Result of FASTA (omim) for
pF1KA1568
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1568, 1378 aa
1>>>pF1KA1568 1378 - 1378 aa - 1378 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2281+/-0.000493; mu= 0.2792+/- 0.031
mean_var=396.3375+/-82.393, 0's: 0 Z-trim(120.0): 564 B-trim: 33 in 1/57
Lambda= 0.064423
statistics sampled from 33973 (34677) to 33973 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.407), width: 16
Scan time: 12.890
The best scores are: opt bits E(85289)
NP_002933 (OMIM: 602431,610878) roundabout homolog (1378) 9310 881.4 0
NP_001276968 (OMIM: 602431,610878) roundabout homo (1382) 9292 879.7 0
XP_016862495 (OMIM: 602431,610878) PREDICTED: roun (1379) 9254 876.2 0
NP_001122401 (OMIM: 602431,610878) roundabout homo (1394) 9179 869.2 0
XP_016862492 (OMIM: 602431,610878) PREDICTED: roun (1401) 9179 869.2 0
XP_016862493 (OMIM: 602431,610878) PREDICTED: roun (1398) 9161 867.5 0
XP_011532287 (OMIM: 602431,610878) PREDICTED: roun (1405) 9161 867.5 0
XP_016862494 (OMIM: 602431,610878) PREDICTED: roun (1396) 9142 865.8 0
XP_016862490 (OMIM: 602431,610878) PREDICTED: roun (1403) 9142 865.8 0
XP_016862491 (OMIM: 602431,610878) PREDICTED: roun (1402) 9123 864.0 0
XP_016862482 (OMIM: 602431,610878) PREDICTED: roun (1469) 8893 842.7 0
XP_016862481 (OMIM: 602431,610878) PREDICTED: roun (1489) 8744 828.8 0
XP_016862480 (OMIM: 602431,610878) PREDICTED: roun (1496) 8744 828.8 0
NP_001276969 (OMIM: 602431,610878) roundabout homo (1443) 8471 803.4 0
XP_011532284 (OMIM: 602431,610878) PREDICTED: roun (1557) 8340 791.3 0
XP_016862476 (OMIM: 602431,610878) PREDICTED: roun (1554) 8323 789.7 0
XP_016862489 (OMIM: 602431,610878) PREDICTED: roun (1420) 7030 669.5 4.8e-191
XP_016862488 (OMIM: 602431,610878) PREDICTED: roun (1422) 7012 667.8 1.5e-190
XP_016862487 (OMIM: 602431,610878) PREDICTED: roun (1424) 7012 667.8 1.5e-190
XP_016862475 (OMIM: 602431,610878) PREDICTED: roun (1576) 7012 667.9 1.7e-190
XP_016862478 (OMIM: 602431,610878) PREDICTED: roun (1534) 6899 657.4 2.4e-187
XP_016862486 (OMIM: 602431,610878) PREDICTED: roun (1438) 6881 655.7 7.2e-187
XP_016862485 (OMIM: 602431,610878) PREDICTED: roun (1440) 6881 655.7 7.2e-187
XP_016862483 (OMIM: 602431,610878) PREDICTED: roun (1445) 6881 655.7 7.2e-187
XP_011532286 (OMIM: 602431,610878) PREDICTED: roun (1447) 6881 655.7 7.2e-187
XP_016862479 (OMIM: 602431,610878) PREDICTED: roun (1531) 6881 655.7 7.5e-187
XP_016862477 (OMIM: 602431,610878) PREDICTED: roun (1536) 6881 655.7 7.5e-187
XP_011532285 (OMIM: 602431,610878) PREDICTED: roun (1538) 6881 655.7 7.5e-187
XP_011532283 (OMIM: 602431,610878) PREDICTED: roun (1597) 6881 655.7 7.7e-187
XP_016862484 (OMIM: 602431,610878) PREDICTED: roun (1442) 6859 653.6 3e-186
NP_001276994 (OMIM: 602431,610878) roundabout homo ( 785) 5318 510.1 2.6e-143
NP_001139317 (OMIM: 602430) roundabout homolog 1 i (1551) 4138 400.7 4.2e-110
XP_011532282 (OMIM: 602430) PREDICTED: roundabout (1590) 4137 400.7 4.6e-110
NP_598334 (OMIM: 602430) roundabout homolog 1 isof (1606) 4100 397.2 5e-109
XP_011532280 (OMIM: 602430) PREDICTED: roundabout (1645) 4099 397.2 5.4e-109
XP_016862472 (OMIM: 602430) PREDICTED: roundabout (1612) 4054 393.0 9.7e-108
NP_002932 (OMIM: 602430) roundabout homolog 1 isof (1651) 4053 392.9 1e-107
XP_016862471 (OMIM: 602430) PREDICTED: roundabout (1626) 4041 391.8 2.2e-107
XP_006713340 (OMIM: 602430) PREDICTED: roundabout (1615) 4033 391.0 3.7e-107
XP_016862473 (OMIM: 602430) PREDICTED: roundabout (1596) 4032 390.9 4e-107
XP_011532279 (OMIM: 602430) PREDICTED: roundabout (1654) 4032 390.9 4.1e-107
XP_011532278 (OMIM: 602430) PREDICTED: roundabout (1654) 4032 390.9 4.1e-107
XP_011532281 (OMIM: 602430) PREDICTED: roundabout (1599) 4017 389.5 1e-106
XP_016862474 (OMIM: 602430) PREDICTED: roundabout (1535) 3612 351.9 2.2e-95
NP_071765 (OMIM: 607313,608630) roundabout homolog (1386) 3375 329.8 8.7e-89
XP_016873611 (OMIM: 607313,608630) PREDICTED: roun (1364) 3372 329.5 1e-88
XP_011524145 (OMIM: 114500,120470,133239,157600) P (1443) 648 76.3 1.8e-12
XP_016881057 (OMIM: 114500,120470,133239,157600) P (1445) 648 76.3 1.8e-12
NP_005206 (OMIM: 114500,120470,133239,157600) netr (1447) 648 76.3 1.8e-12
XP_016877726 (OMIM: 601907) PREDICTED: neogenin is (1394) 626 74.3 7.2e-12
>>NP_002933 (OMIM: 602431,610878) roundabout homolog 2 i (1378 aa)
initn: 9310 init1: 9310 opt: 9310 Z-score: 4696.2 bits: 881.4 E(85289): 0
Smith-Waterman score: 9310; 100.0% identity (100.0% similar) in 1378 aa overlap (1-1378:1-1378)
10 20 30 40 50 60
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 KMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 PQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPII
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 LQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 SDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 QGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 QPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA1 GMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA1 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA1 ITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA1 DGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPPVPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPPVPGQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA1 GDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQW
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA1 KSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPPPPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPPPPVQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KA1 PLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRGVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRGVASS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KA1 PAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQPPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQPPVPP
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KA1 LGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKAFTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKAFTSS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KA1 QRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALVPYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALVPYSK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KA1 PSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTGEL
1330 1340 1350 1360 1370
>>NP_001276968 (OMIM: 602431,610878) roundabout homolog (1382 aa)
initn: 7201 init1: 7201 opt: 9292 Z-score: 4687.1 bits: 879.7 E(85289): 0
Smith-Waterman score: 9292; 99.7% identity (99.7% similar) in 1382 aa overlap (1-1378:1-1382)
10 20 30 40 50 60
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
250 260 270 280 290 300
310 320 330 340 350
pF1KA1 KMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL
:::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 SVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 AINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTW
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 TVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYF
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 NEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 IWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRR
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 NEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVT
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 FQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLP
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 DPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPP
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 PPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQP
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 PVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKA
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 FTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALV
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 PYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTG
1330 1340 1350 1360 1370 1380
pF1KA1 EL
::
NP_001 EL
>>XP_016862495 (OMIM: 602431,610878) PREDICTED: roundabo (1379 aa)
initn: 5001 init1: 4950 opt: 9254 Z-score: 4668.1 bits: 876.2 E(85289): 0
Smith-Waterman score: 9254; 99.5% identity (99.5% similar) in 1382 aa overlap (1-1378:1-1379)
10 20 30 40 50 60
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVG
250 260 270 280 290 300
310 320 330 340 350
pF1KA1 KMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL
:::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKN
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 SVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 AINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTW
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 TVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYF
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 NEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 IWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRR
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 NEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVT
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 FQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLP
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 DPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWANVPLPP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
XP_016 DPQWKSSIQQKTDLMGFGYSLPDQNKG---GKGGKKKKNKNSSKPQKNNGSTWANVPLPP
1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KA1 PPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRG
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KA1 VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQP
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KA1 PVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDSSVTGKA
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KA1 FTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALV
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KA1 PYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNSQGQFTG
1320 1330 1340 1350 1360 1370
pF1KA1 EL
::
XP_016 EL
>>NP_001122401 (OMIM: 602431,610878) roundabout homolog (1394 aa)
initn: 9179 init1: 9179 opt: 9179 Z-score: 4630.3 bits: 869.2 E(85289): 0
Smith-Waterman score: 9179; 100.0% identity (100.0% similar) in 1358 aa overlap (21-1378:37-1394)
10 20 30 40 50
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
