Result of FASTA (omim) for
pF1KA1902
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1902, 1093 aa
1>>>pF1KA1902 1093 - 1093 aa - 1093 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.5880+/-0.000543; mu= -8.1060+/- 0.035
mean_var=860.8212+/-176.544, 0's: 0 Z-trim(122.8): 164 B-trim: 0 in 0/61
Lambda= 0.043714
statistics sampled from 41311 (41478) to 41311 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.486), width: 16
Scan time: 19.180
The best scores are: opt bits E(85289)
NP_443137 (OMIM: 616285) formin-like protein 2 [Ho (1092) 7144 467.1 2.5e-130
XP_011508832 (OMIM: 616285) PREDICTED: formin-like (1099) 7116 465.4 8.4e-130
XP_005246320 (OMIM: 616285) PREDICTED: formin-like (1087) 6922 453.1 4e-126
XP_005246322 (OMIM: 616285) PREDICTED: formin-like (1084) 6919 452.9 4.6e-126
XP_011508834 (OMIM: 616285) PREDICTED: formin-like (1093) 6899 451.7 1.1e-125
XP_011508833 (OMIM: 616285) PREDICTED: formin-like (1094) 6894 451.4 1.4e-125
XP_011508835 (OMIM: 616285) PREDICTED: formin-like (1091) 6891 451.2 1.6e-125
XP_011508837 (OMIM: 616285) PREDICTED: formin-like (1048) 5795 382.0 9.8e-105
XP_011508838 (OMIM: 616285) PREDICTED: formin-like ( 860) 5518 364.4 1.6e-99
XP_011508836 (OMIM: 616285) PREDICTED: formin-like (1076) 5265 348.6 1.1e-94
XP_006722128 (OMIM: 604656) PREDICTED: formin-like (1148) 2767 191.1 3.2e-47
XP_006722127 (OMIM: 604656) PREDICTED: formin-like (1154) 2744 189.7 8.7e-47
XP_006722133 (OMIM: 604656) PREDICTED: formin-like (1104) 2486 173.4 6.7e-42
NP_783863 (OMIM: 616288) formin-like protein 3 iso (1027) 2478 172.8 9.1e-42
XP_005269275 (OMIM: 616288) PREDICTED: formin-like (1028) 2478 172.8 9.1e-42
XP_006722129 (OMIM: 604656) PREDICTED: formin-like (1110) 2470 172.4 1.3e-41
XP_011537275 (OMIM: 616288) PREDICTED: formin-like ( 925) 2404 168.1 2.2e-40
XP_011537274 (OMIM: 616288) PREDICTED: formin-like ( 996) 2404 168.1 2.3e-40
NP_944489 (OMIM: 616288) formin-like protein 3 iso ( 976) 2401 167.9 2.6e-40
NP_005883 (OMIM: 604656) formin-like protein 1 [Ho (1100) 2397 167.7 3.3e-40
XP_006722126 (OMIM: 604656) PREDICTED: formin-like (1158) 2382 166.8 6.5e-40
XP_011523484 (OMIM: 604656) PREDICTED: formin-like (1106) 2381 166.7 6.6e-40
XP_011537273 (OMIM: 616288) PREDICTED: formin-like (1000) 2376 166.4 7.7e-40
XP_011537276 (OMIM: 616288) PREDICTED: formin-like (1003) 2368 165.9 1.1e-39
XP_011537271 (OMIM: 616288) PREDICTED: formin-like (1046) 2368 165.9 1.1e-39
XP_011537270 (OMIM: 616288) PREDICTED: formin-like (1047) 2368 165.9 1.1e-39
XP_011523482 (OMIM: 604656) PREDICTED: formin-like (1133) 2366 165.8 1.3e-39
XP_006722125 (OMIM: 604656) PREDICTED: formin-like (1164) 2366 165.8 1.3e-39
XP_011523481 (OMIM: 604656) PREDICTED: formin-like (1164) 2366 165.8 1.3e-39
XP_011537272 (OMIM: 616288) PREDICTED: formin-like (1046) 2353 164.9 2.2e-39
XP_006722132 (OMIM: 604656) PREDICTED: formin-like (1076) 2052 146.0 1.1e-33
NP_006720 (OMIM: 300108,300511) protein diaphanous (1101) 925 74.9 2.9e-12
NP_009293 (OMIM: 300108,300511) protein diaphanous (1096) 917 74.4 4.1e-12
NP_056160 (OMIM: 606627) disheveled-associated act (1067) 890 72.7 1.3e-11
NP_001188356 (OMIM: 606627) disheveled-associated (1068) 883 72.2 1.8e-11
XP_006715103 (OMIM: 606627) PREDICTED: disheveled- (1167) 883 72.3 1.9e-11
XP_006715105 (OMIM: 606627) PREDICTED: disheveled- (1077) 797 66.8 7.6e-10
XP_006715106 (OMIM: 606627) PREDICTED: disheveled- (1077) 797 66.8 7.6e-10
XP_006715108 (OMIM: 606627) PREDICTED: disheveled- (1077) 797 66.8 7.6e-10
XP_006715109 (OMIM: 606627) PREDICTED: disheveled- (1077) 797 66.8 7.6e-10
XP_016866119 (OMIM: 606627) PREDICTED: disheveled- (1100) 797 66.8 7.7e-10
XP_006715102 (OMIM: 606627) PREDICTED: disheveled- (1176) 797 66.9 8.1e-10
XP_005267487 (OMIM: 606626) PREDICTED: disheveled- (1078) 769 65.1 2.6e-09
NP_055807 (OMIM: 606626) disheveled-associated act (1078) 769 65.1 2.6e-09
XP_005267488 (OMIM: 606626) PREDICTED: disheveled- (1078) 769 65.1 2.6e-09
XP_011535875 (OMIM: 124900,602121,616632) PREDICTE (1250) 762 64.7 3.9e-09
XP_011535874 (OMIM: 124900,602121,616632) PREDICTE (1260) 762 64.7 3.9e-09
