Result of FASTA (omim) for
pF1KA1449
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA1449, 677 aa
1>>>pF1KA1449 677 - 677 aa - 677 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4759+/-0.000507; mu= 13.7520+/- 0.031
mean_var=176.6731+/-40.424, 0's: 0 Z-trim(111.4): 365 B-trim: 53 in 1/51
Lambda= 0.096491
statistics sampled from 19500 (19970) to 19500 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.583), E-opt: 0.2 (0.234), width: 16
Scan time: 11.020
The best scores are: opt bits E(85289)
NP_065890 (OMIM: 612167) WD repeat-containing prot ( 677) 4563 649.1 1.5e-185
XP_005265403 (OMIM: 612167) PREDICTED: WD repeat-c ( 707) 4354 620.1 8.9e-177
NP_001333155 (OMIM: 612167) WD repeat-containing p ( 620) 4153 592.0 2.2e-168
NP_001333157 (OMIM: 612167) WD repeat-containing p ( 607) 4100 584.6 3.6e-166
NP_001290331 (OMIM: 612167) WD repeat-containing p ( 595) 3959 565.0 2.9e-160
NP_001290332 (OMIM: 612167) WD repeat-containing p ( 668) 3905 557.5 5.6e-158
XP_011532273 (OMIM: 612167) PREDICTED: WD repeat-c ( 637) 3891 555.6 2.1e-157
NP_001333154 (OMIM: 612167) WD repeat-containing p ( 715) 3563 510.0 1.3e-143
NP_001333156 (OMIM: 612167) WD repeat-containing p ( 502) 3416 489.3 1.5e-137
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 303 55.7 3.1e-07
NP_004805 (OMIM: 607797) U5 small nuclear ribonucl ( 357) 298 55.1 5.4e-07
NP_006444 (OMIM: 605915) transducin beta-like prot ( 808) 294 55.0 1.3e-06
XP_016863001 (OMIM: 606990) PREDICTED: coatomer su ( 877) 274 52.2 9.6e-06
NP_004757 (OMIM: 606990) coatomer subunit beta' [H ( 906) 274 52.2 9.8e-06
XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 234 46.0 0.00021
XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 234 46.0 0.00021
XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 234 46.0 0.00021
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 234 46.1 0.00023
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 234 46.1 0.00024
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 234 46.1 0.00025
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 234 46.2 0.00026
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 234 46.2 0.00027
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 234 46.2 0.00027
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 234 46.2 0.00028
NP_001246 (OMIM: 603618) cell division cycle prote ( 499) 228 45.5 0.00057
NP_599027 (OMIM: 610091) WD repeat and SOCS box-co ( 275) 224 44.6 0.00058
NP_071767 (OMIM: 612190) target of rapamycin compl ( 326) 225 44.9 0.00059
NP_001186102 (OMIM: 612190) target of rapamycin co ( 326) 225 44.9 0.00059
NP_001186103 (OMIM: 612190) target of rapamycin co ( 326) 225 44.9 0.00059
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 225 44.9 0.00061
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 225 45.0 0.00068
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 225 45.0 0.00068
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 225 45.0 0.00068
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 225 45.0 0.00068
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 225 45.0 0.00069
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 225 45.0 0.00069
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 225 45.0 0.00069
NP_056441 (OMIM: 610091) WD repeat and SOCS box-co ( 421) 224 44.9 0.00076
NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 223 44.7 0.00084
NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 223 44.8 0.00094
XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 223 44.8 0.00094
NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 223 44.8 0.00094
NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 223 44.8 0.00094
XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 223 44.8 0.00094
XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 223 44.8 0.00094
XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 223 44.8 0.00094
XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 223 44.8 0.00094
XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 223 44.8 0.00094
NP_942593 (OMIM: 610767,611081) autophagy-related ( 444) 221 44.5 0.001
XP_005246143 (OMIM: 610767,611081) PREDICTED: auto ( 463) 221 44.5 0.0011
>>NP_065890 (OMIM: 612167) WD repeat-containing protein (677 aa)
initn: 4563 init1: 4563 opt: 4563 Z-score: 3452.2 bits: 649.1 E(85289): 1.5e-185
Smith-Waterman score: 4563; 100.0% identity (100.0% similar) in 677 aa overlap (1-677:1-677)
10 20 30 40 50 60
