 PLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDL
           520       530       540       550       560       570   

             610       620       630       640       650       660 
pF1KA2 DLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEI
           580       590       600       610       620       630   

             670       680       690       700       710       720 
pF1KA2 CRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVE
           640       650       660       670       680       690   

             730       740       750       760       770       780 
pF1KA2 RLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSK
           700       710       720       730       740       750   

             790       800       810       820       830       840 
pF1KA2 RGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSL
           760       770       780       790       800       810   

             850       860       870       880       890       900 
pF1KA2 ENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRY
           820       830       840       850       860       870   

             910       920       930       940       950       960 
pF1KA2 FGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQ
           880       890       900       910       920       930   

             970       980       990      1000      1010      1020 
pF1KA2 RNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGPP
       ::::::::::::::::::::::::::::::::::::: :.  :...:   :..       
XP_011 RNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAA
           940       950       960       970       980       990   

              
pF1KA2 RAPGPH 
              
XP_011 HHDESNC
          1000

>>XP_011537270 (OMIM: 616288) PREDICTED: formin-like pro  (1047 aa)
 initn: 6386 init1: 6263 opt: 6269  Z-score: 2945.8  bits: 556.7 E(85289): 2.4e-157
Smith-Waterman score: 6269; 96.9% identity (97.9% similar) in 997 aa overlap (18-1014:45-1033)

                            10        20        30        40       
pF1KA2              MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNL
                                     : .: :. .:   :    .:     :::::
XP_011 LKEGPQCSKGKWCRWHLSARQLCEGPKGCGPYILWPSAFP---PASSGDR-----SSMNL
           20        30        40        50           60           

        50        60        70        80        90       100       
pF1KA2 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
         70        80        90       100       110       120      

       110       120       130       140       150       160       
pF1KA2 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
        130       140       150       160       170       180      

       170       180       190       200       210       220       
pF1KA2 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
        190       200       210       220       230       240      

       230       240       250       260       270       280       
pF1KA2 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
        250       260       270       280       290       300      

       290       300       310       320       330       340       
pF1KA2 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
        310       320       330       340       350       360      

       350       360       370       380       390       400       
pF1KA2 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
        370       380       390       400       410       420      

       410       420       430       440       450       460       
pF1KA2 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
        430       440       450       460       470       480      

       470       480       490       500       510       520       
pF1KA2 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
        490       500       510       520       530       540      

       530       540       550       560       570       580       
pF1KA2 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
        550       560       570       580       590       600      

       590       600       610       620       630       640       
pF1KA2 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
        610       620       630       640       650       660      

       650       660       670       680       690       700       
pF1KA2 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
        670       680       690       700       710       720      

       710       720       730       740       750       760       
pF1KA2 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
        730       740       750       760       770       780      

       770       780       790       800       810       820       
pF1KA2 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
        790       800       810       820       830       840      

       830       840       850       860       870       880       
pF1KA2 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
        850       860       870       880       890       900      

       890       900       910       920       930       940       
pF1KA2 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
        910       920       930       940       950       960      

       950       960       970       980       990      1000       
pF1KA2 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::: :.  :...
XP_011 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTA
        970       980       990      1000      1010      1020      

      1010      1020        
pF1KA2 RHQARSAAPPSGPPRAPGPH 
       :   :..              
XP_011 RTAKRGSRFFCDAAHHDESNC
       1030      1040       

>>XP_011537276 (OMIM: 616288) PREDICTED: formin-like pro  (1003 aa)
 initn: 6386 init1: 6263 opt: 6263  Z-score: 2943.2  bits: 556.1 E(85289): 3.4e-157
Smith-Waterman score: 6263; 98.8% identity (99.4% similar) in 972 aa overlap (43-1014:18-989)

             20        30        40        50        60        70  
pF1KA2 EPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDNEKKWDLICDQER
                                     ::::::::::::::::::::::::::::::
XP_011              MHTVHVPRDEDAKNWAESSMNLPPDKARLLRQYDNEKKWDLICDQER
                            10        20        30        40       

             80        90       100       110       120       130  
pF1KA2 FQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTNHIGWVREFLNDE
        50        60        70        80        90       100       

            140       150       160       170       180       190  
pF1KA2 NKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQPPSALSAPFTNSL
       110       120       130       140       150       160       

            200       210       220       230       240       250  
pF1KA2 ARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYGFNLVMSHPHAVN
       170       180       190       200       210       220       

            260       270       280       290       300       310  
pF1KA2 EIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKELHRFEKLMEYFRN
       230       240       250       260       270       280       

