Result of FASTA (omim) for
pF1KA1664
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1664, 916 aa
1>>>pF1KA1664 916 - 916 aa - 916 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4313+/-0.000416; mu= 3.1972+/- 0.026
mean_var=280.9062+/-57.631, 0's: 0 Z-trim(119.7): 129 B-trim: 133 in 1/59
Lambda= 0.076523
statistics sampled from 33850 (33982) to 33850 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.398), width: 16
Scan time: 12.190
The best scores are: opt bits E(85289)
NP_110385 (OMIM: 606729) oxysterol-binding protein ( 916) 6144 692.7 2.2e-198
NP_001269668 (OMIM: 606729) oxysterol-binding prot ( 915) 6127 690.8 8e-198
XP_011528361 (OMIM: 606729) PREDICTED: oxysterol-b ( 819) 4857 550.6 1.2e-155
XP_016884198 (OMIM: 606729) PREDICTED: oxysterol-b ( 818) 4840 548.7 4.3e-155
XP_016884199 (OMIM: 606729) PREDICTED: oxysterol-b ( 743) 4698 533.0 2.1e-150
NP_001269667 (OMIM: 606729) oxysterol-binding prot ( 750) 4681 531.1 7.9e-150
XP_011528362 (OMIM: 606729) PREDICTED: oxysterol-b ( 658) 4245 482.9 2.2e-135
NP_001269670 (OMIM: 606729) oxysterol-binding prot ( 659) 4233 481.6 5.5e-135
XP_006724270 (OMIM: 606729) PREDICTED: oxysterol-b ( 550) 3728 425.8 2.9e-118
XP_011528364 (OMIM: 606729) PREDICTED: oxysterol-b ( 550) 3728 425.8 2.9e-118
NP_001269669 (OMIM: 606729) oxysterol-binding prot ( 549) 3711 423.9 1.1e-117
XP_016884201 (OMIM: 606729) PREDICTED: oxysterol-b ( 549) 3711 423.9 1.1e-117
XP_016884197 (OMIM: 606729) PREDICTED: oxysterol-b ( 867) 3244 372.5 5e-102
XP_005261522 (OMIM: 606729) PREDICTED: oxysterol-b ( 874) 3244 372.5 5e-102
XP_011528359 (OMIM: 606729) PREDICTED: oxysterol-b ( 906) 3241 372.2 6.5e-102
XP_006724266 (OMIM: 606729) PREDICTED: oxysterol-b ( 866) 3227 370.6 1.8e-101
XP_011528360 (OMIM: 606729) PREDICTED: oxysterol-b ( 905) 3224 370.3 2.4e-101
XP_006724271 (OMIM: 606729) PREDICTED: oxysterol-b ( 461) 3133 360.0 1.5e-98
NP_001269671 (OMIM: 606729) oxysterol-binding prot ( 460) 3116 358.1 5.7e-98
XP_016884202 (OMIM: 606729) PREDICTED: oxysterol-b ( 541) 2944 339.2 3.3e-92
XP_011528363 (OMIM: 606729) PREDICTED: oxysterol-b ( 451) 2851 328.8 3.6e-89
XP_016884200 (OMIM: 606729) PREDICTED: oxysterol-b ( 590) 2574 298.4 7e-80
NP_002547 (OMIM: 167040) oxysterol-binding protein ( 807) 1962 230.9 1.9e-59
NP_001229437 (OMIM: 606730) oxysterol-binding prot ( 568) 779 100.2 3.1e-20
XP_006722443 (OMIM: 606730) PREDICTED: oxysterol-b ( 925) 779 100.4 4.4e-20
NP_542164 (OMIM: 606730) oxysterol-binding protein ( 950) 779 100.4 4.4e-20
XP_016881019 (OMIM: 606730) PREDICTED: oxysterol-b ( 968) 779 100.4 4.5e-20
XP_016867438 (OMIM: 606732) PREDICTED: oxysterol-b ( 807) 771 99.5 7.3e-20
XP_006715746 (OMIM: 606732) PREDICTED: oxysterol-b ( 820) 771 99.5 7.4e-20
NP_663162 (OMIM: 606732) oxysterol-binding protein ( 820) 771 99.5 7.4e-20
XP_006715745 (OMIM: 606732) PREDICTED: oxysterol-b ( 851) 771 99.5 7.6e-20
NP_663161 (OMIM: 606732) oxysterol-binding protein ( 851) 771 99.5 7.6e-20
XP_016858766 (OMIM: 606734) PREDICTED: oxysterol-b ( 836) 763 98.6 1.4e-19
XP_016858763 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 763 98.6 1.4e-19
XP_016858765 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 763 98.6 1.4e-19
XP_016858764 (OMIM: 606734) PREDICTED: oxysterol-b ( 867) 763 98.6 1.4e-19
XP_016858762 (OMIM: 606734) PREDICTED: oxysterol-b ( 872) 763 98.6 1.4e-19
XP_016858761 (OMIM: 606734) PREDICTED: oxysterol-b ( 892) 763 98.6 1.4e-19
