Result of FASTA (ccds) for
pF1KA1693
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1693, 867 aa
1>>>pF1KA1693 867 - 867 aa - 867 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3168+/-0.0011; mu= 2.9083+/- 0.066
mean_var=210.1515+/-43.023, 0's: 0 Z-trim(110.0): 48 B-trim: 100 in 2/50
Lambda= 0.088472
statistics sampled from 11289 (11321) to 11289 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.348), width: 16
Scan time: 4.950
The best scores are: opt bits E(32554)
CCDS72881.1 NBPF12 gene_id:149013|Hs108|chr1 (1457) 4495 587.3 6.5e-167
CCDS41381.2 NBPF11 gene_id:200030|Hs108|chr1 ( 865) 4487 586.2 8.5e-167
CCDS76206.1 NBPF10 gene_id:100132406|Hs108|chr1 (3795) 4461 583.2 2.9e-165
CCDS72895.1 NBPF9 gene_id:400818|Hs108|chr1 ( 942) 4422 577.9 2.9e-164
CCDS72896.1 NBPF9 gene_id:400818|Hs108|chr1 (1111) 4422 577.9 3.3e-164
CCDS72852.1 NBPF15 gene_id:284565|Hs108|chr1 ( 670) 2855 377.8 3.5e-104
CCDS216.1 NBPF3 gene_id:84224|Hs108|chr1 ( 633) 2654 352.1 1.8e-96
CCDS81275.1 NBPF3 gene_id:84224|Hs108|chr1 ( 577) 2575 342.0 1.8e-93
CCDS57977.1 NBPF3 gene_id:84224|Hs108|chr1 ( 563) 2283 304.8 2.9e-82
CCDS72856.1 NBPF20 gene_id:100288142|Hs108|chr1 (5207) 1891 255.3 2.1e-66
CCDS57976.1 NBPF3 gene_id:84224|Hs108|chr1 ( 621) 1549 211.1 5e-54
CCDS44184.1 NBPF6 gene_id:653149|Hs108|chr1 ( 638) 1146 159.7 1.6e-38
CCDS44182.1 NBPF4 gene_id:148545|Hs108|chr1 ( 638) 1146 159.7 1.6e-38
>>CCDS72881.1 NBPF12 gene_id:149013|Hs108|chr1 (1457 aa)
initn: 8981 init1: 4491 opt: 4495 Z-score: 3110.1 bits: 587.3 E(32554): 6.5e-167
Smith-Waterman score: 4966; 86.5% identity (89.4% similar) in 898 aa overlap (1-823:272-1169)
10 20 30
pF1KA1 MVVSAGPLSSEKAEMNILEINEKLHPQLAE
::::::::::::::::::::::::.:::::
CCDS72 VDRKSSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAE
250 260 270 280 290 300
40 50 60 70 80 90
pF1KA1 KKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAE
::::::.::::::::::: :::.::::::::::::::::::::: :::::::::::::::
CCDS72 KKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAE
310 320 330 340 350 360
100 110 120 130 140 150
pF1KA1 ELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAE
::::::::::::::::::::::::::::::::::.:::::::::.:::::::::::::::
CCDS72 ELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAE
370 380 390 400 410 420
160 170 180 190 200 210
pF1KA1 GCRLAQQLFQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAIT
::::::.: ::::::::::::::::::: :::::::.:::.:::::::::::::::::::
CCDS72 GCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSSPREMQKAEESKVPEDSLEECAIT
430 440 450 460 470 480
220 230 240 250 260 270
pF1KA1 CSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNV
:::::::::::::::::.::::::::::.:::::::::::::::.:::::::::::::::
CCDS72 CSNSHGPCDSNQPHKNIKITFEEDKVNSSLVVDRESSHDECQDALNILPVPGPTSSATNV
490 500 510 520 530 540
280 290 300 310 320 330
pF1KA1 SMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYK
:::::::::::::::::::::::::.:::::::::::.:::::::::.:::::.::::::
CCDS72 SMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYK
550 560 570 580 590 600
340 350 360 370 380 390
pF1KA1 YEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA
:::::::.::::::: ::::::::::::::::::::::::::::::::::::::::::::
CCDS72 YEECKDLLKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA
610 620 630 640 650 660
400 410 420 430 440 450
pF1KA1 SRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVA
:::::.:::::::::.:::::::::::::::::::.::::::::::::::::::::::::
CCDS72 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVA
670 680 690 700 710 720
460 470 480 490 500 510
pF1KA1 EKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDST
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 EKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDST
730 740 750 760 770 780
520 530 540 550 560 570
pF1KA1 LTGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSI
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSI
790 800 810 820 830 840
580 590 600 610 620
pF1KA1 PPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK---
::: :::::::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS72 PPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLAEKEPE
850 860 870 880 890 900
pF1KA1 -----------------G------------------------------------------
:
CCDS72 VLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPS
910 920 930 940 950 960
630 640 650 660 670
pF1KA1 -------------PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD
:::::::::::::::::::::::::::: ::::::::::::::::::
CCDS72 CPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD
970 980 990 1000 1010 1020
680 690 700 710 720 730
pF1KA1 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
CCDS72 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYRSSF
1030 1040 1050 1060 1070 1080
740 750 760 770 780 790
pF1KA1 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEV
:::::::::::::::::::::::::::::::::.:::::::::::::::::::. :.
CCDS72 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLSRELLAE
1090 1100 1110 1120 1130 1140
800 810 820 830 840 850
pF1KA1 EEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSL
.:::::::::: :::::.:. : : :
CCDS72 KEPEVLQDSLDRWYSTPSVYLGLTDPCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED
1150 1160 1170 1180 1190 1200
>--
initn: 1694 init1: 1694 opt: 1694 Z-score: 1178.0 bits: 229.8 E(32554): 2.7e-59
Smith-Waterman score: 1694; 88.2% identity (93.4% similar) in 287 aa overlap (581-867:1171-1457)
560 570 580 590 600 610
pF1KA1 SEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKE
: :.:. ::.:.: .:::. . . : .:
CCDS72 EKEPEVLQDSLDRWYSTPSVYLGLTDPCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE
1150 1160 1170 1180 1190 1200
620 630 640 650 660 670
pF1KA1 DQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL
::. . :::::::: :: :::::::::::::::::::::::::::: :::::::::::::
CCDS72 DQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGL
1210 1220 1230 1240 1250 1260
680 690 700 710 720 730
pF1KA1 ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP
1270 1280 1290 1300 1310 1320
740 750 760 770 780 790
pF1KA1 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNG
: ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::.
CCDS72 YRSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLNS
1330 1340 1350 1360 1370 1380
800 810 820 830 840 850
pF1KA1 VLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTL
:::::::::::::::: ::::::::::::::::::::::::::::::.::: .:: ::::
CCDS72 VLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHITFALDMDNSFFTL
1390 1400 1410 1420 1430 1440
860
pF1KA1 TVTSLHLVFQMEVIFPQ
::::::::::: :::::
CCDS72 TVTSLHLVFQMGVIFPQ
1450
>--
initn: 1642 init1: 1642 opt: 1642 Z-score: 1142.1 bits: 223.2 E(32554): 2.7e-57
Smith-Waterman score: 1642; 93.0% identity (97.8% similar) in 271 aa overlap (1-271:1-271)
10 20 30 40 50 60
pF1KA1 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKY
::::::: ::::::::::::::::.:::::.:::::::::.::.:::: ::::.:.::::
CCDS72 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNLKERCFLTQLAGFLANRQKKYKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAE
::::.:::::::::.::::::::::::::::::::::: ::::::::::::::::::: :
CCDS72 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLVQKLSPENDEDEDEDVQVEEDE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL
:::::::::::::::::::::::::::::::::::::::: ::::::.::::::::::..