            320       330       340       350       360       370  
pF1KA2 EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSRHTESEKLQVQIQ
       290       300       310       320       330       340       

            380       390       400       410       420       430  
pF1KA2 AYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENMMRVAELEKQLLQ
       350       360       370       380       390       400       

            440       450       460       470       480       490  
pF1KA2 REKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESVDSEALARVGPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESVDSEALARVGPA
       410       420       430       440       450       460       

            500       510       520       530       540       550  
pF1KA2 ELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPAPPLPGAAPSVVL
       470       480       490       500       510       520       

            560       570       580       590       600       610  
pF1KA2 TVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILEDLDLDKFEELFKT
       530       540       550       560       570       580       

            620       630       640       650       660       670  
pF1KA2 KAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEEICRAIHTFDLQT
       590       600       610       620       630       640       

            680       690       700       710       720       730  
pF1KA2 LPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKVERLTQRMAGMAF
       650       660       670       680       690       700       

            740       750       760       770       780       790  
pF1KA2 LGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSSKRGAVYGFKLQS
       710       720       730       740       750       760       

            800       810       820       830       840       850  
pF1KA2 LDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVSLENVLLDVKELG
       770       780       790       800       810       820       

            860       870       880       890       900       910  
pF1KA2 RGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVRYFGESPKTTPPS
       830       840       850       860       870       880       

            920       930       940       950       960       970  
pF1KA2 VFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPSQRNKWQQQELIA
       890       900       910       920       930       940       

            980       990      1000      1010      1020        
pF1KA2 ELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGPPRAPGPH 
       :::::::::::::::::::::::::: :.  :...:   :..              
XP_011 ELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDAAHHDESNC
       950       960       970       980       990      1000   

>>XP_011537272 (OMIM: 616288) PREDICTED: formin-like pro  (1046 aa)
 initn: 6366 init1: 4158 opt: 6245  Z-score: 2934.6  bits: 554.6 E(85289): 1e-156
Smith-Waterman score: 6251; 96.8% identity (97.8% similar) in 997 aa overlap (18-1014:45-1032)

                            10        20        30        40       
pF1KA2              MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNL
                                     : .: :. .:   :    .:     :::::
XP_011 LKEGPQCSKGKWCRWHLSARQLCEGPKGCGPYILWPSAFP---PASSGDR-----SSMNL
           20        30        40        50           60           

        50        60        70        80        90       100       
pF1KA2 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
         70        80        90       100       110       120      

       110       120       130       140       150       160       
pF1KA2 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
        130       140       150       160       170       180      

       170       180       190       200       210       220       
pF1KA2 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
        190       200       210       220       230       240      

       230       240       250       260       270       280       
pF1KA2 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
        250       260       270       280       290       300      

       290       300       310       320       330       340       
pF1KA2 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
        310       320       330       340       350       360      

       350       360       370       380       390       400       
pF1KA2 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
       :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLGLEEFLQ-SRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
        370        380       390       400       410       420     

       410       420       430       440       450       460       
pF1KA2 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
         430       440       450       460       470       480     

       470       480       490       500       510       520       
pF1KA2 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
         490       500       510       520       530       540     

       530       540       550       560       570       580       
pF1KA2 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
         550       560       570       580       590       600     

       590       600       610       620       630       640       
pF1KA2 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
         610       620       630       640       650       660     

       650       660       670       680       690       700       
pF1KA2 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
         670       680       690       700       710       720     

       710       720       730       740       750       760       
pF1KA2 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
         730       740       750       760       770       780     

       770       780       790       800       810       820       
pF1KA2 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
         790       800       810       820       830       840     

       830       840       850       860       870       880       
pF1KA2 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
         850       860       870       880       890       900     

       890       900       910       920       930       940       
pF1KA2 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
         910       920       930       940       950       960     

       950       960       970       980       990      1000       
pF1KA2 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::: :.  :...
XP_011 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTA
         970       980       990      1000      1010      1020     

      1010      1020        
pF1KA2 RHQARSAAPPSGPPRAPGPH 
       :   :..              
XP_011 RTAKRGSRFFCDAAHHDESNC
        1030      1040      

>>XP_011537275 (OMIM: 616288) PREDICTED: formin-like pro  (925 aa)
 initn: 5650 init1: 5527 opt: 5530  Z-score: 2601.6  bits: 492.8 E(85289): 3.6e-138
Smith-Waterman score: 5530; 98.5% identity (99.3% similar) in 864 aa overlap (151-1014:48-911)