::::::::::::::::::::::::::::::
NP_001 RVTRRMWTWAPGLLMMTVVFWGHQGNGQGQGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA1 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA1 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA1 VLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA1 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA1 TDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA1 YLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA1 TVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEI
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA1 KVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA1 IIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA1 IIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA1 SNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGR
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA1 GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA1 LAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWA
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KA1 NVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KA1 TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSN
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KA1 NQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDS
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KA1 SVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMT
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KA1 DEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNS
1330 1340 1350 1360 1370 1380
pF1KA1 QGQFTGEL
::::::::
NP_001 QGQFTGEL
1390
>>XP_016862492 (OMIM: 602431,610878) PREDICTED: roundabo (1401 aa)
initn: 9179 init1: 9179 opt: 9179 Z-score: 4630.3 bits: 869.2 E(85289): 0
Smith-Waterman score: 9179; 100.0% identity (100.0% similar) in 1358 aa overlap (21-1378:44-1401)
10 20 30 40 50
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
::::::::::::::::::::::::::::::
XP_016 ELLFVLMLFLSGPTLSKLTRTPWKGKPWKGGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
80 90 100 110 120 130
120 130 140 150 160 170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
140 150 160 170 180 190
180 190 200 210 220 230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
200 210 220 230 240 250
240 250 260 270 280 290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
260 270 280 290 300 310
300 310 320 330 340 350
pF1KA1 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKE
320 330 340 350 360 370
360 370 380 390 400 410
pF1KA1 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTD
380 390 400 410 420 430
420 430 440 450 460 470
pF1KA1 VLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQ
440 450 460 470 480 490
480 490 500 510 520 530
pF1KA1 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQV
500 510 520 530 540 550
540 550 560 570 580 590
pF1KA1 TDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTI
560 570 580 590 600 610
600 610 620 630 640 650
pF1KA1 YLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPT
620 630 640 650 660 670
660 670 680 690 700 710
pF1KA1 TVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEI
680 690 700 710 720 730
720 730 740 750 760 770
pF1KA1 KVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNG
740 750 760 770 780 790
780 790 800 810 820 830
pF1KA1 IIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQP
800 810 820 830 840 850
840 850 860 870 880 890
pF1KA1 IIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGL
860 870 880 890 900 910
900 910 920 930 940 950
pF1KA1 SNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGR
920 930 940 950 960 970
960 970 980 990 1000 1010
pF1KA1 GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHE
980 990 1000 1010 1020 1030
1020 1030 1040 1050 1060 1070
pF1KA1 LAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNGSTWA
1040 1050 1060 1070 1080 1090
1080 1090 1100 1110 1120 1130
pF1KA1 NVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVP
1100 1110 1120 1130 1140 1150
1140 1150 1160 1170 1180 1190
pF1KA1 TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSN
1160 1170 1180 1190 1200 1210
1200 1210 1220 1230 1240 1250
pF1KA1 NQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMDNLDS
1220 1230 1240 1250 1260 1270
1260 1270 1280 1290 1300 1310
pF1KA1 SVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMT
1280 1290 1300 1310 1320 1330
1320 1330 1340 1350 1360 1370
pF1KA1 DEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYMGSNS
1340 1350 1360 1370 1380 1390
pF1KA1 QGQFTGEL
::::::::
XP_016 QGQFTGEL
1400
>>XP_016862493 (OMIM: 602431,610878) PREDICTED: roundabo (1398 aa)
initn: 7201 init1: 7201 opt: 9161 Z-score: 4621.3 bits: 867.5 E(85289): 0
Smith-Waterman score: 9161; 99.7% identity (99.7% similar) in 1362 aa overlap (21-1378:37-1398)
10 20 30 40 50
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
::::::::::::::::::::::::::::::
XP_016 RVTRRMWTWAPGLLMMTVVFWGHQGNGQGQGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
250 260 270 280 290 300
300 310 320 330 340
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
1330 1340 1350 1360 1370 1380
1370
pF1KA1 GSNSQGQFTGEL
::::::::::::
XP_016 GSNSQGQFTGEL
1390
>>XP_011532287 (OMIM: 602431,610878) PREDICTED: roundabo (1405 aa)