CCDS72 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA
::::.:::::::::.::::::::::::::::
CCDS72 VVDRKSSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA
CCDS72 EKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQA
310 320 330 340 350 360
>>CCDS41381.2 NBPF11 gene_id:200030|Hs108|chr1 (865 aa)
initn: 6034 init1: 4483 opt: 4487 Z-score: 3108.0 bits: 586.2 E(32554): 8.5e-167
Smith-Waterman score: 4607; 85.6% identity (90.9% similar) in 838 aa overlap (1-832:1-819)
10 20 30 40 50 60
pF1KA1 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKY
::::::: ::::::::::::::::.:::::.:::::::::.::.:::: ::::.:.::::
CCDS41 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNLKERCFLTQLAGFLANRQKKYKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAE
::::.:::::::::.:::::::::::::::::::::.: ::::::::::::::::::: :
CCDS41 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL
:::::::::::::::::::::::::::::::::::::::: ::::::.::::::::::.:
CCDS41 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA
::::::::: ::::.:::::::::::::::::::::::::::::::::::::::: ::::
CCDS41 VVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA
:::::::.:::::::::.:::::.::::::::::::::::::::::::::::::::::::
CCDS41 EKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLA
:::::::::::::::::::::::::::::::::::.:::::::::.::::::::::::::
CCDS41 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
:::::.:::::::::::::::::::::::::::::::.::::::::::::::::::::::
CCDS41 EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSHVEWEDAVHIIPENESDDEEEEEK
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
CCDS41 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
CCDS41 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV
::::::::::::::::::::::::::: :::::::::::::::: :: : : ::: ::
CCDS41 RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
: ::.: .:::.:.:.:.: :: :::: : ::::::::: :::::::::::::::::.
CCDS41 YVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED
:: :: ::: :. :.:::...:..::: .:.: .: :::
CCDS41 YLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEED
730 740 750 760
790 800 810 820 830
pF1KA1 QNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFEL-PDS-----FQHYRSVFYSFEE
:.::::::. :.:: :::::::::: : . : : : :.:.:. . .:
CCDS41 QGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPVVLNSLTPASPTEVPFMHWRKNMLAFLL
770 780 790 800 810 820
840 850 860
pF1KA1 QHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
CCDS41 TWEKLKRRGRGRKEGEEDQRRKEEGEEKKGKKIKTHHAPGSAAC
830 840 850 860
>>CCDS76206.1 NBPF10 gene_id:100132406|Hs108|chr1 (3795 aa)
initn: 17763 init1: 4457 opt: 4461 Z-score: 3080.5 bits: 583.2 E(32554): 2.9e-165
Smith-Waterman score: 4956; 86.4% identity (89.3% similar) in 898 aa overlap (1-823:1-898)
10 20 30 40 50 60
pF1KA1 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKY
::::::: :::::::::::::: :.:::::::::::.::::::.:::: ::::.:.::::
CCDS76 MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAE
::: .:::::::::.:::::::::::::::::::::.: :::::::::::::::::::::
CCDS76 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL
:::::::::::::::::::::::::::::::::::::::::::::::.::::::.:::.:
CCDS76 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA
::::::::::::::.::::::::::::::::::::::::::::::::::::::::.::::
CCDS76 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA
::::::::::::::.:::. ::::::.:::::::::::: ::::::::::::::::::::
CCDS76 EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLA
:::::::::::.::::::::.::::::::::::::.:::::::: .::::::::::::::
CCDS76 EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSHVEWEDAVHIIPENESDDEEEEEK
: ::::: ::::::::::::::::::::::: ::::::::::::::::::::::::::::
CCDS76 TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
550 560 570 580 590 600
610 620 630
pF1KA1 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDS-------------------------
:::::::::::::::::::::::::::::::::::
CCDS76 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAF
610 620 630 640 650 660
640
pF1KA1 --------------------------------------------------LDRCYSTPSG
::::::::::
CCDS76 YILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG
670 680 690 700 710 720
650 660 670 680 690 700
pF1KA1 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
730 740 750 760 770 780
710 720 730 740 750 760
pF1KA1 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
790 800 810 820 830 840
770 780 790 800 810 820
pF1KA1 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY
:::::::::::::::::::::::. :.. . ::::::::: :::::: .:: :: :
CCDS76 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY
850 860 870 880 890 900
830 840 850 860
pF1KA1 RSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
CCDS76 RSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS
910 920 930 940 950 960
>--
initn: 14767 init1: 1495 opt: 1587 Z-score: 1098.0 bits: 216.4 E(32554): 7.7e-55
Smith-Waterman score: 1640; 43.5% identity (64.3% similar) in 767 aa overlap (147-844:2112-2871)
120 130 140 150 160 170
pF1KA1 RDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPEN---DEDEDED
.:...:. .. : : .. : ::
CCDS76 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEI
2090 2100 2110 2120 2130 2140
180 190 200 210 220 230
pF1KA1 VQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINIT
. .:.:. . : :: :. .: .: .:::..: : :. : .::... .
CCDS76 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS
2150 2160 2170 2180 2190 2200
240 250 260 270 280
pF1KA1 FEEDKVNSALVVDR-ESSHDECQDAVNILPVPGPTSSATNV--SMVVSAGPLSSEKAEMN
.::. .. :: ::: .....: .: : : . .: :.. . .. .
CCDS76 LEEQYLGLALDVDRIKKDQEEEEDQGP--PCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
2210 2220 2230 2240 2250
290 300 310 320 330 340
pF1KA1 ILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQ
:: .. .: ..: :.:: .: ....: : .. . : :....
CCDS76 CLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
2260 2270 2280 2290 2300 2310
350 360 370 380 390
pF1KA1 FKEEKLAEQLKQAEELRQYK---VLVHSQERELT------QLREKLREGRDASRSLNQHL
.:.. . ..:: . : :: : .: . .: .. . :.: :.:.
CCDS76 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ-
2320 2330 2340 2350 2360 2370
400 410 420 430 440
pF1KA1 QALLTPDKPDKSQGQDLQEQLAEGC-RLTQHLVQKLSPE--NDNDD--------------
.. :. : . . :...:. .: ::...:... :: .:. :
CCDS76 HVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD
2380 2390 2400 2410 2420 2430
450 460 470
pF1KA1 ---------------------DEDVQVEVAEKVQKSSAP-----REMQKAEEKEVPEDSL
: : . :. . .. : ::. .. : :: .:::
CCDS76 LGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSL
2440 2450 2460 2470 2480 2490
480 490 500 510 520 530
pF1KA1 EECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSSHVEWEDAVHIIPENE
..: : :. :: ::. .. ..:: .: .: .: .... . . . . : .
CCDS76 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR
2500 2510 2520 2530 2540 2550
540 550 560 570 580
pF1KA1 SDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQSYSSTFHS
.: ::...: :: .: .:. : :.: :. ::: : :. : : : :.:.
CCDS76 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV
2560 2570 2580 2590 2600 2610
590 600 610 620 630 640
pF1KA1 LEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYL
::.:.: .:::. . . : .:::. . ::::::::::: :::::::::::::::::::
CCDS76 LEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL
2620 2630 2640 2650 2660 2670
650 660 670 680 690 700
pF1KA1 ELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 ELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL
2680 2690 2700 2710 2720 2730
710 720 730 740 750 760
pF1KA1 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK
2740 2750 2760 2770 2780 2790
770 780 790 800 810 820
pF1KA1 KERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRS
:::::::::::::::::::::. :.. . ::::::::: :::::: .:: :: : :::
CCDS76 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS
2800 2810 2820 2830 2840 2850
830 840 850 860
pF1KA1 VFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
.:: .:.::...:. .:
CCDS76 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP
2860 2870 2880 2890 2900 2910
>--
initn: 5812 init1: 1495 opt: 1587 Z-score: 1098.0 bits: 216.4 E(32554): 7.7e-55
Smith-Waterman score: 1643; 43.8% identity (64.8% similar) in 768 aa overlap (147-844:1136-1895)
120 130 140 150 160 170
pF1KA1 RDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLF-----QKLSPENDEDED
.:...:. .. : :... : ::
CCDS76 RLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEI
1110 1120 1130 1140 1150 1160
180 190 200 210 220
pF1KA1 EDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIN
: : :.:. . : :: :. .: .: .:::..: : :. : .::...