              130       140       150       160       170       180
pF1KA2 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
                                     .:::::::::::::::::::::::::::::
XP_011 DLHGGRGQEGGEGLFLRGVYPEVRMIREESLFDFEGLESGDDGAFDKLRSWSRSIEDLQP
        20        30        40        50        60        70       

              190       200       210       220       230       240
pF1KA2 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
        80        90       100       110       120       130       

              250       260       270       280       290       300
pF1KA2 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
       140       150       160       170       180       190       

              310       320       330       340       350       360
pF1KA2 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
       200       210       220       230       240       250       

              370       380       390       400       410       420
pF1KA2 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
       260       270       280       290       300       310       

              430       440       450       460       470       480
pF1KA2 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
       320       330       340       350       360       370       

              490       500       510       520       530       540
pF1KA2 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
       380       390       400       410       420       430       

              550       560       570       580       590       600
pF1KA2 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
       440       450       460       470       480       490       

              610       620       630       640       650       660
pF1KA2 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
       500       510       520       530       540       550       

              670       680       690       700       710       720
pF1KA2 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
       560       570       580       590       600       610       

              730       740       750       760       770       780
pF1KA2 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
       620       630       640       650       660       670       

              790       800       810       820       830       840
pF1KA2 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
       680       690       700       710       720       730       

              850       860       870       880       890       900
pF1KA2 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
       740       750       760       770       780       790       

              910       920       930       940       950       960
pF1KA2 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
       800       810       820       830       840       850       

              970       980       990      1000      1010      1020
pF1KA2 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
       :::::::::::::::::::::::::::::::::::::: :.  :...:   :..      
XP_011 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTARTAKRGSRFFCDA
       860       870       880       890       900       910       

               
pF1KA2 PRAPGPH 
               
XP_011 AHHDESNC
       920     

>>NP_944489 (OMIM: 616288) formin-like protein 3 isoform  (976 aa)
 initn: 5400 init1: 5400 opt: 5401  Z-score: 2541.1  bits: 481.7 E(85289): 8.4e-135
Smith-Waterman score: 6317; 95.0% identity (95.0% similar) in 1027 aa overlap (1-1027:1-976)

               10        20        30        40        50        60
pF1KA2 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKARLLRQYDN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KA2 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 EKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQESTKVLRELEISLRTN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KA2 HIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDKLRSWSRSIEDLQP
       :::::::::::::::::::::::::::::::                             
NP_944 HIGWVREFLNDENKGLDVLVDYLSFAQCSVM-----------------------------
              130       140       150                              

              190       200       210       220       230       240
pF1KA2 PSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
                             ::::::::::::::::::::::::::::::::::::::
NP_944 ----------------------YSTLPGRRALKNSRLVSQKDDVHVCILCLRAIMNYQYG
                                   160       170       180         

              250       260       270       280       290       300
pF1KA2 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 FNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILAAFDNFKEVCKEL
     190       200       210       220       230       240         

              310       320       330       340       350       360
pF1KA2 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 HRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEFTKLGLEEFLQKSR
     250       260       270       280       290       300         

              370       380       390       400       410       420
pF1KA2 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 HTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSHLTEKLLDLENENM
     310       320       330       340       350       360         

              430       440       450       460       470       480
pF1KA2 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 MRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLES
     370       380       390       400       410       420         

              490       500       510       520       530       540
pF1KA2 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 VDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCPPA
     430       440       450       460       470       480         

              550       560       570       580       590       600
pF1KA2 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 PPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGTVFSELDDEKILED
     490       500       510       520       530       540         

              610       620       630       640       650       660
pF1KA2 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 LDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNLAITLRKAGRSAEE
     550       560       570       580       590       600         

              670       680       690       700       710       720
pF1KA2 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 ICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEELAAEDRFMLLFSKV
     610       620       630       640       650       660         

              730       740       750       760       770       780
pF1KA2 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 ERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQMLEIILALGNYMNSS
     670       680       690       700       710       720         

              790       800       810       820       830       840
pF1KA2 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 KRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFWHELHFVEKAAAVS
     730       740       750       760       770       780         

              850       860       870       880       890       900
pF1KA2 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 LENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRDAKTAEEAYNAVVR
     790       800       810       820       830       840         

              910       920       930       940       950       960
pF1KA2 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 YFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQLAQEAKKLDAKTPS
     850       860       870       880       890       900         