initn: 7201 init1: 7201 opt: 9161 Z-score: 4621.3 bits: 867.5 E(85289): 0
Smith-Waterman score: 9161; 99.7% identity (99.7% similar) in 1362 aa overlap (21-1378:44-1405)
10 20 30 40 50
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
::::::::::::::::::::::::::::::
XP_011 ELLFVLMLFLSGPTLSKLTRTPWKGKPWKGGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
80 90 100 110 120 130
120 130 140 150 160 170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
140 150 160 170 180 190
180 190 200 210 220 230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
200 210 220 230 240 250
240 250 260 270 280 290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
260 270 280 290 300 310
300 310 320 330 340
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
320 330 340 350 360 370
350 360 370 380 390 400
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
380 390 400 410 420 430
410 420 430 440 450 460
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
440 450 460 470 480 490
470 480 490 500 510 520
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
500 510 520 530 540 550
530 540 550 560 570 580
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
560 570 580 590 600 610
590 600 610 620 630 640
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
620 630 640 650 660 670
650 660 670 680 690 700
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
680 690 700 710 720 730
710 720 730 740 750 760
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
740 750 760 770 780 790
770 780 790 800 810 820
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
800 810 820 830 840 850
830 840 850 860 870 880
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
860 870 880 890 900 910
890 900 910 920 930 940
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
920 930 940 950 960 970
950 960 970 980 990 1000
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
980 990 1000 1010 1020 1030
1010 1020 1030 1040 1050 1060
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
1040 1050 1060 1070 1080 1090
1070 1080 1090 1100 1110 1120
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
1100 1110 1120 1130 1140 1150
1130 1140 1150 1160 1170 1180
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
1160 1170 1180 1190 1200 1210
1190 1200 1210 1220 1230 1240
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
1220 1230 1240 1250 1260 1270
1250 1260 1270 1280 1290 1300
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
1280 1290 1300 1310 1320 1330
1310 1320 1330 1340 1350 1360
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
1340 1350 1360 1370 1380 1390
1370
pF1KA1 GSNSQGQFTGEL
::::::::::::
XP_011 GSNSQGQFTGEL
1400
>>XP_016862494 (OMIM: 602431,610878) PREDICTED: roundabo (1396 aa)
initn: 7182 init1: 7182 opt: 9142 Z-score: 4611.7 bits: 865.8 E(85289): 0
Smith-Waterman score: 9142; 99.7% identity (99.7% similar) in 1359 aa overlap (21-1375:37-1395)
10 20 30 40 50
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
::::::::::::::::::::::::::::::
XP_016 RVTRRMWTWAPGLLMMTVVFWGHQGNGQGQGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
250 260 270 280 290 300
300 310 320 330 340
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
310 320 330 340 350 360
350 360 370 380 390 400
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
370 380 390 400 410 420
410 420 430 440 450 460
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
430 440 450 460 470 480
470 480 490 500 510 520
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
490 500 510 520 530 540
530 540 550 560 570 580
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
550 560 570 580 590 600
590 600 610 620 630 640
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
670 680 690 700 710 720
710 720 730 740 750 760
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
730 740 750 760 770 780
770 780 790 800 810 820
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
790 800 810 820 830 840
830 840 850 860 870 880
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
850 860 870 880 890 900
890 900 910 920 930 940
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
1330 1340 1350 1360 1370 1380
1370
pF1KA1 GSNSQGQFTGEL
:::::::::
XP_016 GSNSQGQFTE
1390
>>XP_016862490 (OMIM: 602431,610878) PREDICTED: roundabo (1403 aa)
initn: 7182 init1: 7182 opt: 9142 Z-score: 4611.7 bits: 865.8 E(85289): 0
Smith-Waterman score: 9142; 99.7% identity (99.7% similar) in 1359 aa overlap (21-1375:44-1402)
10 20 30 40 50
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
::::::::::::::::::::::::::::::
XP_016 ELLFVLMLFLSGPTLSKLTRTPWKGKPWKGGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
80 90 100 110 120 130
120 130 140 150 160 170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
140 150 160 170 180 190
180 190 200 210 220 230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
200 210 220 230 240 250
240 250 260 270 280 290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
260 270 280 290 300 310
300 310 320 330 340
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
320 330 340 350 360 370
350 360 370 380 390 400
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
380 390 400 410 420 430
410 420 430 440 450 460
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