CCDS76 EKYQ--EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV
1170 1180 1190 1200 1210 1220
230 240 250 260 270 280
pF1KA1 ITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNV--SMVVSAGPLSSEKAEM
..::. .. :: ::: ..:: .. . : : . .: :.. . ..
CCDS76 YSLEEQYLGLALDVDR-IKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS
1230 1240 1250 1260 1270 1280
290 300 310 320 330 340
pF1KA1 NILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNER
. :: .. .: ..: :.:: .: ....: : .. . : :...
CCDS76 SCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK
1290 1300 1310 1320 1330
350 360 370 380 390
pF1KA1 QFKEEKLAEQLKQAEELRQYK---VLVHSQERELT------QLREKLREGRDASRSLNQH
. .:.. . ..:: . : :: : .: . .: .. . :.: :.:.
CCDS76 EGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ
1340 1350 1360 1370 1380 1390
400 410 420 430 440
pF1KA1 LQALLTPDKPDKSQGQDLQEQLAEGC-RLTQHLVQKLSPE--NDNDD-------------
.. .. : . . :...:. .: ::...:... :: .:. :
CCDS76 -RVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP
1400 1410 1420 1430 1440 1450
450 460 470
pF1KA1 -------------DE-------DV-QVEVAEKVQKSSAP------REMQKAEEKEVPEDS
.: :: ... :. .... : ::. .. : :: .::
CCDS76 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDS
1460 1470 1480 1490 1500 1510
480 490 500 510 520 530
pF1KA1 LEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSSHVEWEDAVHIIPEN
:..: : :. :: ::. .. ..:: .: .: .: .... . . . . :
CCDS76 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER
1520 1530 1540 1550 1560 1570
540 550 560 570 580
pF1KA1 ESDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQSYSSTFH
. .: ::...: :: .: .:. : :.: :. ::: : :. : : : :.:.
CCDS76 RRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY
1580 1590 1600 1610 1620 1630
590 600 610 620 630 640
pF1KA1 SLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGY
::.:.: .:::. . . : .:::. . ::::::::::: ::::::::::::::::::
CCDS76 VLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY
1640 1650 1660 1670 1680 1690
650 660 670 680 690 700
pF1KA1 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEV
1700 1710 1720 1730 1740 1750
710 720 730 740 750 760
pF1KA1 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
1760 1770 1780 1790 1800 1810
770 780 790 800 810 820
pF1KA1 KKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYR
::::::::::::::::::::::. :.. . ::::::::: :::::: .:: :: : ::
CCDS76 KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYR
1820 1830 1840 1850 1860 1870
830 840 850 860
pF1KA1 SVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
:.:: .:.::...:. .:
CCDS76 SAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST
1880 1890 1900 1910 1920 1930
>--
initn: 4340 init1: 1492 opt: 1580 Z-score: 1093.2 bits: 215.5 E(32554): 1.4e-54
Smith-Waterman score: 1580; 57.3% identity (73.3% similar) in 480 aa overlap (375-844:2892-3359)
350 360 370 380 390 400
pF1KA1 ERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTP
::: . .: . .: . : :
CCDS76 QHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP
2870 2880 2890 2900 2910 2920
410 420 430 440 450 460
pF1KA1 D--KPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREM
: .: .: .:.:: : : ..: :....:: : ... ::.
CCDS76 DLGQPYSSAVYSLEEQYL-GLALDVDRIKK-----DQEEEED-QGPPCPRLS-----REL
2930 2940 2950 2960
470 480 490 500 510
pF1KA1 QKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSSHV
.. : :: .:::..: : :. :: ::. .. ..:: .: .: .: ....
CCDS76 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKG
2970 2980 2990 3000 3010 3020
520 530 540 550 560 570
pF1KA1 EWEDAVHIIPENESDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEM
. . . . : . .: ::...: :: .: .:. : :.: :. ::: : :.
CCDS76 KKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL
3030 3040 3050 3060 3070 3080
580 590 600 610 620 630
pF1KA1 LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQD
: : : :.:. ::.:.: .:::. . . : .:::. . ::::::::::: ::::::
CCDS76 TDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD
3090 3100 3110 3120 3130 3140
640 650 660 670 680 690
pF1KA1 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRL
::::::::::::::::::::::::::::::::::::::::::::::.:::::: ::::::
CCDS76 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRL
3150 3160 3170 3180 3190 3200
700 710 720 730 740 750
pF1KA1 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK
3210 3220 3230 3240 3250 3260
760 770 780 790 800 810
pF1KA1 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSM
::::::::::::::::::::::::::::::::::. :.. . ::::::::: ::::::
CCDS76 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG
3270 3280 3290 3300 3310 3320
820 830 840 850 860
pF1KA1 YFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
:.:: :: : :::.:: .:.::...:. .:
CCDS76 YLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPE
3330 3340 3350 3360 3370 3380
>--
initn: 1989 init1: 1417 opt: 1460 Z-score: 1010.4 bits: 200.2 E(32554): 5.9e-50
Smith-Waterman score: 1593; 61.1% identity (74.2% similar) in 442 aa overlap (451-867:3368-3795)
430 440 450 460 470
pF1KA1 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEE
:. : : :: :. .: :: .:::..
CCDS76 QPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR
3340 3350 3360 3370 3380 3390
480 490 500 510 520 530
pF1KA1 CAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSHVEWEDAVHIIPENESDDEEE
: : :. : .::. .. ..::. . .: . . ..:.:::
CCDS76 CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD--------------VDRIKKDQEEE
3400 3410 3420 3430 3440
540 550 560 570 580 590
pF1KA1 EEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVC
:..:: :: .: : : :: :.: :. ::: : :. : : :.:.:..:::..:
CCDS76 EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG
3450 3460 3470 3480 3490 3500
600 610 620 630
pF1KA1 MAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDS
...:.: :.: . .:::. :::::::::::::::::::
CCDS76 FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDS
3510 3520 3530 3540 3550 3560
640 650 660 670 680 690
pF1KA1 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS
:::::::::: ::: : ::: :: : ::.: .:::.:.:.:.: :: :::: : :::::
CCDS76 LDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS
3570 3580 3590 3600 3610 3620
700 710 720 730 740 750
pF1KA1 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK
::::. :::::::::::::::::. :: :: :::.:. :.:::...:..::: .::::
CCDS76 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKK
3630 3640 3650 3660 3670 3680
760 770 780 790 800 810
pF1KA1 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMY
:::::::::::::::::::::::::::::::::::::::::: :::::::: ::::::::
CCDS76 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMY
3690 3700 3710 3720 3730 3740
820 830 840 850 860
pF1KA1 FELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
:::::::::::::::::::::::::::::::::::::::::::::: :::::
CCDS76 FELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
3750 3760 3770 3780 3790
>--
initn: 1327 init1: 1327 opt: 1327 Z-score: 918.6 bits: 183.2 E(32554): 7.5e-45
Smith-Waterman score: 1327; 85.0% identity (91.8% similar) in 233 aa overlap (581-813:900-1132)
560 570 580 590 600 610
pF1KA1 SEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKE
: :.:. ::.:.: .: :. . . : .:
CCDS76 EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEE
870 880 890 900 910 920
620 630 640 650 660 670
pF1KA1 DQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL
::. . ::::::::::: ::::::::::::::::::::::::::::::::::::::::::
CCDS76 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL
930 940 950 960 970 980
680 690 700 710 720 730
pF1KA1 ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP
::::::::::.:::::: ::::::::::::::::::::::::::::::::::::::::::
CCDS76 ALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP
990 1000 1010 1020 1030 1040
740 750 760 770 780 790
pF1KA1 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNG
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::.