XP_016858760 (OMIM: 606734) PREDICTED: oxysterol-b ( 898) 763 98.6 1.4e-19
NP_001188411 (OMIM: 606734) oxysterol-binding prot ( 898) 763 98.6 1.4e-19
NP_001188410 (OMIM: 606734) oxysterol-binding prot ( 903) 763 98.6 1.5e-19
XP_016858759 (OMIM: 606734) PREDICTED: oxysterol-b ( 903) 763 98.6 1.5e-19
XP_016858758 (OMIM: 606734) PREDICTED: oxysterol-b ( 923) 763 98.6 1.5e-19
XP_016858757 (OMIM: 606734) PREDICTED: oxysterol-b ( 923) 763 98.6 1.5e-19
XP_011508841 (OMIM: 606734) PREDICTED: oxysterol-b ( 928) 763 98.6 1.5e-19
NP_115912 (OMIM: 606734) oxysterol-binding protein ( 934) 763 98.6 1.5e-19
NP_665682 (OMIM: 606734) oxysterol-binding protein ( 938) 763 98.6 1.5e-19
XP_016858756 (OMIM: 606734) PREDICTED: oxysterol-b ( 959) 763 98.6 1.5e-19
NP_001188409 (OMIM: 606734) oxysterol-binding prot ( 959) 763 98.6 1.5e-19
XP_016858755 (OMIM: 606734) PREDICTED: oxysterol-b ( 959) 763 98.6 1.5e-19
>>NP_110385 (OMIM: 606729) oxysterol-binding protein 2 i (916 aa)
initn: 6144 init1: 6144 opt: 6144 Z-score: 3682.7 bits: 692.7 E(85289): 2.2e-198
Smith-Waterman score: 6144; 99.9% identity (100.0% similar) in 916 aa overlap (1-916:1-916)
10 20 30 40 50 60
pF1KA1 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHAAAPGMSASTSGSGPEPKPQPQPVPEP
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_110 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 SAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 SAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 KQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 KQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGY
850 860 870 880 890 900
910
pF1KA1 WEAKEKQDWHMCPNIF
::::::::::::::::
NP_110 WEAKEKQDWHMCPNIF
910
>>NP_001269668 (OMIM: 606729) oxysterol-binding protein (915 aa)
initn: 3113 init1: 3113 opt: 6127 Z-score: 3672.6 bits: 690.8 E(85289): 8e-198
Smith-Waterman score: 6127; 99.8% identity (99.9% similar) in 916 aa overlap (1-916:1-915)
10 20 30 40 50 60
pF1KA1 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHAAAPGMSASTSGSGPEPKPQPQPVPEP
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
NP_001 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_001 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKED-RKAEGST
430 440 450 460 470
490 500 510 520 530 540
pF1KA1 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA1 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA1 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA1 SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTL
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA1 SAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA1 KQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGY
840 850 860 870 880 890
910
pF1KA1 WEAKEKQDWHMCPNIF
::::::::::::::::
NP_001 WEAKEKQDWHMCPNIF
900 910
>>XP_011528361 (OMIM: 606729) PREDICTED: oxysterol-bindi (819 aa)
initn: 4854 init1: 4854 opt: 4857 Z-score: 2915.4 bits: 550.6 E(85289): 1.2e-155
Smith-Waterman score: 4857; 95.1% identity (97.0% similar) in 775 aa overlap (1-772:1-769)
10 20 30 40 50 60
pF1KA1 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHAAAPGMSASTSGSGPEPKPQPQPVPEP
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
XP_011 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
670 680 690 700 710 720
730 740 750 760 770
pF1KA1 SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQ-MECSKVMHSSPSS--PSSDGKQKTVY
:::::::::: .:. .: .. : : . .. . .: . :..::.