440 450 460 470 480 490
470 480 490 500 510 520
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
500 510 520 530 540 550
530 540 550 560 570 580
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
560 570 580 590 600 610
590 600 610 620 630 640
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
620 630 640 650 660 670
650 660 670 680 690 700
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
680 690 700 710 720 730
710 720 730 740 750 760
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
740 750 760 770 780 790
770 780 790 800 810 820
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
800 810 820 830 840 850
830 840 850 860 870 880
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
860 870 880 890 900 910
890 900 910 920 930 940
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
920 930 940 950 960 970
950 960 970 980 990 1000
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
980 990 1000 1010 1020 1030
1010 1020 1030 1040 1050 1060
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
1040 1050 1060 1070 1080 1090
1070 1080 1090 1100 1110 1120
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
1100 1110 1120 1130 1140 1150
1130 1140 1150 1160 1170 1180
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
1160 1170 1180 1190 1200 1210
1190 1200 1210 1220 1230 1240
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
1220 1230 1240 1250 1260 1270
1250 1260 1270 1280 1290 1300
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
1280 1290 1300 1310 1320 1330
1310 1320 1330 1340 1350 1360
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
1340 1350 1360 1370 1380 1390
1370
pF1KA1 GSNSQGQFTGEL
:::::::::
XP_016 GSNSQGQFTE
1400
>>XP_016862491 (OMIM: 602431,610878) PREDICTED: roundabo (1402 aa)
initn: 5001 init1: 4950 opt: 9123 Z-score: 4602.2 bits: 864.0 E(85289): 0
Smith-Waterman score: 9123; 99.5% identity (99.5% similar) in 1362 aa overlap (21-1378:44-1402)
10 20 30 40 50
pF1KA1 MSLLMFTQLLLCGFLYVRVDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
::::::::::::::::::::::::::::::
XP_016 ELLFVLMLFLSGPTLSKLTRTPWKGKPWKGGSRLRQEDFPPRIVEHPSDVIVSKGEPTTL
20 30 40 50 60 70
60 70 80 90 100 110
pF1KA1 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVC
80 90 100 110 120 130
120 130 140 150 160 170
pF1KA1 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD
140 150 160 170 180 190
180 190 200 210 220 230
pF1KA1 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRR
200 210 220 230 240 250
240 250 260 270 280 290
pF1KA1 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKTMSTDEGT
260 270 280 290 300 310
300 310 320 330 340
pF1KA1 YMCIAENRVGKMEASATLTVRA----PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
:::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_016 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVF
320 330 340 350 360 370
350 360 370 380 390 400
pF1KA1 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQL
380 390 400 410 420 430
410 420 430 440 450 460
pF1KA1 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRAT
440 450 460 470 480 490
470 480 490 500 510 520
pF1KA1 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPS
500 510 520 530 540 550
530 540 550 560 570 580
pF1KA1 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLR
560 570 580 590 600 610
590 600 610 620 630 640
pF1KA1 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVV
620 630 640 650 660 670
650 660 670 680 690 700
pF1KA1 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGV
680 690 700 710 720 730
710 720 730 740 750 760
pF1KA1 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD
740 750 760 770 780 790
770 780 790 800 810 820
pF1KA1 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKS
800 810 820 830 840 850
830 840 850 860 870 880
pF1KA1 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKK
860 870 880 890 900 910
890 900 910 920 930 940
pF1KA1 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIG
920 930 940 950 960 970
950 960 970 980 990 1000
pF1KA1 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSN
980 990 1000 1010 1020 1030
1010 1020 1030 1040 1050 1060
pF1KA1 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSSKPQKNNG
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 SIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKG---GKGGKKKKNKNSSKPQKNNG
1040 1050 1060 1070 1080 1090
1070 1080 1090 1100 1110 1120
pF1KA1 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDD
1100 1110 1120 1130 1140 1150
1130 1140 1150 1160 1170 1180
pF1KA1 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWH
1160 1170 1180 1190 1200 1210
1190 1200 1210 1220 1230 1240
pF1KA1 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQTPGSSMD
1220 1230 1240 1250 1260 1270
1250 1260 1270 1280 1290 1300
pF1KA1 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRR
1280 1290 1300 1310 1320 1330
1310 1320 1330 1340 1350 1360
pF1KA1 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNASDLLDIGYM
1340 1350 1360 1370 1380 1390
1370
pF1KA1 GSNSQGQFTGEL
::::::::::::
XP_016 GSNSQGQFTGEL
1400
1378 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:25:46 2016 done: Wed Nov 2 21:25:48 2016
Total Scan time: 12.890 Total Display time: 0.660
Function used was FASTA [36.3.4 Apr, 2011]