CCDS76 YGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR
1050 1060 1070 1080 1090 1100
800 810 820 830 840 850
pF1KA1 VLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTL
:.: . ::::::::: ::::::
CCDS76 ELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQ
1110 1120 1130 1140 1150 1160
>--
initn: 1296 init1: 1296 opt: 1297 Z-score: 898.0 bits: 179.4 E(32554): 1.1e-43
Smith-Waterman score: 1297; 91.8% identity (95.2% similar) in 208 aa overlap (606-813:1901-2108)
580 590 600 610 620 630
pF1KA1 ASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDS
: .:::. . ::::::::::: :::::::
CCDS76 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS
1880 1890 1900 1910 1920 1930
640 650 660 670 680 690
pF1KA1 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS
1940 1950 1960 1970 1980 1990
700 710 720 730 740 750
pF1KA1 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS76 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK
2000 2010 2020 2030 2040 2050
760 770 780 790 800 810
pF1KA1 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMY
:::::::::::::::::::::::::::::::::. :.. . ::::::::: ::::::
CCDS76 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC
2060 2070 2080 2090 2100 2110
820 830 840 850 860
pF1KA1 FELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
CCDS76 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEV
2120 2130 2140 2150 2160 2170
>>CCDS72895.1 NBPF9 gene_id:400818|Hs108|chr1 (942 aa)
initn: 6078 init1: 4418 opt: 4422 Z-score: 3062.6 bits: 577.9 E(32554): 2.9e-164
Smith-Waterman score: 5062; 87.7% identity (90.2% similar) in 899 aa overlap (1-824:1-899)
10 20 30 40 50 60
pF1KA1 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKY
::::::: ::::::::::::::::.:::::.:::: ::::.::.:::: ::::.:.::::
CCDS72 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
:::::::: ::::::::::::::::::::::::::::::::::::::::.::::::::::
CCDS72 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAE
::::.:::::::::.:::::::::::::::::::::.: ::::::::::::::::::: :
CCDS72 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL
::::::::::::::::::: :::::::::::::::::::::::::::.::::::.:::.:
CCDS72 KVLESSAPREVQKAEESKVAEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA
::::::::::::::.::::::::::::::::::::::::::::::::::::::::.::::
CCDS72 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA
::::::::::::::.:::: ::::::::::::::::::: ::::::::::::::::::::
CCDS72 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLA
:::::::::::.:::::::::::::::::::::::.:::::::::.::::::::::::::
CCDS72 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
:::::.::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS72 EGCRLAQHLVQKLSPENDNDDDEDVQIEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSHVEWEDAVHIIPENESDDEEEEEK
: ::::::::::::::::::::::::::::: ::::::: ::::::::::::::::::::
CCDS72 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
::::::::::::::::::::::::::: ::::::::::.:::::::::::::::::::::
CCDS72 GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG
550 560 570 580 590 600
610 620 630 640
pF1KA1 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSG---------------
:::::::::::::::::::::::::::::::::::::::::::::
CCDS72 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF
610 620 630 640 650 660
pF1KA1 ------------------------------------------------------------
CCDS72 YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG
670 680 690 700 710 720
650 660 670 680 690 700
pF1KA1 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
CCDS72 YLELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
730 740 750 760 770 780
710 720 730 740 750 760
pF1KA1 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
790 800 810 820 830 840
770 780 790 800 810 820
pF1KA1 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY
850 860 870 880 890 900
830 840 850 860
pF1KA1 RSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
CCDS72 RSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
910 920 930 940
>>CCDS72896.1 NBPF9 gene_id:400818|Hs108|chr1 (1111 aa)
initn: 6681 init1: 4418 opt: 4422 Z-score: 3061.5 bits: 577.9 E(32554): 3.3e-164
Smith-Waterman score: 4947; 86.3% identity (89.6% similar) in 895 aa overlap (1-820:1-895)
10 20 30 40 50 60
pF1KA1 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKY
::::::: ::::::::::::::::.:::::.:::: ::::.::.:::: ::::.:.::::
CCDS72 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
:::::::: ::::::::::::::::::::::::::::::::::::::::.::::::::::
CCDS72 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 RSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAE
::::.:::::::::.:::::::::::::::::::::.: ::::::::::::::::::: :
CCDS72 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL
::::::::::::::::::: :::::::::::::::::::::::::::.::::::.:::.:
CCDS72 KVLESSAPREVQKAEESKVAEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA
::::::::::::::.::::::::::::::::::::::::::::::::::::::::.::::
CCDS72 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA
::::::::::::::.:::: ::::::::::::::::::: ::::::::::::::::::::
CCDS72 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLA
:::::::::::.:::::::::::::::::::::::.:::::::::.::::::::::::::
CCDS72 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
:::::.::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS72 EGCRLAQHLVQKLSPENDNDDDEDVQIEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSHVEWEDAVHIIPENESDDEEEEEK
: ::::::::::::::::::::::::::::: ::::::: ::::::::::::::::::::
CCDS72 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
::::::::::::::::::::::::::: ::::::::::.:::::::::::::::::::::
CCDS72 GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG
550 560 570 580 590 600
610 620 630 640
pF1KA1 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSG---------------
:::::::::::::::::::::::::::::::::::::::::::::
CCDS72 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF
610 620 630 640 650 660
pF1KA1 ------------------------------------------------------------
CCDS72 YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG
670 680 690 700 710 720
650 660 670 680 690 700
pF1KA1 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
CCDS72 YLELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
730 740 750 760 770 780
710 720 730 740 750 760
pF1KA1 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
790 800 810 820 830 840
770 780 790 800 810 820
pF1KA1 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY
:::.::::::::::.::::::::. :.. .:::::::::: :::::: :.::::
CCDS72 SKKKRRRGRKEGEENQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY
850 860 870 880 890 900
830 840 850 860
pF1KA1 RSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
CCDS72 SSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
910 920 930 940 950 960
>--
initn: 1473 init1: 1473 opt: 1473 Z-score: 1027.3 bits: 201.5 E(32554): 6.7e-51
Smith-Waterman score: 1473; 100.0% identity (100.0% similar) in 216 aa overlap (652-867:896-1111)
630 640 650 660 670 680
pF1KA1 ELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ
::::::::::::::::::::::::::::::
CCDS72 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ
870 880 890 900 910 920
690 700 710 720 730 740
pF1KA1 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK
930 940 950 960 970 980
750 760 770 780 790 800
pF1KA1 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVL
990 1000 1010 1020 1030 1040
810 820 830 840 850 860
pF1KA1 QDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 QDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQM
1050 1060 1070 1080 1090 1100
pF1KA1 EVIFPQ
::::::
CCDS72 EVIFPQ
1110
>>CCDS72852.1 NBPF15 gene_id:284565|Hs108|chr1 (670 aa)
initn: 4803 init1: 2851 opt: 2855 Z-score: 1983.8 bits: 377.8 E(32554): 3.5e-104
Smith-Waterman score: 3420; 85.2% identity (86.8% similar) in 629 aa overlap (272-825:1-628)
250 260 270 280 290 300
pF1KA1 VDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAE
::::::::::::::::::::::::.:::::
CCDS72 MVVSAGPLSSEKAEMNILEINEKLRPQLAE
10 20 30
310 320 330 340 350 360
pF1KA1 KKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAE
:::::::::::::.:::: ::::.:.:::::::::::: :::::::::::::::::::::
CCDS72 KKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAE
40 50 60 70 80 90
370 380 390 400 410 420
pF1KA1 ELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAE
::::::::::.:::::::::::::::::::::::.:::::::::.:::::::::::::::
CCDS72 ELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAE
100 110 120 130 140 150
430 440 450 460 470 480
pF1KA1 GCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 GCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAIT
160 170 180 190 200 210
490 500 510 520 530 540
pF1KA1 CSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSHVEWEDAVHIIPENESDDEEEEEKG
::::::::::::::.::::::::::::::: :::::::::::::::::::::::::::::
CCDS72 CSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKG
220 230 240 250 260 270
550 560 570 580 590 600
pF1KA1 PVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 PVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGR
280 290 300 310 320 330
610 620 630 640
pF1KA1 HRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSG----------------
:::::::::::::::::::::::::: :::::::::::::::::
CCDS72 HRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY
340 350 360 370 380 390
pF1KA1 -----------------------------------------------------------Y
:
CCDS72 VLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDY
400 410 420 430 440 450
650 660 670 680 690 700
pF1KA1 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEV
460 470 480 490 500 510
710 720 730 740 750 760
pF1KA1 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
520 530 540 550 560 570
770 780 790 800 810 820
pF1KA1 KKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYR
::.:::::::::.: ::::::: ::::::::::::::::: :::::::::: :::::::
CCDS72 KKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYR
580 590 600 610 620
830 840 850 860
pF1KA1 SVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
CCDS72 SVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
630 640 650 660 670
>>CCDS216.1 NBPF3 gene_id:84224|Hs108|chr1 (633 aa)
initn: 4721 init1: 2650 opt: 2654 Z-score: 1845.5 bits: 352.1 E(32554): 1.8e-96
Smith-Waterman score: 3070; 77.9% identity (86.8% similar) in 620 aa overlap (248-867:37-633)
220 230 240 250 260 270
pF1KA1 CDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAG
:.: .: . ::::::::::::::::::
CCDS21 VQGFQWTLRGPDVETSPFGAPRAASHGVGRHQELRDPT----VPGPTSSATNVSMVVSAG
10 20 30 40 50 60
280 290 300 310 320 330
pF1KA1 PLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDL
: :.:::::::::::.: .:::::.::::::::.::.:::.: ::::.::.: ::.::::
CCDS21 PWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDL
70 80 90 100 110 120
340 350 360 370 380 390
pF1KA1 IKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQH
::::::.:: . ::::::.: ::::::::::::::::::::::::::.::::::::::::
CCDS21 IKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQH
130 140 150 160 170 180
400 410 420 430 440 450
pF1KA1 LQALLTPDKPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSS
::::::::.::.:::.::.:::::::::.::::::::::::.:.::::.:: :::::.
