FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KA1558, 879 aa 1>>>pF1KA1558 879 - 879 aa - 879 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3785+/-0.000379; mu= 11.4885+/- 0.024 mean_var=121.9645+/-24.255, 0's: 0 Z-trim(116.6): 101 B-trim: 289 in 1/56 Lambda= 0.116133 statistics sampled from 27718 (27820) to 27718 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.326), width: 16 Scan time: 14.790 The best scores are: opt bits E(85289) XP_011543442 (OMIM: 610879) PREDICTED: serine/thre ( 879) 5775 979.3 0 NP_001157632 (OMIM: 610879) serine/threonine-prote ( 879) 5775 979.3 0 XP_016873451 (OMIM: 610879) PREDICTED: serine/thre ( 879) 5775 979.3 0 XP_016873454 (OMIM: 610879) PREDICTED: serine/thre ( 873) 5712 968.7 0 XP_016873453 (OMIM: 610879) PREDICTED: serine/thre ( 873) 5712 968.7 0 XP_016873452 (OMIM: 610879) PREDICTED: serine/thre ( 873) 5709 968.2 0 XP_006718676 (OMIM: 610879) PREDICTED: serine/thre ( 873) 5709 968.2 0 NP_001157633 (OMIM: 610879) serine/threonine-prote ( 873) 5709 968.2 0 XP_011543441 (OMIM: 610879) PREDICTED: serine/thre ( 883) 5682 963.7 0 XP_006718671 (OMIM: 610879) PREDICTED: serine/thre ( 883) 5679 963.2 0 XP_011543440 (OMIM: 610879) PREDICTED: serine/thre ( 889) 5657 959.5 0 XP_011543439 (OMIM: 610879) PREDICTED: serine/thre ( 889) 5657 959.5 0 XP_011543437 (OMIM: 610879) PREDICTED: serine/thre ( 889) 5657 959.5 0 XP_011543438 (OMIM: 610879) PREDICTED: serine/thre ( 889) 5657 959.5 0 XP_006718675 (OMIM: 610879) PREDICTED: serine/thre ( 877) 5379 912.9 0 XP_006718677 (OMIM: 610879) PREDICTED: serine/thre ( 867) 5287 897.5 0 XP_016873455 (OMIM: 610879) PREDICTED: serine/thre ( 867) 5287 897.5 0 NP_001157634 (OMIM: 610879) serine/threonine-prote ( 867) 5287 897.5 0 XP_016873466 (OMIM: 610879) PREDICTED: serine/thre ( 788) 5172 878.2 0 XP_016873467 (OMIM: 610879) PREDICTED: serine/thre ( 788) 5172 878.2 0 XP_016873469 (OMIM: 610879) PREDICTED: serine/thre ( 782) 5106 867.2 0 XP_016873468 (OMIM: 610879) PREDICTED: serine/thre ( 786) 4776 811.9 0 XP_016873472 (OMIM: 610879) PREDICTED: serine/thre ( 630) 4116 701.3 3.8e-201 XP_011543443 (OMIM: 610879) PREDICTED: serine/thre ( 872) 3689 629.8 1.7e-179 XP_016873459 (OMIM: 610879) PREDICTED: serine/thre ( 856) 3618 617.9 6.4e-176 XP_016873458 (OMIM: 610879) PREDICTED: serine/thre ( 856) 3618 617.9 6.4e-176 XP_016873456 (OMIM: 610879) PREDICTED: serine/thre ( 862) 3612 616.9 1.3e-175 XP_016873457 (OMIM: 610879) PREDICTED: serine/thre ( 862) 3612 616.9 1.3e-175 XP_016873462 (OMIM: 610879) PREDICTED: serine/thre ( 850) 3396 580.7 1e-164 XP_016873461 (OMIM: 610879) PREDICTED: serine/thre ( 850) 3396 580.7 1e-164 XP_016873460 (OMIM: 610879) PREDICTED: serine/thre ( 850) 3396 580.7 1e-164 XP_011543444 (OMIM: 610879) PREDICTED: serine/thre ( 860) 3396 580.7 1e-164 XP_016873463 (OMIM: 610879) PREDICTED: serine/thre ( 844) 3394 580.3 1.3e-164 XP_011543445 (OMIM: 610879) PREDICTED: serine/thre ( 854) 3394 580.3 1.3e-164 NP_001157635 (OMIM: 610879) serine/threonine-prote ( 844) 3386 579.0 3.2e-164 XP_006718681 (OMIM: 610879) PREDICTED: serine/thre ( 844) 3386 579.0 3.2e-164 XP_006718684 (OMIM: 610879) PREDICTED: serine/thre ( 827) 3382 578.3 5e-164 XP_006718690 (OMIM: 610879) PREDICTED: serine/thre ( 601) 3378 577.6 6e-164 XP_016873464 (OMIM: 610879) PREDICTED: serine/thre ( 833) 3380 578.0 6.3e-164 XP_011543447 (OMIM: 610879) PREDICTED: serine/thre ( 838) 3225 552.0 4.2e-156 XP_016873470 (OMIM: 610879) PREDICTED: serine/thre ( 765) 3015 516.8 1.5e-145 XP_016873471 (OMIM: 610879) PREDICTED: serine/thre ( 753) 2783 477.9 7.5e-134 XP_016873465 (OMIM: 610879) PREDICTED: serine/thre ( 805) 2147 371.4 9.5e-102 NP_001157636 (OMIM: 610879) serine/threonine-prote ( 791) 2138 369.9 2.7e-101 XP_006718687 (OMIM: 610879) PREDICTED: serine/thre ( 793) 2138 369.9 2.7e-101 NP_060782 (OMIM: 610879) serine/threonine-protein ( 793) 2138 369.9 2.7e-101 XP_006718686 (OMIM: 610879) PREDICTED: serine/thre ( 803) 2138 369.9 2.7e-101 XP_006718685 (OMIM: 