XP_011 SYFSKEAARK------GERGEHVLLLRAGPDPQRARGGRSANRQPPAARPAADGEGPLGR
730 740 750 760 770
780 790 800 810 820 830
pF1KA1 QTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEA
XP_011 GQYREAAAGGEAAPVAAPAAGGLRAGQQLQLGGREGGGCLHATVV
780 790 800 810
>>XP_016884198 (OMIM: 606729) PREDICTED: oxysterol-bindi (818 aa)
initn: 3279 init1: 3113 opt: 4840 Z-score: 2905.3 bits: 548.7 E(85289): 4.3e-155
Smith-Waterman score: 4840; 95.0% identity (96.9% similar) in 775 aa overlap (1-772:1-768)
10 20 30 40 50 60
pF1KA1 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHAAAPGMSASTSGSGPEPKPQPQPVPEP
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
XP_016 MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKED-RKAEGST
430 440 450 460 470
490 500 510 520 530 540
pF1KA1 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA1 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA1 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA1 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
660 670 680 690 700 710
730 740 750 760 770
pF1KA1 SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQ-MECSKVMHSSPSS--PSSDGKQKTVY
:::::::::: .:. .: .. : : . .. . .: . :..::.
XP_016 SYFSKEAARK------GERGEHVLLLRAGPDPQRARGGRSANRQPPAARPAADGEGPLGR
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA1 QTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEA
XP_016 GQYREAAAGGEAAPVAAPAAGGLRAGQQLQLGGREGGGCLHATVV
780 790 800 810
>>XP_016884199 (OMIM: 606729) PREDICTED: oxysterol-bindi (743 aa)
initn: 4698 init1: 4698 opt: 4698 Z-score: 2821.1 bits: 533.0 E(85289): 2.1e-150
Smith-Waterman score: 4698; 100.0% identity (100.0% similar) in 702 aa overlap (215-916:42-743)
190 200 210 220 230 240
pF1KA1 FEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGIL
::::::::::::::::::::::::::::::
XP_016 NRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGIL
20 30 40 50 60 70
250 260 270 280 290 300
pF1KA1 LTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHH
80 90 100 110 120 130
310 320 330 340 350 360
pF1KA1 TLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITS
140 150 160 170 180 190
370 380 390 400 410 420
pF1KA1 NAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRP
200 210 220 230 240 250
430 440 450 460 470 480
pF1KA1 ANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSS
260 270 280 290 300 310
490 500 510 520 530 540
pF1KA1 VDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNF
320 330 340 350 360 370
550 560 570 580 590 600
pF1KA1 NEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLG
380 390 400 410 420 430
610 620 630 640 650 660
pF1KA1 ETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLG
440 450 460 470 480 490
670 680 690 700 710 720
pF1KA1 AIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFS
500 510 520 530 540 550
730 740 750 760 770 780
pF1KA1 KEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKL
560 570 580 590 600 610
790 800 810 820 830 840
pF1KA1 LWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRL
620 630 640 650 660 670
850 860 870 880 890 900
pF1KA1 EEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAK
680 690 700 710 720 730
910
pF1KA1 EKQDWHMCPNIF
::::::::::::
XP_016 EKQDWHMCPNIF
740
>>NP_001269667 (OMIM: 606729) oxysterol-binding protein (750 aa)
initn: 3033 init1: 3033 opt: 4681 Z-score: 2810.9 bits: 531.1 E(85289): 7.9e-150
Smith-Waterman score: 4681; 99.9% identity (99.9% similar) in 702 aa overlap (215-916:50-750)
190 200 210 220 230 240
pF1KA1 FEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGIL
::::::::::::::::::::::::::::::
NP_001 NRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGIL
20 30 40 50 60 70
250 260 270 280 290 300
pF1KA1 LTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHH
80 90 100 110 120 130
310 320 330 340 350 360
pF1KA1 TLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITS
140 150 160 170 180 190
370 380 390 400 410 420