NP_001073280 (OMIM: 124900,602121,616632) protein (1263) 762 64.7 3.9e-09
NP_005210 (OMIM: 124900,602121,616632) protein dia (1272) 762 64.7 3.9e-09
NP_001300936 (OMIM: 124900,602121,616632) protein (1250) 758 64.5 4.6e-09
>>NP_443137 (OMIM: 616285) formin-like protein 2 [Homo s (1092 aa)
initn: 4324 init1: 3824 opt: 7144 Z-score: 2460.9 bits: 467.1 E(85289): 2.5e-130
Smith-Waterman score: 7144; 99.8% identity (99.9% similar) in 1093 aa overlap (1-1093:1-1092)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
NP_443 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
550 560 570 580 590
610 620 630 640 650 660
pF1KA1 TSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 TSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVD
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 EFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 EFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKA
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA1 IHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 IHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLM
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA1 QKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 QKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGA
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA1 VYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 VYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA1 LLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 LLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA1 ENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 ENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSH
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA1 KSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 KSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFDD
1020 1030 1040 1050 1060 1070
1090
pF1KA1 QNLRSVNGAEITM
:::::::::::::
NP_443 QNLRSVNGAEITM
1080 1090
>>XP_011508832 (OMIM: 616285) PREDICTED: formin-like pro (1099 aa)
initn: 4324 init1: 3824 opt: 7116 Z-score: 2451.3 bits: 465.4 E(85289): 8.4e-130
Smith-Waterman score: 7116; 99.1% identity (99.3% similar) in 1100 aa overlap (1-1093:1-1099)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
XP_011 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
550 560 570 580 590
610 620 630 640 650
pF1KA1 TSSPTVVFNSGLA-------AVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
::::::::::::: .:::::::::::::::::::::::::::::::::::::::
XP_011 TSSPTVVFNSGLADGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA1 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA1 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA1 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
780 790 800 810 820 830
840 850 860 870 880 890
pF1KA1 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KA1 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KA1 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRS
1020 1030 1040 1050 1060 1070
1080 1090
pF1KA1 VRRRFDDQNLRSVNGAEITM
::::::::::::::::::::
XP_011 VRRRFDDQNLRSVNGAEITM
1080 1090
>>XP_005246320 (OMIM: 616285) PREDICTED: formin-like pro (1087 aa)
initn: 4324 init1: 3824 opt: 6922 Z-score: 2385.3 bits: 453.1 E(85289): 4e-126
Smith-Waterman score: 6922; 98.5% identity (99.1% similar) in 1075 aa overlap (1-1075:1-1074)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
XP_005 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
550 560 570 580 590
610 620 630 640 650 660
pF1KA1 TSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVD
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 EFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKA
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA1 IHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLM
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA1 QKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGA
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA1 VYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA1 LLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA1 ENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSH
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA1 KSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFDD
::::::::::::::::::::::::::::::::::::: :... . :. ::
XP_005 KSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITALKKNNITKFPNVHSRVRISSST
1020 1030 1040 1050 1060 1070
1090
pF1KA1 QNLRSVNGAEITM
XP_005 PVVEDTQS
1080
>>XP_005246322 (OMIM: 616285) PREDICTED: formin-like pro (1084 aa)
initn: 7668 init1: 3824 opt: 6919 Z-score: 2384.3 bits: 452.9 E(85289): 4.6e-126
Smith-Waterman score: 6919; 97.7% identity (98.6% similar) in 1085 aa overlap (1-1084:1-1084)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
XP_005 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
550 560 570 580 590
610 620 630 640 650 660
pF1KA1 TSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVD
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 EFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKA
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA1 IHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLM
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA1 QKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGA
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA1 VYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA1 LLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA1 ENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSH
960 970 980 990 1000 1010
1030 1040 1050 1060 1070
pF1KA1 KSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVR-RSVRRRFD
::::::::::::::::::::::::::::::::::::: :... . :. : ..
XP_005 KSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITALKKNNITKFPNVHSRILETNHT
1020 1030 1040 1050 1060 1070
1080 1090
pF1KA1 DQNLRSVNGAEITM
:. .:
XP_005 DEPMR
1080
>>XP_011508834 (OMIM: 616285) PREDICTED: formin-like pro (1093 aa)
initn: 7341 init1: 3824 opt: 6899 Z-score: 2377.4 bits: 451.7 E(85289): 1.1e-125
Smith-Waterman score: 6899; 98.1% identity (98.5% similar) in 1080 aa overlap (1-1073:1-1079)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
XP_011 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
550 560 570 580 590
610 620 630 640 650
pF1KA1 TSSPTVVFNSGLA-------AVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
::::::::::::: .:::::::::::::::::::::::::::::::::::::::
XP_011 TSSPTVVFNSGLADGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA1 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA1 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA1 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
780 790 800 810 820 830
840 850 860 870 880 890
pF1KA1 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KA1 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KA1 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRS
:::::::::::::::::::::::::::::::::::::::::::: :.. :. : : :
XP_011 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITVLKTVPFTARTAKRGS
1020 1030 1040 1050 1060 1070
1080 1090
pF1KA1 VRRRFDDQNLRSVNGAEITM
XP_011 RFFCEPVLTEEYHY
1080 1090
>>XP_011508833 (OMIM: 616285) PREDICTED: formin-like pro (1094 aa)
initn: 4324 init1: 3824 opt: 6894 Z-score: 2375.7 bits: 451.4 E(85289): 1.4e-125
Smith-Waterman score: 6894; 97.8% identity (98.4% similar) in 1082 aa overlap (1-1075:1-1081)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
XP_011 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
550 560 570 580 590
610 620 630 640 650
pF1KA1 TSSPTVVFNSGLA-------AVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
::::::::::::: .:::::::::::::::::::::::::::::::::::::::
XP_011 TSSPTVVFNSGLADGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA1 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA1 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA1 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
780 790 800 810 820 830
840 850 860 870 880 890
pF1KA1 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KA1 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KA1 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRS
:::::::::::::::::::::::::::::::::::::::::::: :... . :.