CCDS21 LQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELY
190 200 210 220 230 240
460 470 480 490 500 510
pF1KA1 APREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSH
::::.:::::::::::::::::::::::: : .::::. .:.::::::.::::: ::::
CCDS21 APREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSH
250 260 270 280 290 300
520 530 540 550 560 570
pF1KA1 VEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLAS
:: ::: :::::::: :.:::::::::::::::::::.:::::::: ::::::.: ::
CCDS21 DEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSAS
310 320 330 340 350 360
580 590 600 610 620 630
pF1KA1 YQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLD
::: :::::.::::: .:.::::: :::::::::::.::::::::::: :::::::::
CCDS21 YQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLD
370 380 390 400 410 420
640 650 660 670 680 690
pF1KA1 RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRE
: :::: ::::::: ::: : :::.::.::::::.::.::::::::::::::::::::
CCDS21 RFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRE
430 440 450 460 470 480
700 710 720 730 740 750
pF1KA1 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK
: :::::: ::::::: :::: : : ::::::::: ::.:::.:::::::: ::::
CCDS21 LPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK---
490 500 510 520 530
760 770 780 790 800 810
pF1KA1 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFE
.::::::.::::::: ::::.::::::::::: :::: : ::.
CCDS21 ----------------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQ
540 550 560 570 580
820 830 840 850 860
pF1KA1 LPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
: :::.:::.::::::: .:.:: :::::::::: ::.::: ::::.
CCDS21 LHASFQQYRSAFYSFEEQDVSLALDVDNRFFTLTVIRHHLAFQMGVIFPH
590 600 610 620 630
>>CCDS81275.1 NBPF3 gene_id:84224|Hs108|chr1 (577 aa)
initn: 4646 init1: 2575 opt: 2575 Z-score: 1791.6 bits: 342.0 E(32554): 1.8e-93
Smith-Waterman score: 2991; 78.5% identity (87.2% similar) in 596 aa overlap (272-867:1-577)
250 260 270 280 290 300
pF1KA1 VDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAE
::::::: :.:::::::::::.: .:::::
CCDS81 MVVSAGPWSGEKAEMNILEINKKSRPQLAE
10 20 30
310 320 330 340 350 360
pF1KA1 KKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAE
.::::::::.::.:::.: ::::.::.: ::.::::::::::.:: . ::::::.: :::
CCDS81 NKQQFRNLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAE
40 50 60 70 80 90
370 380 390 400 410 420
pF1KA1 ELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAE
:::::::::::::::::::::::.::::::::::::::::::::.::.:::.::.:::::
CCDS81 ELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAE
100 110 120 130 140 150
430 440 450 460 470 480
pF1KA1 GCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAIT
::::.::::::::::::.:.::::.:: :::::. ::::.:::::::::::::::::::
CCDS81 GCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAIT
160 170 180 190 200 210
490 500 510 520 530 540
pF1KA1 CSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSHVEWEDAVHIIPENESDDEEEEEKG
::::: : .::::. .:.::::::.::::: :::: :: ::: :::::::: :.:::::
CCDS81 CSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKG
220 230 240 250 260 270
550 560 570 580 590 600
pF1KA1 PVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGR
::::::::::::::.:::::::: ::::::.: ::::: :::::.::::: .:.::::
CCDS81 PVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGR
280 290 300 310 320 330
610 620 630 640 650 660
pF1KA1 HRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY
: :::::::::::.::::::::::: :::::::::: :::: ::::::: ::: : :
CCDS81 HWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFY
340 350 360 370 380 390
670 680 690 700 710 720
pF1KA1 SLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC
::.::.::::::.::.::::::::::::::::::::: :::::: ::::::: :::: :
CCDS81 SLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSY
400 410 420 430 440 450
730 740 750 760 770 780
pF1KA1 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ
: ::::::::: ::.:::.:::::::: :::: .::::::
CCDS81 PELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEEDQ
460 470 480 490
790 800 810 820 830 840
pF1KA1 NPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFAL
.::::::: ::::.::::::::::: :::: : ::.: :::.:::.::::::: .:.::
CCDS81 KPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLAL
500 510 520 530 540 550
850 860
pF1KA1 YVDNRFFTLTVTSLHLVFQMEVIFPQ
:::::::::: ::.::: ::::.
CCDS81 DVDNRFFTLTVIRHHLAFQMGVIFPH
560 570
>>CCDS57977.1 NBPF3 gene_id:84224|Hs108|chr1 (563 aa)
initn: 4062 init1: 2283 opt: 2283 Z-score: 1590.4 bits: 304.8 E(32554): 2.9e-82
Smith-Waterman score: 2699; 78.6% identity (86.6% similar) in 537 aa overlap (331-867:46-563)
310 320 330 340 350 360
pF1KA1 EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA
::.::::::::::.:: . ::::::.: ::
CCDS57 GPDVETSPFGAPRAASHGVGRHQELRDPTDYEDCKDLIKSMLRDERLLTEEKLAEELGQA
20 30 40 50 60 70
370 380 390 400 410 420
pF1KA1 EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLA
::::::::::::::::::::::::.::::::::::::::::::::.::.:::.::.::::
CCDS57 EELRQYKVLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLA
80 90 100 110 120 130
430 440 450 460 470 480
pF1KA1 EGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
:::::.::::::::::::.:.::::.:: :::::. ::::.::::::::::::::::::
CCDS57 EGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAI
140 150 160 170 180 190
490 500 510 520 530 540
pF1KA1 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLTGSSSHVEWEDAVHIIPENESDDEEEEEK
:::::: : .::::. .:.::::::.::::: :::: :: ::: :::::::: :.::::
CCDS57 TCSNSHHPCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEK
200 210 220 230 240 250
550 560 570 580 590 600
pF1KA1 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
:::::::::::::::.:::::::: ::::::.: ::::: :::::.::::: .:.:::
CCDS57 GPVSPRNLQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG
260 270 280 290 300 310
610 620 630 640 650 660
pF1KA1 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV
:: :::::::::::.::::::::::: :::::::::: :::: ::::::: ::: :
CCDS57 RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDF
320 330 340 350 360 370
670 680 690 700 710 720
pF1KA1 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
:::.::.::::::.::.::::::::::::::::::::: :::::: ::::::: :::: :
CCDS57 YSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFS
380 390 400 410 420 430
730 740 750 760 770 780
pF1KA1 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED
: ::::::::: ::.:::.:::::::: :::: .:::::
CCDS57 YPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------YQEGEED
440 450 460 470
790 800 810 820 830 840
pF1KA1 QNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA
:.::::::: ::::.::::::::::: :::: : ::.: :::.:::.::::::: .:.:
CCDS57 QKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLA
480 490 500 510 520 530
850 860
pF1KA1 LYVDNRFFTLTVTSLHLVFQMEVIFPQ
: :::::::::: ::.::: ::::.