pF1KA1 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 ELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 ASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 LLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 YEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHF
610 620 630 640 650 660
670
pF1KA1 IWKSGGDLTLHYRQKST
:::::::::::::::::
NP_065 IWKSGGDLTLHYRQKST
670
>>XP_005265403 (OMIM: 612167) PREDICTED: WD repeat-conta (707 aa)
initn: 4354 init1: 4354 opt: 4354 Z-score: 3294.7 bits: 620.1 E(85289): 8.9e-177
Smith-Waterman score: 4354; 100.0% identity (100.0% similar) in 647 aa overlap (1-647:1-647)
10 20 30 40 50 60
pF1KA1 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA1 KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA1 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA1 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA1 ELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA1 ASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA1 SVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA1 PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA1 LLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA1 YEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHF
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVSGLEDYSPNFSSA
610 620 630 640 650 660
670
pF1KA1 IWKSGGDLTLHYRQKST
XP_005 GAHKELHAFGWGASTFRGALRSPGPLLPKAHPKAPLYCWGDFQRRDT
670 680 690 700
>>NP_001333155 (OMIM: 612167) WD repeat-containing prote (620 aa)
initn: 4153 init1: 4153 opt: 4153 Z-score: 3144.1 bits: 592.0 E(85289): 2.2e-168
Smith-Waterman score: 4153; 99.7% identity (99.7% similar) in 617 aa overlap (61-677:4-620)
40 50 60 70 80 90
pF1KA1 NGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTL
: :::::::::::::::::::::::::::
NP_001 MECQSAQDPYIASMEHHTDWVNDIVLCCNGKTL
10 20 30
100 110 120 130 140 150
pF1KA1 ISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLT
40 50 60 70 80 90
160 170 180 190 200 210
pF1KA1 ALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHT
100 110 120 130 140 150
220 230 240 250 260 270
pF1KA1 DNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSG
160 170 180 190 200 210
280 290 300 310 320 330
pF1KA1 GRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIH
220 230 240 250 260 270
340 350 360 370 380 390
pF1KA1 NFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVL
280 290 300 310 320 330
400 410 420 430 440 450
pF1KA1 KACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KA1 SSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVP
400 410 420 430 440 450
520 530 540 550 560 570
pF1KA1 PHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQ
460 470 480 490 500 510
580 590 600 610 620 630
pF1KA1 PHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEED
520 530 540 550 560 570
640 650 660 670
pF1KA1 IAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
580 590 600 610 620
>>NP_001333157 (OMIM: 612167) WD repeat-containing prote (607 aa)
initn: 4100 init1: 4100 opt: 4100 Z-score: 3104.3 bits: 584.6 E(85289): 3.6e-166
Smith-Waterman score: 4100; 100.0% identity (100.0% similar) in 607 aa overlap (71-677:1-607)
50 60 70 80 90 100
pF1KA1 ALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVK
::::::::::::::::::::::::::::::
NP_001 MEHHTDWVNDIVLCCNGKTLISASSDTTVK
10 20 30
110 120 130 140 150 160
pF1KA1 VWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA1 TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA1 DGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTD
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA1 LRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDN
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA1 DCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGK
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA1 VDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKL
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA1 NLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA1 GGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA1 KKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIE
520 530 540 550 560 570
650 660 670
pF1KA1 LLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
:::::::::::::::::::::::::::::::::::::
NP_001 LLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
580 590 600
>>NP_001290331 (OMIM: 612167) WD repeat-containing prote (595 aa)
initn: 3959 init1: 3959 opt: 3959 Z-score: 2998.4 bits: 565.0 E(85289): 2.9e-160
Smith-Waterman score: 3959; 99.2% identity (99.7% similar) in 593 aa overlap (85-677:3-595)
60 70 80 90 100 110
pF1KA1 RIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLR
:.. .::::::::::::::::::::::::
NP_001 MECQSAQVISASSDTTVKVWNAHKGFCMSTLR
10 20 30