pF1KA1 NAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRP
200 210 220 230 240 250
430 440 450 460 470 480
pF1KA1 ANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSS
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_001 ANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKED-RKAEGSTGTSS
260 270 280 290 300 310
490 500 510 520 530 540
pF1KA1 VDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNF
320 330 340 350 360 370
550 560 570 580 590 600
pF1KA1 NEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLG
380 390 400 410 420 430
610 620 630 640 650 660
pF1KA1 ETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLG
440 450 460 470 480 490
670 680 690 700 710 720
pF1KA1 AIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFS
500 510 520 530 540 550
730 740 750 760 770 780
pF1KA1 KEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKL
560 570 580 590 600 610
790 800 810 820 830 840
pF1KA1 LWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRL
620 630 640 650 660 670
850 860 870 880 890 900
pF1KA1 EEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAK
680 690 700 710 720 730
910
pF1KA1 EKQDWHMCPNIF
::::::::::::
NP_001 EKQDWHMCPNIF
740 750
>>XP_011528362 (OMIM: 606729) PREDICTED: oxysterol-bindi (658 aa)
initn: 4245 init1: 4245 opt: 4245 Z-score: 2551.5 bits: 482.9 E(85289): 2.2e-135
Smith-Waterman score: 4245; 100.0% identity (100.0% similar) in 632 aa overlap (285-916:27-658)
260 270 280 290 300 310
pF1KA1 KASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLD
::::::::::::::::::::::::::::::
XP_011 MKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLD
10 20 30 40 50
320 330 340 350 360 370
pF1KA1 DLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDF
60 70 80 90 100 110
380 390 400 410 420 430
pF1KA1 LELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEG
120 130 140 150 160 170
440 450 460 470 480 490
pF1KA1 SLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVL
180 190 200 210 220 230
500 510 520 530 540 550
pF1KA1 DGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRL
240 250 260 270 280 290
560 570 580 590 600 610
pF1KA1 TEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDD
300 310 320 330 340 350
620 630 640 650 660 670
pF1KA1 MGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASG
360 370 380 390 400 410
680 690 700 710 720 730
pF1KA1 NHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGV
420 430 440 450 460 470
740 750 760 770 780 790
pF1KA1 VSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPEN
480 490 500 510 520 530
800 810 820 830 840 850
pF1KA1 AENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRR
540 550 560 570 580 590
860 870 880 890 900 910
pF1KA1 RLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPN
600 610 620 630 640 650
pF1KA1 IF
::
XP_011 IF
>>NP_001269670 (OMIM: 606729) oxysterol-binding protein (659 aa)
initn: 3933 init1: 3891 opt: 4233 Z-score: 2544.4 bits: 481.6 E(85289): 5.5e-135
Smith-Waterman score: 4233; 99.8% identity (99.8% similar) in 633 aa overlap (285-916:27-659)
260 270 280 290 300 310
pF1KA1 KASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLD
::::::::::::::::::::::::::::::
NP_001 MKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLD
10 20 30 40 50
320 330 340 350 360 370
pF1KA1 DLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDF
60 70 80 90 100 110
380 390 400 410 420 430
pF1KA1 LELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEG
120 130 140 150 160 170
440 450 460 470 480 490
pF1KA1 SLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVL
180 190 200 210 220 230
500 510 520 530 540 550
pF1KA1 DGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRL
240 250 260 270 280 290
560 570 580 590 600 610
pF1KA1 TEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDD
300 310 320 330 340 350
620 630 640 650 660 670
pF1KA1 MGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASG
360 370 380 390 400 410
680 690 700 710 720 730
pF1KA1 NHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGV
420 430 440 450 460 470
740 750 760 770 780 790
pF1KA1 VSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPEN
480 490 500 510 520 530
800 810 820 830 840 850
pF1KA1 AENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRR
540 550 560 570 580 590
860 870 880 890 900 910
pF1KA1 RLEACGPGSSCSSEE-EKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCP
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLEACGPGSSCSSEEAEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCP
600 610 620 630 640 650
pF1KA1 NIF
:::
NP_001 NIF
>>XP_006724270 (OMIM: 606729) PREDICTED: oxysterol-bindi (550 aa)
initn: 3728 init1: 3728 opt: 3728 Z-score: 2244.1 bits: 425.8 E(85289): 2.9e-118
Smith-Waterman score: 3728; 100.0% identity (100.0% similar) in 550 aa overlap (367-916:1-550)
340 350 360 370 380 390
pF1KA1 LDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQR
::::::::::::::::::::::::::::::
XP_006 MINACRDFLELAEIHSRKWQRALQYEQEQR
10 20 30
400 410 420 430 440 450
pF1KA1 VHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAM
40 50 60 70 80 90
460 470 480 490 500 510
pF1KA1 EDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNK
100 110 120 130 140 150
520 530 540 550 560 570
pF1KA1 PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQ
160 170 180 190 200 210
580 590 600 610 620 630
pF1KA1 MCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVF
220 230 240 250 260 270
640 650 660 670 680 690
pF1KA1 SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWI
280 290 300 310 320 330
700 710 720 730 740 750
pF1KA1 DQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMEC
340 350 360 370 380 390
760 770 780 790 800 810
pF1KA1 SKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVA
400 410 420 430 440 450
820 830 840 850 860 870
pF1KA1 PTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAY
460 470 480 490 500 510
880 890 900 910
pF1KA1 TPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF
::::::::::::::::::::::::::::::::::::::::
XP_006 TPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF
520 530 540 550
>>XP_011528364 (OMIM: 606729) PREDICTED: oxysterol-bindi (550 aa)
initn: 3728 init1: 3728 opt: 3728 Z-score: 2244.1 bits: 425.8 E(85289): 2.9e-118
Smith-Waterman score: 3728; 100.0% identity (100.0% similar) in 550 aa overlap (367-916:1-550)
340 350 360 370 380 390
pF1KA1 LDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQR
::::::::::::::::::::::::::::::
XP_011 MINACRDFLELAEIHSRKWQRALQYEQEQR
10 20 30
400 410 420 430 440 450
pF1KA1 VHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAM
40 50 60 70 80 90
460 470 480 490 500 510
pF1KA1 EDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNK
100 110 120 130 140 150
520 530 540 550 560 570
pF1KA1 PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQ
160 170 180 190 200 210
580 590 600 610 620 630
pF1KA1 MCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVF
220 230 240 250 260 270
640 650 660 670 680 690
pF1KA1 SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWI
280 290 300 310 320 330
700 710 720 730 740 750
pF1KA1 DQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMEC
340 350 360 370 380 390
760 770 780 790 800 810
pF1KA1 SKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVA
400 410 420 430 440 450
820 830 840 850 860 870
pF1KA1 PTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAY
460 470 480 490 500 510
880 890 900 910
pF1KA1 TPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF
::::::::::::::::::::::::::::::::::::::::
XP_011 TPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF
520 530 540 550
916 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:38:02 2016 done: Wed Nov 2 21:38:04 2016
Total Scan time: 12.190 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]