CCDS57 LDVDNRFFTLTVIRHHLAFQMGVIFPH
540 550 560
>>CCDS72856.1 NBPF20 gene_id:100288142|Hs108|chr1 (5207 aa)
initn: 11743 init1: 1813 opt: 1891 Z-score: 1305.7 bits: 255.3 E(32554): 2.1e-66
Smith-Waterman score: 1935; 52.0% identity (69.0% similar) in 696 aa overlap (189-867:4567-5207)
160 170 180 190 200 210
pF1KA1 FQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPC
::. .: .: .:::..: : :.
CCDS72 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP
4540 4550 4560 4570 4580 4590
220 230 240 250 260 270
pF1KA1 DSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGP
: .::... ..::. .. :: ::: ...:. .. . : :
CCDS72 DLGQPYSSAVYSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCPR----------------
4600 4610 4620 4630
280 290 300 310 320 330
pF1KA1 LSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLI
:: : .::. : :.. ... ..:. : .:. . . :.
CCDS72 LSRE-----LLEVVE---PEV------LQDSLDRCYSTPSSCLELT-------DSCQPYR
4640 4650 4660 4670
340 350 360 370 380 390
pF1KA1 KSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQE-------RELTQLREKLREGRDAS
... :.: . :: .. .:...:. . ..:. ::: . .: . .
CCDS72 SAFYVLEQQ--RVGLAVDM---DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLD
4680 4690 4700 4710 4720 4730
400 410 420 430 440
pF1KA1 RSLNQHLQALLTPD--KPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEV
: . : :: .: .: .:.:: : : ..: :....:: :
CCDS72 RCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALDVDRTKK-----DQEEEED-QGPP
4740 4750 4760 4770 4780
450 460 470 480 490 500
pF1KA1 AEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDS
... ::. .. : :: .:::..: : :. :: ::. .. ..:: .:
CCDS72 CPRLS-----RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
4790 4800 4810 4820 4830 4840
510 520 530 540 550 560
pF1KA1 TL-TG---SSSHVEWEDAVHIIPENESDDEE-EEEKGPVSPRNLQESEEEEVP---QESW
.: .: .... . . . . : . .: ::...: :: .: .:. : :.:
CCDS72 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL
4850 4860 4870 4880 4890 4900
570 580 590 600 610 620
pF1KA1 DEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSR
:. ::: : :. : : : :.:. ::.:.: .:::. . . : .:::. . :::::
CCDS72 DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSR
4910 4920 4930 4940 4950 4960
630 640 650 660 670 680
pF1KA1 ELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ
:::::: :::::::::::::::::::::::::::::::::::::::::::::::: ::::
CCDS72 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQ
4970 4980 4990 5000 5010 5020
690 700 710 720 730 740
pF1KA1 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK
5030 5040 5050 5060 5070 5080
750 760 770 780 790 800
pF1KA1 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVL
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
CCDS72 HVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVL
5090 5100 5110 5120 5130 5140
810 820 830 840 850 860
pF1KA1 QDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 QDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQM
5150 5160 5170 5180 5190 5200
pF1KA1 EVIFPQ
:::::
CCDS72 GVIFPQ
>--
initn: 13189 init1: 1510 opt: 1586 Z-score: 1095.3 bits: 216.3 E(32554): 1.1e-54
Smith-Waterman score: 1650; 43.9% identity (64.2% similar) in 768 aa overlap (147-844:3693-4452)
120 130 140 150 160 170
pF1KA1 RDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLF-----QKLSPENDEDED
.:...:. .. : :... : ::
CCDS72 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI
3670 3680 3690 3700 3710 3720
180 190 200 210 220
pF1KA1 EDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIN
: : :.:. . : :: :. .: .: .:::..: : :. : .::...
CCDS72 EKYQ--EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV
3730 3740 3750 3760 3770 3780
230 240 250 260 270 280
pF1KA1 ITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNV--SMVVSAGPLSSEKAEM
..::. .. :: ::: ...:. .. . : : . .: :.. . ..
CCDS72 YSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS
3790 3800 3810 3820 3830
290 300 310 320 330 340
pF1KA1 NILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNER
. :: .. .: ..: :.:: .: ....: : .. . : :...
CCDS72 SCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK
3840 3850 3860 3870 3880 3890
350 360 370 380 390
pF1KA1 QFKEEKLAEQLKQAEELRQYK---VLVHSQERELT------QLREKLREGRDASRSLNQH
. .:.. . ..:: . : :: : .: . .: .. . :.: :.:.
CCDS72 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ
3900 3910 3920 3930 3940 3950
400 410 420 430 440
pF1KA1 LQALLTPDKPDKSQGQDLQEQLAEGC-RLTQHLVQKLSPE--NDNDD-------------
.. :. : . . :...:. .: ::...:... :: .:. :
CCDS72 -RVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP
3960 3970 3980 3990 4000 4010
450 460 470
pF1KA1 ----------------------DEDVQVEVAEKVQKSSAP-----REMQKAEEKEVPEDS
: : . :. . .. : ::. .. : :: .::
CCDS72 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS
4020 4030 4040 4050 4060 4070
480 490 500 510 520 530
pF1KA1 LEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSSHVEWEDAVHIIPEN
:..: : :. :: ::. .. ..:: .: .: .: .... . . . . :
CCDS72 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER
4080 4090 4100 4110 4120 4130
540 550 560 570 580
pF1KA1 ESDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQSYSSTFH
. .: ::.. : :: .: .:. : :.: :. ::: : :. : : : :.:.
CCDS72 RRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFY
4140 4150 4160 4170 4180 4190
590 600 610 620 630 640
pF1KA1 SLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGY
::.:.: .:::. . . : .:::. . ::::::::::: ::::::::::::::::::
CCDS72 VLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY
4200 4210 4220 4230 4240 4250
650 660 670 680 690 700
pF1KA1 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEV
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
CCDS72 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV
4260 4270 4280 4290 4300 4310
710 720 730 740 750 760
pF1KA1 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
4320 4330 4340 4350 4360 4370
770 780 790 800 810 820
pF1KA1 KKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYR
::::::::::::::::::::::. :.. .:::::::::: :::::: :.:::: : :
CCDS72 KKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS
4380 4390 4400 4410 4420 4430
830 840 850 860
pF1KA1 SVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
:. ::.:::....:: ::
CCDS72 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
4440 4450 4460 4470 4480 4490
>--
initn: 14605 init1: 1482 opt: 1568 Z-score: 1082.9 bits: 214.1 E(32554): 5.4e-54
Smith-Waterman score: 1637; 43.4% identity (64.3% similar) in 768 aa overlap (147-844:1253-2012)
120 130 140 150 160 170
pF1KA1 RDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLF-----QKLSPENDEDED
.:...:. .. : :... : ::
CCDS72 RLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI
1230 1240 1250 1260 1270 1280
180 190 200 210 220
pF1KA1 EDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIN
: : :.:. . : :: :. .: .: .:::..: : :. : .::...