120 130 140 150 160 170
pF1KA1 THKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSL
40 50 60 70 80 90
180 190 200 210 220 230
pF1KA1 AMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTI
100 110 120 130 140 150
240 250 260 270 280 290
pF1KA1 RLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEK
160 170 180 190 200 210
300 310 320 330 340 350
pF1KA1 APVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPD
220 230 240 250 260 270
360 370 380 390 400 410
pF1KA1 QVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMV
280 290 300 310 320 330
420 430 440 450 460 470
pF1KA1 YVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYW
340 350 360 370 380 390
480 490 500 510 520 530
pF1KA1 PRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSG
400 410 420 430 440 450
540 550 560 570 580 590
pF1KA1 GETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVR
460 470 480 490 500 510
600 610 620 630 640 650
pF1KA1 KVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDL
520 530 540 550 560 570
660 670
pF1KA1 RTVKHFIWKSGGDLTLHYRQKST
:::::::::::::::::::::::
NP_001 RTVKHFIWKSGGDLTLHYRQKST
580 590
>>NP_001290332 (OMIM: 612167) WD repeat-containing prote (668 aa)
initn: 3905 init1: 3905 opt: 3905 Z-score: 2957.2 bits: 557.5 E(85289): 5.6e-158
Smith-Waterman score: 4487; 98.7% identity (98.7% similar) in 677 aa overlap (1-677:1-668)
10 20 30 40 50 60
pF1KA1 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYV
:::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_001 QHKQDPYIASMEHHTDWVNDIVLCCNGKTL---------KVWNAHKGFCMSTLRTHKDYV
70 80 90 100 110
130 140 150 160 170 180
pF1KA1 KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA1 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA1 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKM
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA1 ELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGG
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA1 ASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWF
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA1 SVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVN
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA1 PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESM
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA1 LLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHV
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA1 YEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHF
600 610 620 630 640 650
670
pF1KA1 IWKSGGDLTLHYRQKST
:::::::::::::::::
NP_001 IWKSGGDLTLHYRQKST
660
>>XP_011532273 (OMIM: 612167) PREDICTED: WD repeat-conta (637 aa)
initn: 3891 init1: 3891 opt: 3891 Z-score: 2946.9 bits: 555.6 E(85289): 2.1e-157
Smith-Waterman score: 3891; 100.0% identity (100.0% similar) in 577 aa overlap (71-647:1-577)
50 60 70 80 90 100
pF1KA1 ALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVK
::::::::::::::::::::::::::::::
XP_011 MEHHTDWVNDIVLCCNGKTLISASSDTTVK
10 20 30
110 120 130 140 150 160
pF1KA1 VWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KA1 TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KA1 DGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTD
160 170 180 190 200 210
290 300 310 320 330 340
pF1KA1 LRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDN
220 230 240 250 260 270
350 360 370 380 390 400
pF1KA1 DCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGK
280 290 300 310 320 330
410 420 430 440 450 460
pF1KA1 VDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKL
340 350 360 370 380 390
470 480 490 500 510 520
pF1KA1 NLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNGYFQVPPHTPVIFGEA
400 410 420 430 440 450
530 540 550 560 570 580
pF1KA1 GGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KA1 KKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQEKEEDIAVLAEEKIE
520 530 540 550 560 570
650 660 670
pF1KA1 LLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
:::::::
XP_011 LLCQDQVSGLEDYSPNFSSAGAHKELHAFGWGASTFRGALRSPGPLLPKAHPKAPLYCWG
580 590 600 610 620 630
>>NP_001333154 (OMIM: 612167) WD repeat-containing prote (715 aa)
initn: 4546 init1: 3498 opt: 3563 Z-score: 2699.5 bits: 510.0 E(85289): 1.3e-143
Smith-Waterman score: 4430; 94.5% identity (94.6% similar) in 709 aa overlap (7-677:7-715)
10 20 30 40 50 60
pF1KA1 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA1 QHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYV
70 80 90 100 110 120
130 140 150 160
pF1KA1 KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTT-------------------
::::::::::::::::::::::::::::::::::::::::.
