Result of FASTA (omim) for
pF1KA1477
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1477, 758 aa
1>>>pF1KA1477 758 - 758 aa - 758 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.4960+/-0.000595; mu= -25.3241+/- 0.036
mean_var=816.2680+/-181.950, 0's: 0 Z-trim(116.2): 979 B-trim: 0 in 0/59
Lambda= 0.044891
statistics sampled from 25953 (27129) to 25953 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.318), width: 16
Scan time: 10.160
The best scores are: opt bits E(85289)
NP_001273057 (OMIM: 606511) serine/threonine-prote ( 758) 4991 340.3 1.8e-92
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 4242 291.8 7.4e-78
XP_016856796 (OMIM: 606511) PREDICTED: serine/thre ( 670) 4234 291.2 9.6e-78
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 4230 291.0 1.3e-77
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 3485 242.8 4.3e-63
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 3480 242.4 5.4e-63
XP_016856795 (OMIM: 606511) PREDICTED: serine/thre ( 685) 3477 242.2 5.6e-63
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 3473 242.0 7.4e-63
XP_006711389 (OMIM: 606511) PREDICTED: serine/thre ( 708) 3467 241.5 8.9e-63
XP_016856794 (OMIM: 606511) PREDICTED: serine/thre ( 686) 3465 241.4 9.6e-63
XP_011507864 (OMIM: 606511) PREDICTED: serine/thre ( 686) 3465 241.4 9.6e-63
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 2258 163.3 3.6e-39
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 2243 162.3 6.7e-39
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 2243 162.3 7.1e-39
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 2231 161.5 1.2e-38
XP_016876787 (OMIM: 602678) PREDICTED: MAP/microtu ( 665) 1879 138.7 7.8e-32
XP_016876784 (OMIM: 602678) PREDICTED: MAP/microtu ( 680) 1879 138.7 7.9e-32
XP_011535071 (OMIM: 602678) PREDICTED: MAP/microtu ( 673) 1878 138.6 8.2e-32
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 1879 138.7 8.3e-32
XP_016876783 (OMIM: 602678) PREDICTED: MAP/microtu ( 689) 1878 138.6 8.4e-32
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 1879 138.7 8.4e-32
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 1878 138.6 8.8e-32
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 1878 138.7 8.9e-32
XP_016876785 (OMIM: 602678) PREDICTED: MAP/microtu ( 674) 1875 138.4 9.4e-32
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 1875 138.5 1e-31
XP_016876793 (OMIM: 602678) PREDICTED: MAP/microtu ( 598) 1858 137.2 1.9e-31
XP_016876791 (OMIM: 602678) PREDICTED: MAP/microtu ( 613) 1858 137.3 1.9e-31
XP_016876790 (OMIM: 602678) PREDICTED: MAP/microtu ( 622) 1857 137.2 2e-31
XP_016876789 (OMIM: 602678) PREDICTED: MAP/microtu ( 622) 1857 137.2 2e-31
XP_016876792 (OMIM: 602678) PREDICTED: MAP/microtu ( 607) 1854 137.0 2.3e-31
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 1850 136.8 2.8e-31
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 1736 129.5 5.2e-29
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 1730 129.1 7e-29
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 1730 129.1 7.1e-29
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 1724 128.7 9.2e-29
XP_016876799 (OMIM: 602678) PREDICTED: MAP/microtu ( 572) 1704 127.2 1.8e-28
XP_016876800 (OMIM: 602678) PREDICTED: MAP/microtu ( 572) 1704 127.2 1.8e-28
XP_016876798 (OMIM: 602678) PREDICTED: MAP/microtu ( 587) 1704 127.3 1.9e-28
XP_016876795 (OMIM: 602678) PREDICTED: MAP/microtu ( 596) 1703 127.2 2e-28
XP_016876796 (OMIM: 602678) PREDICTED: MAP/microtu ( 596) 1703 127.2 2e-28
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 1689 126.4 4.1e-28
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 1689 126.4 4.2e-28
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 1689 126.4 4.2e-28
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 1689 126.4 4.2e-28
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 1689 126.4 4.3e-28
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 1689 126.4 4.3e-28
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 1677 125.6 7.1e-28
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 1677 125.6 7.3e-28
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 1677 125.6 7.3e-28
XP_006723370 (OMIM: 606495) PREDICTED: MAP/microtu ( 685) 1582 119.4 4.9e-26
>>NP_001273057 (OMIM: 606511) serine/threonine-protein k (758 aa)
initn: 4991 init1: 4991 opt: 4991 Z-score: 1781.1 bits: 340.3 E(85289): 1.8e-92
Smith-Waterman score: 4991; 99.9% identity (99.9% similar) in 758 aa overlap (1-758:1-758)
10 20 30 40 50 60
pF1KA1 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 EVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 KELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 YTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 SGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 NSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSSTIPSNNVYSGGSMARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSSTIPSNNVYSGGSMARR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 NTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 KVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 RSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRSTSGEPKERDKEEGKDSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRSTSGEPKERDKEEGKDSKP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA1 RSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEM
670 680 690 700 710 720
730 740 750
pF1KA1 EVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELML
:::::::::::::::::::::::::::::::::::: :
NP_001 EVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
730 740 750
>>NP_001273055 (OMIM: 606511) serine/threonine-protein k (780 aa)
initn: 4992 init1: 4221 opt: 4242 Z-score: 1518.8 bits: 291.8 E(85289): 7.4e-78
Smith-Waterman score: 4937; 97.1% identity (97.1% similar) in 780 aa overlap (1-758:1-780)
10 20 30 40 50 60
pF1KA1 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
10 20 30 40 50 60
70 80 90 100 110
pF1KA1 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV
70 80 90 100 110 120
120 130 140 150
pF1KA1 ---------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
:::::::::::::::::::::::::::::::::::::::
NP_001 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA1 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA1 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA1 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA1 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA1 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA1 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA1 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA1 RTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKF
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA1 VRRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQK
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA1 ERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELML
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 ERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
730 740 750 760 770 780
>>XP_016856796 (OMIM: 606511) PREDICTED: serine/threonin (670 aa)
initn: 4272 init1: 4215 opt: 4234 Z-score: 1516.7 bits: 291.2 E(85289): 9.6e-78
Smith-Waterman score: 4234; 96.6% identity (98.1% similar) in 667 aa overlap (96-758:4-670)
70 80 90 100 110 120
pF1KA1 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK----ILNHPNIGE
:: .. :::. .. : .... . ::
XP_016 MKILNHPNIVKLFEVIETEKTLYLVMEYASGGE
10 20 30
130 140 150 160 170 180
pF1KA1 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA1 SNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA1 ELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPY
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA1 TEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSS
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA1 GNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQAN
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA1 SVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSSTIPSNNVYSGGSMARRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSSTIPSNNVYSGGSMARRN
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA1 TYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPIK
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA1 VTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERR
460 470 480 490 500 510
610 620 630 640 650 660
pF1KA1 SVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRSTSGEPKERDKEEGKDSKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRSTSGEPKERDKEEGKDSKPR
520 530 540 550 560 570
670 680 690 700 710 720
pF1KA1 SLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEME
580 590 600 610 620 630
730 740 750
pF1KA1 VCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELML
::::::::::::::::::::::::::::::::::: :
XP_016 VCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
640 650 660 670
>>XP_005273191 (OMIM: 606511) PREDICTED: serine/threonin (781 aa)
initn: 4214 init1: 2909 opt: 4230 Z-score: 1514.6 bits: 291.0 E(85289): 1.3e-77
Smith-Waterman score: 4925; 96.9% identity (96.9% similar) in 781 aa overlap (1-758:1-781)
10 20 30 40 50 60
pF1KA1 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
10 20 30 40 50 60
70 80 90 100 110
pF1KA1 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV
70 80 90 100 110 120
120 130 140 150
pF1KA1 ---------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
:::::::::::::::::::::::::::::::::::::::
XP_005 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA1 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA1 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA1 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA1 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA1 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA1 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA1 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPG-TTQRVPAASPSAHSISTATP
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_005 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGSTTQRVPAASPSAHSISTATP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA1 DRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA1 FVRRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVRRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA1 KERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELK
730 740 750 760 770 780
pF1KA1 L
:
XP_005 L
>>NP_061120 (OMIM: 606511) serine/threonine-protein kina (795 aa)
initn: 4218 init1: 3452 opt: 3485 Z-score: 1253.7 bits: 242.8 E(85289): 4.3e-63
Smith-Waterman score: 4897; 95.2% identity (95.2% similar) in 795 aa overlap (1-758:1-795)
10 20 30 40 50 60
pF1KA1 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
10 20 30 40 50 60
70 80 90 100 110
pF1KA1 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV
70 80 90 100 110 120
120 130 140 150
pF1KA1 ---------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
