Result of FASTA (omim) for
pF1KA1880
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1880, 612 aa
1>>>pF1KA1880 612 - 612 aa - 612 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4613+/-0.00042; mu= 19.2057+/- 0.026
mean_var=95.4306+/-22.490, 0's: 0 Z-trim(112.0): 250 B-trim: 2014 in 2/48
Lambda= 0.131290
statistics sampled from 20346 (20713) to 20346 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.243), width: 16
Scan time: 7.900
The best scores are: opt bits E(85289)
NP_001092742 (OMIM: 611237) BTB/POZ domain-contain ( 612) 4097 787.1 0
XP_011512581 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 612) 4097 787.1 0
NP_443125 (OMIM: 611237) BTB/POZ domain-containing ( 612) 4097 787.1 0
NP_689946 (OMIM: 611237) BTB/POZ domain-containing ( 544) 3641 700.7 3.3e-201
XP_011512583 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 391) 2567 497.1 4.5e-140
XP_016865716 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 2563 496.4 7.6e-140
XP_011512584 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 2563 496.4 7.6e-140
XP_011512582 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 401) 2563 496.4 7.7e-140
NP_001165889 (OMIM: 611237) BTB/POZ domain-contain ( 582) 2146 417.6 6e-116
NP_060267 (OMIM: 608531) BTB/POZ domain-containing ( 525) 353 77.9 9.6e-14
NP_001011885 (OMIM: 608530) BTB/POZ domain-contain ( 385) 345 76.3 2.2e-13
NP_079514 (OMIM: 608530) BTB/POZ domain-containing ( 482) 345 76.4 2.6e-13
NP_001269480 (OMIM: 615566) BTB/POZ domain-contain ( 461) 321 71.8 5.9e-12
NP_001269479 (OMIM: 615566) BTB/POZ domain-contain ( 461) 321 71.8 5.9e-12
XP_016883217 (OMIM: 615566) PREDICTED: BTB/POZ dom ( 461) 321 71.8 5.9e-12
XP_016883218 (OMIM: 615566) PREDICTED: BTB/POZ dom ( 461) 321 71.8 5.9e-12
NP_055777 (OMIM: 615566) BTB/POZ domain-containing ( 522) 321 71.8 6.4e-12
NP_852108 (OMIM: 615566) BTB/POZ domain-containing ( 565) 321 71.9 6.8e-12
NP_001244123 (OMIM: 605775,614495) kelch-like prot ( 555) 312 70.2 2.2e-11
NP_059111 (OMIM: 605775,614495) kelch-like protein ( 587) 312 70.2 2.3e-11
XP_011511576 (OMIM: 614214) PREDICTED: kelch-like ( 327) 299 67.5 8.2e-11
XP_016863164 (OMIM: 605774) PREDICTED: kelch-like ( 415) 298 67.4 1.1e-10
NP_569713 (OMIM: 614214) kelch-like protein 6 [Hom ( 621) 299 67.8 1.3e-10
XP_016863163 (OMIM: 605774) PREDICTED: kelch-like ( 555) 298 67.5 1.4e-10
NP_009177 (OMIM: 605774) kelch-like protein 2 isof ( 593) 298 67.5 1.4e-10
NP_001154993 (OMIM: 605774) kelch-like protein 2 i ( 597) 298 67.5 1.4e-10
XP_011529874 (OMIM: 605774) PREDICTED: kelch-like ( 633) 298 67.6 1.5e-10
XP_005247613 (OMIM: 611295) PREDICTED: kelch-like ( 600) 296 67.2 1.9e-10
XP_011511240 (OMIM: 611295) PREDICTED: kelch-like ( 600) 296 67.2 1.9e-10
XP_016862149 (OMIM: 611295) PREDICTED: kelch-like ( 600) 296 67.2 1.9e-10
XP_005247609 (OMIM: 611295) PREDICTED: kelch-like ( 600) 296 67.2 1.9e-10
NP_060114 (OMIM: 611295) kelch-like protein 24 [Ho ( 600) 296 67.2 1.9e-10
XP_016862148 (OMIM: 611295) PREDICTED: kelch-like ( 600) 296 67.2 1.9e-10
XP_005247612 (OMIM: 611295) PREDICTED: kelch-like ( 600) 296 67.2 1.9e-10
XP_005247611 (OMIM: 611295) PREDICTED: kelch-like ( 600) 296 67.2 1.9e-10
XP_005247610 (OMIM: 611295) PREDICTED: kelch-like ( 600) 296 67.2 1.9e-10
XP_016862146 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
XP_016862139 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
XP_016862147 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
XP_016862145 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
XP_016862144 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
XP_016862140 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
XP_016862141 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
XP_016862143 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