NP_001 KALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTSLHRESVSYFESASTYSVLA
130 140 150 160 170 180
170 180 190 200
pF1KA1 -------------------SSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAK
:::::::::::::::::::::::::::::::::::::::::
NP_001 PKSMIEQQRASSSLQSKNASSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KA1 LMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVND
250 260 270 280 290 300
270 280 290 300 310 320
pF1KA1 AFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVN
310 320 330 340 350 360
330 340 350 360 370 380
pF1KA1 KWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNN
370 380 390 400 410 420
390 400 410 420 430 440
pF1KA1 NVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAW
430 440 450 460 470 480
450 460 470 480 490 500
pF1KA1 VSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQK
490 500 510 520 530 540
510 520 530 540 550 560
pF1KA1 GNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKF
550 560 570 580 590 600
570 580 590 600 610 620
pF1KA1 NKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKP
610 620 630 640 650 660
630 640 650 660 670
pF1KA1 GEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
670 680 690 700 710
>>NP_001333156 (OMIM: 612167) WD repeat-containing prote (502 aa)
initn: 3416 init1: 3416 opt: 3416 Z-score: 2590.7 bits: 489.3 E(85289): 1.5e-137
Smith-Waterman score: 3416; 100.0% identity (100.0% similar) in 502 aa overlap (176-677:1-502)
150 160 170 180 190 200
pF1KA1 VNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMK
::::::::::::::::::::::::::::::
NP_001 MNQLGTIIVSGSTEKVLRVWDPRTCAKLMK
10 20 30
210 220 230 240 250 260
pF1KA1 LKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFT
40 50 60 70 80 90
270 280 290 300 310 320
pF1KA1 HVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWT
100 110 120 130 140 150
330 340 350 360 370 380
pF1KA1 LKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVA
160 170 180 190 200 210
390 400 410 420 430 440
pF1KA1 YWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSA
220 230 240 250 260 270
450 460 470 480 490 500
pF1KA1 KDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVNPMDEEENEVNHVNGEQENRVQKGNG
280 290 300 310 320 330
510 520 530 540 550 560
pF1KA1 YFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETESMLLNETVPQWVIDITVDKNMPKFNKI
340 350 360 370 380 390
570 580 590 600 610 620
pF1KA1 PFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPGEQ
400 410 420 430 440 450
630 640 650 660 670
pF1KA1 EKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST
460 470 480 490 500
>>NP_006089 (OMIM: 176981) receptor of activated protein (317 aa)
initn: 176 init1: 147 opt: 303 Z-score: 250.9 bits: 55.7 E(85289): 3.1e-07
Smith-Waterman score: 304; 26.4% identity (56.7% similar) in 307 aa overlap (31-325:15-303)
10 20 30 40 50
pF1KA1 MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNG-VNALQLDPAL-NRLFTAGRDSIIRIWS
:: :. . : . . ...:.::. : .:.
NP_006 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWK
10 20 30 40
60 70 80 90 100 110
pF1KA1 VNQHKQDPYIA--SMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTH
... . . : ... :. .:.:.:. .:. .:.: : :...:. : . :
NP_006 LTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGH
50 60 70 80 90 100
120 130 140 150 160 170
pF1KA1 KDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAM
: ..:...:.. ..:.. :. : :: ::: . . :: : : . : ..
NP_006 TKDVLSVAFSSDNRQIVSGSRDKTIKLW--NTLG---VCKYTVQDESHS-EWVSCVRFSP
110 120 130 140 150
180 190 200 210 220 230
pF1KA1 NQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRL
:. . :::: . .:...::. .: . ::: .... .. ::. : ::..:: :
NP_006 NSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAML
160 170 180 190 200 210
240 250 260 270 280 290
pF1KA1 WSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAP
:.:.. . . : : : .. .:. .: .: :. .:.:.. : :
NP_006 WDLNEGKHLYTL---DGG----DIINAL--CFSP--NRYWLCAAT-GPSIKIWDLEGKII
220 230 240 250 260
300 310 320 330 340
pF1KA1 V--LKMEL---DRSADPPPAI---WVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITP
: ::.:. . .:.:: : : .. .:
NP_006 VDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR
270 280 290 300 310
350 360 370 380 390 400
pF1KA1 LCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIK
677 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 11:05:47 2016 done: Thu Nov 3 11:05:49 2016
Total Scan time: 11.020 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]