:::::::::::::::::::::::::::::::::::::::
NP_061 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA1 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA1 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA1 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA1 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA1 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA1 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA1 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA1 RTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKF
610 620 630 640 650 660
640 650 660 670 680
pF1KA1 VRR---------------STSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMRE
::: ::::::::::::::::::::::::::::::::::::::::::
NP_061 VRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMRE
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA1 IRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSI
730 740 750 760 770 780
750
pF1KA1 AFKNIASKIANELML
::::::::::::: :
NP_061 AFKNIASKIANELKL
790
>>XP_011507863 (OMIM: 606511) PREDICTED: serine/threonin (788 aa)
initn: 3675 init1: 2909 opt: 3480 Z-score: 1252.0 bits: 242.4 E(85289): 5.4e-63
Smith-Waterman score: 4776; 94.9% identity (95.0% similar) in 780 aa overlap (17-758:9-788)
10 20 30 40 50 60
pF1KA1 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
.:::::::::::::::::::::::::::::::::::::::::::
XP_011 MPATSAMSSHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
10 20 30 40 50
70 80 90 100 110
pF1KA1 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV
60 70 80 90 100 110
120 130 140 150
pF1KA1 ---------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
:::::::::::::::::::::::::::::::::::::::
XP_011 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KA1 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KA1 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KA1 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KA1 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
360 370 380 390 400 410
400 410 420 430 440 450
pF1KA1 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
420 430 440 450 460 470
460 470 480 490 500 510
pF1KA1 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
480 490 500 510 520 530
520 530 540 550 560 570
pF1KA1 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPG-TTQRVPAASPSAHSISTATP
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGSTTQRVPAASPSAHSISTATP
540 550 560 570 580 590
580 590 600 610 620 630
pF1KA1 DRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSK
600 610 620 630 640 650
640 650 660 670 680
pF1KA1 FVRR---------------STSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMR
:::: :::::::::::::::::::::::::::::::::::::::::
XP_011 FVRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMR
660 670 680 690 700 710
690 700 710 720 730 740
pF1KA1 EIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTS
720 730 740 750 760 770
750
pF1KA1 IAFKNIASKIANELML
:::::::::::::: :
XP_011 IAFKNIASKIANELKL
780
>>XP_016856795 (OMIM: 606511) PREDICTED: serine/threonin (685 aa)
initn: 4217 init1: 3451 opt: 3477 Z-score: 1251.7 bits: 242.2 E(85289): 5.6e-63
Smith-Waterman score: 4194; 94.4% identity (95.9% similar) in 682 aa overlap (96-758:4-685)
70 80 90 100 110 120
pF1KA1 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK----ILNHPNIGE
:: .. :::. .. : .... . ::
XP_016 MKILNHPNIVKLFEVIETEKTLYLVMEYASGGE
10 20 30
130 140 150 160 170 180
pF1KA1 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA1 SNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA1 ELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPY
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA1 TEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSS
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA1 GNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQAN
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA1 SVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSSTIPSNNVYSGGSMARRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSSTIPSNNVYSGGSMARRN
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA1 TYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPIK
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA1 VTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERR
460 470 480 490 500 510
610 620 630 640
pF1KA1 SVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRR---------------STSGE
:::::::::::::::::::::::::::::::::::::::: :::::
XP_016 SVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRDPSEGEASGRTDTSRSTSGE
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA1 PKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCV
580 590 600 610 620 630
710 720 730 740 750
pF1KA1 HGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELML
:::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 HGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
640 650 660 670 680
>>NP_001273053 (OMIM: 606511) serine/threonine-protein k (796 aa)
initn: 3675 init1: 2909 opt: 3473 Z-score: 1249.5 bits: 242.0 E(85289): 7.4e-63
Smith-Waterman score: 4885; 95.1% identity (95.1% similar) in 796 aa overlap (1-758:1-796)
10 20 30 40 50 60
pF1KA1 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
10 20 30 40 50 60
70 80 90 100 110
pF1KA1 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV
70 80 90 100 110 120
120 130 140 150
pF1KA1 ---------------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
:::::::::::::::::::::::::::::::::::::::