CCDS72 EKYQ--EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV
1290 1300 1310 1320 1330 1340
230 240 250 260 270 280
pF1KA1 ITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNV--SMVVSAGPLSSEKAEM
..::. .. :: ::: ...:. .. . : : . .: :.. . ..
CCDS72 YSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS
1350 1360 1370 1380 1390
290 300 310 320 330 340
pF1KA1 NILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNER
. :: .. .: ..: :.:: .: ....: : .. . : :...
CCDS72 SCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK
1400 1410 1420 1430 1440 1450
350 360 370 380 390
pF1KA1 QFKEEKLAEQLKQAEELRQYK---VLVHSQERELT------QLREKLREGRDASRSLNQH
. .:.. . ..:: . : :: : .: . .: .. . :.: :.:.
CCDS72 EGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQ
1460 1470 1480 1490 1500 1510
400 410 420 430 440
pF1KA1 LQALLTPDKPDKSQGQDLQEQLAEGC-RLTQHLVQKLSPE--NDNDD-------------
.. :. : . . :...:. .: ::...:... :: .:. :
CCDS72 -RVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP
1520 1530 1540 1550 1560 1570
450 460 470
pF1KA1 ----------------------DEDVQVEVAEKVQKSSAP-----REMQKAEEKEVPEDS
: : . :. . .. : ::. .. : :: .::
CCDS72 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS
1580 1590 1600 1610 1620 1630
480 490 500 510 520 530
pF1KA1 LEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSSHVEWEDAVHIIPEN
:..: : :. :: ::. .. ..:: .: .: .: .... . . . . :
CCDS72 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER
1640 1650 1660 1670 1680 1690
540 550 560 570 580
pF1KA1 ESDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQSYSSTFH
. .: ::...: :: .: .:. : :.: :..::: : :. : : : :.:.
CCDS72 RRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFY
1700 1710 1720 1730 1740 1750
590 600 610 620 630 640
pF1KA1 SLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGY
::.:.: .:::. . . : .:::. . ::::::::::: ::::::::::::::::::
CCDS72 VLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY
1760 1770 1780 1790 1800 1810
650 660 670 680 690 700
pF1KA1 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEV
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
CCDS72 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV
1820 1830 1840 1850 1860 1870
710 720 730 740 750 760
pF1KA1 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
1880 1890 1900 1910 1920 1930
770 780 790 800 810 820
pF1KA1 KKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYR
::::::::::::::::::::::. :.. . ::::::::: :::::: .:: :: : ::
CCDS72 KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYR
1940 1950 1960 1970 1980 1990
830 840 850 860
pF1KA1 SVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
:.:: .:.:....:. .:
CCDS72 SAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST
2000 2010 2020 2030 2040 2050
>--
initn: 6475 init1: 1482 opt: 1568 Z-score: 1082.9 bits: 214.1 E(32554): 5.4e-54
Smith-Waterman score: 1633; 43.4% identity (64.3% similar) in 768 aa overlap (147-844:33-792)
120 130 140 150 160 170
pF1KA1 RDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLF-----QKLSPENDEDED
.:...:. .. : :... : ::
CCDS72 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEI
10 20 30 40 50 60
180 190 200 210 220
pF1KA1 EDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIN
: : :.:. . : :: :. .: .: .:::..: : :. : .::...
CCDS72 EKYQ--EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV
70 80 90 100 110 120
230 240 250 260 270 280
pF1KA1 ITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNV--SMVVSAGPLSSEKAEM
..::. .. :: ::: ...:. .. . : : . .: :.. . ..
CCDS72 YSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS
130 140 150 160 170
290 300 310 320 330 340
pF1KA1 NILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNER
. :: .. .: ..: :.:: .: ....: : .. . : :...
CCDS72 SCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK
180 190 200 210 220 230
350 360 370 380 390
pF1KA1 QFKEEKLAEQLKQAEELRQYK---VLVHSQERELT------QLREKLREGRDASRSLNQH
. .:.. . ..:: . : :: : .: . .: .. . :.: :.:.
CCDS72 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ
240 250 260 270 280 290
400 410 420 430 440
pF1KA1 LQALLTPDKPDKSQGQDLQEQLAEGC-RLTQHLVQKLSPE--NDNDD-------------
.. :. : . . :...:. .: ::...:... :: .:. :
CCDS72 -RVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP
300 310 320 330 340 350
450 460 470
pF1KA1 ----------------------DEDVQVEVAEKVQKSSAP-----REMQKAEEKEVPEDS
: : . :. . .. : ::. .. : :: .::
CCDS72 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS
360 370 380 390 400 410
480 490 500 510 520 530
pF1KA1 LEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSSHVEWEDAVHIIPEN
:..: : :. :: ::. .. ..:: .: .: .: .... . . . . :
CCDS72 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER
420 430 440 450 460 470
540 550 560 570 580
pF1KA1 ESDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQSYSSTFH
. .: ::...: :: .: .:. : :.: :..::: : :. : : : :.:.
CCDS72 RRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFY
480 490 500 510 520 530
590 600 610 620 630 640
pF1KA1 SLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGY
::.:.: .:::. . . : .:::. . ::::::::::: ::::::::::::::::::
CCDS72 VLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGY
540 550 560 570 580 590
650 660 670 680 690 700
pF1KA1 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEV
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
CCDS72 LELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEV
600 610 620 630 640 650
710 720 730 740 750 760
pF1KA1 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS
660 670 680 690 700 710
770 780 790 800 810 820
pF1KA1 KKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYR
::::::::::::::::::::::. :.. . ::::::::: :::::: .:: :: : ::
CCDS72 KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYR
720 730 740 750 760 770
830 840 850 860
pF1KA1 SVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
:.:: .:.:....:. .:
CCDS72 SAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST
780 790 800 810 820 830
>--
initn: 8655 init1: 1479 opt: 1563 Z-score: 1079.4 bits: 213.4 E(32554): 8.4e-54
Smith-Waterman score: 1563; 57.1% identity (73.1% similar) in 480 aa overlap (375-844:2033-2500)
350 360 370 380 390 400
pF1KA1 ERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTP
::: . .: . .: . : :
CCDS72 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP
2010 2020 2030 2040 2050 2060
410 420 430 440 450 460
pF1KA1 D--KPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREM
: .: .: .:.:: : : ..: :....:: : ... ::.
CCDS72 DLGQPYSSAVYSLEEQYL-GLALDVDRTKK-----DQEEEED-QGPPCPRLS-----REL
2070 2080 2090 2100 2110
470 480 490 500 510
pF1KA1 QKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSSHV
.. : :: .:::..: : :. :: ::. .. ..:: .: .: .: ....
CCDS72 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKG
2120 2130 2140 2150 2160 2170
520 530 540 550 560 570
pF1KA1 EWEDAVHIIPENESDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEM
. . . . : . .: ::...: :: .: .:. : :.: :. ::: : :.
CCDS72 KKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL
2180 2190 2200 2210 2220 2230
580 590 600 610 620 630
pF1KA1 LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQD
: : : :.:. ::.:.: .:::. . . : .:::. . ::::::::::: ::::::
CCDS72 TDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD
2240 2250 2260 2270 2280 2290
640 650 660 670 680 690
pF1KA1 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRL
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
CCDS72 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRL
2300 2310 2320 2330 2340 2350
700 710 720 730 740 750
pF1KA1 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK
2360 2370 2380 2390 2400 2410
760 770 780 790 800 810
pF1KA1 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSM
::::::::::::::::::::::::::::::::::. :.. . ::::::::: ::::::
CCDS72 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG
2420 2430 2440 2450 2460 2470
820 830 840 850 860
pF1KA1 YFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
.:: :: : :::.:: .:.:....:. .:
CCDS72 CLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPE
2480 2490 2500 2510 2520 2530
>--
initn: 5725 init1: 1468 opt: 1554 Z-score: 1073.2 bits: 212.3 E(32554): 1.9e-53
Smith-Waterman score: 1603; 43.9% identity (64.8% similar) in 735 aa overlap (175-844:2504-3232)
150 160 170 180 190 200
pF1KA1 QEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPE
. .:.:. . : :: :. .: .: .