610879) PREDICTED: serine/thre ( 803) 2138 369.9 2.7e-101 NP_055746 (OMIM: 610875) serine/threonine-protein ( 881) 2135 369.4 4.1e-101 XP_016873473 (OMIM: 610879) PREDICTED: serine/thre ( 619) 1912 332.0 5.4e-90 >>XP_011543442 (OMIM: 610879) PREDICTED: serine/threonin (879 aa) initn: 5775 init1: 5775 opt: 5775 Z-score: 5232.2 bits: 979.3 E(85289): 0 Smith-Waterman score: 5775; 100.0% identity (100.0% similar) in 879 aa overlap (1-879:1-879) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE 790 800 810 820 830 840 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV ::::::::::::::::::::::::::::::::::::::: XP_011 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV 850 860 870 >>NP_001157632 (OMIM: 610879) serine/threonine-protein p (879 aa) initn: 5775 init1: 5775 opt: 5775 Z-score: 5232.2 bits: 979.3 E(85289): 0 Smith-Waterman score: 5775; 100.0% identity (100.0% similar) in 879 aa overlap (1-879:1-879) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE 790 800 810 820 830 840 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV ::::::::::::::::::::::::::::::::::::::: NP_001 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV 850 860 870 >>XP_016873451 (OMIM: 610879) PREDICTED: serine/threonin (879 aa) initn: 5775 init1: 5775 opt: 5775 Z-score: 5232.2 bits: 979.3 E(85289): 0 Smith-Waterman score: 5775; 100.0% identity (100.0% similar) in 879 aa overlap (1-879:1-879) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE 790 800 810 820 830 840 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV ::::::::::::::::::::::::::::::::::::::: XP_016 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV 850 860 870 >>XP_016873454 (OMIM: 610879) PREDICTED: serine/threonin (873 aa) initn: 3564 init1: 3564 opt: 5712 Z-score: 5175.2 bits: 968.7 E(85289): 0 Smith-Waterman score: 5712; 99.3% identity (99.3% similar) in 879 aa overlap (1-879:1-873) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL ::: ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQ------QMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE 780 790 800 810 820 830 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV ::::::::::::::::::::::::::::::::::::::: XP_016 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV 840 850 860 870 >>XP_016873453 (OMIM: 610879) PREDICTED: serine/threonin (873 aa) initn: 3564 init1: 3564 opt: 5712 Z-score: 5175.2 bits: 968.7 E(85289): 0 Smith-Waterman score: 5712; 99.3% identity (99.3% similar) in 879 aa overlap (1-879:1-873) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL ::: ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQ------QMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE 780 790 800 810 820 830 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV ::::::::::::::::::::::::::::::::::::::: XP_016 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV 840 850 860 870 >>XP_016873452 (OMIM: 610879) PREDICTED: serine/threonin (873 aa) initn: 5718 init1: 5345 opt: 5709 Z-score: 5172.5 bits: 968.2 E(85289): 0 Smith-Waterman score: 5709; 99.2% identity (99.2% similar) in 879 aa overlap (1-879:1-873) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_016 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKS------EEGKLSTSQDAACKDAE 790 800 810 820 830 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV ::::::::::::::::::::::::::::::::::::::: XP_016 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV 840 850 860 870 >>XP_006718676 (OMIM: 610879) PREDICTED: serine/threonin (873 aa) initn: 5718 init1: 5345 opt: 5709 Z-score: 5172.5 bits: 968.2 E(85289): 0 Smith-Waterman score: 5709; 99.2% identity (99.2% similar) in 879 aa overlap (1-879:1-873) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_006 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKS------EEGKLSTSQDAACKDAE 790 800 810 820 830 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV ::::::::::::::::::::::::::::::::::::::: XP_006 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV 840 850 860 870 >>NP_001157633 (OMIM: 610879) serine/threonine-protein p (873 aa) initn: 5718 init1: 5345 opt: 5709 Z-score: 5172.5 bits: 968.2 E(85289): 0 Smith-Waterman score: 5709; 99.2% identity (99.2% similar) in 879 aa overlap (1-879:1-873) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::: ::::::::::::::::: NP_001 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKS------EEGKLSTSQDAACKDAE 790 800 810 820 830 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV ::::::::::::::::::::::::::::::::::::::: NP_001 ECPETAEAKCAAPRPPSSSPEQRTGQPSAPGDTSVNGPV 840 850 860 870 >>XP_011543441 (OMIM: 610879) PREDICTED: serine/threonin (883 aa) initn: 3668 init1: 3564 opt: 5682 Z-score: 5148.0 bits: 963.7 E(85289): 0 Smith-Waterman score: 5682; 98.2% identity (98.2% similar) in 889 aa overlap (1-879:1-883) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL ::: ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLQ------QMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 600 610 620 630 640 650 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 660 670 680 690 700 710 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 720 730 740 750 760 770 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE 780 790 800 810 820 830 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQ----------RTGQPSAPGDTSVNGPV :::::::::::::::::::::: ::::::::::::::::: XP_011 ECPETAEAKCAAPRPPSSSPEQSASDACLLLLRTGQPSAPGDTSVNGPV 840 850 860 870 880 >>XP_006718671 (OMIM: 610879) PREDICTED: serine/threonin (883 aa) initn: 5704 init1: 5345 opt: 5679 Z-score: 5145.3 bits: 963.2 E(85289): 0 Smith-Waterman score: 5679; 98.1% identity (98.1% similar) in 889 aa overlap (1-879:1-883) 10 20 30 40 50 60 pF1KA1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KA1 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KA1 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KA1 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KA1 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRPTFEGHIEICPPGMSHSACS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KA1 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VNKSVLEAIRGRLGSFHELLLEPPKKSVMKTTWGVLDPPVGNTRLNVIRLISSLLQTNTS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KA1 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SINGDLMELNSIGVILNMFFKYTWNNFLHTQVEICIALILASPFENTENATITDQDSTGD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KA1 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIANCIVHSTDKGPNSAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KA1 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDLVTTCHIHSSSDDEIDFKETGFSQDS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KA1 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLQQAFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSDINFTLNTNESGNIAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KA1 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FEACCKERIQQFDDGGSDEEDIWEEKHIAFTPESQRRSSSGSTDSEESTDSEEEDGAKQD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KA1 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFEPSSANTEDKMEVDLSEPPNWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGW 670 680 690 700 710 720 730 740 750 760 770 780 pF1KA1 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASFSEFTSSLSTKDSLRSNSPVEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGE 730 740 750 760 770 780 790 800 810 820 830 840 pF1KA1 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKRVLKSYREEGKLSTSQDAACKDAE :::::::::::::::::::::::::::::::::::: ::::::::::::::::: XP_006 EDAESTDKVTETVMNGGMKETLSLTVDAKTETAVFKS------EEGKLSTSQDAACKDAE 790 800 810 820 830 850 860 870 pF1KA1 ECPETAEAKCAAPRPPSSSPEQ----------RTGQPSAPGDTSVNGPV :::::::::::::::::::::: ::::::::::::::::: XP_006 ECPETAEAKCAAPRPPSSSPEQSASDACLLLLRTGQPSAPGDTSVNGPV 840 850 860 870 880 879 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 11:17:21 2016 done: Thu Nov 3 11:17:23 2016 Total Scan time: 14.790 Total Display time: 0.370 Function used was FASTA [36.3.4 Apr, 2011]