              970       980       990      1000      1010      1020
pF1KA2 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_944 QRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVVRHQARSAAPPSGP
     910       920       930       940       950       960         

              
pF1KA2 PRAPGPH
       :::::::
NP_944 PRAPGPH
     970      

>>XP_011537274 (OMIM: 616288) PREDICTED: formin-like pro  (996 aa)
 initn: 6040 init1: 5191 opt: 5195  Z-score: 2444.8  bits: 463.9 E(85289): 1.9e-129
Smith-Waterman score: 5821; 91.8% identity (92.8% similar) in 997 aa overlap (18-1014:45-982)

                            10        20        30        40       
pF1KA2              MGNLESAEGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNL
                                     : .: :. .:   :    .:     :::::
XP_011 LKEGPQCSKGKWCRWHLSARQLCEGPKGCGPYILWPSAFP---PASSGDR-----SSMNL
           20        30        40        50           60           

        50        60        70        80        90       100       
pF1KA2 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDKARLLRQYDNEKKWDLICDQERFQVKNPPHTYIQKLQSFLDPSVTRKKFRRRVQEST
         70        80        90       100       110       120      

       110       120       130       140       150       160       
pF1KA2 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVMFDFEGLESGDDGAFDK
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_011 KVLRELEISLRTNHIGWVREFLNDENKGLDVLVDYLSFAQCSVM----------------
        130       140       150       160       170                

       170       180       190       200       210       220       
pF1KA2 LRSWSRSIEDLQPPSALSAPFTNSLARSARQSVLRYSTLPGRRALKNSRLVSQKDDVHVC
                                          :::::::::::::::::::::::::
XP_011 -----------------------------------YSTLPGRRALKNSRLVSQKDDVHVC
                                                 180       190     

       230       240       250       260       270       280       
pF1KA2 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILCLRAIMNYQYGFNLVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIIL
         200       210       220       230       240       250     

       290       300       310       320       330       340       
pF1KA2 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAFDNFKEVCKELHRFEKLMEYFRNEDSNIDFMVACMQFINIVVHSVEDMNFRVHLQYEF
         260       270       280       290       300       310     

       350       360       370       380       390       400       
pF1KA2 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLGLEEFLQKSRHTESEKLQVQIQAYLDNVFDVGGLLEDAETKNVALEKVEELEEHVSH
         320       330       340       350       360       370     

       410       420       430       440       450       460       
pF1KA2 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQR
         380       390       400       410       420       430     

       470       480       490       500       510       520       
pF1KA2 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLP
         440       450       460       470       480       490     

       530       540       550       560       570       580       
pF1KA2 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPPPPLPDKCPPAPPLPGAAPSVVLTVGLSAIRIKKPIKTKFRLPVFNWTALKPNQISGT
         500       510       520       530       540       550     

       590       600       610       620       630       640       
pF1KA2 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSELDDEKILEDLDLDKFEELFKTKAQGPALDLICSKNKTAQKAASKVTLLEANRAKNL
         560       570       580       590       600       610     

       650       660       670       680       690       700       
pF1KA2 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AITLRKAGRSAEEICRAIHTFDLQTLPVDFVECLMRFLPTEAEVKLLRQYERERQPLEEL
         620       630       640       650       660       670     

       710       720       730       740       750       760       
pF1KA2 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEDRFMLLFSKVERLTQRMAGMAFLGNFQDNLQMLTPQLNAIIAASASVKSSQKLKQML
         680       690       700       710       720       730     

       770       780       790       800       810       820       
pF1KA2 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKMTLLHFIALTVKEKYPDLANFW
         740       750       760       770       780       790     

       830       840       850       860       870       880       
pF1KA2 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELHFVEKAAAVSLENVLLDVKELGRGMELIRRECSIHDNSVLRNFLSTNEGKLDKLQRD
         800       810       820       830       840       850     

       890       900       910       920       930       940       
pF1KA2 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKTAEEAYNAVVRYFGESPKTTPPSVFFPVFVRFIRSYKEAEQENEARKKQEEVMREKQL
         860       870       880       890       900       910     

       950       960       970       980       990      1000       
pF1KA2 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITGLHCQPMVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::: :.  :...
XP_011 AQEAKKLDAKTPSQRNKWQQQELIAELRRRQAKEHRPVYEGKDGTIEDIITVLKSVPFTA
         920       930       940       950       960       970     

      1010      1020        
pF1KA2 RHQARSAAPPSGPPRAPGPH 
       :   :..              
XP_011 RTAKRGSRFFCDAAHHDESNC
         980       990      




1027 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 20:16:41 2016 done: Thu Nov  3 20:16:43 2016
 Total Scan time: 15.450 Total Display time:  0.490

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com