CCDS72 LTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ
2480 2490 2500 2510 2520 2530
210 220 230 240 250 260
pF1KA1 DSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVP
:::..: : :. : .::... ..::. .. :: ::: ...:. .. . : :
CCDS72 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR-TKKDQEEEEDQGPPCP
2540 2550 2560 2570 2580 2590
270 280 290 300 310
pF1KA1 GPTSSATNV--SMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLA
. .: :.. . .. . :: .. .: ..: :.:: .:
CCDS72 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLD
2600 2610 2620 2630 2640
320 330 340 350 360 370
pF1KA1 CFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYK---VLVHSQERE
....: : .. . : :.... .:.. . ..:: . : :: : .:
CCDS72 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRS
2650 2660 2670 2680 2690 2700
380 390 400 410 420
pF1KA1 LT------QLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGC-RLTQHL
. .: .. . :.: :.:. .. :. : . . :...:. .: ::...:
CCDS72 YSTPSGCLELTDSCQPYRSAFYVLEQQ-RVGLAVDMDEIEKYQEVEEDQDPSCPRLSREL
2710 2720 2730 2740 2750 2760
430 440 450
pF1KA1 VQKLSPE--NDNDD-----------------------------------DEDVQVEVAEK
... :: .:. : : : . :.
CCDS72 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEE
2770 2780 2790 2800 2810 2820
460 470 480 490 500
pF1KA1 VQKSSAP-----REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV
. .. : ::. .. : :: .:::..: : :. :: ::. .. ..:: .:
CCDS72 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV
2830 2840 2850 2860 2870 2880
510 520 530 540 550
pF1KA1 DSTL-TG---SSSHVEWEDAVHIIPENESDDEE-EEEKGPVSPRNLQESEEEEVP---QE
.: .: .... . . . . : . .: ::...: :: .: .:. : :.
CCDS72 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD
2890 2900 2910 2920 2930 2940
560 570 580 590 600 610
pF1KA1 SWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRL
: :..::: : :. : : : :.:. ::.:.: .:::. . . : .:::. . :::
CCDS72 SLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRL
2950 2960 2970 2980 2990 3000
620 630 640 650 660 670
pF1KA1 SRELLDEKGPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS72 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKK
3010 3020 3030 3040 3050 3060
680 690 700 710 720 730
pF1KA1 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE
3070 3080 3090 3100 3110 3120
740 750 760 770 780 790
pF1KA1 EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPE
:::::::::::::::::::::::::::::::::::::::::::::::::. :.. . ::
CCDS72 EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE
3130 3140 3150 3160 3170 3180
800 810 820 830 840 850
pF1KA1 VLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVF
::::::: ::::: .:: :: : :::.:: .:.:....:. .:
CCDS72 VLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPS
3190 3200 3210 3220 3230 3240
860
pF1KA1 QMEVIFPQ
CCDS72 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD
3250 3260 3270 3280 3290 3300
>--
initn: 2249 init1: 1402 opt: 1478 Z-score: 1020.8 bits: 202.6 E(32554): 1.5e-50
Smith-Waterman score: 1478; 58.1% identity (73.4% similar) in 451 aa overlap (375-813:3253-3689)
350 360 370 380 390 400
pF1KA1 ERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREK--LREGRDASRSLNQHLQALL
::: . .: :... : : . :
CCDS72 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL-
3230 3240 3250 3260 3270 3280
410 420 430 440 450 460
pF1KA1 TPD--KPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
:: .: .: .:.:: : : ..: :....:: : ... :
CCDS72 -PDLGQPYSSAVYSLEEQYL-GLALDVDRTKK-----DQEEEED-QGPPCPRLS-----R
3290 3300 3310 3320
470 480 490 500 510
pF1KA1 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSS
:. .. : :: .:::..: : :. :: ::. .. ..:: .: .: .: ...
CCDS72 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG
3330 3340 3350 3360 3370 3380
520 530 540 550 560 570
pF1KA1 HVEWEDAVHIIPENESDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPP
. . . . . : . .: ::...: :: .: .:. : :.: :..::: :
CCDS72 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCL
3390 3400 3410 3420 3430 3440
580 590 600 610 620 630
pF1KA1 EMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVL
:. : : : :.:. ::.:.: .:::. . . : .:::. . ::::::::::: ::::
CCDS72 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL
3450 3460 3470 3480 3490 3500
640 650 660 670 680 690
pF1KA1 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCP
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
CCDS72 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCP
3510 3520 3530 3540 3550 3560
700 710 720 730 740 750
pF1KA1 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEI
3570 3580 3590 3600 3610 3620
760 770 780 790 800 810
pF1KA1 EKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTP
::::::::::::::::::::::::::::::::::::. :.. . ::::::::: :::::
CCDS72 EKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTP
3630 3640 3650 3660 3670 3680
820 830 840 850 860
pF1KA1 SMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
:
CCDS72 SGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE
3690 3700 3710 3720 3730 3740
>--
initn: 2249 init1: 1388 opt: 1464 Z-score: 1011.1 bits: 200.8 E(32554): 5.3e-50
Smith-Waterman score: 1464; 57.9% identity (73.2% similar) in 451 aa overlap (375-813:813-1249)
350 360 370 380 390 400
pF1KA1 ERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREK--LREGRDASRSLNQHLQALL
::: . .: :... : : . :
CCDS72 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL-
790 800 810 820 830 840
410 420 430 440 450 460
pF1KA1 TPD--KPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
:: .: .: .:.:: : : ..: :....:: : ... :
CCDS72 -PDLGQPYSSAVYSLEEQYL-GLALDVDRTKK-----DQEEEED-QGPPCPRLS-----R
850 860 870 880
470 480 490 500 510
pF1KA1 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-TG---SSS
:. .. : :: .:::..: : :. :: ::. .. ..:: .: .: .: ...
CCDS72 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG
890 900 910 920 930 940
520 530 540 550 560 570
pF1KA1 HVEWEDAVHIIPENESDDEE-EEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPP
. . . . . : . .: ::...: :: .: .:. : :.: :..::: :
CCDS72 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCL
950 960 970 980 990 1000
580 590 600 610 620 630
pF1KA1 EMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVL
:. : : : :.:. ::.:.: .:::. . . : .:::. . ::::::::::: ::::
CCDS72 ELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL
1010 1020 1030 1040 1050 1060
640 650 660 670 680 690
pF1KA1 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCP
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
CCDS72 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCP
1070 1080 1090 1100 1110 1120
700 710 720 730 740 750
pF1KA1 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEI
1130 1140 1150 1160 1170 1180
760 770 780 790 800 810
pF1KA1 EKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTP
::::::::::::::::::::::::::::::::::::. :.. . ::::::::: ::::
CCDS72 EKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTP
1190 1200 1210 1220 1230 1240
820 830 840 850 860
pF1KA1 SMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ
:
CCDS72 SGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE
1250 1260 1270 1280 1290 1300
>--
initn: 1242 init1: 780 opt: 786 Z-score: 543.4 bits: 114.2 E(32554): 6e-24
Smith-Waterman score: 786; 98.2% identity (99.1% similar) in 114 aa overlap (676-789:4453-4566)
650 660 670 680 690 700
pF1KA1 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
: ::::::::::::::::::::::::::::
CCDS72 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPE
4430 4440 4450 4460 4470 4480
710 720 730 740 750 760
pF1KA1 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
4490 4500 4510 4520 4530 4540
770 780 790 800 810 820
pF1KA1 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY
:::::::::::::::::::::::.
CCDS72 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY
4550 4560 4570 4580 4590 4600
867 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:54:02 2016 done: Sat Nov 5 06:54:03 2016
Total Scan time: 4.950 Total Display time: 0.620
Function used was FASTA [36.3.4 Apr, 2011]