XP_016862142 (OMIM: 611295) PREDICTED: kelch-like ( 625) 296 67.2 1.9e-10
NP_001290038 (OMIM: 614522) kelch-like protein 12 ( 467) 291 66.1 3e-10
XP_016857484 (OMIM: 614522) PREDICTED: kelch-like ( 471) 291 66.1 3.1e-10
XP_011508139 (OMIM: 614522) PREDICTED: kelch-like ( 522) 291 66.2 3.3e-10
XP_011508138 (OMIM: 614522) PREDICTED: kelch-like ( 526) 291 66.2 3.3e-10
NP_067646 (OMIM: 614522) kelch-like protein 12 iso ( 568) 291 66.2 3.5e-10
>>NP_001092742 (OMIM: 611237) BTB/POZ domain-containing (612 aa)
initn: 4097 init1: 4097 opt: 4097 Z-score: 4199.4 bits: 787.1 E(85289): 0
Smith-Waterman score: 4097; 100.0% identity (100.0% similar) in 612 aa overlap (1-612:1-612)
10 20 30 40 50 60
pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP
550 560 570 580 590 600
610
pF1KA1 GSNSRSPNRQHQ
::::::::::::
NP_001 GSNSRSPNRQHQ
610
>>XP_011512581 (OMIM: 611237) PREDICTED: BTB/POZ domain- (612 aa)
initn: 4097 init1: 4097 opt: 4097 Z-score: 4199.4 bits: 787.1 E(85289): 0
Smith-Waterman score: 4097; 100.0% identity (100.0% similar) in 612 aa overlap (1-612:1-612)
10 20 30 40 50 60
pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP
550 560 570 580 590 600
610
pF1KA1 GSNSRSPNRQHQ
::::::::::::
XP_011 GSNSRSPNRQHQ
610
>>NP_443125 (OMIM: 611237) BTB/POZ domain-containing pro (612 aa)
initn: 4097 init1: 4097 opt: 4097 Z-score: 4199.4 bits: 787.1 E(85289): 0
Smith-Waterman score: 4097; 100.0% identity (100.0% similar) in 612 aa overlap (1-612:1-612)
10 20 30 40 50 60
pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 IVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 IGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 THNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSP
550 560 570 580 590 600
610
pF1KA1 GSNSRSPNRQHQ
::::::::::::
NP_443 GSNSRSPNRQHQ
610
>>NP_689946 (OMIM: 611237) BTB/POZ domain-containing pro (544 aa)
initn: 3641 init1: 3641 opt: 3641 Z-score: 3733.3 bits: 700.7 E(85289): 3.3e-201
Smith-Waterman score: 3641; 100.0% identity (100.0% similar) in 544 aa overlap (69-612:1-544)
40 50 60 70 80 90
pF1KA1 TFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTG
::::::::::::::::::::::::::::::
NP_689 MRESQPEAEIPLQDTTAEAFTMLLKYIYTG
10 20 30
100 110 120 130 140 150
pF1KA1 RATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 RATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLT
40 50 60 70 80 90
160 170 180 190 200 210
pF1KA1 CMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 CMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KA1 AEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 AEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIA
160 170 180 190 200 210
280 290 300 310 320 330
pF1KA1 TMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRIL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KA1 LWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNK
280 290 300 310 320 330
400 410 420 430 440 450
pF1KA1 IFHIVAFECMFTNKTFTLEKGLIVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 IFHIVAFECMFTNKTFTLEKGLIVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWD
340 350 360 370 380 390
460 470 480 490 500 510
pF1KA1 SGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKV
400 410 420 430 440 450
520 530 540 550 560 570
pF1KA1 SCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSL
460 470 480 490 500 510
580 590 600 610
pF1KA1 AGQQLDSHALRAPSGSSLPSSPGSNSRSPNRQHQ
::::::::::::::::::::::::::::::::::
NP_689 AGQQLDSHALRAPSGSSLPSSPGSNSRSPNRQHQ
520 530 540
>>XP_011512583 (OMIM: 611237) PREDICTED: BTB/POZ domain- (391 aa)
initn: 2567 init1: 2567 opt: 2567 Z-score: 2635.7 bits: 497.1 E(85289): 4.5e-140
Smith-Waterman score: 2567; 99.7% identity (100.0% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
:::::::::::::::::::::::::.