NP_001 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA1 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA1 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA1 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA1 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA1 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA1 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA1 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPG-TTQRVPAASPSAHSISTATP
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_001 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGSTTQRVPAASPSAHSISTATP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA1 DRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSK
610 620 630 640 650 660
640 650 660 670 680
pF1KA1 FVRR---------------STSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMR
:::: :::::::::::::::::::::::::::::::::::::::::
NP_001 FVRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMR
670 680 690 700 710 720
690 700 710 720 730 740
pF1KA1 EIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTS
730 740 750 760 770 780
750
pF1KA1 IAFKNIASKIANELML
:::::::::::::: :
NP_001 IAFKNIASKIANELKL
790
>>XP_006711389 (OMIM: 606511) PREDICTED: serine/threonin (708 aa)
initn: 3675 init1: 2909 opt: 3467 Z-score: 1248.0 bits: 241.5 E(85289): 8.9e-63
Smith-Waterman score: 4226; 93.8% identity (94.0% similar) in 699 aa overlap (98-758:10-708)
70 80 90 100 110
pF1KA1 KGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI--------
: .: ::::::::::::::::
XP_006 MTSGSLCPGPPGLPTLFREVRIMKILNHPNIVKLFEVIE
10 20 30
120 130 140 150 160
pF1KA1 --------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAEN
::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAEN
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA1 LLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA1 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMK
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA1 DRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYIL
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA1 LGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAG
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA1 PSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSST
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA1 IPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA1 RPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPG-TTQRVPAASPSAHSISTATPDRTRFPR
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_006 RPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGSTTQRVPAASPSAHSISTATPDRTRFPR
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA1 GSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRR---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRDPS
520 530 540 550 560 570
650 660 670 680
pF1KA1 ------------STSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLD
::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLD
580 590 600 610 620 630
690 700 710 720 730 740
pF1KA1 ANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIA
640 650 660 670 680 690
750
pF1KA1 SKIANELML
::::::: :
XP_006 SKIANELKL
700
>>XP_016856794 (OMIM: 606511) PREDICTED: serine/threonin (686 aa)
initn: 3674 init1: 2908 opt: 3465 Z-score: 1247.5 bits: 241.4 E(85289): 9.6e-63
Smith-Waterman score: 4182; 94.3% identity (95.8% similar) in 683 aa overlap (96-758:4-686)
70 80 90 100 110 120
pF1KA1 IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMK----ILNHPNIGE
:: .. :::. .. : .... . ::
XP_016 MKILNHPNIVKLFEVIETEKTLYLVMEYASGGE
10 20 30
130 140 150 160 170 180
pF1KA1 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGF
40 50 60 70 80 90
190 200 210 220 230 240
pF1KA1 SNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLK
100 110 120 130 140 150
250 260 270 280 290 300
pF1KA1 ELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPY
160 170 180 190 200 210
310 320 330 340 350 360
pF1KA1 TEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSS
220 230 240 250 260 270
370 380 390 400 410 420
pF1KA1 GNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQAN
280 290 300 310 320 330
430 440 450 460 470 480
pF1KA1 SVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSSTIPSNNVYSGGSMARRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPERKKSSTIPSNNVYSGGSMARRN
340 350 360 370 380 390
490 500 510 520 530 540
pF1KA1 TYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPIK
400 410 420 430 440 450
550 560 570 580 590 600
pF1KA1 VTLPTIKDGSEAYRPG-TTQRVPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRER
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLPTIKDGSEAYRPGSTTQRVPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRER
460 470 480 490 500 510
610 620 630 640
pF1KA1 RSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRR---------------STSG
::::::::::::::::::::::::::::::::::::::::: ::::
XP_016 RSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRDPSEGEASGRTDTSRSTSG
520 530 540 550 560 570
650 660 670 680 690 700
pF1KA1 EPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFC
580 590 600 610 620 630
710 720 730 740 750
pF1KA1 VHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELML
::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 VHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
640 650 660 670 680
758 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:15:28 2016 done: Wed Nov 2 21:15:30 2016
Total Scan time: 10.160 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]