XP_011 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITALKKNNITKFPNVHSR
1020 1030 1040 1050 1060 1070
1080 1090
pF1KA1 VRRRFDDQNLRSVNGAEITM
::
XP_011 VRISSSTPVVEDTQS
1080 1090
>>XP_011508835 (OMIM: 616285) PREDICTED: formin-like pro (1091 aa)
initn: 7332 init1: 3824 opt: 6891 Z-score: 2374.7 bits: 451.2 E(85289): 1.6e-125
Smith-Waterman score: 6891; 97.0% identity (98.0% similar) in 1092 aa overlap (1-1084:1-1091)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
XP_011 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
550 560 570 580 590
610 620 630 640 650
pF1KA1 TSSPTVVFNSGLA-------AVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
::::::::::::: .:::::::::::::::::::::::::::::::::::::::
XP_011 TSSPTVVFNSGLADGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA1 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA1 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA1 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
780 790 800 810 820 830
840 850 860 870 880 890
pF1KA1 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA1 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KA1 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KA1 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVR-R
:::::::::::::::::::::::::::::::::::::::::::: :... . :. :
XP_011 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITALKKNNITKFPNVHSR
1020 1030 1040 1050 1060 1070
1080 1090
pF1KA1 SVRRRFDDQNLRSVNGAEITM
.. :. .:
XP_011 ILETNHTDEPMR
1080 1090
>>XP_011508837 (OMIM: 616285) PREDICTED: formin-like pro (1048 aa)
initn: 4242 init1: 3253 opt: 5795 Z-score: 2001.3 bits: 382.0 E(85289): 9.8e-105
Smith-Waterman score: 6670; 94.5% identity (94.6% similar) in 1100 aa overlap (1-1093:1-1048)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::
XP_011 WVREFLNEENKGLDVLVEYLSFAQYAVT--------------------------------
130 140
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
:::::::::::::::::::::::::::::::::::::::::
XP_011 -------------------YNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
150 160 170 180
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
190 200 210 220 230 240
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
250 260 270 280 290 300
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
310 320 330 340 350 360
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
370 380 390 400 410 420
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
430 440 450 460 470 480
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
XP_011 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
490 500 510 520 530 540
610 620 630 640 650
pF1KA1 TSSPTVVFNSGLA-------AVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
::::::::::::: .:::::::::::::::::::::::::::::::::::::::
XP_011 TSSPTVVFNSGLADGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
550 560 570 580 590 600
660 670 680 690 700 710
pF1KA1 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
610 620 630 640 650 660
720 730 740 750 760 770
pF1KA1 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
670 680 690 700 710 720
780 790 800 810 820 830
pF1KA1 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
730 740 750 760 770 780
840 850 860 870 880 890
pF1KA1 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
790 800 810 820 830 840
900 910 920 930 940 950
pF1KA1 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
850 860 870 880 890 900
960 970 980 990 1000 1010
pF1KA1 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
910 920 930 940 950 960
1020 1030 1040 1050 1060 1070
pF1KA1 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRS
970 980 990 1000 1010 1020
1080 1090
pF1KA1 VRRRFDDQNLRSVNGAEITM
::::::::::::::::::::
XP_011 VRRRFDDQNLRSVNGAEITM
1030 1040
>>XP_011508838 (OMIM: 616285) PREDICTED: formin-like pro (860 aa)
initn: 3253 init1: 3253 opt: 5518 Z-score: 1907.8 bits: 364.4 E(85289): 1.6e-99
Smith-Waterman score: 5518; 98.8% identity (99.1% similar) in 861 aa overlap (240-1093:1-860)
210 220 230 240 250 260
pF1KA1 KNSRLVSKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLEL
::::::::::::::::::::::::::::::
XP_011 MVMSHPHAVNEIALSLNNKNPRTKALVLEL
10 20 30
270 280 290 300 310 320
pF1KA1 LAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDNNIDFMVASMQFINIVVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDNNIDFMVASMQFINIVVH
40 50 60 70 80 90
330 340 350 360 370 380
pF1KA1 SVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKN
100 110 120 130 140 150
390 400 410 420 430 440
pF1KA1 AALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVH
160 170 180 190 200 210
450 460 470 480 490 500
pF1KA1 TLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVV
220 230 240 250 260 270
510 520 530 540 550 560
pF1KA1 AGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPP
280 290 300 310 320 330
570 580 590 600 610 620
pF1KA1 PPPPPLPGPASETVPAPPLAPPLPSAPPLPGTSSPTVVFNSGLA-------AVKIKKPIK
:::: :::::.::::::::::::::::::::::::::::::::: .::::::::
XP_011 PPPP-LPGPAAETVPAPPLAPPLPSAPPLPGTSSPTVVFNSGLADGPIKLFSVKIKKPIK
340 350 360 370 380
630 640 650 660 670 680
pF1KA1 TKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQ
390 400 410 420 430 440
690 700 710 720 730 740
pF1KA1 KIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLP
450 460 470 480 490 500
750 760 770 780 790 800
pF1KA1 TENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQ
510 520 530 540 550 560
810 820 830 840 850 860
pF1KA1 LHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQ
570 580 590 600 610 620
870 880 890 900 910 920
pF1KA1 TLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHD
630 640 650 660 670 680
930 940 950 960 970 980
pF1KA1 HNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAY
690 700 710 720 730 740
990 1000 1010 1020 1030 1040
pF1KA1 KQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSHKSKRQQQELIAELRRRQVKDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSHKSKRQQQELIAELRRRQVKDNR
750 760 770 780 790 800
1050 1060 1070 1080 1090
pF1KA1 HVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFDDQNLRSVNGAEITM
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVYEGKDGAIEDIITDLRNQPYRRADAVRRSVRRRFDDQNLRSVNGAEITM
810 820 830 840 850 860
>>XP_011508836 (OMIM: 616285) PREDICTED: formin-like pro (1076 aa)
initn: 6042 init1: 3824 opt: 5265 Z-score: 1820.5 bits: 348.6 E(85289): 1.1e-94
Smith-Waterman score: 6931; 97.0% identity (97.2% similar) in 1100 aa overlap (1-1093:1-1076)
10 20 30 40 50 60
pF1KA1 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPPLPGPASETVPAPPLAPPLPSAPPLPG
::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::::
XP_011 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPP-LPGPAAETVPAPPLAPPLPSAPPLPG
550 560 570 580 590
610 620 630 640 650
pF1KA1 TSSPTVVFNSGLA-------AVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
::::::::::::: .:::::::::::::::::::::::::::::::::::::::
XP_011 TSSPTVVFNSGLADGPIKLFSVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERI
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA1 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKT
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA1 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQF
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA1 SKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYM
:::::::::::::::::::::::::::: :::::::::
XP_011 SKIERLMQKMTIMAFIGNFAESIQMLTP-----------------------IILALGNYM
780 790 800 810
840 850 860 870 880 890
pF1KA1 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAA
820 830 840 850 860 870
900 910 920 930 940 950
pF1KA1 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFD
880 890 900 910 920 930
960 970 980 990 1000 1010
pF1KA1 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQ
940 950 960 970 980 990
1020 1030 1040 1050 1060 1070
pF1KA1 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITDLRNQPYRRADAVRRS
1000 1010 1020 1030 1040 1050
1080 1090
pF1KA1 VRRRFDDQNLRSVNGAEITM
::::::::::::::::::::
XP_011 VRRRFDDQNLRSVNGAEITM
1060 1070
1093 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 11:25:39 2016 done: Thu Nov 3 11:25:41 2016
Total Scan time: 19.180 Total Display time: 0.520
Function used was FASTA [36.3.4 Apr, 2011]