XP_011 VRVIDHSQYLCRSWQKLYFPARVCRFNWSYP
370 380 390
>>XP_016865716 (OMIM: 611237) PREDICTED: BTB/POZ domain- (387 aa)
initn: 2563 init1: 2563 opt: 2563 Z-score: 2631.7 bits: 496.4 E(85289): 7.6e-140
Smith-Waterman score: 2563; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
:::::::::::::::::::::::::
XP_016 VRVIDHSQYLCRSWQKLYFPARVCRKS
370 380
>>XP_011512584 (OMIM: 611237) PREDICTED: BTB/POZ domain- (387 aa)
initn: 2563 init1: 2563 opt: 2563 Z-score: 2631.7 bits: 496.4 E(85289): 7.6e-140
Smith-Waterman score: 2563; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
:::::::::::::::::::::::::
XP_011 VRVIDHSQYLCRSWQKLYFPARVCRKS
370 380
>>XP_011512582 (OMIM: 611237) PREDICTED: BTB/POZ domain- (401 aa)
initn: 2563 init1: 2563 opt: 2563 Z-score: 2631.5 bits: 496.4 E(85289): 7.7e-140
Smith-Waterman score: 2563; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 VRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGL
:::::::::::::::::::::::::
XP_011 VRVIDHSQYLCRSWQKLYFPARVCRSLFWCTATLPTLVYET
370 380 390 400
>>NP_001165889 (OMIM: 611237) BTB/POZ domain-containing (582 aa)
initn: 2251 init1: 2146 opt: 2146 Z-score: 2202.6 bits: 417.6 E(85289): 6e-116
Smith-Waterman score: 3619; 95.0% identity (95.0% similar) in 580 aa overlap (62-612:3-582)
40 50 60 70 80 90
pF1KA1 GEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTML
::::::::::::::::::::::::::::::
NP_001 MCRALLYGGMRESQPEAEIPLQDTTAEAFTML
10 20 30
100 110 120 130 140 150
pF1KA1 LKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KA1 YSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCK
100 110 120 130 140 150
220 230 240 250 260 270
pF1KA1 HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGML
160 170 180 190 200 210
280 290 300 310 320 330
pF1KA1 IPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSI
220 230 240 250 260 270
340 350 360 370 380
pF1KA1 INHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVC-------
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVCSGDGVSL
280 290 300 310 320 330
390 400 410 420
pF1KA1 ----------------------RYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIV
::::::::::::::::::::::::::::::::::::::
NP_001 WCPLWSRTPELKQSSLLGLPKCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIV
340 350 360 370 380 390
430 440 450 460 470 480
pF1KA1 PMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIG
400 410 420 430 440 450
490 500 510 520 530 540
pF1KA1 SIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTH
460 470 480 490 500 510
550 560 570 580 590 600
pF1KA1 NTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGS
520 530 540 550 560 570
610
pF1KA1 NSRSPNRQHQ
::::::::::
NP_001 NSRSPNRQHQ
580
>>NP_060267 (OMIM: 608531) BTB/POZ domain-containing pro (525 aa)
initn: 209 init1: 96 opt: 353 Z-score: 367.7 bits: 77.9 E(85289): 9.6e-14
Smith-Waterman score: 353; 29.6% identity (60.0% similar) in 240 aa overlap (22-245:103-337)
10 20 30 40
pF1KA1 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEK----KRF
..:... :. .: :: :.: : .:.
NP_060 GAERAEEAAGPGAAALQREAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRI
80 90 100 110 120 130
50 60 70 80 90 100
pF1KA1 PAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKE
:::: .::. : :.. ::: .. : :.: :. :: :::..:. .. . :
NP_060 PAHRFVLAVGSAVFDAMFNGGMATTSTEIELP--DVEPAAFLALLKFLYSDEVQIGPE--
140 150 160 170 180
110 120 130 140 150 160
pF1KA1 EVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDR
... : :.::. : :: :.: : .:. : . : :.. :.:. .: .:.
NP_060 -TVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDK
190 200 210 220 230 240
170 180 190 200 210
pF1KA1 NAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNW----CKHN----SKENHA
:. .....::: ... .:. .. ::... : .: :.. : :... . ::.
NP_060 NTADAITAEGFTDIDLDTLVAVLERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRR
250 260 270 280 290 300
220 230 240 250 260 270
pF1KA1 EIMQA----VRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEE
... .:.:::.. :. ::.:
NP_060 KVLGKALGLIRFPLMTIEEFAAGPAQSGILVDREVVSLFLHFTVNPKPRVEFIDRPRCCL
310 320 330 340 350 360
612 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 22:13:04 2016 done: Wed Nov 2 22:13:06 2016
Total Scan time: 7.900 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]